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Back Matter Source: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, No. 8 (Apr. 13, 1999), pp. xi-xx Published by: National Academy of Sciences Stable URL: http://www.jstor.org/stable/47635 . Accessed: 06/05/2014 10:35 Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at . http://www.jstor.org/page/info/about/policies/terms.jsp . JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact [email protected]. . National Academy of Sciences is collaborating with JSTOR to digitize, preserve and extend access to Proceedings of the National Academy of Sciences of the United States of America. http://www.jstor.org This content downloaded from 130.132.123.28 on Tue, 6 May 2014 10:35:13 AM All use subject to JSTOR Terms and Conditions
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Page 1: Back Matter

Back MatterSource: Proceedings of the National Academy of Sciences of the United States of America,Vol. 96, No. 8 (Apr. 13, 1999), pp. xi-xxPublished by: National Academy of SciencesStable URL: http://www.jstor.org/stable/47635 .

Accessed: 06/05/2014 10:35

Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at .http://www.jstor.org/page/info/about/policies/terms.jsp

.JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range ofcontent in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new formsof scholarship. For more information about JSTOR, please contact [email protected].

.

National Academy of Sciences is collaborating with JSTOR to digitize, preserve and extend access toProceedings of the National Academy of Sciences of the United States of America.

http://www.jstor.org

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Page 2: Back Matter

AUTHOR INDEX, APRIL 13, 1999

Aaku-Saraste, E. 4639 Abernethy, J. 4680 Adams, P. D. 4325 Agrawal, R. K. 4301 Ahmad, N. 4524 Aisen, M. I., 4645 Akama, K. T. 4668 Akaza, T. 4581 Alitalo, K. 4546 Alonso-Blanco, C. 4710 Altan, N. 4432 Amar, S. 4518 Amster-Choder, 0. 4336 Ando, T. 4592 Angus, L. M. 4627 Anthony, D. D. 4524 Ariad, S. 4546 Arnot, D. E. 4506 Aronov, A. M. 4273 Arya, D. P. 4384 Au, H. C. 4354 Avivi, A. 4455 Baca-DeLancey, R. R. 4610 Badr, K. F. 4378 Bair, K. W. 4325 Baker, K. 4325 Ball, D. W. 4540 Ball, G. F. 4674 Bandy, D. 4569 Baruch, D. I. 4563 Bates, G. P. 4604 Baylin, S. B. 4540 Belli, B. A. 4598 Belyakov, I. M. 4512 Bender, J. R. 4313 Bentley, G. E. 4674 Berzofsky, J. A. 4512 Blankestijn-de Vries, H. 4710 Bonabeau, E. 4472 Bono, J.-J. 4704 Bornstein, P. 4449 Boshoff, C. 4546 Boudreau-Lariviere, C. 4627 Branellec, D. 4262 Bruice, T. C. 4384 Buckner, F. S. 4273 Bureau, M. F. 4262 Burley, S. K. 4342 Burrola, P. 4633 Caillaud, J.-M. 4262 Cantley, L. C. 4240 Canut, H. 4704 Castleman, A. W., Jr. 4219 Center, R. J. 4319 Chakravarty, S. 4256 Chan, R. Y. Y. 4627 Chang, S. M. W. 4598 Chao, D. 4581 Chauvet, M.-T. 4330 Chen, C.-F. 4443 Chen, K. 4569 Chen, P.-L. 4443 Chen, Y. 4432, 4443, 4724 Chen, Y.-N. P. 4325 Choi, S. K. 4342 Chzhan, M. 4586 Clemons, W. M., Jr. 4301 Codazzi, F. 4686 Collinge, M. 4313 Colussi, P. A. 4307 Conway, D. J. 4506 Corvol, P. 4330 Cotton, J. 4330 Craske, M. 4426 Cronan, J. E., Jr. 4360 Cullimore, J. 4704 Cuniasse, P. 4330)

