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573 THE SPREAD OF TUBERCULOSIS. of defaulters, and the location of centres apart from hospitals does not seem to deter patients. A warning is sounded against inadequate treatment. A short course of arsenobenzol and mercury is often followed by relapse, and it is important that medical officers should be convinced of the necessity for prolonged treatment. Practitioners are reminded that the signs of venereal disease in pregnancy are often absent or very slight, and are urged to follow up the clue given by infected children or stillbirths. Treatment of the congenitally syphilitic child, also, should be com- menced while the disease is latent and doctors should act on suspicion. Experience in Plymouth has shown that detection of the disease before it is manifest would considerably raise the standard of health of the population. Maternity and Child Welfare. This work has been expanded and the gloomy fore- bodings as to the effect of the strike on the physique and vigour of school-children were not fulfilled, partly as the result of provision of meals at school and the distribution of free milk. The maternal mortality-rate was 4-12, a slight rise. The importance of making provision for treatment of puerperal pyrexia and for antenatal supervision is stressed. There are now 772 antenatal centres, 105 homes for unmarried mothers, and 2324 infant welfare clinics. The report remarks that money expended on centres and health visitors brings perhaps a greater return than any other form of expenditure on maternity and child welfare, and points out that the Adoption of Children Act, 1926, may prove prejudicial to the welfare of illegitimate children, whose foster mothers may adopt them to avoid supervision. Although provision for ophthalmia neonatorum is good in most areas there still seem to be administrative loopholes, and the responsibility for notification has now been laid wholly on the medical practitioner. The care of the pre-school child is described as a problem awaiting satisfactory solution. Dr. Margaret Hogarth’s examination of 1000 unselected children of 3 years of age revealed a large amount of preventable disease, but also created an impression of a much higher standard of parental care than was evident ten years ago. The most striking feature was the prevalence of rickets, the forerunner of all that is required to produce a C3 nation. The effects of treat- ment by sunlight and cod-liver oil appear to wear off when the course is discontinued. Diseases of the throat, nose, and ear formed an important group of defects, and the prevention of otitis media and of the sequelse of enlarged tonsils and adenoids alone make systematic supervision desirable. Special attention is drawn to the danger of forgetting the mental develop- ment of the child through focusing attention on his physical welfare. The Conference on Child Welfare, held at Geneva in September, agreed to investigate the value of preventive measures against scarlet fever, diphtheria, and measles, to prepare a note on the arrangements in different countries for the training in pediatrics of doctors, nurses, and health visitors, and to hold an inquiry into infant mortality in selected districts over a period of 12 months. The areas chosen in England were Sunderland and parts of Staffordshire (high rate) ; Croydon and Oxfordshire (low rates). This is the first international inquiry of the kind, and is to be clinical rather than statistical. N at’ional Health Insurance. The number of persons entitled to benefit in 1926 was 14,102,000, one-third of the population, bread- winners on whose health and capacity the living of the great majority of the remainder was dependent. Increase in the number of certificates during the strike and in the aggregate cost of prescribing are commented on. Late in the year six full -time regional dental officers were appointed and dental benefit is now almost universal. More than £400,000 a year has been allocated to ophthalmic benefit. The statement that the service " does not tend to the prevention of disease " is strongly combated and the educational work carried on by panel committees is reviewed. Food in Health and Disease. Gratification at the awakening of public interest in diet is expressed, and caution and discrimination in making didactic statements are called for. Recent research has shown that the keynote of a successful diet is variety and has thrown doubt on the belief that primitive man was better off in regard to his diet than man of the present day. It is pointed out that this country is eminently suited to the production of the essential foods, milk, and vegetables, and that they should be distributed widely and cheaply enough for them to be in everybody’s daily diet. Describing the improvements in milk preparation the report states that there has been a satisfactory increase in the amount of Grade A (T.T.) milk supplied. Great stress is laid on cooperation between M.O.H., public analyst, and sampling officers. There is immense and con- tinuing improvement in purity of foodstuffs, and more tests for preservatives were carried out during the first two months of the year than during the whole previous decade. Analytical methods need revision, especially for traces of boric acid, and this has been the main work of the laboratory. Forty-eight food- poisoning outbreaks are reviewed. Research Work. Work on the haemolytic streptococci has been published and supports the view that these organisms. are the cause of scarlet fever. Some research on pneumococcal virulence and immunity will be com- pleted shortly. A good deal of statistical analysis was. done for the Scarlet Fever Committee and on school anthropometry. The factors in puerperal mortality have been investigated, as have also the incidence of disease in cotton-spinners in wet and dry sheds, and health in the printing industry. It is becoming clear that the conception of herd immunity as distinct from individual immunity is a very important one for prophylaxis. The steady increase in the number of requests for advice and help in research work arising out of the ordinary duties of medical officers is viewed with great satisfaction as the most valuable work of the department. A review of progress in artificial light treatment lays stress on the necessity for medical control and supervision. A disquieting increase is noted in the deaths from anaesthesia, and the Ministry is anxious to ascertain the real fatality ratio and to relate it to different anaesthetics and methods of administration. International Health. The report concludes with a review of the work of the League of Nations Health Committee, the Office International, the International Sanitary Conference in June, and the International Pacific Health Confer- ence. Other chapters deal with the Port Sanitary Authority and the Poor-law. THE SPREAD OF TUBERCULOSIS. EXAMINATION OF CONTACTS. THE eradication of tuberculosis depends on the solution of a problem that has hitherto baffled an army of investigators. The problem is concerned with the manner of its spread. A husband, for instance, is consumptive ; his wife, subject to daily and nightly opportunities for infection, apparently escapes the disease. One child, perhaps, dies of miliary tuberculosis, two or three children become " tuberculous seedlings," and after a school career, chequered by frequent visits to clinics, dispensaries, and sanatoriums, reach adult life without revealing any obvious signs of tuberculous disease. In another similarly infected family, by contrast, the children pass through school life apparently free from disease, but when adolescence is reached, one or more of them suddenly develops signs of active phthisis, possibly many years after the death of the consumptive parent. In some cases the tragedy of " Wuthering Heights "
Transcript
Page 1: THE SPREAD OF TUBERCULOSIS

