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Umang presentation pharma 2014

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2014 Version 5
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Page 1: Umang presentation pharma 2014

2014Version 5

Page 2: Umang presentation pharma 2014

Umang Pharmatech Pvt. Ltd.Umang was incepted in the year 1982, with an objective to serve the clients with all kinds of

equipments and accessories under one roof. Within a very short passage of time, we succeeded to be

the most reliable brand name in the market.

Umang offer pharmaceutical machineries having matched quality of international standards. Our

team is comprised of highly dedicated and hard-working employees, who work day and night and give

their best to company. They are backed by the latest techniques and most advance equipments that

enhances the grades of productivity. Our R&D department checks each and every product minutely so

Mission / Vision:Quality is the governing factor in all of our endeavours. At UPPL our goal is to know the exact need of

our customers and provide products and services to their complete satisfaction. The foundation of

this goal is to build a total commitment towards quality. On time delivery of error free,

technologically advanced products with superior Service / Support is what our customers expect and

receive from UPPL. Complete customer satisfaction is an open-ended process, which we continually

strive to improve. We believe that these improvements will result only by reviewing performance

measurements in a timely manner and by utilizing a live and functioning quality improvement

process.

that only best product is served to you. With rich experiences in manufacturing pharmaceutical machineries, the company has

established long-term business relations with domestic and international customers.

Page 3: Umang presentation pharma 2014

HME Pellets/ Granules

MatrixPellets

NeutralPellets

MouthDissolving

Film

NutraceuticalPellets

Films inCapsules /

Tablets

EntericCoatedPellets

CombinationPellets

LayeredPellets

SustainedReleasePellets

MicroPellets

NutraceuticalPellets

Page 4: Umang presentation pharma 2014

Sustained Release PelletsReady to fill sustained release pellets made from our equipments.

Page 5: Umang presentation pharma 2014

PharmaceuticalsAceclofenacAlfuzosine HydroclorideAllopurinalAmbroxol Hydrocloride CaffeineCarvedilol PhosphateChlorphenaramine MaleateChondroitin SulphateCinitaprideDiclofenac PotassiumDiclofenac SodiumDiltizam HydroclorideDipyridamoleDomperidoneDried ferrous sulphateDuloxetine HClErythromycin StearateFerrous FumarateFerrous GluconateFluoxetine HCl GlicazideGlimepirideGlipizideGlucosomine sulphateIbuprofenIndomethacinIsodexuprine hydrochlorideIsosorbide DinitrateIsosorbide HydrocholorideIsosorbide mononitrate

Dosage27 / 30 mg5 mg70 mg27 / 30 mg50 mg10 / 20 / 40 / 80 mg8 mg30 / 70 mg1.45 mg50 mg50 mg80 mg200 mg20 / 30 / 40 mg65 mg40 mg25 mg50 mg50 mg20 mg25 mg1 mg10 mg65 mg50 / 70 mg25 / 27.5 / 50 / 60 mg16.80%20% / 40%20%20%

TherapeuticalNSAIDBenign Prostate Hyper PlasiaTreatment of Hyper uricemiaAnaesthetic, Acute sore throatStimulantAnti HypertensiveAntihistamine, AntiallergicAnti inflammatoryAnti ulcer agentNSAIDNSAIDHypertensionPlatelet aggregation InhibitorAntiemeticAnti- anaemicAnticonvulsant and antidepressantAnti- infectiveHaematinicHaematinicSelective Serotonin reuptake InhibitorAntidiabeticAntidiabeticAntidiabeticDietary supplement for adultNSAIDNSAIDCerebral vascular deficiencyAnti anginalHypertension, Angina pectorisHypertension, Angina pectoris

Sustained Release Pellets - Formulation

Page 6: Umang presentation pharma 2014

PharmaceuticalsIsoxsuprine HCl Itopride hydrochlorideKetoprofenLactobacillus SporogenesMebeverine HClMesalamine MetforminNifedipineNimesulideNitroglycerinOxybutyninParoxetine HCl Phenyl propanolamine HClPhenylephrine HClPropanalol HClSalbutamol SulphateTamsulosin HClTerbutaline SulphateTheophylineTolterodine TartrateTramadol HClTrimetazidineVenlafaxine HClVeramapilVincamineVitamin CZinc sulphate monohydrate

