LIST OF CONTENTS

V O L U M E 69 N U M B E R 1

COMMENTARY J.-C. Cassel and H. Jeltsch Serotonergic modulation of cholinergic function in the

central nervous system: cognitive implications

RESEARCH PAPERS M. Levivier, D. M. Gash and S. Przedborski

Time course of the neuroprotective effect of transplantation on quinolinic acid-induced lesions of the striatum

I. A. Shevelev, R. V. Novikova, N. A. Lazareva, A. S. Tikhomirov and G. A. Sharaev

Sensitivity to cross-like figures in the cat striate neurons

T. C. Napier, I. Mitrovic, L. Churchill, M. A. Kiitenick, X.-Y. Lu and P. W. Kalivas

Substance P in the ventral pallidum: projection from the ventral striatum, and electrophysiological and behavioral consequences of pallidal substance P

P.-Y. C6t~, P. Levitt and A. Parent Distribution of limbic system-associated membrane protein immunoreactivity in primate basal ganglia

A. M. Magarifios and B. S. McEwen Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: comparison of stressors

A. M. Magarifios and B. S. McEwen Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: involvement of gluco- corticoid secretion and excitatory amino acid receptors

E. Cs. Papp, B. Heimrich and T. F. Freund

Development of the raphe-hippocampal projection in vitro

G. D. Rosen, E. A. Sigel, G. F. Sherman and A. M. Galaburda

The neuroprotective effects of MK-801 on the induction of microgyria by freezing injury to the newborn rat neocortex

Y. S. Mednikova and S. V. Karnup Functional geometry of amino acid sensitive membrane of layer V neurons in the guinea-pig neocortex in vitro

A. F. Greenwood, R. E. Powers and R. S. Jope

Phosphoinositide hydrolysis, G~q, phospholipase C, and protein kinase C inpos t mortem human brain: effects of post mortem interval, subject age, and Alzheimer's disease

I. Mody, T. S. Otis, A. Bragin, M. Hsu and G. Buzsfiki

GABAergic inhibition of granule cells and hilar neuronal synchrony following ischemia-induced hilar neuronal loss

L. Korbo and B. B. Andersen The distributions of Purkinje cell perikaryon and nuclear volume in human and rat cerebellum with the nucleator method

D. Guivarc'h, P. Vernier and J.-D. Vincent

Sex steroid hormones change the differential distribution of the isoforms of the D 2 dopamine receptor messenger RNA in the rat brain

J. M. Kinzie, J. A. Saugstad, G. L. Westbrook and T. P. Segerson

Distribution of metabotropic glutamate receptor 7 messenger RNA in the developing and adult rat brain

B. Chamak, A. Dobbertin and M. Mallat Immunohistochemical detection of thrombospondin in microglia in the developing rat brain

iii

1995

43

51

59

71

83

89

99

107

115

125

139

151

159

167

177

M. Haj6s, S. E. Gartside, A. E. P. Villa and T. Sharp

J. M. Mahon, M. Allen, J. Herbert and J. T. Fitzsimons

L. H. Conti and S. L. Foote

S. Boehm and S. Huck

B. A. Morrow, J. R. Taylor and R. H. Roth

A. K. Houghton, C. M. F. Gorringe and R. W. Clarke

C. Dean and J. L. Seagard

Y. Charnay, L. Leger, P. G. Vallet, P. R. Hof, M. Jouvet and C. Bouras

M. I. Glavinovi~

W. E. Crowe, J. Aitamirano, L. Huerto and F. J. Alvarez-Leefmans

Z.-Y. Wang, P. Aim and R. H~kanson

S. Liu and R. H. Nordlander

J. Kucera, P. Ernfors, J. Walro and R. Jaenisch

A. Golard

Evidence for a repetitive (burst) firing pattern in a sub-population of 5-hydroxytryptamine neurons in the dorsal and median raphe nuclei of the rat

The association of thirst, sodium appetite and vasopressin release with c-[bs expression in the forebrain of the rat after intracerebroventricular injection of angiotensin II, angiotensin-(l-7) or carbachol

Effects of pretreatment with corticotropin-releasing factor on the electrophysiological responsivity of the locus coeruleus to subsequent corticotropin-releasing factor challenge

~2-Adrenoreceptor-mediated inhibition of acetylcholine- induced noradrenaline release from rat sympathetic neurons: an action at voltage-gated Ca ̀ ,+ channels

Prior exposure to cocaine diminishes behavioral and biochemical responses to aversive conditioning: reversal by glycine/N-methyl-D-aspartate antagonist co-treatment

Tachykininergic tone in the spinal cord of the rabbit: dependence on nociceptive input arising from invasive surgery

Expression of c-Jos protein in the nucleus tractus solitarius in response to physiological activation of carotid baroreceptors

[3H]Nisoxetine binding sites in the cat brain: an autoradiographic study

Decrease of quantal size and quantal content during tetanic stimulation detected by focal recording

Volume changes in single NlE-115 neuroblastoma cells measured with a fluorescent probe

Distribution and effects of pituitary adenylate cyclase- activating peptide in the rabbit eye

Growth cones and axon trajectories of the earliest descending serotonergic pathway of Xenopus

Reduction in the number of spinal motor neurons in neurotrophin-3-deficient mice

Lectins modulate calcium channels in chick sympathetic ganglia

189

199

209

221

233

24t

249

259

271

283

297

309

321

331

V O L U M E 69 N U M B E R 2

LETTERS TO NEUROSCIENCE S. L. Eastwood and P. J. Harrison

N. C. Gordon, R. W. Gear, P. H. Heller, S. Paul, C. Miaskowski and J. D. Levine

RESEARCH PAPERS E. C. Bargard and J. J. Hahlitz

1995

Decreased synaptophysin in the medial temporal lobe in 339 schizophrenia demonstrated using immunoautoradio- graphy

