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Pfi zer, lnc. - 2009 Vijaya Narapareddy University of Denver On May 9,2009, Japanese pharmaceutical manufacturer Eisai threatened Pfizer to termi- nate its long-standing partnership on the news of Pflzer's proposed acquisition of Wyeth. Eisai's venture with Pflzer dates back to the mid-1990s when Pfizer entered into an alliance to sell Eisai's Aricept, the world's leading medicine fur the treatment of Alzheimer's disease. Headquartered in New York City, Pfizer generated about $482 mil- lion in 2008 from the sale of Aricept, an increase of 20 percent fiom 2007, as shown in Exhibit l. Pflzer vows to fight back, claiming that Eisai lacks any legal basis for termina- tion of their alliance. Pfizer engages in the discovery, development, manufacture, and marketing of prescrip- tion medicines for humans and animals worldwide. Some of its well-known drugs are Lipitor, Viagra, Lyrica, Zeldox, and Aricept used for people, as well as Draxxin used fbr cattle. The proposed Ptizer acquisition of Wyeth, a company based in Madison, New Jersey, for a cash and stock purchase of $68 billion would enable Pflzer to diversity its product offer- ings and make further inroads into emerging markets. Exhibit 2 provides details of the ben- efits of the proposed Wyeth acquisition. Pfizer operates from three business segments, Pharmaceuticals, Animal Health, and a third one that contains "Corporate & Other." The Pharmaceuticals business offers human health products for the treatment of cardiovascular diseases, central nervous system disorders, arthritis and pain, infectious and respiratory diseases, urogenital conditions, cancer, eye disease, endocrine disorders, and allergies, among others. Pfizer is well known fbr its pre- scription medicines and the many over-the-counter medical products it offers. The over- the-counter self-medications range from oral care, upper respiratory health to tobacco dependence, skin and eye care, and hair growth. The Animal Health division offers medi- cines for livestock and pets. The company also manufactures empty gelatin capsules and engages in producing contract and bulk pharmaceuticals/chemicals, which it classifies under "Corporate/other" business. The company's revenues by segment are provided in Exhibit 3 and reveal that the Pharmaceuticals business dorninates the portfolio with over 90 percent of the revenues gen- erated each year, whereas the Animal Health division accounts for only 5 percent each year. The "Corporate/other" segment is the smallest of all, with less than 3 percent of total sales. Pfizer's international operations contributed $27.9 billion in revenues in 2008 as opposed to the $20.4 billion generated in the United States. Exhibit 4 provides detailed statistics of revenues by business segment and geographic region. This exhibit indicates that the dou- ble-digit declines in U.S. sales of Pharmaceuticals have been off'set by double-digit growth in international sales. From Case 25 of Strategic Management: Concepts and Cases.l3le. Fred R. David. Copyright O 201 I by Pearson Edr.rcation. Published by Prentice Hall. All rights reserved. ZY
Transcript
Page 1: Pfizer Case Study

Pfi zer, lnc. - 2009Vijaya NarapareddyUniversity of Denver

On May 9,2009, Japanese pharmaceutical manufacturer Eisai threatened Pfizer to termi-nate its long-standing partnership on the news of Pflzer's proposed acquisition of Wyeth.Eisai's venture with Pflzer dates back to the mid-1990s when Pfizer entered into an

alliance to sell Eisai's Aricept, the world's leading medicine fur the treatment ofAlzheimer's disease. Headquartered in New York City, Pfizer generated about $482 mil-lion in 2008 from the sale of Aricept, an increase of 20 percent fiom 2007, as shown inExhibit l. Pflzer vows to fight back, claiming that Eisai lacks any legal basis for termina-tion of their alliance.

Pfizer engages in the discovery, development, manufacture, and marketing of prescrip-tion medicines for humans and animals worldwide. Some of its well-known drugs are Lipitor,Viagra, Lyrica, Zeldox, and Aricept used for people, as well as Draxxin used fbr cattle.

The proposed Ptizer acquisition of Wyeth, a company based in Madison, New Jersey, for acash and stock purchase of $68 billion would enable Pflzer to diversity its product offer-ings and make further inroads into emerging markets. Exhibit 2 provides details of the ben-efits of the proposed Wyeth acquisition.

