Powerful Decision-Making Tools in Medical-Pharmaceutical Issues

Chemical, Biochemical, Cellular, Subcellular

BIOANALYTICAL CHEMISTRY

IMMUNOAFFINITY CAPILLARY ELECTROPHORESIS

EBF-2016

CONCLUSIONS 1. We are experiencing an unprecedented acceleration in the speed at which

breakthrough therapies arise from basic scientific discovery.

2. Bioanalysis platforms are crucial to monitor biomarkers of relevance to diagnosis,

prognosis and effectiveness of therapy.

3. Immunoaffinity capillary electrophoresis provides a rapid analysis of the fate of

drug products and the determination of a panel of biomarkers in biosamples.

4. The technique is simple, cost effective, and yields precise and accurate results.

5. Coupled to powerful detectors IACE becomes a very sensitive tool and facilitates

the characterization of the intact drug, degradation products (PTMs), metabolites

and isoforms.

EBF-2016 Journal of Chromatography B, 1021 (2016) 14–29

EBF-2016