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2014 Beijing Conference
Transforming Canada-China Educational Cooperation:
Significant Legacies and Future Challenges
Tsinghua UniversityBeijing, ChinaMay 9-10, 2014
Cardiovascular textiles: spectacular achievements of the
Donghua University/Laval University collaboration
Lu WANGDonghua University, Shanghai, China
Robert GUIDOINLaval University, Québec, Canada
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History3
Late 2006, the Ministry of Education in Beijing approved the International collaborative project entitled :"Biomaterial Textile Materials Science and Technology, No. B07024", also known as "111 Project".
Since 2007, Donghua University at the Songjiang Campus, Shanghai has been hosting a yearly International Forum on Biomedical Textile Material co-chaired by Professor Lu Wang from Donghua University and Professor Martin King from NCSU, Raleigh, US.
Summary4
Summary5
Summary6
The 111 project Joint collaborative research projects between
foreign scholars, Chinese university professors, healthcare professionals and graduate students.
Visitation of foreign scholars with the purpose of giving lectures and providing direction and collaboration, the writing and submission of grant proposals, the undertaking of research activities and the publication of original research findings in refereed scholarly journals.
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Focus areas8
Based upon the evaluation of the biomedical textile materials technology, the ministry of Education recommended the integration of the following concepts:1.Chemical modification technology of fiber materials, that is grafting therapeutic medicine on fiber materials and generating persistent and centralized treatment effect on the diseased tissues.
Focus areas9
2. Manufacture and characterization of electro spinning nano-fibers, influence of size and surface effects of nano-fibers on the growing environment of tissue cells.
3. Develop biotextile devices and tissue engineering scaffolds by multiple advanced textile manufacturing technologies.
Focus areas10
4. Develop functional patches and special equipments and quality assurance system for vascular prostheses.
5. Establish laboratory testing and evaluation system for internal tubular prostheses.
Participants with 111 project11
The participants in the project include fifteen international “guest” professors and nine professors from Donghua University. The fifteen “guest” professors come from nine different countries outside China and cover a wide range of disciplines and research interests related to medical applications in textiles. The common thread that weaves their interests together is the subject of biomedical textile materials and the application of science and technology to the design and development of medical textile and biotextile products for improved healthcare.
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The Donghua University professors, who are participating in the project, have an equally diverse range of research and teaching interests, and are associated with the College of Textiles, Materials Science & Engineering and the Institute of Biological Sciences and Biotechnology (IBSB).
Participants with 111 project
Chairperson:Dr. Martin W. King North Carolina State University, USA
Members:
The first International Forum on Biomedical Textile Materials and Annual Meeting of the "111
Project " - May 30-June 2, 2007
Dr. James ANDERSON, MD Case Western Reserve University, Cleveland, USA
Dr. BAI Lun Soochow University, Soochow, PR China
Dr. CAO Yilin Shanghai JiaoTong, Shanghai, University, PR China
Dr. C.C. CHU Cornell University, Ithica, USA
Dr. George DU Gangwu InterVascular Inc., Clearwater, USA
Dr. GU Zhongwei Sichuan University, Chengdu, PR China
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Dr. Robert GUIDOIN Laval University, Québec, Canada
Dr. Lubos HES Technical University of Liberec, Liberec, Czech Republic
Dr. Dietmar W. HUTMACHER Queensland University of Technology, Brisbane, Australia
Dr. KIM Soo-Hyun Korean Institute of Science & Technology, Seoul, South Korea
Dr. Georgi MARINOV, MD Medical University of Varna, Varna, Bulgaria
Dr. Pertti NOUSIAINEN Tampere University of Technology, Tampere, Finland
Dr. PAN Ning University of California, Davis, USA
Members
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Dr. QING Fengling Donghua University, Shanghai, PR China
Dr. Seeran RAMAKRISHINA National University of Singapore, Singapore, Thailand
Dr. SUN Gang University of California, Davis, USA
Dr. Bojana VONCINA University of Maribor, Maribor, Slovenia
Dr. WANG, Lu Donghua University, Shanghai, PR China
Dr. XI Tingfei National Institute for the Control of Pharmaceutical & Biological Products, Beijing, PR China
Dr. XIAO Zhicheng, MD Singapore General Hospital, Singapore, Thailand
Members
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Organization of the 111 project18
1) Advancing research in biomedical textile materials: the discipline of textile service and engineering was promoted.2) Developing and maturing of talented scientists.3) Cultivating talented researchers and research teams.4) Stable cooperation relationship.5) Frequent and effective academic exchanges.
