NATIONAL ONCOLOGICAL HOSPITALНАЦИОНАЛНА БОЛНИЦА ПО ОНКОЛОГИЯ
BULGARIAN NATIONAL CANCER REGISTRYБЪЛГАРСКИ НАЦИОНАЛЕН РАКОВ РЕГИСТЪР
CANCER INCIDENCE IN BULGARIA 2006ЗАБОЛЯЕМОСТ ОТ РАК В БЪЛГАРИЯ, 2006
Volume XVII2008
РедакториЗдрaвка Валерианова
Mирчо Вуков Надя Димитрова
EditorsZdravka ValerianovaMircho VukovNadya Dimitrova
Издателство “АВИС-24” ООД Publisher “AVIS-24” Ltd.
БЪЛГАРСКИ НАЦИОНАЛЕН РАКОВ РЕГИСТЪР
ПЕРСОНАЛдоц. д-р Здравка Г. Валерианова, дм ръководител регистърд-р Надя Е. ДимитроваМария С. ДановаМинка М. НеноваТинка П. КуневаЙовка К. ПетковаМинка Р. ЙордановаЛиляна Н. УзуноваТеодора Й. ГрозеваДимитър Хр. ХристовТраян Й. Атанасов
ЗА ИНФОРМАЦИЯЗдравка Г. Валерианова
БЪЛГАРСКИ НАЦИОНАЛЕН РАКОВ РЕГИСТЪР“Пловдивско поле” 61756 СОФИЯ, БЪЛГАРИЯтел/факс: 02/ 8706258, тел: 8076 335факс: 02/ 8720651е-mail: [email protected] web site: http://www.onco-bg.com
BULGARIAN NATIONAL CANCER REGISTRY
STAFFZdravka G. Valerianova, MD, PhDHead of BNCRNadya Е. Dimitrova, MDMaria S. DanovaMinka M. NenovaTinka P. KunevaIovka K. PetkovaMinka R. YordanovaLilyana N. UzunovaTeodora Y. GrozevaDimitar H. HristovTrayan Y. Atanasov
FOR INFORMATIONZdravka G. Valerianova
BULGARIAN NATIONAL CANCER REGISTRY6, Plovdivsko pole Str.1756 SOFIA, BULGARIAtel/fax: +359 2/ 8706258, 8076 335fax: +359 2/ 8720651е-mail: [email protected] web site: http://www.onco-bg.com
6
REPUBLIC OF BULGARIA
Republic of Bulgaria is situated in South-Eastern Europe, on the Balkan Peninsula, between 44°13’ and 41°14’ N (northern latitude) and 28°36’ and 20°21’ E (eastern longitude). Its total area is 110 911.5 sq. km. Bulgaria is at the border of line between the temperate and Mediterranean climatic areas. In its Northern part, the climate is temperate continental, whereas the southern part is infl uenced by the Mediterranean Sea. The population of Bulgaria is 7 699 020 (2006). The country is divided into 28 administrative districts and about 70% of the population lives in urban areas. The predominant religion in the country is Eastern Orthodox (85% of the population), followed by Muslims (13%), and Catholics (1%). A specialized cancer network was founded in Bulgaria in 1952. It consists of 13 Regional Oncological Centers (dispensaries) and a National Oncological Hospital in Sofi a. The Regional Oncological Registries are part of the structure of each Regional Oncological Center, and the Bulgarian National Cancer Registry (BNCR) – of the National Oncological Hospital. In the country exists a compulsory registration of malignant neoplasm, regulated by a Ministry of Health Instruction № 858/ 05.03.1964, a Ministry of Health Order № RD-09-451/ 29.06.1990 and a Ministry of Health Regulation № 34/ 2005.Every physician/medical worker is required to send a “rapid notifi cation” to the Regional Oncological Center for each newly diagnosed cancer case, for a person suspected of having cancer or for those dying from a malignant neoplasm, and since 1975 for carcinoma in situ, as well, by the patient’s permanent residence.The BNCR uses active and passive methods of data collection. The personnel of the Regional Oncological Registries periodically visits the regional health facilities, which provide service, as well as actively seek all cases of malignant neoplasm and carcinoma in situ, unknown to the certain registry. Another source of information on cancer patients are death certifi cates. The BNCR receives information from all Regional Oncological Registries around the country. The data are verifi ed for range and completeness, duplication, and consistency between clinical and morphological diagnosis. The most recent update of the rapid notifi cation was introduced in 1992 (Nomenclature № 2 concerning medical forms, serial № 120А of the Ministry of Health). For 1993 the cancer patients have been following up by type of treatment and date of death, as well. In January 2005 the Xth revision of the International Classifi cation of Diseases (ICD) since 1992 was introduced in Bulgaria. All cases of malignant neoplasm dated after 1993 (the initial year of cases identifi cation by person) had to be recoded, according to the new classifi cation requirements. The localization is coded according to the four-digit rubrics for all malignant neoplasm (С00 - С97), carcinoma in situ (D00 - D09) and for D39.0, D42, D43, D45, D46, D47.1, D47.3 which are changed from Borderline to Malignant according to ICD-O, Third edition, 2000. A software product “Oncology - 2005”, has been developed to serve the needs of registration of cancer cases and was implemented throughout the country in all Regional Oncological Centers at the beginning of 2005. The software meets all requirements of “Standards and Guidelines for Cancer Registration in Europe”, IARC Technical Publication № 40, 2003, for coding of certain variables. It also allows additional information for cancer cases to be collected, for example: information for metastases localization; Clark and Breslow for the malignant melanoma of skin; estrogen and progesterone receptors of breast cancer; new information about the type of medical facility, where the initial treatment happened during the fi rst year after cancer diagnoses.The introduction of the new classifi cation required presenting of some data according to the old IXth and the new Xth revision of ICD. The tables about basis of diagnosis and distribution by stage keep the same coding for malignant neoplasm from the old IXth revision, due to the fact that the new ICD happened in 2005. Data is represented according to both, the old and the new classifi cation, in order not to disrupt the tendency of
7
standardized incidence rate by sex, established in 1981. New information for cancer cases sorted by site, sex, morphology and their distribution by age groups and country districts is represented in compliance with the Xth revision. Data about some organizational aspects of cancer control is presented in three consecutive tables. The fi rst table includes the distribution of the newly diagnosed cancer cases by basis of diagnosis. The second includes data by stage according to the cancer site, throughout the country. The last one contains information about the three major cancer sites (breast cancer, cervix uteri cancer and prostate cancer) sorted by country district for which there are no introduced organized population-based screening in the country. In this issue is presented data about the distribution of the new cancer cases of lung, breast, colon, rectum, cervix uteri and prostate by morphological type. Primary site is the topographic site, where the tumour originated. If there are two or more tumors of different histological types and/or localization, they are considered as two cases. When determining the multiple primary cancers the rules of the International Association of Cancer Registries (IACR) are followed.On December the 4th, 1992 a census of the population in Bulgaria was carried out. It was observed that the population has diminished with 500 000 people for the preceding three years mainly due to emigration. Because of that, a recalculation of the incidence rates for 1989, 1990 and 1991 was necessary. When using volumes one and two of “Cancer Incidence in Bulgaria”, one must take into account that the rates have been calculated before the correction of the population. A check of the Unifi ed System for Civil Registration and Administrative Services to the Population – ESGRAON was made for all cancer cases died since 1998 in order to improve the malignant neoplasm registration system in accordance with IARC requirements.Population and mortality data, published in the current issue, is provided by The National Statistical Institute.All records are kept stored according to The Archives Law from 1974 and The Health Law from 2004.The data on malignant neoplasms incidence, as well as the included additional data, is used for epidemiological studies, for public health administering, etc. This information is available to all individuals and institutions interested according to the legislation of the country for data confi dentiality.
8
THE MEAN POPULATION OF BULGARIA BY AGE AND SEX 2006AGE TOTAL MALES FEMALES
00-04 340522 175281 16524105-09 321280 165080 15620010-14 377688 193648 18404015-19 501413 256891 24452220-24 534704 274270 26043425-29 570721 292392 27832930-34 570802 290577 28022535-39 541860 274416 26744440-44 515918 258445 25747345-49 537859 266208 27165150-54 546034 264890 28114455-59 558437 264260 29417760-64 455175 208310 24686565-69 391506 172322 21918470-74 384395 162658 22173775-79 290263 116870 17339380-84 183015 68346 11466985+ 77428 27266 50162ALL AGES 7699020 3732130 3966890
THE MEAN POPULATION OF BULGARIA BY SEX AND DISTRICTS 2006DISTRICT TOTAL MALES FEMALES
BLAGOEVGRAD 331805 162699 169106BOURGAS 418280 203730 214550YAMBOL 145309 71069 74240VARNA 457419 222973 234446DOBRICH 205140 100426 104714VELIKO TURNOVO 282241 135668 146573GABROVO 135135 65152 69983VRATSA 207460 101077 106383VIDIN 116289 56101 60188MONTANA 165416 80140 85276PLEVEN 303330 148179 155151LOVECH 158310 77543 80767PLOVDIV 706991 340527 366464PAZARDJIK 297031 145754 151277SMOLYAN 130371 63208 67163ROUSSE 256075 124178 131897RAZGRAD 138474 67472 71002SILISTRA 133396 65907 67489SOFIA CITY 1234757 586193 648564SOFIA DISTRICT 259179 126879 132300KYUSTENDIL 151753 73768 77985PERNIK 140329 67933 72396STARA ZAGORA 359273 174805 184468SLIVEN 209431 102069 107362HASKOVO 265192 128864 136328KURDJALI 158002 77925 80077SHOUMEN 197869 96039 101830TURGOVISHTE 134763 65852 68911
9
CANCER INCIDENCE IN BULGARIA 2006DISTRIBUTION OF THE NEW CASES BY PRIMARY SITES AND SEX
CODEICD-10 SITE NUMBER
MALES CRUDE
DATA 100 000
% NUMBERFEMALES
CRUDE DATA
100 000
% NUMBERTOTAL
CRUDE DATA
100 000
%
C00-97 ALL SITES 16754 448.9 100.0 15709 396.0 100.0 32463 421.6 100.0C00 LIP 141 3.8 0.9 62 1.6 0.4 203 2.6 0.6C01-02 TONGUE 133 3.6 0.8 34 0.9 0.2 167 2.2 0.5C03-06 MOUTH 108 2.9 0.6 32 0.8 0.2 140 1.8 0.4C07-08 SALIVARY GLANDS 66 1.8 0.4 40 1.0 0.2 106 1.4 0.3C09 TONSIL 74 2.0 0.4 9 0.2 0.1 83 1.1 0.3C10 OTHER OROPHARYNX 45 1.2 0.3 8 0.2 0.1 53 0.7 0.2C11 NASOPHARYNX 46 1.2 0.3 22 0.6 0.1 68 0.9 0.2C12-13 HYPOPHARYNX 65 1.7 0.4 4 0.1 0.0 69 0.9 0.2C14 PHARYNX UNSPECIFIED 7 0.2 0.0 6 0.2 0.0 13 0.2 0.0C15 OESOPHAGUS 169 4.5 1.0 43 1.1 0.3 212 2.8 0.7C16 STOMACH 1061 28.4 6.3 707 17.8 4.5 1768 23.0 5.5C17 SMALL INTESTINE 27 0.7 0.2 20 0.5 0.1 47 0.6 0.1C18 COLON 1315 35.2 7.9 1172 29.5 7.5 2487 32.3 7.7C19-21 RECTUM AND ANUS 1118 30.0 6.7 813 20.5 5.2 1931 25.1 6.0C22 LIVER 432 11.6 2.6 228 5.8 1.4 660 8.6 2.0C23-24 GALLBLADDER AND EXTRAHEPATIC
BILE DUCTS 108 2.9 0.6 165 4.2 1.1 273 3.5 0.8C25 PANCREAS 627 16.8 3.7 445 11.2 2.8 1072 13.9 3.3C30-31 NOSE, SINUSES 36 1.0 0.2 16 0.4 0.1 52 0.7 0.2C32 LARYNX 571 15.3 3.4 36 0.9 0.2 607 7.9 1.9C33-34 TRACHEA, BRONCHUS, LUNG 3077 82.4 18.4 606 15.3 3.9 3683 47.8 11.4C37-38 OTHER THORACIC ORGANS 26 0.7 0.2 15 0.4 0.1 41 0.5 0.1C40-41 BONE 38 1.0 0.2 41 1.0 0.3 79 1.0 0.2C43 MELANOMA OF SKIN 189 5.1 1.1 155 3.9 1.0 344 4.5 1.1C44 OTHER SKIN 1724 46.2 10.3 1531 38.6 9.7 3255 42.3 10.0C45 MESOTHELIOMA 22 0.6 0.1 13 0.3 0.1 35 0.4 0.1C46 KAPOSI’S SARCOMA 6 0.2 0.0 4 0.1 0.0 10 0.1 0.0C47,C49 CONNECTIVE AND SOFT TISSUE 94 2.5 0.6 97 2.4 0.6 191 2.5 0.6C50 BREAST 53 1.4 0.3 3584 90.4 22.8 3637 47.2 11.2C51 VULVA - - - 120 3.0 0.8 120 1.6 0.4C52 VAGINA - - - 30 0.8 0.2 30 0.4 0.1C53 CERVIX UTERI - - - 1208 30.4 7.7 1208 15.7 3.7C54 CORPUS UTERI - - - 1231 31.0 7.8 1231 16.0 3.8C55 UTERUS UNSPECIFIED - - - 44 1.1 0.3 44 0.6 0.1C56 OVARY - - - 837 21.1 5.3 837 10.9 2.6C57 OTHER FEMALE GENITAL ORGANS - - - 25 0.6 0.2 25 0.3 0.1C58 PLACENTA - - - 3 0.1 0.0 3 0.0 0.0C60 PENIS 51 1.4 0.3 - - - 51 0.7 0.2C61 PROSTATE 1459 39.1 8.7 - - - 1459 19.0 4.5C62 TESTIS 194 5.2 1.2 - - - 194 2.5 0.6C63 OTHER MALE GENITAL ORGANS 6 0.2 0.0 - - - 6 0.1 0.0C64 KIDNEY 405 10.8 2.4 221 5.6 1.4 626 8.1 1.9C65 RENAL PELVIS 40 1.1 0.2 9 0.2 0.1 49 0.6 0.2C66 URETER 8 0.2 0.1 8 0.2 0.1 16 0.2 0.0C67 BLADDER 1131 30.3 6.8 317 8.0 2.0 1448 18.8 4.5C68 OTHER URINARY ORGANS 4 0.1 0.0 3 0.1 0.0 7 0.1 0.0C69 EYE 17 0.5 0.1 24 0.6 0.2 41 0.5 0.1C70-72 BRAIN, NERVOUS SYSTEM 380 10.2 2.3 326 8.2 2.1 706 9.2 2.2C73 THYROID GLAND 46 1.2 0.3 217 5.5 1.4 263 3.4 0.8C74 ADRENAL GLAND 18 0.5 0.1 15 0.4 0.1 33 0.4 0.1C75 OTHER ENDOCRINE GLANDS 3 0.1 0.0 3 0.1 0.0 6 0.1 0.0C81 HODGKIN’S DISEASE 89 2.4 0.5 52 1.3 0.3 141 1.8 0.4C82-85, C96 NON-HODGKIN’S LYMPHOMA 266 7.1 1.6 210 5.3 1.3 476 6.2 1.5C88 IMMUNOPROLIFERATIVE DISEASES 5 0.1 0.0 1 0.0 0.0 6 0.1 0.0C90 MULTIPLE MYELOMA 86 2.3 0.5 88 2.2 0.6 174 2.3 0.5C91 LYMPHOID LEUKAEMIA 179 4.8 1.1 117 3.0 0.7 296 3.8 0.9C92 MYELOID LEUKAEMIA 122 3.3 0.7 111 2.8 0.7 233 3.0 0.7C93 MONOCYTIC LEUKAEMIA 2 0.1 0.0 6 0.2 0.0 8 0.1 0.0C94 OTHER LEUKAEMIAS 13 0.4 0.1 7 0.2 0.0 20 0.3 0.1C95 LEUKAEMIA UNSPECIFIED 28 0.8 0.2 26 0.7 0.2 54 0.7 0.2C26,C39, C48, C76, C80
OTHERS AND UNSPECIFIED SITES824 22.1 4.9 542 13.7 3.5 1366 17.7 4.2
C00-97 BUT C44 ALL SITES BUT NON-MELANOMA SKIN 15030 402.7 89.7 14178 357.4 90.3 29208 379.4 90.0D06 NOT INCLUDED ABOVE CA IN SITU OF
CERVIX UTERI - - - 355 9.0 - 355 4.6 -
10
SPEC
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CANC
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IN B
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SHO
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Kyst
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BLAG
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Paza
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Dist
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Bulg
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11
PERCENTAGE DISTRIBUTION OF CANCER INCIDENCE IN FEMALESBULGARIA 2006
PERCENTAGE DISTRIBUTION OF CANCER INCIDENCE IN MALESBULGARIA 2006
LARYNX 3,4 %
BLADDER 6,8 %
RECTUM AND ANUS 6,7 %
STOMACH 6,3 %
COLON 7,9 %
PROSTATE 8,7 %OTHER SKIN 10,3 %
LUNG, TRACHEAAND BRON 18,4 %
PANCREAS 3,7 %
OTHER 27,8 %
LUNG, TRACHEA AND BRON 3,9 %
STOMACH 4,5 %
RECTUM AND ANUS 5,2 %
OVARY ETC. 5,3 %
COLON 7,5 %
CERVIX 7,7 %
CORPUS 7,8 %
OTHER SKIN 9,7 %
BREAST 22,8 %
OTHER 25,6 %
12
AGE-STANDARDIZED AND CRUDE INCIDENCE RATES OF ALL CANCERS IN MALESBULGARIA 1981-2006
AGE-STANDARDIZED AND CRUDE INCIDENCE RATES OF ALL CANCERS IN FEMALESBULGARIA 1981-2006
2006100
150
200
250
300
350
400
450
500
2006100
150
200
250
300
350
400
450
500
13
AGE-SPECIFIC INCIDENCE RATES FOR ALL CANCERS IN MALESBULGARIA, 1981 AND 2006
AGE-SPECIFIC INCIDENCE RATES FOR ALL CANCERS IN FEMALESBULGARIA, 1981 AND 2006
2006
2006
0
300
600
900
1200
1500
1800
14
AGE-STANDARDIZED INCIDENCE RATES (WORLD STANDARD) OF THE MOST COMMON CANCERS IN MALESBULGARIA 1981-2006
AGE-STANDARDIZED INCIDENCE RATES (WORLD STANDARD) OF THE MOST COMMON CANCERS IN FEMALESBULGARIA 1981-2006
2006
2006
15
AGE-ADJUSTED (WORLD STANDARD) INCIDENCE RATES PER 100 000 FOR ALL CANCERS BY DISTRICTSIN BULGARIA 2006 - MALES
< 228.69from 228.70 to 242.59
from 242.60 to 250.09
from 250.10 to 275.89> 275.90
AGE-ADJUSTED (WORLD STANDARD) INCIDENCE RATES PER 100 000 FOR ALL CANCERS BY DISTRICTSIN BULGARIA 2006 - FEMALES
< 182.29from 182.30 to 195.59
from 195.60 to 202.29
from 202.30 to 218.39> 218.40
16
NUMB
ER O
F NE
W C
ANCE
R CA
SES
BY P
RIMA
RY S
ITES
AND
AGE
AT
DIAG
NOSI
S IN
BUL
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A 20
06 –
MALE
S
CODE
ICD-
10SI
TEA
GE
AT D
IAG
NO
SIS
0-4
5-9
10-1
415
-19
20-2
425
-29
30-3
435
-39
40-4
445
-49
50-5
455
-59
60-6
465
-69
70-7
475
-79
80-8
485
+A
LLA
GES
C00-
97AL
L SI
TES
3724
2434
6395
140
214
364
742
1331
2134
2372
2565
2758
2218
1210
429
1675
4C0
0LI
P-
--
--
-1
1-
211
2016
2627
2112
414
1C0
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--
--
--
--
-2
11
-1
11
-7
C00.1
--
--
--
11
-2
815
1023
2519
103
117
C00.3
--
--
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1-
-1
--
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2C0
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43
11
11
112
C00.8
--
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--
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21
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--
--
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--
34
414
97
115
31
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--
--
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34
1211
1217
42
1-
71C0
2.0-
--
--
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1-
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C02.1
--
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22
23
58
11
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29C0
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--
--
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--
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13
11
1-
-9
C02.3
--
--
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13
--
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11
--
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C02.9
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43
34
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33
65
32
1-
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--
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23
31
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--
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--
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21
32
2-
1-
-11
C03.9
--
--
--
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--
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--
1C0
4FL
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OF M
OUTH
--
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32
1815
73
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41
11
--
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C04.1
--
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81
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43
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76
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41
11
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Part
1
17Part
2NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
ULGA
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2006
– MA
LES
CODE
ICD-
10SI
TEA
GE
AT D
IAG
NO
SIS
0-4
5-9
10-1
415
-19
20-2
425
-29
30-3
435
-39
40-4
445
-49
50-5
455
-59
60-6
465
-69
70-7
475
-79
80-8
485
+A
LLA
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C09
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--
--
--
-5
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2512
54
21
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32
21
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--
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24
--
