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Beneficial Effects of Very LQW Dose Aspirin GilIcs illottttrlcst*ot. Jacrprcs Maclouf, Gkrard ktbitd’i, .io.sqiir .~dk071r17, Yws

Grosgqgeat, Dat7iel Ti7omas

Comparison of the d Aspirin Versus Aspirin Alone on Transient In-Hospital Progno Diana Holdtigi7 t, Devct 1 Tfiot77as, William Hubbard, Gordott Ifettdty, Gco~ge Sutton, Kbn Fox

Directional Corcnslry Atherectomy in Unstable Angina Akua E. Abdelme~#d, S~ep~7ett G‘. Ellis, S/7& K. Supp, Cot7rad Sin7pfendorfer, Iwitg France, Patrick L. Whitlow

Dose Finding With a Novel Recombinant Plasminogen Activater (BM 06.022) in Patients With Acute MyocardiPJ Infarction: Results of the German Recombinant Plasminogen Activator Study Karl-Ludwig Neuhaus, Rainer van Esset7, Albrechr Vogt, Ubich Tebbe, J@ Rus@e, Hans-Joacl7in7 Wagner, Karl-Ttiedrick Appel, Ubic:7 Stienen, Reinhard K&zig, Wo&atg Meyer-Sabeiiek

Relation Behveen Myocardial Infarct Location and Stroke Mot7ry M. Bodenlteimer, Deborah Sauer, Babar Shnreej Mats W Brown, JosepI L. Fleiss, Artl7urJ. Moss

Effects of Captopril Therapy on Endogenous Fibrinolysis in Men With Recent, Uncomplicated Myocardial Infarction Robert A. Wrigl7r, Andrew D. Flapan, K George M. M. Alberti, Cl7risropher A. Ludlam, Keith A. A. Fox

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At7dt~‘j S. Kosit7ski, Johrz S. Douglas, Jr.. Het7ty A. LibetTt7at7, D07@as C. MO& Spct7cer B. Kit7g III

Pu!mooary ~~e~~~~r~a~e After ~~t~~co~o~~~y Stent rzdm~ 1. h’acismc. Eric J. Top01

ridamole Eetlocar~~o~ra

Liri,i Soyetite, Paolo Rizotr

racic Two-Dimensional an Echocardio~~~l~~y Ifarlat7 M. K~zat7/7olz, Pamela S. Lee Guldtt7at7, Cam! Waksmot7ski

EART FAILURE Prognostic Value of oppler Transmitral Flow Patterns in Patients With Congestive Gotrg-Yuatt Xie, Martit R. Berk, Mike1 D. Stnitlt, Jo1717 C’. Gurley, Andtony N. DeMatia

Myocyte Nuclear and Possible Cellular Hyperplasia Contribute to Ventricular Remodeling in the Hypertropbic Senescent Heart in Humans Giotgio Olivetti, Massimo Me/i.s.vari, Tiziat7a Balbi, Federico Quait7i, Edmund H. Sot7nenbiick, Pier0 At7vcrsa

Editoriaf Comment Adult Myocyte Wyperplasia: Divided They Fail? Marc A. Pfefet; Jat,ice M. Pfefir

the Transmitral Gradient in Patients With Mitral Stenosis: A Simultaneous ~at~~ete~~~~~tioa and Doppler Ecbocardiograpbic Study Rick A. Nishimura. Charatljit S. Rihal, A. Jamil Tajik David R. Ifobt76 Jr.

Left Atrial Appendage Function and Thrombus Formation in Atrial Fibrillation-Flutter: A Transesophageal Ecbocardiograpbic Study Derek Santiago, Ma4 Warshofikv,

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Gillsepp Li Mandti, Marco Di T&o, James Coromilas, James Reifel, Shunichi iiomma

Left hiarial Fan&ion aad Vent&alar Filling io Hypertensive ~aroxysaml Atria1 Flbrillatioo Paolo Barbier,

i&o, Maurizio D. Guz~i

oaophasic Waveforms in David Keane, Edward Boyd,

Philip Deverall, Richard Monk, Graham k&on, Edgar Sowton

Asymmety of Retrograde Coaduction and Reentry Within the His-Parkiqje System: A Comparative Analysis of Left and Right Veatricalar Stimalation Ali Akbar Mehdirad, Stephen Keim, Kevin ffist, Todor Maqaltv, Pahick Tchou

I Conduction After Orthotopic Heart Transplantation nselme, Nadir Saoudi, Michel Redonnet, Brice Letac

PEDU~C C&RDIOLoGY of Pregaaacy After the Mustard Operation for

sitioa of the Great Arteries With Intact Ventricular Patricia M. Cl&son, Nigd J. Wihn, John M. Neu~ze,

Ro@a A. Notth, A, Louise Culdcc Btian G. Bamrft-Bojvs

Persistcat Hyperdyaamic Cardiovasculur State at Rest sad xercise in Children After Successful Repair UP

tioa of the Aorta Thomas R Kimball, John M. Wayne A. Mays, Philip Khoury, Rattdal P. Cluyror,

Stephen R. Danialv

IoPuLMoNmY RESUSCITATION Active Compress&a-Decompression Resuscitation: E&cl on Resuscitetioa Success After In-Hospital Cardiac Arrest Kelly J. Tucker, Frank Galli Michael A. Savitt, Daniel Kahsai, Lalrm B~snahan, Rita F. Red&q

RIhrllENTAL STUDIES 267 Death of a Friend: “1 Want to Die!” IWkm W. Pam&

Abnormalities in Sympnthoaeuronal Regulation Arc Localized to Myocardium in Rabbit Weart Tsuromu Yoshikawa,

