Subject Index

Arid myropolysa,crharidcs 1,.-\)11') ] i ACTIl-glurororticoid sptem iiH Adions, adrcllcrgic 59 f\etivity, ostf'oelastie 1:29 Adjuvant arthritis 17;) Adrenal tortt'x t liB Adrenalin(' I7!) Adn'nalinr (A)- and blorki'r application 59 Adrenergic aetions 09 Age 205 _\gcing 121) Air pollution :243 AKR mice 185 Alcohol, toxieity 1i)3 Alcohol intakr, myoc.anliullI 1,)3 4-aminopyrazolopyrimidine (4-AP1') ] 1)9 AMP (aeiil mll('opolys<l('('harides) 17 i.\nalysis, automated mieroscopi(' 1 PI Anaplastic thyroid earrinoma 11 Antibody dcp('ndpnt eytotoxil'ity iJ;l Anti-tumor evtotoxieitv 33 Antral D-('clls 77 . Antral G-cells 77 Aorta 105 Aorta, cndothelillm 1!),3 Aortic endothelial eells, boviIH' KH Arteriosderosis 105, 193 Artery wall ] Arthritis, adjuvant 17i) Atherogenesis 193 Atherogenic diet 105 Atherosderosis 193 Atmospheric pollutants, toxieity 24i> Automated mieros('opir analysis 11;3

BALB/c mice 20,3 Betanaphthoflavonc 117 Bil(1 duet. ligation 205 BiUary eXl'J'etion :!D5 Biochcmital ('hanges 24!) Biotransformation, hl'patil' ,)3 Blood glucose 179 Bon n healing U9 Bone It'generation 129 Bowel, small 147 Brain (',dls 12f) Bronehial oel'iusion 243

Caleifieation, callus 129 Caldtollin 11 - renal les ions 17 Callus, bOlll' 129 Capillary-lik!- ~tru('tures til) Carcinoma, anaplastic thyroid 11 Careinomas, mammary 113 Cardiovaseular system 221 Cartilage, h yaline 129 Catecholamines 193 C-cell 11 Cell culture] ,ll, 193 Cell line, epithelial J 1)1 Cell proliferation 89 Cells, brain 125 Cellular immune reaction 33

VI

t"'ntralnNvoIlS syst!'m, lymphoma 185 Cerebral involvement 185 Cholesterol, dietary 105 Cirrhosis, liver 58 Classifieation, malignant tumors] 13 Coagulation, intravast ular 17i) Colthieine 1 Competition :W5 Corticosteron 59 Culture, tissue 89 CvtoehrOlll() P-450 117 Cytofluoromdry 47 Cytokrratin HH CvtoskPleton Hi! Cytotoxicity 33 - -, a,ntibocly d.ependent 33 ---, 11nti-tull1or 33 -, Illanophuge Hi)

Diabetes, streptozotoein-in(/u('cd 131 D-eells, autral 77 Degl'neratcd mito(·hondria 153 Deiodinasl' 179 J)('velopllll'nt, ontogenctir 117 Dog :20 Drugs , hepatic cX!:J'ction 95 --, J'l'nal I' X('fl,tion 95

}<~Ie('tri (',al stimulation 129 Endothelial cells, fibrin 89 --,proliferation 89 EndotheliuJIl , eytology 105 Enzyme induction 117 ~:piiirphrine 193 Epithelial ceillinc 161 Erythroeytcs, ('ytology 105 Ethoxveolllllarin O-dell1cthylation 117 Ethyl~lOrphine ~-r1emethylation 117 Ex(,\,{,tioll, biliary 205 Expl' ri llll'nta I pancreatitis :26

Fibrin, cUed on (mdotill'lillm 89 ~'ibrinoid ~:21 Fibroblast, gingiva 231 ~' , metabolism 231 Filaments, intermcdiatn 161 Formation, metastases 83 FraetllH" granulation tissue 129 Fradnre healing 129

H -('ells, antral 77 (;a.strie tumours 147 (:ustrin, serum level Ii Germinal flln d ion 249 Geroproteetors 125 Gestat,ion, hepati c cirrhosis 53 Gingiv1t 23J G IIll'ose, blood 179 (iTanulation tissue, fracture 129 Crowing rats 249

Healing, bone 129 i\J ierotilbules 1

hu('ttll'e 12f!

Heart, ah'oholic' r1amal!l' 1',:; Hepatectomy 117 Hepatic biotransformation f,B Hepatic eirrhosis [),l Hcpatie (>xeretioIl, drugs 96, 205 Histamine 39 Hyaline eartilag(' 129

IgA nephropathy 17 Image analysis ,automated mieroscopie 113 Immune reaction, cellular ,m Immune reactive insulin 179 Immunocytochemistry 77 Immunofluoresc!'nc(', vimcntin l(i L Indomethacin 95 Indueed tumours, stoma('h 147 Induttion, enzyme 117 -, plasmacytoma 263 Infaretion 175 Inflammation 39 Influence of lead 249 Insulin 231 --, immune f('udivc 179 Intermediate filaments 161 Involvement, ('erebral ] Sf) Isoprenaline, B-a,('tion 179

