Tissue solutions presentation march 2011

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Tissue

Working with you, for you…

Solutions

Your Virtual Bio Bankfor Drug & Biomarker Discovery

and Safety Testing

“We accurately determine your tissue needs to ensure we source the best tissues for your application.”


Tissue


Solutions

A New Approach Your Tissue Acquisition Team

What we do

Our Ethics

Types of Tissues

Network of Sources

Key advantages of working with us

Case Studies

“Working with specialist banks allows access to detailed donor information and in-house technical expertise.”


Tissue


Solutions

We are YOUR Acquisition Team YOU tell us what you need

WE find what you require

YOU save time

YOU save money

YOU focus on your research

YOU DO WHAT YOU DO BEST!

“Our focus is on our clients: by understanding your specific scientific needs we find the right samples to ask the right questions”


Tissue


Solutions

Procurement of Human Tissues and other Biological Materials

Mostly Pre-clinical Research

The right material for the right experiment

Delivered in a timely fashion

Using a large network of sources worldwide

What we do

“…we work with a virtual model where we source ethically acquired and fully consented quality human tissue from our network of source world-wide.”


Tissue


Solutions

Observing High Ethical Standards

Anonymous or de-identified donors

With Consent

Vetted prior to collaboration

Respect and dignity for tissues, samples & donors

Right to high quality medical care is the priority

Our Ethics

“We can supply surgical excess and post mortem tissues from donors with different conditions…”


Tissue


Solutions

Oncology

Autoimmune Disorders

CNS

Inflammation

Metabolic Disorders

Disease Areas Cardiovascular

Infectious Disorders

Blood Disorders

Control Samples (non-diseased, e.g. FDA panel)

“…we can carry out a prospective collection for you either in the UK, Russia or the

US.”


Tissue


Solutions

Special collections: custom procurement Fresh Surgical excess or post mortem Biopsies Other biomaterials (blood, urine,

CSF, etc.)

Routine Samples

Frozen (flash frozen or in OCT)

FFPE

Matched pairs (cancer plus NAT)

Detailed clinical annotations

Long term follow up data

Low ischemia time

Purified epithelial cell isolates

Types of Tissues

“We offer a range of tissue processing and analysis

services through our collaborating partners.”


Tissue


Solutions

• UK: NHS (university) hospitals, existing Tissue Banks

• Europe: commercial and not for profit banks

• USA:

hospitals

commercial bio banks

non commercial tissue banks

organ donor programs

• Other countries

Network of Sources

“We aim to free up your time time so you can do what you do best!”


Tissue


Solutions

Not a “catalogue” shop: customised to your needs

Wide network of sources: can deliver large orders quickly

We don’t shy away from difficult projects: fresh & rare tissues, e.g. DRGs, psoriasis

Scientific & intellectual input: collaborations, prospective collections

Full commercial rights to all samples

Compliant with the highest international ethical requirements

Why work with Tissue Solutions?

“Tissue Solutions is always looking for opportunities to add to its network of sources and collaborators.”


Tissue


Solutions

Shift towards fresh tissueTumours and /or Bloods/PBMCs Pancreatic, prostate, head & neck, glioblastoma, melanoma

Inflammatory TissuesPsoriasis skinRA bloods & synoviumAsthma/COPD lung

Less invasive biomaterialsUrineSalivaHair Follicles

Psoriatic skin

“Solid Ethics underpin our work at Tissue Solutions.”


Tissue


Solutions

Normal/Control Samples• Fresh normal tissues (NAT) – lung, liver etc• Whole bloods, Cord Blood, PBMCs• Bone Marrow• Skin – breast, abdomen, scalp, foreskin• CNS material eg DRGs

Shift towards fresh tissue

Fresh abdominal skin

Cord Blood Dorsal Root Ganglion

“…over 25 years of combined experience in the biotech and pharmaceutical industry in business development, project design & management and client relations.”


Tissue


Solutions

Applications of fresh tissue

Examples:• Cell Based Assays (FACs etc)• Primary Cell Establishment• Xenograph Studies, etc

“All donors who have graciously provided the material for research are key to progressing medical research.”


Tissue


Solutions

Donor InformationValue of tissue = donor information

Basics – age, sex, disease confirmation, staging etc+ race, medications, co-morbidities, lab results

Viral testing – HIV, HepB, HepC etc

Demand for follow-up data (years)

“Our focus is on our clients: by understanding your specific needs we find the right samples to ask the right research questions.”


Tissue


Solutions

• Pancreatic islets

• Hepatocytes: fresh / cryo-preserved,

• PBMC’s• Primary cells: Human Keratinocytes, Fibroblasts, Melanocytes, (Pre)-adipocytes, Monocytes, Lymphocytes, CD34+, Astrocytes, etc. Custom-made cell lines• GLP or non-GLP cross-reactivity studies (human and other species)• Bio-informatics support for Biomarker Identification

Additional Products and Services

“Working with our vast network of both post mortem and surgical excess sources, we supply ethically acquired and fully consented quality human tissue for research.”


Tissue


Solutions

Stand by our products:

• We guarantee quality

• We replace or refund material not fit for purpose

• All sources vetted: IRB or Ethics Committee approval for collecting human material Written consent of donors

Follow up on customer satisfaction

Repeat business is important (~ 80 %)

Quality

“We provide a range of fresh human tissue samples to our clients in the UK, US and Europe on a prospective basis.”


Tissue


Solutions

Thank you for your time! Come and visit us in Glasgow.

Ann Cooreman, PhD

[email protected]

+44 (0)141 951 7885

Date post:	07-Dec-2014
Category:	Health & Medicine
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Tissue solutions presentation march 2011

Health & Medicine