Back MatterSource: Proceedings of the National Academy of Sciences of the United States of America,Vol. 69, No. 4 (Apr., 1972), pp. 1065-1068Published by: National Academy of SciencesStable URL: http://www.jstor.org/stable/61766 .

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Selected New and Recent Titles from

NATIONAL ACADEMY OF SCIENCES NATIONAL ACADEMY OF ENGINEERING

NATIONAL RESEARCH COUNCIL

The Atmospheric Sciences and Man's Needs: Priorities for the Future, Committee on Atmospheric Sciences

ISBN 0-309-01912-5; 1971, viii + 88 pp., paper, $3.95 From among the many possible applications of

the atmospheric sciences, those that can contribute most to the solution of pressing problems in the next 5 to 10 years are delineated in this report, which also proposes an ordering of research priorities responsive to current needs.

Biochronometry, Division of Biology and Agriculture ISBN 0-309-01866-8; 1971, x + 662 pp., cloth, $15.50

The papers and discussions in this newly published record of a symposium on biochronometry report on a wide range of research in this field. Included are sections on systems and models, photo- periodic time measurements, photoreception in rhythms and photoperiodism, circannual rhythms and photo- periodic control, neural and endocrine controls, and cellular and biomedical mechanisms.

The Life Sciences, Committee on Science and Public Policy

ISBN 0-309-01770-X; 1970, xix + 525 pp., paper, $10.50 The most recent in a series of well-known

surveys of major fields of science, this report presents and analyzes data provided by more than 12,000 senior investigators and almost 1,300 college and university departments in the biological, agricultural, and medical sciences. It describes many characteristics of life scientists, presents a detailed description of academic endeavor in the field, considers problems in the handling of biological information, and discusses the unique role of the digital computer in the life sciences.

Marine Chemistry, Ocean Affairs Board ISBN-0-309-01928-1; 1971, x + 62 pp., paper, $2.50

This report describes the field of marine chem- istry, the activities of marine chemists, and the nature of the principal problems in the field. Not designed for professionals in the field, this report is directed toward those in neighboring scientific fields who may be interested in knowing more about the work of marine chemists.

Priorities for Space Research 1970-1980, Space Science Board

ISBN 0-309-01872-1; 1971, xii + 148 pp., paper, $4.50 Those concerned with space science and

applications programs will find useful information in this report, which discusses the objectives, estimated cost, and relative priorities of various missions in planetary and lunar exploration, astronomy, gravita- tional physics, earth environmental sciences, and the life sciences. The report deals mainly with proposed new starts, emphasizing the need for balancing large complex missions with smaller missions of high scientific priority.

Source Material for Radiochemistry, Committee on Nuclear Science

ISBN 0-309-01867; 1971, 117 pp., paper, $2.75 If you are working or studying in the field of

radiochemistry, you may find many valuable references in the new edition of this guide. It contains references to literature on basic nuclear physics and chemistry, radiochemical separation procedures and counting techniques, radiochemical applications, the design of radiochemical laboratories, and radiological safety.

NATIONAL ACADEMY OF SCIENCES Printing and Publishing Office 2101 Constitution Avenue Washington, D.C. 20418

Complete Catalog Available Upon Request

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AUTHOR INDEX, APRIL 1972

Aaronson, S. A. 980 Adam, A. 851 Andersen, A. E. 863 Anderson, W. F. 983 Antonini, E. 868 Aris, R. 777 Armstrong, M. Y. K. 877 Athwal, R. S. 912 Babalola, 0. 946 Bauer, H. 888 Berger, F. M. 855 Bonaventura, C. 868 Bonaventura, J. 868 Bonkowsky, H. L. 1008 Borek, C. 956 Bosch, V. 970 Bossenmaier, I. 1008 Braun, V. 970 Brunori, M. 868 Brutlag, D. 965 Bunting, J. R. 795 Cancedda, R. 946 Cantor, C. R. 837 Capaldi, R. A. 930 Cardinal, R. 1008 Cartas, M. 791 Cary, P. 1008 Cathou, R. E. 795 Chedid, L. 855 Christman, D. 988 Ciorbaru, R. 851 Cohen, S. S. 1048 Coleman, J. E. 859 Collins, A. 1008 Commerford, S. L. 842 Crawford, E. J. 988 Davidson, F. D. 784 Davidson, R. L. 951 DeLange, R. J. 882 Diegelmann, R. F. 892 Doherty, J. 1008 Dressler, D. 998 Drickamer, H. G. 933 Dulbecco, R. 921 Erfurth, S. C. 938 Faraggi, M. 902 Frank, C. W. 933 Friedkin, M. 988 Fritz, I. B. 1003 Fuoss, R. M. 829 Ganem, D. 897 Gatti, R. A. 980 Gelboin, H. V. 824 Gest, H. 916 Gilbert, J. M. 983 Gilbert, L. I. 812 Gilden, R. V. 1021 Good, R. A. 980, 1026 Gorell, T. A. 812

