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Program

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world conference on regenerative medicine [Germany | Leipzig 2011 | November 2–4, 2011]

organizing institutions

suPPorted by

Partners

02 World Conference on Regenerative Medicine, November 2–4, 2011

F r a u n h o F e r I n s t I t u t e F o r C e l l t h e r a p y a n d I m m u n o l o g y I Z I

We transfer biomedical research into the clinic

The Fraunhofer Institute for Cell Therapy and Immunology IZI investigates and develops solutions to specific problems at the interfaces of medicine, life sciences and engineering.

The Institute develops, optimizes and validates methods and products for the Business Units Drugs, Cell Therapy, Diagnostics and Biobanks.

To our clients and partners from the pharmaceutical, biotechnological and medical technology industry, diagnostic laboratories, clinical units and research facilities we offer complete solutions ranging from market studies right down to the development of a market-ready product and its marketing authorization.

www.wcrm-leipzig.com \\ 03

table of Contents

table of Contents

Welcome Address 05

Advisory Board 07

Overview Conference Venue 08

Program

Program at a Glance 10

Wednesday, November 2, 2011 12

Thursday, November 3, 2011 20

Friday, November 4, 2011 32

Special: Veterinary Medicine Program 44

Fraunhofer Life Science Symposium 47

Poster Presentation

Overview Poster Exhibition 51

Posters 52

Evening Functions 67

Exhibitors 70

Media Partners 72

Partners and Sponsors 72

Endorsing Partners 75

Special: Companies in Saxony 77

General Information 81

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welCome address

Prof. Dr. Annette SchAvAn

Regenerative medicine is one of the most promising fields of biomedical research. By mobilizing the human body’s self-healing powers, it offers hope for many patients with diseases or injuries that were previously

difficult or even impossible to treat. Moreover, we expect regenerative medicine to provide new ways of compensating for deteriorating organ function in age-related diseases. This is particularly important against the backdrop of demographic change and the scarcity of donor organs. Regeneration technologies also have the potential to advance the development of testing methods for the pharmaceutical and chemical industries in order to establish alternatives to animal experiments.

Gentle and lasting healing – that is the strategy of regenerative medicine, and of the researchers working in this field in science and industry around the world. The World Conference on Regenerative Medicine 2011 in Leipzig offers researchers an opportunity to exchange views on the latest developments. Meetings of this kind are becoming increasingly important in such rapidly growing and interdisciplinary fields as regenerative medicine. They are another sign that Germany has become an internationally recognized leader in the field of regenerative medicine. Researchers at universities and hos-pitals and the numerous small and medium-sized companies operating in the fields of

biotechnology and medical technology have made a significant contribution to this.

The Federal Government has been supporting this development since the late 1990s by invest ing in basic and application-oriented research in science and industry. Between 1999 and 2007 alone, the Federal Ministry of Education and Research earmarked more than 60 million euros for funding initiatives in areas such as stem cell research, cell-based therapies, and tissue engineer ing. Moreover, funding is being provid ed for Translational Centres in Berlin, Leipzig, Hanover, Dresden, Tübingen/Reutlingen, Rostock and Heidelberg.

We are strengthening the networking of German research locations with experts from around the world through joint international calls for proposals. We want to ensure that scientific findings do not just lead to high-level publications, but that patients benefit from the achievements of regenerative medicine as well.

I would like to thank the organizers of the World Conference on Regenerative Medicine 2011 – the Translational Centre for Regenerative Medicine and the Fraunhofer Institute for Cell Therapy and Immunology – for their hard work. I hope that this conference gives all participants an opportunity to engage in a lively exchange of ideas and to gain new insights that will benefit patients.

Prof. Dr. Annette Schavan, MdBFederal Minister of Education and Research


welCome addresses

Bringing together ex-perts from the diverse and interdisciplinary branches that focus on regenerative medi-cine is one main goal of the World Con-ference on Regenera-tive Medicine 2011. Cooperation between basic research, en-

gineering and clinical medicine is a prerequisite for realization of new treatment and therapy approaches for degenerative diseases. Solu-tions to the problems provided by each of the involved parties must be integrated to answer the following questions: Which underlying cell mechanisms must be considered? How can damaged tissue be reconstituted? Which legal hurdles exist prior to market launch of regenera-tive medicine products? The World Conference on Regenerative Medicine has succeeded in combining the different disciplines of regenera-tive medicine. Consequently, a rapidly growing number of participants from many disciplines attend World Conference on Regenerative Medicine which meanwhile has become one of Europe´s largest and most interdisciplinary conferences in this field.

welCome address

Prof. Dr. frAnk emmrich

The backdrop for the World Conference on Regenerative Medicine 2011, which takes place 02–04 November, is the city of Leipzig. The conference is organized by the European and International networks of Regenerative Medicine together with numerous scientific societies coordinated by the regional hosts namely the Fraunhofer Institute for Cell Therapy and Immunology and the Translational Centre for Regenerative Medicine of the University of Leipzig. Following the establishment of Leipzig as international location for regenerative medicine, the organizers intend to continue this successful tradition in 2013.

In addition to its excellent biotechnological and medical infrastructure, Leipzig has the charm to make your stay a unique experience. Discover the famous old city centre with the famous St. Thomas Church, the distinctive old city hall, awesome passages and take a look at the new emerging university building. I am delighted to welcome you to Leipzig and wish all of us interesting days with top-class, beneficial presentations and lasting impressions of both the conference and Leipzig. I hope the World Conference on Regenerative Medicine 2011 will facilitate diverse cooperation and open new horizons between clinicians, industry and researchers active in the field of regenerative medicine.

Prof. Dr. Frank EmmrichConference President


Translational Centre for Regenerative Medicine (TRM) Leipzig

Translational Research

Research Services

Educational Services

The Translational Centre for Regenerative Medicine (TRM) of the Universität Leipzig was founded with the mission to efficiently translate research results of regenerative medicine into clinical application.

Currently the TRM Leipzig supports eight basic research teams, sixteen teams in the preclinical phase and three teams conducting clinical trials.

Research Areas and Key Technologies• TissueEngineeringand

MaterialsScience• CellTherapiesforRepairand

Replacement• RegulatoryMoleculesand

DeliverySystems• Imaging,Modellingand

MonitoringofRegeneration

Research Services• QualityManagement• CellAuthentication• ImageProcessing• MicrosurgeryandAnimalModels

TRM LeipzigPhilipp-Rosenthal-Str. 5504103 LeipzigGermany

Tel: +49 341 9739600Email: [email protected]

Anzeige WRM-Heft2011_V4.indd 1 30.09.11 09:18


information

advisory board

Keynote sPeaKers

Buckler, Lee R., Cell Therapy Group – REGENMED INDUSTRY CONSULTING, Langley,

Canada \\ Dhein, Stefan, Universität Leipzig, Clinic for Heart Surgery, Leipzig,

Germany \\ Emmrich, Frank, Fraunhofer Institute for Cell Therapy and Immunology

IZI and Translational Centre for Regenerative Medicine (TRM), Leipzig, Germany \\ Haverich, Axel, Hannover Medical School, REBIRTH – Cluster of Excellence, Hannover,

Germany \\ Hutmacher, Dietmar W., Queensland University of Technology, Brisbane,

Australia \\ Kohler, Konrad, Universität Tübingen, Center for Regenerative Biology

and Regenerative Medicine, Tübingen, Germany \\ Magin, Thomas, Universität

Leipzig, Translational Centre for Regenerative Medicine, Leipzig, Germany \\ Mason, Chris, University College London, Advanced Centre for Biochemical Engineer-

ing, London, UK \\ Meisel, Hans-Jörg, BG-Clinic Bergmannstrost, Department

of Neurosurgery, Halle, Germany \\ Skutella, Thomas, University of Heidelberg,

Institute for Anatomy and Cell Biology, Heidelberg, Germany \\ Walles, Heike,

Julius-Maximilian-Universität Würzburg, Chair for Regenerative Medicine, Würzburg

Allsopp, Tim, UK \\ Blunn, Gordon, UK \\ Bondue, Antoine, Belgium \\ Breuer, Christopher Kane, USA \\ Bulte, Jeff, USA \\ Burdick, Jason A., USA \\ Clevers, Hans, The Netherlands \\ De Luca, Michele, Italy \\ Edinger, Matthias,

Germany \\ Goodship, Allen, UK \\ Grüll, Holger, The Netherlands \\ Guest, Debbie, UK \\ Gulino, Alberto, Italy \\ Hengstler, Jan G., Germany \\ Hescheler, Jürgen, Germany \\ Horwitz, Edwin M., USA \\ Kasashima, Yoshinori, Japan \\ Krause, Karl-Heinz, Switzerland \\ Klemm, Dieter, Germany \\ Kriegstein, Arnold, USA \\ Lendlein, Andreas,

Germany \\ Martin, Ivan, Switzerland \\ Mason, Chris, UK \\ Nagy, Andras,

Canada \\ Niklason, Laura E., USA \\ Nobert, Karl, USA \\ Powers, Linda,

USA \\ Rankin, Sara, UK \\ Razvi, Enal, UK \\ Sawitzki, Birgit, Germany \\ Schultze, Joachim L., Germany \\ Siegel, Bernard, USA \\ Smith, Roger, UK \\ Steinhoff, Gustav, Germany \\ Steinkasserer, Alexander, Germany \\ Tanaka,

Elly M., Germany \\ Torres, Art, USA \\ van Weeren, René, The Netherlands \\ Vidal, Martin, USA \\ Voss, Thorsten, Germany \\ Walles, Heike, Germany \\ Widschwendter, Martin, UK \\ Zhang, Kun, USA


Floor -1

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Hall 2 Hall 3 Hall 4 Hall 5 Room 11

Wednesday, Nov 2, 2011

11:00 am–12:30 pm Signalling & Cancer Vascular Engineering IVRMS I

12:30–02:00 pm Lunch Break

02:00–03:30 pm Adult Stem Cell Sources Cardiac Engineering PhD Session I

03:30–04:00 pm Coffee Break

04:00–05:30 pm Bone & Cartilage Engineering I In Vitro Models In Vivo Models

05:30 pm Opening Ceremony (Hall 1) and Get-together (Exhibition Area)

Thursday, Nov 3, 2011

09:00–10:30 am Bone & Cartilage Engineering II

Surfaces & Cell-Material Interaction

Biomarker Allogenic Cell Therapy

10:30–11:00 am Coffee Break

11:00 am–12:30 pm Bioreactor Technology Scaffolds Commercialization Strategies I

Advances in Measure-ment and Imaging for Regenerative Medicine

Open Access – The Future of Scientific Publishing


02:00–03:30 pm Stem Cells and Regeneration of Neuronal Disordes

Biomaterials & Scaffolds Regulatory, Legal & Ethical Issues I

PhD Session II Attune® Acoustic focusing cytometer – Precision & Sensitivity at All Speeds for Rare Event Detection and Precious Samples


04:00–05:30 pm Skin & Soft Tissue Regeneration

Biomedical Materials & Implants

Immunological As-pects of Regeneration

Regulatory Affairs

05:30 pm Poster Party (Poster Exhibition Area Floor 0)

Friday, Nov 4, 2011

09:00–10:30 am Cell Therapy Liver, Lung & Kidney Regeneration

Toxicity & Safety Anti-Inflammation & Tissue Regeneration

PhD Session III


11:00 am–12:30 pm Reprogramming, Epi genomics & Cell Fate

Stem Cell Differentiation Hematopoietic Cell Therapy

Manufacturing Cell Products


02:00–03:30 pm Induced Pluripotent Stem Cells

Nerve & Spinal Cord Regeneration

Regulatory, Legal & Ethical Issues II

Cell Tracking & Imaging


04:00–05:30 pm Embryonic Stem Cells Bone & Cartilage Engineering III

Commercialization Strategies II

IVRMS II

06:30 pm Social Evening: Tropical Experience World Gondwanaland

Program at a glanCe


Program


Wednesday, Nov 2, 2011

11:00 am–12:30 pm Signalling & Cancer Vascular Engineering IVRMS I


02:00–03:30 pm Adult Stem Cell Sources Cardiac Engineering PhD Session I


04:00–05:30 pm Bone & Cartilage Engineering I In Vitro Models In Vivo Models


Thursday, Nov 3, 2011

09:00–10:30 am Bone & Cartilage Engineering II


Biomarker Allogenic Cell Therapy


11:00 am–12:30 pm Bioreactor Technology Scaffolds Commercialization Strategies I

Advances in Measure-ment and Imaging for Regenerative Medicine



02:00–03:30 pm Stem Cells and Regeneration of Neuronal Disordes

Biomaterials & Scaffolds Regulatory, Legal & Ethical Issues I

PhD Session II Attune® Acoustic focusing cytometer – Precision & Sensitivity at All Speeds for Rare Event Detection and Precious Samples


04:00–05:30 pm Skin & Soft Tissue Regeneration


Immunological As-pects of Regeneration

Regulatory Affairs


Friday, Nov 4, 2011

09:00–10:30 am Cell Therapy Liver, Lung & Kidney Regeneration

Toxicity & Safety Anti-Inflammation & Tissue Regeneration

PhD Session III


11:00 am–12:30 pm Reprogramming, Epi genomics & Cell Fate

Stem Cell Differentiation Hematopoietic Cell Therapy



02:00–03:30 pm Induced Pluripotent Stem Cells

Nerve & Spinal Cord Regeneration




04:00–05:30 pm Embryonic Stem Cells Bone & Cartilage Engineering III

Commercialization Strategies II

IVRMS II



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Hall 3 Hall 4 Hall 5

11:00 am–12:30 pm

Signalling & Cancer

* Clevers HC

* Gulino A

Vascular Engineering

* Breuer CKIVRMS I

* Goodship A

* Rankin S

* Nobert K

* van Weeren R

12:30–02:00 pm

Lunch Break

02:00–03:30 pm

Adult Stem Cell Sources Cardiac Engineering

* Steinhoff GPhD Session I

03:30–04:00 pm

Coffee Break

04:00–05:30 pm

Bone & Cartilage Engineering I

* Blunn G

In Vitro Models In Vivo Models

* Tanaka EM


* Keynote speaker

Program overview

WeDneSDAy, november 2, 2011



Program

Program in detail

11:00 am–12:30 pm

Signalling & Cancer ► Hall 3

Chairs: Aust G, Clevers HC

Lgr5 stem cells in self-renewal and cancer

* Keynote: Clevers HC

Neural stem cells control by the morphogen Hedgehog

* Keynote: Gulino A

Synergistic effect of lenalidomide and dendritic cell vaccination on cancer

immunotherapy

Lee JJ

Autologous dendritic cells pulsed with recombinant human fusion protein

[mucin 1-glutathione S-transferase] coupled to oxidized polymannose as mainte-

nence treatment of epithelial ovarian cancer in remission: A clinical trial update

Lehman M, Prima BioMed Ltd.