Shunnosuke Handa, Masahim Suzuki, Keiichi Naganri

A New Approach for the Qaaatificatioa of Complex Lesion Morphology: The Gradient Field Transforat; Basic Principles aad Vnlidatloa Results Pieler M. J. CWA der &t, Johun H. C Rder

ACC NEWS 269

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President’s Page: Politics and Preventive Care Daniel J. Ul!so~

LETTERS To THE EDITOR

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Effects of Long-Term Right Ventricular Apical Pacing on Left Ventricular Perfusion, Innervation, Function sad Histology Michael A. Lee, Michael WI Dae, Jonathan J. Langberg, Jeny C. Gtijin, Michael C. Chin, N’alter E. Finkbeiner, J. William O’Connell, Elias Botvinick, Melvin M. Scheinman, M&ten Rosetqvist

Inherited Ventricular hbythmias and Sudden Deatb in Germao Shepherd Dogs N. Sydney Moise, vi& Meyers-Wallen, William J. Flahivc, Bed1 A. Valentine, Janet M. Scarlett, &&a A. Brown, Marrlew J. Chavkin, Dee A. Dugger, Shati Renaud-Farrell, Bruce Kornreich. William C. Schcenbom, Jennifer R. Sparks, Rob& F. GilmouK Jr.

Editorial Commenl Puppies’ Programmed Sudden QeatR: Ils the Serial Killer? Philippe Coltme/, He& Le Marec

Iatracordiee Ultra iaation of Veatricular Volumes: In Vitro ~~~~~U~O~ ltt $. Fisher, Cam’e A. Woljlq, Juseph S. Mikatt, Francis J. Kiernan, Daniel B. Fram, Raymond G. McKay, Linda D. Gillam

Quaatillcation of Pericardial Elfusioas by Tbrec-Dimcasio~al Ech~o~i~~pby Jose A. Vaquez de P&a, Letrg Jiatlg, Mark D. Hanrlsc~~~~m~~c~ier, Soltg Wei Xie, J. M@el Rir rra, Wud Scltwan~nrerill~crl, J. Ltris Guen-eta Arthur E. Weymutr, Robol A. Levine, Michael H Picard

REVIEW ARTICLE

Current Status of Myocardial Perfusion Imaging After Percutaneous Traasluminal Coronary ~gioplasty D. Doug/as Milk, Mario S. Vcrani

AUGUST 1994 VOLUME 24 NUMBER 2

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BETHESDA CONFERENCE REPORT

t5tb Betbda Conference: Fature Personnel Needs for Cardiovascalar Health Care Rolf M. Gunnar, Conference Co-Chairman, Roberta G. Williams, Conference Co-Chairman

343

CLINICAL STUDIES

Abmmd Cardiac Pain Perception in Syodrome X Anoop Chuuhan, Paul A. Mu&u, &in i. Thuraisingham. Gem& Tityl~, Michael C. Pet& Peter M. Schofield

Intie of Residaal Perfasioa Within the Infarct Zone on the Nataral History of Left Ventricular Dyslimctioo After Acute Myoawdial Intarctioa: A Myocardial Contrast Echocardiogntphic Study Luciano Agati, Paolo V&i, Federico

354

Bilotta, Roberlo Luongo, Camille Autore. Maria Pence, Carlo Iacoboni, Francesco Fedele, Annando Dagianti

Assessment of Viable Myocardium by bbatamiae Transesophageal Echocardiography and Comparison With Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography Frank M. Baer, Eberhard Vol Hails J. Derttsch, Christian A. Schneider, Hamld Schicha, Udo Sechtem

CORONARY Ammy DKXA~E Prognostic Significance of Cardiac Ciaelluomscopy for Coronary Calcific Deposits in Asymptomatic High Risk Subjects Robert C. Detmno, Nathan D. Wang, We&i Tang, wiliam J. French, Demetrios Georg’ou, Eda) Ygnng, 0leh S. Brezden, Terence M. Lkderty, Kenneth A. Narahara, Bruce H. Brundage

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artz

Kasper, Elisabeth Kauder, Annette Geibel, Mat&n Schtittdtaler, P~ai~~ed ~~sc~aet*~ki, Hattj@ Jlfst

g I &tccessft.tl

ze, Kaztdtiko .%hida, Masaslti Naka, Jttrt Tamai, Masaaki Uematstr, Ytrkihiro Koretsune, Shinsttke Nanto, Masatsugu Hori, Michitoski lnoue, Takenobu Kantada, Kazuhisa Kodama

sican: Clinicnl Study S/llor,ti Mate&@, Gabriel I. Barabash, Atttir Shahar, Babcrh Rabinowitz, Sit~ttttel Ruth, Yedael klar Zahav, &en Agrartat. Elieser Kapli~sky, Narrocit Hod

Extent eso~~tt~~: A Simple but &rung fieats With Acute ~yoco~~~a~ infarct Di.ssmann, Thomas Briiggetttann, Karl Wegscitcidet; Thomus Linderer, Ulrich T&be, Karl-Ludwig Neirhaus

