Lastupdate:November2018
STEVENINVirginie(Ph.D.)11/19/1990Post-doctoralfellowattheLeidenUniversityMedicalCenterEDUCATION
2018:PhDthesisinMicrobiologyatthePasteurInstituteandUniversitySorbone-Paris-Cité.
2014:Master degree's 2nd year with Honors in Infectiology (Microbiology specialty). Pasteur Institute,DiderotUniversityandÉcoleNormaleSupérieureofCachan(France).
2012: Master degree's 1st year with Honors in Oncology. Paris Sud University and École NormaleSupérieureofCachan(France).
2011:Bachelor’sDegreeinBiology.ParisSudUniversityandÉcoleNormaleSupérieureofCachan(France).
2010-2014:Admission intotheBiologyDepartmentoftheEcoleNormaleSupérieure(ENS)ofCachan,aninstituteofhighereducationwithhighlyselectiveadmissionrequirements(20studentsselectedoutof800applicants,eachyear).
09/2008-09/2010: CPGE in Lycée Michel Montaigne, Bordeaux (France). 2-year intensive undergraduateprogrampreparingforthecompetitiveentranceexaminationstoFrenchtop-level"GrandesÉcoles".Major:Biology,Chemistry,Physics,andMathematics.
SCIENTIFICEXPERIENCES09/2014-09/2018:PhDthesis intheUnit“DynamicsofHost-PathogenInteractions”underthedirectionofJost Enninga at the Pasteur Institute, Paris. PhD project: “Investigation of the differential intracellularlocalizationofSalmonellaentericaanditsimpactduringtheinfection.”
12/2013-06/2014: 6 months internship in Infectiology in the Unit «Dynamics of Host-PathogenInteractions» under the direction of Jost Enninga at the Pasteur Institute, Paris. Entitled: “Intracellularbacterial localizationandhostresponsesduringbacterial infection: Impactof localcontextofthehostcellduringSalmonellainfection.”
11/2012-08/2013:10monthsinternship inMechanobiologyunderthedirectionofMichaelSheetzattheColumbiaUniversity,NewYork.Entitled:“Aroleforforminsinrigiditysensingofmotilecells.”
06/2011-08/2011: 3 months internship in Parasitology under the direction of Isabelle Tardieux at theCochin Institute, Paris (INSERM U1016 CNRS UMR 8104). Entitled: “Comparative analysis of fibroblastspermissivityforToxoplasmagondiibetweenWThostcellsandcellsoverexpressinganactivatedformofSrckinase.”
11/2010:ShorttrainingperiodintheCHIPIunitheadedbyDr.AlexandreBoissonnas(InsermU1135),Pierreand Marie Curie University, Paris (France). Entitled: “Modulation of leucocyte recruitment during anti-tumoralchemotherapy.”
TEACHINGACTIVITIES2018:SupervisionofaMaster1student(YoannLeToquin)for3monthsinternship.
2016:SupervisionofaMaster1student(JakubVoznica)for5monthsinternship.
09/2014-09/2017:Teaching responsibilitiesoncellbiology.64hof teachingperyears.DiderotUniversity,Paris(France).
[email protected]+33(0)6.85.49.01.64
Breestraat192311CGLeiden
TheNetherlands
Lastupdate:November2018
PUBLICATIONSHigh-throughputmicroscopicanalysisofSalmonellainvasionofhostcells.VoznicaJ,EnningaJ,StéveninV*-(*)correspondingauthor.BioProtoc.2018.doi:10.21769/BioProtoc.3017.
TheearlyentryofSalmonellainadistincttightcompartmentrevealedathightemporalandultrastructuralresolution. Fredlund J (#), Santos JC (#), Stévenin V (#), Weiner A, Rechav K,Mallet A, Krijnse-Locker J,ElbaumM,EnningaJ–(#)equalcontributors;CellMicrobiol,2017.doi:10.1111/cmi.12816
IdentifyingparametersofhostcellvulnerabilityduringSalmonellainfectionbyquantitativeimageanalysisandmodeling.VoznicaJ,GardellaC,BelotserkovskyI,DufourA,EnningaJ,StéveninV*-(*)correspondingauthor.InfectImmun,2017.doi:10.1128/IAI.00644-17.
FHODisneededfordirectedforcesandadhesionmaturationduringcellspreadingandmigration.IskratschT, Yu CH, Mathur A, Liu S, Stévenin V, Dwyer J, Hone J, Ehler E, Sheetz M. Dev Cell, 2013. doi:10.1016/j.devcel.2013.11.003.
Manuscriptinpreparation/submitted:
SizeregulationoftheSalmonella-containingvacuoledeterminesSalmonellaintracellularlifestyleinepithelialcells.StéveninV,ChangYY,LeToquinY,DuchateauM,GiaiGianettoQ,SohstV,ReilingN,MatonboM,EnningaJ.Researcharticle.inpreparation.