573THE SPREAD OF TUBERCULOSIS.

of defaulters, and the location of centres apart fromhospitals does not seem to deter patients. A warningis sounded against inadequate treatment. A shortcourse of arsenobenzol and mercury is often followedby relapse, and it is important that medical officersshould be convinced of the necessity for prolongedtreatment. Practitioners are reminded that the signsof venereal disease in pregnancy are often absent orvery slight, and are urged to follow up the clue givenby infected children or stillbirths. Treatment of thecongenitally syphilitic child, also, should be com-menced while the disease is latent and doctors shouldact on suspicion. Experience in Plymouth has shownthat detection of the disease before it is manifestwould considerably raise the standard of health of thepopulation.

Maternity and Child Welfare.This work has been expanded and the gloomy fore-

bodings as to the effect of the strike on the physique andvigour of school-children were not fulfilled, partly asthe result of provision of meals at school and thedistribution of free milk. The maternal mortality-ratewas 4-12, a slight rise. The importance of makingprovision for treatment of puerperal pyrexia and forantenatal supervision is stressed. There are now 772 antenatal centres, 105 homes for unmarriedmothers, and 2324 infant welfare clinics. The reportremarks that money expended on centres and healthvisitors brings perhaps a greater return than any otherform of expenditure on maternity and child welfare,and points out that the Adoption of Children Act, 1926,may prove prejudicial to the welfare of illegitimatechildren, whose foster mothers may adopt them toavoid supervision. Although provision for ophthalmianeonatorum is good in most areas there still seem to beadministrative loopholes, and the responsibility fornotification has now been laid wholly on the medicalpractitioner.The care of the pre-school child is described as a

problem awaiting satisfactory solution. Dr. MargaretHogarth’s examination of 1000 unselected children of3 years of age revealed a large amount of preventabledisease, but also created an impression of a muchhigher standard of parental care than was evidentten years ago. The most striking feature was theprevalence of rickets, the forerunner of all that isrequired to produce a C3 nation. The effects of treat-ment by sunlight and cod-liver oil appear to wear offwhen the course is discontinued. Diseases of thethroat, nose, and ear formed an important group ofdefects, and the prevention of otitis media and of thesequelse of enlarged tonsils and adenoids alone makesystematic supervision desirable. Special attention isdrawn to the danger of forgetting the mental develop-ment of the child through focusing attention on hisphysical welfare. The Conference on Child Welfare,held at Geneva in September, agreed to investigatethe value of preventive measures against scarlet fever,diphtheria, and measles, to prepare a note on thearrangements in different countries for the trainingin pediatrics of doctors, nurses, and health visitors,and to hold an inquiry into infant mortality in selecteddistricts over a period of 12 months. The areas chosenin England were Sunderland and parts of Staffordshire(high rate) ; Croydon and Oxfordshire (low rates).This is the first international inquiry of the kind, andis to be clinical rather than statistical.