Recovery of Atriai Function mer Aerial Com~a~ment Operation for Chronic Atrial Fibrillation in Mitral Valve

isease Kou-Gi Shyu, Jtot-Juck Cheng, Jin-Jer Chen, Jiann-Li Lit, Fang-Ytie Lin, Yung-Zu Tseng, Peiliang Kuan. Wen-Pin Lien

influence of Reversible §e~me~tat Left Ve tricdar DysfMunction on Heart Period Variability b Patients With One-Vessel Coronary Artery Disease Domenico Eonaduce, Mario Petretta. Fedetico Piscionc, Ciro btdolji, Marie Louise Migaux, Valter Bianchi, Nicola Esposito, Fortunate Marciano, Massimo Chiarieflo

preliminary Experience With a Hybrid ~o~thoracotomy Defibrillating System That Includes a Bipbasic Device: Comparison With a Standard Monopbasic Device ‘Using tbe Same Lead System Andrea Natal, Jasbir Sra, Kathi Axtell, Cheryl Maglio, Anwer Dhala, Sanjay Deshpande, Mohammad Jazayeti, Abdul Wase, Masood Akhtat

Ediroriof Comment A Food and Drug Administration Request for Cooperation Jefiey D. Jones, Thomas J. Callahan, Susan Alpert, Murk Barnett

Editarial Comtttett~ The Art and Science of Mixing and Matching James D. Maloney, Dirar S. Khoury, Weiri Zhu, Carlos Rizo-Patron

Underdetection of Ventricular Tacbycardia by Algorithms to Enhance Specificity in a Tiered-Therapy Cardioverter-Defibrillator Charles D. Swerdfow, 77totttas Ahent, Fevtg-Shcng Chett, Clmtt Swung, Eli Gattg, Ii’t2iarn Mandel, Rebert M. Kass, C. Thomas Peter

Coronary Angioplasty Versus Bypass Surgery in Patients >70 Years Old Matched for Ventricular Function James H. O’Keefe, Jr., Matthew 8. Sutton, Ben D. McCallister, James L. Vacek, Jefiey M. Piehler, Robert W L&on, Geo&y 0. Hartzler

Randomized Trials of Directional Coronary Atherectomy: Implications for Clinical Practice and Future Investigation David R. Holmes, Jr., Eric J. Topoi, Allan G. Adelman, Eric A. Cohen, Robert M. Calif

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nt Flow V&me Based on C

Holcomb, David J, Sahn

plep Color Flew Study

A. Vazquez de Pradu, At&u E. Weymun, Rober/ A. Levine

c Changes og Ort tic upitIe nryap sictn

Scitutzman, Fredtick Jaeger; Jumes Malone?; Fetnat Fouad- Tarazi

Fuwctioll After Recovery From Acute Dilated Cardiomyopathy Marc J. Semigran, Cynthia M. Thaik, Michael A. Fij>r, Char/es A. Botrcher, igor F. Palacios, G. William Dee

AGING

S. Kc/d E. Geot~akopoulos, Jacqui Robinson, John E. Deanfield

Substance P Potentiates the Algogenic Effects of ~~t~~a~e~ia~ lafusion of Adenosine Achilie Caspardone, Filippo Crea, Fabrizio Toma!, Malia latttele, Duvid C. Crossman, Marco Pappagallo, Francesco Versaci, Luigi Chiariello, Pier A. Giofi>

EDtAT ~R~t~~~~~ Right Ventricular Outflow Reconstruction Homogra~ts in Fe~iatr~c Patients: tnterme~iate-Ter~n FoBlow-Up With Serial Ecbocardiogra~bic Assessment kszok C‘hirr C/tail. Derek A. Fyfe, Christine A. McKay, Roben M. Sadc. Fred A. Crawford

Use of Sertraline Hydrochloride in the Treatment of Refractory Neurocardiogenic Syncope in Children and Adolescents Blair P. Gnrbb. Danicla Samoil, Daniel Uosinski, Katrinka Kip. Pamela Brewster

NEW Bntrav sound Umaging in Acute Aortic Dissection Andrew R. Weintraub, Raimund Erbel, Giinter Giirge, Steven L. Scitwartr, Junbo Ge, Thomas Gerber, Jiitgett Meyer, Tsui-Lieh Hsu, Robert Bojar, Sabino Ilicero, L. Carella, Pa010 Rizzorr, Isidre Vilacosta, Jalier Goic*o/etr. .JOSC~ Zmwmw. Fernando Alfortso, Natesa 6. Pandiart

Three-Dimensional Echocardiography: In Vitro and In Vivo Validation of Left Ventricular Mass and Comparison With Conventional Echocardiographic Methods Aasha 5. Gopal, Attdrew M. Keller, Zhanqing Shen, Peter M. Sapin. Klaus M. Schroeder, Donald L. King, Jr.. Donald L. King

Editorial Comment Heart Size: One-, T~Q- and HOW

Three-Dimensional Echocardiography Geese A. Mensa/t, Benjamin F. Byrd 111

Analysis of Transmural Tre of Myoedrdiat Integrated Ultrasound Backscatter for lfereotiation of ~~yt~e~tr~~~~tc Cardiomyopathy and Ventricular Hypertrophy Due to Hypertension Johji Naito, Tohrzr Manryanta, Jart Tar~uc~hi, Toshiaki Mano, Hiroya Uondo, Kaztthiro Yamamoro, Reiko Nagano, Masatsugu Hori, Michitoshi Inoue, Takenobu Kamada

555

525 Polymeric Stenting in the Porcine Coronary Artery Model: Differential Outcome of Exogenous Fibrin Sleeves Versus Polyurethane-Coated Stents David R. iioimes, Jr., Ah R. Camrtd, Michael A. Jorgenson, William D. Edwards, Roberr S. Schwaartz 567

532 Two-Dimensional Mitral Flow Velocity Prufiles in Pig Models Using Epicardial Doppler i%hocardiography cf yu~rg Kir,~, l%rrr Bisgaard, Sten L. Nielsen, Jens K. Paulsen, Erik M. Pedersen, J. Michael Hasenkam, Ajit P. Yoganathan