Pfizer operates from three business segments, Pharmaceuticals, Animal Health, and a thirdone that contains "Corporate & Other." The Pharmaceuticals business offers human healthproducts for the treatment of cardiovascular diseases, central nervous system disorders,arthritis and pain, infectious and respiratory diseases, urogenital conditions, cancer, eyedisease, endocrine disorders, and allergies, among others. Pfizer is well known fbr its pre-scription medicines and the many over-the-counter medical products it offers. The over-the-counter self-medications range from oral care, upper respiratory health to tobaccodependence, skin and eye care, and hair growth. The Animal Health division offers medi-cines for livestock and pets. The company also manufactures empty gelatin capsules andengages in producing contract and bulk pharmaceuticals/chemicals, which it classifiesunder "Corporate/other" business.

The company's revenues by segment are provided in Exhibit 3 and reveal that the

Pharmaceuticals business dorninates the portfolio with over 90 percent of the revenues gen-

erated each year, whereas the Animal Health division accounts for only 5 percent each year.

The "Corporate/other" segment is the smallest of all, with less than 3 percent of total sales.

Pfizer's international operations contributed $27.9 billion in revenues in 2008 as opposedto the $20.4 billion generated in the United States. Exhibit 4 provides detailed statistics ofrevenues by business segment and geographic region. This exhibit indicates that the dou-ble-digit declines in U.S. sales of Pharmaceuticals have been off'set by double-digit growthin international sales.

From Case 25 of Strategic Management: Concepts and Cases.l3le. Fred R. David.Copyright O 201 I by Pearson Edr.rcation. Published by Prentice Hall. All rights reserved. ZY

Page 2: Pfizer Case Study

Revenues

PRODUCT

PFtZER. rNC. - 2009

by Key Products ($ in millions)-continued

PRIMARY INDICATIONS YEAR ENDED DECEMBER 31 % CHANGE

2008 2007 08/07 07to62006

All other:

ZyfieclzyfiecDAlliance revenues

Allergies

Alzheimer's disease (Aricept),neovascuiar (wet) age-relatedmacular degeneration (Macugen),Parkinson's disease (Mirapex),hypertension (Exforge andOlmetec), multiple sclerosrs(Rebil) and chronic obstructivepulmonary disease (Spiriva)

129

2,251

1,541

r,189

1,569

1,314

/o?\,\A

(2)

JU

(a) Represents direct sales under license agrcement with Eisai Co., Ltd. Certain amounts and percentages may reflect rounding adjustments

Sottrce: Pfrzer's2008 Fctnn 10k,

The Proposed

Wyeth diversifies offering

Pharmaceuticals. Primary care. Specialty Care. Oncology. Established Products

Research. Pf lizer Global R&D

Market presence. Significant in Emerging

lvlarkets

Soirrce. www.phzer.com

Wyeth Merger Benefits to Pfizer

and expands presence in EMS

Biopha rmaceutica ls. Primary care. Soecialtv Care

F - VaccinesF - BioloqicsO . arnrntnav

7- Diversified businesses

, . Animal Healthtr ' Lapsugel

. Consumer Healthb . Nutritional Health

.N RacorrrhE .';;;;; Therapeutics Research Group

. Bio Therapeutics Research Group

Market presence. Enhanced in Emerging Markets

2006

Total Revenues by Business Segment

20072008

Pharmaceuticals

Animal Health

Corporate Other

TOTAL REVENUES

91.57c

5.87o

2.7%

100.jVc

91.8Vo

5.47o

2.87o

l00.j7o

93.2Vo

4.8Vo

2.070

100.OVa

Sor.trce: Pfrzer AnnuaL Report (2008'1.

Operating a global business is associated with complex challenges. In addition to multi-ple and diverse regulatory environments to contend with, global companies like Pfizer are

subject to unexpected changes in revenues and profits resulting from unpredictable cunencyfluctuations. Pfizer's income statement is provided in Exhibit 5. Note that Pfizer's sales in 2006,200'7,afi 2008 were approximately $48.37 billion, $48.42 billion, and $48.3 billion, respec-

tively. During the same time period, Pfizer's net income was $19.34 billion, 118.14 billion,and $8.10 billion, respectively. Note that Pfizer's Research & Development expenditures rose

$7.6 billion in 2006 to $7.9 billion in 2008, whereas Selling, General, and Administrative(SG&A) expenses declined from $15.59 billion in 2006 to $14.54 billion in 2008.