Enhancement of morphine analgesia by the GABA~ 345 agonist baclofen

N-Methyl-o-aspartate receptor-mediated calcium accumulation in neocortical neurons

351

J. J. O'Connor, J. Wu, M. J. Rowan and R. Anwyl

Potentiation of N-methyl-D-aspartate-receptor-medi- ated currents detected using the excised patch technique in the hippocampal dentate gyrus

363

C. L. Miller and R. Freedman The activity of hippocampal interneurons and pyramidal cells during the response of the hippocampus to repeated auditory stimuli

371

K. W. Roche and R. L. Huganir Synaptic expression of the high-affinity kainate receptor subunit KA2 in hippocampal cultures

383

J. E. Madl and D. L. Allen Hyperthermia depletes adenosine triphosphate and decreases glutamate uptake in rat hippocampal slices

395

A. K. Shetty, D. Rapoza, R. D. Madison and D. A. Turner

Selective laser-activated lesioning of prelabeled fetal hippocampal grafts by intracellular photolytic chromophore

407

M. E. Wolf, S. L. Dahlin, X.-T. Hu, C.-J. Xoe and K. White

Effects of lesions of prefrontal cortex, amygdala, or fornix on behavioral sensitization to amphetamine: comparison with N-methyl-o-aspartate antagonists

417

J. N. Simpson, J. Q. Wang and J. F. McGinty

Repeated amphetamine administration induces a prolonged augmentation of phosphorylated cyclase response element-binding protein and Fos-related antigen immunoreactivity in rat striatum

441

W. Du, A. G. Romano, V. J. Aioyo and J. A. Harvey

Hypotensive stress retards associative learning in rabbits 459

R. Drake-Baumann and F. J. Seil Electrophysiological differences between Purkinje cells in organotypic and granuloprival cerebellar cultures

467

E. Kumamoto and Y. Murata Excitatory amino acid-induced currents in rat septal cholinergic neurons in culture

477

A. Khateb, P. Fort, A. Pegna, B. E. Jones and M. Miihlethaler

Cholinergic nucleus basalis neurons are excited by histamine in vitro

495

G. M. Krauthamer, B. S. Grunwerg and H. Krein

Putative cholinergic neurons of the pedunculopontine tegmental nucleus projecting to the superior colliculus consist of sensory responsive and unresponsive popu- lations which are functionally distinct from other mesopontine neurons

507

J. A. Chowen, S. Busiguina and L. M. Garcia-Segura

Sexual dimorphism and sex steroid modulation of glial fibrillary acidic protein messenger RNA and immuno- reactivity levels in the rat hypothalamus

519

G. V. Allen and D. F. Cechetto Neurotensin in the lateral hypothalamic area: origin and function

533

S. Amir, B. Robinson and K. Edelstein Distribution of NADPH-diaphorase staining and light- induced Fos expression in the rat suprachiasmatic nucleus region supports a role for nitric oxide in the circadian system

545

M. Pasic and G. Kartelija The reaction of Helix photosensitive neurons to light and cyclic GMP

557

D. Park, Y. Smith and J.-F. Park Intra-amygdaloid projections of the basolateral and basomedial nuclei in the cat: Phaseolus vulgaris-leuco- agglutinin anterograde tracing at the light and electron microscopic level

567

H. Nakazawa, H. Kaha, T. Higuehi The importance of calmodulin in the accessory olfactory 585 and S. Inoue bulb in the formation of an olfactory memory in mice

N. C. Hall, J. M. Carney, M. Cheng and D. A. Butterfield

J. Lipski, R. Kanjhan, B. Kruszewska and M. Smith

E. A. J. Joosten, P. R. Bfir and W.-H. Gispen

S. Diochot, S. Richard and J. Valmier

V. Zagorodnyuk and C. A. Maggi

H. lnokuchi and E. M. MeLachlan

V. V. MarHnsky

M. R. Hayman, J. P. Donaldson and I. M. L. Donaldson

S. G. Khasar, F. J.-P. Miao and J. D. Levine

Prevention of ischemia/reperfusion-induced alterations in synaptosomal membrane-associated proteins and lipids by N-tert-butyl-ct-phenylnitrone and difluoro- methylornithine

Barosensitive neurons in the rostral ventrolateral medulla of the rat in vivo : morphological properties and relationship to CI adrenergic neurons

Directional regrowth of lesioned corticospinal tract axons in adult rat spinal cord

Diversity of voltage-gated calcium currents in large diameter embryonic mouse sensory neurons

Neuronal tachykinin NK 2 receptors mediate release of non-adrenergic non-cholinergic inhibitory transmitters in the circular muscle of guinea-pig colon

Lack of evidence for P2X-purinoceptor involvement in fast synaptic responses in intact sympathetic ganglia isolated from guinea-pigs

The effect of somatosensory stimulation on second- order and efferent vestibular neurons in the decerebrate decerebellate guinea-pig

The primary afferent pathway of extraocular muscle proprioception in the pigeon

Inflammation modulates the contribution of receptor- subtypes to bradykinin-induced hyperalgesia in the rat

591

601

619

627

643

651

661

671

685

V O L U M E 69 N U M B E R 3

LETTERS TO NEUROSCIENCE T. Arendt, M. Holzer, R. Frnth, M. K. Briiekner and U. Girtner

C. L. Boulton, E. Southam and J. Garthwaite

C. Schwarzer and G. Sperk

COMMENTARY L. F. Agnati, M. Zoli, I. Str/imMrg and K. Fnxe

RESEARCH PAPERS A. M. Thomson, D. C. West and J. Deuchars

J. Deuchars and A. M. Thomson

Paired helical filament-like phosphorylation of tau, deposition of fl/A4-amyloid and memory impairment in rat induced by chronic inhibition of phosphatase 1 and 2A