Curtis, C. F. 4506 Dagorn, L. 4472 Daldal, F. 4348 Dale, J. 4552 Danishefsky, S. J. 4256 Davis, S. J. 4289 Day, K. P. 4563 Delaere, P. 4262 Deretic, D. 4633 Desai, B. N. 4438 Desplan, C. 4461 Deutscher, M. P. 4372 Dever, T. E. 4342 Dieleman, S. J. 4478 Ding, X. 4610 Dive, V. 4330 Dorstyn, L. 4307 Driguez, H. 4704 Driver, D. A. 4598 Drouillard, S. 4704 Dubensky, T. W., Jr. 4598 Dudek, T. 4558 Dupin, N. 4546 Dupuis, D. E. 4402 Duret, L. 4482 Editorial Board, 4215 Egelman, E. H. 4279 Eisenberg, D. 4285 Escande, J.-P. 4546 Essex, M. 4558 Evrard, A. E. 4228 Fan, W. 4313 Fesik, S. 4552 Fisher, C. 4546 Fisher, G. H. 4552 Forchhammer, M. C. 4467 Franck, N. 4546 Frank, G. 4420 Frank, J. 4301 Fr6on, P. 4472 Fresco, J. R. 4500 Frolov, I. 4598 Fujiyama, K. 4692 Fukutake, K. 4581 Gautier, J.-F. 4569 Gehi, J. 4262 Gelb, M. H. 4273 George, C. X. 4621 Gerasimenko, 0. 4426 Gerchman, S. E. 4301 Geremia, R. A. 4704 Gessler, K. 4246 Ghosh, S. 4372 Givol, D. 4455 Gorin, I. 4546 Gorivodsky, M. 4455 Goto, M. 4581 Graff, J. R. 4540 Grassucci, R. A. 4301 Graves, K. H. 4575 Greenberg, E. P. 4360 Greenwood, B. M. 4506 Gressent, F. 4704 Grobusch, M. P. 4506 Gruissem, W. 4718 Guilford, W. H. 4402 Gummer, A. W. 4420 Gupta, S. 4524 Hanhart, C. J. 4710 Hanzelka, B. L. 4360 Haqqi, T. M. 4524 Hardwick, J. S. 4438 Hariharan, M. J. 4598 Harlos, K. 4289 Harter, K. 4718 Hasenbanlk, R. 4604 Hayk, H. 4455

Hayward, R. E. 4563 He, G. 4586 He, L. 4256 Heckman, J. J. 4730 Hedden, P. 4698 Heiser, V. 4604 Hemmert, W. 4420 Hine, A. V. 4295 Hiraiwa, N. 4530 Hoffman, A. S. 4449 Hogan, N., 4645 Hol, W. G. J. 4273 Holzman, P. S. 4724 Homanics, G. E. 4680 Horwitz, S. B. 4256 Hoyt, D. G. 4680 Huang, B. 4552 Hurley, S. M. 4219 Huttner, W. B. 4639 Hyberts, S. G. 4295 lacopetti, P. 4639 Ikemizu, S. 4289 Improta-Brears, T. 4686 Inoue, T. 4256 Ishikawa, Y. 4581 Iwamoto, A. 4581 Jackson, C. E. 4552 Janody, F. 4461 Jasmin, B. J. 4627 Jiang, L. 4325 Jiracek, J. 4330 Jolly, D. J. 4598 Jones, E. Y. 4289 Josaitis, C. A. 4390 Juji, T. 4581 Kaelin, W. G., Jr. 4325 Kamat, A. 4575 Kanamori, A. 4530 Kandel, E. R. 4650 Kannagi, R. 4530 Kannan, K. 4455 Kansas, G. S. 4530 Kay, C. M. 4366 Kelavkar, U. P. 4378 Kellam, P. 4546 Kemp, B. E. 4319 Keszthelyi, L. 4252 Kim, M. J. 4488 Kim, S. 4488 Kimura, N. 4530 Kimura, Y. 4692 Kirshner, R. P. 4224 Klein, C. A. 4494 Klein, E. 4680 Kobe, B. 4319 Koornneef, M. 4710 Krammer, P. H. 4552 Krappa, R. 4633 Krause, M. 4662 Krauss, N. 4246 Krebs, H. I., 4645 Kremsner, P. G. 4506 Kudla, J. 4718 Kuduk, S. D. 4256 Kulcsar, A. 4408, 4414 Kumar, G. K. 4524 Kumar, S. 4307 Kuppusamy, P. 4586 Kusakabe, T. 4295 Kyriakides, T. R. 4449 Langvatn, R. 4467 Lanyi, J. K. 4408, 4414 Lawson, M. 4569 Lazo, J. S. 4680 Leach, K. J. 4449 Lebo, R. 4518 Lee, B.-S. 4390

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AUTHOR INDEX, APRIL 13, 1999