21

Page 3: Pfizer Case Study

PFTZER, tNC, - 2009

Pfizer's consolidated Balance Sheet in Exhibit 6 reveals that total assets shrunk

fiom $114.84 billion in 2006 ro $111.15 billion in 2008, and total liabilities increased

lrom $43.48 billion in 2006 to $53.59 billion in 2008. Note that total stockholders' equity

iell 19.34 percenr, from $71 .36 billion in 2006 to Xi57.56 billion in 2008.

Pfizer faces high competition in all its business segments due to the presence of many play-

ers, large and small, in the industry. Bayer AG, Merck & Co., and Novartis AG are Pfizer's

direct competitors in the pharmaceutical industry. Of the four maior players in the pharma-

ceutical industry, Ptizer and Merck are American companies Bayer is German, and

Novartis is Swiss. A comparison of key indicators included in Exhibit 7 shows that Pfizer

leads the pack, with Novarlis trailing closely behind.

With $97.13 billion in market capitalization, Pfizer is the largest company in this

strategic group. It has 80,250 employees, second to Novarlis, but it is the leader in revenues

($1'7.32 biilion), gross margins (85.86 percent), operating margins (36.13 percent), and net

income of $7.96 billion. However, note that Pfizer has the lowest earnings per share

($1.23) and price-earnings (PlE) ratio among its direct competitors.

The Wyeth acquisition is fraught with potential risks. First and foremost, there are severai

regulatory hurdles to overcome not only from regulators in the United States, but also over-

seas. Some of these approvals include the expiration or termination of the waiting period

under the Hart-Scott-Rodino Act, a decision to be issued by the European Commission

under the EC Merger Regulation declaring that the proposed merger is compatible with the

Common Market, and the approval of the proposed acquisition under the China Anti-Monopoly Law and by regulators in Canada and Australia as well'

The acquisition would also increase Pfizer's debt because it is set to take on about

$i22.5 billion of debt in addition to assuming Wyeth's debt. Servicing this much additional

debt is a risky move for Pfizer, which experienced a decline of revenues from $48.42 billiontn2007 to $48.3 billion in 2008.

Assuming the merger agreement moves forward unencumbered, Pfizer will assume

all responsibilities for pending litigation facing Wyeth. Like other companies in the indus-

try, Wyeth is currently facing various iawsuits and litigation claims related to patents,

product liability, consumers, commercial, securities, environmental and tax laws, and

government investigations. Outcomes of these pending claims can overburden Pfizer and

mitigate potential benefits fiom the Wyeth acquisition.Pfizer also faces iitigation in several courts around the world. For example, Pfizer is

in a contentious battle in a Jamaican court to protect its patented medication amlodipine(Norvasc) used for treating high biood pressure to avoid complications of severe conges-

tive healt failure, stroke, renal failure, and other vascular complications due to hyperten-

sion. The company is fighting the Jamaican court's decision that Pfizer's patent on its drug

expired in Jamaica as it had expired in other countries.

At home, Pfizer spent about $900 million in June 2008 to settle pending U.S.

consumer fraud-related class action lawsuits and personal injury claims involving

Celebrex and Bextra. Several ofPfizer's key products are slated to expire in the near future,

as indicared in Exhibit 8.

As shown in Exhibit 9, Pfrzer is determined to become the leading biopharmaceutical com-

pany in emerging markets through bold and innovative parlnerships.

In addition to traditional partnerships, alliances, mergers and acquisitions, Pfizer

recently partnered with world-c1ass foundations and nonprofit organizations like the

Grammeen Foundation in Bangladesh, whose founder is Mohammad Yunus, the recipient

of the Nobel Peace Prize in 2006 for his efforts in alleviating poverty through micro-financing. Pfizer recently entered into a partnership with Grammeen Health, an affiliateof Grammeen Foundation, to bring sustainable health-care delivery models that address

Page 4: Pfizer Case Study

PFTZER, rNC. - 2009

Overview of Direct Competitors

Pf izer Merck Novartis Industry

Market Cap

Employees

Revenue

Gross Margin

Operat. Margins

Net Income

EPS

91.138

80,250

41.328

85,8670

36.l37a

79681.193

52.31B

54,1 00

23.418

76.03Vo

25.53V0

5.93B

2.185

86.79B

98,000

42.298

73.107o

2l.60Vo

1.'798

J.+J

13.99l0rl

33s

253.49M

7l.00Vo

5.89V0

NiAN/A

Source: Cornpany Form l0kReports

Drug

Pfizer's Product Patent Expirationlnformation

U.5. Basic Product PatentExpiration Year

Aricept

LipitorXalatan

Geodon

Viagra

Detrol

Celebrex

Zyvox

Lyrica

Chantix

Seizentry

Sutent

Source: SEC Form l0K, February 21,2009

20lo20 t02011

2012

20t22012

20r42015

2018

2020

2021

202r

Pfizer's Mission and Vision inEmerging Markets

ffi 1;; ; ; ;;;";;;;;;;;;;;;- --lffi]H n*"0* of patrents In Emerging lvlarkeis rround the r,vorld in