Nitric oxide-dependent long-term potentiation is blocked by a specific inhibitor of soluble guanylyl cyclase

Hippocampal granule cells express glutamic acid decarboxylase-67 after limbic seizures in the rat

Intercellular communication in the brain: wiring versus volume transmission

Properties of single axon excitatory postsynaptic poten- tials elicited in spiny interneurons by action potentials in pyramidal neurons in slices of rat neocortex

Innervation of burst firing spiny interneurons by pyramidal cells in deep layers of rat somatomotor cortex: paired intracellular recordings with biocytin filling

1995

691

699

705

711

727

739

Zs. Nagy, M. M. Esiri, K. A. Jobst, C. Johnston, S. Litchfield, E. Sim and A. D. Smith

Influence of the apolipoprotein E genotype on amyloid deposition and neurofibrillary tangle formation in Alzheimer's disease

757

M. N. Patel and J. O. McNamara Selective enhancement of axonal branching of cultured dentate gyrus neurons by neurotrophic factors

763

K. A. Huber, K. Krieglstein and K. Unsicker

K. Andreasson and P. F. Worley

The neurotrophins BDNF, NT-3 and -4, but not NGF, TGF-fl 1 and GDNF, increase the number of NADPH- diaphorase-reactive neurons in rat spinal cord cultures

Induction of fl-A activin expression by synaptic activity and during neocortical development

771

781

V. Moro, J. Badaut, V. Springhetti, L. Edvinsson, J. Seylaz and F. Lasbennes

Regional study of the co-localization of neuronal nitric oxide synthase with muscarinic receptors in the rat cerebral cortex

797

A. Bessis, A.-M. Salmon, M. Zoli, N. Le Nov6re, M. Picciotto and J.-P. Changeux

Promoter elements conferring neuron-specific expression of the/~ 2-subunit of the neuronal nicotinic acetylcholine receptor studied in vitro and in transgenic mice

807

X. O. Zhu, M. W. Brown, B. J. McCabe and J. P. Aggleton

Effects of the novelty or familiarity of visual stimuli on the expression of the immediate early gene c-fos in rat brain

821

C. Schwarzer, J. M. Williamson, E. W. Lothman, A. Vezzani and G. Sperk

Somatostatin, neuropeptide Y, neurokinin B and chole- cystokinin immunoreactivity in two chronic models of temporal lobe epilepsy

831

L. Van Bree, F. Zhang, S. N. Schiffmann, P. Halleux, P. Mailleux and J.-J. Vanderhaeghen

Homolateral cerebrocortical changes in neuropeptide and receptor expression after minimal cortical infarction

847

B. S. Kolachana, R. C. Saunders and D. R. Weinberger

Augmentation of prefrontal cortical monoaminergic activity inhibits dopamine release in the caudate nucleus: an in vivo neurochemical assessment in the rhesus monkey

859

T. Oyama, S. Goto, T. Nishi, K. Sato, K. Yamada, M. Yoshikawa and Y. Ushio

Immunocytochemical localization of the striatal enriched protein tyrosine phosphatase in the rat striatum: a light and electron microscopic study with a complementary DNA-generated polyclonal antibody

869

S. Kroesen, J. Marksteiner, S. K. Mahata, M. Mahata, R. Fischer-Colbrie, A. Saria, I. Kapeller and H. Winkler

Effects of haloperidol, clozapine and citalopram on messenger RNA levels of chromogranins A and B and secretogranin II in various regions of rat brain

881

T. F. Oo, C. Henchclitfe and R. E. Burke Apoptosis in substantia nigra following developmental hypoxic-ischemic injury

893

C. E. Rick, I. M. Stanford and M. G. Lacey

Excitation of rat substantia nigra pars reticulata neurons by 5-hydroxytryptamine in vitro: evidence for a direct action mediated by 5-hydroxytryptamine2c receptors

903

I. B. Walsh, R. J. van den Berg and W. J. Rietveld

Ionic currents in cultured rat suprachiasmatic neurons 915

D. Bouhassira, D. Chitour, L. Villanueva and D. Le Bars

The spinal transmission of nociceptive information: modulation by the caudal medulla

931

E. Carstens, I. Saxe and R. Ralph Brainstem neurons expressing c-Fos immunoreactivity following irritant chemical stimulation of the rat's tongue

939

vii

S. Quasthoff, J. Grosskreutz, J. M. Schr6der, U. Schneider and P. Grafe

M.-F. Vesin, C. Billotte and B. Droz

S. A. Waterman and C. A. Maggi

A. Meulemans, J. P. Mothet, A. Schirar, P. Fossier, L. Tauc and G. Baux

I. Neumann, P. Kremarik and Q. J. Pittman

Calcium potentials and tetrodotoxin-resistant sodium potentials in unmyelinated C fibres of biopsied human sural nerve

Biosynthesis of prostaglandin D 2 by motoneurons and dorsal horn microneurons: a biochemical and high resol- ution immunocytochemical study in chick spinal cord

Stimulation of neuropeptide release from sensory and enteric neurons in the guinea-pig by ~-latrotoxin

A nitric oxide synthase activity is involved in the modulation of acetylcholine release in Aplysia ganglion neurons: a histological, voltammetric and electrophysio- logical study

Acute, sequence-specific effects of oxytocin and vasopressin antisense oligonucleotides on neuronal responses

955

967

977

985

997

V O L U M E 69 N U M B E R 4

LETTERS TO NEUROSCIENCE I. Neumann, P. Kremarik and Q. J. Pittman

S. Amir and B. Robinson

G. Crosby, J. J. A. Marota and P. L. Huang

,~. Dagerlind, M. Pelto-Huikko, M. Diez and T. H6kfelt

H. I. Kornblum, C. M. Gall, K. B. Seroogy and J. C. Lauterborn

RESEARCH PAPERS A. Baude, Z. Nusser, E. MoinAr, R. A. J. Mcllhinney and P. Somogyi

