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86 JCC, Vol. 42, N o 2, avril 1999 Surgical Images Imagier chirurgical SOFT-TISSUE IMAGES. ADRENOCORTICAL ADENOCARCINOMA PRESENTING AS CONNS SYNDROME A drenal adenocarcinoma rarely presents with hyperaldostero- nism (Conn’s syndrome), which usu- ally presents as chronic hypertension with hypokalemia. In severe cases of hyperaldosteronism, profound weak- ness with bizarre aches and pains may occur acutely. A 29-year-old woman presented to the emergency department with severe malaise, profound weakness and nau- sea plus chest and abdominal pains of fleeting duration. Investigation to rule out biliary tract disease included ultra- sonography, which revealed a large left upper abdominal mass. Subsequent CT (Figs 1 and 2) and MRI demonstrated a massive adrenal tumour extending through the left renal vein into the vena cava and upward to the heart. Labora- tory investigations demonstrated severe hypokalemia and a high serum aldos- terone level with low renin levels. Surgical management consisted of a sternotomy and abdominal approach with the aid of cardiopulmonary by- pass to remove the entire mass, in- cluding the left kidney and intracaval extension of the tumour thrombus to the right atrium (Fig. 3). Her recov- ery was uncomplicated. Management has continued with observation and chemotherapy, although a metastatic pulmonary lesion has developed. Adrenocortical adenocarcinoma is a lethal disease, requiring aggressive resection if possible. Chemotherapy and radiotherapy have given disap- pointing results, so recurrent disease is best managed by repeat resection also, if feasible. Unresectable disease has a uniformly poor outcome. 86 JCC, Vol. 42, N o 2, avril 1999 Section Editors: David P. Girvan, MD, and Nis Schmidt, MD Submitted by Nis Schmidt, MD, Department of Surgery, University of British Columbia, Vancouver, BC. Submissions to Surgical Images should be sent to Dr. David P. Girvan, Victoria Hospital Corporation, PO Box 5375, Station B, London ON N6A 5A5 or to Dr. Nis Schmidt, Department of Surgery, St. Paul’s Hospital, 1081 Burrard St., Vancouver BC V6Z 1Y6, with a copy of the submitting letter to Dr. Jonathan L. Meakins, Rm. S10.34, Royal Victoria Hospital, 687 Pine Ave. W, Montreal QC H3A 1A1. © 1999 Canadian Medical Association FIG. 1. Transverse section of the abdomen through the liver and the mass. 1 = liver, 2 = adrenal tu- mour filling renal vein and vena cava, 3 = blood flow in the vena cava; white crescentic line indicates blood in the lumen of the vessel. 1 3 2
Transcript
Page 1: Surgical Images Imagier chirurgical - Canadian Journal of ...canjsurg.ca/wp-content/uploads/2014/03/42-2-86.pdf · Surgical Images Imagier chirurgical SOFT-TISSUE IMAGES. A DRENOCORTICAL

86 JCC, Vol. 42, No 2, avril 1999

Surgical ImagesImagier chirurgical

SOFT-TISSUE IMAGES. ADRENOCORTICALADENOCARCINOMA PRESENTING AS CONN’S SYNDROME

Adrenal adenocarcinoma rarelypresents with hyperaldostero-

nism (Conn’s syndrome), which usu-ally presents as chronic hypertensionwith hypokalemia. In severe cases ofhyperaldosteronism, profound weak-

ness with bizarre aches and pains mayoccur acutely.A 29-year-old woman presented to

the emergency department with severemalaise, profound weakness and nau-sea plus chest and abdominal pains of

fleeting duration. Investigation to ruleout biliary tract disease included ultra-sonography, which revealed a large leftupper abdominal mass. Subsequent CT(Figs 1 and 2) and MRI demonstrateda massive adrenal tumour extendingthrough the left renal vein into the venacava and upward to the heart. Labora-tory investigations demonstrated severehypokalemia and a high serum aldos-terone level with low renin levels.Surgical management consisted of

a sternotomy and abdominal approachwith the aid of cardiopulmonary by-pass to remove the entire mass, in-cluding the left kidney and intracavalextension of the tumour thrombus tothe right atrium (Fig. 3). Her recov-ery was uncomplicated. Managementhas continued with observation andchemotherapy, although a metastaticpulmonary lesion has developed.Adrenocortical adenocarcinoma is

a lethal disease, requiring aggressiveresection if possible. Chemotherapyand radiotherapy have given disap-pointing results, so recurrent diseaseis best managed by repeat resectionalso, if feasible. Unresectable diseasehas a uniformly poor outcome.