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510
179
33
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18 Part
3NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
ULGA
RIA
2006
– MA
LES
CODE
ICD-
10SI
TEA
GE
AT D
IAG
NO
SIS
0-4
5-9
10-1
415
-19
20-2
425
-29
30-3
435
-39
40-4
445
-49
50-5
455
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60-6
465
-69
70-7
475
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80-8
485
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818
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114
148
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19Part
4NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
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RIA
2006
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CODE
ICD-
10SI
TEA
GE
AT D
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NO
SIS
0-4
5-9
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415
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20
20 Part
5NU
MBER
OF
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CAN
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CASE
S BY
PRI
MARY
SIT
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ND A
GE A
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AGNO
SIS
IN B
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2006
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CODE
ICD-
10SI
TEA
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0-4
5-9
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415
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465
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2
21Part
6NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
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2006
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CODE
ICD-
10SI
TEA
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NO
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5-9
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415
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435
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455
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465
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475
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485
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916
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164
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11
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2242
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22 Part
7NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
ULGA
RIA
2006
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LES
CODE
ICD-
10SI
TEA
GE
AT D
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NO
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0-4
5-9
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415
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23Part
8NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
ULGA
RIA
2006
– MA
LES
CODE
ICD-
10SI
TEA
GE
AT D
IAG
NO
SIS
0-4
5-9
10-1
415
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20-2
425
-29
30-3
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24 Part
9NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
ULGA
RIA
2006
– MA
LES
CODE
ICD-
10SI
TEA
GE
AT D
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0-4
5-9
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25Part
10NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
ULGA
RIA
2006
– MA
LES
CODE
ICD-
10SI
TEA
GE
AT D
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NO
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0-4
5-9
10-1
415
-19
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425
-29
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-39
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-49
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-59
60-6
465
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475
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485
+A
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MULT
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26
NUMB
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F NE
W C
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SES
BY P
RIMA
RY S
ITES
AND
AGE
AT
DIAG
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S IN
BUL
GARI
A 20
06 –
FEMA
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CODE
ICD-
10SI
TEA
GE
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NO
SIS
0-4
5-9
10-1
415
-19
20-2
425
-29
30-3
435
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40-4
445
-49
50-5
455
-59
60-6
465
-69
70-7
475
-79
80-8
485
+A
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C00-
97AL
L SI
TES
3217
1632
6410
324
444
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BASE
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R OF
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55
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SPEC
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1
Part
1
27Part
2NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
ULGA
RIA
2006
– FE
MALE
S
CODE
ICD-
10SI
TEA
GE
AT D
IAG
NO
SIS
0-4
5-9
10-1
415
-19
20-2
425
-29
30-3
435
-39
40-4
445
-49
50-5
455
-59
60-6
465
-69
70-7
475
-79
80-8
485
+A
LLA
GES
C09.9
--
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1-
5C1
0OR
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RYNX
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13
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FINE
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TES
IN L
IP, O
RAL
CAVI
TY
AND
PHAR
YNX
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SOPH
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22
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21
214
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218
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STOM
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32
120
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11
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14
28 Part
3NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
ULGA
RIA
2006
– FE
MALE
S
CODE
ICD-
10SI
TEA
GE
AT D
IAG
NO
SIS
0-4
5-9
10-1
415
-19
20-2
425
-29
30-3
435
-39
40-4
445
-49
50-5
455
-59
60-6
465
-69
70-7
475
-79
80-8
485
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LLA
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C17.2
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1
29Part
4NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
ULGA
RIA
2006
– FE
MALE
S
CODE
ICD-
10SI
TEA
GE
AT D
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NO
SIS
0-4
5-9
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415
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425
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435
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465
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UN
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S1
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33
11
-18
30 Part
5NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
ULGA
RIA
2006
– FE
MALE
S
CODE
ICD-
10SI
TEA
GE
AT D
IAG
NO
SIS
0-4
5-9
10-1
415
-19
20-2
425
-29
30-3
435
-39
40-4
445
-49
50-5
455
-59
60-6
465
-69
70-7
475
-79
80-8
485
+A
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C41.0
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C48
RETR
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ITON
EUM
AND
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TONE
UM-
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34
54
38
63
447
31Part
6NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
ULGA
RIA
2006
– FE
MALE
S
CODE
ICD-
10SI
TEA
GE
AT D
IAG
NO
SIS
0-4
5-9
10-1
415
-19
20-2
425
-29
30-3
435
-39
40-4
445
-49
50-5
455
-59
60-6
465
-69
70-7
475
-79
80-8
485
+A
LLA
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C48.0
--
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12
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11
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32
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13
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23
53
21
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32 Part
7NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
ULGA
RIA
2006
– FE
MALE
S
CODE
ICD-
10SI
TEA
GE
AT D
IAG
NO
SIS
0-4
5-9
10-1
415
-19
20-2
425
-29
30-3
435
-39
40-4
445
-49
50-5
455
-59
60-6
465
-69
70-7
475
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80-8
485
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C56
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77
66
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44
33Part
8NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
ULGA
RIA
2006
– FE
MALE
S
CODE
ICD-
10SI
TEA
GE
AT D
IAG
NO
SIS
0-4
5-9
10-1
415
-19
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425
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435
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1-
4
34 Part
9NU
MBER
OF
NEW
CAN
CER
CASE
S BY
PRI
MARY
SIT
ES A
ND A
GE A
T DI
AGNO
SIS
IN B
ULGA
RIA
2006
– FE
MALE
S
CODE
ICD-
10SI
TEA
GE
AT D
IAG
NO
SIS
0-4
5-9
10-1
415
-19
20-2
425
-29
30-3
435
-39
40-4
445
-49
50-5
455
-59
60-6
465
-69
70-7
475
-79
80-8
485
+A
LLA
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C82.7
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1-
41
22
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C83
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NON-
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61
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48
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5
35Part
10NU
MBER
OF
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41Part
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48 Part
3CA
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INCI
DENC
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100 0
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AND
AGE
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CODE
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49Part
4CA
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INCI
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PER
100 0
00 B
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AND
AGE
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C09
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147
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C11
148
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C12
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149
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151
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C11
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HYPO
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C12
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00.
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00.
0-
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C14
150
OESO
PHAG
US0.
20.
40.
30.
30.
20.
30.
30.
20.
30.
30.
40.
50.
40.
40.
60.
40.
50.
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1515
1ST
OMAC
H13
.210
.39.
08.
48.
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97.
57.
97.
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88.
38.
47.
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37.
27.
67.
07.
3C
1615
2SM
ALL I
NTES
TINE
0.1
0.1
0.0
0.1
0.2
0.1
0.1
0.1
0.1
0.2
0.2
0.1
0.2
0.3
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0.2
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C17
153
COLO
N7.
37.
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98.
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48.
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39.
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010
.510
.011
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1815
4RE
CTUM
6.6
6.6
6.3
7.2
7.5
7.0
8.1
7.6
8.4
7.6
8.2
8.8
8.2
8.4
7.9
8.4
8.7
9.0
9.3
C19
-21
155
LIVER
2.8
1.7
2.0
2.0
1.6
1.8
2.1
2.3
2.1
2.2
2.8
3.1
2.8
2.0
2.1
2.2
2.1
2.4
2.4
C22
156
GALL
BLAD
DER
ETC.
2.3
2.2
1.7
1.8
1.5
1.5
1.5
1.2
1.6
1.5
1.9
1.9
2.0
1.6
1.8
2.0
1.6
1.9
1.8
C23
-24
157
PANC
REAS
2.9
2.8
3.0
3.4
3.0
3.5
3.2
3.3
3.3
3.4
4.4
4.0
4.8
4.2
4.0
4.9
5.1
4.8
5.0
C25
158
PERI
TONE
UM E
TC.
0.6
0.4
0.5
0.4
0.5
0.4
0.4
0.6
0.6
0.7
0.7
0.7
0.6
0.7
0.6
0.7
0.7
0.5
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C48
, C
45.1
159
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TES
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E OR
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C26
160
NOSE
, SIN
USES
ETC
.0.
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10.
20.
20.
10.
30.
20.
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20.
20.
20.
20.
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30-3
116
1LA
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0.3
0.3
0.2
0.3
0.2
0.5
0.2
0.3
0.3
0.2
0.3
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0.5
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C32
162
BRON
CHUS
, LUN
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416
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0.2
0.2
0.1
0.2
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0.2
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C38
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TORA
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0.1
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0.2
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0.3
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0.3
0.3
0.3
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0.3
0.3
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C37
, C
38.0
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C39
170
BONE
0.6
0.4
0.5
0.5
0.6
0.8
0.6
0.7
0.7
0.5
0.9
0.8
1.0
0.7
0.8
0.8
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0.8
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C40
-41
AGE-
ADJU
STED
(WOR
LD S
TAND
ARD)
INCI
DENC
E RA
TES
PER
100 0
00 B
Y PR
IMAR
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SITE
S AND
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R OF
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GNOS
IS IN
BUL
GARI
A 19
81 - 2
006,
FEMA
LES
CODE
IC
D-9
SITE
YEAR
OF
DIAG
NOSI
SC
OD
E
ICD
-10
1981
1985
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
59
171
CONN
ECTI
VE T
ISSU
E3.
01.
01.
11.
21.
81.
21.
31.
61.
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21.
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C49
172
MELA
NOMA
OF
SKIN
1.7
1.5
1.5
2.0
2.4
2.2
2.1
1.9
2.3
2.4
2.5
2.7
1.8
2.3
2.2
2.1
2.8
2.1
2.2
C43
173
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R SK
IN20
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4417
4BR
EAST
32.1
35.8
37.6
38.6
43.3
40.8
45.0
45.1
45.9
46.5
46.1
46.5
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49.8
49.6
51.8
51.9
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51.8
C50
179
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US U
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5518
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RI10
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5818
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411
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8.7
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11.1
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12.3
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C56
, C
57.0
-418
4OT
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FEMA
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ENITA
L
1.0
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1.5
1.3
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1.2
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1.3
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1.8
1.6
1.6
1.5
1.6
1.5
1.9
1.7
1.7
C51
, C
52,
C57
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188
BLAD
DER
1.5
1.7
1.5
1.5
1.8
1.8
1.6
1.9
2.1
1.9
2.0
2.3
2.3
2.6
2.4
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3.0
3.3
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C67
189
KIDN
EY E
TC.
1.3
1.5
1.8
1.6
1.6
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2.1
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2.2
2.5
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C64
-66,
C
6819
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10.
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40.
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40.
30.
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6919
1BR
AIN
2.6
2.4
2.4
2.5
2.7
2.5
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2.5
2.2
4.4
4.0
3.6
3.6
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C71
192
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R PA
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OF
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C72
193
THYR
OID
3.0
2.4
1.6
1.9
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1.9
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2.5
2.7
2.5
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C73
194
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519
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20.
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20.
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20.
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7619
9NE
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SM W
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IFIC
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SIT
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8020
0+20
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HOMA
1.5
1.6
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1.7
1.8
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2.8
2.9
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2.9
2.8
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C82
-85,
C
9620
1HO
DGKI
N’S
DISE
ASE
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1.0
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2.0
1.8
2.0
1.4
1.3
1.6
1.7
1.3
1.5
1.4
C81
203
MULT
IPLE
MYE
LOMA
0.6
0.4
0.5
0.6
0.5
0.5
0.7
0.7
0.4
0.7
0.9
1.0
0.8
0.9
1.1
1.0
1.4
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C88
, C
9020
4LY
MPHO
ID LE
UKAE
MIA
1.4
0.9
0.9
1.1
1.5
1.2
1.0
1.4
1.6
1.7
2.2
2.5
2.0
1.7
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2.4
1.9
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2.7
C91
205
MYEL
OID
LEUK
AEMI
A1.
00.
50.
40.
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80.