Vascular Engineering ► Hall 4

Chairs: Dhein S, Breuer CK

Tissue engineered vascular grafts: From the bench to the bedside and back again

* Keynote: Breuer CK

Additive manufacturing of an artificial blood vessel system by the combination

of inkjet-printing and two-photon polymerization

Engelhardt S

Detergent-based decellularization procedure reduces but not eliminates cellular

proteins in equine carotide arteries: Implications for immunogenicity

Böer U


Co-culture spheroids as a tool for angiogenic research

Metzger W

Electrospun biodegradable materials for vascular regenerative medicine

Damiano G

IVRMS I ► Hall 5

Chairs: Brehm W, Ribitsch I

organized by the International Veterinary Regenerative Medicine Society

Veterinary regenerative medicine – Past, present and future clinical applications

* Keynote: Goodship A

Endogenous release of stem cells

* Keynote: Rankin S

Regulatory affairs for stem cell use in veterinary medicine

* Keynote: Nobert K

The potential of (hybrid) scaffolds for the treatment of orthopaedic disease

* Keynote: van Weeren R




Program

02:00–03:30 pm

Adult Stem Cell Sources ► Hall 3

Chair: Metzger M

Transplantation of a newly developed human fetal endothelial cells accelerate

functional recovery in an experimental stroke model

Lee MC

Lineage tracing of adult stem cells in murine heart

Uchida S

Extracting stem cells and surrounding chaperon cells from the zone of Ranvier

out of non-decalcified rabbit knee

Richter H, ROWIAK GmbH

Age-dependent characterization of fibroblasts isolated from human anterior

cruciate ligament

Prager P

Immune modulatory properties of equine umbilical cord blood, bone marrow

and adipose tissue-derived MSCs in vitro

Koch T

Transplantation of human adult enteric neural progenitors into mouse colon

after experimental ablation of the enteric plexus in vivo

Hetz S

Cardiac Engineering ► Hall 4

Chairs: Dhein S, Steinhoff G

Update on cardiac stem cell therapy

* Keynote: Steinhoff G

C-kit+ subpopulations display different proliferation potential and occurrence

in heart of young and aged mice

Mark P


Prospects on the use of stem cells obtained from peripheral blood in

degenerative myocardial pathologies

Cagni G

Matrigel could recruit stem cells for cardiac regeneration

Li W

Bioengineering of the embryonic cardiovascular progenitor cell niche

Schenke-Layland K

PhD Session I ► Hall 5

Chair: Hescheler J

Isolation and maintenance of human adipose stem cells avoiding animal-origin

reagents

Escobedo-Lucea C

VSEL cells are not pluripotent but contain mesenchymal precursors

Heider A

Economic, defined and xeno-free large-scale cryopreservation of HESC with

vegetal hydrolysates for clinical applications

T‘Joen V

Development of embryonic stem cell derived neuronal networks for the

microelectrode array based analysis of network activity

te Kamp V

Micro RNAs influence the generation of induced plurpotent stem cells and

subsequent differentiation into the pancreatic lineage

Jung M

Investigation of pathogenesis of Parkinson´s disease by PD patients derived-

induced pluripotent stem cells

Liao MC




Program

04:00–05:30 pm

Bone & Cartilage Engineering I ► Hall 3

Chairs: Schulz R, Blunn G

The interface between regeneration, reconstruction and replacement for bone

and joints

* Keynote: Blunn G

Stem cell based repair of a focal cartilage defect in an ovine model – Longterm

results of a double-blinded randomized trial

Marquass B

Articular cartilage repair using collagen type I hydrogels

Nöth U

The use of poly(L-lactide-co-caprolactone) as a scaffold for adipose stem cells in

bone tissue engineering: Application in a spinal fusion model

Vergroesen PP

In Vitro Models ► Hall 4

Chair: Peters M

Hypoxia changes main characteristics of human bone marrow-derived

mesenchymal stromal cells in vitro

Wobus M

Drug discovery for neurological disorders: A novel 3D in vitro Alzheimer´s

disease model

Krinke D

Every cell counts – Quantification of the reepithelialization process in human

wound healing

Westphal K; Safferling K

Human hair follicle equivalents in vitro for transplantation and substance testing

Ataç B


3D spheroids of adipose-derived stem cells as building blocks for adipose tissue

regeneration

Blunk T

Loss of Dnd1 facilitates the cultivation of genital ridge-derived rat embryonic

germ cells

Zschemisch NH

In Vivo Models ► Hall 5

Chairs: Tanaka EM, Wagner DC

Multilineage regeneration in the amphibian limbs: A tale of different tissues

* Keynote: Tanaka EM

Inflammatory response and apoptotic cell death in injured zebrafish spinal cord

Hui SP

Large animal model (swine) for cell-based cardiovascular repair in acute

myocardial infarction: One year follow up

Crovace A

Inner ear rehabilitation in the deafened cochlea of NOD-SCID mice following

transplantation of human pluripotent mesenchymal stem cells

Revoltella RP

Sweat gland-derived stem cells improve vascularization in scaffold-based

dermal regeneration

Danner S



Program

05:30 pm

Opening Ceremony ► Hall 1

Welcome adresses

\\ Dr. Helge Braun, MdB

(Parliamentary State Secretary, Federal Ministry of Education and Research)

\\ Prof. Dr. Dr. Sabine von Schorlemer

(State Minister, Saxon State Ministry for Science and the Arts)

\\ Uwe Albrecht

(Deputy Mayor for Economic Affairs and Employment, City of Leipzig)

\\ Prof. Dr. Beate A. Schücking

(Rector of the Universität Leipzig)

\\ Prof. Dr. Frank Emmrich

(Conference President, Director Fraunhofer Institute for Cell Therapy and Immunology

and Translational Centre for Regenerative Medicine Leipzig)

Musical interlude “Neue Musik Leipzig“ (New Music Leipzig)

Overview of the California Institute for Regenerative Medicine (CIRM)

Senator Art Torres, (Ret.) (Vice-Chair of the Governing Board of the CIRM)

07:00 pm

Get-together ► Exhibition Area


\\ Program overview

thurSDAy, november 3, 2011


09:00–10:30 am

Bone & Cartilage Engineer-ing II


* Burdick JA

Biomarker

* Schultze JL

* Widschwend- ter M

* Grüll H

* Voss T

Allogenic Cell Therapy

10:30–11:00 am

Coffee Break

11:00 am–12:30 pm

Bioreactor Technology

* Walles H

Scaffolds Commercializa-tion Strategies I

* Powers L

* Razvi E

Advances in Measurement and Imaging for Regenera-tive Medicine


12:30–02:00 pm

Lunch Break

02:00–03:30 pm

Stem Cells and Rege-neration of Neuronal Disordes

* Krause KH

Biomate-rials & Scaffolds

* Lendlein A

Regulatory, Legal & Ethical Issues I

PhD Session II Attune® Acoustic Focusing Cytome-ter – Precision & Sensitivity at All Speeds for Rare Event Detection and Precious Samples

03:30–04:00 pm

Coffee Break

04:00–05:30 pm

Skin & Soft Tissue Rege-neration

* De Luca M


* Klemm D

Immunological Aspects of Regeneration

* Steinkasserer A

* Sawitzki B

Regulatory Affairs


* Keynote speaker


Program


Program in detail

09:00–10:30 am

Bone & Cartilage Engineering II ► Hall 2

Chair: Meisel HJ

Keeping up the pace of bone regeneration: What can we learn by comparing

giants with miniatures?

Tryfonidou M

Mechanostimulation reverses the catabolic phenotype of human osteoarthritic

matrix-embedded chondrocyts – A preliminary report

Halbwirth F

Optimization of tissue engineering constructs using jaw periosteal cells

Alexander D

3D multilayered co-culture system for investigating chondrogenesis in

mesenchymal stem cells

Millan C

Simplet (smp) is required for regeneration and beta-catenin-dependent Wnt

signal transduction

Antos C

Effect of sinusoidal loading frequencies on calcification of tissue-engineered

bone in vitro

Koaykul C

Surfaces & Cell-Material Interaction ► Hall 3

Chair: Francke M

Engineering biomaterial design to control stem cell interactions

* Keynote: Burdick JA

Cell morphometric analysis of osteoblasts on geometrically microstructured

titanium surfaces – Basic research for orthopedic implants

Matschegewski C


Modulation of inflammatory macrophage functions by artificial extracellular

matrices used as biomaterial coatings

Franz S

The enhanced modulation of key bone matrix components by modified

titanium implant surfaces

Brett P

Electrospun collagen II and (poly-epsilon-caprolactone) co-polymer nanofibres

– Biomimetic scaffold design with chondro-inductive properties

Rackwitz L

Biomarker ► Hall 4

Chair: Schultze JL

Adaptive learning and simulation approaches enhance molecular diagnostics of

malignant and infectious diseases

* Keynote: Schultze JL

Epigenetics, stem cells and cancer

* Keynote: Widschwendter M

See, reach, treat: Biomarkers and imaging for diagnosis and treatment of

diseases

* Keynote: Grüll H

The better the source, the more to explore

* Keynote: Voss T


Program


Allogenic Cell Therapy ► Hall 5

Chair: Horwitz EM, President of ISCT and Chairman of Pluristem‘s Scientific Advisory Board

organized by Pluristem Therapeutics Inc.

Placental-derived adherent cells for the treatment of peripheral vascular

disease: FDA / EMA-approved phase I / IIa clinical trial

* Keynote: Horwitz EM

PLX cells for the treatment of irradiation exposure

* Keynote: Gorodetsky R

The biology of mesenchymal-like adherent stromal cells, cultured in 3D

scaffolds

Speaker: Abraham E


11:00 am–12:30 pm

Bioreactor Technology ► Hall 2

Chairs: Christ B, Walles H

Bioreactor technology and automatization in the production of human 3D

tissues

* Keynote: Walles H

Mass expansion of human pluripotent stem cells (hPSC) in controlled, stirred

bioreactors

Zweigerdt R

Development of a bioreactor for the in vitro culture of bone tissue supported

by computer fluid simulations

Kahlig A


A novel animal component free surface for growth of stem cells and other

fastidious cells

Marwood T, Thermo Fisher Scientific

Osteogenic differentiation of mesenchymal stem cells under controlled and

reproducible conditions in two parallel perfusion bioreactors

Kress S

Scaffolds ► Hall 3

Chair: Simon J

organized by Transregio TRR 67

Introduction to the Transregio matrix engineering

Simon J

Artificial extracellular matrix composed of collagen I and sulphated glycosami-

noglycans induces a proliferative dermal fibroblast phenotype in vitro

van der Smissen A

Investigation of the interaction of interleukin-8 with hyaluronan, chondroitin

sulfate, dermatan sulfate, and their sulfated derivatives by fluorescence and

solution NMR spectroscopy and molecular modelling

Pichert A

Artificial extracellular matrices composed of collagen I and synthetic GAG

derivatives promote osteogenic differentiation of human mesenchymal stromal

cells

Hempel U

Enhancing osseointegration with addition of glycosaminoglycans to titanium

surfaces

Rammelt S


Program


Commercialization Strategies I ► Hall 4

Chair: Faber S

Stem cell products in development: Where is progress being made?

