T D CHUGHEmeritus Professor (NAMS),Sr. ConsultantBLK Memorial HospitalNew Delhi
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“ Wrestling with Black Bear”
Torii Kiyomasu
(active 1696-1722)
“For the world does not yet censureThose who tread the path of Dreams”
Ono no Komachi
History of Influenza
“I had a little bird
Its name was Enza
I opened the window
And in-flu-enza”
• Structure of virus
• Seasonal Flu
• Mode of spread, definition of close contact
• Suspected, Probable, Confirmed cases
Present Status of Pandemic, 2009
• USA (August 6, 2009, 11AM ET)
– Reporting States: 50
– Hospitalized Cases: 6,506
– Deaths: 436
• India (August 12, 2009)
– Total Confirmed cases:1079
– Deaths: 14 (Pune: 7)
Biology of the Disease
• Incubation period
• Infectivity of virus
• Susceptibility to disinfectants
• Prevention: Chemo/immuno-prophylaxis
Laboratory Diagnosis
• Throat, nasal, naso-pharyngeal swabs
• Antigen Detection
• RT-PCR
• Viral Culture
• Antibody detection
Infection Control Measures
TAMIFLU• Oral, age, early, dose
• Neurological effects
• - 54% children
• Resistance
• - 0.33% adults, 4% children, 1.26 % overall
• - OPD: 0.5 % adults, 5.5% children
• - Hospitalized 18% children
• July 22,2009: 5 resistant
Future?
“ Life Must Go On”