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Polyadenylation and Termination

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Polyadenylation and Termination. *CstF *CPSF *PAP *PABP. Torpedo model for transcription termination. RNA processing in eukaryotes. Addition of poly A tail Addition of 5’cap Splicing. Polyadenylation. *CstF *CPSF *PAP *PABP. Transcript Processing. Formation of the 5’ cap - PowerPoint PPT Presentation

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guanylyl transferase

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Polyadenylation and Termination *CstF *CPSF *PAP *PABP

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Page 1: Polyadenylation and Termination

Polyadenylation and Termination

*CstF

*CPSF

*PAP

*PABP

Page 2: Polyadenylation and Termination

Torpedo model for transcription termination

Page 3: Polyadenylation and Termination

Polyadenylation

*CstF

*CPSF

*PAP

*PABP

RNA processing in eukaryotesAddition of poly A tail

Addition of 5’cap

Splicing

Page 4: Polyadenylation and Termination

Formation of the 5’ cap

*RNA triphosphatase

*guanylyl transferase

*methyl transferase

Transcript Processing

Page 5: Polyadenylation and Termination

Functions of the Cap

ProtectionTranslatability TransportSplicing

Page 6: Polyadenylation and Termination

Splicing

Page 7: Polyadenylation and Termination

Spliceosome-mediated splicing

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