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478 four hours, and five grains of mercury and chalk and of Dover’s powder at bed-time. On the 16th he was better, and the same treatment was continued. On the 18th he required a tonic mixture; after which, con- valescence-was gradually restored. Remarks.—Without requiring many special remarks, the cases will speak for themselves. I would only add, that it is shown in Case 2, that the abstraction of blood during the first stage, in cases of this sort-as was proposed in the late unfortunate occurrences-in the Kenilworth-street sewer, is likely to be followed by injurious, and perhaps fatal conse- quences. The treatment most appropriate in cases where re- spiration is suspended, seems to be the introduction, by arti- ficial means, of atmospheric air into the lungs, seconded by treatment generally pursued, where collapse has occurred. West Bromwich, Nov. 27, 1849. Hospital Reports. MIDDLESEX HOSPITAL. Reported by W. B. CLAPHAM, Esq, House-surgeon. Two Cases of Laryngotomy. CASE 1.-James D-,aged thirty, was admitted into Handel ward, under Mr. Shaw, Jan. 7th, 1850, with an abscess on the left side of the vertebral column, opposite to about the sixth or seventh dorsal vertebras, supposed to be connected with caries ’, of one of those bones, or the contiguous ribs, but of which no evidence could be obtained, either by probing or external examination. Tolerably healthy pus was oozing from it at the time of his admission, from one or two small openings which had been made iri its most superficial part by his sur- geon in the country. On Tuesday, Jan. 22nd, he first complained to me of slight soreness and smarting of the throat, which he attributed to his medicine. (He was taking, liquor potassœ, twenty minims; tincture of hyoscyamus, half a drachm; compound mixture of gentian, an ounce and a half,—three times a day.) There was nothing unusual in his appearance; he had no difficulty of breathing or of deglutition, excepting the medicine, which, he said, gave him pain in swallowing. On questioning him the next day, the soreness was still persistent; and on exa- mining his throat, nothing could be discovered to account for it. There was slight redness of the velum and arches of the palate, but the tonsils and posterior part of the pharynx were natural. He was directed to wash the back of his mouth, three or four times a day, with alum gargle. He made no further complaints until the following evening, when he ob- served to the nurse that he thought " the gargle did not reach the sore part, as it was deeper down;" but he swallowed his tea with ease. I saw nothing more of him until half-past six the next morning, when the sister called me to him, to say that he was choking. I went to the ward immediately, and found him struggling for breath, propped up in bed, scarcely able to articulate, with stridulous breathing, which accompanied both expiration and inspiration, the air being drawn in by gasps through the opened mouth. On looking into the throat, nothing unusual presented itself, excepting the slight redness above alluded to. On sweeping the finger round the pharynx, the glottis felt unusually large, as if swollen from oedema. He evinced pain on handling the larynx externally, and it appeared somewhat enlarged, although there was no general swelling of the parts about the neck. His lips were dry and livid, and his face congested, evidently from imperfect oxy- genization of the blood; and his pulse was quick and small. According to the night-nurse, his breathing first became more difficult between two and three A.M.; but no distress or urgent symptoms manifested themselves until about six. At five o’clock he swallowed half a pint of milk with tolerable facility. He expectorated nothing, but a watery fluid flowed from his mouth-no doubt saliva-and he made several attempts to vomit. Fifteen leeches were applied to the throat, and the bleeding encouraged by a warm linseed poultice, covered with oil-silk; and he was ordered to take half a grain of tartrate of antimony every half-hour. The nature of the case now became evident-one of acute laryngitis, with oedema glottidis; and suspecting what it must soon come to, I prepared a trocar and canula ready for the emergency, which was not long in showing itself; for soon after eight the nurse came running to me, to say that he was choked. I ran up to the ward, taking Dr. Corfe with me, whom I met in the passage. The man was then apparently dead, for respiration had ceased, and the sister exclaimed, " It is too late, sir; he is gone." His pulse was still beating. I’ directed her to take the poultice off immediately, and at once- made an incision down to the crico-thyroid membrane, and thrust in the trocar, which was