PROJECT LIFE12 ENV/IT/000336 “Anti-infective environmental friendly molecules against plant...

PROJECT LIFE12 ENV/IT/000336

“Anti-infective environmental friendly molecules against plant pathogenic

bacteria for reducing Cu”“AFTER Cu”

Start: 01/01/2014End: 31/12/2015

2015, January 22ndIst year Meeting

FaenzaASTRA premises


AGENDAIst year meeting

TECHNICAL & PROGRESS MEETING• 15:00 [ASTRA] Welcome and opening of the meeting• 15:05 [All] Actions carried out by each partner (please prepare a ppt• presentation and include After-Cu logo and LIFE logo in each slide) and• scheduled activities from June 2014 until the end of December 2014.• 16:30 [All] Open discussion on actions carried out• 17:00 [All] After-Cu Technical future issues:• o [DISPAA] Technical activities scheduled in the next six months of the project• o [All] Open discussion on actions to be carried out in the next six months of the

project• 17:30 [DISPAA] Management and dissemination issues• 17:50 [All] General questions• 18:00 End of progress meeting

•


AFTER Cu – 1° year meetingFaenza – 2015, January 2015




Technical Actions carried out by each partner in the last six months

B.2: Demonstration of the qualitative and quantitative yields of conventional chemical synthesis and biotechnological synthesis of the anti-virulence peptides at laboratory scale

B.3: Demonstration of the chemical and biological stability of anti-virulence peptides produced by conventional chemical and biotechnological synthesis

B.4: Demonstration of Kilo-scale biotechnological synthesis of the anti-virulence peptides by recombinant technology

B.5(close start): Demonstration of the null toxicity profile of the anti-virulence peptides on model organisms and microorganisms

B.6 (close start): Demonstration of the anti-virulence peptides in vivo performances at pilot scale level in field screenings

B.7 (close start): Demonstration of the effectiveness of the anti-virulence peptides in the presence of contamination by copper compounds at pilot scale level in field screenings

.AFTER Cu – 1° year meetingFaenza – 2015, January 2015


Technical Actions carried out by each partner in the last six months

C.2: Monitoring of the in vitro anti-virulence performances of peptides at laboratory level

C.3: Monitoring of the absence of side effects for the anti-virulence peptides on common targets of any living organism at laboratory level

C.4 (start): Monitoring of the absence of a direct selection operated by the anti-virulence peptides towards the emergence of bacteria resistant to the anti-virulence peptides themselves at laboratory level

C.5 (start): Monitoring of the short term environmental benefits from the use of the anti-virulence peptides in plant disease control at pilot scale level in field screenings

C.6 (start): Monitoring of the absence of an indirect selection operated by the anti-virulence peptides on copper compound and antibiotic resistant bacteria at pilot scale level in field screenings

. AFTER Cu – 1° year meetingFaenza – 2015, January 2015


Presentations ofeach beneficiary

CEBAS CSIS ICCOM CNR

ASTRA SOLDANO DISPAA

.



Presentation of DISPAA

instruments and data referred toB2-B7 C2-C6

D actions

.




Psn (0,5) + Agro_Ap17

C-



Psn (0,05) + Agro_Li27

C-













….evaluated by Congo Red bioassay
















SAME STRATEGY APPLIED FOR AP17 AND Other PEPTIDES

WORK In progress



[All] Open discussion on actions carried out

.





Dissemination actions

D1 Demonstration workshop in Italy (last 6 months)D2 Demonstration workshop in Spain (last 6 months)D3 Project website (end M3)D4 Notice boards (end M3)D5 Layman's report (last 3 months)D6 Diffusion material preparationD7 Articles and press releasesD8 NetworkingD9 After Cu technology manual (last 9 months)D10 Demonstration workshop, seminars, conferences and other eventsD11 Dissemination to Institutions and policy makersD12 After-LIFE Communication Plan (last 3 months)D13 International fairs and other eventsD14 Digital supports for international diffusion



Dissemination actions carried out by each partner in the last six months



AFTER Cu Technical issues for the next six months…towards project conclusion..

B.2: Demonstration of the qualitative and quantitative yields of conventional chemical synthesis and biotechnological synthesis of the anti-virulence peptides at laboratory scale

B.3: Demonstration of the chemical and biological stability of anti-virulence peptides produced by conventional chemical and biotechnological synthesis

B.4 : Demonstration of Kilo-scale biotechnological synthesis of the anti-virulence peptides by recombinant technology

B.5: Demonstration of the null toxicity profile of the anti-virulence peptides on model organisms and microorganisms

B.6 : Demonstration of the anti-virulence peptides in vivo performances at pilot scale level in field screenings

B.7: Demonstration of the effectiveness of the anti-virulence peptides in the presence of contamination by copper compounds at pilot scale level in field screenings



AFTER Cu Technical issues for the next six monthstowards project conclusion..

C.2: Monitoring of the in vitro anti-virulence performances of peptides at laboratory level

C.3: Monitoring of the absence of side effects for the anti-virulence peptides on common targets of any living organism at laboratory level

C.4: Monitoring of the absence of a direct selection operated by the anti-virulence peptides towards the emergence of bacteria resistant to the anti-virulence peptides themselves at laboratory level

C.5: Monitoring of the short term environmental benefits from the use of the anti-virulence peptides in plant disease control at pilot scale level in field screenings

C.6 : Monitoring of the absence of an indirect selection operated by the anti-virulence peptides on copper compound and antibiotic resistant bacteria at pilot scale level in field screenings

C.7 (start ) Monitoring of technical-socio-economic assessment of the After-Cu project



After-Cu Technical future issues for the next six months

and

Open discussion on actions to be carried outin the next six months of AFTER Cu project



AFTER Cu Dissemination issues for the next six months

Discussion and Planning



ADMINISTRATIVE ISSUES

Next Deliverables Partner costs January 2015 Next meeting



Partner costs January 2015



Courtesy of E.Colombi, 2012

AFTER Cu – 12 month meetingASTRA – 2015, January 22nd

Happy 1° birthday

to

AFTER Cu!









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