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Week 11 Digestive System s2 2010

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DIGESTIVE SYSTEM Week 11
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DIGESTIVE SYSTEM

Week 11

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Functions:

1. Digestion

 ± Motility ± movement of food through the digestive tract by: Ingestion

Mastication

Degulation ± swallowing

Peristalsis

 ± Secretion

Exocrine ± water, HCL acid, bicarbonate

Endocrine ± hormones that regulate the digestive system

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2.  Absorption

 ± The process of digested foods transportedacross the wall of the small intestine into the

blood and lymph.

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ANATOMY

Mouth

Pharynx Esophagus

Stomach

Small intestine

Large intestine Rectum

 Anus

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Figure 16.1

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Divided into 2 main structur al areas:

Tubular gastrointestinal tract ± approximately

9m long and extends from mouth to anus

 Accessory organs ± teeth, tongue, salivary

glands, liver, gallbladder, pancreas

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DIGESTIVE SYSTEM ACTIVITIES

Ingestion of food into the mouth

Movement of food along the digestive tract

Mechanical preparation of food for digestion

Chemical digestion of food

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 Absorption of food

 Absorption of digested food into the

circulatory and lymphatic system

Elimination of indigestible substances and

waste products from the body by defecation

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The Or al Cavity

Functions of the Tongue ± Mechanical processing of food

 ± Manipulation to assist chewing and

swallowing

 ± Sensory analysis (taste, texture)

 ± Participation in speech

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

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The Or al Cavity

Salivary Glands

 ± Three pairs of glands ± Functions of saliva

Lubricates, cleanses oral cavity

Dissolves chemicals

Suppresses bacterial growth

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

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The Or al Cavity

Teeth

 ± Participate in mastication of food

 ± 20 deciduous teeth (³baby teeth´)

 ± 32 secondary teeth (³adult teeth´)

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

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Teeth: Structural Components and Dental

Succession

Figure 16-6(c)

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The Pharynx

Functions of the Pharynx

 ± Common passageway for 

food, drink, and air 

Digestive MoviePLA Y

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

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ESOPHAGUS

Portion of the GI tract connecting the

pharynx to the stomach.

Collapsible muscular tube.

 Approximately 25cm long.

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Figure 16.8a

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The stomach provides for the physical

breakdown of food that must precede chemicaldigestion.

Initiate digestion of proteins (CHO continues

from mouth but fats not digested here)

Kill bacteria with the strong acidity of gastric juice

STOMACH - Functions

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Functions Continued

Move food into the SI as a pasty material =

chyme. Only substances that can be absorbed and

digested in the stomach are alcohol and

aspirin

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The Small Intestine

Digestion in the Small Intestine

 ± Most digestion and absorption occurs in the small intestine ± Digestive enzymes and buffers are released by:

Pancreas

Liver 

Gall bladder 

 Approximately 7 metres long

Food takes 4 hours to travel through the small

intestine

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

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Figure 16.10

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The Large Intestine

Overview of the Large Intestine

 ± Reabsorbs water and electrolytes

 ± Compacts feces

 ±  Absorbs vitamins (K, biotin, and B5) made by

bacteria

 ± Stores faeces before defecation

1.2 metres long

Food takes 12-18 hours to travel through

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

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OTHER RELATED

STRUCTURES

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Pancreas

Produces pancreatic juice, an exocrinesecretion containing bicarbonate andimportant digestive enzymes that is passed

into the duodenum via the pancreatic duct.

Insulin and glycogen regulator 

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The Liver 

Functions of the Liver 

 ± Metabolic regulation Store absorbed nutrients, vitamins

Release nutrients as needed

 ± Hematological regulation

Plasma protein production

Remove old RBCs

 ± Production of bile

Required for fat breakdown

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

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The Liver 

The Surface

 Anatomy of the Liver 

Figure 16-14(a)

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The Liver 

Figure 16-14(b)

The Surface Anatomy of the Liver 

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GALL BLADDER

Stores and concentrates bile

Bile contains:

 ± Salts, bilirubin, cholesterol and other compounds

Bile is ejected into the duodenum.

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Digestion and Absorption

Processing and Absorption of Nutrients

 ± Two Steps in Processing M echanical 

Chemical 

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

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Digestion and Absorption

Processing and Absorption of Nutrients

 ± Carbohydrates

Starches are broken down by amylases

 ± Results in di- and trisaccharides

Enzymes on cell surface split them to monosaccharides

 Absorbed by the walls of intestine

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

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The Digestion and Absorption of Carbohydrates

Figure 16-18(a) (1 of 2)

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Figure 16-18(a) (2 of 2)

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Digestion and Absorption 

Processing and Absorption of Fats

 ± Bile emulsifies fats to small droplets

 ± Lipase hydrolyzes triglycerides into fatty acids

and monoglycerides

 ± Lipids diffuse into cells of intestinal wall

 ± Triglycerides are reformed

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

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The Digestion and Absorption of Lipids

Figure 16-18(b) (1 of 2)

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Figure 16-18(b) (2 of 2)

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Digestion and Absorption 

Processing and Absorption of Nutrients

 ± Proteins Breakdown starts in stomach

 ± Pepsin and HCl produce fragments

Breakdown continues in small intestine

 ± Pancreatic proteases produce small peptides

 ± Peptidases releases amino acids

Intestinal wall absorbs amino acids into the body

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

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The Digestion and Absorption of Proteins

Figure 16-18(c) (1 of 2)

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Figure 16-18(c) (2 of 2)

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Digestion and Absorption 

Water and Electrolyte Absorption

 ±  About nine liters/day enter the digestive tract Two liters of ingested water 

Seven liters of watery secretions

 ± Ions are absorbed by many mechanisms

Sodium, calcium, chloride, bicarbonate ±  All but about 150 ml is absorbed by osmosis, as

water ³follows´ the ions

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

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Digestion and Absorption 

 Absorption of Vitamins

 ± Fat-soluble vitamins combine with lipidsfor absorption

 ± Water -soluble vitamins diffuse across

the digestive epithelium

Exception: vitamin B12

requires intrinsic factor (from the gastric mucosa) for absorption

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

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Aging and the Digestive System

 Age-Related Changes in the Digestive

System

 ± Thinner, more fragile epithelium

 ± Reduced epithelial stem cell division

 ± Weaker peristaltic contraction Reduced smooth muscle tone

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

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DIGESTIVE SYSTEMS IMPORTANCE IN 

EXERCISE

Helps to digest and store fuel important for 

muscle contraction Breaks down food to fuel resynthesis of ATP

( fuel used to power mitochondria)


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