withdrawn, leaving in the canula. No voluntary respiration followed, although we blew a current of cold air on his face &c. The mouth was applied to the tube, and the lungs inflated, the air being gently pumped out again by pressing on the chest. After repeating this once more, he expelled it himself, and by degrees began to breathe naturally. The change in his countenance was perceptible- almost instantaneously; his face, which was before pale and livid, became perceptibly red; his lips regained their usual colour; and he breathed with tolerable ease, interrupted only by an occasional paroxysm of coughing, which expelled some bloody mucus through the tube. Some slight cerebral dis- turbance followed, in the space of a few minutes, manifested by the convulsive struggles of his body, his snapping at us with his teeth and hands, and by the dilatation of his pupils; but this passed off in from five to ten minutes, and he became collected. The tube was now fastened in, and a nurse directed to sit constantly by him, to keep it free; and he was to take, tartrate of antimony, a quarter of a grain; chloride of mer- cury, two grains,-in powder, every four hours. The operation was extremely simple, performed with ease, and unattended with bleeding. During the day he remained quiet, breathing tranquilly and naturally through the tube; lie experienced great difficulty in swallowing, and evinced extreme tenderness of the larynx on touching it; his skin was perspiring freely; his pulse 120, but not jerking; he vomited each powder about ten minutes after taking them. Jan. 26th.-Has passed a sleepless night, and his counte nance is more pallid and anxious than yesterday; he has been sweating very profusely, and his pulse is 130, and more feeble. The tube was changed about ten A.M. He coughed more mucus through it, and attempts at swallowing brought on spasmodic attacks of coughing. He was perfectly sensible, and not so much tenderness of the larynx as yesterday. On closing the tube with the finger, little or no air found its way to the lungs through the mouth. Speech was consequently lost. Ordered, mercury with chalk, ten grains; chloride of mercury, one grain, every six hours. Towards night he became more distressed and sinking, and his countenance livid and sunken; he breathed extremely quick, and a thin, watery, frothy sputa, came through the canula at each expira- tion. On applying the stethoscope to the chest, large crepi- tation was heard over the whole of its surface anteriorly, with small crepitation at the base of the left lung, indicating the presence of general bronchitis, mixed up with pneumonia, from which he was evidently sinking. Ordered, a blister to the chest; ice in mouth. He died at five A.M., forty-eight hours after the operation. Post-mortem examination, fifty hours afterwards.—On reflect- ing the skin and platysma from off the neck on either side, a deposition of purulent matter was seen in the cellular tissue, behind the sterno-mastoid on the left side, and extending beneath its posterior border. An extensive purulent deposit- of jelly-like pus was seated beneath the post-pharyngeal fascia, extending upwards beyond the level of the tonsils on either side and downwards as far as the middle of the oesophagus, the mucous membrane of which was reddened, and its upper part in a sloughy state. The tonsils were slightly enlarged, but contained no purulent matter. The mucous membrane uniting the epiglottis to the root of the tongue and arches of the palate was tumefied. The epiglottis itself was cede- matous, converted into a slough, its posterior free margin having a red, velvety edge. On opening the larynx its inner surface was throughout in a sloughy state, isolated patches of which occupied the posterior part of the trachea to within an inch of its bifurcation, slight attempts having been made to throw one or two of them off. Its mucous membrane was considerably reddened, but that of the bronchial tubes in- tensely injected, and filled with a thick, sanious, muco-puru lent fluid, containing no air-bubbles. A thin layer of concrete pus was likewise observed at the roots of both lungs, occu- pying a large extent of surface, and situated immediately beneath their serous covering. The pleurae were both in- flamed, and their cavities filled with fluid, but there were no adhesions. The lungs were greatly engorged and congested, but slightly crepitant, soft and friable in texture, and in- elastic, containing scattered patches of lobular pneumonia, these pieces being quite impermeable, and sinking in water. The heart was hypertrophied and flabby, its external surface , covered with large patches of recent lymph, jelly-like masses
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Page 1: MIDDLESEX HOSPITAL

