UCLA CTSI Clinical and Translational Science Institute

Steven Dubinett, MD Director, Clinical and Translational Science Institute Associate Vice Chancellor for Research

UC BRAID OVERVIEW June 20, 2014

brings UCLA innovations to the greatest health needs in Los Angeles

www.ctsi.ucla.edu

NIH CTSA Consortium

University of California, Los Angeles

CTSA Regional Consortia

4  

•  A committee of the CTSA PIs at UC Davis, San Diego, San Francisco, Irvine and Los Angeles

•  Initial focus on contracting, informatics and IRBs

•  Drug discovery and development (D4)

•  Biobanking and global consent

•  Child Health Research

•  Working toward inclusion of UCLA CTSI partner institutions

UC Biomedical Research Acceleration Integration and Development (UC-BRAID)

5  

UC Biomedical Research Acceleration Integration and Development (UC BRAID)

6  

Engage UC •  Global consent and biobanking •  $2-million in supplemental funding from NCATS

Partnership to Accelerate Clinical Trials (PACT) •  PACT is a Consortium of California clinical trial sites committed to supporting

efficient start-up and execution of clinical studies, speeding development of new therapies

Patient Centered Outcomes Research Institute (PCORI) Patient-Oriented Scalable National Network for Effectiveness Research (p-SCANNER)

•  Will integrate data from three networks covering 21 million patients •  Develop novel methods for distributed analyses

—  Can take place without moving patient data to central location

UC Center for Accelerated Innovation •  Advance translational potential of our discoveries in heart, lung and blood

diseases

Major Initiatives As of 2012, our five campuses account for nearly 7% of NHLBI’s grant funding.