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INGOLD Leading Process Analytics Process Analytics Solutions for Biotechnology and Pharmaceutical Applications
INGOLDLeading Process Analytics
Process Analytics Solutions for Biotechnology and Pharmaceutical Applications
Our industrial solutions cover the diverse steps in a host of manufacturing processes. Solutions range from receiving raw materials through various manufacturing processes, in-line process controland end-of-line packaging control, to logistics and shipping. These solutions are integrated into the customer's IT environment, helping automate their workflows.
METTLER TOLEDO instruments are used in research, scientific, drug discovery, and quality control labs,amongst many others in the pharmaceutical, chemical, food&beverage and cosmetics industries.
METTLER TOLEDO invests between USD 60 and 70 million per year in R&D, having increased the R&D spending by an average of more than 10% each year for the past five years. METTLER TOLEDOhas an outstanding reputation as a global innovator. It also has highly specialized know-how in the field of automation and robotics, miniaturization, software development, as well as optical- and laser-based applications. METTLER TOLEDO is committed to total quality management and ISO standards and compliance with industry regulations.
Within the METTLER TOLEDO group, the Process Analytics division focuses on analytical measurementsolutions for industrial production processes. The division is comprised of two long-standing businessunits – INGOLD and THORNTON – which are recognized as leaders in the markets they serve.
Dr. Richard D. Thornton, a professor at the Massachusetts Institute of Technology (MIT), founded Thornton Inc. in 1964. THORNTON develops, manufactures, markets and services innovative analyticalinstruments and sensors for measurements in pure and ultrapure water applications with such para-meters as resistivity/conductivity, DO, flow, pressure, pH / ORP, temperature and TOC (Total OrganicCarbon).
For nearly forty years THORNTON has been recognized as the technology leader by defining the most accurate resistivity measurement of ultrapure water. THORNTON works closely with customers and international organizations, such as USP, EP, JP, FDA, ASTM in establishing industry standards for thepharmaceutical, semiconductor and power industries.
Premier international pharmaceutical manufacturers and global water system fabricators prefer innova-tive products from THORNTON.
METTLER TOLEDO – dedication to innovation and quality.
METTLER TOLEDO GROUP.
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METTLER TOLEDO is specialized in the area of precision instruments and offers the most comprehensive range of services on a global level. With more than 8,000 employees, the company generates annual sales of over USD 1 billion. Mettler-Toledo International Inc. has been listed on the New York Stock Exchange since 1997.
THORNTON – Leading Pure Water Analytics.Thornton Inc. was acquired in 2001 and is now the second member of the Process Analytics divi-sion. THORNTON continues to focus on pure and ultrapure water measurement systems, comple-menting INGOLD’s in-process measurement solutions.
INGOLD has a long history of innovations, starting with Dr.Ingold’s invention of the pH combinationelectrode, the first sterilizable pH electrode produced for the pharmaceutical industry. The INGOLD pH,DO, CO2, conductivity and turbidity product lines firmly establish Mettler-Toledo GmbH as a worldwideleader for process analytical measuring systems in chemical, food & beverage, biotechnology andpharmaceutical industries meeting the challenging requirements of modern industrial liquid processes,INGOLD introduced hygienic sterilizable pH, oxygen, CO2 and turbidity sensors, and set industry stan-dards with its famous INGOLD socket for fermentation vessels and the IP 68 VP connector for watertightinstallations. Our latest innovation was the industry sterilizable dissolved CO2 measuring system whichnow helps customers to optimize their cell cultures.
INGOLD is well known for its long experience in offering reliable quality measurement solutions for biotechnology and pharmaceutical applications which ensure an optimal yield and low overall costs for our customers.
Fermentation control with pH, CO2 and DO, see p.6
pH is the most important quality parameter for cell and bacte-rial growth, metabolic activity and final products in bacterialfermentation or cell culture processes.DO and CO2 control, on the other hand, is critical for anoptimized growth environment and hence for yield. Provenhygienic design, withstanding repeated sterilization / auto-clave treatment is indispensable for protection of valuablefermentation batch contents.INGOLD’s long-life sensors with minimum drift provide highlyaccurate and reproducible measurements and offer an idealtool to optimize yield and overall cost-of-ownership.
Cell growth monitoring with turbidity sensors, see p.7
One of the most important parameters when monitoring mammalian cell processes in bioreactors, is cell density.INGOLD’s sterilizable turbidity sensors offer reliable and accurate inline monitoring of cell growth, thus providing thebasis for achieving higher viable cell densities at reducedmedium consumption.