478

four hours, and five grains of mercury and chalk and ofDover’s powder at bed-time.On the 16th he was better, and the same treatment was

continued.On the 18th he required a tonic mixture; after which, con-

valescence-was gradually restored.Remarks.—Without requiring many special remarks, the

cases will speak for themselves. I would only add, that it isshown in Case 2, that the abstraction of blood during thefirst stage, in cases of this sort-as was proposed in the lateunfortunate occurrences-in the Kenilworth-street sewer, islikely to be followed by injurious, and perhaps fatal conse-quences. The treatment most appropriate in cases where re-spiration is suspended, seems to be the introduction, by arti-ficial means, of atmospheric air into the lungs, seconded bytreatment generally pursued, where collapse has occurred.West Bromwich, Nov. 27, 1849.

Hospital Reports.MIDDLESEX HOSPITAL.

Reported by W. B. CLAPHAM, Esq, House-surgeon.

Two Cases of Laryngotomy.CASE 1.-James D-,aged thirty, was admitted into Handel

ward, under Mr. Shaw, Jan. 7th, 1850, with an abscess on theleft side of the vertebral column, opposite to about the sixth orseventh dorsal vertebras, supposed to be connected with caries ’,of one of those bones, or the contiguous ribs, but of which noevidence could be obtained, either by probing or externalexamination. Tolerably healthy pus was oozing from it atthe time of his admission, from one or two small openingswhich had been made iri its most superficial part by his sur-geon in the country.On Tuesday, Jan. 22nd, he first complained to me of slight

soreness and smarting of the throat, which he attributed tohis medicine. (He was taking, liquor potassœ, twenty minims;tincture of hyoscyamus, half a drachm; compound mixture ofgentian, an ounce and a half,—three times a day.) Therewas nothing unusual in his appearance; he had no difficultyof breathing or of deglutition, excepting the medicine, which,he said, gave him pain in swallowing. On questioning himthe next day, the soreness was still persistent; and on exa-mining his throat, nothing could be discovered to account forit. There was slight redness of the velum and arches of thepalate, but the tonsils and posterior part of the pharynx werenatural. He was directed to wash the back of his mouth,three or four times a day, with alum gargle. He made nofurther complaints until the following evening, when he ob-served to the nurse that he thought " the gargle did notreach the sore part, as it was deeper down;" but he swallowedhis tea with ease.

I saw nothing more of him until half-past six the nextmorning, when the sister called me to him, to say that he waschoking. I went to the ward immediately, and found himstruggling for breath, propped up in bed, scarcely able toarticulate, with stridulous breathing, which accompanied bothexpiration and inspiration, the air being drawn in by gaspsthrough the opened mouth. On looking into the throat,nothing unusual presented itself, excepting the slight rednessabove alluded to. On sweeping the finger round the pharynx,the glottis felt unusually large, as if swollen from oedema.He evinced pain on handling the larynx externally, and itappeared somewhat enlarged, although there was no generalswelling of the parts about the neck. His lips were dry andlivid, and his face congested, evidently from imperfect oxy-genization of the blood; and his pulse was quick and small.According to the night-nurse, his breathing first became moredifficult between two and three A.M.; but no distress or urgentsymptoms manifested themselves until about six. At fiveo’clock he swallowed half a pint of milk with tolerable facility.He expectorated nothing, but a watery fluid flowed from hismouth-no doubt saliva-and he made several attempts tovomit. Fifteen leeches were applied to the throat, and thebleeding encouraged by a warm linseed poultice, covered withoil-silk; and he was ordered to take half a grain of tartrate ofantimony every half-hour.The nature of the case now became evident-one of acute

laryngitis, with oedema glottidis; and suspecting what it mustsoon come to, I prepared a trocar and canula ready for theemergency, which was not long in showing itself; for soonafter eight the nurse came running to me, to say that he waschoked. I ran up to the ward, taking Dr. Corfe with me,