569 ARTICLES

571 546 Pmssive Smoking as a Cause of Heart Disease

A. Jd.su/t Wdh 578

Nitric Oxide alad ~itrQvasu Potential Interactions Todd 9. A&~ISOIF, Iun T. ~~re~~~~~, Peter Ganz, Andrew P. Selwyn, Alan C. Yeung

Practice Guidelines and Coo CoOkS? WiNiflrn W. Parnd~

e

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tion in Patients With

6.36 Chantpluin, Daniel Bichet, Marc Klein. Jacques R. Ro~leau~ Brua* Sussex. J. Malcolm An&l, Fruncois &tier, John 0. Parker, Patricia M&wan, Victoria Bernstein. T Edward Cud&, Gcnvtsio Lamas, Stephen S. Gottlicb. John McCuns, Clantic Nudeau, Fran~ois Dela,ce, Chuan-Cl.~i C. Wun. Marc A. t$$r

Clinical and Biibemical Facturs Assuciuted With Prognosis Alter Myucardial Infarction at a Yuung Age Kl1rs lvhlbq, Pm‘ lIlhldlollrr. hkm Iim~l.st~‘~r

A Simple ~l~t~~~i~~apbi~ predictur of the Outrwme of Patients With Acute ~ly~ardi~~ In~~~ti~)n Treated With a

AG Italian0 per lo Studiu delh nfart urdicu ((;tSSl=2)-~~v~

i+uiicewco ~f~irrri, Alib Pima Mli@rli. Mwia Chcicr

C.%lrlc/io De C&a, El~qtvib Su~rl~krm Luigi .%mtfnv, Pantuleo Giunnrr::i, Gianni Tognoni fijr the G!SSI-.Z in~vsti~uton

b49

655

rs ul Nonfatal Reinfarctiun in Survivurs uf Myocardial II After Thwmhulysis: Results of the Gruppo Italianu

per lo Studio della Sopravvivenza nell’lnfarto Miocardico ta Rasp clcl Hoc Working Gmup af GISSI-,$ Duta

&se: A/bertv Vblpi, Uarrdio De &ta, Maria Gnciu Frarr:osi. Ewi~ Gmci, AidId> Fit~m Mt@orri, FWitc*~~st*~) Mawi. Ew Nqri, Etrgerio Smttom, l&i Tin-axi. Gianni figioni

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Ho+, Kent R. Baili?

YoCARDtAL ISCHEMlA Stress Ecbocardiugraphy Predicts Reversible

bsfhction and Quantitates the Extent of Irreversibly Damaged Myocardium After Reperfosion of Ante&r Myucardial Mmtion Himtaka Wbtada, Hiroshi Ito, Hidenrasa Oh, Tohnc Mw)‘al?lu. Masahito Ahmmya, Masatsigr Hori_ Masaorni hklrm. Yorihiko Higashino, Kenshi Fxjii, Takazo Minamino

676

V~nt~ic~~ar Wall Motiun A~no~~~aiities in SMb~racb

Collagen Application Versus Manual Compression: A Prospective ~audomix~ Trial fur Arterial Puncture Site Closure ARer Corunary Angioplasly Edoardo Cantc~n:ind. Mariamre Gmssliol:, fJhilt$ Urban. Pi4 I s ?whlrC; Dorsuz D~nninique Did& Bernhard M&r

KAliT‘ iLURE ntracavitary Filling Pattern in the Failing Left Ventricle

Assessed by Culor M-Mode Doppler Ecbucardiugraphy Mwic Strtgxd, Ctr ilit- Risiie. Ha&fan lhlcn, Otto A. !imi.seth

Incidence of Pulmunary Vein Complications After Lung Transplantation: A Prospective Transesupbageal Echocardiugrapbic Study DutU It! Leibowitz, Cmig R. Smith, Robert E hfichler, Mark Ginsbrag Lab!-rcncc L. Sclurhnan, Carlton C. McGregat. Giuseppe Li Mandti, Rence G. Weslow. Marco R. Di T&o, Shunichi Hommu

Hancock II Porcine Bioprusthesis: Excellent Durability at Intermediate-l’erm Follow-Up Uberto Burtolotti, Aldo Miluno, En:o Mazzaro, Gaetano Tlti~w, Ewico Talemi. Dirro Casaruttu

OCTOBER 1994 VOLUME 24 NUMBER 4

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2t&& ~ptbesda Conference: Recommendations for Determining Eliibility for Competition in Atbletes With CardiOVaWdar

Abmmtitis Bury .f. Maron, C5t&me Co-ChuintIapt, Jere ff. Mitchell Conference Co-Chaimtan

Oelineation of Exteuded laengtbs of Coronary Arteries by Multiplane Tran~sopha~eal ~~h~ardi~~~hy JeatKlrrude Turd% Mani A. Vattttu9r, Ketuirth Taylur, Steven I.. .!!chrvitrt.z. Nutw 6. I’mdun

Wow Accurate Is Dobutamine Stress Electrocardiography for Detection of Coronary Artery Disease? Comparison With Two- Dimensional Ecbocardiograpby nad Technetium4Hm Metboxyl Isobutyl Isonitrile (Mibi) Perfusion Sciatigrapby Geqes H. Mairesse, 7ltomas H. Matwick, Jean- Louis J. Vanovetwhelde, Thieny Barrdhuin, Willium Wijns, Jacques A. Me&t. Jeun-Marie R. Detty