Dosage16.8 / 22 / 40 mg60 mg33 / 65 mg50 mg50 mg90 mg75 mg10 / 20 mg30 mg2.5 / 2.6 / 6.4 mg5 / 10 / 15 mg21 mg5 mg20 mg11 / 40 mg5 mg0.2 / 0.11 mg7.5 / 20 mg60 mg2.1 mg60 mg50 mg33 / 40 / 50 mg40 mg30 mg90 mg65 mg

Therapeutical Cerebral vascular deficiencyDyspepsia, Gastric disordersNSAIDDietary supplementG.I.Spasm, Bowl movementG.I.Spasm anti inflammatoryAntidiabeticPulmonary hypertensionNSAIDAntianginalAnti spasmodicAnti DepressantSympathometic DecongestantNasal DecongestantNon selective Beta BlockerAntiasthamaticAlpha adrenergic blockerBronchodialatorAnti asthamaticTreatment of Overactive bladderSynthetic opioid analgesicAntianginalAnti DepressantAntiarrhythmicCerebral vasodialatorVitamin SupplementZinc Supplement

Sustained Release Pellets - Formulation

Page 7: Umang presentation pharma 2014

Enteric Coated PelletsReady to fill enteric coated pellets made from our equipments.

Page 8: Umang presentation pharma 2014

Pharmaceutical PelletsDoxycycline HyclateDuloxetine HClFluoxetineAspirin EC micropellets (pellets for tabletting)AspirinBudesonideEsomeprazole MagnesiumLactic Acid BacillusLansoprazoleOrnidazolePancreatinOmeprazoleDexarabeprazole Dexalansoprazole

Dosage in Capsules25, 35.17, 60 mg13.2, 20 mg50 mg65 mg50, 60, 75 mg1.25 mg8.5, 22.5 mg60.6 mg8.5 mg60 mg90 mg8.5, 20, 30 mg8 mg20 mg

TherapeuticalAnalgesic, AntipyreticAnti DepressantAntidepressantAcid Reflux, Heart BurnAnalgesic, AntipyreticGlucocorticoid Steroid for AsthmaProton pump inhibitorsStomatitis, HypochlorhydriaProton pump inhibitorsAnti infective, Antibacterial agentDiegstive enzymeProton pump inhibitorsProton pump inhibitorsProton pump inhibitors

Enteric Coated Pellets - Formulation

Page 9: Umang presentation pharma 2014

Combination PelletsReady to fill enteric coated pellets made from our equipments.

Page 10: Umang presentation pharma 2014

Pharmaceutical PelletsOmeprazole EC + Domperidone IROmeprazole EC + Domperidone IROmeprazole EC + Domperidone SRLansoprazole EC + Domperidone IRLansoprazole EC + Domperidone SRRabeprazole EC + Domperidone IRRabeprazole EC + Domperidone SRRabeprazole EC + Domperidone SRRabeprazole EC + Diclofenac Sodium SRRabeprazole EC + Diclofenac Sodium SRDexrabeprazole EC + Domperidone SREsomeprazole EC+ Domperidone SREsomeprazole EC +Domperidone SRPantoprazole EC + Domperidone IRPantoprazole EC + Domperidone IRPantoprazole EC + Domperidone SRPantoprazole EC + Domperidone SRPantoprazole EC + Itopride HCl SR Rabeprazole EC+ Itopride SRCPM + Phenylephrine HCl + Detromethorphan + ParacetamolAspirin EC + AtorvastatinAspirin EC + ClopidogrelAspirin EC + Atorvastatin + ClopidogrelEzitimibe + FenofibrateParacetamol + CPM + PPHCl + Dextromethorphan HBRDried Ferrous Sulphate + Folic Acid + Zinc Sulphate MonohydrateChlorphenaramine Maleate + Phenylephrinc HClOxytetracycline HCl + Phenazophyridine + SulphathaizoleItopride SR + Pantaprazole Sodium ECParacetamol + Caffeine + Diclofenac SodiumParacetamol + CPM + PPHCl + Caffeine