Green, M. 791,1036 Gross, S. K. 872 Guroff, G. 863 Gustafson, R. H. 855 Hall, R. L. 786 Halperin, M. L. 1003 Hamilton, L. D. 842 Handler, J. S. 805 Hartley, J. W. 1033 Haverland, W. J. 809 Hehlmann, R. 1007 Henning, U. 925 Hochberg, A. A. 800 Hofschneider, P. H. 888 Hooper, J. A. 882 Huebner, R. J. 1009 Hughes, R. C. 942 Hunt, R. K. 780 Jacobson, M. 780 Jeanloz, R. W. 942 Jefferson, L. S. 816 Kabat, E. A. 960 Katchalsky, A. 993 Keller, K. H. 777 Kersey, J. H. 980 Kimber, G. 912 Kinoshita, N. 824 Kiser, E. J. 938 Klein G. 1056 Koehler, J. O. 816 Komiyama, J. 829 Konigsberg, W. H. 877 Konings, R. N. H. 888 Kornberg, A. 965 Kufe, D. 1007 Kung, H.-F. 925 Lardy, H. A. 800 Lederer, E. 851 Lien, S. 916 Loach, P. A. 786 Lowy, D. R. 1033 Luzzatto, L. 946 Magazin, M. 998 Marrs, B. 916 Merrick, W. C. 983 Miller, J. H. 897 Miller, S. L. 809 Morahan, P. S. 842 Morgan, H. E. 816 Munson, A. E. 842 Musson, R.A. 877 Neumann, E. 993 Oen, H. 837 Orloff, J. 805 Oroszlan, S. 1021 Pairault, J. 847 Paoletti, C. 847 Parant, F. 855

Parant, M. 855 Pauling, L. 1008 Peach, M. J. 834 Pecht, I. 902 Pellegrini, M. 837 Peterkofsky, B. 892 Peticolas, W. L. 938 Petit, J.-F. 851 Platt, T. 897 Prichard, P. M. 983 Regelson, W. 842 Richards, F. F. 877 Riou, G. 847 Robbins, P. W. 872 Robinson, A. B. 1008 Robinson, B. H. 1003 Roblin, R. 921 Rosenstein, R. W. 877 Rowe, W. P. 1033 Sakiyama, H. 872 Sanford, B. 942 Schekman, R. 965 Schiller, P. W. 975 Shafritz, D. A. 983 Shubik, P. 1052 Siddall, J. B. 812 Siegert, W. 888 Simon, L. D. 907 Slichter, C. P. 933 Smith, E. L. 882 Spiegelman, S. 1007 Stahl, C. L. 916 Stoff, J. S. 805 Stratman, F. W. 800 Taylor, J. S. 859 Teich, N. 1033 Temin, H. M. 1016 Teranishi, R. 1008 Todaro, G. J. 980, 1009 Totten, D. K., Jr. 784 Trudinger, N. S. 821 Tschudy, D. P. 1008 Vanderkooi, G. 930 von Bekesy, G. 885 Walter, G. 921 Watson, C. J. 1008 Weber, K. 897 Werner, T. C. 795 Wickner, W. 965 Wolf, A. P. 988 Wolfson, J. 998 Wolman, Y. 809 Wu, T. T. 960 Wyckoff, R. W. G. 784 Wyman, J. 868 Zahlten, R. N. 800 Zubrod, C. G. 1042

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Selected New and Recent Titles from NATIONAL ACADEMY OF SCIENCES NATIONAL ACADEMY OF ENGINEERING NATIONAL RESEARCH COUNCIL

Asbestos: The Need for and Feasibility of Air Pollution Controls, Committee on Biologic Effects of Atmospheric Pollutants

ISBN 0-309-01927-3; 1971, vii + 40 pp., paper, $1.75 This monograph discusses the pathogenicity of

asbestos in man and animals, human nonoccupational exposure to asbestos, and health risks associated with various degrees and types of exposure. It also identifies sources of environmental contamination by asbestos and indicates high-priority areas where research is needed.