In addition to our measurement equipment we help our customers tocomply with regulations and integrate into process control systems:
• FDA compliant services, see p.13
• Compliance with regulations, see p.14
INGO
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INGOLD – Leading Process Analytics.
Founded in 1948, Ingold AG became part of Mettler AG in 1986, forming the cornerstone of the Mettler-Toledo Process Analytics division.
METTLER TOLEDO products ensure safety and reliable top performance throughout a plant.
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pHDOTurbidityCO2
pHConductivity Resistivity
pH
Culture Propagation Media Makeup
Process Preparation
Inoculum Tank
EffluentTreatment
PlantWaterCycle
WaterPreparation
Downstream Processes
Fermentation/Synthesis
Water preparation Fermentation, p.6
Synthesis, p.8
pHConductivityTurbidity
pHDOConductivityTurbidity
Synthesis Reactor
Final Products
Fermentation
Drying
Waste Water Tank
Crystallization
Filtration
Separation
Effluent Treatment, p.12Downstream processes, p.10
High product yield with INGOLD quality products.
A complete range of sterilizable andautoclavable pH electrodes with lowdrift and long serviceable life
Combined pH/temperature electrodes
The highly versatile solution provider,InPro 2000 Series, is particularly sui-table for high accuracy requirementsdue to a flowing liquid junction.
The low-maintenance pH electrodesInPro 3100 with high pressure resis-tance and InPro 3253 with unmatchedstability performance.
Non-glass pH electrode
The highly robust non-glass electrodeInPro 3300 based on ISFET technologyoffers fast response time and EHEDGcertified hygienic design.
CO2 In-situ monitoring
The new InPro 5000 CO2 sensorfeatures hygienic design and accuratein-situ monitoring, specially required foroptimized fermentation with mam-malian cells.The transmitter CO2 5100e offersdiagnostic information, two currentoutputs and integrated PID controller.
For more than 50 years Mettler-Toledo Ingold has actively engineered new products to meet thedemands of our customers to improve their process efficiency and to comply with FDA and GMPregulations. A wide range of hygienic measurement solutions with sterilizable / autoclavable pH,DO and turbidity sensors helps our customers controlling and optimizing fermentation and cell culture processes.
Enhanced performance and un-matched hygienic design
The InPro 6800 DO sensor for use inbiotechnology applications is availablecomplete with EHEDG, 3-A and 3.1Bmaterial certificates. The service-friendlydesign of the inner body guarantees anoptimal cost of ownership.
«Advanced line» transmitters for pH, DO and CO2
The pH 2100e and O2 4100e areadvanced performance transmitters withtwo current outputs and PID controller.A unique sample calibration routine secures a highly accurate measure-ment, particularly in long lasting batch-es. Two wire units in Ex and non-Exversions are both available with HART®,PROFIBUS® and FOUNDATION Fieldbusinterface in Ex.
pH measurements DO measurements
Sterilizable retractable housings
The enhanced retractable housings InTrac 796e/797e/799e are designed for sterilization of gel- and liquid-electrolyte pH electrodes as well as for DO and turbiditysensors and turbidity sensors and other in-situ sterilization of electrodes/sensors
The TriLock™ system guarantees:• safe insertion into process • safe withdrawal of sensors• sensor exchange during ongoing
process
The InTrac 798 is suitable for 120 mm pH electrodes, withenhanced safety and cleanability features (EHEDG tested).
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CO2 measurements
A unique cell growth monitoring system
The easy-to-handle turbidity transmitter Trb 8300 is equippedwith application-specific parameter sets, offers linearity overa wide range of concentration, and an easy-to-use calibra-tion routine, ProCal.
The sterilizable turbidity sensor family InPro 8100/8200functions on the principle of backward scattering of light.These sensors cover a wide measuring range with an extra-ordinary linearity up to high concentrations.
Turbidity measurements Versatile static housing family
InFit 761/764-50 CIP is a static housing family for the safe mounting ofgel- and liquid-electrolyte pH electrodesas well as of DO sensors.These housings feature a unique hygienic design with the use of FDA approved materials and EHEDG certificates.
