Path WaysThe Johns Hopkins Medical Institutions Depatment of Pathology Volume 5, Issue 1, February, 2001

Dr. Fred Sanfilippo accepted the position ofS r. Vice President for Health Sciences and

Dean, College of Medicine and Public Health atOhio State University effective September 1,2000. While we were sorry to see him go, this isa great opportunity for him. From all reports,he is thoroughly enjoying the challenges facinghim at Ohio State.

Brooks Jackson Named Interim Director of PathologyIn the meanwhile, we are all pleased that

J. Brooks Jackson, M.D., M.B.A., has beennamed Interim Director of the Department andPathologist-in-Chief of the Hospital. D r. Jackson was recruited by Dr. Sanfilippo in1996 from Case Western Reserve University asProfessor and Deputy Director for ClinicalAffairs. Dr. Jackson was Director of ClinicalP a t h o l o g y, Institute of Pathology at UniversityHospitals of Cleveland from 1989-1996. Hereceived a B.A. in History from Kenyon College,G a m b i e r, Ohio, an M.B.A. from the Amos Tu c kSchool of Business Administration atDartmouth College, followed by an M.D. fromDartmouth Medical School. He trained inClinical Pathology and Transfusion Medicine atthe University of Minnesota Hospitals in theDepartment of Laboratory Medicine and Path-

J.Brooks Jackson (left) and Fred Sanfilippo (right)

Director’sCorner

It gives me great pleasure to reactivate theP a t h Ways Newsletter. As our Department

continues to grow, communication becomesincreasingly more important yet more difficultas we are spread ever wider, not just on campus,but around the globe. I strongly encouragePathology faculty, housestaff, students, and staffat all of our sites to contribute to this Newsletter.

This past year has obviously been one oftransition with Dr. Sanfilippo’s departure, but Iwant to assure everyone in Pathology that weare doing well by almost any measure. Ourclinical services continue to grow with the addi-tion of new assays and our expansion to theWhite Marsh Clinic this past year. Laboratory

J. Brooks Jackson

Continued on page 2

The Division of Gastrointestinal/LiverPathology was one of the first and is per-

haps the longest standing Gastrointestinal/LiverPathology Division in the country. The Divisionhas an extraordinarily rich history of creativeresearch, diagnostic excellence, and quality fel-l o w, resident and medical student education. Inmany ways, the Division is a microcosm of thebreadth and depth of excellence in the broaderDepartment.

The h i s t o r y of the Division encompassesthe long careers of Drs. Yardley and Boitnott atJohns Hopkins. Dr. Ya r d l e y ’s GI interests beganwith collaborative studies on inflammatorybowel disease with Drs. Tom Hendrix and Te dBayless and ultimately grew into a formal fel-lowship training program, which has trained 22fellows since 1963. Dr. Boitnott’s interest in liverbegan during his housestaff training with asummer spent with Dr. Jerry Klatskin at Ya l e ,

followed by collaborations at Hopkins with Drs.Frank Iber, Willis Maddrey and Frank Herlong.

C u r r e n t l y, there are eleven faculty mem-bers with a primary appointment in theDivision and three additional faculty memberswith secondary appointments. The Division isheaded by Dr. Ralph Hruban, who is also one ofthe Vice-Chairs of the Department. Other mem-bers of the Division include Drs. John Ya r d l e y,John Boitnott, Belur Bhagavan, JamesEshleman, Elizabeth Montgomery, Ts u n g - Te hWu, Susan Abraham, Michael Goggins, GloriaSu, and our newest faculty member, RobbWilentz. Faculty with a secondary appointmentin the Division include Drs. Bert Vo g e l s t e i n ,Scott Kern, and Elizabeth Jaffee.

The r e s e a r c h interests of the Division arebroad, however, they primarily focus on gas-trointestinal malignancies. The research labo-

Division in Highlight: Gastrointestinal/Liver Pathology

Continued on page 3

o l o g y. Dr. Jackson's research focuses on preven-tion, diagnosis and treatment of HIV infection.He currently runs several successful clinical tri-als and operates research laboratories inBaltimore, Uganda, and China. Recently, hereported that oral nevirapine can significantlyreduce infant maternal transmission of HIV.(Lancet 1999; 354:803-809)

A search committee has been named byDean Miller to identify and recommend candi-dates for a new director. The process is wellunderway and involves seminar presentationsby the candidates, meetings with senior leader-ship of the School and the Department, and theinvolvement of the majority of the faculty whena "short-list" is identified. It is anticipated thata candidate will be named this Spring. n

Page 2

testing volume and pro fee billing are at an alltime high, and we are expecting to meet orimprove on our budgeted revenues and expens-es for the Hospital and Clinical PracticeAssociation this year. Our medical consultationservices and international research and trainingprojects have also expanded significantly thisyear with projects in Abu Dhabi, Brazil, Dubai,Singapore, China, Uganda, and Saudi Arabia.These projects are not only financially attractivefor the Department, but also offer a number ofopportunities for research and teaching. Thispast year Congress and NIH in particular haveset aside significant sums of funding for inter-national research and training grants. I en-courage interested faculty to take advantage ofthese opportunities using the infrastructure andrelationships we are developing at these sites.

At the same time, we have seen continuedsuccess in our educational mission. The qualityof the applicants applying to our ResidencyTraining Program and Pathobiology GraduateStudent Program has never been better. We areplanning to accept 7 residents in the matchprogram this year bringing the total to 31 resi-dents in our 4-year program for next year. Inthe Pathobiology Graduate Student Program weare planning to accept 4 graduate studentswhich will bring our total to 12. The secondyear medical school course will be infused witha significant technology upgrade in the nexty e a r, and the popularity of our elective precep-torship for medical students has never beenh i g h e r. We are also adding fellowship slots inthe areas of hematopathology, genito-urinaryp a t h o l o g y, and renal pathology funded in largepart by philanthropic gifts and increased out-side consultation fees. The popularity of ourCME activities continues to grow as evidencedby an all time attendance high at the annualJHU G-2 workshop this past Fall, and we areexpecting an even greater number of registrantsat the cytopathology, surgical pathology, andlaboratory medicine courses this Spring.Corporate support for our web-based education-

Continued from page 1 al activities has also increased significantly thispast year, providing multiple opportunities forfaculty to develop innovative teaching pro-g r a m s .