False Positive Dobutamine Stress Echocardiograms: Characterization of Clinical, Ecbocardiograpbic and Angiographic Findings David S. Bach, David W. M. Mdkr. Bernunl J. G9w. Wilhatn F, Atwtstrott~

Dobutamine Stress Fkzbocardiography: Detection of Cranny Artery Disease in Patients With Dilated Cardio /%!a S&p, Stepherr G. Suwada, Dorrglas S. Segar; Tlr Rmuttte Kovacs. Naomi S. Finebetg Harvey Feigenbaum

Guide Wire Venus Stress Single- rapbic Thalliua-201 Imaging e

Assessment of Intermediate Coronary Stenoses James D. Joye, Dot@as S. Schidman, David Lusorda. Tot~y Fat&, &yutt C, Dwtohuc Nuthmiel Reichek

d I.-Arginine on A~~lcholin~Iudu~ Endotbelium- Dependent Vasodilation Differs Between the Coronary and Forearm Vaseulatures in IIunans Yoshitaku Himoka. Kensuke &ushim, Twt~tntr Itnaizwni, Tatsrya Tugawa. Hisashi Ku. Masam Stt~zitnachi, Akim Takeshita

of Autonomic Nervous System Dysfunction on the ian Pattern of Myocardial Iscbemia in Diabetes Mellitus

Strrirfl Zurich. Seqio Mr,,,tatt, R(ay T. Freetttatt, Mwray Minletttatt, Patriciu Htxur& Richard W. Nestu

Timing of Sudden Death in Patients With Heart Failure Debra K Mosec &?lliam G. Stesenson, Maty A. Wm, Lynne iK Stevenson

~t&ia~ Cotnmeti Triggers and Timing of Coronary Events and Sudden Cardiac Deatb Pmkash C. Deedwania

912 Evidence of cart

LaManca, Satlford Levine

~em~ynamic E&cte of I~ba~~ Nit& Marc J. Semigmtt, Ba9inwa A. Cock93 R Thomnpsatt, Watwt M. Zapoi, G. ~~~lia~t Dee, Michael A. Fifrr

Segovia, Maria J, Pew- C’ixayt~o, Catnitto Batiuelos. Joao C. S&a, P&t Zarco* hiir!os Macaya

An~~o~lasty Louis I. ~~t~~~~~~. Ke(ctt H. Silt-w. s, Shamtt J. Bulcortr. Burrrtic H. Weiner

Clubal Left VenU~~nlar ienq Virns infection etro 6~6, Duttieaico

Cationi, Paula Satttopudre, I/ii)tcettzo Vtrllo, Augasto Cire/i, Gioaio Mighatr

8x31 inaction Witb ion in Late-S iom Wits

Ahvie Herskowitz Ti~y-C~~m~c Ith, Shmtt B. Wiliough!y, David vlaho~; Afiab A. Attsati, Willatn E. Besehorne& Kettncth L. Ba~t~tt9ttatt

iow Frequency of Detection by Nested Polymerase Chain Reaction of Enter&-us Rlbonncleic Acid in Endomyocardial

tients With Idiopathic Dilated Cardiomyopathy Maw Giacca, Giowttni Maria Severini, Luisa Mestrotti. Alessandro Sahi, Gemrdina Lardieri, Armro Faluschi, Ftdvio Canterini

A Simplified Method for Determining Regurgitant Fraction by Doppler Echocardiography in Patients With Aortic Regurgitation Gang-Yuan Xie, Maflin R. Berk, Mike1 D. Smith, Aathotty N. DeMaria

Vnsodilator Therapy in Chronic Asymptomat~~ Aortic Regurgitation: Enalapril Versus Hydralazine Therapy Mike Lin, Hung-T@ Chiatg Shea-Lin Lin, Mau-Song Chartg, Betqa9nin N. Chiang Hsietr- Wen Uu5, Melvin D. Cheidin

LEFT VENTRICULAR FUNCTION Comparison of Two and Three-Dimensional Echocardiography Witb Cineventrlculograpby for Measurement of Left Ventricular Volume in Patients Peter M. Sapin, Klaus M. Schriider, Aasha S. Gopat Mike1 D. Smith, Anthony N. DeMatia, Donald L. King

istic ActioII of severe

c

erties Lloyd M. t%l’iS, H. Lee Kmtter, Eric C. &yet+, Je@q E. Sa,@z

Outcome at 1 Year Jffrl wf der A4eer, Ant? Brtrrel de kr RiriZre,

Wiek H. mutt Gilst. Harts L. Hilkege. hkrttltius l’jstere); Gcwit J.

Kootstra, Peter H. J. M. Dtrttselmus Bw/xtrrr J. hf. Mulder, Kong 1.

Lie, for tlte CA BADAS Rcseurcit Group of the Itttertrni~~ersi~

Cardiology lttstilrrte of Tt't e Ne~Iwrkrntls

immediately After Coronary Artery Bypass Surgery AIrice A.