{

ffi$ on innovative. socially resFansibie and c*mtnercialiy i

iffiil"o'" *nn''. _

We w!11...

iI:vt:ii,i bolcl shl innovalive irnr t']rr:i1i!s

r!:i{rh O:rtirnis r.r l,.1vr.r qEver feaeheal llefor€

lfavldB n.:il[ili9.,.]!rd:tlliigi In 6f affcrdable nlrnoi

li! ttc)qil:z.:d lor lrirrnrq it'! bgsr talent rrr areiilthcare

1*.trr::c a leading biopharmaceuliEal conrpary ir F!!r.rri,lin$ trlnrka:i:;

S o u rc e : w w w.pftzelcom

?6

Page 5: Pfizer Case Study

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-snroJ oslu ,^Aou eJe stuJg l€^rJ stl puu rezg6 'eldoed sselc-.reddn pu€ -elpplul uo Sutsnco3

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5002 - )Nr 'uSzlld

Page 6: Pfizer Case Study

Revenues

PRODUCT

PFIZER, INC. _ 2OO9

by Key Products ($ in millions)

PRIMARY INDICATIONS YEAR ENDED DECEMBER 31 % CHANGE

2008 2007 2006 08t07 07t06

Cardiovascular & metabolic diseases:

LipitorNorvasc

Chantix/Champix

Caduet

Cardura

Central

Lyrica

Reduction of LDL cholesterol

Hypertension

An aid to smoking cessation

Reduction of LDL cholesteroland hypertension

Hypertension/Benign prostatichyperplasia

(2) (2)

(2s) (38)

(4) 173

454

nervous system disorders:

$ 12,401

2,244

846

589

499

2,573

1,007

q 1' 675

3,001

883

568

506

I R?q

854

$ r2,886

4,866

101

370

538

I ,156

7s8

(6)

58

(t )

41

i8Geodon/Zeldox

Zoloft

Aricept(a)

Neurontin

Xanax/Xanax XR

Relpax

Arthritis and pain:

Celebrex

Epilepsy, post-herpetic neuralgiaand diabetic peripheralneuropathy fi bromyalgia

Schizophrenia and acute manicor mixed episodes associatedwith bipolar disorder

Depression and certain anxietydisorders

Alzheimer's disease

Epilepsy and post-herpeticneuralgia

Anxiety/Panic disorders

Migraine headaches

Arthntis pain and inflammation,acute pain

539

482

387

350

321

2,489

1,1 15

743

429

373

1,934

1,214

847

563

465

1,745

898

531

401

431

325

-tlf

2,110

358

496

316

286

( t0)

8

z

(13)

10

2 (.7 s)

20 12

t ton

944

632

438

4t5

1,764

1,190

581

969

401

t,604

843

, o?q

182

515

638

1,657

l,100

219

903

320

1,453

'795

t2

Infectious &Zyvox

Vfend

Zithromax/Zmax

Diflucan

Urology:VagraDetrol/Detrol LA

Oncology:

Sutent

Camptosar

Aromasin

Ophthalmology:

Xalatan

Endocrine disorders:

Genotropin

respiratory diseases:

Bacterial infections

Fungal infections

Bacterial infections

Fungal infections

Erectile dysfunction

Overactive bladder

Advanced and/or metastatic renalcell carcinoma (mRCC) andrefractory gastrointestinal stromaltumors (GiST)

Metastatic colorectal cancer

Breast cancer

Claucoma and ocular hypertension

Replacement of human growthhormone

18 21

18 23

(2) (31)

(10) (5)

10628

(42)

16

q

16646

7

25

10

66continued

CU

Page 7: Pfizer Case Study

Revenues

(ln millions of $)

