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Long Term Memory

Date post: 22-Feb-2016
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Maintenance Rehearsal. Sensory Memory. Working or Short-term Memory. Encoding. Attention. Long-term memory. Sensory Input. Retrieval. Long Term Memory. Function = organizes and stores info. More passive form of storage than working memory - PowerPoint PPT Presentation
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Long Term Memory Function = organizes and stores info. More passive form of storage than working memory Capacity = unlimited. Average adult = 100 billion neurons, each of which can make perhaps 5,000 to 10,000 synaptic connections with other neurons five hundred trillion to a thousand trillion synapses Duration = thought be some to be permanent Long-term memory Working or Short-term Memory Sensory Input Sensory Memory Attention Encoding Retrieval Maintenance Rehearsal
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Page 1: Long Term Memory

Long Term Memory• Function = organizes and stores info. More passive form of storage than

working memory• Capacity = unlimited. Average adult = 100 billion neurons, each of which

can make perhaps 5,000 to 10,000 synaptic connections with other neurons five hundred trillion to a thousand trillion synapses

• Duration = thought be some to be permanent

Long-term memory

Working orShort-term

Memory

Sensory

Input

Sensory Memory

Attention Encoding

Retrieval

Maintenance Rehearsal

Page 2: Long Term Memory

History Channel: The Brain• Start at scene 12 or 58:00 of DVD 71• What is the function of memory?• Describe Lashly’s rat maze experiment in the 1920s. What

did he discover?• What is the capacity of long-term memory? • Who is Stephen Wiltshire? What is unique about his

memory? How is his brain different from a “normal” brain? • Who is Clive Wearing? What type of memory loss does he

suffer from and why? How has he changed over time? Why?

Page 3: Long Term Memory

SemanticFacts/General

Knowledge

EpisodicExperienced

events

ProceduralSkills

Motor/Cognitive

Classical Conditioning

Explicit (Declarative)knowing you know something

conscious recall

Implicit (Non-declarative)knowing how to do something

(but not know you know)without conscious recall

Types of Long-Term Memory

Medial Temporal Lobe / Hippocampus / Frontal Lobe

Cerebellum

http://ngm.nationalgeographic.com/2007/11/memory/brain-interactive

Page 4: Long Term Memory

Memory Loss• Anterograde amnesia – means forward; can’t form new memories.

– Effects of the accident are working forward in time and patient is unable to remember things that have happened since the accident

• Retrograde amnesia – means backward; can’t remember old memories . • Hit by a car at noon on Tuesday. Patient regained consciousness

Tuesday night and it is now Wednesday. Patient can’t remember the accident or anything that happened Tuesday morning before the accident.

Page 5: Long Term Memory

Famous Amnesic Patients• EP – herpes simplex virus chewed its way though his brain, destroying his medial temporal

lobe (which contains hippocampus and amygdala)• HM – surgery destroyed hippocampus to stop epileptic seizures

– Surgery was effective in reducing seizures BUT, had other side effects as well– Can remember explicit memories acquired before the surgery

• e.g., old addresses, normal vocabulary – Cannot form NEW explicit memories

• e.g., remembering the name of someone he met 30 minutes prior• cannot name new world leaders or performers• can recognize a picture of himself from before his surgery but not from after and

doesn’t recognize himself in a mirror• Clive Wearing - renowned European conductor; viral encephalitis (inflammation of the brain

tissue) destroyed his hippocampus. – While brain damage has totally obliterated Clive's explicit memory--his ability to

remember new facts or events--his implicit memory remains intact; he still has language and musical skills, although he is not consciously aware of his ability to play music.

• All suffer deficits in explicit, but not implicit memory• All suffer from anterograde and retrograde amnesia

Page 6: Long Term Memory

Explicit Memory Memories are those of which

one is consciously aware. EX: I may have an explicit memory of playing a particular golf course

1. Episodic = memories are those for personally experienced events

2. Semantic = memories are for general factual knowledge

Medial Temporal Lobe Hippocampus (left – trouble

remembering verbal info / right – trouble recalling visual designs and locations)

Frontal Lobe

Page 7: Long Term Memory

Implicit Memory

Memories are those of which one is not conscious. EX: one may have implicit memories of how to tie one’s shoe but not be able to describe to another how to do it1. Procedural = memories are those

that relate to skills or habits. Learn how to do something, often through classical conditioning, but cannot know or declare they know.

2. Classical Conditioning Cerebellum

Page 8: Long Term Memory

Synaptic Changes

• Release more serotonin at certain synapses when learning occurs

• Glutamate enhances long-term potentiation = an increase in the release of neurotransmitters or increase in receptors sites on receiving neuron. Rapidly stimulating memory-circuit connections causes those synapses to become more efficient at transmitting signals; takes less of a signal to recall a memory.

Page 9: Long Term Memory

Review! Pieces of Mind: Remembering What Matters

• What is the role of adrenaline in the formation of memory? How do we know? Describe the experiments with the rats and people.

• What is the role of the amygdala in the formation of memory?

Page 10: Long Term Memory

Stress Hormones and Memory Formation• Prolonged stress

disrupts LTP • Moderate stress

enhances LTP• When subjects are given

a beta blocker to stall the activation of the SNS, the experimental group did not remember the livelier story any better than the controls remembered theirs. The drug disrupts stress-enhanced memory formation and the experimental subjects did not get a boost in memory for the emotional section.

• Flashbulb Memories - Where you when????

Emotion Charged Event

Sympathetic Nervous System releases epinephrine

(adrenaline) and norepinephrine (noradrenaline)

Amygdala

Hippocampus into a more alert, activated

state. Something important is happening…

Focus! Focus! Focus!

Memory Consolidation


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