An Assessment of Industrial Activity in the Field of Biomedical Engineering, Committee on the Interplay of Engineering with Biology and Medicine

ISBN 0-309-01925-7; 1971, xvi + 146 pp., paper, $5.25 Current attitudes and activities in the biomedical

engineering industry are analyzed in this report, which also offers a profile of the industry, identifies major areas that have an effect on industrial contributions to the health care system, and recommends action to meet current and future needs in health care.

Evaluating the Safety of Food Chemicals, Food Protec- tion Committee

ISBN 0-309-01859-5; 1970, v + 55 pp., paper, $2.50 This report directs attention to recently

proposed or adopted procedures for evaluation of the safety of food chemicals and considers the new methods against a background of experience with conventional procedures.

Fluorides, Committee on Biologic Effects of Atmos- pheric Pollutants

ISBN 0-309-01922-2; 1971, xi + 295 pp., paper, $6.50 For those concerned with the biologic effects of

atmospheric pollutants, this volume evaluates the

world literature on fluorides and summarizes the best scientific knowledge available on their biologic effects. Topics discussed include environmental sources and forms of fluorides and their relative hazards to plants, animals, and humans, with particular emphasis on the susceptibility of special population groups.

Jamaica Bay and Kennedy Airport: A Multidisciplinary Environmental Study, Environmental Studies Board

ISBN 0-309-01874-4; 1971, 178 pp. in 2 volumes + 13 foldout 3-color maps, paper, $8.95 per set

This report identifies and evaluates the effects of various plans for expansion of New York's Kennedy Airport on the physical environment and on human ecology in the Jamaica Bay area, suggests alternative courses of action, and examines their implications.

Immunoglobulins: Biologic Aspects and Clinical Uses, Ed. by Ezio Merler, Division of Medical Sciences

ISBN 0-309-01850-1; 1971, xii + 404 pp., illus., cloth, $9.50

The papers presented in this volume review the fundamental, technological, and clinical aspects of immunoglobulins and suggest lines of investigation that may further increase their value in preventing and alleviating human disease.

Reference Methods for the Microbiological Examination of Foods, Food Protection Committee

ISBN 0-309-01863-3; 1971, 40 pp., paper, $2.25 In an effort to simplify laboratory practice and

minimize variability of results, this report suggests reference methods for establishing microbiological criteria for classes of foods susceptible to micro- biological contamination.

NATIONAL ACADEMY OF SCIENCES Printing and Publishing Office 2101 Constitution Avenue Washington, D.C. 20418

Complete Catalog Available Upon Request

1067

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Contents (Continued from inside back cover)

Aryl hydrocarbon hydroxylase and polycyclic hydrocarbon tumorigenesis: effect of the enzyme inhibitor 7,8-benzoflavone on tumorigenesis and macromolecule binding (benzo(a)pyrene/7,12-dimethylbenz(a)- anthracene/DNA, RNA, and protein binding/mouse skin). . Nadao Kinoshita and Harry V. Gelboin 824-828

Biological study of a nontoxic, water-soluble immunoadjuvant from mycobacterial cell walls (glycopep- tide/agglutinins/precipitins/nonspecific immunity)............ ................L. Chedid, M. Parant, F. Parant, R. H. Gustafson, and F. M. Berger 855-858

Construction of the three-dimensional model of the polypeptide backbone of the variable region of kappa immunoglobulin light chains (Bence Jones proteins/tripeptides/(0,g/) angles) ..... ......................... ... . ... Elvin A. Kabat and Tai Te Wu 960-964

Susceptibility of cells from patients with primary immunodeficiency diseases to transformation by simian virus 40 (skin fibroblasts/T antigen/immune surveillance) .........