Lee, J. H. 4342 Lee, J. S. 4488 Lee, M.-S. 4524 Lee, T.-H. 4558 Lee, W.-H. 4443 Lees, J. A. 4221 Lehrach, H. 4604 Leisinger, T. 4615 Lemke, G. 4633 Lenardo, M. J. 4552 Levy, D. L. 4724 Li, Z. 4279 Li, Z.-W. 4656 Lin, S. 4256 Lipp, H.-P. 4656 Liu, H. 4581 Liu, Y.-C. 4313 Lonai, P. 4455 Loss, C. 4461 Lowey, S. 4402 Luan, S. 4718 Lurz, R. 4604 McCune, B. K. 4540 McCutcheon, J. P. 4301 McDonnell, D. P. 4686 McDowell, P. R. 4540 McGregor, L. M. 4540 Magara, F. 4656 Mahoney, M. J. 4536 Mankal, F. A. 4627 Mansuy, I. 4650 Mantegazza, N. 4704 Marcotte, E. M. 4285 Mariko, Y. 4592 Martin, D. A. 4552 Martin, M. S. 4325 Maruyama, Y. 4581 Matsuno-Yagi, A. 4354 Matthysse, S. 4724 Mendelson, C. R. 4575 Mento, S. J. 4598 Messmer, M. 4615 Meyer, T. 4686 Michaud, A. 4330 Michelini, M. 4639 Mir, L. M. 4262 Mitsuoka, C. 4530 Moss, B. 4512 Motegi, H. 4488 Mouchiroud, D. 4482 Mukhtar, H. 4524 Muiller, U. 4656 Muramatsu, T. 4530 Myers, S. T. 4236 Myllykallio, H. 4348 Myokai, F. 4518 Nagai, Y. 4581 Nakamura, T. 4581 Nakanishi, 0. 4592 Nakayama, E. E. 4581 Nakayama, K. 4724 Narayanaswami, V. 4366 Neel, B. G. 4240 Nelkin, B. D. 4540 Nguyen, A. 4633 Niebel, A. 4704 Nomura, M. 4390 Nosaka, Y. 4592 Nussbaum-Shochat, A. 4336 Oback, B. 4639 Oduola, A. M. J. 4506 Ohishi, T. 4581 Ojima, I. 4256 Okada, S. 4246 Opperdoes, F. R. 4273 Palacpac, N. Q. 4692 Pan, J. 4313

Pantel, K. 4494 Parmentier, H. K. 4478 Parsek, M. R. 4360 Passy, S. I. 4279 Patlak, J. B. 4402 Pedarzani, P. 4662 Pellegrini, M. 4285 Perri, S. 4598 Peter, M. E. 4552 Petersen, 0. H. 4426 Peterson, R. T. 4438 Petrova, T. V. 4668 Philips, S. M. 4301 Phillips, A. L. 4698 Pines, M. 4455 Piper, K. P. 4563 Polo, J. M. 4598 Post, E. 4467 Poumbourios, P. 4319 Pratley, R. E. 4569 Puck, J. M. 4552 Quinn, L. M. 4307 Radding, C. M. 4279 Ramakrishnan, V. 4301 Ramsey, T. M. 4325 Rangara, R. 4262 Ranjeva, R. 4704 Rather, P. N. 4610 Ratner, B. D. 4449 Ravussin, E. 4569 Reiman, E. M. 4569 Rho, S. B. 4488 Richardson, C. C. 4295 Richardson, H. 4307 Richardson, J. A. 4575 Riethmuiller, G. 4494 Roll-Mecak, A. 4342 Romans, K. E. 4540 Roper, C. 4506 Rouy, D. 4262 Ryan, R. 0. 4366 Saenger, W. 4246 Saito, A. 4592 Saito, H. 4581 Sakai, H. 4692 Salbe, A. D. 4569 Salmon, D. 4546 Saltiel, J. 4408, 4414 Saltzman, W. M. 4536 Samain, E. 4704 Samouilov, A. 4586 Samuel, C. E. 4621 Schaeffer, V. 4461 Schardt, J. A. 4494 Scheffler, I. E. 4354 Scherman, D. 4262 Scherzinger, E. 4604 Schieve, D. 4366 Schindler, M. 4432 Schlesinger, S. 4598 Schmidt-Kittler, 0. 4494 Schreiber, S. L. 4438 Schwartz, B. 4262 Schwartz, D. R. 4680 Schweiger, K. 4604 Sears, D. F., Jr. 4408, 4414 Seidman, J. 4650 Seki, T. 4692 Seo, B. B. 4354 Seol, W. 4488 Shankar, R. A. 4586 Shapiro, R. 4396 Sharma, S. K. 4325 Sharp, Z. D. 4443 Sheldrick, G. M. 4246 Sherrill, 5. 4598 Shiba, K. 4488

Shioda, T. 4581 Siddiqi, I. 4390 Siegel, R. M. 4552 Simon, S. M. 4432 Sittler, A. 4604 Smith, M. E. 4575 Smith, S. M. 4246 Sobel, R. A. 4650 Son, H. 4650 Sonoda, S. 4581 South, M. M. T. 4610 Sowers, L. C. 4500 Sparks, L. M. 4289 Spatz, M. K. 4455 Speicher, M. R. 4494 Spiro, T. G. 4500 Stagljar, M. 4656 Steidel, C. C. 4232 Stenseth, N. C. 4467 Stocker, M. 4662 Straus, S. E. 4552 Strober, W. 4512 Stuart, D. I. 4289 Stuckmann, I. 4639 Studer, A. 4615 Suen, W. 4500 Suresh, S. 4273 Suzuki, T. 4592 Szabao-Nagy, A. 4252 Taguchi, H. 4581 Takaha, T. 4246 Takamatsu, J.-k. 4581 Takashiba, S. 4518 Takebe, Y. 4581 Takeo, T. 4426 Tamatani, T. 4530 Tataranni, P. A. 4569 Tepikin, A. V. 4426 Thomas, S. G. 4698 Thompson, M. J. 4285 Tiwari, B. 4563 Tor6k, K. 4426 Townsend, K. 4598 Trewavas, A. 4216 Trybus, K. M. 4402 Tsuchiya, K. 4592 Tsuruo, T. 4592 Tulliez, M. 4546 Tyska, M. J. 4402 Uchimura, K. 4530 Uecker, A. 4569 Us6n, I. 4246 Vaillant, C. 4426 Val, D. L. 4360 van der Merwe, P. A. 4289 Van Eldik, L. J. 4668 van Marck, E. 4546 Vannelli, T. 4615 Van't Hof, T. J. 4674 Van Voorhis, W. C. 4273 Vassiliou, S. 4330 Vazeux, G. 4330 Verhulst, S. 4478 Verlinde, C. L. M. J. 4273 Volpe, B. T., 4645 Vu, L. 4390 Vuilleumier, S. 4615 Vytlacil, E. J. 4730 Waller, G. S. 4402 Wang, J. 4366, 4552 Wang, W.-K. 4558 Wang, Y. 4455 Wanker, B. B. 4604 Warner, D. R. 4268

