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UCSF LIfe Sciences: Week 6 Therapeutics Partners

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Karl Handelsman Codon Capital Weekly Office Hours: 4:305:30 before class [email protected] Partners Lean Launchpad: TherapeuFcs UCSF Entrepreneurship Center November 5, 2013
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Value PropositionsLean Launchpad: Digital Health

UCSF Entrepreneurship CenterOctober 1, 2013

Abhas Gupta, MDMohr Davidow Ventures

@abhasguptamd

Karl  Handelsman  Codon  Capital    

Weekly  Office  Hours:  4:30-­‐5:30  before  class  

[email protected]  

Partners  Lean  Launchpad:  TherapeuFcs  

 UCSF  Entrepreneurship  Center  

November  5,  2013    

Value PropositionsLean Launchpad: Digital Health

UCSF Entrepreneurship CenterOctober 1, 2013

Abhas Gupta, MDMohr Davidow Ventures

@abhasguptamd

Partnerships  and  OperaFons  

This  Week  

Next  Week  

Who  are  the  key  partners  and  suppliers  needed  to  make  the  business  model  work?  

Next  Week  

Value PropositionsLean Launchpad: Digital Health

UCSF Entrepreneurship CenterOctober 1, 2013

Abhas Gupta, MDMohr Davidow Ventures

@abhasguptamd

PARTNERS  BiotechExamples  

Value PropositionsLean Launchpad: Digital Health

UCSF Entrepreneurship CenterOctober 1, 2013

Abhas Gupta, MDMohr Davidow Ventures

@abhasguptamd

Keep  things  in  perspecFve  Pharma  has  exisFng  products,  a  mulF  billion  dollar  research  budget,  a  pipeline  of  products  at  every  stage.    Your  Fny  company  has  an  idea  that  needs  proof  of  relevance.  

“Big  things  have  small  beginnings”  

Value PropositionsLean Launchpad: Digital Health

UCSF Entrepreneurship CenterOctober 1, 2013

Abhas Gupta, MDMohr Davidow Ventures

@abhasguptamd

Types  of  Partnerships  

Strategic  Alliances  

Joint  New  Business  

Development  Efforts  

CoopeFFon  

Key  Supplier  RelaFonships  

Joint  Ventures  

Value PropositionsLean Launchpad: Digital Health

UCSF Entrepreneurship CenterOctober 1, 2013

Abhas Gupta, MDMohr Davidow Ventures

@abhasguptamd

Why  have  partners?  

•  More  efficient  use  of  capital  •  Leverage  exisFng  capabiliFes  and  technologies  – Build  vs  Buy  vs  Rent    much  more  than  cost    

•  Time,  Focus,  Quality,  Talent,  ReputaFon,  SpecializaFon  

•  Unique  customer  knowledge  or  experFse  – Plexxicon/Roche  (formulaFon/manufacturing)  

Value PropositionsLean Launchpad: Digital Health

UCSF Entrepreneurship CenterOctober 1, 2013

Abhas Gupta, MDMohr Davidow Ventures

@abhasguptamd

Roche  decides  to  re-­‐enter  anFbioFcs  

$40  million  upfront  and  up  to  $520  million  for  a  range  of  milestones  covering  development  and  commercializaFon  work.  

Value PropositionsLean Launchpad: Digital Health

UCSF Entrepreneurship CenterOctober 1, 2013

Abhas Gupta, MDMohr Davidow Ventures

@abhasguptamd

CooperaFon    

What  are  the  pharma  moFvaFons  to  cooperate?      Why  is  this  good  for  Ablexis?  

What  about  control?  Did  Ablexis  cap  their  upside?  

     

           

+  5  Undisclosed  

Value PropositionsLean Launchpad: Digital Health

UCSF Entrepreneurship CenterOctober 1, 2013

Abhas Gupta, MDMohr Davidow Ventures

@abhasguptamd

 H3  Biomedicine:  coordinaFon  of  

mulFple  partnerships  $200M  

Novel  cancer  target  discovery/validaFon  

Upfront  and  m

ilestones    

Pre-­‐Clinicial:IND  Cand

idate  Conduct  Clinical  Trials  

Cancer    BioinformaFcs  Cancer  Genome  Atlas  

$6.7M  grant  

Value PropositionsLean Launchpad: Digital Health

UCSF Entrepreneurship CenterOctober 1, 2013

Abhas Gupta, MDMohr Davidow Ventures

@abhasguptamd

[email protected]  My  Contact:  Put  LLP  in  Subject  Line  for  extra  points    


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