0
5
10
15
20
25
30
35
Pdi PmusPVI Pmusp Pmusa
0
5
10
15
20
25
30
35
Pdi PmusPVI Pmusp Pmusa
0
5
10
15
20
25
30
35
Pdi PmusPVI Pmusp Pmusa
Pea
k pr
essu
re (
cmH
2O) 0
10
20
30
40
50
60
70
Pdi PmusPVI Pmusp Pmusa
0
10
20
30
40
50
60
70
Pdi PmusPVI Pmusp Pmusa
0
10
20
30
40
50
60
70
Pdi PmusPVI Pmusp Pmusa
Insp
irato
ry d
rive
(cm
H2O
/sec
)
30%
50%
70%
A B
Figure S1
0
2
4
6
8
10
12
14
0 2 4 6 8 10 12 14
0
2
4
6
8
10
12
14
0 2 4 6 8 10 12 14
0
2
4
6
8
10
12
14
0 2 4 6 8 10 12 14
No.1r=0.98S=1.17I=-0.49
r=0.92S=1.59I=-0.14
r=0.93S=1.49I=-0.02
Pdi
Pm
usP
VI
Pmusp
PmusaFigure S21
0
2
4
6
8
10
12
14
0 2 4 6 8 10 12 14
0
2
4
6
8
10
12
0 2 4 6 8 10 12 14
0
2
4
6
8
10
12
0 2 4 6 8 10 12 14
No.2r=0.996S=1.02I=-0.14
r=0.996S=0.96I=-0.29
r=0.995S=0.91I=-0.15
Pdi
Pm
usP
VI
Pmusp
PmusaFigure S22
0
2
4
6
8
10
12
14
0 2 4 6 8 10 12 14
No.3r=0.95S=1.25I=0.46
Pdi
Pm
usP
VI
Figure S23
0
2
4
6
8
10
12
14
0 2 4 6 8 10 12 14
0
2
4
6
8
10
12
14
16
0 2 4 6 8 10 12 14
0
2
4
6
8
10
12
14
16
0 2 4 6 8 10 12 14
Pdi
Pm
usP
VI
No.4r=0.91S=1.20I=1.64
r=0.95S=1.01I=1.20
r=0.92S=1.06I=1.37
Pmusp
Pmusa
Figure S24
0
2
4
6
8
10
12
14
16
18
0 2 4 6 8 10 12 14 16 18
0
2
4
6
8
10
12
14
16
18
0 2 4 6 8 10 12 14 16 18
0
2
4
6
8
10
12
14
16
18
0 2 4 6 8 10 12 14 16 18
No.5r=0.94S=2.03I=1.38
r=0.99S=1.05I=-0.11
r=0.99S=1.06I=-0.20
Pdi
Pm
usP
VI
Pmusp
PmusaFigure S25
0
2
4
6
8
10
12
14
16
0 2 4 6 8 10 12 14 16
0
2
4
6
8
10
12
14
16
18
0 2 4 6 8 10 12 14 16
0
2
4
6
8
10
12
14
16
18
0 2 4 6 8 10 12 14 16
No.6r=0. 83S=1.06I=3.00
r=0.85S=1.04I=2.60
r=0.85S=1.05I=2.65
Pdi
Pm
usP
VI
Pmusp
PmusaFigure S26
0
5
10
15
20
25
30
35
0 5 10 15 20 25 30 35
0
5
10
15
20
25
30
35
0 5 10 15 20 25 30 35
0
5
10
15
20
25
30
35
0 5 10 15 20 25 30 35
No.7r=0. 99S=0.76I=1.41
r=0.99S=0.92I=1.45
r=0.99S=0.91I=1.47
Pdi
Pm
usP
VI
Pmusp
PmusaFigure S27
0
2
4
6
8
0 2 4 6 8
0
2
4
6
8
0 2 4 6 8
0
2
4
6
8
0 2 4 6 8
No.8r=0. 95S=1.66I=0.22
r=0.99S=0.59I=0.59
r=0.98S=0.65I=0.07
Pdi
Pm
usP
VI
Pmusp
PmusaFigure S28
0
2
4
6
8
10
12
14
16
18
0 2 4 6 8 10 12 14 16 18
0
2
4
6
8
10
12
14
16
18
0 2 4 6 8 10 12 14 16 18
0
2
4
6
8
10
12
14
16
18
0 2 4 6 8 10 12 14 16 18
No.9r=0. 94S=1. 74I=0.90
r=0.97S=0.90I=-0.19
r=0.97S=0.88I=-0.13
Pdi
Pm
usP
VI
Pmusp
PmusaFigure S29
0
2
4
6
8
10
12
0 2 4 6 8 10 12
0
2
4
6
8
10
12
0 2 4 6 8 10 12
0
2
4
6
8
10
12
0 2 4 6 8 10 12
No.10r=0. 83S=1. 27I=0.48
r=0.80S=0.72I=0.31
r=0. 83S=0.80I=0.17
Pdi
Pm
usP
VI
Pmusp
PmusaFigure S210
0
2
4
6
8
10
12
14
16
18
0 2 4 6 8 10 12 14 16 18
0
2
4
6
8
10
12
14
16
18
0 2 4 6 8 10 12 14 16 18
0
2
4
6
8
10
12
14
16
18
0 2 4 6 8 10 12 14 16 18
No.11r=0. 98S=1. 01I=0. 21
r=0. 97S=0. 89I=0.22
r=0. 98S=0. 99I=0.007
Pdi
Pm
usP
VI
Pmusp
PmusaFigure S211
0
0,5
1
1,5
2
2,5
3
3,5