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Page 4: Back Matter

AUTHOR INDEX, APRIL 13, 1999

Warshaw, D. M. 4402 Weinberg, R. A. 4221 Weinstein, L. S. 4268 Weiss, R. A. 4546 Weissman, S. M. 4313 Weissmann, C. 4656 Whorton, A. R. 4686 Wimmer, E. A. 4461 Wolfer, D. P. 4656 Xin, X. 4581

Xu, Q. 4718 Yagi, T. 4354 Yamashita, T. 4592 Yancopoulos, G. D. 4540 Yashiki, S. 4581 Yayon, A. 4455 Yeates, T. 0. 4285 Yiotakis, A. 4330 York, J. D. 4686 Yoshida, S. 4692

Yoshida, T. 4692 Yu, X. 4279 Zannoni, D. 4348 Zhang, C. 4313 Zhang, W. 4650 Zheng, L. 4552 Zhong, Q. 4219 Zhuo, M. 4650 Zimanyi, L. 4408, 4414 Zweier, J. L. 4586

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Page 5: Back Matter

Proc. Natl. Acad. Sci. USA Vol. 96, April 1999

INFORMATION FOR AUTHORS

(Revised February 1999)

PURPOSE AND SCOPE

The PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES

USA (PNAS) publishes research reports, commentaries, and colloquium papers. In accordance with the guiding principles established by George Ellery Hale in 1914, PNAS publishes brief first announcements of Academy Members' and Foreign Asso- ciates' (hereafter referred to as Members) more important con- tributions to research and of work that appears to a Member to be of particular importance. PNAS is a general science journal with a broad scientific audience. All papers should be intelligible to this audience.

RESEARCH REPORTS describe the results of original research of exceptional importance.

COMMENTARIES call attention to papers of particular note and are written at the invitation of the Editorial Board.

COLLOQUIUM PAPERS are reports of scientific colloquia held under Academy auspices.

EDITORIAL POLICIES

Submission and Review

Manuscripts may be submitted to PNAS through any of the following three tracks:

Track I. An Academy Member may "communicate" manu- scripts for others that are within the Member's area of expertise. Prior to submission to PNAS, the Member obtains reviews of the paper from at least two qualified referees, each from a different institution and not from the authors' institutions.

Track II. Authors (Members or non-Members) may submit their manuscripts directly to the PNAS office. In a cover letter, authors must name five Members who are expert in the paper's scientific area. The Editorial Board may choose a Member as editor for the paper who is not on that list. The Member-editor conducts the review of the paper as described for Track I. A list of Members including research interests is on the PNAS Home Page (see NAS Members): www.pnas.org. Authors may also suggest qualified referees. The name of the Member-editor, who may remain anonymous to the author until the paper is accepted, will be published in PNAS as editor of the article.

Track III. An Academy Member may submit his or her own manuscripts for publication. Members' submissions must be accompanied by the name of knowledgeable colleague(s) who reviewed the paper.

All Tracks. Manuscripts submitted under any of the three tracks are evaluated by the Editorial Board. The Board may reject manuscripts without further review or may subject manuscripts to review and reject those that do not meet the standards of the journal. Manuscripts rejected by one Member cannot be resubmitted through another Member. When revi- sions are requested prior to final decision, revised papers must be received within three months or they will be treated as new submissions.

In the journal, Track I, II, and III papers are distinguished respectively as "Communicated by," "Edited by," and "Con- tributed by" the responsible Member. Track II papers have an additional identifying footnote.

Journal Policies

(i) Articles are accepted provided they have not been PUB- LISHED PREVIOUSLY or concurrently submitted for publication elsewhere. Three copies of any closely related manuscripts in press or submitted for publication elsewhere by the authors must be included.

Figures or tables that have been published elsewhere must be identified, and permission of the copyright holder for both the print and the online editions of the journal must be provided.

