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BioIndustrial Partnership of Minnesota
Environmental Initiative Chemicals Regulation Working
Group July 20, 2011
Project Sponsors
Enriching Minnesota’s Future through the Biosciences
Agenda • Introduction
• Project Overview
• Biorefinery Development
• Agriculture-based opportunities
• Downstream market Development
Enriching Minnesota’s Future through the Biosciences
Food
Renewable Energy
Renewable Materials
Medical Devices
Biologics/Biopharma
Animal Health
The BioBusiness Alliance of Minnesota • Industry led, non-profit organization
• Partners with industry, academia and economic development groups to stimulate growth in Minnesota
• Supports growth in six targeted industries
Enriching Minnesota’s Future through the Biosciences
• LifeScience Alley
Largest state-based trade association focused on serving the life sciences industry.
Project Partners • Great Plains Institute
Enriching Minnesota’s Future through the Biosciences
Non-partisan, non-profit corporation based in Minneapolis Mission: to accelerate the transition to a sustainable, prosperous, low-carbon economy.
Enriching Minnesota’s Future through the Biosciences
Renewable Materials Value Chain Overview
Farmers/Foresters Biorefinery Development
Chemicals Industry- Formulators
End Product Manufacturing
Retail, End Uses
D2025 Recommendations
Renewable Materials
• Support market development efforts for the renewable materials value chain
» Renewable Materials Summit: Emerging Markets in the Upper Midwest
• Position Minnesota as a world leader in biorefinery operations
Enriching Minnesota’s Future through the Biosciences
Farmers/Foresters Biorefinery Chemical Industry-
Formulators End Product
Manufacturing Retail, End Uses
Liquid Fuels Markets
Project Description
The BioIndustrial Partnership of MN • Hypothesis: The industry is commercializing
technologies, and there are enough companies forming that any MN biorefinery could find a partner to enter the industry.
• Expected Implementation Actions:
» Education of business and community leaders.
» Identify assets and market MN to external partners.
» Policy development. • Regulatory issues.
• Financial assistance.
Enriching Minnesota’s Future through the Biosciences
Project Methodology • Q2 2011: Project Definition
» Assemble Core Team and develop clear understanding of industry
• Q3 2011: Community Dialogue
» Share global trends and gather information
• Q4 2011: Publication
» Minnesota Roadmap for BioIndustrial Development
• 2012: Education and Implementation
» Act on strategic direction
Enriching Minnesota’s Future through the Biosciences
Core Team • ~21 Members across value chain
» Biochemical companies
» Ethanol General Managers
» Engineering/Design Firms
» Legal and Financial Service Providers
» Government
• Industry Dominated
Enriching Minnesota’s Future through the Biosciences
Building an industry…
Enriching Minnesota’s Future through the Biosciences
Technology
$ $
Policy
Feedstock Off-take
Roadmap Preview
Roadmap Outline • Biorefinery Development
• Trends • Opportunities • Strategic Direction
• Downstream Market Development » Chemicals » Fuels
• Trends • Opportunities • Strategic Direction
• Agricultural-based Supply Chain Partnerships • Trends • Opportunities • Strategic Direction
• Forest-based Supply Chain Partnerships • Trends • Opportunities • Strategic Direction
• Policy Analysis and Recommendations
End Product Manufacturing Retail, End Uses Chemicals Industry-
Formulators
Biorefinery
Farmers/Foresters
Farmers/Foresters
Biorefinery
Biorefinery
Enriching Minnesota’s Future through the Biosciences
Biorefinery Development
Farmers/Foresters Biorefinery Chemical Industry-
Formulators End Product
Manufacturing Retail, End Uses
Liquid Fuels Markets
Integrated Biorefinery
Food/Feed • DDGs • Nutraceuticals • Food grade oil
Fuels • Ethanol • Butanol • Drop-in fuels
Chemicals and
Plastics
• Materials • Additives • Solvents
Example: Bio Iso-butanol
Enriching Minnesota’s Future through the Biosciences
Drop-in Fuels
• Iso-butanol • Jet Fuel • Diesel • Gasoline
Chemicals and
Plastics • C4 Platform
Volatile and increasing fossil fuel prices
Source: ICIS; http://www.icis.com/Articles/2011/06/27/9471601/Bio-based-intermediates-will-reduce-price-volatility.html
The signals of momentum? • 8 IPO’s in the last year2
» Financial markets are supporting the industry
• Green chemistry sector lead MN in VC investments for Q2 2011
• Global biochemicals industry: $585 billion by 20301
» Up to 17% of global chemicals market
» 5-10% average annual growth
• 5 billion pounds of chemicals by ~20153
• RFS2: 22 billion gallons of advanced biofuels by 2022
1 http://www.icis.com/Articles/2010/06/21/9368973/biochemical-market-forecasts-suggest-strong-growth.html 2 http://biofuelsdigest.com/bdigest/2011/06/03/myriants-125m-ipo-the-complete-digest-analysis/ 3 PiperJaffray Analysis
New targets for bio-based chemicals • Innovation is enabling new commodity chemicals
» New to the world chemicals • Segetis’ Javelin Technology
• Reluceo’s XLK Polymer
» Improved access to existing chemicals • Succinic Acid
• Glucaric Acid
• “New” chemicals can depend on other innovations in the final products
» Risk for slower growth
» Without significant improvement in functionality, they may not have the critical mass to survive
Cargill Resins Minnetonka
Natureworks est. 1997, ~100 emp.
