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Science and community in the response to HIV, STIs and co ... · Community participation in each...

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www.iasociety.org Prioritization of expanding the free access to testing and treatment of HIV, STI, Hep C and other co- infections for MSM and other Key Populations, and the role of the community-based health service providers in such expansion (nothing about PrEP) Key words : Access, KP, Community involvement Praphan Phanuphak, MD, PhD The Thai Red Cross AIDS Research Centre Bangkok, Thailand, 17 November 2017 Science and community in the response to HIV, STIs and co-infections in Asia and the Pacific: Panel Discussion on PrEP & STIs
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Page 1: Science and community in the response to HIV, STIs and co ... · Community participation in each step of Reach-Recruit-Test-Treat-Prevent-Retain cascade REACH RECRUIT Refer to HIV

www.iasociety.org

Prioritization of expanding the free access to testing and treatment of HIV, STI, Hep C and other co-

infections for MSM and other Key Populations, and the role of the community-based health service providers in such expansion (nothing about PrEP)

Key words: Access, KP, Community involvement

Praphan Phanuphak, MD, PhD

The Thai Red Cross AIDS Research Centre

Bangkok, Thailand, 17 November 2017

Science and community in the response to HIV,

STIs and co-infections in Asia and the Pacific: Panel Discussion on PrEP & STIs

Page 2: Science and community in the response to HIV, STIs and co ... · Community participation in each step of Reach-Recruit-Test-Treat-Prevent-Retain cascade REACH RECRUIT Refer to HIV

www.iasociety.org

Access: to what services (testing,

treatment or prevention or all)?

• If resource is not a problem, it is cost-effective to have access to both treatment and prevention (PrEP) once you invest in testing.

• If resource is limited, one would invest in treatment, especially in early Rx which also needs early testing.

• Country has to prioritize.

• Certainly, if theses services are free, you will have more access.

Page 3: Science and community in the response to HIV, STIs and co ... · Community participation in each step of Reach-Recruit-Test-Treat-Prevent-Retain cascade REACH RECRUIT Refer to HIV

www.iasociety.org

Access to which population?

(General population or KP)

• Access to all population is ideal since KP is included.

• Access to all (general population) will minimize stigma and discrimination but it may not be cost-effective as compared to targeting at KPs.

• Message has to address general population but money and effort have to go to KPs.

Page 4: Science and community in the response to HIV, STIs and co ... · Community participation in each step of Reach-Recruit-Test-Treat-Prevent-Retain cascade REACH RECRUIT Refer to HIV

www.iasociety.org

How to meet the demand?

• Conventional health sector alone will not be able to meet the demand of the scaling up HIV services due to the limited manpower, service time and ability to reach the key populations.

• KP community organizations can help.

• It extends beyond community-based health services into community-led health services, called KP-led health services (KPLHS) based on the guiding principle of need-based and demand-driven

Page 5: Science and community in the response to HIV, STIs and co ... · Community participation in each step of Reach-Recruit-Test-Treat-Prevent-Retain cascade REACH RECRUIT Refer to HIV

Community participation in each step of Reach-

Recruit-Test-Treat-Prevent-Retain cascade

REACH

RECRUITRefer to HIV testing service, with referral letters, coupons, tickets and/or clinic registration support

REACHOnline or offline, to provide HIV education, promotional materials, condoms, lubricant, needles and syringes

REACH

RECRUIT

TESTBy health care professional team in a mobile clinic setting, along with referral to TREAT and PREVENT, may work with health care professional team to RETAIN

REACH

RECRUIT

TEST by KP lay providers

TREAT ART dispensing according to Differentiated Service Delivery model

PREVENT by PrEP/PEP

RETAIN in TEST, TREAT and PREVENT services

KEY POPULATION-LED HEALTH SERVICES

COMMUNITY-BASED HEALTH SERVICES

COMMUNITY OUTREACH AND RECRUITMENT

COMMUNITY OUTREACH

Page 6: Science and community in the response to HIV, STIs and co ... · Community participation in each step of Reach-Recruit-Test-Treat-Prevent-Retain cascade REACH RECRUIT Refer to HIV

Dusita Meekrua prepares to conduct a finger-prick test at the SWING drop-in center in Bangkok. “Every time I provide counseling service, I feel like I’m helping someone in my own family,” she says.

Source: FrontLines, March/April 2016, Dressed to Test: Empowered Communities Take HIV Services to the Streets

Key Populations-Led Health Services (KPLHS)

• “KP Community leadership”: services necessary for addressing the HIV epidemic and related health issues are identified by the community itself and are, therefore, needs-based, demand-driven, and client-centered.

• KP-CLHS is not just a service set up by CBOs but a true partnership between CBOs and government/public health facilities.

• Community health workers have their capacity intensively built and strengthened within a short period of time to provide “certain” health services with high quality.