whom I met in the passage. The man was then apparentlydead, for respiration had ceased, and the sister exclaimed, " Itis too late, sir; he is gone." His pulse was still beating. I’directed her to take the poultice off immediately, and at once-made an incision down to the crico-thyroid membrane, andthrust in the trocar, which was withdrawn, leaving in thecanula. No voluntary respiration followed, although we blewa current of cold air on his face &c. The mouth was appliedto the tube, and the lungs inflated, the air being gently pumpedout again by pressing on the chest. After repeating this oncemore, he expelled it himself, and by degrees began to breathenaturally. The change in his countenance was perceptible-almost instantaneously; his face, which was before pale andlivid, became perceptibly red; his lips regained their usualcolour; and he breathed with tolerable ease, interrupted onlyby an occasional paroxysm of coughing, which expelled somebloody mucus through the tube. Some slight cerebral dis-turbance followed, in the space of a few minutes, manifestedby the convulsive struggles of his body, his snapping at uswith his teeth and hands, and by the dilatation of his pupils;but this passed off in from five to ten minutes, and he becamecollected. The tube was now fastened in, and a nurse directedto sit constantly by him, to keep it free; and he was to take,tartrate of antimony, a quarter of a grain; chloride of mer-cury, two grains,-in powder, every four hours. The operationwas extremely simple, performed with ease, and unattendedwith bleeding. During the day he remained quiet, breathingtranquilly and naturally through the tube; lie experiencedgreat difficulty in swallowing, and evinced extreme tendernessof the larynx on touching it; his skin was perspiring freely;his pulse 120, but not jerking; he vomited each powder aboutten minutes after taking them.

Jan. 26th.-Has passed a sleepless night, and his countenance is more pallid and anxious than yesterday; he has beensweating very profusely, and his pulse is 130, and more feeble.The tube was changed about ten A.M. He coughed moremucus through it, and attempts at swallowing brought onspasmodic attacks of coughing. He was perfectly sensible,and not so much tenderness of the larynx as yesterday. Onclosing the tube with the finger, little or no air found its wayto the lungs through the mouth. Speech was consequentlylost. Ordered, mercury with chalk, ten grains; chloride ofmercury, one grain, every six hours. Towards night hebecame more distressed and sinking, and his countenancelivid and sunken; he breathed extremely quick, and a thin,watery, frothy sputa, came through the canula at each expira-tion. On applying the stethoscope to the chest, large crepi-tation was heard over the whole of its surface anteriorly, withsmall crepitation at the base of the left lung, indicating thepresence of general bronchitis, mixed up with pneumonia,from which he was evidently sinking. Ordered, a blister tothe chest; ice in mouth. He died at five A.M., forty-eighthours after the operation.

Post-mortem examination, fifty hours afterwards.—On reflect-ing the skin and platysma from off the neck on either side, adeposition of purulent matter was seen in the cellular tissue,behind the sterno-mastoid on the left side, and extendingbeneath its posterior border. An extensive purulent deposit-of jelly-like pus was seated beneath the post-pharyngeal fascia,extending upwards beyond the level of the tonsils on eitherside and downwards as far as the middle of the oesophagus,the mucous membrane of which was reddened, and its upperpart in a sloughy state. The tonsils were slightly enlarged,but contained no purulent matter. The mucous membraneuniting the epiglottis to the root of the tongue and archesof the palate was tumefied. The epiglottis itself was cede-matous, converted into a slough, its posterior free marginhaving a red, velvety edge. On opening the larynx its innersurface was throughout in a sloughy state, isolated patches ofwhich occupied the posterior part of the trachea to within aninch of its bifurcation, slight attempts having been made tothrow one or two of them off. Its mucous membrane wasconsiderably reddened, but that of the bronchial tubes in-tensely injected, and filled with a thick, sanious, muco-purulent fluid, containing no air-bubbles. A thin layer of concretepus was likewise observed at the roots of both lungs, occu-pying a large extent of surface, and situated immediatelybeneath their serous covering. The pleurae were both in-flamed, and their cavities filled with fluid, but there were no

adhesions. The lungs were greatly engorged and congested,but slightly crepitant, soft and friable in texture, and in-elastic, containing scattered patches of lobular pneumonia,these pieces being quite impermeable, and sinking in water.The heart was hypertrophied and flabby, its external surface

