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D1 REX B KLINE CONCORDIA D. MODERATION, MEDIATION SEM ADVANCED
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Page 1: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

D1

REX B KLINE CONCORDIA D. MODERATION, MEDIATION

SEM ADVANCED

Page 2: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

D2

X

1 DM M

1 DY

Y

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moderation

mmr

mpatop

ics

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cpm

mod. mediation

med. moderation top

ics

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cma

cause × mediator

most general top

ics

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MMR

X, W, Y are continuous

XW carries interaction

ˆX W XW

Y B X B W B XW A

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Edwards, J. R. (2009). Seven deadly myths of

testing moderation in organizational

research. In C. E. Lance & R. J. Vandenberg

(Eds), Statistical and methodological myths

and urban legends: Doctrine, verity and

fable in the organizational and social

sciences (pp. 143–164). New York: Taylor &

Francis.

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Myth

You must center, to reduce extreme

collinearity

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Truth

Centering changes nothing

Optional, if 0 is not on scale

Center some, others not

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Myth

You must use hierarchical entry

Page 12: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

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Truth

Not required

Possibly misleading

Page 13: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

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Myth

You can ignore score reliability

Truth

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Truth

Score reliability is critical

rXX > .90

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D15

Myth

ˆX W XW

Y B X B W B XW A

X, W are “main effects”

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Truth

X, W are linear only

Page 17: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

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Myth

You can ignore curvilinear effects

Page 18: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

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Truth

Estimate X2 and W2, too

Page 19: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

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Myth

Small samples are fine

Page 20: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

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Truth

Large samples needed

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X W Y

2 10 5

6 12 9

8 13 11

11 10 11

4 24 11

7 19 10

8 18 7

11 25 5

M 7.125 16.375

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ˆ .112 .064 8.873Y X W

2 .033R

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X W x w Y

2 10 −5.125 −6.375 5

6 12 −1.125 −4.375 9

8 13 .875 −3.375 11

11 10 3.875 −6.375 11

4 24 −3.125 7.625 11

7 19 −.125 2.625 10

8 18 .875 1.625 7

11 25 3.875 8.625 5

M 7.125 16.375 0 0

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ˆ .112 .064 8.873Y X W

ˆ .112 .064 8.625Y x w

2 .033R

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4

5

6

7

8

9

Y

10

11

1 5 4

X

2 3 6 7 8 9 10 11

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4

5

6

7

8

9

Y

10

11

1 5 4

X

2 3 6 7 8 9 10 11

W < MW

W > MW

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Analyses

Y on X, W, XW

Y on x, w, xw

Y on X, W, XWres

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XWres (1)

1. Regress XW on X, W

2. Create XW

3. Create XWres = XW − XW

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XWres (2)

1. Regress XW on X, W

2. Save residuals

3. Rename as XWres

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X W x w

XW .747 .706 xw −.138 .050

XWres 0 0

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Products

BXW = Bxw = BXWres

Same interaction

Same R2

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Page 35: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

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ˆ .112 .064 8.873Y X W

Unconditional linear

2 .033R

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ˆ 1.768 .734 .108 3.118Y X W XW

2 .829R

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ˆ 1.768 .734 .108 3.118Y X W XW

If W ↑ 1pt,

slope Y on X ↓ .108

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ˆ 1.768 .734 .108 3.118Y X W XW

If X ↑ 1pt,

slope Y on W ↓ .108

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D39

100

15

200

25

30

W

0

5

10

15

20

Y

2 4 6 8 10 12 14

X

ˆ 1.768 .734 .108 3.118Y X W XW

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ˆ 1.768 .734 .108 3.118Y X W XW

Conditional linear

Slope, Y on X is 1.768, if W = 0

Slope, Y on W is .734, if X = 0

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Centering

x = X − MX, w = W – MW

x = 0 says X = MX

w = 0 says X = MW

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ˆ .112 .064 8.625Y x w

2 .033R

ˆ .000 .035 .108 8.903Y x w xw

2 .829R

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ˆ .112 .064 8.873Y X W

2 .033R

resˆ .112 .064 .108 8.873Y X W XW

2 .829R

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Simple regressions

Simple slopes

Simple intercepts

Generate equations

Page 45: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

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Y on X as a function of W

ˆ 1.768 .734 .108 3.118Y X W XW

ˆ 1.768 .108 .734 3.118Y X XW W

ˆ (1.768 .108 ) .(734 3.118)Y W X W

Page 46: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

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ˆ (1.768 .108 ) .(734 3.118)Y W X W

