Historical evidence
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ First description by Hippocrates in 4th century BC
§ Found in Egyptian mummy El Amrah
§ Sushrutha performed perineal lithotomy in 12 centry BC
Historical development
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ First open surgery for renal stone by Heinecke in 1879
§ Fernstrom and Johansson did the first PCNL in 1976
§ Chausy performed the first ESWL in 1980
Incidence
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ 12% have stone in their lifetime§ 12% of men will suffer from kidney
stone by age of 70§ 5% of women will suffer from kidney
stone by age of 70§ 50% have recurrence within 5-10 yrs§ 7-10 of every 1000 hospital admission
is of renal stone§ Highest incidence of kidney stone is in
30-45 years
Clinical Presentation
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ Renal Colic§ Hematuria [both microscopic
and macroscopic]§ Lower Urinary Tract Symptoms
[LUTS]§ Incidental finding§ Urinary Tract Infections§ Renal Impairment
The Indian Scenario
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ 1 out of 1000 Indians suffer from stone disease
§ More common in the stone belts [Maharashtra, Gujarat, Punjab, Haryana, Delhi and Rajasthan]
§ Studies have shown that they pass only about 1 to 1.5 liters of urine in these areas
The theories of Stone formation
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ Many substances are in super saturation [180 liters of blood to 2 literes of urine]
§ Most of the stones are by Idiopathic stone formers
§ Metabolic abnormalies too contribute to stone formation
The Metabolic abnormalities
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
SUSPECT IF§ Bilateral§ Recurrent§ Occur in the young age§ Are multiple
What happens?
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ Most of the small stones pass but some act as nidus
§ Some can fill the Kidney as Staghorn calclus
§ They can get blocked at various places causing symptoms
§ Stones in the bladder could cause retention of urine
Clinical Presentation
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ Incidental diagnosis on routine health checkups.
§ Dull aching pain in the back§ Acute colic.§ Classical pain is described as pain
from loin to groin, accompanied by nausea, vomiting and gaseous distension.
Clinical Presentation
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ Urinary tract infection.§ Increased frequency of urine§ Pain and or burning while
passing urine.§ Passage of blood in urine
(Hematuria) which can be gross or microscopic
Investigations
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ Urine microscopy.§ Urine Culture & Sensitivity § X ray KUB.§ Ultrasound abdomen
Investigations
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ Blood tests [Creatinine, Electrolytes]
§ Routine tests for surgical procedures
§ IVU or Intravenous Urography
Investigations for cause
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ Serum Calcium§ Serum Phosphorus.§ Serum Uric acid§ 24 hour urinary calcium / 24
hrs urinary uric acid§ Stone analysis of the
retrieved calculus.
Immediate Treatment
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ Significant obstruction§ Progressive deterioration of the kidney§ Irreversible infection of the kidney
(Refractory pyelonephritis)§ Unremitting pain§ Stone obstruction an infected kidney
Conservative Treatment
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ Antibiotic to control infection.§ Analgesics to give relief from
the pain§ Alpha blockers to dilate the
ureters [Tamsulosin] § Oral Hydrotherapy.§ IV fluids if there is nausea /
Vomiting
Treatment Options
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ ESWL (Lithotripsy)§ Ureteroscopy (URS) § Percutaneous
Nephrolithotomy (PCNL) § Open surgery
ESWL
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ ESWL in 1980 Chaussy in Germany § ComfortabLe for stones between 1.5
to 2 cm both renal & upper ureteric§ Might require DJ stenting for larger
stones§ Good diuresis is require post
treatment
PCNL
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ PCNL started in 1976 and used for stones larger than 2 cm
§ After placing a open ended catheter the collecting system is punctured and guide wire is placed
§ The tract is dilated & scope is passed to break and remove the stone
§ Good diuresis is require post treatment
Open Surgeries
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ Open renal surgeries are also difficult in rural areas
§ First pyelolithotomy was by Heinecke in 1879
§ Gil-Vernet in 1965 popularized modern surgery
§ We use URS & Cystoscope for stone clearance
Small Stones
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ Up to 5 mm pass within two weeks [71 to 98%]
§ Medical Expulsion Therapy for stones up to 7 mm
§ 7 to 12 mm DJ stenting could be tried if MET not sucessful
§ We use URS lithotripsy after 6 weeks with DJ stent
Medium Sized Stones
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ DJ stenting & wait for 6 weeks§ The Ureter dilates, inflammation
fixes Urothelium, less infection & improved renal function
§ URS & Lithotripsy after 6 weeks§ We use URS lithotripsy after 6
weeks with DJ stent
Large Sized Stones
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ We prefer removal using URS and DJ stenting with several sittings
§ Centers that have the facility would prefer PCNL with multiple punctures if necessary
§ We do open surgeries if facilities are available and prefer using Cystoscope or URS for stone clearance
The URS technique
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: URINARY TRACT STONES
§ Prior DJ stenting 6 weeks earlier § Pass guide wire and then remove DJ
stent§ Use Lithoclast to break the stones
into fragments§ Head down / tilt, etc are necessary
for visualizing the stone§ Flushing and alternating with suction
helps
The Prophylactic Antibiotics
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: DJ STENTING
§ The Aminoglycosides [Gentamicin / Amikacin]
§ The Cephalosporins [Ceftriaxone]§ The fluoroquinolones
[Ciprofloxacillin]
Post Operative Instructions
RURAL UROLOGYRURAL UROLOGY
RURAL UROLOGY: DJ STENTING
§ Sufficient water to pass 3.5 liters of urine a day
§ Usually the stents are removed in 6 weeks but should not have more than 3 months.
§ Reflux of urine might cause some discomfort
§ There might be pain while stone pieces come down
§ Less water would cause encrustations