* Keynote: Powers L

Stem cells worldwide market snapshot

* Keynote: Razvi E

Advances in Measurement and Imaging for Regenerative Medicine ► Hall 5

Chair: Macdonald R

organized by PTB (national metrology institute)

Analysis of cell-surface interactions using 3D cell morphometry

Shaw M

Multi-parametric monitoring of cell quality in regenerative medicine products

Baradez MO

Assessment of measurement of cell confluency level by image analysis

Kummrow A

Chemical selective in vitro bio-assay for cells / EC matrix detection in 3D not-

labelled cell cultures

Sassi MP

Quantitative assessment of cell viability based on flow cytometry and microscopy

Frankowski M


Open Access – The Future of Scientific Publishing ► Room 11

organized by InTech – Open Access Publisher

Advantage of Open Access publishing in medicine

Rylett N

Author‘s perspective

t.b.a.

Round table discussion about Open Access in medicine

Bajic B


02:00–03:30 pm

Stem Cells and Regeneration of Neuronal Disordes ► Hall 2

Chairs: Krause KH, Peters M

Pluripotent stem cell-based therapy of Parkinson‘s disease

* Keynote: Krause KH

The grafted fetal neural progenitor cells can integrate in the adult hippocampal

tissue after ischemic injury

Butenko G

Direct conversion of fibroblast cells into tripotent neural stem cells

Edenhofer F

Cellular “functional replacement” with a “cell-free strategy” in early

Alzheimer‘s and Parkinson‘s diseases: Evidences from related animal models

Fernandez CI


Program


Biomaterials & Scaffolds ► Hall 3

Chairs: Jäger R, Lendlein A

Multifunctional biomaterials

* Keynote: Lendlein A

Scaffold mediated non-viral inhibition of collagen type I and type III in cardiac

fibroblasts

Monaghan M

Fabrication of scaffolds via two-photon polymerization and microreplication

techniques

Koroleva A

Cell behaviour on resorbable nonwovens composed of biodegradable

polyglycolic or polylactide acid for the cardiovascular tissue engineering

Lüders C

Regulatory, Legal & Ethical Issues I ► Hall 4

Chair: Siegel B

Pre-clinical efficacy and safety requirements for the approval of cell-based

medicinal products – Demonstration of the efficacy and safety testing concept

at Fraunhofer IZI and TRM Leipzig

Lehmann J, Schulz R

Stem cell research and banking: International perspectives

Isasi R

The search for new stem cell research rules between the poles of the recent

preimplantation genetic diagnosis sentence of the federal supreme court and

the impact of reprogrammed stem cells in Germany

Faltus T


Preparing the grounds: Setting standards to shape the business environment

for tommorrw´s market success of your innovative products for application in

regenerative medicine

Wenzelewski K

Medicinal feasibility “in bench to bedside projects“

Meisel HJ

PhD Session II ► Hall 5

Chair: Walles H

Infrapatellar fat pad as an alternative source of mesenchymal stem cells: New

strategies for cartilage tissue engineering

Lopa S

Improvement of cardiac function and restoration of beta-adrenergic

responsiveness in dilative cardiomyopathy by implantation of a novel cardiac

assist device (Engineered Heart Tissue) in a rat model

Schlegel F

Fabrication of tissue engineered fibrin based aortic heart valves with sinuses of

valsalva

Borgmann A

Revascularisation of skin grafts – Vascular transformations and proteolytic

activity

Knapik A

Mesenchymal stromal cells immobilized in an oriented 3D scaffold transiently

accelerate functional recovery after acute spinal cord injury

Montzka K


Program


Attune® Acoustic Focusing Cytometer – Precision & Sensitivity

at All Speeds for Rare Event Detection and Precious Samples ► Room 11

organized by Life Technologies GmbH

Attune® acoustic focusing cytometer – Precision & sensitivity at all speeds for

rare event detection and precious samples

Thompson R


04:00–05:30 pm

Skin & Soft Tissue Regeneration ► Hall 2

Chairs: De Luca M, Magin T

Limbal stem-cell therapy and long-term corneal regeneration

* Keynote: De Luca M

Outer root sheath melanocytes as a causal autologous therapy for vitiligo

Savkovic V

Update on ATMPs in veterinary medicine: From lab to patient´s site

Emmendörffer A, V-Care Biomedical GmbH

Cell minig offers a new autologous stem cell source residing in sweat glands for

skin regeneration of burns

Salem H

Target tissue-specific scaffold design for rotator cuff repair – The isotropy of

collagen I nanofibre scaffolds regulate the behaviour and tenogenic differentia-

tion of mesenchymal stem cells

Rackwitz L


Biomedical Materials & Implants ► Hall 3

Chairs: Klemm D, Mayr S

Nanocelluloses: Natural, biomimetic, and bioactive materials for applications as

patches and even as heart bypass

* Keynote: Klemm D, Jenpolymers Ltd.

Additive manufacturing of an artificial blood vessel system: Optimum lay-out

and fluid-mechanical characterization

Jäger R

Controlled biodegradation of PCL electrospun nanofiber-based scaffolds

Kim GM

Cell seeding of collagen scaffolds via cell printing

Glasmacher B

Modulation of hydrogel degradation guides endothelial cell morphogenesis

Chwalek K

Immunological Aspects of Regeneration ► Hall 4

Chairs: Sack U, Sawitzki B

Soluble CD83 modulates autoimmunity and promotes tolerance induction to

transplants

* Keynote: Steinkasserer A

How to target memory T cells and restore tolerance?

* Keynote: Sawitzki B

Extracorporeal cell-therapy of patients with septic shock using human donor

granulocytes

Mitzner S

Impact of engineered extracellular matrices on the immunomodulatory proper-

ties of mesenchymal stromal cells

Wehner R


Program


Regulatory Affairs ► Hall 5

Chair: Mazouz C, VP Clinical & Regulatory Affairs

organized by Pluristem Therapeutics Inc.

Transition from pre-clinical to clinical development; the devil is in the details

* Keynote: Bravery CA

Allogeneic cellular product candidate; case study “off the shelf” PLX cells

Speaker: Mazouz C

t.b.a.

Speaker: Balshüsemann D

t.b.a.

Speaker: Guenther C

05:30 pm

Poster Party ► Poster Exhibition Area

Discussion of the posters. Drinks and finger food will be served.

07:00 pm: Award ceremony for best abstract and best poster

Best Abstract and Best Poster Award kindly supported by Pluristem Therapeutics Inc.


\\ Program overview

friDAy, november 4, 2011


09:00–10:30 am

Cell Therapy

* Edinger MLiver, Lung & Kidney Regeneration

* Niklason LE

Toxicity & Safety

* Hengstler JG

Anti-Inflam-mation & Tissue Regeneration

PhD Session III

10:30–11:00 am

Coffee Break

11:00 am–12:30 pm

Reprogram-ming, Epi-genomics & Cell Fate

* Zhang K

Stem Cell Differentiation

* Bondue A

Hematopoietic Cell Therapy

* Horwitz EM


* Martin I

12:30–02:00 pm

Lunch Break

02:00–03:30 pm

Induced Pluri-potent Stem Cells

* Nagy A

Nerve & Spinal Cord Regene-ration

* Kriegstein A


* Siegel B


* Bulte J

* Kasashima Y

03:30–04:00 pm

Coffee Break

04:00–05:30 pm

Embryonic Stem Cells

* Hescheler J

* Guest D

Bone & Carti-lage Engineer-ing III

Commerciali-zation Strategies II

* Allsopp T

* Mason C

IVRMS II

* Smith R

* Vidal M

* Nixon AJ


* Keynote speaker


Program


Program in detail

09:00–10:30 am

Cell Therapy ► Hall 2

Chairs: Alt R, Edinger M

CD4+CD25+ regulatory T cells in allogeneic stem cell transplantation

* Keynote: Edinger M

Combining gene and cell therapy for stimulation of vascularisation in ischemic

skeletal muscle

Makarevich P

Local cytokine profile after autologous transplantation of muscle derived cells

into the skeletal muscle

Burdzinska A

Intra-articular administration of autologous platelet rich plasma for lameness

associated with fetlock arthritis: A case series

Mirza M

Liver, Lung & Kidney Regeneration ► Hall 3

Chairs: Christ B, Niklason LE

Lung regeneration: Progress and challenges

* Keynote: Niklason LE

Novel growth factor containing hydrogels to support tubular regeneration

after acute kidney injury

Tsurkan M

Characterization of decellularized lung tissue using vascular corrosion casting

Ouyang Y


Human kidney-derived cells cultured on small intestinal submucosa to generate

a renal proximal tubule model

Hoppensack A

Self-renewal factor Bmi1 is involved in adult hepatic progenitor cell prolifera-

tion and differentiation

Penning L

Toxicity & Safety ► Hall 4

Chairs: Hengstler JG, Lehman J

Cell alignment along micro-vessels as order principle to regenerate tissue

architecture: From experiment to virtual tissues and back

* Keynote: Hengstler JG

Neural cell transplantation in patients with neurodegenerative disorders:

In vitro validation and safety assessment

Moellers S

Evaluation of human MMSCs susceptibility to SiO2-based nanoparticles

Andreeva E

A new device for screening hepatotoxicity: Test results with the muscle

relaxant Rocuronium

Sauer M


Program


Anti-Inflammation & Tissue Regeneration ► Hall 5

Chair: Reinecke J

organized by ORTHOGEN Lab Services GmbH and ORTHOGEN Veterinary GmbH

Interest in regenerative medicine resurges. Where does it put PRP and ACS?

Reinecke J, Orthogen

Intralesional treatment of equine tendon lesions with platelet rich plasma (PRP)

and autologous conditioned serum (ACS)

Geburek F

Clinical and experimental evidence for tissue regeneration through autologous

conditioned serum

Moser C

PhD Session III ► Room 11

Chair: Mason C

Antigen processing is impaired in mouse pluripotent stem cell lines

Monecke S

Reconstruction of tracheal lessions by bioartificial tissue – From R&D to GMP

Dally I

Detection of collagen produced by live human corneal fibroblasts and human

mesenchymal stem cells cultured in 3D fibrin gel using label free non-invasive

imaging

Mortati L

Dermal fibroblasts display similar phenotypic and differentiation capacity to

fat-derived mesenchymal stem cells, but differ in anti-inflammatory and

angiogenic potential

Blasi A


Direct chemosensitivity testing using a novel biosensoric screening system for

the individualized therapy of the malignant melanoma

Pönick S

Topological effects of magnetic nanoparticles embedded in the polymeric

ultra-thin films for cardiac repair on cell adhesion and proliferation properties

Ventrelli L


11:00 am–12:30 pm

Reprogramming, Epigenomics & Cell Fate ► Hall 2

Chairs: Schröder I, Zhang K

The genomics and epigenomics of nuclear reprogramming

* Keynote: Zhang K

In vitro aging of human IPS derived fibroblasts

Arnold A

HMGA2 links self-renewal and senescence of mesenchymal stem cells via its

interaction with the CDKN2A-locus

Markowski D

Induced pluripotent stem cells for basic research and practical applications

Kiselev S


Program


Stem Cell Differentiation ► Hall 3

Chairs: Bondue A, Cross M

Defining MESP1 function during early cardiovascular progenitor specification

* Keynote: Bondue A

In vitro generation of pancreatic islet bodies from mouse embryonic stem cells

using a 3D differentiation model

Hommel A

Development of robust, scalable, and synthetic systems for the maintenance of

pluripotency and subsequent differentiation

McRae S, Cell Guidance Systems Ltd

Mesenchymal stromal cells from the amniochorionic membrane uf human term

placenta: Potential cell sources for knee cartilage tissue engineering

Jaramillo-Ferrada P

Adipose-derived stem cells form functional myotubes from mechanically-

induced differentiation whereas bone marrow-derived stem cells do not

Engler A

Hematopoietic Cell Therapy ► Hall 4

Chairs: Fricke S, Horwitz EM

Homologous and nonhomologous hematopoietic cell therapy: Tales of blood

and bone

* Keynote: Horwitz EM

Regeneration of hematopoiesis by non adherent bone marrow cells (NABMC)

after hematopoietic stem cell transplantation in humanized mice

Hilger N

Specific gene transfer to CD133-positive hematopoietic stem cells

Kneissl S

Substrate elasticity controls hematopoietic stem cell adhesion and migration

Lee-Thedieck C


Manufacturing Cell Products ► Hall 5

Chairs: Martin I, Savkovic V

Challenges for the manufacturing and clinical use of 3D cellular grafts

* Keynote: Martin I

Advances in cellular therapy using the Sepax 2 processing platform

Egermann M, Biosafe S.A.

Synthesis and evaluation of a bispecific antibody construct for targeting

and retention of bone marrow derived multipotent stromal cells in infarcted

myocardium

Gundlach IV CW

Cell culture media: Part of your therapeutic assay, part of your registration

Wiesner A, PAA Laboratories


02:00–03:30 pm

Induced Pluripotent Stem Cells ► Hall 2

Chair: Stolzing A

Transposon-mediated reprogramming provides a powerful tool for

understanding stem cell induction

* Keynote: Nagy A

Fibroblast contribution to bioartificial cardiac tissue formation from murine

induced pluripotent stem cells

Gruh I

Treating experimental spinal cord injury with human fetal neural stem cells or

human induced pluripotent stem cell-derived neural precursors

Romanyuk N


Program


Induced pluripotent cell-derived neural precursors in the treatment of focal

brain ischaemia in rats

Turnovcova K

Generation of equine induced pluripotent stem cells

Breton A

Nerve & Spinal Cord Regeneration ► Hall 3

Chair: Boltze J

Neural stem and progenitor cells in human cortical development and therapeutics

* Keynote: Kriegstein A

Autologous mesenchymal stem cell therapy for spinal cord injury: Effect of the

level of injury on long term safety and clinical efficacy

Gabr H

A unifying hypothesis of how MultiStem® provide therapeutic benefit in

multiple models of CNS injury and disease

Mays R, Athersys Inc.