(ii) AUTHORSHIP should be limited to those who have contrib- uted substantially to the work. The corresponding author must have obtained permission from all authors for the submission of each version of the paper and for any change in authorship.

(iii) All authors and Members must disclose any commer- cial association that might pose a CONFLICT OF INTEREST in connection with the manuscript. All funding sources support- ing the work must be acknowledged.

(iv) A completed form assigning COPYRIGHT to the National Academy of Sciences must be returned to the PNAS office before the paper can be published. This and other forms are available in the back of each issue and at www.pnas.org.

(v) The Academy may distribute EMBARGOED copies of an article to the press prior to publication.

(vi) Research involving HUMAN AND ANIMAL SUBJECTS must have been approved by the author's institutional review board. All clinical investigation must have been conducted according to the principles expressed in the Declaration of Helsinki.

(vii) For research using RECOMBINANT DNA, physical and biological containment must conform to National Institutes of Health guidelines or those of a corresponding agency.

(viii) Authors must make UNIQUE MATERIALS (e.g., cloned DNAs; antibodies; bacterial, animal, or plant cells; viruses; and computer programs) promptly available on request by quali- fied researchers for noncommercial use.

(ix) DATABASES: Accession codes must be supplied for publication. A footnote indicating that the data have been deposited will be added to the paper.

Protein and Nucleic Acid Sequences: Authors should submit manuscripts containing nucleotide sequences to GenBank/ EMBL/DNA Data Bank of Japan (DDBJ) at GenBank, National Center for Biotechnology Information, 8600 Rockville Pike, Building 38A, Room 8N-803, Bethesda, MD 20894 USA. Phone: (301) 496-2475. E-mail (submissions): [email protected]. E-mail (information): [email protected]. An accession num- ber must be obtained before the manuscript is printed.

Structures of Oligonucleotides: Authors must deposit these data directly with the Nucleic Acid Database or its equivalent at [email protected].

Structural Studies: Authors of papers describing new struc- ture determinations must submit to the Protein Data Bank at Brookhaven National Laboratory or its equivalent, all struc- tural data required to validate the discussion, including x-ray amplitudes and the derived atomic coordinates. For nuclear magnetic resonance structures, data deposited should include resonance assignments and all restraints used in structure determination and the derived atomic coordinates for both an individual structure and a family of acceptable structures. Articles must include literature references for all coordinate datasets as well as dataset identification. Authors must agree to release the coordinates when the article is published.

(x) SUPPLEMENTARY MATERIAL: Supplementary Material provides a way to enhance papers in PNAS by providing additional substantive data. Supplementary Material is re- viewed along with the paper but instead of appearing in the printed version of the journal, it is distributed via the PNAS web site (www.pnas.org) at the time of publication. Supple- mentary Material is referred to at the appropriate point in the

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Page 6: Back Matter

Information for Authors Proc. Natl. Acad. Sci. USA 96 (1999) xv

text and cannot be altered by authors after papers have been accepted.

Supplementary Material may take the form of supporting figures, tables, datasets, derivations, and videos. Authors should express their interest in their cover letter to include Supplementary Material with their paper. In addition, editors may suggest that part of the submitted data could be more suitably presented online only to save journal space and to focus the article. (Details available on request from pnas@ nas.edu.)

PROCEDURES FOR SUBMITTING MANUSCRIPTS

Corresponding Author. The name, address, telephone and fax numbers, and e-mail address of the author responsible for reviewing the page proofs should be provided on the title page of the manuscript. Manuscripts should be sent to PROCEED- INGS OF THE NATIONAL ACADEMY OF SCIENCES, 2101 Consti- tution Avenue, N.W., Washington, DC 20418 USA, or by courier or express mail to 1055 Thomas Jefferson Street, N.W., Suite 2013, Washington, DC 20007 USA. Phone: (202) 334- 2672. Fax: (202) 334-2739. E-mail: [email protected].

Publication Charges. Page charges: PNAS depends, in part, on the payment of page charges for its operation. Payment of the page charge of $70 per printed page is expected for all authors who have funds available for that purpose. Requests for waiver of page charges should be submitted to the Editor- in-Chief. Articles are accepted or rejected only on the basis of merit.

Color illustration charges: Author(s) must pay the additional cost of color illustrations. The cost is $600 for the first color figure and $300 for each additional color figure. A single figure is defined as original art that can be processed as a unit and printed on one page without intervening type. A quotation will be sent to the corresponding author, and written approval must be received before the color illustrations are processed. Each sub- sequent replacement or deletion of a color figure will cost $300.

Manuscript Preparation

Disks. To expedite publication, all manuscripts must be accompanied by a computer disk. The version on the disk must match the hard copy. Guidelines for papers submitted in TeX or LaTeX may be obtained.