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--
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0.2
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0.1
0.0
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C93
207
OTHE
R LE
UKAE
MIA
0.1
0.0
0.0
0.1
0.1
0.0
0.1
0.1
0.1
0.0
0.1
0.3
0.1
0.3
0.3
0.3
0.5
0.1
0.1
C94
208
LEUK
AEMI
A, C
ELL
UNSP
ECIF
IED
0.9
0.9
0.9
0.8
0.8
0.6
0.8
0.8
0.5
0.8
0.9
0.8
0.6
0.4
0.4
0.4
0.5
0.7
0.5
C95
Part
2AG
E-AD
JUST
ED (W
ORLD
STA
NDAR
D) IN
CIDE
NCE
RATE
S PE
R 10
0 000
BY
PRIM
ARY
CANC
ER S
ITES A
ND Y
EAR
OF D
IAGN
OSIS
IN B
ULGA
RIA
1981
- 200
6, FE
MALE
SCO
DE
ICD-
9SI
TEYE
AR O
F DI
AGNO
SIS
CO
DE
IC
D-1
019
8119
8519
9019
9119
9219
9319
9419
9519
9619
9719
9819
9920
0020
0120
0220
0320
0420
0520
06
60
C00-97 ALL SITES M 90.59 95.88 96.60 88.06 83.45 80.54 78.41 68.89 78.17F 93.85 94.79 96.25 95.06 94.33 91.14 86.10 71.15 85.89
C00 LIP M - - 100.00 100.00 100.00 100.00 100.00 100.00 100.00F - - - - 100.00 100.00 94.44 93.10 95.16
C01 BASE OF TONGUE M - - 100.00 100.00 100.00 65.22 61.11 11.11 62.90F - - 100.00 - 100.00 50.00 - 20.00 33.33
C02 OTHER AND UNSPECIFIED PARTS OF TONGUE
M - - 100.00 85.71 93.75 86.96 85.71 100.00 88.73F - - 100.00 100.00 100.00 85.71 100.00 100.00 95.45
C03 GUM M - - - - 100.00 100.00 100.00 100.00 100.00F - - - 100.00 100.00 100.00 75.00 75.00 85.71
C04 FLOOR OF MOUTH M - - - 100.00 100.00 95.45 100.00 100.00 98.11F - - - 100.00 100.00 - 100.00 - 66.67
C05 PALATE M - - - 100.00 83.33 100.00 100.00 100.00 94.12F - - - - - 100.00 100.00 - 100.00
C06 OTHER AND UNSPECIFIED PARTS OF MOUTH
M - - 100.00 100.00 100.00 80.00 75.00 100.00 86.67F - - - 100.00 - 100.00 100.00 100.00 100.00
C07 PAROTID GLAND M - - 100.00 100.00 85.71 100.00 100.00 100.00 97.92F - 100.00 100.00 100.00 100.00 75.00 100.00 77.78 91.43
C08 OTHER AND UNSPECIFIED MAJOR SALIVARY GLANDS
M - - - - 100.00 66.67 90.00 66.67 77.78F - - - 100.00 - 100.00 100.00 100.00 100.00
C09 TONSIL M - - - 100.00 95.00 86.49 88.89 100.00 90.54F - - - - - 100.00 100.00 100.00 100.00
C10 OROPHARYNX M - - 100.00 - 100.00 88.24 100.00 83.33 93.33F - - - - 100.00 100.00 100.00 25.00 62.50
C11 NASOPHARYNX M 100.00 100.00 - 100.00 100.00 93.75 100.00 100.00 97.83F - 100.00 100.00 100.00 - 100.00 87.50 50.00 90.91
C12 PYRIFORM SINUS M - - - - - 66.67 - - 40.00C13 HYPOPHARYNX M - - 100.00 66.67 95.65 100.00 83.33 - 91.67
F - - - - 100.00 - 100.00 100.00 75.00C14 OTHER AND ILL-DEFINED SITES IN
LIP, ORAL CAVITY AND PHARYNXM - - - - 100.00 50.00 100.00 - 71.43F - - 100.00 - - 100.00 - - 33.33
C15 OESOPHAGUS M - - 100.00 60.00 65.52 77.27 72.73 29.17 66.86F - - - - 100.00 50.00 83.33 18.18 48.84
C16 STOMACH M - 100.00 100.00 84.85 88.54 80.99 73.47 53.90 71.35F - 100.00 75.00 86.36 84.09 84.48 78.57 47.53 65.91
C17 SMALL INTESTINE M - - 100.00 - 100.00 71.43 25.00 50.00 59.26F - 100.00 100.00 - 100.00 100.00 100.00 50.00 85.00
C18 COLON M - 100.00 100.00 97.14 93.86 88.39 85.71 74.08 84.11F - 100.00 80.00 92.86 95.24 91.64 89.70 72.42 84.98
C19 RECTOSIGMOID JUNCTION M - - - - 81.25 78.13 73.44 53.13 67.23F - - 100.00 100.00 92.31 92.59 71.43 45.45 66.46
C20 RECTUM M - - 100.00 75.00 97.17 94.09 93.95 81.08 91.47F - 100.00 100.00 100.00 96.83 96.53 94.26 80.93 91.21
C21 ANUS AND ANAL CANAL M - - 100.00 - 100.00 87.50 100.00 83.33 92.59F - - - - 100.00 100.00 100.00 40.00 75.00
C22 LIVER AND INTRAHEPATIC BILE DUCTS
M - 66.67 75.00 50.00 50.88 48.00 46.94 34.29 45.14F - - 100.00 33.33 61.54 60.00 37.78 30.12 39.91
C23 GALLBLADDER M - - - 100.00 100.00 80.00 46.67 33.33 52.94F - - - 100.00 44.44 85.00 85.45 48.84 70.31
C24 OTHER AND UNSPECIFIED PARTS OF BILIARY TRACT
M - - - - 88.89 81.25 69.23 52.94 68.42F - - - 100.00 100.00 75.00 61.54 83.33 75.68
C25 PANCREAS M - - 100.00 69.23 50.00 56.98 47.72 32.65 48.01F - 50.00 100.00 80.00 63.16 56.10 53.85 29.22 47.42
C26 OTHER AND ILL-DEFINED DIGESTIVE ORGANS M - - - - 33.33 - - - 7.14
C30 NASAL CAVITY AND MIDDLE EAR M - 100.00 - 100.00 100.00 100.00 50.00 100.00 83.33F - - - - - 100.00 - 66.67 75.00
C31 ACCESSORY SINUSES M - - 100.00 - 66.67 85.71 100.00 50.00 83.33F - - - - 100.00 75.00 100.00 100.00 91.67
Part 1PERCENTAGE DISTRIBUTION OF MORPHOLOGICALLY VERIFIED CANCER CASES BY PRIMARY SITES, SEX AND AGE AT DIAGNOSIS IN BULGARIA 2006
CODEICD-10 SITE SEX
AGE AT DIAGNOSIS
0-14 15-24 25-34 35-44 45-54 55-64 65-74 75+ ALL AGES
61
C32 LARYNX M - - - 100.00 94.70 90.08 82.68 73.17 88.62F - - - 100.00 100.00 100.00 75.00 80.00 94.44
C33 TRACHEA M - - - 100.00 100.00 100.00 100.00 - 100.00F - - - - 100.00 - - - 50.00
C34 BRONCHUS AND LUNG M - 100.00 83.33 74.24 76.33 70.58 64.88 41.71 65.99F - 100.00 - 75.76 77.38 74.27 66.88 36.77 63.25
C37 THYMUS M - - 100.00 100.00 100.00 100.00 100.00 - 100.00F - - 100.00 - 100.00 100.00 - - 80.00
C38 HEART, MEDIASTINUM, AND PLEURA
M 100.00 100.00 100.00 - 100.00 66.67 50.00 - 50.00F - - - - 100.00 50.00 - - 30.00
C40 BONES, JOINTS AND ARTICULAR CARTILAGE OF LIMBS
M 100.00 100.00 100.00 100.00 100.00 40.00 100.00 - 80.95F 100.00 100.00 100.00 - 80.00 66.67 50.00 - 73.91
C41 BONES, JOINTS AND ARTICULAR CARTILAGE OF OTHER AND UNSPECIFIED SITES
M - 100.00 100.00 50.00 100.00 100.00 25.00 - 58.82
F 100.00 100.00 - 100.00 50.00 100.00 50.00 50.00 72.22C43 MELANOMA OF SKIN M 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00
F - 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00C44 OTHER SKIN M - 100.00 100.00 98.08 100.00 99.70 99.83 99.17 99.54
F - 100.00 100.00 100.00 100.00 100.00 100.00 99.51 99.80C45 MESOTHELIOMA M - - - 100.00 100.00 100.00 100.00 100.00 100.00
F - - 100.00 100.00 100.00 100.00 100.00 - 100.00C46 KAPOSI’S SARCOMA M - - - - - 100.00 100.00 100.00 100.00
F - - - - - - - 100.00 100.00C47 PERIPHERAL NERVES AND
AUTONOMIC NERVOUS SYSTEMM 100.00 - - - 100.00 100.00 - - 75.00F 100.00 - - - - 100.00 - - 100.00
C48 RETROPERITONEUM AND PERITONEUM
M 100.00 100.00 - 100.00 75.00 84.62 50.00 50.00 74.19F - - 75.00 - 71.43 77.78 72.73 38.46 59.57
C49 CONNECTIVE AND OTHER SOFT TISSUES
M 100.00 100.00 100.00 100.00 100.00 96.00 95.45 92.86 96.67F 100.00 100.00 100.00 100.00 100.00 94.44 93.33 76.92 94.57
C50 BREAST M - - - 100.00 100.00 100.00 91.67 90.00 94.34F - 100.00 98.41 98.60 97.39 95.97 94.78 82.93 94.06
C51 VULVAF - - 100.00 100.00 90.91 90.91 94.23 97.44 95.00
C52 VAGINAF - - 100.00 100.00 100.00 80.00 100.00 100.00 96.67
C53 CERVIX UTERIF - 100.00 98.96 99.23 99.39 98.94 93.79 90.32 97.85
C54 CORPUS UTERIF - - 100.00 100.00 99.15 99.06 97.10 90.06 97.32
C55 UTERUS, NOSF - - 100.00 66.67 77.78 100.00 55.56 38.89 59.09
C56 OVARYF 100.00 94.12 100.00 96.00 95.51 94.55 82.63 59.69 86.62
C57 OTHER AND UNSPECIFIED FEMALE GENITAL ORGANS F - - - 50.00 100.00 100.00 66.67 66.67 76.00
C58 PLACENTAF - - 100.00 100.00 - - - - 100.00
C60 PENISM - - 100.00 100.00 87.50 94.12 81.82 91.67 90.20
C61 PROSTATE GLANDM - - - 100.00 85.71 89.92 90.59 77.81 84.78
C62 TESTISM 100.00 100.00 98.57 100.00 100.00 92.31 81.82 50.00 96.91
C63 OTHER AND UNSPECIFIED MALE GENITAL ORGANS M - - - - 100.00 100.00 66.67 100.00 83.33
C64 KIDNEY M 100.00 - 100.00 88.46 81.82 84.55 69.09 50.68 74.32F 100.00 100.00 83.33 84.21 92.68 87.93 85.96 63.89 84.16
C65 RENAL PELVIS M - - - 100.00 100.00 91.67 100.00 100.00 97.50F - - - - 100.00 100.00 100.00 100.00 100.00
Part 2PERCENTAGE DISTRIBUTION OF MORPHOLOGICALLY VERIFIED CANCER CASES BY PRIMARY SITES, SEX AND AGE AT DIAGNOSIS IN BULGARIA 2006
CODEICD-10 SITE SEX
AGE AT DIAGNOSIS
0-14 15-24 25-34 35-44 45-54 55-64 65-74 75+ ALL AGES
62
Part 3
C66 URETER M - - - - - 100.00 66.67 50.00 62.50F - - - - 100.00 50.00 100.00 100.00 87.50
C67 BLADDER M - - 100.00 88.89 95.35 96.26 91.33 80.99 90.45F - 100.00 100.00 100.00 95.45 97.06 92.86 81.44 91.17
C68 OTHER AND UNSPECIFIED URNARY ORGANS
M - - - - - 100.00 - 50.00 50.00F - - - - - 100.00 - 100.00 100.00
C69 EYE AND ADNEXA M 100.00 - 100.00 100.00 100.00 100.00 100.00 100.00 100.00F 50.00 - 100.00 - 100.00 100.00 87.50 80.00 87.50
C70 MENINGES M - - - 100.00 100.00 66.67 75.00 33.33 75.00F - - - - 100.00 100.00 50.00 66.67 84.00
C71 BRAIN M 66.67 92.86 95.24 89.29 76.00 64.71 54.93 36.36 66.57F 75.00 75.00 81.25 79.17 83.72 70.51 59.70 23.53 63.23
C72 SPINAL CORD, CRANIAL NERVES, AND OTHER PARTS OF CENTRALNERVOUS SYSTEM
M 100.00 - 100.00 - 33.33 - 33.33 - 36.36
F 100.00 100.00 100.00 100.00 - 50.00 - - 60.00C73 THYROID GLAND M - 100.00 100.00 100.00 100.00 80.00 100.00 66.67 91.30
F 100.00 100.00 100.00 97.14 98.04 98.00 92.86 68.00 94.01C74 ADRENAL GLAND M - 100.00 - 100.00 71.43 66.67 50.00 - 66.67
F 100.00 100.00 - 100.00 100.00 66.67 20.00 - 53.33C75 OTHER ENDOCRINE GLANDS AND
RELATED STRUCTURESM 100.00 - - - - - 100.00 - 66.67F - - 100.00 100.00 100.00 - - - 100.00
C76 OTHER AND ILL-DEFINED SITES M - - - 100.00 - 75.00 60.00 - 64.29F - - - - 66.67 33.33 42.86 20.00 38.89
C80 MALIGNANT NEOPLASM WITHOUT SPECIFICATION OF SITE
M - 50.00 33.33 60.00 42.59 39.65 32.11 20.86 34.03
F - - 71.43 52.94 52.73 39.66 31.01 24.83 35.11C81 HODGKIN’S DISEASE M 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00
F 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00C82 FOLLICULAR NON-HODGKIN’S
LYMPHOMAM - - 100.00 100.00 100.00 100.00 100.00 100.00 100.00F - - 100.00 100.00 100.00 100.00 100.00 100.00 100.00
C83 DIFFUSE NON-HODGKIN’S LYMPHOMA
M 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00F - 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00
C84 PERIPHERAL AND CUTANEOUS T-CELL LYMPHOMAS
M 100.00 - 100.00 - 100.00 100.00 100.00 100.00 100.00F 100.00 - - 100.00 100.00 100.00 100.00 100.00 100.00
C85 OTHER AND UNSPECIFIED TYPES OF NON-HODGKIN’S LYMPHOMA
M 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00F 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00
C88 MALIGNANT IMMUNOPROLIFERATIVE DISEASES
M - 100.00 - - - 100.00 100.00 100.00 100.00
F - - - - - - 100.00 - 100.00C90 MULTIPLE MYELOMA AND
MALIGNANT PLASMA CELL NEOPLASMS
M - - - 100.00 100.00 100.00 100.00 100.00 100.00
F - - - - 100.00 100.00 100.00 100.00 100.00C91 LYMPHOID LEUKAEMIA M 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00
F 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00C92 MYELOID LEUKAEMIA M 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00
F 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00C93 MONOCYTIC LEUKAEMIA M - - - - - 100.00 100.00 - 100.00
F - 100.00 - 100.00 100.00 100.00 100.00 100.00 100.00C94 OTHER LEUKAEMIAS OF
SPECIFIED CELL TYPEM - - - 100.00 100.00 100.00 100.00 100.00 100.00F - - - - 100.00 100.00 100.00 100.00 100.00
C95 LEUKAEMIA, UNSPECIFIED CELL TYPE
M - - 100.00 100.00 100.00 100.00 100.00 100.00 100.00F 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00 100.00
C96 OTHER AND UNSPECIFIED NEOPLASMS OF LYMPHOID, BLOOD FORMING AND RELATED TISSUES
M 100.00 - 100.00 100.00 100.00 - - - 100.00
F - - - - - 100.00 - 100.00 100.00
PERCENTAGE DISTRIBUTION OF MORPHOLOGICALLY VERIFIED CANCER CASES BY PRIMARY SITES, SEX AND AGE AT DIAGNOSIS IN BULGARIA 2006
CODEICD-10 SITE SEX
AGE AT DIAGNOSIS
0-14 15-24 25-34 35-44 45-54 55-64 65-74 75+ ALL AGES
63
ALL
3637
100.
0-
5310
0.0
-35
8410
0.0
-W
ITHO
UT M
ORPH
OLOG
Y21
65.
9-
35.
7-
213
5.9
-W
ITH
MORP
HOLO
GY34
2194
.110
0.0
5094
.310
0.0
3371
94.1
100.
080
013
TUMO
R CE
LLS,
MAL
IGNA
NT13
63.
74.
0-
--
136
3.8
4.0
8010
3CA
RCIN
OMA,
NOS
110.
30.
31
1.9
2.0
100.
30.
380
203
CARC
INOM
A, U
NDIF
FERE
NTIA
TED,
NOS
170.
50.
5-
--
170.
50.
580
213
CARC
INOM
A ANA
PLAS
TIC,
NOS
30.
10.
1-
--
30.
10.
180
503
PAPI
LLAR
Y CA
RCIN
OMA,
NOS
80.
20.
2-
--
80.
20.
281
403
ADEN
OCAR
CINO
MA, N
OS34
0.9
1.0
35.
76.
031
0.9
0.9
8141
3SC
IRRH
OUS
ADEN
OCAR
CINO
MA16
0.4
0.5
--
-16
0.4
0.5
8200
3AD
ENOI
D CY
STIC
CAR
CINO
MA1
0.0
0.0
--
-1
0.0
0.0
8201
3CR
IBRI
FORM
CAR
CINO
MA7
0.2
0.2
--
-7
0.2
0.2
8211
3TU
BULA
R AD
ENOC
ARCI
NOMA
150.
40.
42
3.8
4.0
130.
40.
482
603
PAPI
LLAR
Y AD
ENOC
ARCI
NOMA
, NOS
20.
10.
1-
--
20.
10.
184
403
CYST
ADEN
OCAR
CINO
MA, N
OS1
0.0
0.0
11.
92.
0-
--
8480
3MU
CINO
US A
DENO
CARC
INOM
A69
1.9
2.0
--
-69
1.9
2.0
8481
3MU
CIN
- PRO
DUCI
NG A
DENO
CARC
INOM
A9
0.2
0.3
--
-9
0.3
0.3
8490
3SI
GNET
RIN
G CE
LL C
ARCI
NOMA
10.