R. Khazipov, D. Ragozzino and P. Bregestovski

A. I. Hersi, W. Rowe, P. Gaudreau and R. Quirion

P. A. Brennan, K. M. Kendrick and E. B. Keverne

C. Sandi, S. P. R. Rose, R. Mileusnic and C. Lancashire

A. R. Guimaraes, P. Schwartz, M. R. Prakash, C. A. Carr, U. V. Berger, B. G. Jenkins, J. T. Coyle and R. G. Gonz~lez

1995

Acute, sequence-specific effects of oxytocin and 997 vasopressin antisense oligonucleotides on neuronal responses

Ultraviolet light entrains rodent suprachiasmatic nucleus 1005 pacemaker

Intact nociception-induced neuroplasticity in transgenic 1013 mice deficient in neuronal nitric oxide synthase

Adrenal medullary ganglion neurons project into the 1019 splanchnic nerve

A subpopulation of striatal GABAergic neurons 1025 expresses the epidermal growth factor receptor

High-resolution immunogold localization of AMPA type glutamate receptor subunits at synaptic and non- synaptic sites in rat hippocampus

Kinetics and Mg =+ block of N-methyl-D-aspartate receptor channels during postnatal development of hippocampal CA3 pyramidal neurons

Dopamine D I receptor ligands modulate cognitive performance and hippocampal acetylcholine release in memory-impaired aged rats

Neurotransmitter release in the accessory olfactory bulb during and after the formation of an olfactory memory in mice

Corticosterone facilitates long-term memory formation via enhanced glycoprotein synthesis

Quantitative in vivo ~H nuclear magnetic resonance spectroscopic imaging of neuronal loss in rat brain

viii

1031

1057

1067

1075

1087

1095

R. Carletti, S. Tacconi, E. Bettini and F. Ferraguti

I. Ferrer and A. M. Planas

J. M. Elliott, N. R. Newberry, A. J. Cholewinski, J. T. Bartrup, S. J. Briddon, J. E. Carey, T. P. Fianigan, R. A. Newton, S. L. Phipps, A. C. Reavley, C. Smith, M. Wigmore, D. G. Grahame-Smith and R. A. Leslie

Y. Bozzi, T. Pizzorusso, F. Cremisi, F. M. Rossi, G. Barsacchi and L. Maffei

K.-M. Kim, Y. Nak~ima and S. Nak~ima

S. Patel, J. Roberts, J. Moorman and C. Reavill

M. Olsson, K. Campbell, K. Wictorin and A. Bj6rklund

L. Danober, A. Depaulis, M. Vergnes and C. Marescaux

F. Zhang, S. Xu and C. ladecola

Z. Szeidemann, R. L. Jakab, M. Shanabrough and C. Leranth

J. M. Hilton, S. Y. Chai and P. M. Sexton

O. J. Igwe and M. B. Filla

C. Stapf, M. Shakibaei and D. Blottner

V. S. Seybold and L. G. Abrahams

F. A. van Golen, K. W. Li, R. P. J. De Lange, R. E. Van Kesteren, R. C. Van Der Schors and W. P. M. Geraerts

Stress activated protein kinases, a novel family of mitogen-activated protein kinases, are heterogeneously expressed in the adult rat brain and differentially distributed from extracellular-signal-regulated protein kinases

Induction of heat-shock protein-70 messenger RNA and protein following systemic kainate injection in the rat: evidence of protein axonal transport

Characterization of the 5-hydroxytryptamine2A receptor- activated cascade in rat C6 glioma cells

Monocular deprivation decreases the expression of messenger RNA for brain-derived neurotrophic factor in the rat visual cortex

G protein-coupled inward rectifier modulated by dopamine agonists in cultured substantia nigra neurons

Localization of serotonin-4 receptors in the striatonigral pathway in rat brain

Projection neurons in fetal striatal transplants are predominantly derived from the lateral ganglionic eminence

Mesopontine cholinergic control over generalized non-convulsive seizures in a genetic model of absence epilepsy in the rat

Role of nitric oxide and acetylcholine in neocortical hyperemia elicited by basal forebrain stimulation: evidence for an involvement of endothelial nitric oxide

Extrinsic and intrinsic substance P innervation of the rat lateral septal area calbindin cells

In vitro autoradiographic localization of the calcitonin receptor isoforms, Cla and Clb, in rat brain

Regulation of phosphatidylinositide transduction system in the rat spinal cord during aging

Co-existence of NADPH-diaphorase, fibroblast growth factor-2 and fibroblast growth factor receptor in spinal autonomic system suggests target-specific actions

Characterization and regulation of neurokinin, receptors in primary cultures of rat neonatal spinal neurons

Co-localized neuropeptides conopressin and Ala -Pro- G ly -Trp -NH 2 have antagonistic effects on the vas deferens of lymnaea

1103

1111

1119

1133

1145

1159

1169

1183

1195

1205

1223

1239

1253

1263

1275

AUTHOR INDEX

Abrahams L. G., 1263 Aggleton J. P., 821 Agnati L. F., 711 Allen D. L., 395 Allen G. V., 533 Allen M., 199 Aim P., 297 Aloyo V. J., 459 Altamirano J., 283 Alvarez-Leefmans F. J., 283 Amir S., 545, 1005 Andersen B. B., 151 Andreasson K., 781 Anwyl R., 363 Arendt T., 691