McKennq Carl S. Apstein, Lisu A. Mendes, Gilbert P. Connellv,

Gabriel S. Aldea, Richard J. Slremin. Ruvitr DovidojT

Outcome of Percutaneous ~ra~s~~rni~a$ Coro Subsets of Unstable Angina Pectoris: A Report of the 19SS-~98~ National Heart, Lung, and Blood Institute Pe~cutaaeoas Transluminal Coronary Angioplasty Registry Lumber70 G. Benrivoglio, Kat!terine Detre, Wanlin Ye/l, David 0. U?f!iuttts,

Sltetyi F. Kelsey, David P. Faxon

Long-Term Angie ic sad Ci~~ical Outcome ~rnp~a~~~tio~ of a o~-~x~a~n~a~~e Stent in the Native Coronary Circklla Miclluel P. &wage, Dulu L. Fiscltman,

Rickurd A. S&z, Puul S. Teirxtein, h4artitt B. Leon, Donald

Buitn. Step/ten 6. Ellis, Eric J. Topol, Jo/m U! Hirsltfeld. Micituel

WI C~etnutt, h4artrice Bnclthinder. Steven guile!; Ricltard Heuso;

Craig M. Wulkcr, R. Clwrlev i’lrny Jr., Slwon Gel)ltardt, Rattdui

Ruke, Siteidott Goldberg, for the PldtnasSchut: Sfertr Stfrtly Gr01tp

Editorial Cotnment Stents: A Time for Clinical ~~dgmeRt Jo/m 61. K. Vogel

Glazier: V~~llappiilil Gmtgadlturatt, Dominic L. Marsulese, Tlwtirtre

L. Schruih; Wiliium W. O’Neill

nitial Clinical Experiewes Witb Rescue Unipolar Rad~ofre~ue~cy Thermal Balloon Ang~o~~asty After Abrupt or Threatened Vessel Closure Compiicatirag Elective ConventiQnal Balloon Coronary Angioplasty S@eru Saito, Hideknnr Anti,

Kunikatte Kim, Naoto Aoki

1229 Long-Term Mistologic Patency After Percutaneous Transluminal Coronq Angioplasty Is predicted by the Creation of a Greater Lumen Area Andrew Fati, Renu Vimani, James I3 Atkinson, Peter G. Andemn

1m &&th&bl in Fatieats With Coronq Heart Disease Undergoing Cardiac Catheterization Giks Monlahco!, Isa/&/e fios.wt, pierrp E. Chabrier, Ivan Sokov, Jeun P. 1X~ienne, Gi& &&ski, Roberz Frank, YC’L’S Gt-osgogeat, Datziei Thomas

/-&vaE hh.9CAWMA& bM.R~ION tm NW Recombinant Glycosylated Prourokinase for Treatment OF

P-atieats With Acute Myocwdial Infarction W. Do4&S Weaver, Joseph R. Hurfmantz, Je& L. Anderson, P. Szzdjzakap bzpddy. J&n C. Sobofski, Artlrur A. Sasahafa, fat the t3ozuokbzase S&y Group

1241 Cost-E&tiveness of P New Short&q Unit to “Me Out” Acute AQwatdiul Infarction in Low Wisk Patienk Jeatz-Michel Gasp, Thoyzzas H. Lee, Miltott C, Weimr~~in, E. Fratrci~ Cook, Paufa Gokdman, Anthy I,. Komczrofi Lee Gokiman

101 IkJbutamine Stress &hocardiogrrephy for at&eents With Coronery Artery Disease Jzdio A.

!+mrrr, Joy M, Lazrtietr~t, Rod@) I/. Czzti4 Atxhed A. Qzzyyzrtrzi, Rich& 0. ChtftM iI1

a%$ LelR Ventricular Vollsme Changes During ~bu~mi~e Stress ~~~~i~~~~y Identifj Patients With More Extesssive Coronary Artery Disease Clnarl~~s 6 Olsotz, Thotnas R. Porzer, Ubeydzr&zh Del,srrtrl, Fetzg Xie, Jatrtes R. A&eflort

1274 Limited Usehlness of Exercise Testing and Thallium Scintigraphy in Evaluation of Ambulatory Patients Several Months After Recovery From an Acute Coronary Event: Implications for Management OF Stable Cwonary Heart Disease Ronuki 9, Kroml, Johtz J, Gtqptj-, Ketztzedz E Freediancl R&rz

E, Kkigt~r, Fnztzs .I. Th. Wtzckers. Motzry M. &detzheimer, Jcsuia Benhoritz, Rotzald G. Schnw~, Johtt 0. Pzzrkcr. 1.zzqv Van VoorJ,,,:, Atfhzr r J. Mosx, fix rtzt* Mzr hicettrer rC@ocardial lsthemir r Rc~eu~lz Gtuzrp

1282 Best TechnetiunMm Sestamibl Tomography in Combination With ShortmTerm Ad~imist~t~on of Mtrates: Feasibility and WelirbPity for Predletion of Postrwnscularization adutcnme of Asynerglr Territories Giarztzi &i, Robetio Scia@z, Giovarrrzi A%: Smtm, &r Filipp Fuz.zi~~i

E

Westi Disease on Morbidity and r Extremity 8evasculari~tiom Surgery: A

tudy in Olmsted County, Mirnesotlt Michael 6 Ftzrkozih, CJzararzji~ S. RiIztri, &nzard

J. Gershl Thom W. Rooke, John W. Hallett, Jr.. W M&xi Q’Fa/totz, David J. Ballural

&ITLlZATION OF k0CEDUIRES 1297 Variation in Utilization of Cardiic Procedures in the

naent of Veterans Affdrs Health Care System: Effect of David M. Mhix Rohcrc 31ms, Army Gmch,

onrm Char. Mu&au Grmq

EART FAILURE 134@ E&ct of lbaetop~~l~l oa Myocardial Function and Energetics in

Patients with Nonischomic Dilated Cardiomyopathy A ~adomiaed, Double-Blind, Placebo-Controlled Study Efic J.