00.
0-
--
10.
00.
085
003
INFI
LTRA
TING
DUC
T CA
RCIN
OMA
2238
61.5
65.4
3362
.366
.022
0561
.565
.485
013
COME
DOCA
RCIN
OMA,
NOS
250.
70.
7-
--
250.
70.
785
033
INTR
ADUC
TAL P
APILL
ARY
ADEN
OCAR
CINO
MA, W
ITH
INVA
SION
150.
40.
4-
--
150.
40.
485
043
INTR
ACYS
TIC
CARC
INOM
A, N
OS3
0.1
0.1
--
-3
0.1
0.1
8510
3ME
DULL
ARY
CARC
INOM
A, N
OS61
1.7
1.8
11.
92.
060
1.7
1.8
8512
3ME
DULL
ARY
CARC
INOM
A W
ITH
LYMP
HOID
STR
OMA
20.
10.
1-
--
20.
10.
185
203
LOBU
LAR
CARC
INOM
A, N
OS59
816
.417
.57
13.2
14.0
591
16.5
17.5
8522
3IN
FILT
RATI
NG D
UCT A
ND LO
BULA
R CA
RCIN
OMA
117
3.2
3.4
11.
92.
011
63.
23.
485
303
INFL
AMMA
TORY
CAR
CINO
MA3
0.1
0.1
--
-3
0.1
0.1
8540
3PA
GET
DISE
ASE,
MAM
MARY
120.
30.
4-
--
120.
30.
485
413
PAGE
T DI
SEAS
E AN
D IN
FILT
RATI
NG D
UCT
CARC
INOM
A OF
BRE
AST
10.
00.
0-
--
10.
00.
085
433
PAGE
T DI
SEAS
E AN
D IN
TRAD
UCTA
L CAR
CINO
MA O
F BR
EAST
30.
10.
1-
--
30.
10.
185
503
ACIN
AR C
ELL C
ARCI
NOMA
10.
00.
0-
--
10.
00.
085
603
ADEN
OSQU
AMOU
S CA
RCIN
OMA
10.
00.
0-
--
10.
00.
088
503
LIPOS
ARCO
MA, N
OS1
0.0
0.0
11.
92.
0-
--
8852
3MY
XOID
LIPO
SARC
OMA
10.
00.
0-
--
10.
00.
088
543
PLEO
MORP
HIC
LIPOS
ARCO
MA1
0.0
0.0
--
-1
0.0
0.0
8980
3CA
RCIN
OSAR
COMA
, NOS
40.
10.
1-
--
40.
10.
189
903
MESE
NCHY
MOMA
, MAL
IGNA
NT1
0.0
0.0
--
-1
0.0
0.0
9020
3PH
YLLO
DES
TUMO
R, M
ALIG
NANT
30.
10.
1-
--
30.
10.
1
NUMB
ER A
ND P
ERCE
NTAG
E OF
NEW
BRE
AST
CANC
ER C
ASES
BY
HIST
OLOG
IC T
YPE
AND
SEX
IN B
ULGA
RIA
2006
CODE
IC
D-10
MORP
HOLO
GY
ALL
MALE
SFE
MALE
S
NUMB
ER%
FRO
M AL
L
% F
ROM
MORP
HO-
LOGI
CALL
Y CO
NFIR
MED
NUMB
ER%
FRO
M AL
L
% F
ROM
MORP
HO-
LOGI
CALL
Y CO
NFIR
MED
NUMB
ER%
FRO
M AL
L
% F
ROM
MORP
HO-
LOGI
CALL
Y CO
NFIR
MED
64
ALL
3683
100.
0-
3077
100.
0-
606
100.
0-
WIT
HOUT
MOR
PHOL
OGY
1267
34.4
-10
4433
.9-
223
36.8
-W
ITH
MORP
HOLO
GY24
1665
.610
0.0
2033
66.1
100.
038
363
.210
0.0
8001
3TU
MOR
CELL
S, M
ALIG
NANT
661.
82.
752
1.7
2.6
142.
33.
780
103
CARC
INOM
A, N
OS16
0.4
0.7
140.
50.
72
0.3
0.5
8012
3LA
RGE
CELL
CAR
CINO
MA, N
OS70
1.9
2.9
591.
92.
911
1.8
2.9
8020
3CA
RCIN
OMA,
UND
IFFE
RENT
IATE
D, N
OS39
1.1
1.6
361.
21.
83
0.5
0.8
8021
3CA
RCIN
OMA,
ANA
PLAS
TIC,
NOS
30.
10.
11
0.0
0.0
20.
30.
580
223
PLEO
MORP
HIC
CARC
INOM
A1
0.0
0.0
10.
00.
0-
--
8031
3GI
ANT
CELL
CAR
CINO
MA17
0.5
0.7
170.
60.
8-
--
8032
3SP
INDL
E CE
LL C
ARCI
NOMA
10.
00.
0-
--
10.
20.
380
413
SMAL
L CEL
L CAR
CINO
MA, N
OS30
38.
212
.525
28.
212
.451
8.4
13.3
8042
3OA
T CE
LL C
ARCI
NOMA
170.
50.
716
0.5
0.8
10.
20.
380
433
SMAL
L CEL
L CAR
CINO
MA, F
USIF
ORM
CELL
10.
00.
01
0.0
0.0
--
-80
453
COMB
INED
SMA
LL C
ELL C
ARCI
NOMA
20.
10.
12
0.1
0.1
--
-80
503
PAPI
LLAR
Y CA
RCIN
OMA,
NOS
20.
10.
11
0.0
0.0
10.
20.
380
523
PAPI
LLAR
Y SQ
UAMO
US C
ELL C
ARCI
NOMA
20.
10.
12
0.1
0.1
--
-80
703
SQUA
MOUS
CEL
L CAR
CINO
MA, N
OS13
4436
.555
.611
9638
.958
.814
824
.438
.680
713
SQUA
MOUS
CEL
L CAR
CINO
MA, K
ERAT
INIZ
ING,
NOS
661.
82.
759
1.9
2.9
71.
21.
880
723
SQUA
MOUS
CEL
L CAR
CINO
MA, L
ARGE
CEL
L, NO
NKER
ATIN
IZIN
G31
0.8
1.3
290.
91.
42
0.3
0.5
8073
3SQ
UAMO
US C
ELL C
ARCI
NOMA
, SMA
LL C
ELL,
NONK
ERAT
INIZ
ING
10.
00.
01
0.0
0.0
--
-80
743
SQUA
MOUS
CEL
L CAR
CINO
MA, S
PIND
LE C
ELL
20.
10.
12
0.1
0.1
--
-81
403
ADEN
OCAR
CINO
MA, N
OS24
66.
710
.215
45.
07.
692
15.2
24.0
8200
3AD
ENOI
D CY
STIC
CAR
CINO
MA3
0.1
0.1
10.
00.
02
0.3
0.5
8240
3CA
RCIN
OID
TUMO
R, N
OS14
0.4
0.6
80.
30.
46
1.0
1.6
8244
3CO
MPOS
ITE
CARC
INOI
D1
0.0
0.0
--
-1
0.2
0.3
8245
3AD
ENOC
ARCI
NOID
TUM
OR1
0.0
0.0
10.
00.
0-
--
8246
3NE
UROE
NDOC
RINE
CAR
CINO
MA, N
OS3
0.1
0.1
20.
10.
11
0.2
0.3
8250
3BR
ONCH
IOLO
- ALV
EOLA
R AD
ENOC
ARCI
NOMA
491.
32.
032
1.0
1.6
172.
84.
482
513
ALVE
OLAR
ADE
NOCA
RCIN
OMA
20.
10.
12
0.1
0.1
--
-82
603
PAPI
LLAR
Y AD
ENOC
ARCI
NOMA
, NOS
220.
60.
916
0.5
0.8
61.
01.
683
103
CLEA
R CE
LL A
DENO
CARC
INOM
A, N
OS8
0.2
0.3
50.
20.
23
0.5
0.8
8430
3MU
COEP
IDER
MOID
CAR
CINO
MA14
0.4
0.6
120.
40.
62
0.3
0.5
8480
3MU
CINO
US A
DENO
CARC
INOM
A2
0.1
0.1
20.
10.
1-
--
8481
3MU
CIN
- PRO
DUCI
NG A
DENO
CARC
INOM
A13
0.4
0.5
110.
40.
52
0.3
0.5
8490
3SI
GNET
RIN
G CE
LL C
ARCI
NOMA
10.
00.
01
0.0
0.0
--
-85
503
ACIN
AR C
ELL C
ARCI
NOMA
20.
10.
12
0.1
0.1
--
-85
603
ADEN
OSQU
AMOU
S CA
RCIN
OMA
481.
32.
042
1.4
2.1
61.
01.
688
103
FIBR
OSAR
COMA
, NOS
10.
00.
0-
--
10.
20.
389
003
RHAB
DOMY
OSAR
COMA
, NOS
10.
00.
01
0.0
0.0
--
-91
503
HEMA
NGIO
PERI
CYTO
MA, M
ALIG
NANT
10.
00.
0-
--
10.
20.
3
NUMB
ER A
ND P
ERCE
NTAG
E OF
NEW
LUN
G (IN
CL. T
RACH
EA A
ND B
RONC
HUS)
CAN
CER
CASE
S BY
HIS
TOLO
GIC
TYPE
AND
SEX
IN B
ULGA
RIA
2006
CODE
IC
D-10
MORP
HOLO
GY
ALL
MALE
SFE
MALE
S
NUMB
ER%
FRO
M AL
L
% F
ROM
MORP
HO-
LOGI
CALL
Y CO
NFIR
MED
NUMB
ER%
FRO
M AL
L
% F
ROM
MORP
HO-
LOGI
CALL
Y CO
NFIR
MED
NUMB
ER%
FRO
M AL
L
% F
ROM
MORP
HO-
LOGI
CALL
Y CO
NFIR
MED
65
ALL
2487
100.
0-
1315
100.
0-
1172
100.
0-
WIT
HOUT
MOR
PHOL
OGY
385
15.5
-20
915
.9-
176
15.0
-
WIT
H MO
RPHO
LOGY
2102
84.5
100.
011
0684
.110
0.0
996
85.0
100.
0
8001
3TU
MOR
CELL
S, M
ALIG
NANT
20.
10.
11
0.1
0.1
10.
10.
1
8010
3CA
RCIN
OMA,
NOS
100.
40.
55
0.4
0.5
50.
40.
5
8020
3CA
RCIN
OMA,
UND
IFFE
RENT
IATE
D, N
OS10
0.4
0.5
40.
30.
46
0.5
0.6
8021
3CA
RCIN
OMA,
ANA
PLAS
TIC,
NOS
30.
10.
11
0.1
0.1
20.
20.
2
8050
3PA
PILL
ARY
CARC
INOM
A, N
OS1
0.0
0.0
10.
10.
1-
--
8070
3SQ
UAMO
US C
ELL C
ARCI
NOMA
, NOS
10.
00.
01
0.1
0.1
--
-
8140
3AD
ENOC
ARCI
NOMA
, NOS
1613
64.9
76.7
863
65.6
78.0
750
64.0
75.3
8144
3AD
ENOC
ARCI
NOMA
, INTE
STIN
AL T
YPE
271.
11.
315
1.1
1.4
121.
01.
2
8210
3AD
ENOC
ARCI
NOMA
IN A
DENO
MATO
US P
OLYP
50.
20.
23
0.2
0.3
20.
20.
2
8211
3TU
BULA
R AD
ENOC
ARCI
NOMA
30.
10.
13
0.2
0.3
--
-
8240
3CA
RCIN
OID
TUMO
R, N
OS5
0.2
0.2
40.
30.
41
0.1
0.1
8243
3GO
BLET
CEL
L CAR
CINO
ID2
0.1
0.1
--
-2
0.2
0.2
8260
3PA
PILL
ARY
ADEN
OCAR
CINO
MA, N
OS83
3.3
3.9
453.
44.
138
3.2
3.8
8261
3AD
ENOC
ARCI
NOMA
IN V
ILLOU
S AD
ENOM
A8
0.3
0.4
40.
30.
44
0.3
0.4
8262
3VI
LLOU
S AD
ENOC
ARCI
NOMA
90.
40.
45
0.4
0.5
40.
30.
4
8263
3AD
ENOC
ARCI
NOMA
IN T
UBUL
OVILL
OUS
ADEN
OMA
241.
01.
114
1.1
1.3
100.
91.
0
8480
3MU
CINO
US A
DENO
CARC
INOM
A96
3.9
4.6
524.
04.
744
3.8
4.4
8481
3MU
CIN-
PROD
UCIN
G AD
ENOC
ARCI
NOMA
194
7.8
9.2
816.
27.
311
39.
611
.3
8490
3SI
GNET
RIN
G CE
LL C
ARCI
NOMA
20.
10.
11
0.1
0.1
10.
10.
1
8560
3AD
ENOS
QUAM
OUS
CARC
INOM
A1
0.0
0.0
10.
10.
1-
--
8854
3PL
EOMO
RPHI
C LIP
OSAR
COMA
10.
00.
01
0.1
0.1
--
-
8940
3MI
XED
TUMO
R, M
ALIG
NANT
, NOS
10.
00.
01
0.1
0.1
--
-
9150
3HE
MANG
IOPE
RICY
TOMA
, MAL
IGNA
NT1
0.0
0.0
--
-1
0.1
0.1
NUMB
ER A
ND P
ERCE
NTAG
E OF
NEW
COL
ON C
ANCE
R CA
SES
BY H
ISTO
LOGI
C TY
PE A
ND S
EX IN
BUL
GARI
A 20
06
CO
DE
ICD
-10
MO
RPH
OLO
GY
ALL
MA
LES
FEM
ALE
S
NU
MB
ER%
FR
OM
ALL
% F
RO
M
MO
RPH
O-
LOG
ICA
LLY
CO
NFI
RM
EDN
UM
BER
% F
RO
M A
LL%
FR
OM
M
OR
PHO
-LO
GIC
ALL
Y C
ON
FIR
MED
NU
MB
ER%
FR
OM
ALL
% F
RO
M
MO
RPH
O-
LOG
ICA
LLY
CO
NFI
RM
ED
66
ALL
1931
100.
0-
1118
100.
0-
813
100.
0-
WIT
HOUT
MOR
PHOL
OGY
252
13.1
-13
812
.3-
114
14.0
-
WIT
H G
Y16
7986
.910
0.0
980
87.7
100.
069
986
.010
0.0
8001
3TU
MOR
CELL
S, M
ALIG
NANT
10.
10.
1-
--
10.
10.
1
8010
3CA
RCIN
OMA,
NOS
80.
40.
54
0.4
0.4
40.
50.
6
8020
3CA
RCIN
OMA,
UND
IFFE
RENT
IATE
D, N
OS4
0.2
0.2
30.
30.
31
0.1
0.1
8050
3PA
PILL
ARY
CARC
INOM
A, N
OS2
0.1
0.1
--
-2
0.2
0.3
8051
3VE
RRUC
OUS
CARC
INOM
A, N
OS1
0.1
0.1
10.
10.
1-
--
8070
3SQ
UAMO
US C
ELL C
ARCI
NOMA
, NOS
180.
91.
19
0.8
0.9
91.
11.
3
8071
3SQ
UAMO
US C
ELL C
ARCI
NOMA
, KER
ATIN
IZIN
G, N
OS6
0.3
0.4
40.
40.
42
0.2
0.3
8072
3SQ
UAMO
US C
ELL C
ARCI
NOMA
, LAR
GE C
ELL,
NONK
ERAT
INIZ
ING,
NOS
10.
10.
11
0.1
0.1
--
-
8076
3SQ
UAMO
US C
ELL C
ARCI
NOMA
, MIC
ROIN
VASI
VE1
0.1
0.1
--
-1
0.1
0.1
8123
3BA
SALO
ID C
ARCI
NOMA
20.
10.
12
0.2
0.2
--
-
8140
3AD
ENOC
ARCI
NOMA
, NOS
1293
67.0
77.0
765
68.4
78.1
528
64.9
75.5
8141
3SC
IRRH
OUS
ADEN
OCAR
CINO
MA1
0.1
0.1
10.
10.
1-
--
8144
3AD
ENOC
ARCI
NOMA
, INTE
STIN
AL T
YPE
150.
80.
98
0.7
0.8
70.
91.
0
8210
3AD
ENOC
ARCI
NOMA
IN A
DENO
MATO
US P
OLYP
100.
50.
66
0.5
0.6
40.
50.
6
8221
3AD
ENOC
ARCI
NOMA
IN M
ULTI
PLE
ADEN
OMAT
OUS
POLY
PS1
0.1
0.1
--
-1
0.1
0.1
8240
3CA
RCIN
OID
TUMO
R, N
OS1
0.1
0.1
--
-1
0.1
0.1
8260
3PA
PILL
ARY
ADEN
OCAR
CINO
MA, N
OS70
3.6
4.2
413.
74.
229
3.6
4.1
8261
3AD
ENOC
ARCI
NOMA
IN V
ILLOU
S AD
ENOM
A16
0.8
1.0
70.
60.