Badaut J., 797 B~ir P. R., 619 Bars D. L., 931 Barsacchi G., 1133 Bartrup J. T., 1119 Baude A., 1031 Baux G., 985 Berger U. V., 1095 Bessis A., 807 Bettini E., 1103 Billotte C., 967 Bj6rklund A., 1169 Blottner D., 1253 Boehm S., 221 Bouhassira D., 93l Boulton C. L., 699 Bouras C., 259 Bozzi Y., 1133 Bragin A., 139 van Bree L., 847 Bregestovski P., 1057 Brennan P. A., 1075 Briddon S. J., 1119 Brown M. W., 821 Briickner M. K., 691 Burgard E. C.. 351 Burke R. E., 893 Busiguina S., 519 Butterfield D. A., 591 Buzs~iki G., 139

Campbell K., 1169 Carey J. E., 1119 Carletti R., 1103 Carney J. M., 591 Carr C. A., 1095 Carstens E., 939 Cassel J.-C., 1 Cechetto D. F., 533 Chai S. Y., 1223 Chamak B., 177 Changeux J.-P., 807 Charnay Y., 259 Cheng M., 591 Chitour D., 931 Cholewinski A. J., 1119 Chowen J. A., 519 Churchill L., 59 Clarke R. W., 241 C6t~ P.-Y., 71 Conti L. H., 209 Coyle J. T., 1095 Cremisi F., 1133

Crosby G., 1013 Crowe W. E., 283

Dagerlind A., 1019 Dahlin S. L., 417 Danober L., 1183 De Lange R. P. J., 1275 Dean C., 249 Depaulis A., 1183 Deuchars J., 727, 739 Diez M., 1019 Diochot S., 627 Dobbertin A., 177 Donaldson I. M. L., 671 Donaldson J. P., 671 Drake-Baumann R., 467 Droz B., 967 Du W., 459

Eastwood S. L., 339 Edelstein K., 545 Edvinsson L., 797 Elliott J. M., l 119 Ernfors P., 321 Esiri M. M., 757

Ferraguti F., 1103 Ferrer I., 1111 Filla M. B., 1239 Fischer-Colbrie R., 881 Fitzsimons J. T., 199 Flanigan T. P., 1119 Foote S. L., 209 Fort P., 495 Fossier P., 985 Freedman R., 371 Freund T. F., 99 Fruth R., 691 Fuxe K., 711

Galaburda A. M., I07 Gall C. M., 1025 Garcia-Segura L. M., 519 Garthwaite J., 699 Gfirtner U., 691 Gartside S. E., 189 Gash D. M., 43 Gaudreau P., 1067 Gear R. W., 345 Geraerts W. P. M., 1275 Gispen W.-H., 619 Glavinovi6 M. I., 271 Golard A., 331 van Golen F. A., 1275 Gonzfilez R. G., 1095 Gordon N. C., 345 Gorringe C. M. F., 241 Goto S., 869 Grafe P., 955 Grahame-Smith D. G., 1119 Greenwood A. F., 125 Grosskreutz J., 955 Grunwerg B. S., 507 Guimaraes A. R., 1095 Guivarc'h D., 159

Hablitz J. J., 351 Haj6s M., 189 Hall N. C., 591

xi

Halleux P., 847 Harrison P. J., 339 Harvey J. A., 459 Hayman M. R., 671 H~kanson R., 297 Heimrich B., 99 Heller P. H., 345 Henchcliffe C., 893 Herbert J., 199 Hersi A. I., 1067 Higuchi T., 585 Hilton J. M., 1223 Hof P. R., 259 H6kfelt T., 1019 Holzer M., 691 Houghton A. K., 241 Hsu M., 139 Hu X.-T., 417 Huang P. L., 1013 Huber K. A., 771 Huck S., 221 Huerto L., 283 Huganir R. L., 383

ladecola C., 1195 lgwe O. J., 1239 Inokuchi H., 651 Inoue S., 585

Jaenisch R., 321 Jakab R. L., 1205 Jeltsch H., 1 Jenkins B. G., 1095 Jobst K. A., 757 Johnston C., 757 Jones B. E., 495 Joosten E. A. J., 619 Jope R. S., 125 Jouvet M., 259

Kaba H., 585 Kalivas P. W., 59 Kanjhan R., 601 Kapeller I., 881 Karnup S. V., 115 Kartelija G., 557 Kendrick K. M., 1075 Keverne E. B., 1075 Khasar S. G., 685 Khateb A., 495 Khazipov R., 1057 Kim K.-M., 1145 Kinzie J. M., 167 Klitenick M. A., 59 Kolachana B. S., 859 Korbo L., 151 Kornblum H. I., 1025 Krauthamer G. M., 507 Krein H., 507 Kremarik P., 997 Krieglstein K., 771 Kroesen S., 881 Kruszewska B., 601 Kucera J., 321 Kumamoto E., 477

Lacey M. G., 903 Lancashire C., 1087 Lasbennes F., 797

Lauterborn J. C., 1025 Lazareva N. A., 51 Leger L., 259 Leranth C., 1205 Leslie R. A., 1119 Levine J. D., 345, 685 Levitt P., 71 Levivier M., 43 Li K. W., 1275 Lipski J., 601 Litchfield S., 757 Liu S., 309 Lothman E. W., 831 Lu X.-Y., 59

Madison R. D., 407 Madl J. E., 395 Maffei L., 1133 Magarifios A. M., 83, 89 Maggi C. A., 643, 977 Mahata M., 881 Mahata S. K., 881 Mahon J. M., 199 Mailleux P., 847 Mallat M., 177 Marescaux C., 1183 Marksteiner J., 881 Marlinsky V. V., 661 Marota J. J. A., 1013 McCabe B. J., 821 McEwen B. S., 83, 89 McGinty J. F., 441 Mcllhinney R. A. J., 1031 McLachlan E. M., 651 McNamara J. O., 763 Mednikova Y. S., 115 Meulemans A., 985 Miao F. J.-P., 685 Miaskowski C., 345 Mileusnic R., 1087 Miller C. L., 371 Mitrovic I., 59 Mody I., 139 Moln~.r E., 1031 Moorman J., 1159 Moro V., 797 Morrow B. A., 233 Mothet J. P., 985 Mfihlethaler M., 495 Murata Y., 477