, covered with large patches of recent lymph, jelly-like masses

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of which were interposed between the heart and pericardial sac, adhering loosely to either. The pericardium contained,in addition, some three ounces of turbid fluid. No traces of

phlebitis could be discovered. The abdominal viscera werehealthy.

CASE 2.-James B-, aged twenty-five, our laboratoryman, while engaged in poisoning a dog, scratched the backpart of the second finger of his right hand, having, since theprevalence of the late epidemic, been in a bad state of health,from a sharp attack of diarrhoea, which came upon him at thatperiod. Upon this scratch supervened an attack of inflamedabsorbents of the right arm, from which he was just recover-ing, when sore-throat, inflamed tonsils, and a hard, deep, tenseswelling appeared on the right side of the neck, just belowthe angle of the jaw. He went into the country for a fewdays; but finding that he got no better, returned to us on theFriday, and was admitted into Cambridge ward.On the following Monday he had been so far relieved by

leeches, salines, and scarifying the tonsils, that he swallowedwith perfect ease, but said he was worse, and should die. Atfour P.M. his breathing was uneasy, and more leeches wereapplied to the swelling of the neck, but without any benefit,for at five P.M. the sister of the ward came to sav that he was

dying from choking. Mr. Dixon ran up stairs, and immedi-ately sent for me to bring a trachea-tube and trocar, and wewere about to perform laryngotomy, when Dr. Corfe came in,just as he was gasping his last breath. I pushed in the trocar,after making a small incision over the crico-thyroid mem-brane. Air rushed into the canula, but no natural respirationfollowed. Mr. Dixon breathed into the tube four or sixtimes, pumping it out again by pressing upon the chest.After this the respiratory muscles gradually acted, six, eight,twelve, and twenty in the minute. Epileptic fits now followed,to a frightful extent, for which he was bled pretty freely, withgreat relief; but they afterwards came on again, and continuedall night., every quarter or half hour. He became, however,quite sensible on the Tuesday night, and on Wednesdaymorning was as rational as ever; but towards the eveninghis breathing became more hurried, his pulse more quick andfeeble, and his teeth were constantly grinding together, butthe tube was perfectly free.At three A.M., on Thursday, Dr. Corfe was called to him.

He was then sinking rapidly, from clogged bronchi and gorgedlungs, and died at nine, six days after admission, and two anda half after the operation.Post-mortem examii?atio2z, twenty-four hours afterwards.—The

whole of the cellular tissue of the right side of the necktumefied, thickened, and indurated to a somewhat cartilagi-nous consistency, as well as considerably infiltrated with pus,more especially about the middle course of the sterno-mastoidmuscle. Acute inflammation of the larynx, and the wholemucous membrane in a sloughy state, ash-coloured. Rightcorda vocalis thickened, and in its centre purulent deposit.Acute bronchitis, and pneumonia of the right lung in its twolower lobes. No inflamed vein in the right arm.

Reviews and Notices.

Statistics of Cholera. By Assistant-Surgeon EDWARD BALFOUR,of the Madras Army. Pamphlet, 8vo, pp. 70. Madras:Pharoah & Co. 1849.

The Cholera- What has it tauglat us ? By WILLIAM J. COX,M.R.C.S. Pamphlet, 8vo, pp. 26. London: Renshaw.1850.

Short Essay on the invariably Successful Treatment of Cholerawith Water. By C. C. SCHIEFERDECKER, M.D. Pamphlet,8vo, pp. 32. Philadelphia: Moore. 1849.