On the research side of our department, Iam especially proud to report that our NIHfunding for the government fiscal year 2000(Oct 99-Sept 00) increased 54% from$13,298,277 to $20,487,391 from the yearbefore. Although the NIH has not yet releasedthe national rankings of PathologyDepartments in terms of NIH funding, I expectthat we will move up in the national rankingfrom a ranking of 5th the year before. Thenumber of different Pathology faculty asPrincipal Investigators of NIH grants and con-tracts has also increased from 27 to 31 this pastyear indicating the growing breadth and depthof the Department. With the NIH budget expect-ed to double over the next several years and thestrong economic growth in the biotech/phar-maceutical industry, we can expect major op-portunities for our faculty, fellows, and graduatestudents. Corporate sponsored research for ourdepartment will be approximately $3 millionthis year with an additional $350,000 in supportfrom licensing fees and royalties.

The biggest challenge we face is acquiringthe needed space to carry out these activities.Over the next several years the institution hasplans to greatly expand the campus in terms ofland, hospital buildings, research facilities, andparking garages. However, in the short term,space will be very tight. Therefore, it will benecessary to utilize space on off shifts as muchas possible, share space where feasible, and con-sider offsite space for suitable projects.H o p e f u l l y, we will acquire some space immedi-ately with the selection of a new DepartmentD i r e c t o r.

In the meantime, I think that we truly dohave the best Pathology Department in thecountry and that we will continue to have anincreasingly greater impact in research, teach-ing, and patient care in our field. n

Director’s Corner

Annual EmployeeAppreciation Day

The Annual Employee Appreciation Day(date to be announced) will be held in

conjunction with Lab Week this year. Pleasejoin the Department of Pathology at TheMaryland Science Center for an evening of dis-c o v e r y. This will be a catered event for employ-ees and their immediate families in recognitionof a tremendous year. Special amenities willinclude the Davis Planetarium, the BoydT h e a t e r, home of the laser light show, and anevening of music and dancing. More details tof o l l o w. n

You are invited to join us at theJohns Hopkins Pathology

Alumni Receptionat the USCAP Meeting

M o n d a y, March 5th5:30 pm - 7:30 pmConsulate Room

Atlanta Marriott Marquis265 Peachtree Center Av e n u e

Atlanta, Georgia

The Maryland Science Center

Page 3

ratories of Drs. Hruban, Goggins, Su, Kern, andJaffee are focused on the pathobiology of pan-creatic cancer. Dr. Hruban studies familial pan-creatic cancer (he founded the NationalFamilial Pancreas Tumor Registry) and the pre-cursors to invasive pancreatic cancer. Dr.Hruban will be awarded the Young InvestigatorAward at the March meeting of the United Statesand Canadian Academy of Pathology for thiswork. Dr. Goggins is a gastroenterologist bytraining. His efforts are directed toward devel-oping an early detection test for pancreatic can-c e r. Dr. Su is developing new animal models ofpancreatic cancer. Using "conditional knock-out" technology, she will recreate the moleculargenetic alterations identified in human cancersin a mouse model. These laboratories are gen-erously supported by the family and friends ofMichael Rolfe (see page 6). All three investiga-tors collaborate extensively with Drs. Scott Kern,Elizabeth Jaffee, and Johan Offerhaus. Scott hasmade most of the fundamental genetic discov-eries in the field of pancreatic cancer, includingthe discovery of the DPC4 gene and and Liz hasdeveloped a novel vaccine to treat pancreaticc a n c e r. Johan has been a long-term participantin the Bowel Tumor Working Group at JohnsHopkins and he has organized numerous scien-tific collaborations and fellow exchangesbetween the group at Hopkins and the GIpathology group in Amsterdam.

Drs. Eshleman and Montgomery study col-orectal neoplasia. Dr. Eshleman’s laboratory isinvestigating the role of defects in DNA repair in

Continued from page 1

Division in Highlight: Gastrointestinal/Liver Pathology

colon carcinogenesis. He is also involved intranslational research in the molecular diag-nostics laboratory and is an active member ofthe Bowel Tumor Working Group. Dr.Montgomery collaborates extensively with Dr.Bert Vogelstein providing much needed collabo-rative expertise in the pathology of the tumorsstudied in the Vogelstein laboratory. Our col-orectal neoplasia group will be expanded in Julywith the addition of Dr. Robb Wilentz. Robb wasan extraordinarily productive resident in ourprogram. He will join the faculty in July andstudy the molecular genetic basis of dysplasia inpatients with inflammatory bowel disease.

Drs. Susan Abraham and Ts u n g - Teh Wuform an active collaboration studying thegenetic alterations in gastric and esophagealneoplasms, including fundic gland polyps ofthe stomach and adenocarcinomas arising inthe setting of Barrett's esophagus. In addition,D r. Abraham is currently collaborating with Dr.Scott Kern on his studies of the moleculargenetics of pancreatic neoplasia.

The Division's three senior members partic-

ipate in a variety of clinical pathologic correla-tion research projects. Dr. John Yardley is revis-ing a popular teaching series with Dr. Hendrixfor the American Gastrointestinal Association.D r. John Boitnott, as always, provides a breadthand depth of expertise in liver pathology as wellas avuncular wisdom and advice, and Dr. BelurBhagavan has a broad range of interests, butfocuses his efforts on pediatric GI pathology.

Under the leadership of Dr. Montgomery,the d i a g n o s t i c service continues to grow. Lasty e a r, members of the Division examined biop-sies from over 7,500 patients. Difficult cases arereviewed at a weekly diagnostic GI pathologyconference and interesting cases are often pre-sented on the Web through the SurgicalPathology Web site ( h t t p : / / p a t h o l o g y 2 . j h u . e d u / s p ) .

Te a c h i n g has always been the cornerstoneof Divisional activities. Numerous research fel-lowships are offered, as well as a two-year com-bined clinical-research fellowship. The latterfellowship provides a unique opportunity for fel-lows to become world-class diagnosticians andresearchers. This fellowship program was for-mally started in 1983 with crucial support fromthe Meyerhoff Fund (Harvey & Lyn Myerhoff)and the Clayton Fund (Ben & Julia ClaytonBaker). The quality of this program can be seenin our current applicant pool (we typically havebetween 10-20 applicants for each fellowshipposition) and by the numerous awards the fel-lows have received from the GastrointestinalPathology Society and at the Department'sAnnual Young Investigator Day. The long-termvitality of this combined fellowship is nowassured with the creation of the John Ya r d l e y

Gloria Su

left to right, Michael Goggins, Ralph Hruban, TT Wu, Susan Abraham, Jack Yardley, Elizabeth Montgomery ,Michael Torbenson and Belur Bhagavan. Continued on page 5

Antony Parker and Jim Eshleman

Rene Galindo, M.D., Ph.D.