79
1.1
1.3
8262
3VI
LLOU
S AD
ENOC
ARCI
NOMA
160.
81.
08
0.7
0.8
81.
01.
1
8263
3AD
ENOC
ARCI
NOMA
IN T
UBUL
OVILL
OUS
ADEN
OMA
201.
01.
29
0.8
0.9
111.
41.
6
8480
3MU
CINO
US A
DENO
CARC
INOM
A52
2.7
3.1
292.
63.
023
2.8
3.3
8481
3MU
CIN-
PROD
UCIN
G AD
ENOC
ARCI
NOMA
125
6.5
7.4
746.
67.
651
6.3
7.3
8490
3SI
GNET
RIN
G CE
LL C
ARCI
NOMA
50.
30.
31
0.1
0.1
40.
50.
6
8560
3AD
ENOS
QUAM
OUS
CARC
INOM
A4
0.2
0.2
40.
40.
4-
--
8720
3MA
LIGNA
NT M
ELAN
OMA,
NOS
20.
10.
11
0.1
0.1
10.
10.
1
8890
3LE
IOMY
OSAR
COMA
, NOS
20.
10.
11
0.1
0.1
10.
10.
1
8891
3EP
ITHE
LIOID
LEIO
MYOS
ARCO
MA1
0.1
0.1
--
-1
0.1
0.1
8980
3CA
RCIN
OSAR
COMA
, NOS
10.
10.
11
0.1
0.1
--
-
NUMB
ER A
ND P
ERCE
NTAG
E OF
NEW
REC
TUM
AND
ANUS
CAN
CER
CASE
S BY
HIS
TOLO
GIC
TYPE
AND
SEX
IN B
ULGA
RIA
2006
CO
DE
ICD
-10
MO
RPH
OLO
GY
ALL
MA
LES
FEM
ALE
S
NU
MB
ER%
FR
OM
ALL
% F
RO
M
MO
RPH
O-
LOG
ICA
LLY
CO
NFI
RM
ED
NU
MB
ER%
FR
OM
ALL
% F
RO
M
MO
RPH
O-
LOG
ICA
LLY
CO
NFI
RM
ED
NU
MB
ER%
FR
OM
ALL
% F
RO
M
MO
RPH
O-
LOG
ICA
LLY
CO
NFI
RM
ED
67
CODE ICD-10 MORPHOLOGY
ALL
NUMBER % FROM ALL % FROM MORPHO-LOGICALLY CONFIRMED
ALL 1208 100.0 -WITHOUT MORPHOLOGY 26 2.2 -WITH MORPHOLOGY 1182 97.8 100.0
80103 CARCINOMA, NOS 4 0.3 0.380203 CARCINOMA, UNDIFFERENTIATED, NOS 4 0.3 0.380213 CARCINOMA, ANAPLASTIC, NOS 1 0.1 0.180503 PAPILLARY CARCINOMA, NOS 3 0.2 0.380513 VERRUCOUS CARCINOMA, NOS 2 0.2 0.280523 PAPILLARY SQUAMOUS CELL CARCINOMA 6 0.5 0.580703 SQUAMOUS CELL CARCINOMA, NOS 771 63.8 65.280713 SQUAMOUS CELL CARCINOMA, KERATINIZING, NOS 77 6.4 6.580723 SQUAMOUS CELL CARCINOMA, LARGE CELL, NONKERATINIZING 89 7.4 7.580733 SQUAMOUS CELL CARCINOMA, SMALL CELL, NONKERATINIZING 6 0.5 0.580743 SQUAMOUS CELL CARCINOMA, SPINDLE CELL 1 0.1 0.180763 SQUAMOUS CELL CARCINOMA, MICROINVASIVE 65 5.4 5.581403 ADENOCARCINOMA, NOS 55 4.6 4.782603 PAPILLARY ADENOCARCINOMA, NOS 26 2.2 2.282623 VILLOUS ADENOCARCINOMA 2 0.2 0.283103 CLEAR CELL ADENOCARCINOMA, NOS 7 0.6 0.683803 ENDOMETRIOID CARCINOMA 3 0.2 0.384303 MUCOEPIDERMOID CARCINOMA 1 0.1 0.184803 MUCINOUS ADENOCARCINOMA 2 0.2 0.284813 MUCIN - PRODUCING ADENOCARCINOMA 1 0.1 0.185603 ADENOSQUAMOUS CARCINOMA 50 4.1 4.285703 ADENOCARCINOMA WITH SQUAMOUS METAPLASIA 2 0.2 0.288503 LIPOSARCOMA, NOS 1 0.1 0.188903 LEIOMYOSARCOMA, NOS 2 0.2 0.291103 MESONEPHROMA, MALIGNANT 1 0.1 0.1
NUMBER AND PERCENTAGE OF NEW CERVIX UTERI CANCER CASES BY HISTOLOGIC TYPE IN BULGARIA 2006
CODE ICD-10 MORPHOLOGY
ALL
NUMBER % FROM ALL % FROM MORPHO-LOGICALLY CONFIRMED
ALL 1459 100.0 -WITHOUT MORPHOLOGY 222 15.2 -WITH MORPHOLOGY 1237 84.8 100.0
80013 TUMOR CELLS, MALIGNANT 15 1.0 1.280103 CARCINOMA, NOS 18 1.2 1.580203 CARCINOMA, UNDIFFERENTIATED, NOS 10 0.7 0.880213 CARCINOMA ANAPLASTIC, NOS 4 0.3 0.380703 SQUAMOUS CELL CARCINOMA, NOS 1 0.1 0.181203 TRANSITIONAL CELL CARCINOMA 3 0.2 0.281403 ADENOCARCINOMA, NOS 1140 78.1 92.281903 TRABECULAR ADENOCARCINOMA 4 0.3 0.382013 CRIBRIFORM CARCINOMA 4 0.3 0.382303 SOLID CARCINOMA, NOS 1 0.1 0.183103 CLEAR CELL ADENOCARCINOMA, NOS 6 0.4 0.584803 MUCINOUS ADENOCARCINOMA 1 0.1 0.185503 ACINAR CELL CARCINOMA 30 2.1 2.4
NUMBER AND PERCENTAGE OF NEW PROSTATE CANCER CASES BY HISTOLOGIC TYPE IN BULGARIA 2006
68
C00-97 ALL SITES 275.8 279.6 248.1 267.5 283.9 239.6 261.4 274.1 243.5 225.8 198.5 245.9C00 LIP 1.0 3.0 2.4 0.6 1.9 4.5 0.0 1.0 2.4 1.6 0.0 3.2C01 BASE OF TONGUE 0.7 2.6 3.8 3.0 0.8 0.0 0.0 2.8 0.0 0.4 0.0 0.0C02 OTHER AND UNSPECIFIED
PARTS OF TONGUE 1.2 0.2 0.0 0.7 1.8 2.9 1.4 1.1 0.0 0.3 1.0 0.9C03 GUM 0.2 0.3 0.0 0.0 0.3 0.5 0.0 0.5 1.4 0.0 0.0 0.7C04 FLOOR OF MOUTH 0.8 0.3 1.8 1.5 0.6 0.7 0.9 1.2 1.1 1.6 0.0 4.1C05 PALATE 0.2 0.6 0.0 0.0 0.6 0.7 0.0 1.1 0.0 0.0 0.0 0.5C06 OTHER AND UNSPECIFIED
PARTS OF MOUTH 0.1 0.0 0.8 0.4 0.3 1.4 0.0 0.5 0.0 0.0 0.8 0.0C07 PAROTID GLAND 1.3 0.3 0.0 0.5 0.3 0.3 2.4 0.7 0.9 0.7 0.3 1.1C08 OTHER AND UNSPECIFIED
MAJOR SALIVARY GLANDS 0.5 0.2 1.2 0.7 0.3 0.0 0.0 0.2 0.8 0.0 0.0 0.0C09 TONSIL 1.4 1.1 2.0 0.8 0.6 2.0 1.6 0.4 1.7 0.0 0.8 1.5C10 OROPHARYNX 0.5 0.3 2.0 0.0 1.0 0.3 2.2 0.0 0.0 0.0 1.8 0.0C11 NASOPHARYNX 0.9 1.2 1.7 1.4 0.3 2.9 1.6 0.0 0.0 0.8 0.0 1.6C12 PYRIFORM SINUS 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0C13 HYPOPHARYNX 1.4 3.4 0.0 0.8 0.0 0.0 3.3 2.0 0.0 0.3 0.0 2.7C14 OTHER AND ILL-DEFINED
SITES IN LIP, ORAL CAVITY AND PHARYNX 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0
C15 OESOPHAGUS 3.5 3.1 0.7 3.2 2.9 2.9 2.4 3.3 3.0 1.3 2.5 2.8C16 STOMACH 12.7 9.5 14.9 19.5 16.2 16.6 11.5 12.8 25.9 11.6 13.2 12.5C17 SMALL INTESTINE 0.3 0.6 0.9 0.6 1.8 0.0 0.5 0.0 0.3 0.0 0.0 0.0C18 COLON 23.8 13.4 17.6 19.4 23.5 22.6 11.6 17.0 18.6 19.4 12.5 14.9C19 RECTOSIGMOID JUNCTION 4.8 3.9 1.0 0.9 1.6 0.3 4.0 2.0 0.3 1.9 2.2 4.0C20 RECTUM 13.3 12.8 15.3 17.2 12.7 17.0 13.9 19.2 17.4 11.7 13.8 13.8C21 ANUS AND ANAL CANAL 0.4 0.3 0.0 0.7 0.4 0.0 0.8 0.2 0.0 0.0 0.0 1.4C22 LIVER AND INTRAHEPATIC
BILE DUCTS 6.3 14.2 7.1 8.0 7.6 8.6 2.5 7.1 4.6 0.9 2.7 7.2C23 GALLBLADDER 0.6 0.4 1.7 0.5 0.9 0.7 0.7 0.9 0.4 0.2 0.5 1.2C24 OTHER AND UNSPECIFIED
PARTS OF BILIARY TRACT 0.6 1.7 0.5 0.8 1.2 1.8 3.2 0.8 0.4 0.8 0.0 1.8C25 PANCREAS 10.9 8.1 12.7 10.1 10.1 12.9 6.9 9.2 5.8 12.1 10.2 12.6C26 OTHER AND ILL-DEFINED
DIGESTIVE ORGANS 0.4 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3C30 NASAL CAVITY AND MIDDLE
EAR 0.4 0.2 0.5 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0C31 ACCESSORY SINUSES 0.4 1.0 0.0 0.7 0.9 0.0 2.7 0.0 0.0 0.0 1.8 0.8C32 LARYNX 9.7 9.6 6.9 15.8 8.5 11.3 9.6 10.0 8.1 11.6 8.1 6.4C33 TRACHEA 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0C34 BRONCHUS AND LUNG 44.5 45.8 48.0 49.0 50.1 45.8 60.3 66.8 45.8 47.7 33.7 44.4C37 THYMUS 0.3 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0C38 HEART, MEDIASTINUM, AND
PLEURA 0.3 0.6 0.0 0.8 0.7 0.0 1.1 0.7 0.0 0.0 0.0 0.0C39 OTHER AND ILL-DEFINED
SITES WITHIN RESPIRATORY SYSTEM AND INTRATHORACIC ORGANS 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
C40 BONES, JOINTS AND ARTICULAR CARTILAGE OF LIMBS 0.4 0.2 0.0 1.5 0.6 0.5 1.9 1.4 0.0 0.5 0.0 0.6
C41 BONES, JOINTS AND ARTICULAR CARTILAGE OF OTHER AND UNSPECIFIED SITES 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.5
C43 MELANOMA OF SKIN 5.1 4.0 1.9 1.9 4.3 1.7 1.0 0.9 5.5 1.3 4.0 0.4
AGE-ADJUSTED (WORLD STANDARD) INCIDENCE RATES OF CANCER PER 100 000CODEICD-10 SITE
DISTRICT
Sofi a city Bourgas Yambol Sliven Varna Dobrich Shoumen Veliko Tarnovo Gabrovo Pleven Lovech Vratsa
69
202.9 235.5 280.6 246.6 228.6 304.4 249.6 265.0 242.5 241.7 227.2 243.7 239.3 283.7 290.8 266.5
1.3 1.9 1.8 1.1 0.9 3.4 4.6 4.0 3.1 2.3 1.4 0.0 3.2 3.8 3.2 2.8
0.0 0.7 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 7.9 0.0 1.0 0.0
1.0 0.8 1.9 1.2 0.0 0.4 1.0 4.0 1.0 0.6 3.6 0.0 1.3 1.9 3.0 0.0
1.0 0.0 0.0 0.0 0.9 1.4 0.0 0.0 2.3 1.5 0.0 0.0 0.7 1.0 0.0 0.0
0.3 0.0 1.0 0.5 1.2 0.4 1.6 1.2 2.0 0.0 1.4 1.0 0.7 0.7 1.0 0.0
1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.8 0.5 0.0
1.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.0
0.0 0.0 0.9 0.2 0.0 2.2 1.8 0.0 0.0 0.0 1.8 1.0 0.6 0.0 1.0 1.0
0.0 0.0 0.2 0.5 0.0 1.3 0.0 0.8 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0
3.9 2.1 1.2 1.0 0.0 1.6 0.9 3.8 5.0 1.1 2.6 2.0 0.4 0.6 1.1 1.0
0.0 0.8 0.6 0.5 0.0 0.7 0.8 2.8 0.9 0.6 0.0 4.7 0.4 2.2 0.0 1.8
1.0 2.3 0.4 1.3 0.0 1.2 3.7 0.0 0.0 0.4 0.0 1.0 0.5 0.7 1.1 1.0
0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0
2.9 0.2 0.8 0.5 0.0 1.6 2.1 1.1 0.0 1.7 0.9 1.6 0.9 0.0 0.9 0.0
0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0
5.8 3.9 2.2 1.7 3.2 2.6 1.6 2.3 2.4 3.3 5.2 2.0 1.9 2.5 2.2 0.0
5.5 15.7 19.1 13.4 28.0 12.2 19.3 20.9 14.7 18.1 10.0 10.2 20.2 14.2 18.3 28.3
0.0 0.0 0.2 0.0 1.5 0.4 0.0 0.9 0.0 0.0 0.9 0.8 0.9 0.8 0.0 0.5
12.9 16.5 23.0 19.3 6.9 26.4 14.1 20.2 19.2 17.2 12.5 13.4 16.9 21.8 22.4 17.5
0.7 2.2 1.9 0.5 1.7 3.0 2.9 4.2 0.0 1.0 1.2 4.1 0.6 3.9 2.7 0.5
18.4 17.6 13.1 12.1 9.6 17.2 6.7 16.6 19.5 8.4 9.6 11.0 14.7 16.0 14.8 10.2
0.0 0.0 0.4 1.2 0.0 2.2 1.3 0.0 1.3 0.6 0.0 0.8 0.4 0.2 0.0 0.0
7.3 4.1 11.1 9.0 4.8 3.8 4.6 6.9 4.6 3.5 3.8 0.0 7.6 7.4 5.1 6.8
0.0 0.8 0.8 0.0 1.0 2.2 0.0 1.7 0.7 0.8 0.3 1.1 0.0 0.6 0.5 0.6
0.0 0.6 0.9 0.0 0.0 1.2 0.0 0.8 2.1 0.6 0.9 0.0 0.2 1.0 1.0 0.0
6.7 5.3 9.8 10.7 7.5 12.7 4.5 7.7 2.4 11.0 8.1 10.3 4.6 8.8 10.9 7.8
0.4 0.9 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0
2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 1.0 0.9 0.0 0.0 0.0 0.0 0.0
0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.9 0.3 0.0 1.0 0.0 0.0 0.5 0.0
8.8 6.1 10.3 6.4 7.5 10.6 15.5 10.2 5.3 8.0 14.4 13.8 8.0 13.2 9.9 8.9
0.9 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0
39.0 45.2 52.3 52.5 48.7 54.6 60.5 48.3 61.4 39.7 38.0 43.8 37.2 54.8 67.8 67.2
0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0
0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.3 2.4 0.0
0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
0.0 0.0 0.6 0.0 0.0 0.0 1.0 0.0 1.1 2.2 0.0 0.0 0.0 0.0 1.0 0.0
0.0 0.0 0.2 0.9 1.0 1.4 0.8 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0
2.8 2.9 3.3 3.8 4.0 3.3 0.8 0.0 3.3 3.1 1.8 3.9 1.3 4.5 2.5 1.3
BY PRIMARY SITES AND DISTRICTS IN BULGARIA 2006 - MALESDISTRICT
Vidin Montana Plovdiv Pazardjik Smolyan Rousse Razgrad Silistra Targovi-shte
Sofi a district
Kyus-tendil Pernik Blagoev-
gradStara
Zagora Haskovo Kurdjali
Part 1
70
C44 OTHER SKIN 22.4 40.2 14.8 24.3 30.6 14.3 27.0 23.5 13.5 22.6 13.7 22.4C45 MESOTHELIOMA 0.1 0.8 0.0 0.0 0.0 0.5 0.0 0.6 0.8 0.6 0.0 1.2C46 KAPOSI’S SARCOMA 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0C47 PERIPHERAL NERVES AND
AUTONOMIC NERVOUS SYSTEM 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.8 0.0 0.0 0.0
C48 RETROPERITONEUM AND PERITONEUM 0.8 0.5 1.0 0.7 0.3 0.0 1.5 2.7 0.0 0.4 0.0 0.4
C49 CONNECTIVE AND OTHER SOFT TISSUES 2.5 1.4 0.8 0.0 1.0 0.0 0.0 1.1 0.6 1.3 1.4 0.9
C50 BREAST 0.8 0.2 3.1 0.0 1.0 2.0 0.0 1.4 0.8 0.4 0.9 2.7C60 PENIS 1.3 0.4 0.5 0.4 0.0 0.5 0.8 0.0 0.0 2.0 0.3 1.5C61 PROSTATE GLAND 27.8 17.5 15.0 13.3 22.8 8.1 16.9 17.3 17.1 13.4 16.9 22.9C62 TESTIS 5.4 7.9 2.5 2.2 6.2 4.8 5.1 2.7 0.0 1.7 1.1 1.6C63 OTHER AND UNSPECIFIED