IF every pamphlet which appears on cholera added somethingto our knowledge on the subject, it would soon be one of thebest-understood diseases. Although such is far from beingthe case, we yet believe that recent contributions have, onthe whole, thrown additional light on the nature of cholera.A merely statistical inquiry is not, of itself, calculated to leadto the discovery of either the cause or the best treatment ofa disease, yet it may furnish materials which, when combinedwith the observation of individual facts, may lead to suchdiscovery. As a contribution to the statistics of cholera, thepamphlet of Mr. Balfour is the most important work that hasappeared for a long time. There are epidemics of opinion as

well as of disease. For some years it has been the prevailingopinion amongst medical men, in India, that cholera is in 00way contagious or infectious; and Mr. Balfour seems to con-sider this to be a settled question, although some of the cir-cumstances which he relates seem to indicate contagion, andat all events could be best explained by admitting it. Take,for instance, the following passage, where, after treating ofthe cessation of cholera that often results, on moving a regi-ment to new quarters, the author says,-

" When the change is not followed by success, it is doubtfulwhether the failure be owing to the agent that gives rise tothe epidemic being so generally diffused, that no neighbouringground can be taken up free from its influence; or whether itbe that the men having once been exposed to the morbificcause, the continuance of the disease is only the slow deve-lopment of its action, though the former is probably the truereason. There are instances where corps on the line of marchhave been attacked by cholera, and carried it along with themfor weeks, and even months, through districts enjoying a per-fect freedom from the dreaded scourge; and a healthy regi-ment will pass another on the march, at the time they aredaily losing numbers of their men and followers, and will behalted for many succeeding days on the ground, dotted overwith the newly-disturbed earth, where the corps which hadjust vacated it had buried their dead, and though moving inthe same route the sickly corps had just come over, thehealthy regiment continues its journey, free from its attacks."- p. 58.

It appears to us that the above circumstances cannot be

explained by supposing that the epidemic agent is generallydiffused. They seem to point to the transmission of the dis-ease from one patient to another, although the manner inwhich it is transmitted is probably unknown.The pamphlet of Mr. Cox consists chiefly, as he states in

his preface, of some contributions by him to the pages of thisjournal. It contains a table of ninety cases of cholera attendedby the author, and treated in various ways; fifty-five of themhaving been treated by calomel on Dr. Ayre’s system. The mor-tality amongst the fifty-five so treated was only thirteen, whilstamongst the remaining thirty-five, treated by other methods,there were eighteen deaths. ’Ve observe, however, that thecases treated on Dr. Ayre’s plan appear, nearly all of them, tohave occurred after the others, and must therefore make theremark, that the cholera in many places, both in the recentand former epidemic, was more fatal on its first outbreak, andmuch less so towards the end; so that practitioners have oftenthought that they had found a remedy in the treatment lastpursued.

Dr. Schieferdecker appears to be a German hydropathist,who has gone to America, and is attempting to make a profitout of the gullibility of " Brother Jonathan." The extent ofhis own experience of cholera, as far as it is related, is, thathe saw three of his friends treated successfully with water,whilst suffering from the malady at Halle, in 1832. He says,that if any one does not get well under the water treatment,it is because it is not applied in time and in a sensible manner.He gives a table’of cases alleged to have been treated by"the immortal V. Priessnitz" and others, and in the columnfor deaths there is always the word " none." He adds,-

" This table could be continued to any extent, inasmuch asevery time when cold water was applied in time and in a.

sensible manner in a cholera case, the patient was saved."-p. 27.On this principle, we believe that any treatment could be

shown to be an infallible cure of cholera, and a table mightbe constructed and " continued to any extent" by omittingthe fatal cases.

THE YELLOW FEVER.—This terrible scourge ismaking great ravages at Bahia, (Brazils.) All the sick whowere brought to the British Hospital have died. Many of thepatients were attended on board the vessels, for want of roomin the various hospitals of the town.


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