N at’ional Health Insurance.The number of persons entitled to benefit in 1926

was 14,102,000, one-third of the population, bread-winners on whose health and capacity the living of thegreat majority of the remainder was dependent.Increase in the number of certificates during the strikeand in the aggregate cost of prescribing are commentedon. Late in the year six full -time regional dentalofficers were appointed and dental benefit is nowalmost universal. More than £400,000 a year hasbeen allocated to ophthalmic benefit. The statementthat the service " does not tend to the prevention ofdisease " is strongly combated and the educationalwork carried on by panel committees is reviewed. ’

Food in Health and Disease.Gratification at the awakening of public interest in

diet is expressed, and caution and discrimination inmaking didactic statements are called for. Recentresearch has shown that the keynote of a successfuldiet is variety and has thrown doubt on the belief thatprimitive man was better off in regard to his diet thanman of the present day. It is pointed out that thiscountry is eminently suited to the production of theessential foods, milk, and vegetables, and that theyshould be distributed widely and cheaply enough forthem to be in everybody’s daily diet. Describing theimprovements in milk preparation the report statesthat there has been a satisfactory increase in theamount of Grade A (T.T.) milk supplied. Great stressis laid on cooperation between M.O.H., public analyst,and sampling officers. There is immense and con-tinuing improvement in purity of foodstuffs, and moretests for preservatives were carried out during thefirst two months of the year than during the wholeprevious decade. Analytical methods need revision,especially for traces of boric acid, and this has beenthe main work of the laboratory. Forty-eight food-poisoning outbreaks are reviewed.

Research Work.Work on the haemolytic streptococci has been

published and supports the view that these organisms.are the cause of scarlet fever. Some research onpneumococcal virulence and immunity will be com-pleted shortly. A good deal of statistical analysis was.done for the Scarlet Fever Committee and on schoolanthropometry. The factors in puerperal mortalityhave been investigated, as have also the incidence ofdisease in cotton-spinners in wet and dry sheds, andhealth in the printing industry. It is becoming clearthat the conception of herd immunity as distinct fromindividual immunity is a very important one for

prophylaxis. The steady increase in the number ofrequests for advice and help in research work arisingout of the ordinary duties of medical officers is viewedwith great satisfaction as the most valuable work ofthe department. A review of progress in artificiallight treatment lays stress on the necessity formedical control and supervision. A disquietingincrease is noted in the deaths from anaesthesia, andthe Ministry is anxious to ascertain the real fatalityratio and to relate it to different anaesthetics andmethods of administration.

International Health.The report concludes with a review of the work of

the League of Nations Health Committee, the OfficeInternational, the International Sanitary Conferencein June, and the International Pacific Health Confer-ence.

Other chapters deal with the Port Sanitary Authorityand the Poor-law.

THE SPREAD OF TUBERCULOSIS.EXAMINATION OF CONTACTS.

THE eradication of tuberculosis depends on thesolution of a problem that has hitherto baffled anarmy of investigators. The problem is concernedwith the manner of its spread. A husband, forinstance, is consumptive ; his wife, subject to dailyand nightly opportunities for infection, apparentlyescapes the disease. One child, perhaps, dies ofmiliary tuberculosis, two or three children become" tuberculous seedlings," and after a school career,

chequered by frequent visits to clinics, dispensaries,and sanatoriums, reach adult life without revealingany obvious signs of tuberculous disease. In anothersimilarly infected family, by contrast, the childrenpass through school life apparently free from disease,but when adolescence is reached, one or more of themsuddenly develops signs of active phthisis, possiblymany years after the death of the consumptive parent.In some cases the tragedy of " Wuthering Heights

"

Page 2: THE SPREAD OF TUBERCULOSIS

574 BERLIN.

is repeated and a family is decimated ; in others t

& single member of the second generation succumbs. Not infrequently, again, an adolescent or young adult idevelops phthisis although the family bill of health (

is clear of any taint of the disease and no source of infection can be traced. The origin of the chronic fibroid type of tuberculosis common in later life is 1

equally uncertain, and it is often doubtful in any (

particular case whether the infection is of recent dateor whether declining vitality has caused a smoulderingfire to blaze. Where much is obscure certain facts are patent.

That a member of a family suffering from manifesttuberculosis is a grave source of danger to all its members has been recognised since Koch’s discovery,and, indeed, was recognised before it, and provisionfor the examination of contacts is considered to bean essential part of all antituberculosis schemes.When a case of tuberculosis is notified a health visitorcalls at the home of the sufferer, and though the adoles-cent members of the family are apt to decline toattend the dispensary, maternal anxiety can usuallybe depended upon to produce two or three infantsor children of school age. These are martialled beforethe tuberculosis officer, a physical examination ismade, the signs of manifest tuberculosis are lacking,and a much-relieved parent returns with her wonderingoffspring to the home where infection abides. Finally,a record of negative results for the contacts is dulyreturned to swell the satisfactory statistics of thecounty medical officer, regardless of the fact that topronounce an infant " free from any trace of thedisease," because auscultation and percussion failto reveal obvious signs of tubercle is about as usefulas to palpate its chin and report that there is noevidence of a beard.The familial spread of tuberculosis can never be

prevented by such perfunctory methods and slipshodwork. It is notorious that pulmonary tuberculosis isonly recognisable by physical signs in the chest whenthe disease is firmly established. The " early case "of the sanatorium is not an early case of tuberculousinfection ; the sound of cracking timbers, the fall ofdecayed masonry are not the signs by which a housinginspector determines incipient decay in a building.For too long the threatenings of imminent collapsehave been mistaken for the first warnings of danger.The slogan of the propagandist, that consumption iscurable in its early stages, is only true if appliedto stages whose detection requires far greater delicacythan that of palpation, percussion, and auscultation.