Electrospun silk fibers promote oriented axon regeneration of CNS neurons in

vitro

Claudepierre T

Injectable hydrogel-based formulations for spinal cord regeneration

des Rieux A

Regulatory, Legal & Ethical Issues II ► Hall 4

Chair: Faltus T

The mandate to deliver cures: The law and politics relating to stem cell research

and its translation to the clinic

* Keynote: Siegel B

Regulatory complexities in the clinical translation of stem cells: The experience

of the Andalusian Initiative for Advanced Therapies

Cuende N


Application of risk management and requirements for processing practices for

medical products containing viable human cells – A new international standard

Kloth S

What are the “real“ ethical questions in regenerative medicine?

Sethe S

Cell Tracking & Imaging ► Hall 5

Chair: Tarnok A

Cell tracking and regenerative medicine: Clinical needs and technological

solutions

* Keynote: Bulte J

In vivo tracking of implanted bone marrow-derived mesenchymal stem cells

labelled by CM-DiI

* Keynote: Kasashima Y

In vivo tracking of intra-articularly injected SPIO-labelled MSC in a large animal

model of osteoarthritis using magnetic resonance imaging

Delling U



Program


04:00–05:30 pm

Embryonic Stem Cells ► Hall 2

Chairs: Hescheler J, Schröder I

From basic research to the clinic: Obstacles and options for stem cell therapies

in regenerative medicine with emphasis on pluripotent stem cells

* Keynote: Hescheler J

The potential of embryonic stem cells for clinical use in the horse

* Keynote: Guest D

Nanotopography-induced osteogenic differentiation of human embryonic stem

cells and adult skeletal stem cells

Kingham E

Functionality of human embryonic stem cell-derived neuronal cells in 3D

Ylä-Outinen L

Induction of osteogenic differentiation of murine embryonic stem cells by

confined compressive load and the role of RGD dependent integrins in

mechanotransduction

Hazenbiller O

Bone & Cartilage Engineering III ► Hall 3

Chair: Marquass B

Reduced chondrogenic hypertrophy in vitro following Sox9 gene transfer in

human mesenchymal stem cells

Kunz M

Proliferation potential of the MSCA-1+ subpopulation isolated from

jaw-periosteum

Olbrich M


Direct gene transfer for cartilage repair using coagulated bone marrow aspirate

– Bone morphogenetic protein-2 [BMP2] as potent chondrogenic inductor with

the risk of osteophyte formation in a rabbit model

Sieker J

Gene expression profiling of naturally occurring early intervertebral disc (IVD)

degeneration in dogs

Tryfonidou M

Viability and osteogenic response of pre-osteoblastic cells on poly(N-isopropyl-

acrylamide) functionalized with bone morphogenetic protein-2 (BMP-2)

Chatzinikolaidou M

Commercialization Strategies II ► Hall 4

Chair: Faber S

Regenerative medicine & the biopharmaceutical industry: Partnering & funding

mechanisms

* Keynote: Allsopp T

The cell therapy industry: Past, present & future

* Keynote: Mason C


Program


IVRMS II ► Hall 5

Chairs: Brehm W, Smith R

organized by the International Veterinary Regenerative Medicine Society

Effects of stem cell treatment in naturally-occurring tendon and ligament

injuries in horses

* Keynote: Smith R

In vivo tracking of TC-HMPAO labeled mesenchymal stem cells in

experimentally-induced tendon lesions in the equine distal limb

* Keynote: Vidal M

Regenerative approaches to equine tendonitis – Stem cell hierarchy through

disease modelling

* Keynote: Nixon AJ

Biochemical characteristics of the equine autologous conditioned plasma

Ionita JC

06:30 pm

Social Evening: Tropical Experience World Gondwanaland ► Zoo Leipzig


sPeCial: veterinary mediCine Program

In connection with the 2nd International Conference of the IVRMS and the World

Conference on Regenerative Medicine (Leipzig, November 2–4, 2011) the first IVRMS

workshop for veterinary practitioners and clinicians will be offered:

regenerative mediCine in veterinary CliniCal PraCtiCe

LectureS

\\ Blunn G

The interface between regeneration, reconstruction and replacement for

bone and joints

November 2, 2011, 04:00–05:30 pm, Hall 3

\\ Goodship A

Veterinary regenerative medicine – Past, present and future clinical

applications

November 2, 2011, 11:00 am–12:30 pm, Hall 5

\\ Guest D

The potential of embryonic stem cells for clinical use in the horse

November 4, 2011, 04:00–05:30 pm, Hall 2

\\ Ionita JC

Biochemical characteristics of the equine autologous conditioned plasma

November 4, 2011, 04:00–05:30 pm, Hall 5

SPeciAL: veterinAry meDicine


Program

\\ Kasashima Y

In vivo tracking of implanted bone marrow-derived mesenchymal stem cells

labelled by CM-DiI

November 4, 2011, 02:00–03:30 pm, Hall 5

\\ Koch T

Immune modulatory properties of equine umbilical cord blood, bone

marrow and adipose tissue-derived MSCs in vitro

November 2, 2011, 02:00–03:30 pm, Hall 3

\\ Nixon AJ

Regenerative approaches to equine tendonitis – Stem cell hierarchy through

disease modelling

November 4, 2011, 04:00–05:30 pm, Hall 5

\\ Nobert K

Regulatory affairs for stem cell use in veterinary medicine


\\ Rankin S

Endogenous release of stem cells


\\ Smith R

Effects of stem cell treatment in naturally-occurring tendon and ligament

injuries in horses

November 4, 2011, 04:00–05:30 pm, Hall 5

\\ van Weeren R

The potential of (hybrid) scaffolds for the treatment of orthopaedic disease


\\ Vidal M

In vivo tracking of TC-HMPAO labeled mesenchymal stem cells in

experimentally-induced tendon lesions in the equine distal limb

November 4, 2011, 04:00–05:30 pm, Hall 5


Anzeige

Fraunhofer Life Science Symposium 2012

stem cells and clinical applications

November 29–3

0, 2

012

7th annual congress of the german society for stem cell research

associated with

fraunhofer life science symposium 2012

www.fs-leipzig.com

frAunhofer Life Science SymPoSium


Program

fraunhofer life sCienCe symPosium

orgAnizAtion

SeSSionS

\\ Surfaces & Cell-Material Interaction

Thursday, November 3, 2011, 11:00 am–12:30 pm, Hall 3

\\ Biomaterials & Scaffolds

Thursday, November 3, 2011, 02:00–03:30 pm, Hall 3

\\ Biomedical Materials & Implants

Thursday, November 3, 2011, 04:00–05:30 pm, Hall 3

Biomaterials and Scaffolds

2011

FraunhoferLife Science SymposiumLeipzig


frAunhofer Life Science SymPoSium


Program

Select Biosciences Business Tutorial: Stem Cells Worldwide Market Analysis

In Conjunction with the World Conference on Regenerative Medicine (WRM) 2011

17:00-20:00, 3 November 2011, Leipzig, GermanyPresented by Enal Razvi, PhD, Biotechnology Analyst, Select Biosciences Ltd

Scope of this Business TutorialAdult Stem Cells, Cord Blood Stem Cells, hESCs/iPSCs, and Cellular Therapy: Technology Trends,

Market Analysis, and Pipeline of Therapeutics in Development

Topics Presented at this Tutorial

• Primary Market Survey Data from Global Respondent Pools • Types of Adult Stem Cells being Studied Currently in Disease Areas • Current Status of Clinical Trials Utilizing Adult Stem Cells: Breakout by Disease Area, Trial Metrics • Current Status of Approved Cellular Therapeutics • Quantitative Research Trends and Quantitative Market Metrics/Penetrance: Types of Reagents, Culture Media/Supplements, and Vendors Supplying these Research Products • Umbilical Cord Blood Banking Market Analysis: Size, Growth Rate, Market Segmentation, Global Distribution, Public vs. Private Cord Blood Banking • Market Analysis of Current Research Trends in hESCs and iPSCs

Who Should Attend

• Scientists in Academia, Biotechnology and Pharmaceutical and Companies • Business Development, Licensing, and Marketing Executives in Pharmaceutical and Biotechnology companies • Representatives from Academic Institutions (Licensing and Technology Transfer) • Established and Start-up Companies Currently in or Contemplating Entry into the Stem Cells Marketplace • The Investment Community

Registration and more information at the registration desk.

Total Price: €795



Poster Presentation

\\ overview Poster exhibition

fLoor 0

PoSter cAtegorieS

■ Stem Cells

■ Cell- & Tissue Engineering

■ Cell Therapy

■ Models

■ Molecular Mechanisms & Biomarker

■ Immunological Aspects

■ Biomaterials & Scaffolds

■ Regulatory

escalators

lift

stairs

001–008 165–172

173–204245–276205–244

009–062

111–164

063–086 087–110


Posters

■ PP001 Phenotypic characterisation of lin-CD45- VSEL cells in hUCBAlt R

■ PP002 Recent findings on the effects of adult stem cells in the treatment of heart failure patients (A clinical studies review)Arti A

■ PP003 Recent findings on the effects of adult stem cells in the treatment of cardiomyopathy patients (A clinical studies review) Arti A

■ PP004 New findings on the application of adult stem cells in the treatment of cardiomyo-pathy (A preclinical studies review)Arti A

■ PP005 New findings on the application of adult stem cells in the treatment of heart failure (A preclinical studies review)Arti A

■ PP006 Epithelial differentiation potential of adipose-derived stem cellsBaer P

■ PP008 Colonization of collagen scaffolds by adipocytes derived from mesenchymal stem cells of the common marmoset monkeyMueller T

■ PP009 Establishing selection criteria for enrichment, preservation and recovery of optimum quantity of hematopoietic stem cells from umbilical cord blood: A study to improve efficiency in cord blood stem cell bankingBiswas A

■ PP010 Characterization of osteoprogenitors functionally isolated from human mesenchymal stem cells by a runx2 reporter adenovirus Bruderer M

■ PP011 Stem cell self-renewal: Lessons from benign tumorsBullerdiek J

■ PP012 Quantitative x-ray microanalytical evaluation of endothelial and endothelial-like cells for vascular tissue engineeringCampos A

■ PP013 Isolation, maintenance and characterization of multipotent mesenchymal stem cells from canine umbilical cord matrixCha SH

■ PP014 Growth features and cellular crosstalk in human gliomaChoschzick I

■ PP015 Production of GABAergic neurons differentiated from BMSCs-derived -neurosphere cellsDarabi S

■ PP017 Regeneration of the intervertebral disc (nucleus pulposus) using in vitro differen-tiated human mesenchymal stem cellsEhlicke F

■ PP018 Human tissue-culture adapted hepatocytes for cell therapy, drug testing and cancer researchFekete N

■ PP019 Hypoxia induces embryonic stem cell-specific micro RNA cluster 302 and pluripotency-associated genes in human mesenchymal stroma cellsFoja S


Poster Presentation

■ PP020 Comparision of cell populations from salivary glands obtained by different preparaton proceduresFrahm S

■ PP022 Characterization of neural differentiation of embryonic stem cells by marker expression analysisFronz U

■ PP023 Efficiency of adipogenic differentiation methods in mesenchymal stromal cells from diverse sourcesGittel C

■ PP024 Isolation of mesenchymal stromal cells from solid tissues: Cell features after digestion versus migrationGittel C

■ PP025 Expression pattern of stem cell specific markers and micro RNAs during rabbit embryonic development and in embryonic stem cellsGocza E

■ PP026 A new method to culture neural stem cells of the myenteric plexus from adult mouse by maintaining the stem cell niche in vitro Grundmann D

■ PP027 The effects of hypoxia on cultured human corneal epithelial stem cellsHenein C

■ PP028 The human appendix, a potential neural stem cell sourceHeumüller S

■ PP029 Comparison of human embryonic SA002 stem cell culture techniques concerning to their differentiation potential in vitro and in vivoKeil M

■ PP030 Generation of hematopoietic lineage cells from human adeno-iPS cells Khamisipour G

■ PP031 Multipotent stromal cells derived from human embryonic stem cells exhibit functional characteristics of perivascular progenitor cellsKim JM

■ PP032 Dynamics of neuronal development in the adult hippocampusKirste I

■ PP033 TGF-ß and bovine serum albumin are major factors influencing human embryonic stem cell proliferation Knöspel F

■ PP034 Neural differentiation of adipose-derived mesenchymal stem cells on IKVAV-modified superporous hydrogel scaffoldsKubinova S

■ PP035 Cultivation of cells with stem potential from nail matrixKyryk V

■ PP036 Human embryonic stem cells as a model system and a source of cells for regenerative medicineLagarkova M

■ PP037 GMP-conform expansion of umbilical cord derived mesenchymal stem cellsLavrentieva A