Dosage10 +10 mg20 + 10 mg20 + 30 mg30 + 10 mg30 + 30 mg20 + 10 mg20 + 30 mg20 + 20 mg10 + 50 mg20 + 100 mg20 + 100 mg20 + 30 mg40 + 30 mg20 + 10 mg40 + 10 mg40 + 20 mg40 + 30 mg40 + 150 mg20 + 150 mg2+10+15+500 mg75 + 10 / 150+ 20 mg75 + 75 / 150+75 mg75+10+75 / 150+20+75 mg10+150500 mg + 2 mg + 10 mg + 15 mg150 mg + 0.5 mg + 61.8 mg2 mg + 10 mg250 mg + 50 mg + 125 mg150 mg + 40 mg500 mg + 30 mg + 50 mg500 mg + 4 mg + 5 mg + 30 mg

Combination Pellets - Formulation

Page 11: Umang presentation pharma 2014

Layered PelletsReady to fill enteric coated pellets made from our equipments.

Page 12: Umang presentation pharma 2014

PharmaceuticalsItraconazoleCetirizineDomeperidoneAtorvastatinPiroxicamLoratidineFolic AcidSalbutamolBromohexine Hcl

Dosage22 mg4, 8 mg20 mg10 mg9 mg5 mg3 mg10 mg8 mg

TherapeuticalAntifungal agentAntihistamine, AntiallergicAntiemetic Lowers cholesterol level in bloodNSAIDAntihistamineTreatment of folic acid deficiencyBronchodialatorMucolytic agent

Layered Pellets - Formulation

Page 13: Umang presentation pharma 2014

Micro PelletsReady to fill enteric coated pellets made from our equipments.

Page 14: Umang presentation pharma 2014

PharmaceuticalsCetirizineChlorphenaramine MaleateEsomprazole ECIbuprofenLansoprazole ECOmeprazole ECPiroxicam

Dosage10 mg8 mg22.5 mg50 mg, 60mg, 90 mg8.5mg,20 mg8.5mg,20 mg,30mg10 mg

TherapeuticalAntihistamineAntiallergicProton pump inhibitorNSAIDProton pump inhibitorProton pump inhibitorNon steroidal anti inflammatory

Micro Pellets - Formulation

Page 15: Umang presentation pharma 2014

Matrix PelletsReady to fill enteric coated pellets made from our equipments.

Page 16: Umang presentation pharma 2014

PharmaceuticalsAlpha Lipoic AcidArepitantAscorbic AcidAspirinCaffeineCarbonyl IronClopidogrelCyanocobalaminDesloratadineDiclofenac SodiumDidanosineDomperidoneFluconazoleMethylcobalaminOrlistatPyridoxine HClSimethiconeThiamine MononitrateTolperisone HClTramadolVitamin D3Zinc Sulphate

Dosage70 mg40 mg62.5 mg50 mg50 mg50 mg50 mg0.04 mg50 mg50 mg60 mg20 mg60 mg1.5 mg50 mg5 mg50 mg10 mg65.8 mg60 mg50 mg50 mg

TherapeuticalAntioxidantAdjunctive AntiemeticVitamin C deficiency, Anti oxidantAnalgesic, AntipyreticStimulantIron Deficiency, Food SupplementVascular ischemia, Antiplatelet agentAnti anaemic agentTreatment of AllergiesNSAIDAntiretroviralAnti emetic AgentAntifungalTreatment of anaemia, Vit B12 deficiencyAnti obesityVitamin SupplementAntiflatulentTreatment of Vit B deficienciesMuscle relaxantSynthetic opioid analgesicDietary supplementAnti-infective agent

Matrix Pellets - Formulation

Page 17: Umang presentation pharma 2014

HME PelletsReady to fill enteric coated pellets made from our equipments.