Rene is the next gen-eration of patholo-

gists to join us fromSouthwestern in Te x a s .Prior to his M.D., hereceived his Ph.D. in theGenetics andDevelopment GraduateProgram atSouthwestern. His undergraduate degree isfrom St. Mary’s University is San Antonio. Renehas an avid interest in cinema and also enjoystennis, golf, and skiing. More recently, he hasbegun pursuing photography as a hobby.

Kimmo Hatanpää, M.D., Ph.D.

Kimmo received hismedical degree at

the University ofTampere, Finland. Hecontinued at Ta m p e r eMedical School andreceived his Ph.D. study-ing neuronal dysfunc-tion and Alzheimer’s

Disease. For much of his graduate study,Kimmo was a Fogarty Visiting Fellow at NIHand during his last year was the Chief of theMolecular Neuropathology Unit. Following hisPh.D., he did two years of residency in anatomicpathology at Yale University School of Medicineand joins us to complete his AP/NP training.

Lori Iaconis, M.D.

Lori received her u n d e r g r a d u a t e

degree from IndianaUniversity ofPennsylvania and herM.D. degree fromHoward UniversityCollege of Medicine inWashington, DC. Shecompleted summer Medical Student Fellowship

in Pathology in Providence Hospital inWashington, DC. Lori participated in volunteerhealthcare programs providing gynecologiccare, childhood vaccinations and organizingadult health fairs. Her interests outside patholo-gy include running.

Walter Klein, M.D.

Walter comes toBaltimore from

Philadelphia where heearned his M.D. at theUniversity ofPennsylvania. He stud-ied chemistry as anundergraduate at theUniversity of Pittsburgh

as well as spending a year of college in Englandat the University of Sussex. He has beeninvolved in oncogene research and in thesearch for a tumor suppressor gene on the shortarm of chromosome 9. Walter has participatedin intramural basketball and soccer.

Saeid Movahedi-Lankarani, M.D.

Saeid completed hisB.Sc. degree in

M i c r o b i o l o g y, andMolecular and CellularBiology at the Universityof Arizona. He receivedhis M.D. degree fromOregon Health SciencesU n i v e r s i t y, where he alsocompleted a post-sopho-more fellowship in pathology. During medicalschool, he was involved in tutoring junior med-ical students and acted as an instructor in aprogram for minority elementary school chil-dren. He enjoys ancient Near Eastern historyand archeology, basketball, coin collecting andblues music.

Robert Law, M.D.

Robert received hisB.Sc. degree in

Biology and Chemistryand subsequently hisM.D. degree from theUniversity of Alabamaat Birmingham. Hisresearch experienceincludes investigatingthe role of phosphorylation in functional regu-lation of GABA uptake, studying signal trans-duction pathways in endothelial cells and theexamination of nervous/immune system inter-actions. Robert is interested in neurosciences.

Eric Lee Powell, M.D.

Eric completed his u n d e r g r a d u a t e

degree at IndianaUniversity inIndianapolis and hisM.D. degree at IndianaUniversity School ofMedicine. In his thesishe studied the identifi-

cation of antigens of free-living parasitic amoe-bae by protein immunoblotting. He spent sev-eral months in Senegal with the Peace Corps asa community health consultant, where he tookpart in projects such as oral rehydration thera-p y, pediatric vaccination and malaria preven-tion. He is joining the program with interest inmolecular diagnostics.

Greg Seidel, M.D.

As an undergraduate, Greg studied

Psychobiology atTulane. From there, hewent to medical schoolat the Medical Collegeof Ohio. During the lasty e a r, he has been inves-tigating low hemoglobin A1c in patients withuncontrolled type I diabetes and renal insuffi-ciency during pregnancy. Besides being trainedas an EMT, Greg plays volleyball, enjoys runningand backpacking, and is a music enthusia s t .

Page 4

Department of Pathology New Residents, 2000-2001

Page 5

Fellowship in Gastrointestinal Pathology. Wethank all of you who have honored the contri-butions of Dr. Yardley by supporting the creationof this fellowship.

Divisional teaching activities extend beyondthe fellowship programs and recently haveincluded a number of Web-based initiatives. Asdescribed in greater detail on page 11, theDivision hosts a number of disease-specific We bpages including popular pages on Barrett'sesophagus (http://pathology2.jhu.edu/Barrett),on gallbladder and bile duct tumors(http://pathology2.jhu.edu/gbbd), on colorectalmalignancies (http://pathology. j h u . e d u / c o l o n )and on pancreatic cancer( h t t p : / / p a t h o l o g y.jhu.edu/pancreas).

The Division also participates in nationalCME activities, including hosting the AnnualLustgarten Meeting for pancreatic cancerresearch (to be held June 13 & 14, 2001) and,beginning in Fall, the Division will be offering adiagnostic gastrointestinal pathology course.

The Division also participates in medicalstudent education. The Gastrointestinal/Liversection of the Second Year Pathology Courselasts approximately two weeks and it has provenpopular with the students. In the last 5 years,

Faculty Changes

New FacultyFY 2000-2001

Belur S. Bhagavan, M.D. Associate Professor GI/Liver PathologyE. Rene Rodriguez, M.D. Associate Professor Cardiopulmonary Path Rubin M. Tu d e r, M.D. Associate Professor Cardiopulmonary PathPatricia M. Alli, M.D. I n s t r u c t o r C y t o p a t h o l o g yAnbazhagan Ramaswamy, M.D., Ph.D. I n s t r u c t o r Molecular PathologyIe Ming Shih, M.D., Ph.D. I n s t r u c t o r Gyn PathologyGloria H. Su, Ph.D. I n s t r u c t o r GI/Liver PathologyEdward G. We i r, M.D. I n s t r u c t o r H e m a t o l o g y

FY 2001-2002Charles G. Eberhart, M.D. I n s t r u c t o r N e u r o p a t h o l o g yRobb E. Wilentz, M.D. I n s t r u c t o r GI/Liver Pathology

D e p a r t u r e sFred Sanfilippo, M.D., Ph.D Baxley Professor S r. Vice President for

& Director Health Sciences andDean, College ofMedicine & Public HealthOhio State University

James H. Nichols, Ph.D. Assistant Professor Medical DirectorClinical ChemistryBaystate Medical CenterSpringfield, MA

P r o m o t i o n sEdward F. McCarthy, Jr., M.D. P r o f e s s o r Bone PathologySusan H. Eshleman, M.D., Ph.D. Associate Professor Transfusion MedicineLaura A. Guay, M.D. Associate Professor M i c r o b i o l o g yWalter E. Kaufmann, M.D. Associate Professor N e u r o p a t h o l o g yBrigitte M. Ronnett, M.D. Associate Professor Gyn PathologyScheherazade Sadegh-Nassseri, Ph.D. Associate Professor I m m u n o l o g yPhilip C. Y. Wong, Ph.D. Associate Professor N e u r o p a t h o l o g ySusan C. Abraham, M.D. Assistant Professor GI/Liver PathologyKarin D. Berg, M.D. Assistant Professor Molecular PathologyZhiping Qian, M.D. I n s t r u c t o r I m m u n o l o g y

Sharon Swierczynski, M.D., Ph.D.