Hygienic housings
Accurate and reliable measurements under harsh conditions.
pH electrodes – the right solution for every application
For the most demanding processes
Substantially prolonged operational life reduces maintenance and replacementcosts. The pH electrode InPro 4800 is designed for toughest applications and isresistant to particularly high operational pressures
The versatile proven industry leader
InPro 4250 is a high-performance, industrial pH electrode with enhanced Xerolyt®
Plus polymer electrolyte. Direct contact of sample media with the polymer electro-lyte ensures freedom from clogging. High resistance to solvents and acids.The InPro 3250 is particularly suitable for high accuracy requirements.
The selection is completed by
the liquid filled electrode type InPro 2000 (see p.6), a versatile solution providerwith high accuracy measurement, long life and double diaphragm option for appli-cations with high contamination potential.
Mettler-Toledo Ingold solutions cover a wide range of difficult operational conditions, such as those commonly found in chemical synthesis processes, e.g. in vitamin or hormone production.Our measurement systems are able to master the most demanding process environments ope-rating at high temperatures and pressures – the industrially proven equipment designs ensure long serviceable life and reliability for critical processes. Many products are available with inter-national Ex and pressure certificates to comply with plant safety requirements.
pH measurements
«Advanced Line» pH transmitters
The two-wire transmitter pH 2100e issuitable for highly reliable and accurate pH measurements in many industrialapplications. The package offers HART®
or PROFIBUS® and FONDATION Fieldbuscommunication in Ex and non Exversions.
Temperature-compensated pH electrodes – InPro 2000, 3000 and 4000 families.
The integrated temperature sensor provides you with the following benefits:
• elimination of calibration errors.
• more precise pH measurements.
• measurement of process temperature directly at the location of pH measurement.
The result:More accurate and reliable measurements with INGOLDtechnology!
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The versatile retractable housing
The enhanced InTrac7XXe housingfamily has been designed to meet thehighest standards of safety during on-line process measurement tasks. Theyprovide a straightforward means for theinsertion and withdrawal of sensorswithout any need to interrupt the on-going process plus TriLock™ for safety.These housings come complete with3.1B and ATEX/FM certificates.
EasyClean – a fully automated pHmeasuring solution
Our range of automated sensor clean-ing and calibration systems offerunique solutions for chemical process-es. This system is particularly suitablefor measurement points with frequentcalibration cycles and ensures more reliable measurements, and a longersensor life, leading to an improvedcost-of-ownership.EasyClean is perfectly complementedby the InTrac SL housing family, and isavailable in either Ex or non-Ex ver-sions.
Cleaning and calibration systems
Retractable housings
High quality products for cost-savingprocess efficiency.
Accurate and versatile low-mainte-nance electrode
The InPro 3250 is a enhanced pH elec-trode for a wide range of applications,and fully autoclavable or in-situ sterili-zable featuring high pressure specifica-tions. A solution ground option withenhanced diagnostics features is alsoavailable.
M 700 the versatile multichannelsolution.
The M 700 transmitter is a versatilemulti channel system and freely config-urable even on-site. It is available inhygienic design and comes with a widevariety in Ex and non-Ex versions andwith a wide variety of software options(21 CFR part 11, logbooks).
High process efficiency is a critical factor in separation, filtration, crystallization or drying in order to save costs and to improve yield.Compliance with FDA standards and CIP/SIP conditions are mandatory. Beyond that, low mainte-nance, rugged and versatile design as well as long serviceable life are other important require-ments to optimize overall cost-of-ownership.
CIP-applicable conductivity sensor
The InPro 7108 VP sensor is used formedium to high conductivity measure-ments. All sensors of this family areequipped with a built-in Pt1000 tem-perature sensor (RTD), and come with3.1B certificate.
Unique diagnostic features
The transmitter Cond 7100e covers a wide range of applications, with en-hanced safety features such as uniqueUSP 23 set points.The SensoCheck® feature allows pola-rization to be detected early and re-liably. Digital communication versionswith integrated HART®, PROFIBUS® orFOUNDATION Fieldbus protocols in Exand non-Ex are also available.
pH measurements
Conductivity measurements
IP 68 VarioPin connector – the new industrial standardfor all METTLER TOLEDO sensors
The rugged construction of the VarioPin connector provides users the watertightconnection of a fixed cable with the convenience of a detachable cable. TheVario Pin connector is tested to IP 68, ensuring that the connection is dust andsubmersion proof.
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Crystallization onset/filter break-through monitoring
The new easy-to-handle transmitter Trb 8300 is equipped with applica-
tion-specific parameter sets, and offers an unmatched
wide linearity, as well as an easy-to-use calibration routine.