Page 18: Umang presentation pharma 2014

PharmaceuticalsClarithromycin taste maskDiclofenac Potassium SRDiclofenac Sodium CRDomperidoneIbuprofen SRNifedipineParacetamol SR

Dosage80 mg50 mg50 mg40 mg90 mg20 mg70 mg

TherapeuticalMacrolide, AntibioticNSAIDNSAIDAntiemeticNSAIDPulmonary hypertensionNSAID

HME Pellets - Formulation

Page 19: Umang presentation pharma 2014

Mouth Dissolving Film

Page 20: Umang presentation pharma 2014

PharmaceuticalsAmbroxolAtorvastatinBenzocaineBetamethasoneBromhexine HClCaffeineCetirizineDextromethorphan HBrDicylcomineDiphenhydramine hydrochlorideDoxazosineFamotidineFluorideFluoxetineFolic acidFolic acid+ Vit B6+ Vit CGlimepirideGranisetronHaloperidolKetoprofenLevocetirizine LoperamideLoratidineLornoxicamMedizine hydrochloride

Dosage30 mg10, 20 mg6 mg8 mg4, 8, 16 mg25, 50 mg5 mg, 10 mg7.5 mg/15 mg10 mg12.5 mg, 25 mg10 mg10 mg & 20 mg20 mg2.5 mg & 5 mg5 mg0.5+1.0+25 mg1/2/3/4 mg1 mg0.5,1,2,5 mg5 mg5 mg10 mg5 mg4, 8, 12,16,24 mg7.5 mg

TherapeuticalMucolytic agentAnti hyperlipidemicSore throat & sore mouthCorticosteroid HormoneFor treatment of coughStimulantAntihistamine, Anti AllergiesCough and Cold PreparationAnalgesic, AntipyreticAntihistamine, AntiemeticNasal DecongestantCough and ColdAnalgesic, AntipyreticCough and ColdFolic Acid SupplementVitamin supplementsDiabetesTreatment of post operative nausea & vomitingPsychiatric illnessAntihistamine, Anti AllergiesRespiratory AgentAntihistamine, Anti AllergiesRespiratory AgentTreatment of Post operative painCough and Cold Preparation

Mouth Dissolving Film - Formulation

Page 21: Umang presentation pharma 2014

PharmaceuticalsMelatenin with methanolMentholMethylcobalaminMontelukastOlanzapineParoxetinePergolide mesylatePhenylephrine HClPhenylephrine HCl & Dextromethorphan HBrPhenylephrine HCl & Dextromethorphan HBrPhenylephrine HCl & Diphenhydramine HClPhenylephrine HCl & Diphenhydramine HClPiroxicamPseudoephedrineRisperidoneSalbutamol sulfateSildenafil citrateSimethiconeTadalafilTizanidineVitamin B12Vitamin C supplementVogliboseZinc histidinateZolpidem

Dosage5 mg2.5 mg1500, 3000, 6000 mcg4,5,10 mg2.5/5/7.5/10/15 & 20 mg2.5 mg15 mg2.5 mg/10 mg2.5 mg & 5 mg10 mg & 20 mg5 mg & 12.5 mg10 mg & 25 mg10 mg, 20 mg12.5 mg1/2/3/4 mg8 mg25, 50 mg50 mg10 mg, 20 mg25 mg1000 mcg20 mg0.2/0.3 mg10 mg5 mg & 12.5 mg

TherapeuticalNutritional supplementSore throatVitamin B12 SupplementPerennial allergic rhinitisAnti psychoticNasal DecongestantCough and Cold PreparationNasal DecongestantCough and ColdCough and ColdCough and ColdCough and ColdAnalgesic, AntipyreticAntihistamine, AntiemeticTreatment of SchizophreniaAntiasthamaticAnti-erectile dysfunction AgentAntiflatulent, Antifoam Agent Anti-erectile dysfunction AgentAntihistamine, AntiemeticVitamin SupplementAnti-erectile dysfunction AgentDiabetesTreatment of Zinc DeficiencyCough and Cold