Sharon is a survivor of the Johns

Hopkins School ofMedicine and the sec-ond year Pathologycourse. Prior to comingto Hopkins, she earnedher Ph.D. in

Biochemistry at Duke and an undergraduatedegree in Chemistry at Juniata College inPennsylvania. Sharon has investigated glycogenmetabolism and voltage-dependent sodiumchannels. In her spare time, she likes to playthe piano, hike and enjoys baking.

Continued from page 3

Division in Highlight:Gastrointestinal/Liver

Pathology

members of the GI/Liver Division have receivedfour teaching awards from the Medical Schoolincluding the Professor's Award, the W. BarryWood Award, and the Excellence in Te a c h i n gAward (twice).

There is much more going on in theDivision, but we hope we have given you a senseof the breadth and depth of the research, patientcare and educational activities in the Division. n Michael Goggins

Page 6

The family and friends of Michael Rolfe haveturned their terrible loss into something

wonderful. With vision, dedication, and hardwork, the Michael Rolfe Research Foundationhas raised over $290,000 for pancreatic cancerresearch at Johns Hopkins. The generous sup-port of the Foundation has led to the creation ofa new laboratory for pancreatic cancer researchin the Department of Pathology. This laboratorywill be headed by Dr. Gloria Su and will be dedi-cated to developing a much-needed mousemodel of pancreatic cancer. At the same time,the Michael Rolfe Research Foundation hashad the vision to establish an endowment. Theinterest income from this endowment will beused to support a laboratory in this Departmentdedicated to developing an early detection testfor pancreatic cancer. Just as there is a PSA testfor prostate cancer, so too is this laboratory

d e d icated to developing a test forthe early detection of pancreaticc a n c e r.

On November 30, 2000, JudyRolfe, Lisa Rolfe Burik, JamesRolfe, and Hazel Herzog visitedour Department and presentedthe pancreatic cancer researcherswith a check for $100,000. Thischeck represents the incomefrom the 1st Annual MichaelRolfe Research Foundation Galathat was held in Highland Park,Illinois in August. A photographof their visit to Hopkins which included the dedi-cation of a plaque in honor of Michael Rolfe isshown above. Details about Michael Rolfe andthe Michael Rolfe Research Foundation can befound elsewhere on this Web s i t e

Private Giving Makes a Difference

Hazel Herzog, Mike Goggins, Gloria Su, Ralph Hruban, Judy Rolfe,Lisa Rolfe Burik, Jim Rolfe

(http://pathology2.jhu.edu/pancreas/mrolfe.htm). The generous support of the Michael Rolfe

Research Foundation exemplifies how privatedonations can honor loved ones and, at thesame time, have a significant impact on theDepartment's research efforts. n

Ancient MicroworldsThe Book Goes on TourGiraud Foster & Norm Barker

With a collaborative effort of over ten yearsGiraud Foster and Norman Barker have

just published a book entitled AncientMicroworlds. When viewing fossils under highmagnification their intricate beauty is revealed.

What soon becomes apparent is the mineralcomponents of some specimens are exceedinglycolorful, and when light is diffracted by internalstructures, other worldly images are formed. Inthe tragic beauty of life forms long extinct thereis also a foreboding reminder of life’s precari-ousness and our own fragility. With high mag-nification and light refraction, recurring pat-terns and saturated mineral pigments areabstracted. Secret worlds are revealed, with

misty pools, gem encrustationsand fractured rainbows. In aphoto essay of beautiful fossilsfrom around the world, theyhave produced a true union ofArt and Science that is areminder that extinction is partof life.

Printed in Italy and pub-lished by Custom & LimitedEditions (ISBN: 1-881529-65-7), Ancient Microworlds con-tains photographs of stunningfossils from all over the world.The book is available fromJohns Hopkins Medical Book-store. Along with the new

book, there is a traveling exhibit of sixty-sixphotographs that will be on display at NaturalH i s t o r y, Science Museums and Galleries aroundthe country. In May the Exhibit will be at TheAmerican Museum of Natural History in NewYork. Over the next four years the work will beexhibited in fifteen different cities. Come andenjoy a small show of the work on the first floorof Pathology in the Hall Gallery.The Artists

Giraud Foster is a retired physician, bio-chemist and archeologist who has used photog-raphy in all his professions. He has pioneeredimage production using radiant energy.. He hasalso had several one-man exhibits and is cur-rently working on a book that includes thesights and sounds of New Guinea.

Norm Barker is a graduate of TheMaryland Institute of Art and The JohnsHopkins University. He is an Assistant Professorof Pathology and Art as Applied to Medicine atThe Johns Hopkins University Medical School.His scientific images have won many awardsand his photographs appear in journals andtextbooks worldwide. n

Ammonite x5 Devonian, MoroccoThis cross section of an ammonite has been polished to show the inter -nal chambers and the minerals deposited within.