In this connexion the work of E. L. Opie and F. M.McPhedran.1 of Philadelphia, deserves more attentionthan it has yet received in this country. Theirinvestigation of tuberculous contagion in familieshas been based upon evidence obtained from the Iintracutaneous tuberculin test, correlated withinformation from skiagrams, and supplemented bythe usual physical examination. In this way bothcontact and non-contact families have been subjectedto a searching examination, the results for each

family being set out on an ingenious record cardshowing diagrammatically the condition of eachmember as revealed by the various tests employed.The age of each member is also shown and the durationof exposure to infection in the case of " contact

"

families is graphically indicated.The tuberculous are divided into (a) those with

manifest disease recognisable by physical signs,sputum tests, &c., and (b) those with latent diseaseonly revealed by radiographic examination andtuberculin tests. Latent infection in the child isdue to implantation of the tubercle bacillus in thelymphatic system of the lungs and is revealed bynodes in the lung field or by enlargement of thetracheobronchial glands ; the radiographic appear-ance of these foci has been compared with post-

1 The Contagion of Tuberculosis. By Eugene L. Opie, M.D.,and F. Maurice McPhedran, M.D. The American Review ofTuberculosis, October, 1926. Spread of Tuberculosis withinFamilies. By Opie and McPhedran. Journal of the AmericanMedical Association, No. 1926.

mortem findings and their signincance has beenproved. The adult type of latent infection—whichis, however, occasionally found in children—ischaracterised by involvement of the lung apex, whichmay be the seat of tuberculous deposits or mayexhibit a thickening of the apical cap. It is claimedthat the X ray findings are confirmed by the intra-cutaneous test, though the latter is more delicateand supplies evidence of infection at an earlier stage.

If the conclusions of Opie and Mcl’hedran are

correct, they ought to be generally applied as far asmay be possible. They are as follows :-

1. When latent tuberculosis is taken into con-

sideration, tuberculosis exhibits the chanacters ofa contagious disease and affects all children of house-holds within which some members, suffering withtuberculosis, scatters tubercle bacilli.

2. Recognition of latent apical tuberculosis hasdemonstrated that tuberculous infection is transmittedto adults and to adolescent children, and has shownthat approximately one-half of the partners ofhusbands and wives with open tuberculosis are

infected after marriage.3. Duration of exposure to open tuberculosis is

an important factor in determining the characterand severity of the resulting infection ; in instancesof recognisable tuberculosis of tracheobronchial lymphnodes the average duration of contact with tuber-culosis has been approximately four and a half years,and instances of latent apical tuberculosis nearlytwice as much.

4. Dispensaries for the care and control of tuber-culosis should be organised so that spread of latentinfection within the family may be recognised andprevented. A chart for each family, depicting theseverity of latent and manifest disease disclosed byquantitative tuberculin reactions and roentogeno-logical examination, will forcibly direct attention toeffective means of control.

5. Latent tuberculosis often becomes manifest.Certain forms of latent infection foretell the approachof clinically recognisable disease. These are (1) infec-tion recognisable by the tuberculin reaction during

- the first two years of life, (2) tracheobronchial tuber-culosis in children recognised by roentogenological

; examination, and (3) latent apical tuberculosis inadolescent children. Children with these forms of

i tuberculous infection should be examined at frequentintervals and treated as though they had recently

- arrested tuberculosis.6. All adults in whom latent apical tuberculosis

has been recognised should receive the same care aspatients with arrested phthisis.

BERLIN.

(FRmr OUR OWN CORRESPONDENT.)

Abortion in Russia and in Germany.THE Breslau Medical Society recently discussed the

consequences of legalised abortion in Russia. Thenew legislation in that country recognises no differencebetween children born in and out of wedlock, andthe Soviet has decreed that any abortion sanctionedby a medical commission and performed in a publichospital by a doctor will not be regarded as criminal.As a result of this decree so many women appliedfor abortion that the hospitals were soon overcrowdedand private sanatoriums had to be used. The Sovietauthorities intended that abortion should no longerbe concealed, and that women who wished theirpregnancy to be interrupted should be able to getthis done under favourable circumstances. Theywanted to prosecute those who make a business ofartificial abortion, and not the mothers who seek tohave the operation performed. Needless to say, theresult has been a great increase of abortion, andaccording to Dr. Niedermeyer, who opened thediscussion, only a nation of such vitality as Russiacan stand such legislation. Abortion performed by


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