■ PP038 Effect of human embryonic stem cell-derived neuronal precursor cell transplantation into the cerebral infarct model of rat with exerciseLee SU

■ PP039 A novel cardioprotective mechanism mediated by bone marrow c-kit+ERalpha+ cell via paracrine IL-6Li J


■ PP041 Low serum culture conditions for the expansion of human mesenchymal stromal cells eliminates the need for serum testingMontzka K

■ PP042 Different responses to DNA damage and repair in ADSC in presence of UV light and H2O2Naaldijk Y

■ PP043 Amniotic fluid as a novel and rich source of stem cells for regenerative medicineOlkowska J

■ PP044 Hepatic differentiation of human mesenchymal stromal cells by lentiviral expression of transcription factorsPacher M

■ PP045 Activation of skeletal myogenic differentiation in adipose-derived stem cells by uniaxial cyclic strainPennisi CP

■ PP046 A serum free strategy correlating Stat3 activity to neurogenic potential of human umbilical cord-derived mesenchymal stem cells brings brain related regenerative medicine closerPerruisseau-Carrier C

■ PP047 Development of optimal cryopreservation protocol for suspensions of mesenchymal stem cells with application of systematic parameter optimizationPogozhykh D

■ PP048 How mesenchymal stem cells modulate the cytokines expression in the tissue engineered bladder wallPokrywczynska M

■ PP049 Integration of stem cell populations into biomaterials and their application for skin tissue regenerationRamanauskaite G

■ PP050 Clonal expansion and features of brain tumor stem cellsRoth S

■ PP051 An adjuvant anti-tumour therapy by inhibition of Hsp27 in breast cancer stem cellsRuschpler P

■ PP052 Understanding the molecular nature of resident cardiac progenitor cells using omics-based approachSamal R

■ PP053 Hair follicle melanocytes – Obtaining, differentiating, selecting, upscalinKirsten M

■ PP054 Reprogramming of bone marrow stem cells into endothelial-like cells by application of endothelial growth factorSchlegel F

■ PP055 Differentiation of murine embryonic stem cells (MESC) into hepatocyte-like cells for in vivo applicationSiegert A

■ PP056 Detection of murine embryonic stem cells after transplantation in NOD/SCID mice by in vivo imaging (bioluminescence)Stecklum M

■ PP057 Housekeeping gene stability in human bone marrow-derived mesenchymal stromal cells during adipo- / chondro- and osteogenesisStuder D

■ PP058 Bone marrow targeted liposomal drug delivery systemsTezcaner A

■ PP059 Potential of Ti surfaces to select osteogenic stem cells for repair and regenerationTillotson M


Poster Presentation

■ PP060 Cardiac migration of endogenous mesenchymal stromal cells in patients with inflammatory cardiomyopathyVan Linthout S

■ PP061 Induced pluripotent stem cells of the common marmoset monkey display high cellular plasticityWiedemann A

■ PP062 Chemical modification of the epigenetic pattern imrpoved the differentiation poten-tial into hepatocyte-like and osteoblast-like cells of human ad-MSCs from old donorsYan X

■ PP064 Augmentation of urinary bladder wall with amniotic membrane seeded with mesen-chymal stem cells, regeneration of smooth muscle layer does not restore proper bladder function – Rat model research studyAdamowicz J

■ PP065 Development of a heterotypical cornea substitute using transdifferenciated umbilical cord stem cellsAlaminos M

■ PP066 Biocompatibility of laser microstrured 3D polymeric scaffoldsBaltriukiene D

■ PP067 Physical and numerical design of a fluidised bed bioreactor for stem cell expansionBenzeval I

■ PP068 In vitro modelling of squamous cell carcinoma invasionBerning M

■ PP069 Towards the reconstruction of the subcutaneous fat layerWerner K

■ PP070 Combination of long-term stable fibrin gels and porous scaffolds for engineering of volume-stable adipose tissueWittmann K

■ PP071 Cultivation of human parotid cells on a decellularized porcine jejunal segment and on a polyurethane foamBurghartz M

■ PP072 Injectable tissue engineered pulmonary heart valve implantation in a pig model Dohmen P

■ PP073 Angiogenetic factors modulate the tissue engineering of vascularized adipose tissue for an autologous soft tissue replacementDolderer JH

■ PP074 The lipid composition of liver changes significantly in dependence on nutrition – An MS and NMR studyEibisch M

■ PP075 Collagen-heparin layer-by-layer nanocoatings incorporating nanoparticles for drug releaseFerreira Duarte AM

■ PP076 PLGA-based scaffolds containing sol-gel bioactive glass enhance in vitro osteogenesis of human mesenchymal stem cellsFilipowska J

■ PP077 Micromorphological investigations of intervertebral disc degeneration using electron microscopyFriedmann A

■ PP079 Increased angiogenesis elicited by boron-containing bioactive glassGorustovich A

■ PP080 The development of a vascularized skin modelGroeber F

■ PP081 Botanical scaffold in salvage for human tissue regenerationGuhatakurta S


■ PP082 Injection of mesenchymal stem cells after repair of a degenerated rotator cuff – An experimental study in rabbitsHaddad-Weber M

■ PP083 Photopolymerizable biopolymer-based hydrogels for the generation of artificial cartilage Hoch E

■ PP084 Biomechanical analysis of in-vivo performance of a novel hydroxyapatite-based bone void filler under low-amplitude and high-frequency vibrational conditionHooshiar Ahmedi SA

■ PP085 Vascularized heart tissue model to study heart diseasesIkonen L

■ PP086 Policaprolactone-based matrices as a potentially scaffolds for urinary tract regenera-tionKloskowski T

■ PP087 Blue light collagen cross linking to treat progressive myopiaKörber N

■ PP088 Cultivation and osteogenic differentiation of murine bone marrow multipotent stromal cells in micromass cultureKuchuk O

■ PP089 Development of an animal model for tissue-engineered laryngo-tracheal replace-mentsLange P

■ PP090 Usage of FGF-18 on bone marrow mesenchymal stem cell for bone regenerationLee S

■ PP091 Chondrogenic differentiation potential of human cartilage cells in pellet cultures after stimulating with TGF-ß1 and IGF-1Lochner K

■ PP093 Bone tissue engineering by porous composite carbonated hydroxyapatite/tricalcium phosphate (CHA/TCP) ceramic scaffolds and autological multipotent mesenchymal stromal cells (auto-MMSC) for repair rabbit‘s segmental diaphyseal defect Mamonov V

■ PP094 Development of a perfusion bioreactor system for the cultivation of large-scaled cell-seeded scaffoldsMilan F

■ PP095 Auricular reconstruction using a novel nanocomposite 3D scaffold and cellular engineeringNayyer L

■ PP096 Driving malignancy in human cancer cell lines on a three-dimensional (3D) collagen matrix – A basis for the development of human in-vitro tumor modelsNietzer SL

■ PP097 Development of autologos full skin transplantatMöller Y

■ PP098 Effect of uniaxial cyclic strain on the assembly and differentiation of mammalian myogenic precursorsPennisi CP

■ PP099 Development of extracellular matrix in scaffold free cartilage transplantates from in vitro to in vivo in the sheep modelPonomarev I

■ PP100 Non-invasive characterization of cartilage extracellular matrix by raman micro-spectroscopyPudlas M

■ PP101 Three-dimensional cultivation of single-cell-derived hTERT-expressing human mesen-chymal stromal cells on cancellous bone allograftRauh J


Poster Presentation

■ PP102 Mineralized human primary osteoblast matrices as a model system to analyse inter-actions of prostate cancer cells with the bone microenvironmentReichert J

■ PP103 Human artificial blood vessel tissues as a pathogenesis model in vascular biomedical researchRennert K

■ PP104 Rheological characterization of criopreserved tissue-engineered human oral mucosaAlaminos M

■ PP105 The biostent – Novel concept of a viable stent structureRongen L

■ PP106 Tissue engineering for breast reconstruction: A review of current trendsSadr AH

■ PP107 Target-in: Specific gene delivery to cell types of choiceSchneider IC

■ PP108 Epidermal stem cells in cutaneous wound healingScholz P

■ PP109 Ultrastructure of cerebral intranidal arteriovenous malformation aneurysmGöhre F

■ PP110 Mechanical characterisation of a chitosan – Hyaluronic acid injectable scaffold material for spinal disc repairSchwan S

■ PP111 Comparison of equine mesenchymal stromal cells derived from different sourcesBurk J

■ PP112 Customised decellularized vascular scaffoldsSheridan W

■ PP113 Modification of porous polymer scaffolds with collagen for cells cultivationShved Y

■ PP114 Biodegradable polyurethanes for myocardial tissue regenerationSilvestri A

■ PP115 Precise microanalysis of cell cultivation media by using an amperometric biosensor system with on line microdialysisSpohn U

■ PP117 Chondrogenesis of scaffold-free bone marrow-derived human mesenchymal stem cells through cyclic, uniaxial, unconfined compressive loadingTing SYW

■ PP118 Artifical extracellular matrix composed of collagen I and sulphated glycosamino-glycans induces a proliferative dermal fibroblast phenotype in vitrovan der Smissen A

■ PP119 Development of a tissue-engineered vascularized bone implantVater C

■ PP120 Adherent cells grow at different rates on spherical microcarriers of different sizeVoigt M

■ PP121 The influence of the cell source on the sufficiency of tissue engineered heart valveWeber M

■ PP122 Biofunctionalized microfibres help to form three-dimensional (3D) capillary-like structures in a fibrin gelWeinandy S

■ PP123 Establishment of an in vitro model with human mesenchymal stem cells and micro-vascular endothelial cells onto an electrospun collagen type I/II scaffold for meniscal repairWeymüller J

■ PP124 Property for hard tissue formation in sponge scaffolds by bone marrow cells with alginate in vitroYoshikawa M


■ PP125 Automated isolation of semi-adherent macrophages from a fibroblast-contaminated culture using the multifunctional, robotic cell separation system CellCelectorTM

Zoldan K■ PP126 Establishment of a femoral bone defect model for immunodeficient mice

Niederlohmann E■ PP127 Different therapeutic treatment trials to improve re-endothelialization in order to

avoid re-stenosisvon der Ruhr J

■ PP128 A novel autologous stem cell procedure for the treatment of aplastic anaemia using reprogrammed mature adult cells: A pilot clinical studyAbuljadayel I

■ PP129 Photoreceptor precursor cell transplantation: The outer segment in focusEberle D

■ PP130 Angiogenic properties of human adipose-derived mesenchymal stem cells decline with donor age due to the impairment of pro-angiogenic factors secretionEfimenko A

■ PP131 Development of a human extracellular matrix for applications related with stem cells and tissue engineeringEscobedo-Lucea C

■ PP132 Pilot trial of recombinant human growth hormone for remyelination in multiple sclerosis: Current status and preliminary safety analysisEttrich B

■ PP133 GMP quality control platform for stem cell clinical grade production in cell factoriesFerrandi C

■ PP134 Autologous fibroblast culture in the treatment of chronic venous leg ulcers using a new delivery techniqueGabr H

■ PP136 Generation of cells without mitochondrial DNA (ρ0 cells): Analysis of mtDNA deple-tion in 143B.TK- cellsHeller S

■ PP137 Functional properties of human mesenchymal stem cells (hMSC) derived from multiple sclerosis patients as compared to those of healthy donorsKassis I

■ PP138 Prolonged clinical effects of mesenchymal stromal cell therapy in patients with chronic coronary artery disease – 24 months follow-upKastrup J

■ PP139 Blood derived stem cells: Therapeutic applications in the ophthalmology fieldMarfè G

■ PP140 10-year experience in autologous disc chondrocyte transplantation (ADCT): A critical clinical review of 115 casesMeisel HJ

■ PP141 Bone marrow mononuclear cells effect on dermal fibroblast proliferationMenéndez Menéndez Y

■ PP142 Antigen specific CD8 T cell transmigration into tumoursOelkrug C

■ PP143 Survival and functional restoration of human fetal ventral mesencephalon following transplantation in a rat model of Parkinson’s diseaseMoellers S

■ PP144 Expanded adipose derived stem cells for veterinary medicine applicationsSmirnova N

■ PP145 MCAM/CD146 expression on human mesenchymal stromal cells influences prolifera-tion and maintenance of hematopoietic stem and progenitor cells during co-cultureStopp S


Poster Presentation

■ PP146 A new specially formulated defined xeno-free tissue culture medium for growth and expansion of human AT-MSCsTallone T

■ PP147 Human cardiac biopsy-derived cells reduce Coxsackievirus B3-induced myocarditis and require interferon-gamma for their activationVan Linthout S

■ PP148 Formation features of ischemic necrosis and myocardium cryonecrosisBabaieva G

■ PP149 Visualization of DMSO diffusion in engineered constructs for long term-storageBernemann I

■ PP150 Normothermic acellular ex vivo liver perfusion (NEVLP): Development of a new method for preservation, assessment and repair of marginal organs – shown in a pig model with livers donated after cardiac death (DCD)Boehnert MU

■ PP151 A new short time rat model of mucosal inflammationBreitrueck A

■ PP152 “Hypoxic protocol“ for MMSC ex vivo expansion to meet needs of regenerative medicineBuravkova L