Page 7

New Grants and Contracts Awarded to Pathology Faculty

FA C U LTY MEMBER AWARD TYPE A G E N C Y D AT E S T O TAL FUNDINGBerg, Karen C o n t r a c t GeneLogic, Inc. 0 9 / 0 1 / 0 0 - 0 8 / 3 1 / 0 3 1,029,788 Borchelt, David G r a n t Hereditary Disease Fdtn. 0 8 / 0 1 / 0 0 - 0 7 / 3 1 / 0 1 56,000 Borchelt, David G r a n t Huntington's Disease Soc. 1 0 / 0 1 / 0 0 - 0 9 / 3 0 / 0 1 89,410 Borowitz, Michael F e l l o w s h i p Sysmex, Inc. 0 7 / 0 1 / 0 0 - 0 6 / 3 0 / 0 1 50,000 B u r g e r, Peter G r a n t Children's Cancer Fdtn. 1 0 / 0 1 / 0 0 - 0 9 / 3 0 / 0 1 61,957 Cai, Huaibin G r a n t Adler Foundation 0 7 / 0 1 / 0 0 - 0 6 / 3 0 / 0 1 35,000 Caturegli, Patrizio R01 Grant N I H / N I D D K 0 3 / 0 1 / 0 0 - 0 2 / 2 8 / 0 4 904,215 Chan, Daniel C o n t r a c t C i p h e r g e n 1 2 / 0 1 / 0 0 - 1 1 / 3 0 / 0 5 4,308,862 Demarzo, Angelo SPORE supplement N I H / N C I 0 6 / 0 1 / 0 0 - 0 5 / 3 1 / 0 1 529,222 Demarzo, Angelo G r a n t C a p C u r e 0 1 / 0 1 / 0 1 / 1 2 / 3 1 / 0 1 100,000 Demarzo, Angelo G r a n t Charlotte Geyer Fdtn. 1 2 / 0 1 / 0 0 / 1 1 / 3 0 / 0 1 50,000 D e p a r t m e n t F e l l o w s h i p Q u e s t 0 7 / 0 1 / 0 0 - 0 6 / 3 0 / 0 1 50,000 D u m l e r, Steve R01 Grant N I H / N I A I D 0 9 / 0 1 / 0 0 - 0 8 / 3 1 / 0 4 945,221 Eberhart, Charles G r a n t Childhood Brain Tumor Fdtn. 0 7 / 0 1 / 0 0 - 0 6 / 3 0 / 0 1 23,602 Eberhart, Charles G r a n t The Brain Tumor Society 1 0 / 0 1 / 0 0 - 0 9 / 3 0 / 0 1 48,744 Eberhart, Charles G r a n t Howard Hughes Medical Inst. 0 9 / 0 1 / 0 0 - 0 8 / 3 1 / 0 3 270,000 Goggins, Michael G r a n t Natl. Pancreas Fdtn. 0 7 / 0 1 / 0 0 - 0 6 / 3 0 / 0 1 59,392 Griffin, Constance U24 Grant N I H / N C I 0 8 / 0 1 / 0 0 - 0 7 / 3 1 / 0 3 2,564,827 G u a y, Laura U01 Grant N I H / N I A I D 0 7 / 0 1 / 0 0 - 0 6 / 3 0 / 0 5 10,487,603 Haas, Mark Inst. Grant J H U / C T C 0 7 / 0 1 / 0 0 - 0 6 / 3 0 / 0 1 4,800 Jackson, Brooks U01 Grant N I H / N I A I D 0 3 / 0 1 / 0 0 - 0 2 / 2 8 / 0 5 9,589,335 Jackson, Brooks G r a n t Pediatric AIDS Foundation 0 3 / 0 1 / 0 0 - 0 2 / 2 8 / 0 1 100,000 Jackson, Brooks U01 Grant N I H / N I A I D 0 7 / 0 1 / 0 0 - 0 6 / 3 0 / 0 5 4,090,100 Jackson, Brooks G r a n t World AIDS Foundation 0 9 / 0 1 / 0 0 - 0 8 / 3 1 / 0 1 100,000 Jackson, Brooks C o n t r a c t Gen-Probe, Inc. 0 6 / 0 5 / 0 0 - 0 1 / 3 1 / 0 1 175,083 Jackson, Brooks C o n t r a c t N I H / N I A I D 0 1 / 0 1 / 0 0 - 1 2 / 3 1 / 0 4 1 , 4 0 2 , 9 5 4Koliatsos, Va s s i l i s R01 Grant N I H / N I A 0 4 / 0 1 / 0 0 - 0 3 / 3 1 / 0 5 1,729,387 Koliatsos, Va s s i l i s Inst. Grant JH Center for ALS Research 0 8 / 0 1 / 0 0 - 0 7 / 3 1 / 0 1 104,300 Kuhajda, Frank C o n t r a c t FasGen, Inc. 1 2 / 0 1 / 0 0 - 1 1 / 3 0 / 0 2 1,600,000 Kuhajda, Frank R01 Grant N I H / N C I 0 7 / 0 1 / 0 0 - 0 6 / 3 0 / 0 4 1,178,100 Lyons, Ernest Inst. Grant JH Center for ALS Research 0 8 / 0 1 / 0 0 - 0 7 / 3 1 / 0 1 75,000 Martin, Lee R01 Grant N I H / N I A 0 3 / 0 1 / 0 0 - 0 2 / 2 8 / 0 4 1,014,596 Ness, Paul C o n t r a c t American Red Cross 0 4 / 0 1 / 0 0 - 0 3 / 3 1 / 0 1 66,999 Perlman, Elizabeth G r a n t A m e r. Cancer Society 0 1 / 0 1 / 0 1 - 1 2 / 3 1 / 0 2 250,000 Perlman, Elizabeth G r a n t Children's Cancer Fdtn. 1 0 / 0 1 / 0 0 - 0 9 / 3 0 / 0 1 79,513 R a m a s w a m y, Anbazhagan G r a n t US Army 0 9 / 0 1 / 0 0 - 8 / 3 1 / 0 1 81,950 Roden, Richard G r a n t Cancer Reseach Inst. 0 7 / 0 1 / 0 0 - 0 6 / 3 0 / 0 3 295,188 Roden, Richard G r a n t Cancer Reseach Fdtn. 0 7 / 1 5 / 0 0 - 0 7 / 1 4 / 0 2 60,000 Sadegh-Nasseri, S. G r a n t US Army 0 8 / 1 4 / 0 0 - 8 / 1 3 / 0 3 732,547 Shih, Ie-Ming G r a n t A m e r. Cancer Society 0 7 / 0 1 / 0 0 - 0 6 / 3 0 / 0 1 20,000 Su, Gloria Inst. Grant J H U / I R G P 1 2 / 0 1 / 0 0 - 1 1 / 3 0 / 0 1 19,998 Su, Gloria G r a n t A m e r. Cancer Society 0 7 / 0 1 / 0 0 - 0 6 / 3 0 / 0 1 20,000 Wasowska, Barbara R01 Grant N I H / N H L B I 0 7 / 0 1 / 0 0 - 0 6 / 3 0 / 0 4 1,309,000 Wong, Phil R01 Grant N I H / N I N D S 0 4 / 0 1 / 0 0 - 0 3 / 3 1 / 0 5 1,431,720 Wong, Phil Inst. Grant JH Center for ALS Research 0 8 / 0 1 / 0 0 - 0 7 / 3 1 / 0 1 81,000 Wu, T. C . P01 Grant N I H / N I A I D 0 7 / 0 1 / 0 0 - 0 6 / 3 0 / 0 4 2,901,867

FUNDING OUR FUTURE

D espite the wonderful impact theDepartment of Pathology has had over the

last century, we have a woefully inadequateendowment. Over the past two years, with yourhelp, we have taken several large steps to correctthis inadequacy. We have done this with twogoals in mind. First, we wanted to honorextraordinary faculty members who have notonly touched our lives but who have also had asignificant impact on their fields. Second, wehave tried to focus on helping our talentedyoung trainees - the future of pathology. Overthe past two years we have launched four cam-paigns. We want to inform you of these excit-ing efforts, to thank all of you who have con-tributed and to encourage those of you whohaven't yet contributed to please consider mak-ing a pledge.

