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Smartphone-based Biomedical Human-Computer Interface
Spring 2011Daniel Shapiro; PhD Candidate
OCE Student Oral Presentation Competition
Biomedicine Problem
carg.site.uottawa.ca
DS: CARG 2011
Treatments for cognitive impairment:Drugs: side effects, Cost/Rx $37.44 [6],
2.8M people in Ontario’spublic drug system [5].
Surgery: only for extreme cases
Cognitive Behavioral Therapy: $40-180/hr [4]
Computer Assisted Cognitive Behavioral Therapy: Works!
In Search of a Solutions
carg.site.uottawa.ca
DS: CARG 2011
BrainPort, Tang et. al., lots of others…
Novel stimulus is the key: Works better than software-only approach. We opted to develop our own platform with smartphone integration.
Existing solutions focus on:•Aiding the blind, Sensory substitution, Lost balance
Electrode Array facing tongue = Novel Stimulus
NEAR Overview
carg.site.uottawa.ca
DS: CARG 2011
Inte
rnet
Industry Partner: NorDocs Technology Inc.
collaborative play, real-time image acquisition
4th prototype (32x32 array)
IntegratedDriver
Board and Electrode
Array
Sept 2011
What’s Happening?
carg.site.uottawa.ca
DS: CARG 2011
1st prototype (5x5 array)[2]
Sept 2010
3rd prototype (8x8 array)
Driver Board
April 2011
2nd prototype (8x8 array)
Driver Board
Jan 2011
carg.site.uottawa.ca
DS: CARG 2011
Value Proposition1. We estimate the accessible market opportunity in the
cognitive impairment market in Canada to be $1.75 bn/yr.
2. Estimated manufacturing cost of $100 per device
3. Existing solutions are not as flexible as an integrated platform
4. Cash raised = $350K + OCE matching • Currently TPS Lite, working on Collaborate application
and MITACS-accelerate
5. Projected revenue1. $1 million 20122. $3 million 20133. $10 million 2014
carg.site.uottawa.ca
DS: CARG 2011
Market Readiness 1.Provisional patents are in the works
2.R&D moving quickly towards 2011 human trials
3.FDA - Sec. 882.1320 Cutaneous electrode.Class II (performance standards). [7]510(k) application in 2012Health Canada application in 2011 [8]
4.Ethics application for trial in Ottawa on healthy subjects – Approval for Summer 2011fMRI and inpatient trials Jan 2012
carg.site.uottawa.ca
DS: CARG 2011
References1. M. Ptito, et al., “Cross-modal plasticity revealed by electrotactile stimulation
of the tongue in the congenitally blind”, Brain, vol. 128, no. 3, pp. 606-614, 2005
2. A. Borisenko, L. Monczak, I. S. Samra, O. Draghici, D. Shapiro, V. Groza, “A Low Cost Bidirectional Human-Computer Interface,” Medical Measurements and Applications (MeMeA), Apr. 2010.
3. H. Tang, D.J. Beebe, "An oral tactile interface for blind navigation," Neural Systems and Rehabilitation Engineering, IEEE Transactions on , vol.14, no.1, pp.116-123, March 2006.
4. http://www.camh.net/care_treatment/resources_clients_families_friends/challenges_and_choices/challenges_choices_abouttherapy.html
5. http://news.ontario.ca/mohltc/en/2010/04/expanding-access-to-affordable-drugs.html
6. http://www.theannals.com/cgi/content/abstract/36/9/13757. http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?
fr=882.13208. http://www.hc-sc.gc.ca/dhp-mps/md-im/applic-demande/guide-ld/
applabel_demmarque_priv-eng.php