National Naval Medical Center (NNMC)Directorate for Professional Education

Clinical Investigations Department

How to start research at NNMC

April, 2011

Marina Borovok, PhDHead of Research Education,Clinical Investigations Department, NNMC

"There is always a better way to do it.

Find it !!!"

— Thomas A. Edison

How we can find “a better way to do it”?

Only through the best available scientific knowledge,

and research-based decision making.

Presentation OutlineI. How to start research at NNMC:

- Obtaining a DKO/AKO account,

- Registering with IRBNet,

- Completion of CITI training,

- Research topic selection,

- Research protocol/publication preparation,

- Research protocol/publication submission.

II. NNMC Research Resources : - Responsible Conduct of Research Service (RCRS),

- Darnall Biomedical Learning Resource Center (DBLRC),

- Research Protocol/Publication Help,

- Education/Mentoring Resources,

- ICEBERG;

Research Cue Card

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I. How to start research at NNMC

Step 1: Obtaining a DKO/AKO account

at https://www.us.army.mil/suite/page/596540

(DMRN page on DKO/AKO website).

Cue Card Reference:

Step 1: Obtaining a DKO/AKO account(cont.)

Login using your AKO/DKO username and password

Step 1: Obtaining a DKO/AKO account(cont.)

You are at the DMRN site at https://www.us.army.mil/suite/page/596540

Click on the IRBNet Entry button

Step 1: Obtaining a DKO/AKO account(cont.)

Instructions are at the RCRS websitehttps://nnmcintra/SiteDirectory/RCRS/IRBNet/Forms/AllItems.aspx.

Questions? Please contact Mr. Luis Calvo at Luis.Calvo@med.navy.mil, 301 295-2269.

Step 2: Registering with IRBNet, e-portal for publications and protocol submission.

Cue Card Reference:

Instructions are at the RCRS websitehttps://nnmcintra/SiteDirectory/RCRS/IRBNet/Forms/AllItems.aspx.

Step 2: Registering with IRBNet, e-portal

for publications and protocol submission (cont.)

Questions?

Please contact Mr. Luis Calvo

at Luis.Calvo@med.navy.mil,

301 295-2269.

Step 3: Completion of CITI trainingCue Card Reference:

Principal Investigators, Associate Investigators, Research Staff, as well as anyone coming into contact with Human Subjects or involved with the consent process or study design are required to complete this course.

Step 3: Completion of CITI training

The course is available at https://www.citiprogram.org

Completion of CITI training

First Time Users need to register athttps://www.citiprogram.org/enroll/courseregistration1.asp?

language=english.

Questions?

Please contact Mrs. Toby Perkins

at Toby.Perkins@med.navy.mil,

301 319-8994.

Now you are done with the registrations and training.

What is next?

Next steps: 4-5The entire research writing process can be divided

into easily manageable and clear steps:

STEP 4: Develop a Research Question

Select a topic

Find Sources to support your ideas

STEP 5: Research Protocol Preparation:

Literature Review

Start Writing

Statistical Analysis

Complete Detailed Study Protocol

STEP 6: Submit your proposal via

Step 4: Research topic selection

Cue Card Reference:

In order to do that you need to consult with your Department Chair/Supervisor/Mentor.

Need help to choose your Mentor?

Please contact Dr. Marina Borovok

at marina.borovok@med.navy.mil, 301 295-2876.

Good research question: could the "FINER" criteria be applied to it?

F- Feasible.  Is the question answerable?  Do you have access to all the materials you will need to do the study? 

Do you have access to enough subjects?  Will you have enough time and money?  Do you have the expertise to do this study or can you collaborate with

someone who does?

I- Interesting.  The question has to be interesting to the investigator, but should also be interesting to others.

N- Novel.  Has this study been done before?  Does it add to the current body of medical knowledge?

E- Ethical.  Risk/benefit ratio? Can the study be done with a minimal risk?  Will an IRB approve the study?

R- Relevant.  Will it further medical science?  Will the results change clinical practice, health policy or point towards further avenues of research?

If your question fails on any one of these 5 criteria, it is probably not worth putting much effort into.Additional reading:http://familymed.uthscsa.edu/facultydevelopment/elearning/ResearchQuestions.swfAppendix 3

Step 5: Research Protocol Preparation

Literature Search help:Mr. Fredric Simms, MLSMedical Researcher,Phone: (301) 295-0080E-mail address: James.Simms@med.navy.mil Bldg. 1, 1st floor, rm 1633

Ms. Kimberly D. Adams, M.A., M.S., M.L.S.

Reference Librarian at WRAMC

Phone: (202) 782-6547

E-mail address: kimberly.adams3@amedd.army.mil

Statistical Data Analysis help:Dr. Francois O. TuamokumoMathematical Statistician Phone: (301) 319 8788Email: francois.tuamokumo@med.navy.mil Bldg. 1, 4th floor, rm 4342

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Cue Card Reference:

Step 6: Protocol submission via

Cue Card Reference:

Submission instructions are available on the IRBNet portal, under Forms and Templates.

Questions?

Please contact RCRS at

NNMC-ResearchQuestions@med.navy.mil,

301 295-2275.

Next steps are: SRP,IRB approval

These steps will be successful if you worked on the Research Protocol with help of the NNMC specialists (Step 5) 

IMPORTANT TO REMEMBER !!!

Cue Card Reference: 

You may not begin your research until

you have received

an IRB Approval and Approval Letter

from the Commander, NNMC.