Nagy Zs., 757 Nakajima S., 1145 Nakajima Y., 1145 Nakazawa H., 585 Napier T. C., 59 Neumann I., 997 Newberry N. R., 1119 Newton R. A., 1119 Nishi T., 869 Nordlander R. H., 309 Nov6re N. L., 807 Novikova R. V., 51 Nusser Z., 1031

O'Connor J. J., 363 Olsson M., 1169 Oo T. F., 893

Otis T. S., 139 Oyama T., 869

Papp E. Cs., 99 Par6 D., 567 Par6 J.-F., 567 Parent A., 71 Pasic M., 557 Patel M. N., 763 Patel S., 1159 Paul S., 345 Pegna A., 495 Pelto-Huikko M., 1019 Phipps S. L., 1119 Picciotto M., 807 Pittman Q. J., 997 Pizzorusso T., 1133 Planas A. M., III 1 Powers R. E., 125 Prakash M. R., 1095 Przedborski S., 43

Quasthoff S., 955 Quirion R., 1067

Ragozzino D., 1057 Ralph R., 939 Rapoza D., 407 Reavill C., 1159 Reavley A. C., 1119 Richard S., 627 Rick C. E., 903 Rietveld W. J., 915 Roberts J., I 159 Robinson B., 545, 1005 Roche K. W., 383 Romano A. G., 459 Rose S. P. R., 1087 Rosen G. D., 107 Rossi F. M., 1133 Roth R. H., 233 Rowan M. J., 363 Rowe W., 1067

Salmon A.-M., 807 Sandi C., 1087 Saria A., 881 Sato K., 869 Saugstad J. A., 167 Saunders R. C., 859 Saxe I., 939 Schiffmann S. N., 847 Schirar A., 985 Schneider U., 955 Schr6der J. M., 955 Schwartz P., 1095 Schwarzer C., 705, 831 Seagard J. L., 249 Segerson T. P., 167 Seil F. J., 467 Seroogy K. B., 1025 Sexton P. M., 1223 Seybold V. S., 1263 Seylaz J., 797 Shakibaei M., 1253 Shanabrough M., 1205 Sharaev G. A., 51 Sharp T., 1-89 Sherman G. F., 107

Shetty A. K., 407 Shevelev I. A., 51 Sigel E. A., 107 Sim E., 757 Simpson J. N., 441 Smith A. D., 757 Smith C., 1119 Smith M., 601 Smith Y., 567 Somogyi P., 1031 Southam E., 699 Sperk G., 705, 831 Springhetti V., 797 Stanford I. M., 903 Stapf C., 1253 Str6mberg I., 711 Szeidemann Z., 1205

Tacconi S., 1103 Tauc L., 985 Taylor J. R., 233 Thomson A. M., 727, 739 Tikhomirov A. S., 51 Turner D. A., 407

Unsicker K., 771 Ushio Y., 869

Vallet P. G., 259 Valmier J., 627 Van Den Berg R. J., 915 Van Der Schors R. C., 1275 Van Kesteren R. E., 1275 Vanderhaeghen J.-J., 847 Vergnes M., 1183 Vernier P., 159 Vesin M.-F., 967 Vezzani A., 831 Villa A. E. P., 189 Villanueva L., 931 Vincent J.-D., 159

Walro J., 321 Walsh I. B., 915 Wang J. Q., 441 Wang Z.-Y., 297 Waterman S. A., 977 Weinberger D. R., 859 West D. C., 727 Westbrook G. L., 167 White K., 417 Wictorin K., 1169 Wigmore M., 1119 Williamson J. M., 831 Winkler H., 881 Wolf M. E., 417 Worley P. F., 781 Wu J., 363

Xu S., 1195 Xue C.-J., 417

Yamada K., 869 Yoshikawa M., 869

Zagorodnyuk V., 643 Zhang F., 847, 1195 Zhu X. O., 821 Zoli M., ? 11 Zoli M., 807

xii

KEY WORD INDEX

a,3-methylene ATP, 651 4-amino-pyridine, 915 5-HT4-receptor autoradiography, 1159 5-hydroxytryptamine, 1,309 6-hydroxydopamine, 1159 Acetylcholine, 1183, 1205 Adenosine A2 receptors, 43 Adrenal gland, 1253 Aging process, 1239 Aging, 125, 1067 Alpha-toxin, 283 Alzheimer's disease, 691 Amino acids, 115 Ammon's horn, 83, 89 AMPA receptors, 89 AMPA receptor, 383 AMPA, 477 Amphetamine, 859 Amphibian embryo, 309 Amygdala, 533,567 Amylin, 1223 Anesthesia, 1013 Angiotensin peptides, 199 Animal model, 691 Antidromic activation, 507 Antipsychotics, 881 AP-1, 441 Arcuate nucleus, 519 Arousal, 495 Astrocytes, 519 Atropine, 1195 Auditory pathways, 371 Autonomic motor neurons, 1253 Autonomic, 977 Autoradiography, 259 Axon, 763 Axonal growth, 177 Axotomy, 1019

Baroreceptor reflex, 249 Baroreceptors, 249 Basic fibroblast growth factor, 763 Basal forebrain, 495 Basal ganglia, 869, 903 Behavioral sensitization, 441 Bicuculline, 1133 Bioassay, 1275 Biocytin, 739 Black widow spider venom, 977 Blood pressure, 459 Brain, 591, 1025 Brain slices, 9903