■ PP153 Murine and human postnatal ENS progenitor cells integrate into murine bowel in vivoDettmann H

■ PP154 New heterocyclic compounds for regeneration of mammalian cochlear sensory cellsWank U

■ PP155 Fetal liver regeneration in ratsElchaninov A

■ PP156 Bone marrow-derived stem cell transplantation in a mouse model of retinal degene-rationEnzmann V

■ PP157 Bone marrow derived multipotent stromal cells promote myocardial fibrosisFatkhudinov T

■ PP158 Synthetic vesicles: Photo cross-linked and pH sensitive polymersomes as bionanore-actorsGaitzsch J

■ PP159 Effect of topical nitric oxide donor (0.2 % glyceryl trinitrate) on wound healing in diabetic wistar ratsGhori V

■ PP160 Development of a large animal model for intervertebral fusion in lumbar spinal motion segementsHohaus C

■ PP162 Nonlinear finite element model of the spine and investigating the role of muscle under compression loadKhaksar FM

■ PP163 Bone regenerates via dedifferentiation of osteoblasts in the zebrafish finWeidinger G

■ PP164 Establishment of a large animal model for implantation of decellularized esophagus scaffolds: A pilot studyKoch H

■ PP165 Macrophage infiltration is inhibited by genipin cross-linking of decellularized esophagus scaffoldsKoch H

■ PP166 Angiogenesis followed by transplantation of autologous and allogeneic cellsMakarov A


■ PP167 Service offer: Flow & image cytometry and in vivo imagingMittag A

■ PP168 Effects of exposure time on the luminescence properties of biologically formed apatite in simulated body fluidMozafari M

■ PP169 Evaluation of intra-osseous defects regeneration treated by platelet rich plasma using silver-stained nucleolar organizer regions (agnors)Nassan M

■ PP170 Synovial membrane derived mesenchymal stem cells in hyaluronic acid scaffold transplantation for regeneration of cartilage defectsBekbolsynov D

■ PP171 Immune cells-targeted delivery of mannan-coated superparamagnetic iron oxide nanoparticles for detection of micro-metastasisPark IK

■ PP172 The role of the integrator complex during planarian regenerationReuter H

■ PP174 TGF-beta superfamily member activin A improves survival of spiral ganglion cells in vitroWarnecke A

■ PP175 In vitro evaluation of promising key factors for regenerative stroke treatment approachesWielsch B

■ PP176 Impaired endothelial regeneration after human parvovirus B19 infection of circulat-ing progenitor cells with endothelial regenerative potential (CERP)Zobel T

■ PP177 The use of zinc finger in molecular diagnosticsAllelein S

■ PP178 CXCR4 expression in human mesenchymal stem cells enhances in vitro migrationAndersen RK

■ PP180 An agent-based framework to simulate cell-cell communication of adult stem cell populations in vitroBecker T

■ PP181 A screen for ion channels and transcription factors involved in zebrafish heart regenerationChan WH

■ PP182 Non-invasive and non-destructive in situ monitoring of endothelial cells cultured in fibrin gels under perfusion bioreactor conditions by positron emission tomography imagingChouinard JA

■ PP183 The protein and lipid composition of coronary atherosclerotic plaque and its structural analysisFaghihi S

■ PP184 Regenerating myeloperoxidase activity contributes to cellular termination of inflammationFlemmig J

■ PP185 A novel molecular method for earliest diagnosing cancersHan-You X

■ PP186 The new carcinogenesis theory of gene multiple hitsHan-You X

■ PP187 Authentication of cells in therapy research applying cytogenetics and genome wide high resolution single-nucleotide polymorphism arrayHolland H


Poster Presentation

■ PP189 Towards a genetic screening test for dyslexia allowing functional regeneration: Steps towards identification and analysis of genetic risk factorsKirsten H

■ PP190 Effect of aging and estradiol on membrane linked functions in female rat brainKumar P

■ PP191 Biodegradable microcarriers as cell delivery vehicle for in vivo transplantation and magnetic resonance monitoringLovati AB

■ PP193 Chemopreventive activities of Curcumin and Diclofenac in early colon carcinogenesis: Molecular mechanisms involved and down-regulation of COX-2 and iNOS through suppression of NF-kappaB activationRana C

■ PP194 Determination of peptide composition of animals‘ heart extractsRogoza L

■ PP195 Metabolic and gene expression profile of MMSCs under low oxigenRylova J

■ PP196 Magnetic bead-based lab-on-a-chip system for the point-of-care diagnosticsSandetskaya N

■ PP197 Planarian Smed-POU5, a POU transcription factor of subclass V, maintains the stem cell identity and self-renewal ability of adult stem cells in Schmidtea mediterraneaSchmitz H

■ PP198 The analysis of native and oxidatively-modified phospholipids and blood lipoproteins by MALDI-TOF mass spectrometryTeuber K

■ PP199 Human parvovirus B19 (B19V) infection of circulating cells with endothelial regene-rative potential induces apoptosis via a caspase-8/-10 dependent mechanismZobel T

■ PP200 Anti-inflammatory effects of bovine colostrum on the intestinal epitheliumBodammer P

■ PP201 Immunomodulatory effects of benzo(a)pyrene influencing the outcome of infection with salmonella entericaFueldner C

■ PP202 Transforming growth factor b mRNA expression in early stage and metastatic endo-metrial cancer microenvironment versus normal endometriumGiannice R

■ PP203 Reciprocal interaction effects on MMSCs and PBMCs proliferation and viabilityGornostaeva A

■ PP204 Acetylsalicylic acid stabilizes immune functions of macrophagesKnauer J

■ PP205 Role of the danger signal molecules S100A8 and S100A9 in the antiviral response of epithelial cellsKerkhoff C

■ PP206 Modelling hematological parameters after irradiationOelkrug C

■ PP207 An indispensable role of CD2 in initiating T cell proliferation in the patients suffering from visceral leishmaniasisSinha S

■ PP208 The role of mast cells and Weibel-Palade-bodies in mesenteric infarctionSommer HJ

■ PP209 Approaches to T regulatory cell therapy in autoimmunity and GVHDTheil A

■ PP210 Investigation of corrosion of WE43 MG-alloy for biodegradable implants applicationsAscencio M


■ PP211 Effect of extracellular matrix on proliferation and adhesion properties of bone marrow mesenchymal stem cells and hair follicule stem cells: Utility for tissue and organ regenerationBajek A

■ PP212 Characterization of agarose gels in an ElectroForce® test systemBöhm R

■ PP213 PLGA dynamic degradation and mechanical propertiesBöhm R

■ PP214 Multifunctionalized nanoporous silica nanoparticles for tissue engineering applicationsChristel A

■ PP215 Application of upcyte® hepatocytes on 3D cell cultureDähn C

■ PP216 A comparative PM-IRRAS and ellipsometry study of the interaction of bovine serum albumin with a gold surfaceDargahi M

■ PP217 Phosphorylation of polymers and their electrospinning- towards development of biomimetic osteoconductive and osteoinductive matrices for bone regenerationDatta P

■ PP218 A new biodegradable collagen cell carrier for tissue engineering of matrix-stabilized urotheliumVaegler M

■ PP219 Lockyballs: Bottom-up approach for rapid in vivo 3D tissue biofabricationDavid Alencar de Sena Pereira F

■ PP220 Does platelet-derived-growth-factor-AB in autologous platelet-rich plasma gels influence the tissue development of human umbilical cord artery smooth muscle cells?Dietrich M

■ PP221 Influence of a calcium carbonate scaffold on human mesenchymal stem cells prolifera-tion and differentiationDivieto C

■ PP222 Regeneration of decellularized equine pericardial patches implanted into the systemic circulationDohmen P

■ PP223 An experimental study of stentless decellularized xenografts implanted into the aortic position of the juvenile sheepDohmen P

■ PP224 Functional validation of decellularized extracellular matrix preparations derived from mesenchymal stromal cells overexpressing jagged-1Duryagina R

■ PP225 Nanostructuring of titanium by high presure torsion influences mesencymal stem cell response and bacterial adhesionFaghihi S

■ PP226 Biological evaluation of a novel nanocomposite of hydroxyapatite/layered double hydroxides/gelatinFayyazbakhsh F

■ PP228 Composite hydrogel scaffold for nerve tissue engineeringBorgio L

■ PP229 Fabrication of scaffold matrix from goat lung tissue and its biocompatibility study using Hep G2 cell line for tissue engineering applicationGupta S

■ PP230 Characterization of iridium / titanium oxide coatings for biomedical applicationsHabibzadeh S


Poster Presentation

■ PP231 Interaction of Ni(II)-NTA-modified poly(ethylene imine)-maltose with HIV-derived GP160 capturing in dendritic cellsHauptmann N

■ PP232 Gold nanoparticle mediated cell manipulation using ultrashort laser pulses for cell perforation and transfectionHeinemann D

■ PP233 Synthesization and characterization of magnetic nanoparticles via inert gas conden-sationHennes M

■ PP234 Functionalization of 3D porous bone substitutes using layer-by-layer technologyJacobi A

■ PP235 Biomimetic control of cell behaviour by substrate independent modification with “Click&Seed“ systemJaroš J

■ PP236 Impact of sulfated glycosaminoglycans on monocyte to macrophage differentiationKajahn J

■ PP237 Osteogenesis by bone marrow cells in novel hybrid alginate/calcium phosphate sponge scaffoldKakigi H

■ PP238 Influence of pore geometry and growth factor (BMP-2) application on in-vitro tissue formation in hydroxyapatite scaffoldsKommareddy KP

■ PP239 In vitro modulation of human corneal endothelial cell behaviors using topographical and biochemical cuesKoo S

■ PP240 Martensitic transformation and magnetic properties of freestanding single crystalline Fe70Pd30 thin filmsMa Y

■ PP241 Nanoparticles for controlled release of therapeutic molecules after strokeI. Santos M

■ PP242 The interaction between mouse mesenchymal stem cells and poly (3-hydroxy butyrate) nanofibrous scaffolds for tissue engineering applicationsMasaeli E

■ PP243 Neuronal protection by nanoparticle mediated rolipram applicationScheper V

■ PP244 Combination of self-assembling peptides and scaffolds: Characterization, protein delivery and biological performanceMonleon-Pradas M

■ PP245 Heat-treatment effects on the formation of phase pure nanocrystalline Mg2SiO4 bioceramic intended for bone tissue engineeringMozafari M

■ PP246 Forsterite addition to bioactive glass as a novel hybrid nanocomposite to improve its mechanical and biological propertiesMozafari M

■ PP247 Chitosan/gelatin scaffolds with controlled mechanical properties engineered for soft tissue applicationsMozafari M

■ PP248 Nerve regeneration enhancement of polyvinyl alcohol nanofibrous scaffolds by adding chitosanMozafari M

■ PP249 Finite element analysis of a novel scaffold based on gelatin and bioactive glass as a substitution of femoral head tissueMozafari M


■ PP251 Chondroitin sulfate nanoparticles for delivery of growth factors in cornea regenera-tionPárraga M. JE

■ PP252 Restricted microdomains for time-lapsed neural precursor cells studies by laser assisted micropatterningPerez-Hernandez H

■ PP253 Influence of glycosmaminoglycan sulphation on the interaction with interleukin-8Pichert A

■ PP254 Design of a versatile surgical patch Prost N

■ PP255 Management of complex dermal wounds using a new collagen cell carrier (CCC): An in vivo evaluation of split skin graft transplantation combined with CCC in ratsHeld M

■ PP256 Evaluation of biocompatibility and biodegradation of a novel collagen cell carrier (CCC) for in vivo applicationHeld M

■ PP257 Tailor-made collagen-based matrices for cell culture, medicine and diagnosticsReinisch H

■ PP258 Next generation deep brain stimulating devices with neuropil-mimicking cell coverRichter A

■ PP259 Design of positively charged hydrogel systems for the in-situ immobilization of enzymes through fast cross-linkable monomers and macromonomersRichter A

■ PP260 New nonwoven-based scaffold structures for mesenchymal stem cellsRoß R

■ PP261 An innovative method to produce biodegadrable polymer scaffolds for tissue engineeringSantos L

■ PP262 Upcyte® microvascular endothelial cells are able to repopulate an acellularized scaffoldScheller K

■ PP263 Resorbable ceramics based on calcium pyrophosphate and alkali polyphosphatesShiryaev M

■ PP264 Generation of human corneal endothelial cell sheets using smart cell culture carriersTeichmann J

■ PP265 Encapsulation of adipose-derived stem cells in alginate membrane for regenerative medicineTosca MC

■ PP266 Silk fibroin film as adipose derived stem cell scaffolds for skin advanced therapyTosca MC

■ PP267 Adipose stem cells and pancreatic islets on fibroin non-woven scaffolds: Technological characterization and cultureTosca MC

■ PP268 To better define the surface density of vitronectin on TCPS for the long-term culture of pluripotent human embryonic stem cellsYap L

■ PP269 Analysis of the migration of the stromal cells of bone marrow and fibroblasts of rabbit in the collagen and fibrin gelsYudintceva N

■ PP270 Smart methylcellulose hydro-gel for engineered human cardiac progenitor cell (hCPCs) sheetsZamperone A


Poster Presentation

■ PP271 Collagen cell carrier for neural cell culturesZhang Y

■ PP272 The search for new stem cell research rules between the poles of the recent pre-implantation genetic diagnosis sentence of the federal supreme court and the impact of reprogrammed stem cells in GermanyFaltus T

■ PP273 Stemm cells & ethics: Negative propaganda in public discourse and the necessity of new ways to handle itReichardt JO

■ PP274 Overview of Japanese draft guidelines on ensuring quality and safety of products derived from engineered human stem cellsSato Y

■ PP275 Setting standards: European and international standardization landscape in the field of medical devices utilizing tissuesWenzelewski K

■ PP276 Towards a genetic screening test for dyslexia: A survey on acceptanceWilcke A


Vertrauen erfahren

The Beetles

Jetzt noch besser mit dem optionalen Fender®-Soundsystem.