Cellularimagingofintracellularbacterialpathogens.StéveninVandEnningaJ.BookChapter.underrevision
FUNDINGS(Grantsandfellowships)05/2018-06/2018:2monthsPhDextensionfellowshipprovidedbythedepartmentofCellBiologyandInfectionofthePasteurInstitute(Paris,France).
10/2017-05/2018:7monthsPhDextensionfellowshipprovidedbythe“FoundationforMedicalResearch”(FRM).
09/2017:TravelgrantfortheEMBOConference:“Endocytictraffickingandsignalinginhealthanddisease”providedbytheFrenchSocietyforCellBiology(SBCF).
05/2017: Travel grant for the EMBO|EMBL symposium: “Molecular and Cell Biology of Membranes”providedby“GlobalCareInitiative-PasteurMicrobeetSanté”.
09/2014-09/2017:3years"Normalien"-specificPhDfellowship fromtheFrenchMinisterofResearchandEcoleNormaleSuperieure(ENS)deCachan(France).
09/2012-08/2014: "Normalien" status (highly selective French civil servant status for foundedundergraduatestudies)attributedbytheFrenchMinisterofResearchandtheÉcoleNormaleSupérieureofCachan(France).
09/2008-09/2012:FrenchMinistryofEducationmeritscholarship.
HONORS/PRIZES
03/2018:CoverimageoftheApril(2018)issueofCellularMicrobiology.
02/2018:Selectionofmyco-first-authorarticle,as“Editors’Choice”inCellularMicrobiology.
11/2017:Selectionofmy last-authorarticlebytheeditorsof Infectionand Immunity tobehighlighted in
the“Spotlight”sectionofthejournal.
09/2016: Award of the best poster during the 5th congress on Salmonella of the American Society forMicrobiology,Potsdam.
Lastupdate:November2018
SCIENTIFICPRESENTATIONSTalks:
05/2018: Invited atOsloUniversity Hospital, Institute for Cancer Research (Norway). Talk entitled: “NewinsightsonSalmonellaintracellularlifestyleinepithelialcells”
02/2018:1stMeetingonVesicularBiology(Coïmbra,Portugal).Shorttalkentitled:“ThevacuolarlifestyleofSalmonella in epithelial cells is determined at the early stage by the communication between distinctinfectionassociatedcompartments”
01/2018:InvitedattheLeidenUniversityMedicalCenter(TheNetherlands).Talkentitled:“NewinsightsonSalmonellaintracellularlifestyleinepithelialcells”
10/2017:2ndmeetingofthelaureatesoftheSchlumbergerFoundationforEducationandResearch(FSER),and their teams (Imagine Institute, Paris, France). Short talk entitled: “Communication between distinctinfectionassociatedcompartmentsdrivestheintracellularlifestyleofSalmonella”.
09/2017:EMBOConference“Endocytictraffickingandsignalinginhealthanddisease”.Shorttalkentitled:“Communication between distinct infection associated compartments drives the intracellular lifestyle ofSalmonella”.
03/2017:“Work-in-Progress”presentationfortheCellBiologyandInfectiondepartment(PasteurInstitute,Paris,France).Talkentitled:“QuantifyingthevulnerabilityofsinglehostcellstoSalmonellainfection”
11/2016:DepartmentaldayoftheCellBiologyandInfectiondepartment(PasteurInstitute,Paris,France).Short talk entitled: “The interactions between Infection Associated Macropinosomes and enteringSalmonelladetermineitsintracellularniche.”
05/2016:Conference“YoungResearchersinLifeSciences2016”(Paris,France).Shorttalkentitled:“Howtofeellikehome:DissectingthefirststepsofSalmonellaintracellularlife.”
Posters:10/2018:EMBOConference“Endoplasmicreticulumfunctioninhealthanddisease”(Lucca,Italy).
10/2017: Departmental retreat of the Cell Biology and Infection department of the Pasteur Institute(Pornichet,France).
09/2017:EMBOConference“Endocytictraffickingandsignalinginhealthanddisease”.
05/2017: EMBO|EMBL Conference “Molecular and Cell Biology of Membranes” (EMBL, Heidelberg,Germany).
10/2016:PasteurMeeting“QuantitativeBiologyKick-offMeeting”(PasteurInstitute,Paris,France).
09/2016:5thSalmonellaConferenceoftheAmericanSocietyforMicrobiology(Potsdam,Germany).
06/2015: Summer school FEBS/EMBO“Biomembranes: Molecular Architecture, Dynamics and Function”(Cargèse,France).
05/2015:Conference“YoungResearchersinLifeSciences2015”(Paris,France).
12/2012:Conference“AmericanSocietyforCellBiology”(SanFrancisco,USA).
SCIENTIFICEVENTSORGANIZED2016-2017: Organization of the scientific conference “Young Researchers in Life Sciences2017” (ImagineInstitute,Paris,France).
2015-2017: Coordinator for the association Animath proposing mathematical activities for high-schoolstudents.