 

The Walter Reed Army Medical Center (WRAMC)

The Walter Reed Army Medical Center (WRAMC) processes are very similar to NNMC, since both centers follow most of the same regulations.

The National Capital Region Military Medical Centers POCs:

National Naval Medical Center (NNMC) ,

Responsible Conduct of Research Service Sheila Gaines 301-295-6512

 

Walter Reed Army Medical Center (WRAMC),

Department of Clinical Investigation Verna Parchment 202-782-7828

 

Malcolm Grow Medical Center (MGMC),

IRB Office Cheryl James 240-857-8216

 

The Uniformed Services University (USU),

Research Office Maggie Pickerel 301-295-0819

Questions?

II. NNMC Research Resources Research Integrity Resources

Responsible Conduct of Research Service (RCRS) – HUMAN SUBJECT PROTECTION

Darnall Biomedical Learning Resource Center (DBLRC)

Research Protocol/Publication Help,

Education/Mentoring Resources,

ICEBERG;

Research Integrity Resources It is a policy of Navy Medicine that all personnel will uphold highest principles of ethics

promoting research integrity and the responsible conduct of research (RCR).

RCR RESOURCES (hard copies and web links):

TEXT (available at RCRS)

On Being A Scientist, National Academy of Sciences Committee on the Conduct of Science, 3rd Ed.,

Also available on the web at http://www.nap.edu/openbook.php?isbn=0309119707

 

DVD “THE LAB” (available at RCRS,)

an interactive educational DVD has been developed by ORI for education regarding research misconduct.

Also available on the web at http://ori.dhhs.gov/TheLab,

RCRS site at https://nnmcintra/SiteDirectory/RCRS/default.aspx (under the RCRS links),

ANTI-PLAGIARISM SOFTWARE TURNITIN (web-based,

http://turnitin.com/static/index.php)

Free access available to the NNMC researchers.

 WEB RESOURCES PROVIDED ON THE RCRS WEBSITE (INTRANET) at:

https://nnmcintra/SiteDirectory/RCRS/default.aspx (under RCRS Links):

RESEARCH INTEGRITY

THE LAB: Interactive Movie on Research Misconduct

AVOID PLAGIARISM: 26 Guidelines at a glance

Research Ethics Resources provided by The Navy Medicine Institute

On Being a Scientist: A Guide to Responsible Conduct in Research: Third Edition (2009)

HUMAN SUBJECT PROTECTION

Cue Card Reference:

RCRS

RCRS information

Bldg. 1, 4th floor, room 4394

RCRS Intranet https://nnmcintra/SiteDirectory/RCRS/default.aspx

RCRS Internet http://www.bethesda.med.navy.mil/professional/research/Responsible_Conduct/index.aspx

Questions: 301 295-2275

NNMC-ResearchQuestions@med.navy.mil

Head of the Clinical Investigation Department:

CAPT Jeffrey Lenert, MD

Jeffrey.Lenert@med.navy.mil

Darnall Biomedical Learning Resource Center (DBLRC)

Cue Card Reference:

Bldg. 1, 3rd floor, room 3458

Intranet

https://nnmcintra/SiteDirectory/STITT/default.aspx

Internet

http://www.bethesda.med.navy.mil/professional/stitt_library

Questions: 301 295-1184

NNMC-DBLRC@med.navy.mil

Darnall Biomedical Learning Resource Center (DBLRC)

Darnall Biomedical Learning Resource Center (DBLRC)

Bldg. 1, 3 rd floor, room 3458• Hours Main Number

Monday-Thursday   0700-1730Friday                    0700-1600 301-295-1184

• After Hours Access is availableContact Ann Holman at Ann.Holman@med.navy.mil, 

or visit the Circulation Desk to sign up for an access account, and we'll contact you when your card is ready. 

Library Access Card

Research Protocol/Publication HelpLiterature Search:

Comprehensive DB specialist: Mr. Fredric Simms, MLS

James.Simms@med.navy.mil 301 295-0080

Ms. Kimberly D. Adams, M.A., M.S., M.L.S.

Reference Librarian at WRAMC

Phone: (202) 782-6547

E-mail address: kimberly.adams3@amedd.army.mil

Statistical Data Analysis:

Mathematical Statistician: Francois O. Tuamokumo, PhD

francois.tuamokumo@med.navy.mil 301 319-8788

Cue Card Reference:

 

Education/Mentoring ResourcesResearch Course: 9 CME/CE, 2 days (0630-1100); 2011:

3/21-22, 5/2-3, 7/7-8, 9/22-23, 11/8-9

Hands-on Research Preparation Course: April-December, 2011, Th., noon-1400.

PubMed Search Course: December 10, 2010

Head of Research Education: Marina Borovok, PhD

marina.borovok@med.navy.mil 301 295-2876

Cue Card Reference:

Interdepartmental Collaborative BethesdaResearch Group

http://nnmcresearch.wikispaces.com/

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ICEBERG Mission

Help National Naval Medical Center

to become

a premier research organization

in the Department of Defense.

Questions?

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Thank You!

My Contact Information:Marina Borovok, PhDHead of Research EducationClinical Investigation DepartmentProfessional Education DirectorateNational Naval Medical Center8901 Wisconsin Avenue,Bldg. 1, Rm. 4372,Bethesda, MD 20889Phone: 301-295-2876Fax: 301-295-1490E-mail: marina.borovok@med.navy.mil