MALE GENITAL ORGANS 0.1 0.0 0.4 0.7 0.2 0.0 0.0 0.3 0.6 0.0 0.0 0.0C64 KIDNEY 6.1 10.4 11.3 10.2 9.7 8.8 7.0 6.3 8.7 5.1 7.0 3.8C65 RENAL PELVIS 0.9 0.7 0.0 1.2 0.3 0.0 0.4 0.9 0.9 0.2 1.4 1.8C66 URETER 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0C67 BLADDER 22.7 16.3 24.7 12.2 16.6 14.7 18.7 16.0 16.3 15.7 16.3 12.8C68 OTHER AND UNSPECIFIED
URINARY ORGANS 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0C69 EYE AND ADNEXA 0.0 0.5 2.0 0.0 0.7 0.7 0.0 0.4 0.0 1.5 0.0 0.5C70 MENINGES 0.4 1.2 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0C71 BRAIN 7.8 5.4 7.4 6.5 8.0 7.8 7.1 5.7 13.9 1.7 4.4 3.3C72 SPINAL CORD, CRANIAL
NERVES, AND OTHER PARTS OF CENTRAL NERVOUS SYSTEM 0.3 0.0 3.2 0.0 0.6 1.2 0.0 0.6 0.0 0.0 0.0 0.0
C73 THYROID GLAND 1.3 1.4 0.9 0.7 1.1 0.0 0.0 1.4 0.0 0.6 1.8 0.0C74 ADRENAL GLAND 0.4 0.3 0.0 0.0 0.6 0.8 0.0 0.0 1.1 0.6 0.0 0.0C75 OTHER ENDOCRINE GLANDS
AND RELATED STRUCTURES 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8C76 OTHER AND ILL-DEFINED
SITES 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0C80 MALIGNANT NEOPLASM
WITHOUT SPECIFICATION OF SITE 8.2 13.3 4.7 12.8 11.8 5.2 15.0 11.1 6.4 20.0 14.9 11.2
C81 HODGKIN’S DISEASE 2.0 2.4 1.2 2.5 2.7 1.1 1.1 1.4 1.4 2.0 0.0 2.0C82 FOLLICULAR NON-HODGKIN’S
LYMPHOMA 0.1 0.7 0.0 0.0 1.8 0.0 0.9 0.0 0.0 0.4 0.0 0.0C83 DIFFUSE NON-HODGKIN’S
LYMPHOMA 2.8 2.0 0.0 0.7 3.9 0.0 1.2 2.9 5.8 1.2 0.0 3.1C84 PERIPHERAL AND CUTANEOUS
T-CELL LYMPHOMAS 0.6 0.0 0.0 0.0 0.5 1.1 0.0 0.6 0.0 0.6 0.0 0.5C85 OTHER AND UNSPECIFIED
TYPES OF NON-HODGKIN’S LYMPHOMA 2.2 1.8 1.3 2.2 1.1 2.3 1.1 2.1 0.6 1.6 2.0 0.6
C88 MALIGNANT IMMUNOPROLIFERATIVE DISEASES 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0
C90 MULTIPLE MYELOMA AND MALIGNANT PLASMA CELL NEOPLASMS 1.6 1.4 0.0 1.2 1.1 2.6 0.9 2.1 1.9 1.4 1.9 0.5
C91 LYMPHOID LEUKAEMIA 4.5 4.8 3.0 7.0 4.5 1.9 2.4 4.3 3.3 0.9 0.9 6.3C92 MYELOID LEUKAEMIA 1.9 2.1 2.3 5.1 2.2 1.1 2.6 2.4 1.3 1.1 0.0 1.3C93 MONOCYTIC LEUKAEMIA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0C94 OTHER LEUKAEMIAS OF
SPECIFIED CELL TYPE 0.1 0.2 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0C95 LEUKAEMIA, UNSPECIFIED
CELL TYPE 0.6 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.6 2.9 0.4C96 OTHER AND UNSPECIFIED
NEOPLASMS OF LYMPHOID,BLOOD FORMING ANDRELATED TISSUES 0.1 0.0 0.0 1.9 0.0 0.0 0.8 0.0 0.0 1.1 0.0 0.0
AGE-ADJUSTED (WORLD STANDARD) INCIDENCE RATES OF CANCER PER 100 000CODEICD-10 SITE
DISTRICT
Sofi a city Bourgas Yambol Sliven Varna Dobrich Shoumen Veliko Tarnovo Gabrovo Pleven Lovech Vratsa
71
Part 2
20.9 20.6 24.3 26.5 18.2 34.9 33.6 25.2 18.8 19.5 18.0 18.4 31.4 27.4 23.3 24.1
0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.0
0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0
0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0
0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 1.6 1.9
1.2 1.5 2.0 2.3 3.4 1.8 1.0 4.7 0.0 1.1 4.2 5.2 0.7 1.8 2.2 2.7
0.0 0.5 0.6 0.5 1.0 1.0 3.3 0.0 1.1 0.6 1.0 0.0 0.5 0.7 0.5 1.4
0.4 0.8 0.1 0.0 0.0 1.2 0.0 0.0 1.1 2.6 3.2 3.2 1.6 0.6 0.5 0.0
7.7 15.4 24.5 17.2 17.7 13.3 10.9 13.8 13.4 17.9 20.2 21.7 18.0 18.8 15.4 16.2
3.3 5.2 4.3 6.5 1.8 3.4 1.7 0.0 1.8 5.3 4.1 0.8 5.8 9.3 5.6 1.0
0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
8.6 8.8 5.2 5.0 6.0 7.6 2.6 3.2 2.9 4.9 3.3 8.8 5.8 7.5 4.7 10.6
0.0 1.2 0.4 1.1 0.0 0.6 0.0 0.0 1.3 0.0 0.7 0.0 0.0 0.7 0.6 0.6
0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.7 0.0 0.0 0.0
9.1 19.4 17.4 14.6 19.8 21.3 11.1 14.9 16.7 11.9 14.7 16.9 10.4 14.6 18.1 17.1
0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0
0.0 0.0 1.1 0.0 0.0 0.0 1.4 0.0 0.0 2.2 0.0 0.0 0.0 0.5 0.3 0.0
0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 1.3 0.4 0.0 0.0 0.0 0.4 0.0 0.0
3.5 6.9 8.6 10.9 5.4 2.8 2.9 7.9 8.2 9.8 3.1 11.0 4.4 6.0 10.4 8.5
1.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0
0.0 0.9 0.6 0.0 2.2 1.4 0.9 0.8 1.1 1.0 0.9 0.0 1.1 1.3 0.0 0.0
0.0 0.0 0.6 1.5 0.0 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0
0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
1.7 0.0 0.0 1.7 0.0 1.7 0.0 0.9 0.0 0.3 3.5 0.0 0.0 0.8 0.0 0.0
8.3 10.3 9.7 6.7 9.5 22.3 10.9 14.0 12.6 11.5 11.4 14.5 14.7 10.7 17.1 11.3
1.5 1.2 2.6 2.7 1.1 5.3 4.5 0.9 0.0 5.8 0.0 0.0 0.5 1.4 2.5 1.9
1.0 0.9 0.4 0.2 0.0 0.0 2.2 1.2 0.0 0.2 2.0 0.3 0.5 0.7 0.5 1.0
0.6 0.0 2.6 1.1 2.0 1.4 7.1 1.6 0.9 2.4 1.6 4.0 2.5 2.7 1.6 4.6
0.0 0.9 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.9 0.0 0.6 1.4 0.2 0.0
4.3 0.4 1.6 2.4 0.0 3.0 0.0 0.5 0.7 2.5 3.2 1.6 0.0 1.1 2.1 1.0
0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
0.4 0.4 1.9 0.7 4.2 0.8 0.0 1.5 0.5 0.4 0.5 1.3 0.8 1.4 1.0 0.0
2.9 3.9 5.7 3.0 2.0 3.4 0.0 5.8 1.0 11.4 3.0 1.9 2.1 4.1 3.4 1.0
0.4 3.3 2.3 1.3 4.7 1.9 2.4 1.4 1.3 0.2 4.4 1.9 1.7 6.3 2.0 3.5
0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
0.0 0.0 0.3 0.0 0.0 1.3 0.0 1.8 1.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0
0.0 1.0 0.4 0.0 0.0 0.7 0.0 0.0 1.2 0.4 0.7 0.8 0.0 0.0 0.0 0.6
0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
BY PRIMARY SITES AND DISTRICTS IN BULGARIA 2006 - MALESDISTRICT
Vidin Montana Plovdiv Pazardjik Smolyan Rousse Razgrad Silistra Targovi-shte
Sofi a district
Kyus-tendil Pernik Blagoev-
gradStara
Zagora Haskovo Kurdjali
72
C00-97 ALL SITES 245.2 231.6 195.5 201.2 218.3 201.9 202.2 209.6 199.9 190.2 189.2 239.0C00 LIP 0.3 1.2 0.2 0.6 0.4 0.4 0.4 1.0 0.0 0.3 0.0 1.5C01 BASE OF TONGUE 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0C02 OTHER AND UNSPECIFIED
PARTS OF TONGUE 0.5 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.8 0.0 0.0 0.5C03 GUM 0.1 0.5 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0C04 FLOOR OF MOUTH 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0C05 PALATE 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0C06 OTHER AND UNSPECIFIED
PARTS OF MOUTH 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0C07 PAROTID GLAND 0.3 0.0 0.7 0.7 0.4 0.0 0.6 0.4 1.0 1.3 0.0 0.5C08 OTHER AND UNSPECIFIED
MAJOR SALIVARY GLANDS 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0C09 TONSIL 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0C10 OROPHARYNX 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2C11 NASOPHARYNX 0.4 0.5 0.7 0.0 0.2 1.3 0.0 0.4 0.0 0.9 0.7 0.0C13 HYPOPHARYNX 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0C14 OTHER AND ILL-DEFINED
SITES IN LIP, ORAL CAVITY AND PHARYNX 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
C15 OESOPHAGUS 0.5 0.4 0.9 0.8 0.6 0.0 1.2 1.4 0.3 0.0 0.0 0.5C16 STOMACH 4.9 8.2 10.9 5.9 5.5 7.3 6.3 9.1 9.8 4.5 7.2 7.8C17 SMALL INTESTINE 0.4 0.6 0.0 0.0 0.3 0.0 0.0 0.2 1.5 0.0 0.0 0.0C18 COLON 17.3 9.0 21.9 12.5 13.8 8.4 10.1 13.0 12.3 12.2 9.4 10.4C19 RECTOSIGMOID JUNCTION 3.1 2.1 2.2 0.7 0.6 0.8 3.9 1.4 1.0 3.8 2.5 1.9C20 RECTUM 7.8 8.2 5.5 6.1 10.4 4.7 6.7 12.9 6.6 7.8 5.2 6.3C21 ANUS AND ANAL CANAL 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.6C22 LIVER AND INTRAHEPATIC
BILE DUCTS 2.4 6.1 1.8 2.0 4.6 3.7 1.9 1.1 0.0 0.3 1.3 3.5C23 GALLBLADDER 1.9 2.1 3.3 0.8 1.1 3.0 1.7 0.2 0.7 1.4 1.5 1.6C24 OTHER AND UNSPECIFIED
PARTS OF BILIARY TRACT 0.2 1.0 1.3 0.2 0.3 0.4 1.1 0.0 0.2 0.2 1.9 0.7C25 PANCREAS 7.3 4.2 3.2 3.6 5.5 4.3 6.1 2.9 5.2 4.5 2.6 3.4C26 OTHER AND ILL-DEFINED
DIGESTIVE ORGANS 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1C30 NASAL CAVITY AND MIDDLE
EAR 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0C31 ACCESSORY SINUSES 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.8C32 LARYNX 0.5 0.5 0.9 0.7 0.8 0.0 0.6 2.0 0.0 0.2 0.2 0.6C33 TRACHEA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0C34 BRONCHUS AND LUNG 10.4 9.5 5.4 3.8 10.8 7.3 6.2 9.5 10.0 6.7 6.7 3.7C37 THYMUS 0.2 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0C38 HEART, MEDIASTINUM, AND
PLEURA 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0C40 BONES, JOINTS AND
ARTICULAR CARTILAGE OF LIMBS 0.4 0.4 0.0 1.9 0.5 0.5 2.4 0.0 2.3 1.3 0.0 0.0
C41 BONES, JOINTS AND ARTICULAR CARTILAGE OF OTHER AND UNSPECIFIED SITES 0.1 0.8 0.4 0.0 0.4 0.7 0.0 0.2 0.0 0.0 1.2 0.0
C43 MELANOMA OF SKIN 2.9 2.3 0.7 2.2 1.8 2.1 0.9 0.6 0.6 1.8 3.9 3.9C44 OTHER SKIN 14.4 22.4 8.4 16.7 16.2 8.8 17.6 10.6 8.1 14.9 12.8 19.1C45 MESOTHELIOMA 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.7 1.4 0.0 0.0 1.1C46 KAPOSI’S SARCOMA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0C47 PERIPHERAL NERVES AND
AUTONOMIC NERVOUS SYSTEM 0.6 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 2.0 0.0 0.0
C48 RETROPERITONEUM AND PERITONEUM 0.4 1.2 0.0 0.0 0.1 0.5 0.7 0.5 0.6 1.2 0.7 1.1
AGE-ADJUSTED (WORLD STANDARD) INCIDENCE RATES OF CANCER PER 100 000CODEICD-10 SITE
DISTRICT
Sofi a city Bourgas Yambol Sliven Varna Dobrich Shoumen Veliko Tarnovo Gabrovo Pleven Lovech Vratsa
73
173.0 214.2 222.4 191.4 181.9 247.6 199.3 213.7 166.5 193.9 175.1 220.0 182.2 218.2 218.2 188.60.5 0.6 0.6 0.6 0.8 1.0 0.3 1.9 1.6 0.1 1.9 0.0 0.9 0.5 0.4 0.0
0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0
0.0 0.3 0.3 0.6 0.0 1.6 0.0 0.8 0.8 0.4 0.2 0.0 0.2 0.0 0.0 0.4
0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.7 0.1 0.0
0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.00.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0
0.0 0.6 0.2 0.0 0.6 0.0 0.0 0.8 1.3 0.4 0.0 0.0 0.2 0.0 0.0 0.0
0.0 0.2 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.3 2.0 0.0 1.2 0.9 0.2 1.0
0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0
0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0
0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0
0.0 0.0 0.6 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0
0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5
0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.0
0.0 0.1 0.3 0.8 0.7 0.0 0.6 0.0 0.0 0.3 0.2 0.0 0.4 0.5 0.7 0.0
4.0 5.7 8.9 8.8 6.0 9.8 5.8 7.8 6.5 4.9 8.2 9.5 8.2 6.2 8.8 19.0
0.0 0.0 1.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0
11.0 17.2 16.4 11.3 9.3 16.6 9.0 14.5 8.1 12.6 7.5 15.6 8.8 13.2 17.1 13.3
1.0 1.2 1.1 0.1 0.3 2.0 3.4 0.6 1.3 1.6 0.8 2.6 0.0 2.0 0.4 0.8
4.6 5.5 7.9 9.5 3.1 4.2 9.3 5.6 4.8 11.4 3.6 6.6 6.4 8.0 8.9 5.00.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0