. . John H. Kersey, Richard A. Gatti, Robert A. Good, Stuart A. Aaronson, and George J. Todaro 980-982 Contact regions for dinitrophenyl and menadione haptens in an immunoglobulin binding more than one

antigen (myeloma protein/combining site/sulfhydryl group/antibody heterogeneity). .. .. Robert W. Rosenstein, Robert A. Musson, Martine Y. K. Armstrong, W. H. Konigsberg, and Frank F. Richards 877-881

The shape of immunoglobulin G molecules in solution (rabbit antiserum/hapten/fluorescein/singlet- singlet energy transfer/conformation) . . . . T. C. Werner, James R. Bunting, and Renata E. Cathou 795-799

MEDICAL Repression of the overproduction of porphyrin precursors in acute intermittent porphyria by SCIENCES intravenous infusions of hematin (Correction) . .... . .. . .. .. .... .

H. L. Bonkowsky, D. P. Tschudy, A. Collins, J. Doherty, I. Bossenmaier, R. Cardinal, and C. J. Watson 1008 Quantitative analysis of urine vapor and breath by gas-liquid partition chromatography (Correction)

. . ......... . .... . .L. Pauling, A. B. Robinson, R. Teranishi, and P. Cary 1008 MICROBIOLOGY RNA in human leukemic cells related to the RNA of a mouse leukemia virus (Correction).......

. .......... ....... ... . .. .. jR. Hehlmann, D. Kufe, and S. Spiegelman 1007 Antiviral activity and side effects of polyriboinosinic-cytidylic acid complexes as affected by molecular

size (synthetic polynucleotide/interferon/antitumor agent/drug metabolism) ....... . . . ... . .P S. S. Morahan, A. E. Munson, W. Regelson, S. L. Commerford, and L. D. Hamilton 842-846

Infection of Escherichia coli by T2 and T4 bacteriophages as seen in the electron microscope: T4 head morphogenesis (capsids/plasma membrane/tau particles/phage heads/DNA ) . .. .Lee D. Simon 907-911

PATHOLOGY Neoplastic transformation in vitro of a clone of adult liver epithelial cells into differentiated hepatoma- like cells under conditions of nutritional stress (contact inhibition/agglutination/intercellular communi- cation/karyotype/cytodifferentiation) ................... ... Carmia Borek 956-959

PHYSIOLOGY Asymmetries generated by diffusion and reaction, and their bearing on active transport through mem- branes (model/theoretical/Michaelis-Menten) ........ .... . R. Aris and K. H. Keller 777-779

Stimulation of release of adrenal catecholamine by adenosine 3':5'-cyclic monophosphate and theo- phylline in the absence of extracellular Ca2+ (methylxanthine/cat/dibutyryl-cyclic AMP) . .. . . . .. . . . . . . . . .. . . . . . . .. . . . .. . .. . .. . . Michael J. Peach 834-836

PSYCHOLOGY Enduring behavioral changes in rats with experimental phenylketonuria (phenylalanine to tyrosine ratio/ p-chlorophenylalanine/disease model/learning ability/brain structure) ........

........................... Arnold E. Andersen and Gordon Guroff 863-867 Lines that do not increase their width under a magnifying glass (vision/Mach bands/retinal receptors/

luminance/optical illusion) . ........ ............ . . Georg von Bekesy 855-887

Corrections

MEDICAL Repression of the overproduction of porphyrin precursors in acute intermittent porphyria by intrave- SCIENCES nous infusions of hematin ...

H. L. Bonkowsky, D P. Tschudy, A. Collins, J. Doherty, I. Bossenmaier, R. Cardinal, and C. J. Watson 1008 Quantitative analysis of urine vapor and breath by gas-liquid partition chromatography ...

.................... L. Pauling, A. B. Robinson, R. Teranishi, and P. Cary 1008

MICROBIOLOGY RNA in human leukemic cells related to the RNA of a mouse leukemia virus ..... ........ .................. .... ... R. Hehlmann, D. Kufe, and S. Spiegelman 1007

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Contents (Continued from outside back cover)

Limiting availability of binding sites for dehydrogenases on the cell membrane of Escherichia coli (acyl- CoA /glycerophosphate/lactate/succinate/respiration) ... . . .Hsiang-Fu Kng and Ulf Henning 925-929

Biochemical physiology of a respiration-deficient mutant of the photosynthetic bacterium Rhodopseudo- monas capsulata (bacteriochlorophyll/anaerobic growth/dark aerobic growth/photophosphorylation sys- tem). ............... Barry Marrs, Carol L. Stahl, Stephen Lien, and Howard Gest 916-920