Eichhom, C’hristiatz M. Heesch, James H. Bamefr, LzaL 6. Alvarez, Steven M. Fass, Paul A. Grayburn, Barbara A. ~a~e~d~ Lucille 6. Marcou, Craig R. MnUoy

1321 E&ct of ~g~otens~n=Co~ve~i~~ Enzyme ~~b~bito~ 8811 Eadotbe~ium-~e~~de~t Peri~be~~ Vasodilatiora in With Chronic Henrt Failure nilotoyzzki Nakamzzm, Tsutvmu Fzmukvs/zi, Naoshi Arakawa, Hiroaki Yoshida, Shitzji Makira, Katszrhiko Hiramon’

1376 B&wing the Circulation: Theapwtic Optimization of PuimonarylSystemic Flow Ratio in Hypoplastic !L& ikwt Syndrome CBfr Bamca, Er3s H. Austin, Batftara Ric/zmaw, William P. Satzfanzore

138% Enharced Thrombolysis, Reduced Coronary &occlusion and Limitation of Infarct Size With Liposomal Prostaglandin E, in a Canine Thrombolysis Model Steve/t Fcld, Geoqe Li, Junm Amizian, Putty Fe& Wiant K. Vu~cghrr, Michel Accad, TIzaddezzs R. ToiIesott , Clztistine Swenson, Marc Ostro, Richard W Stzzallitzg

1391 Gatnma=Glutamylcysteine EtbyB Ester for in Dogs During ischemia and Iteperfusion Slriro &shida, Tszmehiko Kzz~zzya, Nobzzshige YumasIzira, Masaslti &&da, Shigehisa Kituhara, Masatszzgzd Hori, Takerzobu Kamada, Miclzihiko Tuda

1398 Morphologic Characteristics of Lesion Formation and Time Course of Smooth Muscle Cell Proliferation in a Porcine Proliferative lResteaosis Model Atzdrew J. Caner, John R. Laird, Andrew Fati, WXum Kufs, Dale C. Wortham, Renz; Urmatzi

t-4 15, 1994 E 24 6

Ihad, Jean Boiand, Mark A. Thompsort, Jaccps Mac/lecol4rt, A91tok9w tfv, George S. Pilcher; Cynthia A. Fink, Jefiey R. Burton, Maarlen L. Sinloons, RoIx~9~ M. Cd$ LX- ,1. Topol, A1lan M. Ross for the GUS TO

OlpiiS

With $t~e~t~~~~ase Marcc*llo Galvani, Duna R. Aberrdscheitr, Donatella Fenini, Fih@po Ottatri, France Rusricali, Paul R. Ei.tenbetg

Hein J. J. We/lens t t k Vermeer~ Chris de Zwaan,

chemia in Patients Circadian al) ./0/1tz E.

Deanfield, Jean-Mat+ R. 6. Deer), Paul R Lichden, Bnmo Magnani, ulow. fir fhe CAPE Shidy Group

n in the Systemic Arteries of Asymptomatic Subjects Relates to Coronary Risk Factors and Their Interaction David S. Celermajer, Keld E. Sorensen, Cathetine Bull, Jacqui Robinson, John E. Deanfield

NTERVENTIONAL CARDIOLOGY use of Balloon Catheters for Coronary giDph3ty: A tential Cost-Saving Strategy? Syfvain Plante, Bradley H. aws, Gilles Goulet, Randal K Watson, Robet? J. Chisholm

Editoriuf Comment Hs se af CorQa~~ Angiop~~s~ Cathethers Safe and E ive? Martial G. Bourassa

Thrombin Generation in Human Coronary Arteries Percutaneous Transluminal Balloon Angioplasty Jonathan D. Marmur, Piera A. Merlini, Samin K Sharma, Neda Khaghan, Sabino R. Tone, Douglas H. Israel, Diego Ardlssino, John A. Ambrose

ge to the Cardiac Stsuctwa sion hirrt S. Gottdienar, Bariv M. Mass& Aldo

Nocat@tcottro, Robe17 J. Hamburger, David W Williams, William G. HC~ldC~:W9, fur rite Depurtment of Vererans A,fairs Cooperali\~c~ .Fftrf@ Group on At1lilty~~~~r~~~fi.s~~~~~ .4genrs

Nishi Chatunsedi,

Petros Nihoyannopoulos 1 Michae! G. Marfttot.

Kreuzet orszewski, Ftiedetike van zur Miihlen, fieinrirh

Nabil El-Sherif

te Recovery After Exercise Is Accelerated in Athletes but Blunted in Patients Heart Failure Katsuji Imai, Hideyuki Sate, Masatsugu Hori, Hide0 Kusuoka, Hitoshi Ozaki, Hiroshi Yokoyama, Hit&i Takeda, Michitoshi Inoue, Takenobu Kamada

V. Schafi Thomas A. Orszulak, Michael D. McGoott, Bailq, Robert L. Ftye

Editaria1 Cammment Choosing the “Golden Valve Repair William J. Stewart

CARQIAC TMSPLAIVTATI~N Does Heart Transplantation Confer Additional Benefit Over Medical Therapy to. Patients Wbo Have Waited 24 Mouths for Heart Transplantation? Waiter Kao, Dan McGee, Y&an Liao+ Abin L. Hero& George M. Mullen, Mary1 R Johnson, Mati Rosa Costanzo

of Supine and Iatml RecumsWnt Positions on owy Venous Flow in Healthy Subjects Evaluated by

T-1 Doppler Echocardiography Kazuaki Tatlaix, Hiroyuki Yoshitomi, Nubuyuki Oyake, Toshihiko Asanuma, Tetwo Ohto, Yutaka M~ibashi, Tushio Shim&, Shigefimi Mk~ka,