The Joseph C. Eggleston Fund in Surgical Pathology

The Joseph C. Eggleston Fund in SurgicalPathology was only recently launched(December 2000) with an anchor gift fromSylvia Eggleston-We h r. This fund honorsJoseph C. Eggleston, M.D. '62, former Director

of SurgicalPathology andProfessor ofP a t h o l o g y. Dr.Eggleston was ano u t s t a n d i n gteacher whoseinfluence was feltat every level of themedical commu-nity - students,

housestaff in pathology, physicians in trainingin other departments, faculty and colleagues.He was a life-long student of human diseaseand a wonderfully talented diagnostic patholo-gist. It is only fitting that we honor him by cre-ating the Joseph C. Eggleston Fund in SurgicalP a t h o l o g y. The income from this endowedfund will be allocated each year to SurgicalPathology residents or junior faculty membersin the division of Surgical Pathology for projectsthat support their career development inSurgical Pathology. These may include

research projects or other activities that supporttheir training and careers. The fund remainsopen for additional gifts with the hope that itwill reach a level sufficient to fund a facultydevelopment chair or professorship in surgicalp a t h o l o g y.

The Yener S. Erozan Fellowship inC y t o p a t h o l o g y

The campaign to endow the Yener S.Erozan Fellowship in Cytopathology waslaunched in May 2000. This fellowship honorsYener Erozan, M.D. Director Emeritus of theCytopathology Institute and past president ofthe American Society of Cytopathology. The fel-lowship will emphasize diagnostic, teaching,and clinical research activities that are so muchof Dr. Erozan's life. The income from thisendowed fund will be allocated to a fellow inCytopathology for projects that support theircareer development.

The Robert H. Heptinstall FellowshipThe campaign to endow the Robert H.

Heptinstall Fellowship was launched inFebruary 1999 with an anchor gift from theMirowski Family Foundation, Inc. This fellow-ship honors Robert H. Heptinstall, M.D., formerBaxley Professor and Director of Pathology andauthor of the classic textbook, "Heptinstall'sPathology of the Kidney." As Baxley Professorand Director, Heppy led the Department fromthe microscope age into the modern molecularage, and, importantly, he served as a mentor toover 200 residents and fellows. The Robert H.Heptinstall Fellowship is designed to promotethe research activities or clinical training of out-standing young pathologists pursuing careersin research.

The John H. Yardley Fellowship inGastrointestinal Pathology

The campaign to endow the John H.Yardley Fellowship in GastrointestinalPathology was launched in April 1999 and hon-ors John H. Ya r d l e y, M.D. former BaxleyProfessor and Director of Pathology. Dr.Yardley's legacy is perhaps best expressed in histeaching of fellows. Over the years, he hasinstilled in his fellows a lifetime love ofresearch, patient care, and teaching. The JohnH. Yardley Fellowship was designed to promotethe research activities and/or clinical training ofpromising pathologists pursuing advancedtraining in the field of gastrointestinal diseasein the Department. Even more importantly, hisfellowship program fosters intellectual curiosity,creating leaders who have pushed the specialtyof gastrointestinal pathology to new heights.This fellowship is now almost fully endowedand we are pleased to announce that the firstrecipient of this fellowship is a talented youngpathologist with a strong interest in liver dis-ease, Dr. Michael Torbenson.

All of these campaigns remain open,but with your help they will be fully endowed.Please contact Jennifer Galford at 410-955-2163or jgalfor@jhmi.edu for additional informationor you may send your tax-deductible contribu-tion payable to The Johns Hopkins University.

Mail to:attn: Mabel P. Smith

Department of PathologyJohns Hopkins Hospital

Carnegie 428600 N. Wolfe Street

Baltimore, MD 21287-6417Thanks to all of you that have made this

support a reality for our young pathologists. nJoseph C. Eggleston

Page 8

Page 9

FACULTY ACTIVITIES

Laura Barisoni, M.D., who trained atColumbia, has joined the Department as ajunior faculty member, working on therenal biopsy service, and pursuingresearch interests at the NIH.

Jonathan Epstein, M.D., gave the Norman K.Probstein Radiation Oncology Lecture atthe Washington University School ofMedicine in St. Louis, Missouri, inNovember 2000.

Mark Haas, M.D., Ph,D., was an invited facul-ty participant at the 2000 National KidneyFoundation Clinical Meetings in Atlanta,where he chaired an interactive session onrenal biopsy pathology and presented atalk at a symposium entitled "What's newin glomerulonephritis". He will serve asco-chair of the Renal Pathology Societysymposium on amyloidosis at the 2001American Society of Nephrology meetingin San Francisco. His paper, "Etiologiesand outcome of acute renal insufficiencyin older adults: a renal study biopsy of 259cases," published in the March 2000American Journal of Kidney Diseases, wasthe subject of a highly favorable editorialin that journal.

Ralph Hruban, M.D., has been selected by theExecutive Committee of the United Statesand Canadian Academy of Pathology asthe recipient of the 2001 Young In-vestigator Award. This singular honorconsists of a plaque and a monetaryaward. Dr. Hruban, who is Director of theDivision of Gastrointestinal/Liver Path-o l o g y, has focused his investigative effortson pancreatic neoplasia. Dr. Hruban hasused molecular discoveries to develop newtools to aid in the diagnosis of pancreaticc a n c e r. For his research work in the path-ology of pancreatic cancer, for his excel-lence as a teacher, for his participation inthe development of a progression model ofpancreatic neoplasia and for his outstand-ing contributions to pancreatic cancera d v o c a c y, Dr. Hruban is presented with theYoung Investigator Aw a r d .

Brooks Jackson, M.D., gave the ReynoldsHistorical Lecture at the University ofAlabama School of Medicine in Birm-ingham, Alabama, on February 9, 2001.D r. Jackson is one of three honorees fromJohns Hopkins to have been asked to givethis lecture in the past 22 years. The other

two past honorees are Dr. Victor McKusickand Dr. Donald Henderson.