Das Auto.

Ihr Volkswagen Partner

Volkswagen Automobile LeipzigMerseburger Straße 200 • Delitzscher Straße 190 • Richard-Lehmann-Straße 118Torgauer Straße 331 • Autohaus Muldental, Leipziger Straße 93, 04668 Grimma


evening funCtions

evening funCtions

oPening Ceremony (hall 1)

and get-together (exhibition

area)


Regenerate, Re-Energize, Reminisce and

Relax at the opening ceremony! Don’t

miss this chance to mingle and mix with cutting edge researchers from every corner of

the globe as well as the leaders of the companies who are involved in translating this

research into cell and tissue engineer ed products.

Be our guest at the opening ceremony (05:30 pm at Hall 1) and, thereafter, at the get-

together in the exhibition area (included in the registration fee; registration required).

Poster Party (Poster exhibi-

tion area floor 0)


In order to give each delegate adequate

opportunity for an intensive discussion

of the posters we invite you to join an

informal Poster Party with beer and

snacks (included in the registration fee;

registration required).

Poster authors are requested to be present at their posters.

Start: 05:30 pm at the Poster Exhibition Area Floor 0

Award ceremony for best abstract and best poster: 07:00 pm

Best Abstract and Best Poster Award kindly supported by Pluristem Therapeutics Inc.


With me At

gondwanalandDINNERHAVE

gondwanalandENJOY

With me At

gondwanalandRELAX

With uS At

gondwanalandCOMMUNICATE

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evening funCtions

troPiCal exPerienCe world

gondwanaland


Where dinosaurs wandered over the

landmass...

More than 17,000 different tropical plants,

around 300 exotic animals and the kind of

virgin rain forest which once characterised

the lost continent of Gondwana – all of

this comes alive in the unique Tropical

Experience World Gondwanaland at

Leipzig Zoo. Exciting tracks lead you

through the rainforest in a huge tropical

hall where animals from these three

continents will cross your path. Birds will

fly through the air and monkeys climb in

the trees...

Be our guest in this unique scenery and don‘t miss the chance to mingle with colleagues

and friends in the evening of November 4, 2011.

Tickets can be purchased at the registration desk.

Price: 70.00 € including VAT, guided tour of Gondwanaland, food and beverages

Meeting point: Entrance Gondwanaland (Tempelfoyer) at 06:30 pm


\\ exhibition Plan

LeveL +1

exhibitorS

Company Booth

Analytik Jena AG Jena (D) 22

ASKION GmbH Gera (D) 2

Auto Q Bioscience Ltd. Theale, Berkshire (UK) 39

BD Biosciences Erembodegem (BE) 37

Beckman Coulter GmbH Krefeld (D) 5

BioLegend GmbH Fell (D) 36a

Biometra GmbH Göttingen (D) 22

Biomomentum Inc. Laval, QC (CA) 32

BIO-NET LEIPZIG Technologietransfergesellschaft mbH Leipzig (D) 10

Biosafe S.A. Eysins (CH) 45

biosaxony e.V. Dresden (D) 11

biosaxony Management GmbH Dresden (D) 11

CaridianBCT, Inc. Lakewood, CO (USA) 28

Cell Cryogenics Ltd. Cambridge (UK) 35

Cell Guidance Systems Ltd Bar Hill, Cambridge (UK) 40

CellGenix GmbH Freiburg (D) 36

Cenibra GmbH Bramsche (D) 26a

hall 1

hall 2 hall 3

hall 4 hall 5

escalators

lift

stairs

36a 30a 26a27a31a

3839

3637

3435

3233

3031

2829

4041

4746

42 43 44 45

2627

25 24 23 22 21 20 19 17 16 15 14 13 12 6 5 4 3 2 111 10 9 8 718

catering catering


exhibitors

Company Booth

German Society Industrial Cell Technology Lübeck (D) 33

EBERS Medical Technology S.L. Zaragoza (ES) 27

eBioscience Vienna (A) 20

Edizioni Altera srl Rome (IT) 30

Ewald Innovationstechnik GmbH Bad Nenndorf (D) 1

Fraunhofer Group for Life Sciences Hanover (D) 7

Fraunhofer Institute for Cell Therapy and Immunology Leipzig (D) 7

Fraunhofer Institute for Interfacial Engineering and Biotechnology Stuttgart (D) 7

GE Healthcare Munich (D) 34

German Society for Regenerative Medicine e.V. Frankfurt / Main (D) 9

GeSim mbH Großerkmannsdorf (D) 29

Greiner Bio-One GmbH Frickenhausen (D) 21

Hiss Diagnostics GmbH Freiburg (D) 24

Hugo Sachs Elektronik – Harvard Apparatus GmbH March-Hugstetten (D) 43

InTech – Open Access Publisher Rijeka (HR) 8

Janvier SAS St Berthevin (FR) 41

Jenpolymers Ltd. Jena (D) 16

Labotect GmbH Göttingen (D) 47

Life Technologies GmbH Darmstadt (D) 3

MACHERY-NAGEL GmbH & Co. KG Düren (D) 42

Nikon GmbH Düsseldorf (D) 18

ORTHOGEN Lab Services GmbH Düsseldorf (D) 6

PAA Laboratories GmbH Cölbe (D) 23

PeproTech GmbH Hamburg (D) 15

pluriSelect GmbH Leipzig (D) 27a

Projektträger Jülich, Forschungszentrum Jülich GmbH Jülich (D) 4

PromoCell GmbH Heidelberg (D) 19

Regenerative Medicine Initiative Berlin-Brandenburg (RMIB) Berlin (D) 30a

R&D Systems GmbH Wiesbaden (D) 25

Roche Diagnostics GmbH Mannheim (D) 12

ROWIAK GmbH Hanover (D) 44

Scottish Stem Cell Network (SSCN) Ltd. Roslin, Midlothian (UK) 31

SERVA Electrophoresis GmbH Heidelberg (D) 38

Sysmex Digitana AG Horgen (CH) 17

Thermo Fischer Scientific Langenselbold (D) 13

Translational Centre for Regenerative Medicine (TRM) Leipzig Leipzig (D) 9

V-Care Biomedical GmbH Leipzig (D) 46

VetCell Kingham, Oxfordshire (UK) 26

Viscofan Bioengineering Weinheim (D) 14


Athersysi n c.

media Partners

sPonsors and exhibitors

Partners

Partners and sPonsors


media Partners and sPonsors

TECHNOLOGIES


bundesministerium für bildung und forsChung

Die Biowissenschaften haben in den letzten Jahren einen entscheidenden Beitrag zum

tieferen Verständnis des Lebens geleistet. Daraus ergeben sich neue Aufgaben und

Arbeitsfelder für das Bundesministerium für Bildung und Forschung (BMBF). Die Rege-

nerative Medizin ist eines dieser wichtigen Handlungsfelder, welches auch im aktuellen

Rahmenprogramm „Gesundheitsforschung“ der Bundesregierung verankert ist.

Um den komplexen transdisziplinären Anforderungen von der Forschung bis zur

klinischen Anwendung regenerativer Therapien gerecht zu werden, hat das BMBF

zusammen mit den zuständigen Landesministerien spezifische Translationszentren in

Berlin (BCRT), Leipzig (TRM) und Rostock (RTC) gegründet. Mit der Bekanntmachung zur

Förderung Bilateraler Verbundprojekte mit dem Californian Institute for Regenerative

Medicine (CIRM) zur Entwicklung und Validierung von Methoden und Verfahren für die

Regenerative Medizin wird zudem die Bedeutung der internationalen Zusammenarbeit

weltweit anerkannter Forschungsgruppen in der RegMed hervorgehoben. Diese Maß-

nahmen werden durch die „Nationale Forschungsstrategie BioÖkonomie 2030“ sowie

institutionelle Förderungen von außeruniversitären Forschungseinrichtungen, auch unter

Beteiligung der Wirtschaft, ergänzt.

Weitere Informationen und kompetente Beratung zu unseren Fördermaßnahmen und

Bekanntmachungen erhalten Sie über den Projektträger Jülich (PtJ).

www.ptj.de/regenerative-technologien


endorsing Partners

Tissue and Cell Engineering Society

endorsing Partners



ComPanies in saxony

sPeCial: ComPanies in saxony

the WorLD conference on regenerAtive meDicine iS kinDLy

SuPPorteD by the SAxony StAte miniStry for Science AnD the ArtS

Biosaxony alliance \\ www.biosaxony.com

The biosaxony alliance consits of biosaxony e.V and

biosaxony Management GmbH. biosaxony e.V. is a

registered association representing biotechnology and

related areas from materials science to medical equipment throughout the German region

of Saxony. The aims of biosaxony Management GmbH are to initiate projects between

industry and science, to network services and expertise, and to leverage synergies to

boost the development of the biotech industry and publicize the region’s expertise.

BIO-NET LEIPZIG Technologietransfergesellschaft mbH \\ Leipzig \\ www.bio-city-leipzig.de

Factors for sustainable growth of biomedical companies are favorable

structural and financial support and a network that has proven its value

and works on an interdisciplinary basis. That’s exactly what makes BIO

CITY LEIPZIG so unique. Here you can find everything that successful

biomedical businesses may need. BIO-NET LEIPZIG GmbH is your

partner of choice for business development, settlement, and R&D

networks in the area of Leipzig.

V-Care \\ Leipzig \\ www.v-care-biomedical.com

V-Care Biomedical GmbH provides high-quality, innovative products

from the field of regenerative medicine, as well as a strong emphasis on

service. This includes products from the field of regenerative medicine and

innovative wound treatment products for both people and animals.


Don´t miss the V-Care presentation:

Thursday, November 3, Session “Skin & Soft Tissue Regeneration“ (04:00–05:30 pm)

Titel “Update on ATMPs in veterinary medicine: From lab to patient´s site“

Presenter: Andreas Emmendörffer

Visit the V-Care booth at the exhibition area.

Prima BioMed GmbH \\ Leipzig \\ www.primabiomed.com.au

Prima BioMed GmbH is a subsidiary of the ASX

listed Australian health care company Prima BioMed

Ltd. The Company is focused on technologies in the

fields of cancer immunotherapy and immunology. Prima’s lead product is the CVac™

ovarian cancer therapy treatment. The Company’s broader, long term goal is to develop

commercial cancer treatment technologies and programs for global markets.

Don´t miss the Prima BioMed presentation:

Wednesday, November 2, Session “Signalling & Cancer“ (11:00 am–12:30 pm)

Titel “Autologous dendritic cells pulsed with recombinant human fusion protein [mucin

1-glutathione S-transferase] coupled to oxidized polymannose as maintenence treatment

of epithelial ovarian cancer in remission: A clinical trial update“

Presenter: Matthew Lehman

PluriSelect GmbH \\ Leipzig \\ www.pluriselect.com

PluriSelect provides customers in academic science,

research & development and diagnostics with

efficient tools for cell and protein separation. For each

segment, we develop separation tools to isolate target cells and / or proteins directly

from whole blood, buffy coat or other biological fluid. The cell and protein separation

tools developed by pluriSelect are versatile in application and form the basis of research

in cancer, rheumatic illnesses, arteriosclerosis and allergies.


ComPanies in saxony

GeSIM \\ Grosserkmannsdorf \\ www.gesim.de

GeSiM is a leading supplier of instrumentation and services for low-

volume liquid handling, microfluidics, and microcontact printing. Being

in business for more than 16 years, GeSiM focuses on off-the-shelf

products (E.g. non-contact micro arrayers) as well as tailored solutions.

Visit the GeSIM booth at the exhibition area.

Saxony Economic Development Corporation \\ Dresden \\ www.wfs.sachsen.de

The Saxony Economic Development Corporation

(WFS) builds bridges: For Saxon enterprises

heading off into the world and for investors

heading for Saxony. As an instrument of economic promotion, the WFS makes a vital

contribution to the sustained, positive development of Saxony’s economy. WFS activities

focus specifically on attracting innovative, competitive enterprises to Saxony, thus, safe-

guarding existing jobs and creating new ones, strengthening those enterprises which are

already located here by initiating sales promotion measures and arranging cooperations

as well as launching effective and efficient locational marketing campaigns.

