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Hydrogenation & Catalysis Tools Catalytic (stirred and flow) Pressure Reactors High Pressure Chemistry www.helgroup.com
Hydrogenation & Catalysis
Tools
Catalytic (stirred and flow) Pressure ReactorsHigh Pressure Chemistry
www.helgroup.com
1
HigH THRoUgHPUT CaTalysT sCReening
Hydrogenation & Catalysis Tools www.helgroup.com >> 2
increase productivity with Hel’s Catalyst screening systems
CaTComplete units for hydrogenation and other high pressure reactions. CAT systems have been designed to provide a cost effective, simple and easy to use tool for high pressure reaction screening. They can be used directly on stirring hot plates or in oil baths.
Manual systems| 100bar/250ºC rated vessels (316SS or Hastelloy)| Valves and pressure guage to manually purge (e.g. inert) and then pressurise with reacting gas (e.g. hydrogen)| Place on any hot plate for heating/stirring| “Pocket” for thermocouple to monitor operating temperature
automated systemFully automated design based around 96 well Zinsser block
| Up to 96 x 1ml HPLC capped vials
| 35bar/200ºC | Magnetically stirred| Computer control for:
- Gas feed/venting - Temperature - Agitation - Pressure
Cat 24 24 x 2ml
Cat 96 96 x 1ml
CaT 7 and 24| Head fitted with coolant
connection| “Cold fingers” condense vapours
and minimize cross contamination
Cat 18 18 x 2ml
CaT 18| Uses 18 x 2ml HPLC vials (with or without
Septa) but without refluxing features
CaT 96
Cat 7 7 x 10ml or 7 x1ml
Closure
Cooled head
24 x 2ml vials
Heated area
Coolant in
Coolant out
Gas feed/vent internal temp
t t
RaPid PRoCess develoPMenT
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Hydrogenation & Catalysis Tools www.helgroup.com >> 4
CUsToM PaRallel PRoCess oPTiMisaTion
PolyBloCK or autoMaTe ii Flexible and customisable chemistry platforms. HEL’s PolyBloCK and autoMate ii platforms are designed to offer cost-effective, compact and modular solutions to each customer’s requirements. With in-house software, mechanical and electrical engineering capabilities as well as extensive chemistry and chemical engineering knowledge, we are able to provide our customers a flexible and innovative approach to their needs.
100ml and 300ml reactors (interchangeable), with overhead stirring 8 x high pressure, high temperature reactors with stirring
8 x 75ml high pressure reactors with complete gas feed/venting manifold and suspended mechanical agitation
4 x 300ml high pressure reactors, fully automated, with suspended mechanical stirring
Demanding applications made simple and reliable
Highlights| Interchangeable reactors| Wide temperature range (-80°C to 250°C or higher)| Separate monitoring and control of each zone| Range of options for feed of gas and liquid| Fully integrated, compact designs
Process Development with independent pressure and temperature measurement and control. Available with gas, solid and liquid dosing options, using fully stirred reactors, volumes from 16 to 300ml.
HigH PRessURe sCale-UP
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Hydrogenation & Catalysis Tools www.helgroup.com >> 6
ConTinUoUs Flow CHeMisTRy
FlowCaTA computer controlled platform for the development of continous flow chemical processes, running up to 200bar and 550°C. The flexible design allows scale up of both homogenous and hetrogenous chemistries in the same unit and can incorporate a combination of gas and liquid feeds.
Features & BeneFits
software| Full software control of pressure,
temperature and feed rates of liquid/gas| Edit conditions any time without stopping
High throughput operation| Possible to write recipes to automatically
cover a range of process conditions, running in sequence
| At the end of each run, product is sampled and the next run initiated
applications| Screen new chemistries, rapidly| Optimize yield, identify new catalysts| Use for small-scale production,
quickly and safely| Also includes Carbonylation, Polymerisation
Bio-Fuel Research, Fischer-Tropsch, Refinery Unit Operations
novel engineering features provide ease of use and quality data
| Control of feeds, temperature, pressure and sampling
| Real-time process data
gas & liquid Feeds
Product
sample
Tube Reactor
Pressure Control
t
t
tt
| 300°C (Higher Optional)
stanDarD liMits
| 100bar (200bar optional)
| 1 gas| 1 liquid
| Reactor diameter 6-24mm| Reactor length 150-500mm
Multiple heating zones to suit larger length reactors
CoMMents
Robust and precise control valve, suitable for liquids, gases and two-phase mixtures, provides back pressure control.
Optionally, any number of separate and independent feeds can be controlled.
Available in 316SS or Hastelloy.
Temperature
ParaMeter
Pressure
Feeds
Reactor sizes
t
Recycle option
Over the past 20 years we have developed expertise and become industry leaders in:
| Reaction hazards, calorimetry, vent sizing| Process development and optimisation | Dust and powder flammability| Other hazard consultancy services, including expert opinion, HAZOPS, DIERS, incident and accident investigation and professional training
ConsultanCy & testing serviCes
Hel ltd // uK e: [email protected] t: +44 20 8736 0640Hel inc // us e: [email protected] t: +1 609 912 1551Hel China // Beijing e: [email protected] t: +86 10 8210 1033Hel germany // Hamburg e: [email protected] t: +44 20 8736 0640Hel india // thane e: [email protected] t: +91 22 4153 3317Hel italia // Milan e: [email protected] t: +44 20 8736 0640Hel russia // Moscow e: [email protected] t: +44 20 8736 0640
aBout HelHel is an international company that specialises in research and pilot scale chemical reactors and related data logging/automation tools for process r&D in the pharmaceutical, fine chemical and petrochemical industries. established in 1987 and with clients worldwide our key strengths are:
Knowledgeable staff - highly qualified and experienced chemical engineers and chemistsQuality - underpinned by ISO9001 certification for over 16 yearsservice - choice of service contracts backed by established culture of unmatched client supportrange of products - both off-the-shelf and custom designs, manual and fully automated controls, low and high pressure/temperature applications, single and parallel/multi-vessel products
www.helgroup.com