Supplementary Material. All Supplementary Material should be saved, preferably in HTML, on a separate floppy disk, marked clearly as "Supplementary Material" with the title and corresponding author's name. Five clearly marked paper copies of the Supplementary Material should also be supplied, similarly marked. File sizes should be as small as possible. Include a brief description of the contents of each file and the types of files submitted. Please refer to the Supple- mentary Material in the printed version of your manuscript at an appropriate point in the text or figure/table legend.

Text can be supplied as a file in any format, but for graphics and data, the following are recommended:

.txt, Plain ASCII text*

.pdf, PostScript file

.doc, MS Word 6 document

.ps, PostScript file

.mov, Quick Time

.gif, graphical image file*

.htm, HTML*

.jpg, JPEG image file*

.wav, Sound

.xls, MS Excel spreadsheet

Manuscript Length. PNAS uses a two-column format av- eraging 60 characters, including spaces, per line. The maximum

*These files can be viewed directly on standard web browsers.

Checklist for Submission:

Submit the following with the cover letter: * Five complete copies (six for Track II submissions) of the

manuscript in final form, printed double-spaced, pages num- bered, with one set of figures for the printer, four sets of high- quality figures, and one photocopied set of figures. All illustrations should be submitted at final size. If this is not feasible, indicate the desired reduction and, if possible, include one photocopy of figures at final size. Return of figures cannot be guaranteed.

* One computer disk of the final version of the manuscript. Identify the platform, program, first author, date, and file name on the disk label.

* The character count breakdown of the manuscript. Submit the completed Worksheet for Sizing Papers.

* The completed Copyright Assignment Form. * The completed Documentation Report. * The classification of the paper. * References according to PNAS style.

length of a research article is six printed pages or 47,000 characters, including all text, spaces, and the number of characters displaced by figures, tables, and equations. The total number of characters equals:

The number of characters including spaces in the text (include all parts except tables), plus

The height in cm of each figure at desired printed size x 180 for a one-column figure or x 360 for a two-column figure, plus

The height in number of lines of each table x 60 for a one-column table or x 120 for a two-column table, plus

A 120-character allowance for the space above and below each single column of a figure, table, or equation, plus

An additional 60 characters for each one-column line of equation.

A table that has lines with more than 60 characters plus spaces or a figure that is wider than 8.5 cm takes up two columns in width.

If the word processing program character count excludes spaces, add the word count to the character count to obtain a character count that includes spaces.

Authors will be responsible for additional charges incurred due to shortening overlong papers in proof.

MANUSCRIPT FORMAT

Title Page. Include the following information on this page: Classification: Select a major (Physical, Biological, or Social

Sciences) and a minor category from the following. Dual

EXAMPLE (PROVIDE BREAKDOWN WITH MANUSCRIPT):

Character Material count

All text characters (including title page, abstract, legends, references) plus spaces 25,660

Fig. 1 (1-column, 16 cm high = 180 x 16) 2,880 Fig. 2 (1-column, 12 cm high = 180 x 12) 2,160 Fig. 3 (1-column, 21 cm high = 180 x 21) 3,780 Fig. 4 (1-column, 11 cm high = 180 x 11) 1,980 Fig. 5 (2-column, 17 cm high = 360 x 17) 6,120 Table 1 (2-column, 23 lines high = 120 x 23) 2,760 Equations [one 2-line and one 1-line eq., 1-col. (3 x 60)] 180 Space Allowance

4 single-column figures (4 x 120) 480 1 double-column figure (1 x 240) 240 1 double-column table (1 x 240) 240 2 single-column equations (2 x 120) 240

Total characters in paper (must not exceed 47,000) 46,720

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Page 7: Back Matter

xvi Information for Authors Proc. Natl. Acad. Sci. USA 96 (1999)

classifications are permitted between major categories and in exceptional cases, subject to Editorial Board approval, within a major category.

Physical Sciences: Applied Mathematics, Applied Physical Sciences, Astronomy, Chemistry, Computer Sciences, Engineer- ing, Geology, Geophysics, Mathematics, Physics, and Statistics.

Biological Sciences: Agricultural Sciences, Applied Biological Sciences, Biochemistry, Biophysics, Cell Biology, Developmental Biology, Ecology, Evolution, Genetics, Immunology, Medical Sciences, Microbiology, Neurobiology, Pharmacology, Physiol- ogy, Plant Biology, Population Biology, and Psychology.

Social Sciences: Anthropology, Economic Sciences, Psychol- ogy, Political Sciences, and Social Sciences.

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Proceedings of the National Academy of Sciences

Worksheet for Sizing Research Articles

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Proceedings of the National Academy of Sciences

Author names: Ms. No. (if known): _

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Please check, sign, and include this form with your manuscript.

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THE PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, USA (PNAS)

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CONFERENCES t

IL J?L3 __1< 1 PHILIPPE LAUDAT INSTITUT NATIONAL DE LA SANTE Aix-les-Boins (Savoy) - France - 1999 SCIENTIFIC COMMITTEE

ET DE LA RECHERCHE MEDICALE e Laurent ABEL (INSERM U.436, France), Jenefer M. BLACKWELL (University of Cambridge, UK), Jean-Laurent CASANOVA (INSERM U.429, France),

ala DESSEIN (INSERM U.399, France), Stefan H.E. KAUFMANN ~MxPlanck Institute for Infection Biology, Germany).