Further saxony biotech companies will be represented by biosaxony at the

exhibition area:

\\ Vita34 AG, Leipzig, www.vita34.de

\\ PARTEC GmbH, Görlitz, www.partec.com

\\ Biotype Diagnostic GmbH, Dresden, www.biotype.de

\\ UroTec GmbH, Dresden, www.urotec.de

80 World Conference on Regenerative Medicine, November 2–4, 2011www.eventlab.org

We make your conference a success to remember.


information

general information

Conference Coordinator

Fraunhofer Institute for Cell Therapy

and Immunology

Professor Frank Emmrich

Perlickstr. 1 | D-04103 Leipzig

www.izi.fraunhofer.de

Conference Office

event lab. GmbH

Dufourstr. 15 | D-04107 Leipzig

phone: +49 163 4419072

fax: +49 341 240596-51

e-mail: [email protected]

Conference Dates | Opening Hours

Registration Desk

\\ Wednesday, November 2, 2011:

09:00 am–08:00 pm

\\ Thursday, November 3, 2011:

08:00 am–08:00 pm

\\ Friday, November 4, 2011:

08:00 am–06:00 pm

Speakers Preview

The Speakers preview room, lecture hall 12

(level +2), will be open all time during the

conference. Please come to the speakers

preview room as soon as possible and no

later than 30 minutes before your session

starts. Presentations will be collected

and delivered to the lecture hall via the

computer network.

Language

The official language of the conference is

English.

Participation / Name Tag

Official conference name tags will be

required for admission to all conference

functions, scientific sessions and exhibition

areas. Individuals who lose their name tags

will have to pay a fee of 30 € to obtain a

replacement tag.

Exhibition Information

The exhibition of the World Conference

on Regenerative Medicine, featuring

commercial displays of pharma ceutical and

product companies, medical publishers will

be located in the foyer area (level +1).

The exhibition will be open on:

\\ Wednesday, November 2, 2011:

11:00 am–08:00 pm

\\ Thursday, November 3, 2011:

09:00 am–05:30 pm

\\ Friday, November 4, 2011:

09:00 am–05:30 pm

The Get-together will take place in the

exhibition area on Wednesday evening.


Internet

Free of charge internet station can be

found on floor +2 in front of room 10/11.

W-LAN Vouchers can be purchased at the

registration desk (cash payment only).

\\ Voucher (3 hours): 5.00 €

\\ Voucher (1 day): 13.00 €

\\ Voucher (3 days): 30.00 €

Poster Presentation

The poster exhibition will take place on

level 0 in the Congress Center Leipzig.

The poster exhibition will be opened

all-day on the conference days. The Poster

Party, at which each presenter must be

available for discussion, will take place on

Thursday, November 3, 2011, at 5:30 pm..

Materials for putting up the posters will be

provided. Posters must be removed from

the board until the end of the conference.

The meeting staff will remove posters not

taken down by Friday, November 4, 2011,

and the meeting organizers cannot

take any further responsibility for the

material.

Public Transport

The official conference name tag allows

free use of the public transportation

system within Leipzig (including from / to

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Certification

The Medical Association of Saxony

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str.

ski-straße

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Rosental-gasse

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str.

Hinrichsenstraße

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Keilstraße

Packhof-str.

Am H

all.

Tor

Naun-

dörfchen

Thoma-

str.

sius-

straßeLessing-

Poniatowski-plan

C.-M.-v.

Weber-S

tr.

Mendels

sohnst

r.

Alexan-

derstr.

rstraße

Schreberstr.

Wilh.-

Se

Dimitroffstraße

Mar

kthall

en-

straß

e

Brüderstr.

straße-Sch

nel-

r-Str.

Leplay-str.

Jablon

owski

str.

Turne

r-str

.

1 Webergasse

Fried

richs

tr.

Sternwarte

Auguste-Schmidt-Str.An d.Verfassungs-lindeSee- burg- straße

Stern- wartenstraße

Ost-l

Amalie-Winter-Pl t

Joh.-al

leeTeubnerstr.Seemannstr.

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Johannisgasse

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straße Plato-

straß

e

berg

platz

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esstr

aße

1

Sche

rlstra

ße

Lang

e

Stra

ße

Ludw

ig-E

rhar

d-S

traße

Ranftsche G.Marien-platzAn

der

Milch

insel

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lstra

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onst

raße

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mon

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s

tr.Chopin- straße

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DörrienstraßeLittstraße

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hne-

kamm Ho

fmeis

ters

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Beckm.-Str.

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lstr.

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al-

straß

e

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Str.

3

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Klos

terg

.

F leis

cherg

asse

Kleine Fleischerg.

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1

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park W.-Leuschner-Platz

Roß-

Ring

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Wächterstraße Windm

-Allee

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alle-Str.

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berg

er

S

traße

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raße

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kort-

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dele

rring

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straße

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str.

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arin

enst

raße

MarketSquare

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kirchhof

Ditt

-

richr

ing

Barfußgäßchen

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Salzg.

Tröndlinring

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itz-

Str.

Uni

vers

itäts

-st

r.N

ikol

aist

raße

Brühl

Burg-platz

Pete

rsst

raße

Neu

-

mar

kt

R.-Wagner-Platz

Richard-Wagner-Str.

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platz Preußerg.Kupfergasse

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raße

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ldt-

straße

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fend

orfe

r

MainStationWilly-

Brandt-

Platz

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- s

traße

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bers

traße

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d-

stra

ße

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Stra

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rger

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F.-List-Platz

straße

ring

Augustus-platz

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rgi-

Johannis-platz

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icht

sweg

Schil- lerstr.

Goe

thes

traße

Ritte

rstr.

Brühl

GrimmaischerSteinweg

Que

r-

st

raße

Kreuz- straße

straß

e

Que

r-

st

r.

Ritterstr.

plat

z AlterJohannis-friedhof

Kleingarten-anlage

Johannistal

Kurt-Schumacher-

Str.

Preu

ßens

eite

4 4 Simson-platz

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Lurgenst.-Steg

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Wiese

Joh.-E

ck-

Str.

Step

han-

weg

Mecklenb. Str.

Sporthalle

Brüder-

Bauh 1

Institut fürMetereologie

Universität

West-platz

Böttcherg.

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Jahnallee

Ranstädter Steinweg

Sach

sen - seite

Dresdner Str.

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Dittri ch -

Grün

ewald

str.

Fritz-v.Harck-Anlage

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park

Leibnizweg Herre

nalle

e

e

Parthe

Primavesistraße

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berg

Springer-

Karl-Rothe-

S

traßeStraße

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tritz

sche

r Stra

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ner

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(geschlossen)

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lder

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zacs

traße

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straß

e

H.-Kapelle-Straße

Fliederhof

Rackw

itzer

str.

AdenaueralleeAm Goth. Bad

Rosa-

Luxemburg- S

traße

Kucheng.str.

Atrium-

str.

Eilen- burger

Täubchen-

Max-Planck-Inst.

Straße

Fe

d

Museen imGRASSI

Central-theater

SkalaHochschule fürMusik und Theater

Schulmuseum

BStU + Museum in der Runden Ecke

Antiken-museum

Mäd

ler-P

assa

ge

Messehofpassage

SpecksHof

CityHochhaus

MDR

Naturkunde-museum

ÄgyptischesMuseum

Auerbachs Keller

Zeitgeschicht-liches Forum

Musikschule

Kunstmuseumder Sparkasse

Peters-bogen

Bach-Archiv

Apotheken-museum

Universitäts-Campus-

Paulinum

Neues Augusteum,+Galerie

MensaamPark

Hörsaal-gebäude

Leibniz Forum

MoritzbasteiStadthaus

IHK

Feuer-wache

Mendelssohn-Haus

Praxisklinikam Johannisplatz

Löhrs Carré

Ev.-reformierte

Kirche

Stadt-bibl.

Lutherkirche

Amerik.Konsulat Polizei-

direktion

L d i htHGB

Galerie f. zeitgen. Kunst

Augustusplatz(in Bau)

Pete

rs-

stei

nweg

Gewandhaus

Oper

Haus desBuches

Erich

-Wein

ert-Straß

e

NeuesRathaus

AltesRathaus

Bundesverw.-gericht

MdbK

Löhr

str.

Lumumba-

Zum ArabischenCoffeebaum

Stadtge-schichtl.Museum

Paul-Gerhardt-Weg

Leibnizweg

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Prellerstraß

e

Fritz-

Seger-Str.

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Erfurter-Straße

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str.

Berggartenstraße

Marbachstr.

Schillerweg

Plat

nerstr.

Winkelstr.

3 2 1

Poeten-Menckestraße weg

Schlöß

chen

wg.

Turm

-gu

tstr.

gstr.

GohliserSchlösschen

Villa Ida

Schiller-haus

Bre

itenf

elde

r

Str.

cher

aße

Nat

onek

-st

raße

Magdeburger Straße

ritzs

cher

Str.

Sto

ckst

r.

Blumen- straße

Kanals

tr.str

aße

Mechler-

str.

Erlenstr.

Blochmannstr.

Lützo

w-

Auerbach-platz

Blumen- str.

Regi

nens

tr.

Sass

traße

Daumierstraße

Benedixstraße

Blochm.-str.

Freiligrathplatz

M.-Metzger-Str.

Gohlis-Arkaden

The- resien-

straßePetzscher Str.Hartz- straßeDes

saue

r Stra

ße

Anha

lter

Str.

Bernbg.

Straße

Ham

burger Straße

Mag

dale

nens

tr.

SchiebestraßeSchönefelder

Straße

Geibels

traße

Hambg. Str.

Gedikestraße

4Kleis

t-

Kunadstr.

Wilhelminenstr.

Rückert Str.W.-Sammet-

Straße

Schinkel-str.

Witt

enbe

rger

Stra

ße

Salzmannstr.

Berlin

er S

traße

1

Am Flügelrad Diesel-

straße

2

Heinickestraße3Dinterstr.

Mörike-str.

Coppistr.straße

str.

Lenau Str.

Dinter-

straße

Wolfener Straße Schorlem-

mer Straße

Friedensstr.

thal

er

S

traße

Lütz

owst

r.

EisenacherGothaer StraßeStraße

Georg-Schu-

mann-

Bleichert-

Straße

Delitz

sche

r Str.

Blumenstr.

Böhme-

str.

Elsbeth- straße

Cöthner Straße

1 Endnerstraße2 Knauerstraße3 Lüderstraße

Cöthner Straße

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en-

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stein-

straße

straße

Straße

Frickestraße

Kirch-platz

Ulrichst

r.

Preller-

Halberst.-Str.

Parth

e

Nordfriedhof

Alter

Israel.

Friedh.

Gohlis-Center

HTWK

Kleing. Hauschild

Zöllner-

Täubchenweg

Simon-Dubnow-Institut

HBFPromenadenOst

HBFPromenadenWest

Löhr sCarré

Brockhaus-zentrum

Commerz-bank

Forumam Brühl

IbisHotel

Augustus-platz Oper

Augustus-platz Gewandh.

Burg-platz

StädtischesKaufhaus

Karstadt-Warenhaus

Zentral-straße

Otto-Schill-Straße

Markt-galerie

H Tram

Wittenberger Str.

H Tram

Hamburger Str.

H Tram

Apelstr.

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baumstr.

H Tram

Menckestr.

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Nordplatz

H Tram

F.-Seger-Str.

H Tram G.-Schumann- /Lützowstr.

Str.

H Tram

S-Bhf.Gohlis

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G.-Schumann- /Lindenthaler Str.

S-Bhf. Coppiplatz

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Chausseehaus

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Winter-gartenstr.

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HBFWestseite

HauptbahnhofLVB Infopoint

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Gerichtsweg

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W.-Leuschner-Platz

H Tram

Wächterstr.

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Neues Rathaus

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Thomaskirche

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Westplatz

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Roßplatz

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H Tram

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Neurosymposium 2012

TOPICSNeuroregeneration, plasticity and rehabilitationWhat embryogenesis can teach us about regenerationImaging and novel diagnosticsNeurodegeneration in stroke, Alzheimer dementia, and agingVascular aspects of neurodegenerationBalancing immune responses in neurodegenerationThe Janus Face of reactive astrogliosisMitochondria as cellular targets for neuroprotectionSupporting lesioned and aging brains – future perspectivesStem cell therapies for strokeHot news on successful therapeutic translations

May 2–5, 2012 | Potsdam, GermanyTHE MAGDEBURG MEETING SERIES

7th International Symposium on

neurorepair-2012.deCONFERENCE COORDINATORS Johannes Boltze, Alexander Kranz, Daniel-Christoph WagnerFraunhofer Institute for Cell Therapy and Immunology, Leipzig Georg Reiser Otto-von-Guericke-Universität Magdeburg, Medizinische Fakultät, Institut für Neurobiochemie, MagdeburgKlaus Reymann Leibniz Institute for Neurobiology, Magdeburg

CONFERENCE OFFICEevent lab. GmbHDufourstr. 15D–04107 Leipzige-Mail: [email protected]: +49 341 24 05 96 -50fax: +49 341 24 05 96 -51

CONFERENCE VENUEKongresshotel Potsdamam Templiner Seeam Luftschiffhafen 1D–14471 Potsdam


information

world conference on regenerative medicine [Germany | Leipzig | October 23–25, 2013]

www.wcrm-leipzig.com

we regeneration

next event 2013

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