4
4,5
5
0 20 40 60 80 100
Pdi
PmusPVI
Pmusp
Pmusa
% of inspiratory time
cmH
2O
0
0,5
1
1,5
2
2,5
3
3,5
4
4,5
5
0 20 40 60 80 100
A B
cmH
2O
Figure S3
0
5
10
15
20
25
30
35
0 5 10 15 20 25 30 35
-8
-6
-4
-2
0
2
4
6
8
10
12
0 5 10 15 20 25 30 35
0
5
10
15
20
25
30
35
0 5 10 15 20 25 30 35
-8
-6
-4
-2
0
2
4
6
8
10
12
0 5 10 15 20 25 30 35
0
5
10
15
20
25
30
35
0 5 10 15 20 25 30 35
-8
-6
-4
-2
0
2
4
6
8
10
12
0 5 10 15 20 25 30 35
r=0.84, y=5.6+0.6x
r=0.83, y=1.4+0.8x
r=0. 84, y=1.6+0.8x
Pe
akP
mu
s PV
I
--Pe
akP
di
Pe
akP
mu
s PV
I
--Pe
akm
us p
Pe
akP
mu
s PV
I
--Pe
akP
mu
s a
(PeakPmusPVI+PeakPdi)/2
(PeakPmusPVI+PeakPmusp)/2
(PeakPmusPVI+PeakPmusa)/2
Pe
akP
mu
s PV
IP
ea
kPm
us P
VI
Pe
akP
mu
s PV
I
PeakPdi
PeakPmusp
PeakPmusa
Figure S4
0
10
20
30
40
50
60
70
0 10 20 30 40 50 60 70
-12
-8
-4
0
4
8
12
16
0 10 20 30 40 50 60 70
0
10
20
30
40
50
60
70
0 10 20 30 40 50 60 70
-12
-8
-4
0
4
8
12
16
0 10 20 30 40 50 60 70
0
10
20
30
40
50
60
70
0 10 20 30 40 50 60 70
-12
-8
-4
0
4
8
12
16
0 10 20 30 40 50 60 70
r=0.88, y=7.2+0.8x
r=0.95, y=-2.4+1.1x
r=0. 94, y=-1.0+1.0x
dp
/dt
Pm
us P
VI
dp
/dt
Pm
us P
VI
dp
/dt
Pm
us P
VI
dp/dt Pdi
dp/dt Pmusp
dp/dt Pmusa
dp
/dt
Pm
usP
VI
-dp
/dt
Pd
i d
p/d
t P
mu
sPV
I-d
p/d
t P
mu
sp
dp
/dt
Pm
usP
VI
-dp
/dt
Pm
usa
(dp/dt PmusPVI+dp/dt Pdi)/2
(dp/dt PmusPVI+dp/dt Pmusp)/2
(dp/dt PmusPVI+dp/dt Pmusa)/2
Figure S5
0
2
4
6
8
10
12
0 2 4 6 8 10 12
PTPPdiP
TP
Pm
us P
VI
-4
-2
0
2
4
0 2 4 6 8 10 12
0
2
4
6
8
10
12
0 2 4 6 8 10 12
PTPPmusp
-4
-2
0
2
4
0 2 4 6 8 10 12
0
2
4
6
8
10
12
0 2 4 6 8 10 12
-4
-2
0
2
4
0 2 4 6 8 10 12
r=0.80, y=0.6x+2.2
r=0.77, y=1.4+0.6x
r=0. 78, y=1.3+0.6x
PT
PP
mu
s PV
I
--PT
PP
di
PTPPmusa
PT
PP
mu
s PV
I
--PT
PP
mu
s p
PT
PP
mu
s PV
I
--PT
PP
mu
s a
(PTPPmusPVI+PTPPdi)/2
(PTPPmusPVI+PTPPmusp)/2
(PTPPmusPVI+PTPPmusa)/2
PT
PP
mu
s PV
IP
TP
Pm
us P
VI
Figure S6
10
15
20
25
30
35
40
10 15 20 25 30 35 40
Ersp
Ers
PV
I
-10
-5
0
5
10
15
10 15 20 25 30 35 40
r=0.91 y=-2.2+1.2x 10
15
20
25
30
35
10 15 20 25 30 35
ErsPAV+
Ers
PV
I
-10
-5
0
5
10
15
10 15 20 25 30 35
r=0.74 y=7.1+0.6x
(ErsPVI+Ersp)/2
(ErsPVI+ErsPAV+)/2
Ers
p-E
rsP
VI
Ers
PA
V+-E
rsP
VI
Figure S7
0
5
10
15
20
0 5 10 15 20
RrsPAV+R
rsP
VI
-14-12
-10-8-6-4
-2024
68
0 5 10 15 20
0
5
10
15
20
0 5 10 15 20
Rrsiso
-14-12
-10-8-6-4
-2024
68
0 5 10 15 20
0
5
10
15
20
0 5 10 15 20
-14-12
-10-8-6
-4-2
024
68
0 5 10 15 20
0
5
10
15
20
0 5 10 15 20
-14-12
-10-8-6
-4-2
024
68
0 5 10 15 20
Rrsmin
Rrsmax
Rrs
PV
IR
rsP
VI
Rrs
PV
I
r=0.69, y=1.4+1.2x
r=0.89, y=1.3+0.8x
r=0. 64, y=5.1+1.0x
r=0. 79, y=0.7+0.8x
(RrsPVI+RrsPAV+)/2
(RrsPVI+Rrsiso)/2
(RrsPVI+Rrsmin)/2
(RrsPVI+Rrsmax)/2
Rrs
PA
V+
--Rrs
PV
IR
rsis
o--R
rsP
VI
Rrs
min
--Rrs
PV
IR
rsm
ax--R
rsP
VI
Figure S8