Mouth Dissolving Film - Formulation

Page 22: Umang presentation pharma 2014

Product ListVitamin CCholecalciferolCalcium gluconate

Composition35 Mg200 Iu500 Mg

Mouth Dissolving Film – Formulation

Product ListVit B6Vit B12Blend of caffeineGinsengGinkgo bilobaCaffeine

Composition3 Mg7.5 Mg3.2 Mg26.4 Mg2.4 Mg15 Mg

Product ListMethylcobalaminCaffeine

Composition1000 μg per strip10 Mg

Product ListMucuna pruriens extractGinseng extractZinc sulphate monohydrate

Composition5 Mg2.5 Mg2.5 Mg

Product ListBenzocainLicorice extractJasmin leaf extract

Composition3 Mg15 Mg10 Mg

Product ListMint filmsAnethum sowa oil extractElettaria cardamomum oil extract

Composition15 Mg20 Mg10 Mg

Product ListZingiber officinale extractFagonia arabica

Composition25 Mg10 Mg

Product ListShankhapushpiAcocus calamusSatavari extract

Composition30 Mg10 Mg20 Mg

Product ListProprietary blend of papaya fruit,Peppermint leavesPlumbago zeylanicaCinnamon xylinum

Composition30 Mg

15 Mg10 Mg

Product ListCholecolciferol

Composition1500 μg

Product ListVitamin C

Composition50 Mg

Product ListRhus succedanea extractSolanum xanthocarpum extractSwertia chirata extract

Composition10 Mg5 Mg5 Mg

Product ListMelatoninTheanineJatamansi extract

Composition3 Mg15 Mg20 Mg

Page 23: Umang presentation pharma 2014

Films in Capsules / TabletsPharmaceuticalsPiroxicam

Percentage (%)10%

Dosage15 mg

TherapeuticalNon steroidal anti inflammatory

Bulk Phy. Form.Film

Final Dosage Form.Capsule / Tablet

Page 24: Umang presentation pharma 2014

Nutraceutical Pellets

Product Name

• Aloe Vera Beadlets• Artichoke Beadlets • Astaxanthin Beadlets • Ashwagandha Beadlets• Beta Carotene Beadlets • Boswellia Serrata Beadlets• Caffeine Beadlets • Cranberry Extract Beadlets • Coconut Oil Beadlets• Coenzymeeto Beadlets • Curcumin Beadlets• DHA Beadlets• Echinacea Beadlets • Epimedium Beadlets • Evening Primrose Oil Beadlets• Ginkgo Biloba Beadlets

Product Name

• Ginseng Root Beadlets • Glucosamine Sulphate Beadlets• Gotu Kola Beadlets • Grape Seed Beadlets • Green Tea Extract Beadlets• Liquorice Root Beadlets • Lutein Beadlets • Lycopene Beadlets• Milk Thistle Beadlets• Olive Beadlets• Pygeum Bark Soft Extract Beadlets• Resveratrol Beadlets • Rutin Beadlets• Saw Palmetto Beadlets • Soy Isoflavones Beadlets

Page 25: Umang presentation pharma 2014

Tartaric AcidPellets

MannitolPellets

SilicaPellets

MCCPellets

Acrylic CoatingPolymer

StarchPellets

LactosePellets

CalciumCarbonate

PelletsAcrylic Coating

PolymerSugarPellets

Page 26: Umang presentation pharma 2014

Sugar PelletsSugar Pellets Definitions:1. SPRAYSPHERES™ - SS contains not more than 92 percent of sucrose. Calculated on the dried basis. The dried basis. The remainder

consists of corn starch as per the European Pharmacopoeia.2. Compliance with Ph. Eur., USP/ NF and JP.3. Produced in accordance with the cGMP.

Sugar pellets particle size specifications:Particle size distribution (analyzed by laser diffraction) shows the symmetrical character of the distribution. The single model profile,associated a very homogeneous population of SPRAYSPHERES™ - SS.

Sugar Pellets Application:Used as cores to be coated in the manufacture of dry pharmaceutical / Nutraceutical / herbal / homeopathy form especially forcontrolled release & specially formulations.

SPRAYSPHERES™ - Speciality Products (SS):Definition:SPRAYSPHERES™ - SS base of sugar & starch pellets coated with cationic polymers.

Page 27: Umang presentation pharma 2014

1. Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.2. Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs / unstable drug.3. Using SPRAYSPHERES™ - SS can be converted to ready to fill pellet technology.4. Starter cores for Delayed release / Sustained release / time release / pulse release / Controlled release & Immediate release

applications, etc.