Collaboration Donghua University and Laval University
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1) Developing major research projects on the evaluation of devices (stent-graft, percutaneous valves) harvested at autopsy or reoperation, the validation of concepts for new commercially available devices, the development of innovative blood conduits to prevent fatigue and endoleaks.
2) Training of graduate students to link textile material and technology issue to biological requirements with the 3Bs concept of biocompatibility, biofunctionality and biodurability as its central paradigm.
3) Supporting independent programs to open new avenues regarding biofunctionalized materials, innovative textiles materials and customized technologies.
Summary20
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Support of teaching at Donghua University
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Undergraduate program: high technology textiles and functional materials, biomedical textile and technology.Graduate program leading to a master or PhD degree. The program was approved in 2009 and the first students were enrolled in 2010: 10-15 MSc, 6 PhD.Training, encouraging and supporting students to participate in Innovation competitions: 2 gold medals and 1 silver medal.
Young teachers involved in collaborative projects
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Name Degree Project Year
Fujun Wang PhDCuffs for
fenestrated stent-grafts
2007-to 2014
Jing Lin PhD
In vitro fatigue simulation for
stent- grafts and in situ fenestration of
stent grafts
2009-to now
Guoping Guan PhD
Silk/Polyester small diameter
vascular prostheses
2009-to now
Students involved in collaborative projects
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Name Degree Project Year
Xu, Lu MSc Degradation of polyester grafts 2006 - 2009
Jiang, Hua MSc Compliance testing 2007 - 2010
Ji, Xiaoping MSc PTFE structures and properties;weft knitting fabric for stent-grafts 2008 - 2011
Liu Bing MSc Stent-graft fatigue 2011 - 2013
Guan, Xiaoning MSc Biostability study of stent-grafts 2012 - 2014
Zou, Qiuhua MSc Valsalva 2013 - 2015
Miao, Linli MSc Meshes hernia 2013 - 2015
Zhao, Huijing PhD Fatigue of stent-grafts 2006 - 2009
Fu, Yijun PhD Valsalva and stent-grafts 2012 - 2015
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Achievements26
1) Conferences, communications, abstracts: (21 since 2007): UK, 2; Canada, 4; USA, 2; Finland, 1; Hong Kong, 1; China, 11.
2) Publications: (22 since 2007); published, 11; submitted, 6; in preparation, 5.
Understanding of cooperation27
Donghua University and Laval University signed an understanding of cooperation late 2012 thereby further cementing the long lasting and fruitful cooperation between our two institutions. A new era just began and we are confident in a bright future.
Laval University Team28
Robert Guidoin, PhD, Professor of Surgery (Biomaterials)Yvan Douville, MD, Head of the Department of SurgeryZe Zhang, PhD, Professor of Surgery (Biomaterials)Denis Desaulniers, MD, Professor of SurgeryGuy Dionne, MD, Professor of RadiologyGaétan Brochu, MD, Professor of Surgery
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Conclusion 130
This collaboration between Laval University and Donghua University has resulted in significant scientific advances in the field of biomedical textiles and more specifically the textiles employed to manufacture percutaneous devices for minimally invasive technology. The know-how that was acquired during the last 7 years should now be extended to other medical implants made of textiles. The development and analysis of new hernia patches are now part of the program.
Conclusion 231
The training of students is considered to be a top priority by both institutions. The students in medical textiles must be exposed more actively to the medical field for example by attending surgical operations as observers. This would provide them with a better understanding of the medical and surgical environment and an appreciation of the requirements of the medical community and patient concerns.
Conclusion 332
The minimally invasive technology has been mostly industry driven during the first two decades of its development and has rapidly reached a plateau. The academic research has demonstrated how it can influence and contribute to the development of new generations of devices to permit more patients to benefit of this technology. A better collaboration with industry and medical doctors will enable us to achieve new summits. In the meantime, a financial support from industry would be of considerable help for the academic research.
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