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The use of Rapid HIV test in low threshold testing center is … · Introduction Methods Results...

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Introduction Methods Results CONCLUSION The Antwerp Helpcenter (HC) is a low threshold center for HIV and STI tesng and dedicated to high risk groups: men having sex with men (MSM) and migrants from high endemic regions (mostly Sub Saharan African migrants, SAM). Rapid HIV tests (RT) are used at the HC for HIV screening since June 2007. The aim of this work is to describe our experience with this tesng strategy. A retrospecve analysis of all Rapid Test rounely performed at HC. The Determine®HIV-1/2 (3th generaon) was used as the RT unl May 2009 and thereaſter the Determine Combo®HIV-1/2 Ag/Ab (Alere) test (4th generaon). All reacve tests were confirmed using INNO-LIA HIVI/II Score®. A validaon study was performed on 310 samples at the beginning of the project. By December 2012, 5025 Rapid Test had been performed on 3884 persons including 1209 MSM and 455 SAM migrants in the Helpcenter The mean age of clients was 34 years. Tables 1-3, fig 1. The availability of RT was an important reason to consult at HC, 66% of the respondents highlight it as movaon to consult at HC. RT is of- fered to each person consulng at HC, 90% of them accepted to undergo a RT as screening for HIV. Figure 2. Of 59 confirmed new diagnoses, at least 50 were linked to care (84.75%). • The overall prevalence of HIV infecon in our test center was 1.5 %. In the two main target groups the prevalence was much higher: MSM 3,9% and SAM 2,2% • At least 85% of new diagnoses made with RT were successfully linked to care. • The relavely high proporon of posive RTs that were found to be HIV negave on confirmatory tesng (12%) should act as reminder of the importance of adequate counseling and confirmatory strategy when using these rapid tests. • The HIV Rapid Test was well accepted in a dedicated tesng center and aracted many people to get tested. It is cheap, has a fast turnaround me and is easy to perform. • It can be used in VCT centers were people at higher risk are aracted (e.g. services aimed at MSM, migrants from high endemic regions, commercial sex workers, injecng drug users). • It is of parcular ulity in sengs where there is a high risk that the client will not return for the result. Rapid tests Number % Total RT performed 5025 100 Positive 74 1.5 Negative 4945 98.4 Not interpretable 6 0,1 Table 1: Results of the RapidTests Table 2: Results of the confirmatory tests Figure 1: New HIV diagnoses in risk groups Figure 2: Acceptance of RT Table 3: New HIV diagnoses in risk groups Confirmation test Number % Total RT performed 74 100 Confirmation positive 58 78.4 Confirmation indeterminate, 1 1,4 antigen positive Confirmation negative 9 12,2 Already confirmed before 6 8.1 Risk group HIV+ Total % of tests in 95% Conf. risk group Interval MSM 47 1209 3.9 [2.9-5.1] SAM 10 449 2.2 [1.2-4.1] other 2 2220 0.09 [0.02-0.3] Total 59 3878 1.5 [1.2-2.0] RT accepted All result together Afraid of false positive result Official document Too recent high risk contact Not prepared to get the result today 5% 3% 2% 2% 1% 1457,87% 87% MSM SAM other 3% 17% 80% Kristien Wouters 1 , Katrien Fransen 1 , Greet Beelaert 1 , Chris Kenyon 1 , Tom Platteau 1 , Chris Van Ghyseghem 2 , Ilse Collier 2 , Jozefien Buyze 1 , Eric Florence 1 1 Institute of Tropical Medicine 2 Helpcenter ITG The use of Rapid HIV test in low threshold testing center is feasable and well accepted in Antwerp, Belgium, 2007-2012 P 5.024 - 16 July 2013 Contact: Kristien Wouters [email protected] Website: www.helpcenteritg.be or www.itg.be
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Page 1: The use of Rapid HIV test in low threshold testing center is … · Introduction Methods Results CONCLUSION The Antwerp Helpcenter (HC) is a low threshold center for HIV and STI testing

Introduction

Methods

Results

CONCLUSION

The Antwerp Helpcenter (HC) is a low threshold center for HIV and STI testing and dedicated to high risk groups: men having sex with men (MSM) and migrants from high endemic regions (mostly Sub Saharan African migrants, SAM). Rapid HIV tests (RT) are used at the HC for HIV screening since June 2007. The aim of this work is to describe our experience with this testing strategy.

A retrospective analysis of all Rapid Test routinely performed at HC. The Determine®HIV-1/2 (3th generation) was used as the RT until May 2009 and thereafter the Determine Combo®HIV-1/2 Ag/Ab (Alere) test (4th generation).All reactive tests were confirmed using INNO-LIA HIVI/II Score®. A validation study was performed on 310 samples at the beginning of the project.

By December 2012, 5025 Rapid Test had been performed on 3884 persons including 1209 MSM and 455 SAM migrants in the HelpcenterThe mean age of clients was 34 years. Tables 1-3, fig 1.The availability of RT was an important reason to consult at HC, 66% of the respondents highlight it as motivation to consult at HC. RT is of-fered to each person consulting at HC, 90% of them accepted to undergo a RT as screening for HIV. Figure 2.Of 59 confirmed new diagnoses, at least 50 were linked to care (84.75%).

• The overall prevalence of HIV infection in our test center was 1.5 %. In the two main target groups the prevalence was much higher: MSM 3,9% and SAM 2,2%• At least 85% of new diagnoses made with RT were successfully linked to care. • The relatively high proportion of positive RTs that were found to be HIV negative on confirmatory testing (12%) should act as reminder of the importance of adequate counseling and confirmatory strategy when using these rapid tests.

• The HIV Rapid Test was well accepted in a dedicated testing center and attracted many people to get tested. It is cheap, has a fast turnaround time and is easy to perform. • It can be used in VCT centers were people at higher risk are attracted (e.g. services aimed at MSM, migrants from high endemic regions, commercial sex workers, injecting drug users). • It is of particular utility in settings where there is a high risk that the client will not return for the result.

Rapid tests Number %

Total RT performed 5025 100 Positive 74 1.5Negative 4945 98.4Not interpretable 6 0,1

Table 1: Results of the RapidTests Table 2: Results of the confirmatory tests

Figure 1: New HIV diagnoses in risk groups Figure 2: Acceptance of RT

Table 3: New HIV diagnoses in risk groupsConfirmation test Number %

Total RT performed 74 100Confirmation positive 58 78.4

Confirmation indeterminate, 1 1,4antigen positive

Confirmation negative 9 12,2Already confirmed before 6 8.1

Risk group HIV+ Total % of tests in 95% Conf. risk group IntervalMSM 47 1209 3.9 [2.9-5.1]SAM 10 449 2.2 [1.2-4.1]other 2 2220 0.09 [0.02-0.3]Total 59 3878 1.5 [1.2-2.0]

RT accepted

All result together

Afraid of false positive result

Official document

Too recent high risk contact

Not prepared to getthe result today

5%

3%2% 2% 1%

1457,87%87%

MSM

SAM

other

3%

17%

80%

Kristien Wouters1, Katrien Fransen1, Greet Beelaert1, Chris Kenyon1, Tom Platteau1, Chris Van Ghyseghem2, Ilse Collier2, Jozefien Buyze1, Eric Florence1

1 Institute of Tropical Medicine 2 Helpcenter ITG

The use of Rapid HIV test in low threshold testing center is feasable and well accepted in Antwerp, Belgium, 2007-2012

P 5.024 - 16 July 2013

Contact: Kristien Wouters [email protected]: www.helpcenteritg.be or www.itg.be

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