Application:

Mesh Size (ASTM)SS 120 - 140 #SS 100 - 120 #SS 80 - 100 #SS 70 - 80 #SS 60 - 70 #SS 50 - 60 #SS 45 - 50 #SS 45 - 60 #SS 40 - 60 #SS 18 - 20 #SS 16 - 20 #SS 16 - 18 #SS 14 - 16 #

Diameter In mm0.106 - 0.1250.125 - 0.1500.150 - 0.1800.180 - 0.2120.212 - 0.2500.250 - 0.3000.300 - 0.3550.250 - 0.3550.250 - 0.4250.850 - 1.0000.850 - 1.1801.000 - 1.1801.180 - 1.400

Mesh Size (ASTM)SS 40 - 50 #SS 40 - 45 #SS 35 - 55 #SS 35 - 50 #SS 35 - 45 #SS 35 - 40 #SS 30 - 35 #SS 25 - 30 #SS 20 - 25 #SS 12 - 16 #SS 12 - 14 #SS 10 - 12 #

Diameter In mm0.300 - 0.4250.355 - 0.4250.355 - 0.5000.300 - 0.5000.400 - 0.4500.425 - 0.5000.500 - 0.6000.600 - 0.7100.710 - 0.8501.400 - 1.7001.400 - 1.7001.700 - 2.000

Page 28: Umang presentation pharma 2014

Starch PelletsStarch Pellets Definitions:1. Starch spheres contain more than 92 percent of starch. Calculated on the dried basis. The dried basis. The remainder consists of sugar.2. Produced in accordance with the cGMP.

Application:1. Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.2. Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs / unstable drug.3. Using SPRAYSPHERES™ - STS can be converted to ready to fill pellet technology.4. Starter cores for Delayed release / Sustained release / time release / pulse release / Controlled release & Immediate release

applications, etc.

Mesh Size (ASTM)STS 12 - 14 #STS 16 - 18 #STS 18 - 20 #STS 20 - 30 #STS 80 - 100 #

Diameter In mm1.400 - 1.7001.000 - 1.1800.850 - 1.0000.600 - 0.8500.150 - 0.180

Mesh Size (ASTM)STS 30 - 40 #STS 40 - 50 #STS 50 - 60 #STS 60 - 80 #STS 100 - 200 #

Diameter In mm0.425 - 0.6000.300 - 0.4250.250 - 0.3000.180 - 0.2500.075 - 0.150

Page 29: Umang presentation pharma 2014

Lactose PelletsLactose Pellets Definitions:1. Lactose spheres contain more than 80 percent of lactose. Calculated on the dried basis. The dried basis. The remainder consists of

Starch.2. Produced in accordance with the cGMP.3. Completely for water soluble application a substitute for sugar.

Application:1. Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.2. Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs / unstable drug.3. Using SPRAYSPHERES™ - LS can be converted to ready to fill pellet technology.4. Starter cores for Delayed release / Sustained release / time release / pulse release / Controlled release & Immediate release

applications, etc.

Mesh Size (ASTM)LS 18 - 20 #LS 20 - 30 #LS 30 - 40 #LS 80 - 100 #

Diameter In mm0.850 - 1.0000.600 - 0.8500.425 - 0.6000.150 - 0.180

Mesh Size (ASTM)LS 40 - 50 #LS 50 - 60 #LS 60 - 80 #LS 100 - 200 #

Diameter In mm0.300 - 0.4250.250 - 0.3000.180 - 0.2500.075 - 0.150

Page 30: Umang presentation pharma 2014

Calcium Carbonate PelletsSPRAYSPHERES™ - CS1. Calcium Carbonate Neutral Pellets consist of CaCO3 and also used for the controlled release and MUPS formulations in Nutraceutical

and pharmaceutical medicine.2. Adapted for controlled release or sustained release formulations to produce spherical granules or pellets which have the most

suitable size and dissolution profile.

Calcium Carbonate Pellets Definitions:1. The SPRAYSPHERES™ - CS have been developed using calcium carbonate (90%) as base and other ingredient is maize starch.2. Calcium carbonate complying with Ph. Eur / USP / NF.3. Manufacturing in accordance with the cGMP.