0.0 2.4 2.8 3.3 1.2 1.9 5.0 1.8 2.9 2.7 0.4 1.9 1.3 1.9 1.1 2.61.6 1.0 0.9 0.2 0.8 2.0 1.6 1.4 1.6 0.5 0.0 2.2 0.7 2.0 1.3 0.5
0.0 0.0 0.4 0.2 0.6 0.2 0.0 0.6 0.0 0.0 0.0 1.7 0.0 0.7 0.5 2.0
4.0 3.1 5.1 3.5 9.3 3.0 5.3 3.8 5.5 5.3 4.9 4.2 5.6 5.7 4.2 3.3
0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.0 0.0 0.0
0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.00.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0
0.9 0.0 0.3 1.5 1.0 1.4 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.5 0.0
0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.07.2 9.0 6.7 4.7 3.8 8.9 4.7 8.9 8.2 7.5 8.0 8.9 2.6 7.1 8.3 10.50.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0
1.6 0.0 0.7 0.2 0.8 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0
0.0 1.1 0.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.1 0.0 1.1 0.0
0.0 0.0 0.8 0.0 1.9 0.4 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 2.2 0.0
2.0 2.0 2.6 1.4 1.4 2.3 2.0 0.8 2.7 0.5 2.6 4.7 3.6 2.1 1.2 1.0
12.6 17.8 21.2 18.2 10.0 26.4 23.9 20.6 5.1 13.4 12.1 17.3 23.5 19.6 16.9 13.0
0.0 1.2 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0
0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
0.8 1.3 0.2 0.0 0.0 1.6 2.4 2.6 0.0 1.4 0.7 3.5 0.4 0.6 0.0 0.0
Part 1BY PRIMARY SITES AND DISTRICTS IN BULGARIA 2006 - FEMALES
DISTRICT
Vidin Montana Plovdiv Pazardjik Smolyan Rousse Razgrad Silistra Targovi-shte
Sofi a district
Kyus-tendil Pernik Blagoev-
gradStara
Zagora Haskovo Kurdjali
74
C49 CONNECTIVE AND OTHER SOFT TISSUES 2.7 1.1 1.3 5.2 1.7 1.4 2.3 1.3 2.4 0.0 3.1 0.0
C50 BREAST 68.9 59.0 52.4 45.8 56.0 53.2 36.4 47.7 49.2 46.7 33.0 57.4C51 VULVA 1.8 1.1 2.2 0.4 1.1 1.1 1.1 1.5 0.0 0.8 0.9 3.0C52 VAGINA 0.3 0.6 1.3 0.0 0.5 0.3 1.2 0.7 0.0 0.5 0.0 0.6C53 CERVIX UTERI 17.2 22.8 17.1 29.3 23.4 27.2 20.2 32.2 14.4 24.1 29.7 35.6C54 CORPUS UTERI 18.2 14.2 10.5 14.5 16.7 19.1 15.3 20.5 16.3 15.6 17.9 23.2C55 UTERUS, NOS 0.2 0.8 0.0 0.0 0.1 0.6 0.0 0.8 0.6 0.1 0.0 2.2C56 OVARY 15.0 13.3 10.6 7.6 10.1 9.0 17.6 11.9 14.8 7.5 17.1 15.4C57 OTHER AND UNSPECIFIED
FEMALE GENITAL ORGANS 0.6 0.0 0.0 0.0 1.0 0.0 0.9 1.6 0.2 0.0 0.0 0.5C58 PLACENTA 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0C64 KIDNEY 4.9 4.0 8.9 2.6 1.5 1.6 3.9 2.8 3.8 2.2 2.4 2.2C65 RENAL PELVIS 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5C66 URETER 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0C67 BLADDER 6.7 4.8 1.6 3.7 5.2 3.6 1.1 1.9 1.3 1.8 2.7 3.2C68 OTHER AND UNSPECIFIED
URINARY ORGANS 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3C69 EYE AND ADNEXA 0.1 0.2 0.0 1.5 0.3 0.6 3.0 0.5 0.0 0.3 0.0 0.8C70 MENINGES 0.5 0.3 0.0 0.0 0.8 2.9 0.0 0.4 2.4 0.0 0.0 0.6C71 BRAIN 5.5 3.9 7.1 3.9 4.1 3.4 4.3 3.8 8.4 2.6 3.1 6.0C72 SPINAL CORD, CRANIAL
NERVES, AND OTHER PARTS OF CENTRAL NERVOUS SYSTEM 0.1 0.0 0.0 0.4 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0
C73 THYROID GLAND 3.4 3.3 4.2 6.2 4.8 3.1 5.9 1.6 1.6 3.6 7.2 3.2C74 ADRENAL GLAND 0.3 0.1 0.0 0.7 0.0 0.0 1.7 0.0 0.4 0.0 0.0 2.2C75 OTHER ENDOCRINE GLANDS
AND RELATED STRUCTURES 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0C76 OTHER AND ILL-DEFINED
SITES 0.1 0.1 0.0 0.0 0.4 0.5 0.0 0.0 0.3 0.0 0.0 0.0C80 MALIGNANT NEOPLASM
WITHOUT SPECIFICATION OF SITE 6.7 5.6 8.0 5.1 4.1 6.4 5.5 2.9 7.6 8.7 7.7 7.8
C81 HODGKIN’S DISEASE 1.7 1.2 0.0 0.0 1.9 0.0 0.0 0.0 8.6 1.0 1.2 0.0C82 FOLLICULAR NON-HODGKIN’S
LYMPHOMA 0.5 1.4 0.0 0.0 0.4 0.0 0.2 0.7 0.0 0.3 0.6 0.9C83 DIFFUSE NON-HODGKIN’S
LYMPHOMA 1.2 2.4 0.0 0.8 1.2 0.0 0.6 1.8 0.3 1.1 0.0 1.0C84 PERIPHERAL AND CUTANEOUS
T-CELL LYMPHOMAS 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0C85 OTHER AND UNSPECIFIED
TYPES OF NON-HODGKIN’S LYMPHOMA 1.4 1.8 0.0 2.1 0.8 1.1 0.0 0.0 0.6 1.2 0.0 0.0
C88 MALIGNANT IMMUNOPROLIFERATIVE DISEASES 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
C90 MULTIPLE MYELOMA AND MALIGNANT PLASMA CELL NEOPLASMS 1.2 1.0 0.0 1.4 0.4 1.0 0.0 0.0 1.5 1.3 0.8 1.0
C91 LYMPHOID LEUKAEMIA 3.0 2.7 1.2 8.5 1.7 2.0 7.8 1.5 0.6 0.9 0.0 0.0C92 MYELOID LEUKAEMIA 2.9 1.8 0.4 1.2 2.0 3.7 2.8 0.3 0.8 0.5 0.0 0.0C93 MONOCYTIC LEUKAEMIA 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2C94 OTHER LEUKAEMIAS OF
SPECIFIED CELL TYPE 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0C95 LEUKAEMIA, UNSPECIFIED
CELL TYPE 0.6 0.0 0.0 0.0 0.8 0.5 0.0 0.5 0.6 2.4 4.2 1.4C96 OTHER AND UNSPECIFIED
NEOPLASMS OF LYMPHOID, BLOOD FORMING AND RELATED TISSUES 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0
D06 NOT INCLUDED ABOVE CA IN SITU OF CERVIX UTERI 12.7 8.5 6.6 8.4 2.2 3.3 8.8 5.7 4.5 8.1 4.2 23.5
AGE-ADJUSTED (WORLD STANDARD) INCIDENCE RATES OF CANCER PER 100 000CODEICD-10 SITE
DISTRICT
Sofi a city Bourgas Yambol Sliven Varna Dobrich Shoumen Veliko Tarnovo Gabrovo Pleven Lovech Vratsa
75
0.0 1.6 3.3 1.0 0.0 1.6 0.4 0.0 1.4 2.5 0.6 1.8 1.8 1.1 2.8 1.9
55.5 34.6 55.9 46.9 50.7 63.0 42.8 48.9 29.5 40.2 32.3 41.8 42.8 51.3 51.6 35.60.0 3.1 1.5 1.1 0.0 1.2 2.9 3.0 0.0 0.4 1.8 1.1 1.5 0.3 1.3 1.1
0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.2 0.4 0.0 0.3 0.0 0.520.3 31.7 10.8 13.1 14.4 29.5 24.8 23.4 19.4 29.3 33.9 32.1 17.8 17.3 16.9 15.4
20.1 29.8 15.1 19.0 18.2 15.2 14.8 9.9 13.4 13.7 21.2 19.0 10.8 22.6 20.1 10.5
0.0 0.2 0.7 0.0 0.0 0.0 0.6 1.3 0.4 4.0 0.2 1.6 0.2 0.0 0.0 1.0
12.1 9.2 12.8 10.5 17.3 11.5 15.6 12.4 18.5 10.5 11.1 13.2 9.7 13.8 9.9 9.4
0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.4 0.0
0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
1.8 1.8 3.2 5.0 1.8 2.7 2.6 4.5 3.7 1.7 0.8 3.9 1.8 5.4 3.3 5.4
0.0 0.0 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.9
0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
0.3 5.0 5.0 4.0 2.1 3.2 0.7 3.7 7.0 3.4 1.6 2.2 3.3 4.6 4.4 3.4
0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
0.2 0.6 1.0 0.2 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4
0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.8 0.5 0.5 0.5 0.0
2.6 1.9 6.3 5.0 4.3 2.9 2.8 2.6 6.4 2.6 3.8 3.7 5.8 5.5 4.0 6.1
1.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.5 1.1 0.0
0.0 3.6 5.4 3.6 3.6 5.0 0.0 4.5 2.0 2.4 0.2 2.3 2.6 4.8 5.3 4.1
0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0
0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0
0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.1 1.0 0.2 0.6 0.0 0.0 0.5
2.9 6.5 4.2 3.0 4.5 10.4 6.0 7.2 5.4 5.9 5.5 1.9 3.0 5.6 5.8 4.8
0.0 0.0 2.3 2.5 0.6 2.4 4.0 1.3 0.0 1.0 0.9 4.3 1.3 0.0 0.0 1.2
0.0 0.0 0.7 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7
0.0 0.2 1.1 1.3 3.2 2.4 0.8 0.8 0.9 2.0 0.4 1.5 1.5 3.0 2.5 1.6
0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.8 0.0
1.5 0.6 2.5 0.9 0.0 2.0 2.0 1.0 0.0 3.0 1.1 0.0 1.1 0.5 0.4 0.9
0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
0.0 1.2 2.0 0.6 0.0 1.5 0.0 1.5 0.0 0.0 0.0 1.9 0.8 0.9 3.7 2.20.4 6.5 2.5 1.5 7.0 3.6 0.6 7.6 3.8 0.6 0.5 0.9 0.9 3.4 3.6 3.51.2 3.3 2.2 0.0 0.8 0.8 0.0 3.2 0.4 0.7 0.2 2.2 3.2 2.1 1.6 2.50.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0
0.0 0.9 0.2 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0
0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
6.0 7.6 3.5 5.1 3.3 9.5 7.5 2.1 4.0 8.3 5.2 8.3 5.0 16.8 6.2 1.8
Part 2BY PRIMARY SITES AND DISTRICTS IN BULGARIA 2006 - FEMALESDISTRICT
Vidin Montana Plovdiv Pazardjik Smolyan Rousse Razgrad Silistra Targovi-shte
Sofi a district
Kyus-tendil Pernik Blagoev-
gradStara
Zagora Haskovo Kurdjali
76
DISTRIBUTION OF THE NEWLY DIAGNOSED CANCER CASES BY SELECTED PRIMARY SITES AND BASIS OF DIAGNOSIS IN BULGARIA 2006
CODE ICD-9 SITE TOTAL
NUMBERCLINICAL CYTOLOGY HISTOLOGY * OTHERS AND
UNKNOWN **
DEATH CERTIFICATE
ONLYNUMBER % NUMBER % NUMBER % NUMBER % NUMBER %
140 LIP 203 - - - - 191 94.1 9 4.4 3 1.5140-149 LIP, ORAL CAVITY AND
PHARYNX 902 1 0.1 11 1.2 801 88.8 17 1.9 72 8.0151 STOMACH 1768 5 0.3 259 14.6 1213 68.6 10 0.6 281 15.9153 COLON 2487 7 0.3 168 6.8 2093 84.1 9 0.4 210 8.4154 RECTUM 1931 4 0.2 2 0.1 1677 86.8 98 5.1 150 7.8155 LIVER 660 - - 154 23.3 274 41.6 12 1.8 220 33.3150-159 DIGESTIVE ORGANS
AND PERITONEUM 8555 21 0.2 75 0.9 6136 71.7 1204 14.1 1119 13.1161 LARYNX 607 3 0.5 14 2.3 540 89.0 - - 50 8.2162 BRONCHUS, LUNG 3683 9 0.2 356 9.7 2060 55.9 800 21.8 458 12.4160-165 RESPIRATORY SYSTEM 4412 12 0.3 357 8.1 2695 61.1 828 18.7 520 11.8173 OTHER SKIN 3255 3 0.1 2 0.1 2998 92.0 246 7.6 6 0.2174 BREAST 3584 16 0.4 142 4.0 3229 90.1 110 3.1 87 2.4180 CERVIX UTERI 1208 1 0.1 9 0.7 1177 97.5 5 0.4 16 1.3182 CORPUS UTERI 1231 - - 14 1.1 1195 97.2 3 0.2 19 1.5183 OVARY ETC. 858 1 0.1 26 3.0 718 83.7 70 8.2 43 5.0185 PROSTATE 1459 3 0.2 99 6.8 1187 81.4 50 3.4 120 8.2188 BLADDER 1448 - - 76 5.2 1310 90.6 2 0.1 60 4.1179-189 GENITAL ORGANS AND
URINARY SYSTEM 7354 8 0.1 91 1.2 6545 89.1 370 5.0 340 4.6193 THYROID 263 - - 9 3.4 245 93.2 1 0.4 8 3.0
DISTRIBUTION OF THE NEWLY DIAGNOSED CANCER CASESBY SELECTED PRIMARY SITES AND STAGES IN BULGARIA 2006
CODE ICD-9 SITE TOTAL
NUMBERI STAGE II STAGE III STAGE IV STAGE WITHOUT STAGE
NUMBER % NUMBER % NUMBER % NUMBER % NUMBER %140 LIP 203 150 73.9 35 17.2 10 4.9 5 2.5 3 1.5140-149 LIP, ORAL CAVITY AND
PHARYNX 902 187 20.7 148 16.4 161 17.9 313 34.7 93 10.3151 STOMACH 1768 79 4.5 190 10.8 432 24.4 706 39.9 361 20.4153 COLON 2487 190 7.6 812 32.7 613 24.6 598 24.1 274 11.0154 RECTUM 1931 192 9.9 653 33.9 481 24.9 390 20.2 215 11.1155 LIVER 660 3 0.5 24 3.6 101 15.3 255 38.6 277 42.0150-159 DIGESTIVE ORGANS
AND PERITONEUM 8555 506 5.9 1805 21.1 1918 22.4 2834 33.1 1492 17.5161 LARYNX 607 53 8.7 97 16.0 144 23.7 247 40.7 66 10.9162 BRONCHUS, LUNG 3683 124 3.4 248 6.7 1451 39.4 1303 35.4 557 15.1160-165 RESPIRATORY SYSTEM 4412 180 4.1 357 8.1 1626 36.8 1592 36.1 657 14.9173 OTHER SKIN 3255 2551 78.4 590 18.1 76 2.3 12 0.4 26 0.8174 BREAST 3584 903 25.2 1669 46.6 667 18.6 217 6.0 128 3.6180 CERVIX UTERI 1208 489 40.5 308 25.5 322 26.6 36 3.0 53 4.4182 CORPUS UTERI 1231 761 61.8 212 17.2 130 10.6 47 3.8 81 6.6183 OVARY ETC. 858 192 22.4 107 12.5 327 38.1 159 18.5 73 8.5185 PROSTATE 1459 135 9.2 574 39.3 333 22.8 253 17.3 164 11.2188 BLADDER 1448 481 33.2 543 37.5 224 15.5 98 6.8 102 7.0179-189 GENITAL ORGANS AND