• Counseling, finger-prick blood and oral fluid collection, test and report HIV test results, STI sampling, point-of-care CD4, TB screening

• PrEP and PEP

Page 7: Science and community in the response to HIV, STIs and co ... · Community participation in each step of Reach-Recruit-Test-Treat-Prevent-Retain cascade REACH RECRUIT Refer to HIV

Key Population-Led Test & Treat and PrEP services

CHIANG MAI

CAREMAT/MPLUS

Type of clients: MSM and TG

BANGKOK

RSAT

Type of clients: MSM and TG

SWING

Type of clients: MSWs

CHONBURI (PATTAYA)

SISTERS

Type of clients: TG/TG sex workers

SWING

Type of clients: MSWs

SONGKHLA (HAT YAI)

RSAT

Type of clients: MSM and TG

Page 8: Science and community in the response to HIV, STIs and co ... · Community participation in each step of Reach-Recruit-Test-Treat-Prevent-Retain cascade REACH RECRUIT Refer to HIV

KPLHS significantly contributes to national HIV

testing figures among MSM and TGW• More than 7,000 HIV testing and 600 PrEP services are provided to MSM and

TG in Thailand by community health workers in 2016

HOSPITALS

CBOs

CBOs

HOSPITALS

Page 9: Science and community in the response to HIV, STIs and co ... · Community participation in each step of Reach-Recruit-Test-Treat-Prevent-Retain cascade REACH RECRUIT Refer to HIV

Early diagnosis and early initiation of ART

can be achieved through KPLHS model

• Median CD4 count 366 cells/mm3 at diagnosis

• Median (IQR) time from HIV diagnosis to ART initiation = 15 (8-22) days

• Need close collaboration and mutual trust between CBO testing sites and

referral ART hospitals

Source: TRC Community-Led Test and Treat Study among Thai MSM and TG (Mar 2017)

Page 10: Science and community in the response to HIV, STIs and co ... · Community participation in each step of Reach-Recruit-Test-Treat-Prevent-Retain cascade REACH RECRUIT Refer to HIV

High risk individuals with high seroconversion

rate can be identified through KPLHS model

Thailand National AIDS Strategy to End AIDS by 2030 (launched in 2016)- Increase domestic funding to CBOs- Community-Led Health Services to be integrated as part of national health service system

Source: TRC Community-Led Test and Treat Study among Thai MSM and TG (Mar 2017)

Successfully engageat-risk individuals withhigh incidence of HIV

PrEP TARGETS

Page 11: Science and community in the response to HIV, STIs and co ... · Community participation in each step of Reach-Recruit-Test-Treat-Prevent-Retain cascade REACH RECRUIT Refer to HIV

Key Population-Led Same-Day PrEP Services

Behavioral questionnaire

HIV testing

Willing to take PrEP

Not willing to take PrEP

Blood collection for creatinine and HBV

antigen testing

Start ART immediately

Routine appointment

(at least 6-monthly HIV testing)

Risk assessment and PrEP counseling

process

More details on PrEP

Referral to renal doctor, consider re-screening for

PrEP, and at least 6-monthly HIV testing

CrCl >60 mL/min

Continue PrEP

Discontinue PrEP

CrCL <60 mL/min

Month 1, month 3 and quarterly follow

up

Provide a bottle of PrEP to start

Page 12: Science and community in the response to HIV, STIs and co ... · Community participation in each step of Reach-Recruit-Test-Treat-Prevent-Retain cascade REACH RECRUIT Refer to HIV

Jul 2011HPTN 052

96% prevention efficacy with

immediate ART

Dec 2012 The 1st Test &

Treat project in MSM and TGW in

4 provinces

Oct 2014 National Guidelines recommended ART regardless of CD4 count and PrEP

Nov 2010iPrEX showed

44% prevention efficacy among MSM with daily

TDF/FTC

Dec 2014 PrEP-30 at

TRCARC

May 2015 Community-Led

and Facility-Based Test &

Treat projects, along with PrEP

substudy in MSM and TGW

Jan 2016 Princess PrEP(KPLHS model)

Jan 2016PrEP@Piman

Mar 2016PrEP at SCC@Trop Med

Jan 2017PrEP2Start

Thailand’s PrEP programs

Oct 2018 Free PrEP for

high-risk MSM/TG

Page 13: Science and community in the response to HIV, STIs and co ... · Community participation in each step of Reach-Recruit-Test-Treat-Prevent-Retain cascade REACH RECRUIT Refer to HIV

Princess PrEP program: Key Population-Led PrEP Service Delivery Model

• Started in January 2016 aiming at providing

PrEP to 1,000 individuals at high risk for HIV

per year, through KPLHS

• More than 1/3 of PrEP users in Thailand have accessed PrEP through the Princess PrEP program

Page 14: Science and community in the response to HIV, STIs and co ... · Community participation in each step of Reach-Recruit-Test-Treat-Prevent-Retain cascade REACH RECRUIT Refer to HIV

Thailand’s PrEP programs

0

500

1000

1500

2000

2500

3000

3500

Dec 2014 Jun 2015 Dec 2015 Jun 2016 Dec 2016 Jun 2017

Cumulative number of PrEP users

PrEP-30 PrEP substudy Princess PrEP PrEP@Piman PrEP at SCC@TropMed Pulse Clinic MOPH PrEP2Start

Princess PrEP

PrEP-30

PrEP2Start

Page 15: Science and community in the response to HIV, STIs and co ... · Community participation in each step of Reach-Recruit-Test-Treat-Prevent-Retain cascade REACH RECRUIT Refer to HIV

Key Population-Led Health Services

(KPLHS)


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