Lorraine Racusen, M.D., is co-organizing theSixth Banff symposium on The Pathologyof Solid Organ Transplantation, to be heldin Banff, Canada, in April 2001. She willalso be giving invited presentations at theUSCAP meetings in March, at theAmerican Society of Transplant Physiciansannual meeting in May, and the ASTPFellows Symposium in July. At the USCAPmeeting, she will join Dr. Surya Seshanfrom Cornell Medical Center in presentinga short course on glomerular diseases.

Noel Rose, M.D., Ph.D., was elected anHonorary Member of the American Societyfor Microbiology which is "the highestrecognition within the power of theCouncil and Members." Dr. Rose was alsoelected Chairman of the American Boardof Medical Laboratory Immunology.

Dorothy Rosenthal, M.D., has been electedpresident of the American Society ofCytopathology for 2000-2001. n

Raymond (Pete) Lund, Associate Professor of Pathology, will be Retiring June 30, 2001

As Director of the Pathology PhotographyLaboratory for the past thirty-three years,

M r. Lund built a self-sustaining photographyand graphic arts operation that is recognizednationally and internationally for its excellencein service, technology, and training.

Pathology Photography and Graphic Arts isa full service operation in the biomedical field.Every process has been automated and or com-puterized to provide high quality service andcost effectiveness. This laboratory has been inthe forefront of assessment and application ofnew methods in medical photography andgraphic arts. A network has been establishedthat allows user access to slide production serv-ices via telephone and the internet.Photomicrography has been digitized for prepa-ration of journal illustrations, posters, andgrant applications. Equipment has been

installed that allows users to make posters ontheir own computer and transmit them to thelaboratory where 4’ x 8’ posters are made inone day.

M r. Lund is the sole author on ten pub-lished, peer-reviewed papers on the subject oflaboratory development and professional educa-tion in the field of biomedical photography. Hiscomputer related papers are the first in the fieldon computer development of a biomedical pho-tography laboratory. The papers were publishedin Great Britain, Norway, Sweden, Denmark andG e r m a n y. These papers have stimulated inter-est in the department. Many guests from allover the world have come to see this lab inoperation. Such visitors have come from Japan,German, Norway, Sweden, Denmark, Austria, Raymond Lund

Continued on page 10

Page 1 0

Jordan, Nigeria, South Africa, Italy, Scotland,England, Ireland Canada, Australia, and otheruniversities in the United States.

M r. Lund has made presentations and con-ducted workshops on some aspect of Pathologyand Graphic Arts at all of the major BiomedicalPhotography meetings in the United States andEurope.

Training has been a major aspect of thisoperation since it opened in 1962. A two-yearon-the-job training program in biomedicalphotography has been the mainstay of staffingfor the operation. Approximately 150 studentshave completed the two-year program.Students are selected from colleges and univer-sities around the country. Graduates of thisprogram are employed at Sinai Hospital,University of Maryland, Johns Hopkins BayviewMedical Center, Franklin Square Hospital,Union Memorial Hospital, Glaxo DrugC o m p a n y, Kodak, Rochester Institute ofTechnology School of Medical Photography,Boeing Aircraft, California Medical ConferenceC o m p a n y, Maryland-State Police Crime Lab, theFederal Bureau of Investigation, and the

Smithsonian Institute. M r. Lund’s teaching also extends to master’s

degree students in the Department of Art asApplied to Medicine.

M r. Lund has served on the Advisory Boardof the Photography Department at DundalkCommunity College for fifteen years. Hereceived the Louis Schmidt Award, the highestaward given by the U. S. BiologicalPhotographers Association for outstanding con-tributions to the field of biomedical photogra-p h y. He was awarded the World Certificate ofMerit for organizing the first World Congress inBiomedical Photography. This was the firstworld-wide meeting on biomedical communi-cation.

In 1994, he received an HonoraryFellowship from the Institute of MedicalIllustration, United Kingdom. Only one otherperson has received the award from the UnitedS t a t e s .

M r. Lund has been a member of theBiological Photographic Association (BPA) for30 years. He has served as chairman of mostcommittees in the BPA, the Health SciencesCommunication Association, the Association of

Continued from page 9

Lund will be Retiring June 30, 2001Biomedical Communication Directors, and theWorld Congress in Biomedical Photography. Hewas President of the Biological PhotographicAssociation from 1993-1995.

A Board of Registry for biological photogra-phers was established in 1963. Mr. Lundbecame registered in 1969 and he becameChairman of the Registry in 1973. He workedto make the registry a program that would gen-erate qualified medical photographers. A com-plete oral review program and written examwas established so that it could be taken at anycollege or university testing center. There arecurrently five registered medical photographerson his staff.

In summary, Pete has made great contribu-tions to our department, to the MedicalInstitutions and to the field of biomedical pho-t o g r a p h y. His leadership and photographyoperation is considered one of the majorstrengths of the Department of Pathology andthe Medical Institutions.

We wish to thank Pete for his outstandingcontributions to the Department of Pathologyand to the field of biomedical photography.Pete, we wish you a long, healthy retirement. n

March 5 Johns Hopkins Pathology Alumni ReceptionAtlanta Marriott Marquis, Consulate Room5:30 p.m. – 7:30 p.m.Atlanta, Georgia

April 15-21 National Medical Laboratory We e kApril 26-28 Mastering the Challenges of Cytopathology

Admiral Fell Inn, BaltimoreMay 16 Pathology Young Investigators’ Day

Turner Auditorium, Johns Hopkins University School of Medicine, Baltimore

May 16-17 Critical Issues in Laboratory Medicine CourseMarriott Waterfront Hotel, Baltimore

May 18-19 Critical Issues in Surgical Pathology CourseMarriott Waterfront Hotel, Baltimore

June 1 Pathology Awards DinnerHotel Belvedere, Baltimore

June 7-9 Johns Hopkins Medical and Surgical AssociationBiennial MeetingTurner Auditorium, Johns Hopkins UniversitySchool of Medicine, Baltimore

June 8 Biennial Pathology Grand Rounds Mountcastle Auditorium, Preclinical Teaching Building, Johns Hopkins University School of Medicine, Baltimore

June 14 3rd Annual Lustgarten Meeting for Pancreas CancerResearch-Pancreatic Cancer: From Genes to Tr e a t m e n tWood Basic Science Building, Johns Hopkins University School of Medicine, Baltimore

Nov 2-3 4th Annual Gynecologic Pathology: Approaches to Common Problems with Emphasis on New Entities and Te c h n i q u e sRenaissance Harborplace Hotel, Baltimore

Calendar

Page 1 1

The year 2000 was quite excit-ing for the Division of

Cytopathology! Just recently,under the direction of Dr. DouglasP. Clark, the all-newCytopathology Website is up andrunning. The site offers stream-lined information in the field ofC y t o p a t h o l o g y, highlighting theDivision and its role in today’smarket. Users may log on to thesite to gain information on themost recent advancements inCytopathology at Johns Hopkinsas well as information on the fac-ulty and upcoming events. Thesite also advertises the many different servicesand courses the Division offers as well as con-tact information for details. In the future, aspecific section of the site will offer CME creditsto users interested in viewing material from theweekly Interesting Case and RadiologyPathology Correlation Conferences. Anyoneinterested in checking out the site should visithttp://162.129.103.53/cytopath, and be sure tocheck back periodically for updates.