URINARY SYSTEM 7354 2300 31.3 2063 28.0 1595 21.7 784 10.7 612 8.3193 THYROID 263 98 37.3 81 30.8 44 16.7 23 8.7 17 6.5
* Histology included: histology of a primary tumor, and histology of a metastasis** Others included: clinical investigations, and specifi c tumor markers
77
DISTRIBUTION OF THE NEWLY DIAGNOSED CANCER CASES BY SELECTED PRIMARY SITES, STAGES AND DISTRICTS IN BULGARIA 2006
DISTRICT
FEMALE BREAST CERVIX UTERI PROSTATETOTAL I+II
STAGEIII+IV
STAGEWITHOUT
STAGETOTAL I+II
STAGEIII+IV
STAGEWITHOUT
STAGETOTAL I+II
STAGEIII+IV
STAGEWITHOUT
STAGENUMBER % % % NUMBER % % % NUMBER % % %
BLAGOEVGRAD 116 74.1 24.1 1.7 39 64.1 33.3 2.6 53 17.0 75.5 7.5
BOURGAS 209 78.0 20.6 1.4 68 73.5 26.5 - 69 71.0 27.5 1.4
YAMBOL 63 73.0 22.2 4.8 20 70.0 30.0 - 27 59.3 37.0 3.7
VARNA 215 81.9 14.4 3.7 79 74.7 20.3 5.1 97 37.1 57.7 5.2
DOBRICH 96 70.8 21.9 7.3 42 76.2 19.0 4.8 18 16.7 55.6 27.8VELIKO TURNOVO 121 66.9 33.1 - 64 60.9 37.5 1.6 53 62.3 28.3 9.4
GABROVO 72 72.2 27.8 - 18 66.7 33.3 - 27 55.6 33.3 11.1
VRATSA 120 54.2 30.8 15.0 50 72.0 14.0 14.0 53 43.4 30.2 26.4
VIDIN 69 56.5 33.3 10.1 18 61.1 11.1 27.8 14 28.6 14.3 57.1
MONTANA 56 55.4 30.4 14.3 34 47.1 14.7 38.2 36 44.4 8.3 47.2
PLEVEN 147 68.7 31.3 - 58 72.4 27.6 - 48 29.2 70.8 -
LOVECH 51 76.5 23.5 - 37 75.7 24.3 - 31 58.1 38.7 3.2
PLOVDIV 351 71.8 26.5 1.7 59 71.2 28.8 - 172 50.6 46.5 2.9
PAZARDJIK 121 66.9 33.1 - 26 76.9 23.1 - 45 42.2 53.3 4.4
SMOLYAN 55 67.3 32.7 - 11 72.7 27.3 - 21 28.6 71.4 -
ROUSSE 143 76.2 21.7 2.1 55 67.3 30.9 1.8 33 33.3 51.5 15.2
RAZGRAD 49 69.4 24.5 6.1 25 64.0 20.0 16.0 12 41.7 41.7 16.6
SILISTRA 58 69.0 25.9 5.2 22 72.7 13.6 13.6 16 31.3 56.3 12.5
SOFIA SITY 746 75.9 18.9 5.2 169 59.2 38.5 2.4 293 67.9 21.8 10.2
SOFIA DISTRICT 103 68.9 31.1 - 52 61.5 36.5 1.9 54 50.0 29.6 20.4
KYUSTENDIL 52 71.2 26.9 1.9 34 67.6 32.4 - 35 48.6 42.9 8.6
PERNIK 63 73.0 27.0 - 36 75.0 22.2 2.8 37 32.4 45.9 21.6
STARA ZAGORA 169 66.3 33.1 0.6 49 55.1 44.9 - 69 34.8 60.9 4.3
SLIVEN 78 70.5 28.2 1.3 43 67.4 32.6 - 28 39.3 53.6 7.1
HASKOVO 117 73.5 22.2 4.3 35 68.6 25.7 5.7 45 51.1 35.6 13.3
KURDJALI 43 72.1 18.6 9.3 18 27.8 55.6 16.7 22 40.9 31.8 27.3
SHOUMEN 65 64.6 32.3 3.1 28 60.7 39.3 - 30 40.0 30.0 30.0
TURGOVISHTE 36 72.2 16.7 11.1 19 52.6 42.1 5.3 21 28.6 42.8 28.6
78
CODE ICD-10 SITE NUMBER
MALE CRUDE DATA
100 000
% NUMBER
FEMALE CRUDE DATA
100 000
% NUMBER
TOTAL CRUDE DATA
100 000
% CODE ICD 9
C00-C97 ALL SITES 102061 2734.7 100.0 146560 3694.6 100.0 248621 3229.3 100.0 140-208
C00-C14 LIP, ORAL CAVITY AND PHARYNX 7035 188.5 6.9 2327 58.7 1.6 9362 121.6 3.8 140-149
C00 LIP 4639 124.3 4.5 1174 29.6 0.8 5813 75.5 2.3 140
C15-C26 DIGESTIVE ORGANS 19833 531.4 19.4 16559 417.4 11.3 36392 472.7 14.6 150-157, 159
C15 ESOPHAGUS 343 9.2 0.3 133 3.4 0.1 476 6.2 0.2 150
C16 STOMACH 3610 96.7 3.5 2330 58.7 1.6 5940 77.2 2.4 151
C18 COLON 7120 190.8 7.0 6934 174.8 4.7 14054 182.5 5.7 153
C19-C21 RECTUM AND ANUS 6174 165.4 6.0 5031 126.8 3.4 11205 145.5 4.5 154
C22LIVER AND INTRAHEPATIC BILE DUCTS 683 18.3 0.7 475 12.0 0.3 1158 15.0 0.5 155
C25 PANCREAS 1333 35.7 1.3 1039 26.2 0.7 2372 30.8 1.0 157
C30-C39RESPIRATORY SYSTEM AND INTRATHORACIC ORGANS 13644 365.6 13.4 2455 61.9 1.7 16099 209.1 6.5 160-165
C32 LARYNX 4664 125.0 4.6 329 8.3 0.2 4993 64.9 2.0 161
C33,C34 TRACHEA, BRONCHUS AND LUNG 8570 229.6 8.4 1893 47.7 1.3 10463 135.9 4.2 162
C40-C41BONES, JOINTS AND ARTICULAR CARTILAGE OF LIMBS 435 11.7 0.4 378 9.5 0.3 813 10.6 0.3 170
C43-C44 SKIN 27097 726.0 26.5 26973 679.9 18.4 54070 702.3 21.8 172, 173
C43 MELANOMA OF SKIN 1500 40.2 1.5 1795 45.2 1.2 3295 42.8 1.3 172
C45-C49MESOTHELIAL, CONNECTIVE AND OTHER SOFT TISSUES 1373 36.8 1.3 1362 34.3 0.9 2735 35.5 1.1 158, 163, 171
C50 BREAST 363 9.7 0.4 43362 1093.1 29.5 43725 567.9 17.7 174, 175
C51-C58 FEMALE GENITAL ORGANS - - - 38553 971.9 26.3 38553 500.8 15.5 179-184
C53 CERVIX UTERI - - - 13483 339.9 9.2 13483 175.1 5.4 180
C54 CORPUS UTERI - - - 16559 417.4 11.3 16559 215.1 6.7 182
C55 UTERUS, NOS - - - 248 6.2 0.2 248 3.2 0.1 179
C56 OVARY - - - 6598 166.3 4.5 6598 85.7 2.7 183.0
C60-C63 MALE GENITAL ORGANS 12441 333.3 12.2 - - - 12441 161.6 5.0 185-187
C61 PROSTATE GLAND 9097 243.7 8.9 - - - 9097 118.2 3.7 185
C64-C68 URINARY TRACT 10264 275.0 10.1 3768 95.0 2.6 14032 182.3 5.6 188-189
C67 BLADDER 7714 206.7 7.6 2024 51.0 1.4 9738 126.5 3.9 188
C69-C72EYE, BRAIN AND OTHER PARTS OF CENTRAL NERVOUS SYSTEM 1675 44.9 1.6 1603 40.4 1.1 3278 42.6 1.3 190-192
C69 EYE AND ADNEXA 288 7.7 0.3 284 7.2 0.2 572 7.4 0.2 190
C71 BRAIN 1236 33.1 1.2 1109 28.0 0.8 2345 30.5 0.9 191
C73-C75THYROID AND OTHER ENDOCRINE GLANDS 817 21.9 0.8 3177 80.1 2.2 3994 51.9 1.6 193-194
C73 THYROID GLAND 709 19.0 0.7 3071 77.4 2.1 3780 49.1 1.5 193
C76-C80 OTHER AND ILL-DEFINED SITES 1991 53.3 2.0 1607 40.5 1.1 3598 46.7 1.4 195-199
C81-C96LYMPHATIC AND BLOOD-FORMING TISSUES 5093 136.5 5.0 4436 111.8 3.0 9529 123.8 3.8 200-208
C81 HODGKIN’S DISEASE 1196 32.0 1.2 998 25.2 0.7 2194 28.5 0.9 201
C82-C85 NON-HODGKIN’S LYMPHOMAS 1357 36.4 1.3 1272 32.1 0.9 2629 34.1 1.1 200, 202
C91-C95 LEUKAEMIA 1894 50.7 1.9 1631 41.1 1.1 3525 45.8 1.4 204-208
C91 LYMPHOID LEUKAEMIA 981 26.3 1.0 776 19.6 0.5 1757 22.8 0.7 204
C92 MYELOID LEUKAEMIA 574 15.4 0.6 498 12.6 0.3 1072 13.9 0.4 205
CANCER PREVALENCE IN BULGARIA 2006DISTRIBUTION BY PRIMARY SITE AND SEX
79
CODEICD-10 SITE NUMBER
MALES CRUDE
DATA 100 000
% NUMBER
FEMALESCRUDE
DATA 100 000
% NUMBER
TOTAL CRUDE
DATA 100 000
%
C00-97 ALL SITES 10271 275.2 100.0 7278 183.5 100.0 17549 227.9 100.0C00 LIP 20 0.5 0.2 9 0.2 0.1 29 0.4 0.2C01-02 TONGUE 138 3.7 1.3 51 1.3 0.7 189 2.5 1.1C03-06 MOUTH 53 1.4 0.5 17 0.4 0.2 70 0.9 0.4C07-08 SALIVARY GLANDS 28 0.8 0.3 9 0.2 0.1 37 0.5 0.2C09 TONSIL 23 0.6 0.2 2 0.1 0.0 25 0.3 0.1C10 OTHER OROPHARYNX 23 0.6 0.2 8 0.2 0.1 31 0.4 0.2C11 NASOPHARYNX 24 0.6 0.2 3 0.1 0.0 27 0.4 0.2C12-13 HYPOPHARYNX 60 1.6 0.6 17 0.4 0.2 77 1.0 0.4C14 PHARYNX UNSPECIFIED 30 0.8 0.3 10 0.2 0.1 40 0.5 0.2C15 OESOPHAGUS 156 4.2 1.5 38 1.0 0.5 194 2.5 1.1C16 STOMACH 910 24.4 8.9 626 15.8 8.6 1536 20.0 8.8C17 SMALL INTESTINE 32 0.9 0.3 7 0.2 0.1 39 0.5 0.2C18 COLON 793 21.2 7.7 625 15.8 8.6 1418 18.4 8.1C19-21 RECTUM AND ANUS 602 16.1 5.9 423 10.7 5.8 1025 13.3 5.8C22 LIVER 583 15.6 5.7 363 9.2 5.0 946 12.3 5.4
C23-24GALLBLADDER AND EXTRAHEPATIC BILE DUCTS 53 1.4 0.5 87 2.2 1.2 140 1.8 0.8
C25 PANCREAS 520 13.9 5.1 379 9.6 5.2 899 11.7 5.1C30-31 NOSE, SINUSES 22 0.6 0.2 8 0.2 0.1 30 0.4 0.2C32 LARYNX 368 9.9 3.6 20 0.5 0.3 388 5.0 2.2C33-34 TRACHEA, BRONCHUS, LUNG 2777 74.4 27.0 560 14.1 7.7 3337 43.3 19.0C37-38 OTHER THORACIC ORGANS 27 0.7 0.3 22 0.6 0.3 49 0.6 0.3C40-41 BONE 71 1.9 0.7 47 1.2 0.6 118 1.5 0.7C43 MELANOMA OF SKIN 90 2.4 0.9 69 1.7 1.0 159 2.1 0.9C44 OTHER SKIN 77 2.1 0.8 44 1.1 0.6 121 1.6 0.7C45 MESOTHELIOMA 1 0.0 0.0 2 0.1 0.0 3 0.0 0.0C46 KAPOSI’S SARCOMA 3 0.1 0.0 4 0.1 0.1 7 0.1 0.0C47,C49 CONNECTIVE AND SOFT TISSUE 8 0.2 0.1 17 0.4 0.2 25 0.3 0.1C50 BREAST 29 0.8 0.3 1245 31.4 17.2 1274 16.5 7.2C51 VULVA - - - 55 1.4 0.8 55 0.7 0.3C52 VAGINA - - - 17 0.4 0.2 17 0.2 0.1C53 CERVIX UTERI - - - 335 8.4 4.6 335 4.4 1.9C54 CORPUS UTERI - - - 271 6.8 3.7 271 3.5 1.5C55 UTERUS UNSPECIFIED - - - 178 4.5 2.4 178 2.3 1.0C56 OVARY - - - 447 11.3 6.1 447 5.8 2.6C57 OTHER FEMALE GENITAL ORGANS - - - 31 0.8 0.4 31 0.4 0.2C58 PLACENTA - - - - - - - - -C60 PENIS 18 0.5 0.2 - - - 18 0.2 0.1C61 PROSTATE 799 21.4 7.8 - - - 799 10.4 4.6C62 TESTIS 51 1.4 0.5 - - - 51 0.7 0.3C63 OTHER MALE GENITAL ORGANS 4 0.1 0.0 - - - 4 0.1 0.0C64 KIDNEY 222 5.9 2.2 96 2.4 1.3 318 4.1 1.8C65 RENAL PELVIS 8 0.2 0.1 3 0.1 0.0 11 0.1 0.1C66 URETER 9 0.2 0.1 12 0.3 0.2 21 0.3 0.1C67 BLADDER 387 10.4 3.8 115 2.9 1.6 502 6.5 2.9C68 OTHER URINARY ORGANS 9 0.2 0.1 4 0.1 0.1 13 0.2 0.1C69 EYE 9 0.2 0.1 9 0.2 0.1 18 0.2 0.1C70-72 BRAIN, NERVOUS SYSTEM 368 9.9 3.6 278 7.0 3.8 646 8.4 3.7C73 THYROID 22 0.6 0.2 34 0.9 0.5 56 0.7 0.3C74 ADRENAL GLAND 13 0.3 0.1 13 0.3 0.2 26 0.3 0.2C75 OTHER ENDOCRINE GLANDS 1 0.0 0.0 7 0.2 0.1 8 0.1 0.1C81 HODGKIN’S DISEASE 48 1.3 0.5 28 0.7 0.4 76 1.0 0.4C82-85, C96 NON-HODGKIN’S LYMPHOMA 122 3.3 1.2 95 2.4 1.3 217 2.8 1.2C88 IMMUNOPROLIFERATIVE DISEASES 2 0.1 0.0 1 0.0 0.0 3 0.0 0.0C90 MULTIPLE MYELOMA 48 1.3 0.5 40 1.0 0.6 88 1.1 0.5C91 LYMPHOID LEUKAEMIA 94 2.5 0.9 53 1.3 0.7 147 1.9 0.8C92 MYELOID LEUKAEMIA 91 2.4 0.9 71 1.8 1.0 162 2.1 0.9C93 MONOCYTIC LEUKAEMIA 1 0.0 0.0 1 0.0 0.0 2 0.0 0.0C94 OTHER LEUKAEMIAS 11 0.3 0.1 16 0.4 0.2 27 0.4 0.2C95 LEUKAEMIA UNSPECIFIED 39 1.0 0.4 29 0.7 0.4 68 0.9 0.4C26,C39, C48, C76, C80
OTHERS AND UNSPECIFIED SITES341 9.1 3.3 304 7.7 4.2 645 8.4 3.7
C00-97 BUT C44
ALL SITES BUT NON-MELANOMA SKIN 10194 273.1 99.2 7234 182.4 99.4 17428 226.4 99.3
CANCER MORTALITY IN BULGARIA 2006DISTRIBUTION OF DEATHS BY PRIMARY SITES AND SEX
80
ÁÚÐÇÎ ÈÇÂÅÑÒÈÅ
çà çàäúëæèòåëíî ñúîáùàâàíå çà çëîêà÷åñòâåíî çàáîëÿâàíå
1. Çäðàâíîçàâåäåíèå
2. Ïîðåäåí № 3. Ñúîá-ùàâàñå:
ñúìíèòåëåííîâîçàáîëÿëïî ñìúðò. àêòîòêðèò ïðè àóòîï.
1234
4. ÏîëÌ
Æ
5. Âúçðàñò1 3
121098
13
3547
34
56
6157
62 64
65
66
68
6972
73 76
77 78 79 81
82
83 87
88 91
6. Èìå
7. Ìåñòîæèòåëñòâî
8. Ñåìååí ñòàòóñ
ñîá.
ôàì.
áàù.
ÅÃÍ
íàñåëåíîìÿñòî
îáùèíà
îáëàñò
9. Àäðåñ:
10. Ìåñòîðàáîòà:
11. Ïðîôåñèÿ:
12. Ñîöèàëíà ãðóïà:
13. Êëèíè÷íà äèàãíîçà:
14. Êëèíè÷íà êëàñèôèêàöèÿ:(ïðè îïåðàöèÿ - ñëåä îïåðàòèâíàòà)
15. Íà÷èí íà äîêàçâàíå:
16. Ìîðôîëîãè÷íà äèàãíîçà:
17. Ïîñòàâåíà â:(çäð. çàâåäåíèå)
Äàòà Ïîïúëíèë:èìå, ôàìèëèÿ
1
2
3
4
5
9
íåæåíåí
æåíåí
ðàçâåäåí
ðàçäåëåí
âäîâåö
íåïîêàç.
ãð. ñ.
ÌÊÁ
íà äàòà
T N M ñòàäèé
ÌÊÁ
íà äàòà
67
àóòîïñèÿ áåç õèñò.àóòîïñèÿ ñ õèñòîë.3
45
öèòîëîãè÷íîõèð. èíòåðâ. áåç õèñòîë.
õèð. èíòåðâ. ñ õèñòîë.12
êëèíè÷íî
ðåíòãåíîëîã.
(ï)
Áë. ÌÍÇ åêñï. ‘89
1. Health establishment; 2. Registration number; 3. Notify: suspected, newly cases, death certifi cate, cases found incidentally at autopsy; 4. Sex; 5. Age;
6.Name, Personal Identifi cation Number; 7.Place of residence; 8. Marital status; 9. Address; 10. Place of work; 11. Occupation;
12. Social class; 13. Clinical diagnosis; 14. TNM system and stage; 15. Most valid basis of diagnosis; 16. Morphological diagnosis; 17. Notifi ed by… and date
RAPID NOTIFICATION:
(îáñëóæâàù îíê. äèñïàíñåð)
ì ãîä.
89
äðóãè ìåòîäèíåïîñî÷åíî
ì ãîä.