Together with the high turbidity sensors InPro 8100/8200 the
system provides a highly accurate crystallization
onset monitoring system.For low turbidity monitoring e.g. forfilter breakthrough control the forward/sideward sensors are
the first choice.
Static state-of-the-art housing
InFit 761-25CIP, the modern statichousing for safe, quick and simplemounting of pH electrodes, DO andconductivity sensors with PG 13.5thread.InFit 761 meets the latest Europeanpressure directives and provides fullprocess safety with 3-A and EHEDGcertificates.
HousingsTurbidity measurements
Economic quality solutions from INGOLD.
Accurate pH measurement is important for determining thestate of the raw effluent, for controlling the dosage of chemi-cals in neutralization and other necessary chemical treat-ment steps, as well as for monitoring the quality of the finaldischarge.An efficient control of DO transfer into the treatment basins isrequired in order to enable aerobic microorganisms to decomposethe organic compounds. Our rugged measuring systems provide areliable solution to these demands.
Unique price/performance ratio
Designed for simultaneous measure-ment of DO and temperature values in the field of effluent treatment applica-tions, the InPro 6050 offers high andreliable performance.
The low-maintenance electrode
The InPro 3250 offers self-cleaning of the diaphragm, effected by the partlyflowing liquid junction, hence, long operational life in effluent applications.
The cost-effective polymer body electrode
The InPro 4010 with PSO body andpolymer reference electrolyte ensuresreliable measurements in contaminatedeffluents. The InPro 4500 as a 1"thread-in PVDF version is equipped with a flat membrane, a solutionground and offers a robust and easy-to-handle alternative.
Value Line transmitters
DO measurements
Turbidity measurements
pH measurements
The robust 4-electrode sensors
The InPro 7108/CPVC is used for reliable measurement from medium tohigh conductivity.
Conductivity measurements
The new low-cost polymer body sensor
InPro 8050 for high turbidity togetherwith the transmitter Trb 8300 are idealfor highly contaminated effluent appli-cations and offer easy and reliablemeasurement at reasonable costs.
Cost effective solutions for standard applications
These transmitters for pH, DO and conductivity are characterized by theirstraightforward installation, set-up andoperation. They offer two current out-puts and are available in panel- andwall-mount versions.
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Design qualification (DQ)In this very first step, the functional, operational and technical specification for a measuring point have to be defined. METTLER TOLEDO offers the requested certificates to proveproduct quality.
Installation qualification (IQ)Following basic installation and initial calibration, the mea-suring loop is ready for testing. All relevant data will berecorded in the EQ document provided by METTLER TOLEDOservice personnel.
Operational qualification (OQ)Before used in the process, the guaranteed performance has to be checked and recorded in the EQ document. A detailed operational qualification is the final touchstone forsuccessful system functionality.
FDA-compliant quality and services – making the difference.
High product quality in pharmaceutical applications can only be achieved if all the relevant stepsof a process are carefully defined and measuring results are precise and reproducible. Completedocumentation of each single step is of highest priority.METTLER TOLEDO has the knowledge to assist in equipment qualification (EQ) to meet the moststringent legal regulations.
Performance qualification (PQ)Periodically performed system tests guarantee proper func-tionality of a measuring loop. Results are protocolled in thelogbook and are key information for a traceable validation.
Maintenance qualification (MQ)METTLER TOLEDO will train personnel to set up a preventivemaintenance plan, indispensable for ensuring trouble-freeprocess operation.
Compliance tools and services are available as individualmodules or comprehensive packages.
With this package METTLER TOLEDO is able to provide cus-tomized validation services.
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METTLER TOLEDO
Global services
• Conductivity sensor calibration(NIST traceable)
• NIST traceable buffers• Validation support/consulting• Equipment qualification according to
the latest QM standards as definedby the responsible authority
• Sensor performance qualification
METTLER TOLEDO meets the latest standards of GMP and FDA guidelines.
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Compliance and enhanced safety – hygienic designby INGOLD including USP class VI.
It all started with the INGOLD socket and the 465 sterilizable pH electrode some decades ago. Today, METTLER TOLEDO has unrivalled in-depth experience in hygienic equipment design and aproven track record in meeting the most stringent FDA and GMP regulations.
Housings and sterilizable/autoclavable sensors suitable for CIP and SIP procedures in pharma-ceutical applications are core products of the INGOLD program.