16.38W

M

4.34 10.36 16.38 22.40 28.42

Page 47: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

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ˆ (1.768 .108 ) .(734 3.118)Y W X W

22.40ˆ .651 13.324

WY X

Page 48: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

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W

Level Score Regression equation

+2 SD 28.42 ˆ 1.301 17.712Y X

+1 SD 22.40 ˆ .651 13.324Y X

Mean 16.38 ˆ .001 8.905Y X

−1 SD 10.36 ˆ .649 4.486Y X

−2 SD 4.34 ˆ 1.299 .068Y X

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D49 1 5 4

X

2 3 6 7 8 9 10 11 4

5

6

7

8

9

Y

10

11

MW

−2 SDW

+SDW

−SDW

+2 SDW

Page 50: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

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MW

+1 SDW

+2 SDW

−1 SDW

−2 SDW

http://graph.seriesmathstudy.com/

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Other horizons

X, W, XW

X, X2, W, W2, XW

X, X2, W, W2, XW, X2W

Page 52: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

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Other horizons

X, W, Z, XW, XZ, WZ, XWZ

E.g., XW over Z

Really?

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Dawson, J. F., & Richter, A. W. (2006). Probing

three-way interactions in moderated

multiple regression: Development and

application of a slope difference test.

Journal of Applied Psychology, 91, 917–926.

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(a) Regression perspective

BX

BW

BXW

Y

1 D

X

XW

W

(b) Compact symbolism

BX

BW

BXW

Y

1 D

X

W

Page 55: ADVANCED SEM · Introduction to mediation, moderation, and process control analysis: A regression-based approach. New York: Guilford. D66 CPM Mediated moderation Moderated mediation

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(d) W as focal variable,

X as moderator

BW

BX BXW

W

X

Y

1 D

(c) X as focal variable,

W as moderator

BX

BW BXW

X

W

Y

1 D

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X

W

Y

1 D

X

W

Y

1 D

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D58

Kline, R. B. (2015). The mediation myth. Basic

and Applied Social Psychology, 37, 202–

213.

Little, T. D. (2013). Longitudinal structural

equation modeling. New York: Guilford.

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Design

Time precedence: X → M → Y

Experimental X

What about M → Y?

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D60

MacKinnon, D. P., & Pirlott, A. G. (2015). Statistical

approaches for enhancing causal interpretation

of the M to Y relation in mediation analysis.

Personality and Social Psychology Review, 19,

30–43.

Stone–Romero, E. F., & Rosopa, P. J. (2011).

Experimental tests of mediation models:

Prospects, problems, and some solutions.

Organizational Research Methods, 14, 631–646.

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Design

Time precedence: X → M → Y

Longitudinal

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M1

O1

X1

1 D12

M2

O2

1 D22

a

b

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Selig, J. P., & Preacher, K. J. (2009).

Mediation models for longitudinal data in

developmental research. Research in

Human Development, 6, 144–164.

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No design

Indirect effect

Mediation

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Hayes, A. F. (2013a). Conditional process modeling:

Using structural equation modeling to examine

contingent causal processes. In G. R. Hancock & R.

O. Mueller (Eds.), Structural equation modeling: A

second course (2nd ed.) (pp. 219–266). Greenwich,

CT: IAP.

Hayes, A. F. (2013b). Introduction to mediation,

moderation, and process control analysis: A

regression-based approach. New York: Guilford.

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CPM

Mediated moderation

Moderated mediation

Cause × mediator

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Mediated moderation

W

Y

1 DY

X

1 DM

M

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Lance, C. E. (1988). Residual centering,

exploratory and confirmatory moderator

analysis, and decomposition of effects in

path models containing interaction

effects. Applied Psychological

Measurement, 12, 163–175.

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Moderated mediation (1)

1st-stage moderation, X → M → Y

X → M depends on W

W

Y

1 DY

X

1 DM

M

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Mediated moderation (2)

1st-stage moderation, W → M → Y

W → M depends on X

W

Y

1 DY

X

1 DM

M

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Moderated mediation

2nd-stage moderation, X → M → Y

M → Y depends on W

X

W

M 1

DM

Y

1 DY

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Edwards, J. R., & Lambert, L, S. (2007).

