THE EXCRETORY SYSTEM(AKA THE URINARY SYSTEM)
FUNCTIONS OF THE URINARY SYSTEM
• Elimination of waste products
• Nitrogenous wastes = uric acid
• Toxins
• Drugs
• Regulation of homeostasis by maintaining balanced levels of:
• Water
• Electrolytes
• Acid-base in the blood
• Blood pressure
• Red blood cell production
• Activation of vitamin D
ORGANS OF THE URINARY SYSTEM
• KIDNEYS
• URETERS
• URINARY BLADDER
• URETHRA
KIDNEY
• Two bean shaped structures
• Extract waste from the blood
• Form urine
STRUCTURES OF THE KIDNEYS
• Nephrons = the filtering units of the kidneys
• Responsible for forming urine
• Main structures of the nephrons:
oGlomerulus
oRenal tubule
GLOMERULUS
• A specialized bundle ofcapillaries
• Attached to arterioles on both sides to maintain an even pressure
• Filtration system
RENAL TUBULE• Carries fluids to the glomerulus
• Made up of the:
o Glomerular (Bowman’s) capsule
o Proximal convoluted tubule
o Loop of Henle
o Distal convoluted tubule
TYPES OF NEPHRONS
• CORTICAL NEPHRONS
o Located entirely in the cortex
(outer portion of the kidney)
• JUXTAMEDULLARY NEPHRONS
o Found at the boundary of the
cortex and medulla (inner portion
of the kidney)
URINE FORMATION PROCESSES
URETERS
• Slender tubes attaching the
kidney to the bladder
• Peristalsis (rhythmic
contractions) aids gravity in
urine transport
URINARY BLADDER
• Smooth, collapsible, muscular sac
• Temporarily stores urine
• Trigone = three openings
• Two from the ureters
• One to the urethra
• Walls consist of:
o Three layers of smooth muscle
o Mucosa made of transitional
epithelium
• Can expand significantly without
increasing internal pressure
URETHRA
• Thin-walled tube that carries urine from the bladder to the outside of the body by peristalsis
• Females – only carries urine
• Males – carries urine and is a passageway for sperm cells
• Release of urine is controlled by two sphincters
• Internal urethral sphincter (involuntary)
• External urethral sphincter (voluntary)
FUN FACT!
A sphincter is a ring of muscle that opens and closes a tube.
Believe it or not you have over 50 sphincters in your body.
Learn more about them in this video:
https://www.youtube.com/watch?v=gtLO9rpXV0g
MICTURITION (VOIDING)
• Both sphincter muscles must open to allow voiding
• The internal urethral sphincter is automatically relaxed after
stretching of the bladder
• The external urethral sphincter must be voluntarily relaxed
MAINTAINING WATER BALANCE• Water intake must equal water output
• Sources for water intake
• Ingested foods and fluids
• Water produced from metabolic processes
• Sources for water output
• Vaporization out of the lungs
• Lost in perspiration (sweat)
• Production of saliva and tears
• Leaves the body in the feces
• Urine production
• Regulation is primarily by hormones
• Antidiuretic hormone (ADH) prevents excessive water loss in urine
• Aldosterone regulates sodium ion content of extracellular fluid
• Cells in the kidneys and hypothalamus are active monitors of water and electrolyte balance
MAINTAINING ACID-BASE BALANCE IN BLOOD• Blood pH must remain between 7.35 and 7.45 to maintain homeostasis
• Alkalosis – pH above 7.45
• Acidosis – pH below 7.35
• Most ions originate as byproducts of cellular metabolism
• Most acid-base balance is maintained by the kidneys
• Other acid-base controlling systems
• Blood buffers
• Respiration