Long-lived conformation changes induced by electric impulses in biopolymers [memory recording/meta- stability/biopolyelectrolytes/poly(A )/poly(U) ....... Eberhard Neumann and Aharon Katchalsky 993-997

Circular oligomers in mitochondrial DNA of human and beef nonmalignant thyroid glands (nonmalig- nant/dimers/electron microscopy) ....... . Claude Paoletti, Guy Riou, and Jacques Pairault 847-850

Electron transfer to ferricytochrome c: reaction with hydrated electrons and conformational transitions involved (horse heart cytochrome c/pulse radiolysis/Pseudomonas cytochrome c/protein relaxation/dif- ference spectra). ...................... ..Israel Pecht and Moshe Faraggi 902-906

Covalent attachment of a peptidyl-transfer RNA analog to the 50S subunit of Escherichia coli ribo- somes (protein synthesis/acrylamide gel/ax-bromoamide/affinity label) ........ .................... . . Maria Pellegrini, Helen Oen, and Charles R. Cantor 837-841

Translational restarts: AUG reinitiation of a lac repressor fragment (protein biosynthesis/antibody/gel electrophoresis/amino-acid sequence/E. coli) .. . . ...................

................. ..Terry Platt, Klaus Weber, Don Ganem, and Jeffrey H. Miller 897-901 Study of adrenocorticotropic hormone conformation by evaluation of intramolecular resonance energy

transfer in Nf-dansyllysine2l-ACTH-(1-24)-tetrakosipeptide (fluorescence spectra/Forster parameters/ side-chain flexibility/intramolecular distances ) .. . ...... . Peter W. Schiller 975-979

Separation of reticulocyte initiation factor M2 activity into two components (protein biosynthesis/hemo- globin/rabbit/Sephadex/liver factors) .............. David A. Shafritz, Philip M. Prichard, Jeffrey M. Gilbert, William C. Merrick, and W. French Anderson 983-987

Translation of avian myeloblastosis virus RNA in a cell-free lysate of Escherichia coli (in vitro protein synthesis/gel electrophoresis/radioimmune assay/ferritin) .......... .. ... . . .. . .. W. Siegert, R. N. H. Konings, H. Bauer, and P. H. Hofschneider 888-891

The effect of aldosterone on the accumulation of adenosine 3': 5'-cyclic monophosphate in toad bladder epithelial cells in response to vasopressin and theophylline (steroid permissive effect/permeability changes/cAMP degradation) . ... . ... .Jeffrey S. Stoff, Joseph S. Handler, and Jack Orloff 805-808

Nitrogen ligands at the active site of alkaline phosphatase (Zn/Cu/E. coli/electron spin resonance).. ...........................June S. Taylor and Joseph E. Coleman 859-862

Amino-acid composition of heated oyster shells (Pliocene/fossils) ......... .............. David K. Totten, Jr., Franklin D. Davidson, and Ralph W. G. Wyckoff 784-785

RNA synthesis initiates in vitro conversion of M13 DNA to its replicative form (+X174 DNA/DNA initiation/DNA replication/rifampicin) .............. ............ William Wickner, Douglas Brutlag, Randy Schekman, and Arthur Kornberg 965-969

Glucagon-stimulated phosphorylation of mitochondrial and lysosomal membranes of rat liver in vivo (hormone/inorganic phosphate/phospholipids) ............. ........ R.. Rainer N. Zahlten, Abraham A. liochberg, F. W. Stratman, and Henry A. Lardy 800-804

CELL BIOLOGY Inhibition of collagen secretion from bone and cultured fibroblasts by microtubular disruptive drugs (synthesis/hydroxylation/procollagen/colchicine/vinblastine/cytochalasin B) .. . .. .. . .. ........................ Robert F. Diegelmann and Beverly Peterkofsky 892-896

Determination of the backbone structure of nucleic acids and nucleic acid oligomers by laser Raman scattering (calf-thymus DNA /yeast transfer RNA /guanylyl-3' :5'-cytidine) ...... .................. Stephen C. Erfurth, Ernest J. Kiser, and Warner L. Peticolas 938-941

Development and stability of positional information in Xenopus retinal ganglion cells (neuronal speci- ficity/retinotectal connections/eye transplantation) ...... ..R. K. Hunt and Marcus Jacobson 780-783