Kallikrein-kinin system rl9 Kappa-earrag(,l'nin 176 Kidney 17, 96 - , drng cxeretion 9,-) Kinin system '19

Laml~lIar bodil's 24,1 Lead 249 Leptomeninx IH:) Leydig cells 249 Ligation, bile dllct 206 Lipofusein 153 Lipoprotein (l efic'il'ney 169 Liver 26, 96 - - eirrhosis [);3 - - : drug l'xnction 9r) - -, ultrastrllcture 26 I,iver regeneration 117 Liver-'1'4-5'-deiodinasp 179 Lymphoma, malignant j 9f> ],ymphoma model 18i)

llIacrophage eytotoxieity ~t3 Malignaneies, elussifieation 11B Malignant fibrous histioeytom as, experimen-

tanv indll ced 83 "Malignant lymphoma 186 Mammary ta rcinomas 1 W MeasurelllPnt, oxygraphie 47 lVll'lllbrane, llIitoehondrial 4.7 Membrane potential 47 Mesangiolysis 17 Metastases formation SB 6-methyl-2-('thyl-3-oxyp~'ridine 126 Mi ce, A KR. l Si) ;\li('p, nud r Hi\ l'IIieIos{'opic image analysis, automated 113 Mitoehondria, degenerated 163 Mitoehonurial membrane 47

~1 ·:'-lKG (~-m!'thyl-N'-njtro-N-nitrosoguanjdinc) 147

Monooxygenase 117 Mucopolysa('C'harides 17 Mnscle ('cll, smooth 1 Mnsell' ('ells, smooth 193 ?lfvocardillJll, akohol intake 153 ~l~'ofibrils IH1

Nephreetomy 205, 221 Nephropathy, kidney 17 ~l'rvolls system, lymphoma 185 ~-m(·thyl-X' -nitro-N-nitrosogua,nidine (M:.'l" NO)

147 Norepinephrine 193 Nllde mite 1:\3

Offspring, hepatie biotransformation 53 Ontogenetic development 117 Osteoclastic activitv 129 Ostl'oid 129 • Osteotomv 129 Oxygmpllie measurement 47

Pancreatitis , experiml'ntal 25 Pericarditis 221 Periosteum 129 Phenobarbital 117 Phenol red (llimination, kidney 205 -, liver 206 Phenol red ('x('fption 95 Plasma 193 Plasma riot culture 89 Plasmacvtoma. induction 253 Plasmu('ytomagenesis 253 Pnenlllo('yt('s type II 243 Polvsolll es .I2[J Potl'ntial, lllembrane 47 PIP('('ding stages , tumours 113 Pregnan('y, h('patic drrhosis !i3 Prenoeoplasms 113 l'ristanp (2,ti ,lO,14-tetramethylppntadeeane) 253 Propanolol (Prop) 59 Prostatvrlin 26 Protein 's vnthpsis 126 I'lllmona i'~' ('ollaps(' 243

Radioimmunoassav 77 Rat 153, 169, 249 · . -, bone 129 Rpgt'neration, liver 117 Rej('('tion , tumor 33 Renal excretion, drugs 95, 205 Renal failure 221 Renullesioll , ('aleitonin 17 Reproductive system 249 Reseetioll, small bowel 77 Rptienlllm, sarcoplasmic 153 Rhodamine G G 47

SaT('oplasmic reticulum 153 Scphadpx model 39 Serum factors 231 Srxual matnrity 249 Small bowel 14'7 Small bowl'! j'{'sl\etion 77

VII

Sma ll inti's till". illdll t"<, ,, tilin or, 1·+/ Smooth musr!C' rell~ I, J!n Spl'rmatogl'llPsis, dist lirhan, ·C's :!.t!J Spontaneous tlllllors 1 S:l Stages, prr(·(' dill~ of ti ll l,,) rS 1 H Staining, vital +7 Strrcolog;y Hi!:! ~timlliation, ('II'(·trl!'u i 1:?9 Stomaeh, in<ilH'p(1 tumo rs 14, i:itreptozoto('in-ilHhll'pd dia Il<' tl" l :i I Surfactant :!.t:l i:iynthl'sis, protPin 1 :! ()

T AA (thioaeeta midp) .);) 'J\ -ii'-deiodinase 17:) Testis 249 Tetramcthyipentad('eU1H' I Pristan" ) :!5J Thioacetamidr (TAA) 1):3 Thrombosis I i5 Thyroid neoplasia. I I Tisslle mlturp S$J

VIn

:1:i8SIII' fI ' pair, f ih t: i'~ ,:'\~l 1 O\I('ltV, alrohol. I ,);) 'I' nbnli,; 1 TUlllor rt',icrtion 33 THlllor progression il3 '('lIlllor transplantation Hi;) '!'IIIHors, C'l assifiration 11:l . . spontanrons lilii

, III.inary bl adder 113 Tilmors, gastr ie 147 ' . indu "I'd, slllall int,'stilH' 147

" stoma('h 147 - , pre('('ding stages 11;) TypC' II pnl'llll1o('ytes 243

U trast rtleture, li ver 25 Urinary bl addN tnmors 113

Vimentin , imlllllnofhlOIcsccn('e 161 Vital staining 47