SCIENTIFIC COMMITTEE SCIENTIFIC COMMITTEE PRELIMINARY PROGRAMME SEN IF U CandeauxE The identification of host genes controlling the response to infectious agents Pierre MORMEDE (INSERM U.471, Bordeaux, France), John CRABBE )OHSU, Bent RUBIN )CNRS-ERS 1590, Toulouse, France), Balbino ALARCON (Univ. is a tremendous challenge. These genetic findings are expected to have

Portland, USA), Jean-Pierre LEPINE (Hopital Lariboisiere Fernand Widal, Paris, Aut. Madrid, Spain), Carsten GEISLER (Univ. Copenhagen, Denmark), Ada major implications for the control of infectious diseases. This conference will France), Klaus-Peter LESCH (University of Wuerzburg, Germany). KRUISBEEK (The Netherlands Cancer Institute, The Netherlands), Ed PALMER present the recent advances obtained in genetic susceptibility/resistance to PRELIMINARY PROGRAMME (Basel Institute Immunology, Switzerland). parasites, bacteria, viruses and prions. The different methods and strategies The analysis of the co-transmission of some aspects of personality and various PRELIMINARY PROGRAMME that can be used in humans and animals to identify genetic factors components of psychopathological syndromes allows the redefinition of clini- The conference deals with the latest progress in T cell receptor and CD3 bio- predisposing to infectious diseases will be discussed. This multidisciplinary cal entities and the tracking of the relationships between temperamental varia- synthesis, assembly, membrane expression and function. Topics will include conference will bring together scientists from various fields such as human tions in the general population and pathologies of behaviour. This meeting will TCR crystalstructures, TCR/CD3 complex stoichiometry, TCR/CD3 assembly and animal genetics, immunology, microbiology, epidemiology, paediatrics be organised around three clinical entities related to the principal dimensions in CD3 deficient mice or human immunodeficiency patients and newchape- and infectious diseases medicine. of personality: attention deficit with hyperactivity disorders (ADHD), mood rones in TCR/CD3 assembly. TCR/CD3 structure/function relationship SPEAKERS disorders (anxiety / depression) and substance abuse. The conference covers during thymocyte differentiation, and the role of TCRo, 3, 7, and B chains or L. Abel (France), J. M.Blackwell (UK), M. Brahic (France), J.-L. Casanova a research area of psychopathology and genetic psychiatry in rapid develop- CD37, g, e, C chains in positive and negative selection will be discussed. The (France), M. Dean (USA.), A. Dessein (France), S.Foote (Australia), P. Gros ment. It will bring together scientists from different fields, differential psycholo- changes in TCR/CD3 complex composition and stoichiometry during the (Canada), A. Hill (UK.), S. Holland (USA), R. Horstmann (Germany), gists and psychiatrists, behaviour geneticists, neurobiologists, to draw bridges thymocyte maturation process [CD3vy ->TCR7g/CD3 -> pTCR/CD3 -> S. H.E. Kaufmann (Germany), F. Lantier (France ), A. McMichael (UK), between physiology and pathology, and between clinical and experimental TCRox/CD3] will be considered as well. R. North (USA.), G. Orth (France), E. Schurr (Canda), T. Seemayer (USA), approaches. SPEAKERS A. Sher (USA), T. Shirakawa (UK), E. Skamene (Canada), M. Troye- SPEAKERS B. Alarcon (Spain); B. Arnold (Germany); M. Bonneville (France); Blomberg (Sweden), D. Weatherall (UK), J. Weissenbach (France), A. Armorio (Spain), R.H Belmaker (Israel), J. Biederman (USA), S. Brown (UK), H.J. Fehling (Switzerland); C. Geisler (Denmark); T Gobel (Switzerland); C. Weissmann (Switzerland). F. Chaouloff (France), C.R. Cloninger (USA), A. Cools (The Netherlands), W. Havran (USA); D. Kappes (USA); K. Karialainen (Switzerland); J. Crabbe (USA), T. Eley (UK), J. Flint (UK), M. Gill (Ireland), P. Gorwood A. Kruisbeek (The Netherlands); A. Lanzavecchia (Switzerland); B. Malissen Conferences Philippe Laudat / INSERM (France), R. Grailhe (France), B.C. Jones (USA/France), M.O. Krebs (France), (France); M. Owen (UK); E. Palmer (Switzerland); P. Pereira (France); Stephane MONTSERRAT (DISC) M. Leboyer (France), J.-P. lepine (France), K.-P. Lesch (Germany), F. Levy R. Perlmutter (USA); H. Ploegh (USA); J.R.Regueiro (Spain); B. Rubin 101, rue de Tolbiac - 75654 Paris Cedex 13 - France (Australia), M.-P. Moisan (France), P. Mormdde (France), T. Sagvolden (France); C. Terhorst (USA); L. Teyton (USA/France); M.-L. Toribio (Spain); Tel. : (33) 01 44 23 60 89 - Fox: (33) 01 44 23 60 69 (Norway), J. Stevenson (UK). A. Troutmann (France); A.-M. Verhulst (France); D.L. Wiest (USA). [email protected] - [email protected] - www.inserm.fr