Calcium Carbonate General Properties:1. Nearly white hard, uniform and spherical particles. (sphericity degree average >90%)2. Very low friability level.3. Calcium carbonate high physiochemical inertness improves the stability of the finished product.4. Uniform and consistent loading.5. Calcium give a improved taste and mouth feel for the pellets.6. For PH dependent applications

Calcium Carbonate Particle Size Specifications:1. Minimum of 92% (w/w) of SPRAYSPHERES™ - CS are between the lower and the upper limits of the size stated on the label.2. The SPRAYSPHERS™ - CS selection is obtained by the decreasing size by sieving method.

Page 31: Umang presentation pharma 2014

1. Used as cores to be coated in the manufacture of dry pharmaceutical forms. It enables greater accuracy and consistency in druglayering and coating.

2. Suitable for non-carcinogenic products.3. Ph controlled applications, these starter cores give a specific ph to the dissolution profile.4. Adopted to controlled release or sustained release formulations SPRAYSPHERES™ - CS make it easy to produce spherical micro

granules which have the most suitable size and dissolution profile to each specific purpose.

Calcium Carbonate Application:

Formulation

GradeCS -100CS-102CS-203CS-305CS-507CS-708

Particle size range (μm)75 - 212106 – 212150 - 300300 – 500500 - 710710 - 850

Page 32: Umang presentation pharma 2014

Tartaric Acid PelletsSPRAYSPHERES™ - TS1. Tartaric acid pellets and also used for the controlled release and MUPS formulations in nutraceutical and pharmaceutical medicine.2. Adapted for controlled release or sustained release formulations to produce spherical granules or pellets which have the most

suitable size and dissolution profile.3. Tartaric acid complying with Ph. Eur / USP / NF.4. Manufacturing in accordance with the cGMP.

Tartaric acid General Properties:1. Very low friability level.2. Tartaric acid high physiochemical inertness improves the stability of the finished product.3. Uniform and consistent loading.4. For PH dependent applications

Tartaric acid pellet Application:1. Used as cores to be coated in the manufacture of dry pharmaceutical forms. It enables greater accuracy and consistency in drug

layering and coating.2. Suitable for non-carcinogenic products.3. Ph controlled applications; these starter cores give a specific ph to the dissolution profile.

Particle size rangeTS 20 - 30 #TS 30 - 40 #TS 40 - 50 #TS 100 - 200 #

Diameter In mm0.600 - 0.8500.425 - 0.6000.300 - 0.4250.075 - 0.150

Particle size rangeTS 50 - 60 #TS 60 - 80 #TS 80 - 100 #

Diameter In mm0.250 - 0.3000.180 - 0.2500.150 - 0.180

Page 33: Umang presentation pharma 2014

Mannitol PelletsSPRAYSPHERES™ - MASMannitol Pellets Definitions:1. Mannitol spheres contain more than 80 percent of Mannitol. Calculated on the dried basis. The dried basis. The remainder consists of

Starch.2. Produced in accordance with the cGMP.3. Completely for water soluble application a substitute for sugar.

Application:1. Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.2. Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs / unstable drug.3. Using SPRAYSPHERES™ - MAS can be converted to ready to fill pellet technology.4. Starter cores for Delayed release / Sustained release / time release / pulse release / Controlled release & Immediate release

applications, etc.

Mesh Size (ASTM)MAS 18 - 20 #MAS 20 - 30 #MAS 30 - 40 #MAS 80 - 100 #

Diameter In mm0.850 - 1.0000.600 - 0.8500.425 - 0.6000.150 - 0.180

Mesh Size (ASTM)MAS 40 - 50 #MAS 50 - 60 #MAS 60 - 80 #MAS 100 - 200 #

Diameter In mm0.300 - 0.4250.250 - 0.3000.180 - 0.2500.075 - 0.150

Page 34: Umang presentation pharma 2014

Silica PelletsSPRAYSPHERES™ - ASSilica Pellets Neutral pellets Consist of SiO2 and mainly used as a core for drug loading of insoluble and instable drug. Also used in MUPStechnology.

Silica Pellets Definitions:1. The SPRAYSPHERES™ - AS have been developed using Silicon dioxide (< 75%) as base.2. Silica complying with Ph. Eur / USP / NF.3. Manufacturing in accordance with the cGMP.