INGOLD process adaptionsThe INGOLD safety weld-in socket is the optimized process adaption and offers thehighest possible level of safety. The optimal positioning of O-rings, makes themideal for use in combination with CIP/SIP approved housings.
Compliant with EHEDG, FDA, USP class VI and 3-A guidelinesHygienic CIP-housings are based on stringent design principles, are fully sterili-zable and fulfill the requirements of 3-A and EHEDG standards.They are available with 3.1B certificates for the housing material and FDA 21 CFR 177 compliant sealing/O-ring material as standard supply,on request even with USP class VI.
Smooth surfacesThe smooth surfaces of Mettler-Toledo Ingold CIP-housings prevent the adherence of microorganisms. CIP approved housings are produced either fromone single workpiece or have smooth, crevice-free welded seams. The materialsfulfill the requirements of AISI 316L.
Electrodes and sensors for CIP/SIP procedures complying with USP class VIMost INGOLD pH electrodes and DO sensors are designed to be sterilizable andautoclavable up to 140 °C (284 °F). Conductivity and turbidity sensors are alsosterilizable. O-rings exposed to wetted parts of DO and CO2 sensors comply withUSP class VI as a standard.
Documentation and certificatesAll applicable sensors and housings fulfill the new European pressure directive andare supplied with 3.1B certificate.A comprehensive selection of our instruments is 3-A and EHEDG certified and incompliance with GMP guidelines.
Advantages at a glance
• Process adaptions available forCIP and SIP applications
• CIP/SIP housings with unrivalledhygienic features
• CIP/SIP electrodes and sensors • FDA and EHEDG conformity, and
3-A standards
®
Smooth surface of an O-ring
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Safety weld-in socket
USP class VI
Switzerland / UrdorfHeadquarters of Process Analytics
USA / Bedford
China / Shanghai Brazil / São Paulo
Engineering-SpecBook with CD-ROM
Engineering of a new measurement loop is often a time-consuming task. This comprehensive book will make lifeeasier and help to find the best solution.
Distribution networkBased on its several global production sites, more than 20market organizations, and numerous sales representatives,METTLER TOLEDO maintains a wide distribution network allover the world. Satisfaction of our customers is based onthree pillars:
• Consulting: With the knowledge of our experts, we supportyou in finding the best solution, including planning,product selection, and installation of our measurementsolution.
• Top products: A complete range of products and systemsto meet measurement requirements
• After-sales service: With our customized, lifelong servicemanagement, we are able to assist in managing measure-ment loops throughout their whole life-cycle.
A worldwide network of experts at service.
METTLER TOLEDO provides full sales and service coverage worldwide. Wherever our customersare, we are the competent partner. Many global industrial manufacturers rely on our longstandingexperience.
Mettler-Toledo Process Analytics’ four producing organi-zations are close to our customers all over the world andprovide:• Faster logistics• Fast response time to market demands
Production sites
Sales and service ● Market organizations▲ Distribution partner
Wor
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Sales and Service:
AustraliaMettler-Toledo Ltd.220 Turner StreetPort MelbourneAUS -3207 VictoriaPhone +61 39 644 57 00e-mail [email protected]
AustriaMettler-Toledo GmbHFavoritner Gewerbering 17A -1100 WienPhone +43 1 604 19 80e-mail [email protected]
BrazilMettler-Toledo Ind. e Com. Ltda.Alameda Araguaia451 - AlphavilleBR - 06455-000 Barueri / SPPhone +55 11 4166 74 00e-mail [email protected]
ChinaMettler-Toledo Instruments(Shanghai) Co. Ltd.589 Gui Ping RoadCao He JingCN -200233 ShanghaiPhone +86 21 64 85 04 35e-mail [email protected]