Methods for integrating moderation and

mediation: A general analytical

framework using moderated path

analysis. Psychological Methods, 12, 1–22.

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Curran, T., Hill, A. P., & Niemiec, C. P. (2013).

A conditional process model of children's

behavioral engagement and behavioral

disaffection in sport based on self-

determination theory. Journal of Sport &

Exercise Psychology, 35, 30–43.

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Desrosiers, A., Vine, V., Curtiss, J., &

Klemanski, D. H. (2014). Observing

nonreactively: A conditional process

model linking mindfulness facets,

cognitive emotion regulation strategies,

and depression and anxiety symptoms.

Journal of Affective Disorders, 165, 31–37.

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Hayes, A. F., & Preacher, K. J. (2013).

Conditional process modeling: Using

structural equation modeling to examine

contingent causal processes. In G. R.

Hancock & R. O. Mueller (Eds.), Structural

equation modeling: A second course (2nd

ed.) (pp. 219–266). Greenwich, CT: IAP.

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Baron-Kenny

Continuous variables

Linear model

No interaction

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a

b c

X M

1 DM

Y

1 DY

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Product estimator

X → M, X → Y, M → Y

No omitted confounders

rXX = 1.0

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X

Y

1 DY

M

1 DM

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1 1M B X A

2 3 4 2Y B X B M B XM A

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X × M

No single direct

No single indirect, total

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X × M

Effect decomposition?

Nonlinear models?

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D86

Pearl, J. (2014). Interpretation and

identification of causal mediation.

Psychological Methods, 19, 459–481.

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Causal mediation

Assumes X × M

Linear or nonlinear

Total = direct + indirect

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Causal mediation

Counterfactuals

What if Tx were not treated?

What if Cn were treated?

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Counterfactuals

Rubin Causal Model

Missing data inference

Latent variables

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Example

Experimental X = 0, 1

M, Y are continuous

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Direct effects

Controlled (CDE)

Natural (NDE)

No X × M? CDE = NDE

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CDE

How much Y changes

As X = 0 to X = 1

If M = m for all cases

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CDE

Estimate for m = M

Policy: Lift all to m

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NDE

How much Y changes

As X = 0 to X = 1

If M varies as under X = 0

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NIE

How much Y changes in X = 1

As M changes from in

X = 0 to X = 1

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Total Effect

TE = NDE + NIE

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Counterfactuals

CDE = E [ Y (X = 1, M = m) ] – E [ Y (X = 0, M = m) ]

NDE = E [ Y (X = 1, M = m0) ] – E [ Y (X = 0, M = m0) ]

NIE = E [ Y (X = 1, M = m1) ] – E [ Y (X = 1, M = m0) ]

TE = E [ Y (X = 1) ] – E [ Y (X = 0) ]

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Petersen, M. L., Sinisi, S. E., & van der Laan,

M. J. (2006). Estimation of direct causal

effects. Epidemiology, 17, 276–284.

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X = 0, control; X = 1, AVT

M = viral load

Y = CD4 T-cells

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CDE

Mean Δ T-cells if viral load were

the same for all cases

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NDE

Mean Δ T-cells if viral load were

as among untreated cases

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NIE

Mean Δ T-cells among treated if

viral load changed from

untreated to treated levels

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0 1ˆ β βM X

0 1 2 3ˆ θ θ θ θY X M XM

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1 3CDE θ θ m

1 3 0NDE θ θ β

2 3 1NIE (θ θ )β

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0 1 2 3ˆ θ θ θ θY X M XM

If θ3 = 0:

1CDE θ

1NDE θ

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ˆ 1.70 .20M X

ˆ 450.00 50.00 20.00 10.00Y X M XM

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β0 = 1.70 and β1 = −.20

θ0 = 450.00,

θ1 = 50.00, θ2 = −20.00,

and θ3 = −10.00

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CDE = 50.00 − 10.00 m

NDE = 50.00 − 10.00 (1.70) = 33.00

NIE = (−20.00 − 10.00) −.20 = 6.00

TE = 33.00 + 6.00 = 39.00

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Valeri, L., & VanderWeele, T. J. (2013).

Mediation analysis allowing for exposure–

mediator interactions and causal

interpretation: Theoretical assumptions

and implementation with SAS and SPSS

macros. Psychological Methods, 2, 137–

150.

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Imai, K., Keele, L., & Tingley, D. (2010). A

general approach to causal mediation

analysis. Psychological Methods, 15, 309–

334.

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