Silica Pellets General properties:1. Nearly white hard, uniform and spherical particles. (Sphericity degree average >90%)2. Very low friability level.

GradeAS-100AS-102AS-203AS-305AS-507AS-708

Particle size range (μm)75 - 212106 – 212150 - 300300 – 500500 - 710710 - 850

Page 35: Umang presentation pharma 2014

MCC PelletsSPRAYSPHERES™ - MSMicrocrystalline Cellulose Pellets Neutral pellets for sugar free products, highly soluble & controlled released formulation products.

MCC Pellets Definitions:1. The SPRAYSPHERES™ - MS have been developed using microcrystalline cellulose (MCC) as base.2. Microcrystalline cellulose is purifies, partly depolymerised cellulose, prepared from alpha cellulose.3. MCC complying with Ph. Eur.4. Manufacturing in accordance with the cGMP.

MCC Pellets General properties:1. Nearly white hard, uniform and spherical particles. (Sphericity degree average >90%)2. Very low friability level.3. MCC high physiochemical inertness improves the stability of the finished product.4. Insoluble in water, absolute ethanol, acetone.

GradeMS-100MS-102MS-203MS-305MS-507MS-708

Particle size range (μm)75 - 212106 – 212150 - 300300 – 500500 - 710710 - 850

Page 36: Umang presentation pharma 2014

Lactose + MCC PelletsSPRAYSPHERES™ - MSMicrocrystalline Cellulose Pellets Neutral pellets for sugar free products, highly soluble & controlled released formulation products.

Lactose + MCC Pellets Definitions:1. The SPRAYSPHERES™ - MS have been developed using microcrystalline cellulose (MCC) as base.2. Microcrystalline cellulose is purifies, partly depolymerised cellulose, prepared from alpha cellulose.3. MCC complying with Ph. Eur.4. Manufacturing in accordance with the cGMP.

Lactose + MCC Pellets General properties:1. Nearly white hard, uniform and spherical particles. (Sphericity degree average >90%)2. Very low friability level.3. MCC high physiochemical inertness improves the stability of the finished product.4. Insoluble in water, absolute ethanol, acetone.

Diameter In mm0.300 - 0.4250.250 - 0.3000.180 - 0.2500.075 - 0.150

Mesh Size (ASTM)LM 40 - 50 #LM 50 - 60 #LM 60 - 80 #LM 100 - 200 #

Mesh Size (ASTM)LM 18 - 20 #LM 20 - 30 #LM 30 - 40 #LM 80 - 100 #

Diameter In mm0.850 - 1.0000.600 - 0.8500.425 - 0.6000.150 - 0.180

Page 37: Umang presentation pharma 2014

Acrylic Coating Polymer

Page 38: Umang presentation pharma 2014

Acrylic Coating PolymerL - 30 D - 55Application: Drug delivery in Jejunum.Functionality: Anionic polymer of methacrylic acid and ethacrylates with -COOH functional groups.

E - 100Application: Taste and odour masking, insolating coating, transdermal applications, moisture protection.Functionality: Cationic polymer with dimethylaminoethyl ammonium functional groups.

EPOApplication: Taste and odour masking, Insolating coating, transdermal applications, moisture protection.Functionality: Cationic polymer with dimethylaminoethyl ammonium functional groups.

Application: Drug delivery in Jejunum.Functionality: Anionic polymer of methacrylic acid and ethacrylates with -COOH functional groups.

L – 100

Application: Drug delivery in Jejunum.Functionality: Anionic polymer of methacrylic acid and ethacrylates with -COOH functional groups.

S – 100

Page 39: Umang presentation pharma 2014

www.umangpharmatech.com

www.umangpharmaceuticals.com

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www.pharmaceuticalpellets.com

www.pharmapelletization.com

Page 40: Umang presentation pharma 2014

Umang Pharmatech Pvt. Ltd.Survey No. 146, H. No. 1 (PT),Vasai Phata Highway Junction, Pelhar,

NH8, Vasai (E) - 401 208, Maharashtra (India).

Tel.: (+91-22) 30018900 / 30018915 - 98

Mob.: (+91) 98672 36594

Fax: (+91-22) 30018908 / 30018913

Skype: umang.budhraja

E-mail: [email protected]

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