CroatiaMettler-Toledo d.o.o.Mandlova 3HR -10000 ZagrebPhone +385 1 292 06 33e-mail [email protected]
Czech RepublicMettler-Toledo spol s.r.o.Trebohosticka 2283 /2CZ -100 00 Praha 10 Phone +420 2 72 123 150e-mail [email protected]
Mettler-Toledo GmbHProcess AnalyticsIm Hackacker 15P.O. BoxCH-8902 Urdorf, SwitzerlandTel. +41 44 736 22 11Fax +41 44 736 26 36E-Mail: [email protected]
DenmarkMettler-Toledo A/SNaverland 8DK -2600 GlostrupPhone +45 43 27 08 00e-mail [email protected]
FranceMettler-ToledoAnalyse Industrielle Sàrl30, Boulevard de DouaumontBP 949F -75829 Paris Cedex 17Phone +33 1 47 37 06 00e-mail [email protected]
GermanyMettler-Toledo GmbHProzeßanalytikOckerweg 3D -35396 GießenPhone +49 641 507 333e-mail [email protected]
Great BritainMettler-Toledo LTD64 Boston Road, Beaumont LeysGB - LE4 1AW LeicesterPhone +44 116 235 7070e-mail [email protected]
HungaryMettler-Toledo Kereskedelmi KFTTeve u. 41HU -1139 BudapestPhone +36 1 288 40 40
IndiaMettler-Toledo India Private LimitedAmar Hill, Saki Vihar RoadPowaiIN -400 072 MumbaiPhone +91 22 2857 0808e-mail [email protected]
ItalyMettler-Toledo S.p.A.Via Vialba 42I - 20026 Novate MilanesePhone +39 02 333 [email protected]
JapanMettler-Toledo K.K.Process Division5F Tokyo Ryutsu Center, Annex B6-1-1 Heiwajima, Ohta-kuJP -143-0006 TokyoPhone +81 3 5762 07 06e-mail [email protected]
MalaysiaMettler-Toledo (M) Sdn BhdBangunan Electroscon Holding Lot 8 Jalan Astaka U8 /84Seksyen U8, Bukit JelutongMY -40150 Shah Ahm SelangorMalaysiaPhone +60 3 78 45 57 73e-mail [email protected]
MexicoMettler-Toledo S.A. de C.V.Pino No. 350, Col. Sta.MA. Insurgentes, Col AtlampaMX - 06450 México D.F.Phone +52 55 55 47 57 00e-mail [email protected]
PolandMettler-Toledo (Poland) Sp.z.o.o.ul. Iwonicka 39PL - 02-924 WarszawaPhone +48 22 651 92 32e-mail [email protected]
RussiaMettler-Toledo ZAOSretenskij Bulvar 6/1Office 6RU -101000 MoscowPhone +7 095 921 92 11e-mail [email protected]
SingaporeMettler-Toledo (S) Pte. Ltd.Block 28Ayer Rajah Crescent #05-01SG -139959 SingaporePhone +65 6890 00 11e-mail [email protected]
SlovakiaMettler-Toledo s.r.o.Bulharska 61SK -82104 BratislavaPhone +421 743 42 74 96e-mail [email protected]
SloveniaMettler-Toledo d.o.o.Peske 12SI - 1236 TrzinPhone +386 1 530 80 50e-mail [email protected]
South KoreaMettler-Toledo (Korea) Ltd.Yeil Building 1 & 2 F124-5, YangJe-DongSeCho-KuKR -137-130 SeoulPhone +82 2 3498 3500e-mail [email protected]
SpainMettler-Toledo S.A.E.C/ Miguel Hernández, 69-71ES - 08908 L’Hospitalet de Llobregat(Barcelona)Phone +34 93 223 76 [email protected]
SwedenMettler-Toledo ABVirkesvägen 10Box 92161SE -12008 StockholmPhone +46 8 702 50 00e-mail [email protected]
SwitzerlandMettler-Toledo (Schweiz) AGIm LangacherPostfachCH - 8606 GreifenseePhone +41 44 944 45 45e-mail [email protected]
ThailandMettler-Toledo (Thailand) Ltd.272 Soi Soonvijai 4Rama 9 Rd., BangkapiKuay KwangTH -10320 BangkokPhone +66 2 723 03 00e-mail [email protected]
USA /CanadaMettler-Toledo Ingold, Inc.36 Middlesex TurnpikeBedford, MA 01730, USAPhone +1 781 301 8800Toll free +1 800 352 8763e-mail [email protected]
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Illustrations: INGOLD archive of Mettler-Toledo GmbH, p. 7 DSM Nutritional Products,pp. 16/17 Ciba Speciality chemicals
METTLER TOLEDO Market Organizations
Subject to technical changes.© Mettler-Toledo GmbH, Process Analytics05/04 Printed in Switzerland. 52 900 293
Management Systemcertified according toISO 9001 / ISO 14001
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ISO 14001certified
ISO
Mettler-Toledo GmbH, Process AnalyticsCH -8902 Urdorf, SwitzerlandTel. + 41 44 736 22 11, Fax + 41 44 736 26 36
Your METTLER TOLEDO contact:
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