86 JCC, Vol. 42, No 2, avril 1999

Section Editors: David P. Girvan, MD, and Nis Schmidt, MD

Submitted by Nis Schmidt, MD, Department of Surgery, University of British Columbia, Vancouver, BC.

Submissions to Surgical Images should be sent to Dr. David P. Girvan, Victoria Hospital Corporation, PO Box 5375, Station B, London ON N6A 5A5 or to Dr. Nis Schmidt,Department of Surgery, St. Paul’s Hospital, 1081 Burrard St., Vancouver BC V6Z 1Y6, with a copy of the submitting letter to Dr. Jonathan L. Meakins, Rm. S10.34, RoyalVictoria Hospital, 687 Pine Ave. W, Montreal QC H3A 1A1.

© 1999 Canadian Medical Association

FIG. 1. Transverse section of the abdomen through the liver and the mass. 1 = liver, 2 = adrenal tu-mour filling renal vein and vena cava, 3 = blood flow in the vena cava; white crescentic line indicatesblood in the lumen of the vessel.

1

3

2

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SURGICAL IMAGES

CJS, Vol. 42, No. 2, April 1999 87

FIG. 2. Coronal section of the abdomen and adrenal mass. 1 = liver, 2 =adrenal tumour extending into the vena cava upward above the hepaticveins to the right atrium (3), 4 = blood flow in the vena cava.

1

2

3

4

FIG. 3. Resected adrenal tumour with intracaval tumour thrombus superim-posed on the coronal CT scan. 1 = liver, 2 = adrenal tumour, 3 = kidney, 4 =vena cava with tumour thrombus, 5 = ovarian vein with tumour thrombus.

1

2

3

4

5

Trauma and critical care

The American College of Surgeons’ Com-mittee on Trauma will present a programentitled “Trauma and Critical Care ’99 —Point/Counterpoint XVIII.” The venuewill be Bally’s Park Place, Atlantic City, NJ,May 23 to 26, 1999. The course objectivesare to review the latest developments in thecare of the acutely injured patient; to re-examine current diagnostic and treatment ap-proaches and describe alternative methods;to describe the latest operative techniques in dealing with life- and limb-threatening injuries; to present challenging case man-agement scenarios and offer advice regard-ing difficult diagnostic, therapeutic andtechnical challenges; to critically examinethe emerging role of clinical practice guide-

lines and determine their place in the oveallmanagement of injured patients; to addresscurrently mandated documentation andcoding issues; and to simplify ventilatormanagement while adopting an aggressivetreatment approach to respiratory failure intrauma patients. The faculty comprises Drs.L.D. Brit, S. Brotman, D. Feliciano, P.Letarte, R. Orlando, III, L.H. Pachter,C.W. Schwab and D.D. Trunkey. Credit:23 hours in ACME Category 1. Registra-tion fee is US$525 on or before Apr. 20,1999 or $US595 thereafter. For further in-formation contact Ms. Carol Williams,Trauma Department, American College ofSurgeons at tel. 312 202-5342, [email protected] or www.facs.org/about college/acsdept/trauma dept/cme/traumtgs .html

Breast, endocrine and cancer surgery

The Department of Surgery, University ofMinnesota Medical School will sponsor its63rd annual course on advances in breast,endocrine and cancer surgery to be held atWilley Hall, University of Minnesota, Min-neapolis, Minn. from June 16 to 18, 1999.Credit: AMA Category I. Fees are US$550($US350 for medical residents). For further information contact: Office of Continuing Medical Education, Universityof Minnesota, 107 Radisson HotelMetrodome, 615 Washington Ave. SE,Minneapolis MN 55414; tel 612 626-7600 or 800 776-8636, fax 612 626-7766, www.med.umn.edu/cme

Continued on page 88

NoticesAvis


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