Drs. Syed Ali and David Steinberg havebeen working diligently to finish a projectinvolving the Second Year Medical Students.To g e t h e r, they have developed a state of the artteaching mechanism involving electronic mod-ules to display images and text in the classroomsetting with an LCD projector. Each of theclassrooms will be equipped with the appropri-

ate materials, predicting the wayteaching will be done in thefuture. David Steinberg, M.D.was the recipient of the Wa r r e nR. Lang Award for Best Paper bya Resident/Fellow at theAmerican Society ofCytopathology National ASCMeeting in Philadelphia this pastNovember for his efforts in thep r o j e c t .

With the participation of allthe faculty and fellows, Dr. Ye n e rErozan is preparing a compre-hensive CD-ROM onC y t o p a t h o l o g y. A contract has

been signed with the ASCP Press, who will beproducing and marketing the project. Drs.David Steinberg, Beth Allen, and Joe Kronz havebeen working closely with Dr. Erozan (editor) inthe selection of representative slides over the lastfew years. Thus far, over 1200 images havebeen compiled through the organizational andcomputer efforts of the group. The final prod-uct is expected to exceed 3000 images.

This Spring,D r. Dorothy L.Rosenthal willhost the seconda n n u a l“Mastering theChallenges inC y t o p a t h o l o g y ”f e a t u r i n gRichard DeMay,M.D. The courseis available topathologists interested in clinical cytopathology.Participants are involved in a two-part programcovering topics such as difficult diagnostic areasof cytopathology, new techniques to process anddefine challenging samples, and several otherkey areas of clinical cytopathology. This year’sJohn K. Frost Lecturer is Richard DeMay, M.D.,author of the popular textbook, The Art &Science of Cytopathology. Dr. DeMay is aProfessor of Clinical Pathology at the Universityof Chicago. The dates of this year’s course areApril 26-28. For more information, contact

On the Web…

The department has made a concerted effortto increase its presence on the Web. Our

professional education Web sites provide educa-tional material including great cases, and aretargeted to physicians and allied health carepersonnel. Our disease-specific Web sites are tar-geted to patients and their families but alsoincluded some professional-level material.

In order to support this growth we havehired a number of staff members dedicated todeveloping these sites. Our team now consists of5 core individuals…Coreen Byam, Web Production Coor d i n a t o rDarlene Follin, C o n s u l t a n tBeth Hornsby, Laboratory SpecialistAmanda Lietman, Information Resources

C o o rd i n a t o rJennifer Parsons, Web Development

C o o r dinator/Medical IllustratorLater this year, look for a better- d e s i g n e d

and easy-to-use Pathology Homepage( h t t p : / / p a t h o l o g y.jhu.edu), audio and video ofselected conferences hosted on campus, newanimations and more great cases.

Department members interested in develop-ing new departmental web sites are invited toattend the Web Development Group open meet-ings held every Monday at 10:00 (Carnegie489A). Please contact Coreen Byam at 410-614-3589 if you are interested in attending a meeting.

Great Things Are Happening in CytopathologyShirley Long by email at salong@jhmi.edu.

D r. Rosenthal is also the president of theASC this year. One of the major initiatives ofthe Society is to promote advocacy for patientsby cytopathology professionals. The impendingshortage of cytotechnologists will also be aprominent focus of the ASC, with the formationof an innovative Educators Forum for theorganization and the profession in general. Forfurther information, and to read Dr. Rosenthal’sP r e s i d e n t ’s Letter, log on to the ASC website atw w w. c y t o p a t h o l o g y. o r g .n

Mastering the Challenges in Cytopathology

Dorothy Rosenthal

Continued on page 12

Department of PathologyJohns Hopkins Medical Institutions600 North Wolfe Street, Carnegie 417Baltimore, MD 21287-6417

(410) 955-9790

J. Brooks Jackson, M.D., M.B.A.Professor and Interim Director

Editorial Staff:Jeannette CastronovaMabel Smith

Technical Advisor:Jerry Arnold

P h o t o g r a p h e r :Jim Durham

Department of Pathology Web Site:w w w. p a t h o l o g y. j h u . e d u

Professional Education Web SitesCase Studies in Clinical Flow Cytometry

h t t p : / / w w w. f l o w c a s e s . o r gNew Site! A free on-line journal. Great Cases and tools for on-linesubmission of interesting cases.

Cytopathology Divisionh t t p : / / p a t h o l o g y. j h u . e d u / c y t o p a t hNew Site! Latest division news, radiology/pathology cases.

Molecular Pathology Diagnostics Laboratoriesh t t p : / / p a t h o l o g y 2 . j h u . e d u / m o l e cIn-depth reference material for assays run in our labs, how torequest consultation services and animations of selected techniques.

Surgical Pathology Unknown Case Conferenceh t t p : / / p a t h o l o g y 2 . j h u . e d u / s pA virtual version of the "unknown" conference. Accredited for 1hour of category 1 CME credit. Updated weekly - A great site to book-m a r k !

Disease-Specific Web SitesBarrett's Esophagus

h t t p : / / p a t h o l o g y 2 . j h u . e d u / b e w e bLots of patient-oriented information plus an illustrated section onGrading Dysplasia in Barrett's Esophagus.

Gallbladder & Bile Duct Cancerh t t p : / / p a t h o l o g y 2 . j h u . e d u / g b b dPatient-oriented material including illustrations, glossary of termsand discussion boar d .

Ovarian Cancerh t t p : / / o v a r i a n c a n c e r. j h m i . e d uNew Site! Developed under the guidance of Sean Patrick, an ovari-an cancer survivor. It contains patient oriented material as well asan overview of the ongoing research in the department.

Pancreatic Cancerh t t p : / / p a t h o l o g y. j h u . e d u / p a n c r e a sA site originally launched in 1995. It contains a very active patientdiscussion board (now boasting over 4,394,354 hits), FrequentlyAsked Questions, as well as information on the new nomenclaturefor classification of duct lesions.

Surgical PathologyUnknown Case

Conference