C-fibres, 297 c-fos immunohistochemistry, 249 Ca 2+ , 1119 Calcein, 283 Calcitonin gene-related peptide, 297 Calcium, 283,727

Calcium channels, 627 Calmidazolium, 585 Capsaicin, 939,955 Carbachol, 199 Cardiovascular, 533 Caudate, 1025 CCKb receptor, 847 Cell volume, 151,283 Cell permeabilization, 283 Central cardiovascular control, 601 Central nervous system, 711, 967, 1103, 1253 Central sensitization, 1013 Cerebellum, 467 Cerebral circulation, 1195 Cerebral cortex, 107, 1025 Cerebral vessels, 797 Channels, 1057 Chemical shift imaging, 1095 Chick, 1087 Chlorines, 407 Cholecystokinin, 847 Choline acetyltransferase immunocytochemistry, 1159 Cholinergic, 125 Circadian rhythms, 545, 1005 Classical conditioning, 459 Co-localization, 1205 Co-transmitters, 1275 Cocaine, 859 Collagen, 619 Complex spikes, 467 Concanavalin A, 331 Confocal microscopy, 797 Conotoxin, 955 Copulation behaviour, 1275 Corpus callosum, 177 Cortex, 1, 847 Cortical circuitry, 739 Cortical plasticity, 1133 Cortical plate, 781 Corticosterone, 83, 89, 459 CRF antagonist, 209 Critical period, 1133 Cultured neurons, 915 Cyanoketone, 89 Cyclic GMP, 699 Cyclic AMP, 1145 Cytochrome c oxidase, 43 Cytosine arabinoside, 467

DARPP-32, 1169 Dendrite, 763 Dendrites, 115 Dental pain, 345 Dentate gyms, 139, 831 Depression, 209 Descending controls, 931 Desensitization, 209, 1119

Development, 107, 177,519 Differentiation, 771, 1119 DiffusiOn, 711 Dopamine, 233 Dopamine D1 receptor, 43 Dopaminergic, 893 Dorsal medulla, 249 Dorsal raphe nucleus, 189 Dorsal root ganglion, 627 Double immunostaining, 1205 Down-regulation, 1119 Drinking behaviour, 199

E-box, 807 Electrical field stimulation, 221 Electron microscopy, 567,739,967 Electron paramagnetic resonance, 591 Electrophysiology, 189,209,903 Embryonic tissue graft, 1169 Energy depletion, 395 Enteric nervous system, 643 Epilepsy, 139,705 ERK, 1103 Estradiol, 159 Excitation, 1031 Excitatory amino acids, 417 Excitatory postsynaptic currents, 363 Excitotoxic cell injury, 1095 Excitotoxicity, 43 Exocytosis, 977 External cuneate nucleus, 671 Extracellular fluid, 711 Eye muscle, 671

Fast excitatory synaptic current, 651 Fast excitatory synaptic potential, 651 Fear, 233 Fear conditioning, 567 Feline brain, 259 Fever, 395 FK 506, 585 Flexor reflex afferents, 661 FluoroGold, 533 Fos, 997, 1005 Fos-like immunoreactivity, 249 Free radicals, 591 Fucosylation, 1087 Fusimotor neurons, 321

G-protein, 125 G-proteins, 159,331 G-protein-coupled receptor, 1223 GABA, 99, 139, 705,903, 1205 Galanin, 1019 Gasserian ganglion, 671 Gender, 345 Gene expression, 997 Genotype, 757 Gerbil, 591

xiii

Glia, 519 Globus pallidus, 71 Glucocorticoid, 1087 GIuRI, 383 Glutamate, 699,727 Glutamate receptor, 383, 1057 Glutamate receptors, 351 Glutamate release, 363,395 Glutamate co-transporters, 395 Glutamate decarboxylase immunocytochemistry, 1159 Glycoproteins, 331 Golgi impregnation, 83, 89 Growth factor, 781 Guinea-pig, 495

Habituation, 371 Hamster, 1005 Harmonic analysis, 271 Heart rate, 459 Heat stroke, 395 Hermaphrodite snail, 1275 Hexamethonium axotomy, 651 I-Iippocampus, 1,139,821,339,699, 831,407, 1067, 1111 I-Iiptx~arnpal slices, 1057 Histogram, 271 Human brain, 339 Huntington's disease, 43, 1025 Hypothalamus, 167

Ibotenic acid lesion, 1169 Immediate early genes, 199 Immunocytochemistry, 383,441, 1031 Immunofluorescence, 797 Immunohistochemistry, 545,309, 71, 1005 Implant, 619 Impulse activity, 661 In situ hybridization, 167, 1103, 1025 In vivo dialysis, 1067 Inactivation, 331 Inflammation, 297 Inhibition, 371,739 Innervation, 797 Inositol, 125 Inositol 1,4,5-trisphosphate receptor, 1239 Inositol 1,4,5-trisphosphate receptor mRNA, 1239 Instructive effect, 771 Insular cortex, 533 Internal capsule, 177 Interneurons, 99 Intracellular recordings, 467 Intracellular recording and labelling, 601 Intrinsic connections, 567 Ion channel, 1031 Ion channels, 331

K + channel, 1119 Kainate, 477, 1159 Kainic acid, 705 Kappa-opioid, 345

Kindling, 567 KN-62, 585

L-2-amino-4-phosphonobutyric acid, 167 Large dense-core vesicle, 977 Laser lesions, 407 Laser-Doppler, 1195 Lateralization, 507 Laterodorsal tegmental nucleus, 1183 Learning, 821, 1087 Learning and memory, 1075 Limbic system, 831,371 Locomotion, 661 Long-term potentiation, 363,781