PFtZER, tNC. - 2009

by Business and Geographical Segment

u.5. INTERNATIONAL

Year ended Dec.31, 2008 2007 2006 2007 2006

Pharmaceuticals

Animal Health

Corporate/Other

TOTAL

$ 18,851

1,168

416

$ 20,435

$ 21,s48

1,132

473

$ 23,153

$ 24,503

1,032

281

$25,822

q ?{ ?r1

r,657

881

$ 27,861

$22,8161,507

882

$25,265

$ 20,s80| 1'70

690

$ 22,549

ANNUAL PERCENTAGE CHANGES

WORLDWIDE TOTALS U5 INTERNATIONAL

% CHANGE 2008t07 2007to6 2008t07 2007t06 2008t07 2007106

Pharmaceuticals

Animal Health

Corporate/Other

(1)

7

(l)14

( 13)

3

(12)

(.12)

10

(10)

11

l010

31-Dec-07

11

18

12

31-Dec-06

Source: Pfrzer Annual. Report (2O08).

PERIOD ENDING

Pfizer's Income Statement (in thousands)

31-Dec-08

Total Revenue

Cost of Revenue

Gross ProfitOperating Expenses

Research Development

Selling General and Administrative

Non Recurring

Others

Total Operating Expenses

Operating Income or Loss

Income from Continuing Operations

Total Other Income/Expenses Net

Earnings Before Interest and Taxes

Interest Expense

Income Before Tax

Income Tax Expense

Minority Interest

Net Income from Continuing Ops

Non-recurring Events

Discontinued Operations

Extraordinary Items

Effect of Accounting Changes

Other Items

Net Income

Preferred Stock and Other Adjustments

Net Income Applicable to Common Shares

Source: Pfrzer's2008 Form l0k.

$48,296,000

8,112,000

40,184,000

7,945,000

14,537,000

3,308,000

2,668,000

28,4s8,000

1r,726,000

( 1 ,5 16,000)

10,210,000

516,000

9,694,000

1,645,000

(23,000)

8,026,000

78,000

8,104,000

$ 8,104,000

48,418,000

11,239,000

37,179,000

8,089,000

15,626,400

2,817,000

3,128,000

29,660,000

7,519,000

2,156,000

9,675,000

397,000

9,278,000

1,023,000

(42,000)

8,213,000

(69,000)

8,144,000

$ 8,144,000

48,371,000

7,640,000

40,731,000

7,599,000

15,589,000

2,1s8,000

3,261,000

28,607,000

t2r124,000

1,392,000

13,516,000

488,000

13,028,000

1,992,000

(12,000)

1 1,024,000

8,313,000

19,337,000

$ 19,337,000

32

Page 8: Pfizer Case Study

PFTZER, rNC. - 2009

Pfizer's Balance Sheet

(all numbers in thousands)

PERIOD ENDING 31-Dec-08 31-Dec-O7 31-Dec-06

Assets

Current Assets

Cash and Cash Equivalents

Short Term Investments

Net Receivables

Inventory

Other Current Assets

Total Current Assets

Long Term Investments

Property Plant and EquiPment

Goodwill

Intangible Assets

Accumulated Amortization

Other Assets

Deferred Long Term Asset Charges

Total Assets

LiabilitiesCurent Liabilities

Accounts PaYable

Short/Current Long Term Debt

Other Current Liabilities

Total Current Liabilities

Long Term Debt

Other Liabilities

Def'erred Long Term Liability Charges

Minority Interest

Negative Goodwill

Total Liabilities

Stockholderso EquitY

Misc. Stocks Options Warrants

Redeemable Preferred Stock

Preferred Stock

Common Stock

Retained Earnings

Treasury Stock

Capital Surplus

Other Stockholders' EquitY

Total Stockholders' EquitY

Total Liabilities and SE

$ 2,122p00

22,433,000

13,992,000

4,529,000

43,076,000

11,478,000

13,287,000

2r,464,000

l',t,'72r,000

4,122,000

$ 111,148,000

3,406,000

22,686,000

9,843,000

5,416,000

5,498,000

46,849,000

4,856,000

15,734,000

2l,382,000

20,498,000

1,844,000

4,105,000

115,268,000

1,827,000

26,400,000

9,392,000

6,1 1 1 ,000

3,219,000

46,949,000

3,892,000

16,632,000

20,876,000

24,350,000

2,138,000

114,837,000

6,233,000

9,320,000

11,4s6,000

27,009,000

14,53 r ,000

8,909,000

2,959,000

184,000

53,592,000

73,;443,000

49,142,004

(s7,391,000)