Minnetonka
Segetis Est. 2006, 30 emp.
Golden Valley
Reluceo Est. 2009
Golden Valley
XL Terra Est. 2009
Golden Valley
Draths Est. 2005, 20 emp. Okemos, Michigan
Pine River Petrochemicals
Est. ~2009.
Gevo Est. 2009, 50 emp.
Luverne, MN and CO
Green Harvest Technologies Est. 2007, 1 emp.
Bloomington
Elevance Est. 2004, 45 emp.
Chicago, IL
Cargill BioH Est. 2003, 35 emp.
Plymouth
Cargill Industrial Oils
Minnetonka
Currently not located in Minnesota
1980s - 1990s
1997 - 2004
2005 - 2009
2009 - 2011 BioAmber
Est. 2009 Plymouth
Rivertop Renewables
Est. 2010
Minnesota Biobased Materials Family Tree
Opportunities and Concerns • Opportunities
» Intermediate chemicals the key targets
» MN Strengths to build on: • Cluster of companies has developed in the state • Use the medical device industry as a proxy • Strong suite of service providers that understand and support the industry
• Concerns
» MN lacks experienced chemical industry executives
» Scale-up capital and speed
» Cost of regulatory compliance and toxicity testing can squelch innovation
Strategic Needs- BioIndustrial Manufacturing
• Assistance in financing through “valley of death”
» Government grants are difficult
» Lack of focused venture capital
» Other states are moving more aggressively to support the industry
• Regulatory issues
• University policies to encourage faculty start-ups
• More clean-tech incubators in the state
Enriching Minnesota’s Future through the Biosciences
Agriculture Opportunities
Farmers/Foresters Biorefinery Chemical Industry-
Formulators End Product
Manufacturing Retail, End Uses
Liquid Fuels Markets
Agricultural-based Supply Chain
Enriching Minnesota’s Future through the Biosciences
• Biorefinery Development • Trends • Opportunities • Strategic Direction
• Downstream Market Development » Chemicals » Fuels
• Trends • Opportunities • Strategic Direction
• Agricultural-based Supply Chain Partnerships • Trends • Opportunities • Strategic Direction
• Forest-based Supply Chain Partnerships • Trends • Opportunities • Strategic Direction
• Policy Analysis and Recommendations
Farmers/Foresters Biorefinery
Agriculture Biorefineries
Enriching Minnesota’s Future through the Biosciences
End Market Development
Farmers/Foresters Biorefinery Chemical Industry-
Formulators End Product
Manufacturing Retail, End Uses
Liquid Fuels Markets
Downstream Market Development
Enriching Minnesota’s Future through the Biosciences
• Biorefinery Development • Trends • Opportunities • Strategic Direction
• Downstream Market Development » Chemicals » Fuels
• Trends • Opportunities • Strategic Direction
• Agricultural-based Supply Chain Partnerships • Trends • Opportunities • Strategic Direction
• Forest-based Supply Chain Partnerships • Trends • Opportunities • Strategic Direction
• Policy Analysis and Recommendations
End Product Manufacturing Retail, End Uses Chemicals Industry-
Formulators
Liquid Fuels Markets
Proposal for coordination
• Targeted discussions on regulatory impacts
• Perspectives and ideas to grow the industry
• Participate in implementation efforts
Enriching Minnesota’s Future through the Biosciences
Biofuels becoming biochemicals companies.
• Replace the entire barrel of oil
Source: Peter Keeling. Center For Biorenewable Chemicals