M6, 1169 Macaca fascicularis, 71 Macrophage, 177 Magnesium, 477 MAPK, 1103 Mating, 585, 1075 Maturation, 781 Medial vestibular nucleus, 661 Median raphe nucleaus, 189 Membrane potential, 915 Memory, 821, I Mesolimbic dopamine neurons, 417 Microdiaiysis, 1075 Midbrain tegmentum, 507 MK-801, 417 Mossy fibres, 705, 831 Motor neurons, 321 Mu-opioid, 345 Multiple stress, 83 Muscle spindles, 321

N-methyl- D- aspartate, 477 NADPH-diaphorase, 985 NANC, 643 NCAM, 1087 Neocortex, 727 Neonatal steroid environment, 519 Nervous system, 331 Neural grafting, 407 Neural tube, 309 Neurofibrillary degeneration, 691 Neurofibrillary tangles, 691 Neurohypophysial, 997 Neurokinin A, 643 Neuroleptics, 881 Neuromuscular junction, 271 Neuron, 1031 Neuronal guidance, 309 Neurons, 283 Neuropathology, 107 Neuropathy, 955 Neuropeptide Y, 847 Neuropeptide tyrosine (NPY), 1019 Neuropeptides, 711 Neurostereology, 151 Neurotoxicity, 351 Neurotrophic factors, 619 Neurotrophin, 1133 Neurotrophins, 321, 763 Neutric plaques, 691

xiv

Nicotine, 939 Nicotinic acetylcholine receptors, 221 Nictitating membrane, 459 Nimodipine, 955 Nisoxetine, 259 Nitric oxide, 643, 1013 Nitric oxide synthase, 545, 1195, 1253 Nitro-L-arginine, 1195 Nitrous oxide, 1013 NMDA single channel currents, 363 NMDA, 781 NMDAreceptors, 89, 241, 351 Nociception, 685, 931 Non-synaptic, 711 Nonsynaptic transmission, 99 Norepinephrine transporter, 259 NOS, 771 Nucleus accumbens, 417, 881

Oculomotor nuclei, 671 Okadaic acid, 691 Olfaction, 1075 Olfactory, 167 Olfactory tubercle, 159 Opioids, 241 Oral irritation, 939 Orbital afferents, 671 Organotypic cultures, 99 Orienting, 507

Pain, 931,955, 1013 Paired pulse facilitation, 727 Parabrachial nucleus, 533 Parzen estimate, 271 Passive avoidance, 1087 Patch-clamp, 139, 1057 Pedunculopontine tegmental nucleus, 1183 Pentazocine, 345 Perifornical area, 533 Peripheral nervous system, 955 Peristalsis, 1275 Pertussis toxin, 1145 Pharmacology, I Pheromone, 585 Photic entrainment, 545 Pipcrine, 939 Pituitary gland, 159 Plasticity, 781 Polyamines, 591 Polymerase chain reaction, 869 Polymicrogyria, 107 Postembedding immunostaining, 1205 Potassium current, 915 Prefrontal cortex, 821,859 Pregnancy block, 585 Presympathetic (sympathoexcitatory) neurons, 601 Presynaptic, 167,727 Primate, 859 Programmed cell death, 893 Proprioception, 321 Prostaglandin D synthase, 967 Protective factor, 757 Protein kinase C isozymes, 1239

Psychomotor stimulant, 233 Psychomotor behavioural sensitization, 233 Pyramidal neurons, 83

Quantitative binding, 43 Quinpirole, 1145

R-(+)-HA-966, 233 Rat, 371, 1005 Receptor-induction, 685 Recognition, 821 Reflex arc, 249 Regeneration, 619 Restraint, 83 Retinohypothalmic tract, 545 Retrograde labelling, 1253 Retrograde tracing, 1019, 1205 Rhinal cortex, 821 Ribosomes, 967 Risk factor, 757 Rough endoplasmic reticulum, 967

SAPK, 1103 Selective graft removal, 407 Sensorimotor functions, 507 Septal nuclei, 371 Serotonin, 99,903 Signal transduction, 869 Silencer, 807 SIN 1, 1195 Size distribution, 151 Sleep, 495 Sodium nitroprusside, 459

Soma, 115 Somatosensory neurons, 507 Somatostatin, 847 Spatial memory, 1067 Spermine, 477 Spike responses, 115 Spinal cord, 167, 931, 1263 Spinal cord injury, 619 Spines, 383 Sprouting, 763, 831 Stereology, 151 Stress, 209,233 Striatal neurons, 869 Striatal development, 1169 Striatum, 1, 71,859, 881,893 Substance P1-7, 1263 Substance P, 241, 643,847, 1263 Substantia nigra, 71 SuprachJasmatic nucleus, 915 Supraoptic nucleus, 997 Suramin, 651 Surgical trauma, 241 Sympathectomy, 685 Sympathetic ganglia, 1019 Sympathoadrenal system, 1253 Synapse, 727, 739, 985, 1031 Synaptic plasticity, 699, 1075 Synaptic protein, 339 Synaptic density, 339

Tachykinins, 831 Testosterone, 159 Tetraethylammonium,915 Tetrodotoxin, 859, 1133

Thalamus, 821, 1183 Toxins, 627 Tract development, 309 Transcription factors, 441, 807 Transforming growth 'factor alpha, 1025 Transmitter phenotype, 771 Trigeminal system, 671 Trigeminal nucleus caudalis, 939 trk receptor, 1133 Tropism, 619 T y r o s i n e h y d r o x y l a s e immunocytochemistry, 1159 Tyrosine hydroxylase, 601

Ultraviolet photoreceptors, 1005 Uptake binding sites, 259

Vasoactive intestinal polypeptide, 1019 Ventral tegmental area, 417 Vestibular stimulation, 661 Visual system, 1133 Visual cortex, 821 Voltage-activated calcium channels, 221

Whole-cell patch clamp, 903

Xenograft, 1169

Zinc, 477 [3H]ketanserin, 1119

XV