Postope&ve Follow-Up of Fibromuscular Subao~ie Stenosis L4dpid M, Coleman, Je@ F. Smal/hom, Brian W. McCrindle~ GVilliam G, Wilftims, R&rt M. Freedom

Weinstein, Steven Leonard, W. Steves Ring, Hisashi Nikoidoh

High Intensity, Low Fr’eq~ek~q Dissolation of Occlusive @mm sod Ia Vivs Study Wolfsang Luo, Du-Yi Lee, Henry Nita, Da Tabak, Michelle Carborrne, Gerald Mare-er, Robert J. Siege!

of Dietary Suppleme&tatioon With ~pba-~~o~be~~~ um rdial !Marct Size and Ve

sion LiauwU Sebbag, R&i Fomt, Emmamrelle Cane& Se Retlaud, Jacques De/uye, Michel de Loqeiil

Cell Adhesion Molecules in CoPonary Artery Disease Yan~soo Jan& A. hfichaef Lincofi Edward F. Plow, Etic J. TopOr

Comparlscm of lFtxmt&oaded Recombinant Tissw-Qpe Plnsminoger Activator, Anistreplase aad Combination Tbrombolytic Therapy for Acute Myacardlrl Infarction: Results of the Thrombolysls in Myocardiol tnfarction (TN) 4 Trial Chrk~/~~r R Cunao~, GUU@ W, &N&+, Daniel J. Diver, Steve fferxtm, Robert RI, Greene, Brcninum K. Shah, Raphad kr: Sequebu, 1Cetdinand Leya, Jumes M. Kirshenbaum, Raymond 12 Magorien, S&astiun T. f%!mepi, ticki Davis, C. Michael Gibson, W. Kenneth Poole, Eugene Rmunwafd and the TfMf 4 hlvestigarors

ERY E or Anti&delnt Vita bw Density Lipoprotein tioa and impaired Endothelium-Dependent Vasodilation in

Patients With Hyperchoiestcrolemia David M Gi&an, Michuef N. Suck, Victor Guettu, Philip R. Casino, Arshed A. Qujyumi, Daniel J. Rader, J&o A. Panza, Richi& 0, Cannon ilf

I.+& Ventricuhr tarnine Stnsa

rly Diastolic Filling Dwiarg pby Is a Sensitive

iadiitnr Ij Sig&cant C~ronrry mery Disease Ef-Said M. El-Said, Jos R+ T. C. Roelandt, Yaofo M. Fioretti, Albert J. McNei& Emas For~rer, Hendrik Boersma, David i? Linker

Abnormal Coroarry Flow Qynamics at Rest and During Taebycardii Associated With Impaired I.& Ventricular Relaxation in Humans: Implication for Tachycardie-Induced Qocardirl lschemia Tohnr Masuyama% Masaaki Uematsu, Yasuji Doi. Kazuhiro Yamamofo, Toshiaki Mono, Johji Naito,

1633

1639

1645

1652

1669

1664

1672

Hiroy Kondo, Reiko Nagarto, ~fas~ts~~g~~ Hori, Takenobu Karnada

High Stress Regions io Saphenous Vein Bypass Graft Atherosclerotic Lesions Richard T. Lee, Howard M. Lorec, M&-hue 1 C. Fishbein

I lscbemia With Meatal Stress Testings Relation to the ggers of Ischemia During Daiiy Activities and to Ischemic Fuactioaal Severity John 5’. Guttdiena David S. Kmntz, Robert W. Howell, Gabrieia M. Hecht, Jacob Klein, Jenn$r J. Falconer, Alart Rozanski

tional Coronary Atherectomy 1s Required to Ensure Long-Term Angiographic Benefit: A !hdy With Matched Procedural Outcome Afkr Atherectomy aad Angioplasty Actor A. W. M. Umans, David Keane, David Fofqy, Eric Boersma, Rein Meikefi, Patrick W. Senuys

I%difying FluoroscOpy Views Reduces Opeprstor Radiation Exposure During Coronary Angioplasty Murk R. Pitney, Roger M. Allan, Robeti W G&s, Don McLean, Michael McCredie, Teprv Randeli, Wat7en F. Walsh

Expression of I&A=DR Antigen and Smooth Musclle Cell Differentiation Markers by Valvular Fibroblasts in Degenerative Aortic Stenosis Margaretu &son, M&en Rosenqvist, Jan Nilsson

Use of the Left Ventricular Peak Systolic Pressure/End-Systolic Volume Ratio to Predict Symptomatic Improvement With Valve

Kati~aritze A. Catartese, Howar~i R. Levitt

Hatter. Jacques ha. T. de Bakker, Corrw6i.s A. Grimbetgw Michiel J. Jieuc. Aretzd J. Dftrmitrg

~l~~ic~~ Anatomy af the Atriov Jo/m W. Dcatzv Sierz Yetz Ho, Nohr! *%J&WN!

732 Editorial Comnwn~ Anatomy of Atrioventr~c~~ar Attac ~o~~ect~a~s and ~~~ctio~: Itt Gerard AI. Guirarrdun

DIATRK IlOEQGY 1735 sk Factors for At&l ~~c~y~:r~yt

Operation Mark Gelatt, RCJ/JWI hf. Hamih, Briatt CC: McCrittdic, Roberr hf. Cow, William G. Williams, Grurg A. Tnrskcr, Robetf M. Freedom

Restenosis Hirojiri Saw, Craig Limdgret1, Burtott E. Sohel, Sutoslti Fujii

1810 Author Index: Volume 24

1814 Subject Pndex: Volume 24