70,283,000

(4,994,000)

57,556,000

$ 111,148,000

7,78',7,000

s,825,000

8,223,00O

21,835,000

7,314,000

13,299,000

7,696,000

114,000

50,258,000

93,000

442,000

49,660,000

(s6,847,000)

69,913,000

1,749,000

65,010,000

115,268,000

t2,443,000) 4\40,0,0

6,512,000

21,389,000

5,546,000

8,529,000

8,015,000

43,479,000

141,000

441,000

49,669,000

(46,740,000)

69,104,000

(1,2s7,000)

71,358,000

114,837,000

34

Page 9: Pfizer Case Study

PFtZER. tNC. - 2009

the needs o1'4 billion people worldwide with incomes of less than $3,000 a year. Anotherinnovative partnership involves Pflzer and PlaNet Finance, which is examining ways inwhich health-care access mav be exoanded in China.

In May 2009,Pfizer announced it was giving away more than 70 of its most widely pre-scribed drugs, including Lipitor and Viagra, tbr up to a year to people who have lost jobsin calendar 2009 and had been taking the drug for three months or more. "Everybodyknows now a neighbor, a relative who has lost their job and is losing their insurance.People are definitely hurting out there," Dr. Jorge Puente, Pfizer's head of pharmaceuticalsoutside the United States and Europe, told the Associated Press in an exclusive interview."Our aim is to help people bridge this point."

The 70-plus drugs covered in the new Pfizer program include several diabetes drugsas well as some of Pflzer's top money makers, from cholesterol fighter Lipitor topainkiller Celebrex. Also included are fibromyalgia treatment Lyrica and also Viagra,used lbr male erectile dysfunction. The new Pfizer program includes some antibiotics,antidepressants, heart medications, contraceptives, and smokin-e cessation products.Cheaper generic versions are available for most of the drugs. The new program will likelyhelp prevent patients from switching to cheaper brands or generics through the worst ofthe recession and could help retain those taking top-seller Lipitor, which will begin com-peting wlth generic versions in 2010. Many analysts contend that the giveaway is a bril-liant marketing move that will generate low-cost publicity, build consumer loyalty, andkeep inventory from piling up.

In September 2009,Pftzer agreed to pay a record $2.3 billion to settle civil and criminalcharges over marketing of its recalled Bextra arthritis drug and three other medicines. Thecharges involved representatives ofPfizer promoting dlugs for conditions that they had notbeen approved for and giving doctors kickbacks to encourage them to prescribe the med-ications. This is the largest such settlement in the United States for claims o1'off-label drugpromotion, topping the $ I .42 billion Eli Lilly (LLY) agreed to pay earlier in 2009 for off-lable sales of its Zyprexa schizophrenia drug. Moreover, the $1.3 billion criminal penaltyrelated only to Bextra is "the largest criminal fine ever imposed in the United States for any

matter," according to the U.S. Department of Justice. The settlement also involves pain

management pill Lyrica, the schizophrenia treatment Geodon, and the anti-infection drugZyvox, as well as nine other medicines.

The world's biggest drugmaker, Pfizer spent nearly $5.6 million lobbying the U.S.government in the second quarter of 2009 on health-care reform, government spending onmedication, and patent and trade issues, according to a recent disclosure report. Pfizernearly doubled its lobbying spending from the $3.1 million in the year-ago period. Thecompany lobbied on legislation on numerous health refbrm provisions, including healthinsurance, information technology, electronic prescriptions, drug pricing, allowing genericversions of expensive biologic drugs, and requiring research comparing the effectivenessof medications and other types of treatment as well as on U.S. patent reform and on inter-national patent, market access, and regulatory issues involving at least 20 countries.

Drug firms are reducing, not adding, to their sales forces. By the end of 2008, the numberof pharmaceutical sales representatives in the United States had decreased to 90,000 froma high of about i 06,000 in 2006. In early 2009, Amylin Pharmaceuticals cut 35 percent ofits sales force, or 200 representatives.

For the tlrst time in fifty years, sales of prescription drugs in the United States

declined in 2009 fbr a variety of reasons. The United States has historically been the indus-

try's largest and most profitable area, but now drug companies are looking more and more

to developing countries such as Venezuela. Sales of prescription drugs in developing or

emerging markets increased to $152.7 billion in 2008, up fiom $67.2 billion in 2003. This

JO

Page 10: Pfizer Case Study

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