9~~~ ~ ~ ~ ~ Is

VISITING POST DOC | j

Mutator Transposon Evolution/Genomics

Pursue independent research involving maize transposon Mutator. Some aspects of Mu functional genomics and/or evolution of MuDR in grasses will be explored. Specific project by R t a negotiation with PI. Supervise technicians as Readthe award-winning science required. Prepare research results for publication policy journal, published by the and annual reports. Participate in preparation of National Academy of Sciences proposals including fellowships. Some work in and the greenhouse and field.

Cecil and Ida Green Center at Qualifications: Ph.D. in genetic biology. Strong the University of Texas at interest in evolution as a discipline. Experience Dallas. with routine and experimental PCR procedures. Experience with one or more grass species You'll find expert opinions on desirable. Annual salary from $26K to $41K, depending on experience. Appointment is for one the environment, health, R&D, year with possibility of renewal contingent upon defense, education, and many finding. Send letter, vita and 3 letters of reference more topics. with phone and/or email addresses by 5/13/99 to Mike Freeling, Dept. of Plant and Microbial Biology, U.C. Berkeley, Berkeley, CA 94720 or to [email protected]. i Inij~r:ian

U. C. Berkeley is an AA/EOE. l * l

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01,1- 4 NATiONAL AcADEMY OF SCIENCES COLLOQUIA

Bound Reprints

N1) is Now Available

In 1991, the National Academy of Sciences (NAS) inaugurated a series of scientific colloquia, several of which are held each year under the auspices of the NAS Council Committee on Scientific Programs. These colloquia address scientific topics of broad and topical interest that cut across two or more traditional disciplines. Typically two days long, these colloquia are international in scope and bring together leading scientists in their field.

Papers presented at these colloquia are published in the Proceedings of the National Academy of Sciences (PNAS) and are available online (www.pnas.org). Because they have generated much interest, these papers now will be available in the form of collected bound reprints which may be ordered through the National Academy Press.

Currently available are:

Carbon Dioxide and Climate Change ($11.00) Held November 13-15, 1995 (Irvine, CA)

Computational Biomolecular Science ($16.00) Held September 12-13, 1997 (Irvine, CA)

Earthquake Prediction ($16.00) Held February 10-11, 1995 (Irvine, CA)

Elliptic Curves and Modular Forms ($7.00) Held March 15-17, 1996 (Washington, DC)

Genetic Engineering of Viruses and Viral Vectors ($21.00) Held June 9-11, 1996 (Irvine, CA)

Genetics and the Origin of Species ($8.00) Held January 31-February 1, 1997 (Irvine, CA)

Neuroimaging of Human Brain Function ($17.00) Held May 29-31, 1997 (Irvine, CA)

Protecting Our Food Supply: The Value of Plant Genome Initiatives ($13.00) Held May 29-31, 1997 (Irvine, CA)

Science, Technology, and the Economy ($12.00) Held November 20-22, 1995 (Irvine, CA)

The Age of the Universe, Dark Matter, and Structure Formation ($13.00) Held March 21-23, 1997 (Irvine, CA)

Papers from future colloquia will be available for purchase after they appear in PNAS.

Shipping and Handling Charges In the U.S. and Canada please add $4.00 for the first reprint ordered and $0.50 for each additional reprint.

Ordering Information Telephone orders will bDe accepted only when charged to VISA, Mastercard, or American Express accounts.

To order call toll-free 1-800-624-6242

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S~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~' " tudent.s, and Postdoc&- . Rx q>,f:R2''*.q

Subscribe to C PNAS Online \'\ for 1999 at $2O/yr. . .

and get the ( Albert t-sbirt free! ;

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ILARJZOURNAL National Research Council INSTITUTE FOR LABORATORY ANIMAL RESEARCH

ILAR Journal is the quarterly, peer-reviewed publication of the Institute for

Laboratory Animal Research (ILAR), which is a unit of the National Research

Council, National Academy of Sciences. ILAR Journal provides thoughtful and

timely information for all those who use, care for, and oversee the use of labora-

tory animals. The audience of ILARJournal includes more than 3,500 investigators

in biomedical and related research, institutional officials for research, veterinarians,

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and receive a subscription to ILARJournal,

Call 202-334-2590, or click on www2.nas.edulilarhome

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I$ National Academy of Sciences t2* ;~2 2101 Constitution Avenue, NW

X C OFWashington, DC 20418 b8wED

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