Effect of insulin on protein synthesis in skeletal muscle of an isolated perfused preparation of rat hemi- corpus (psoas muscle/gastrocnemius muscle/ribosomal subunits/fatty acid/fasting) ..... . .. ....... .. . . . . . . ..... L. S. Jefferson, J. O. Koehler, and H. E. Morgan 816-820

Glycolipid synthesis in normal and virus-transformed hamster cell lines (hamster sarcoma virus/polyoma virus/saturation density/Forssman antigen) ............. .................. Hisako Sakiyama, Sonja K. Gross, and Phillips W. Robbins 872-876

Protein synthesis in simian virus 40-infected monkey cells (structural and nonstructural proteins/gel elec- trophoresis/polyoma) ........... .Gernot Walter, Richard Roblin, and Renato Dulbecco 921-924

GENETICS Regulation of melanin synthesis in mammalian cells: effect of gene dosage on the expression of differentia- tion (somatic hybridization/hamster/dihydroxyphenylalanine oxidase/mouse fibroblasts/clones) . .. ................................... . . . Richard L. Davidson 951-955

A reassessment of the course of evolution of wheat (speciation/synapsis/hybrids/polyploid/chromosomes) .............................. Gordon Kimber and R. S. Athwal 912-915

IMMUNOLOGY Isolation and properties of a macromolecular, water-soluble, immunoadjuvant fraction from the cell wall of Mycobacteriumz smegmatis (Sephadex chromatography/cell-wall oligomer/wax D/Freund's adju- vant/guinea pig). ..... ..Arlette Adam, Rita Ciorbaru, Jean-Franfois Petit, and Edgar Lederer 851-854

(Continued on page 1068)

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Contents Vol. 69, No. 4 April 1972

INFORMATION TO CONTRIBUTORS. . . . .. . . .. .. . .. .. . .. . .. . . . .. . . .. .. . . . .

National Academy of Sciences Autumn Meeting (October 1971)

SYMPOSIUM: New EVIDENC;E AS THE BASIS FOR INCREASED EFFORTS IN CANCE:R RRESEARCH

The viral oncogene hypothesis: new evidence .. .. ...George J. Todaro and Robert J. Huebner Oin the development of programs in cancer research .............. Seymour S. Cohen (Group-specific antigens of R.NA tumor viruses as markers for subinfectious expression of the RNA virus

genomie .. . . . . . . . ............. Raymond V. Gilden and Stephen Oroszlan Relations between immunity and malignancy . .... . . . ..... ..Robert A. Good Molecular basis for the attack on cancer .................. . . Maurice Green

lIerpesviruses and oncogenesis. . . . . . . .............. . George Klein Sonme implications of the activation of murine leukemia virus by halogenated pyrimidines ...

............Wl. Wallace P. Rowe, Douglas R. Lowy, Natalie Teich, and Janet W. Hartley CurreInt status of chemical carcinogenesis ................... Philippe Shubik The RNA tumor viruses--background and foreground ... .... . . . . Howard M. Temin C(hemnical control of cancer .. . .. .. . . ........ .. C. Gordon Zubrod

Physical Sciences

(CI'm:MiST,rY Optical versus thermal transitions in solids at high pressure (electrons/excitations/theoretical). . ................I.... ... H. G. Drickamer, C. W. Frank, and C. P. Slichter

(Conductance in water-poly(vinyl alcohol) mixtures (viscosity/diffusion-controlled reactions/polymer solu- tions) ................. . Jiro Komiyama and Raymond M. Fuoss

The question of the primary electron acceptor in bacterial photosynthesis (Rhodospirillum rubrum/ photoreceptor/iron-depleted particles/quantLum yield/chromatophores) . . . P. A. Loach and R. L. Hall

Nonprotein amino acids from spark discharges and their comparison with the Murchison meteorite amino acids (gas chromatography-mass spectrometry/prebiotic synthesis/amino-acid analyzer) .. ................. Yecheskel Wolman, William J. Haverland, and Stanley L. Miller

MATHEMATICS A new proof of the interior gradient bound for the minimal surface equation in n dimensions ... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Neil S. Trudinger

Biological Sciences

BIOCHEMISTRY Genetic variants of glucose 6-phosphate dehydrogenase from human erythrocytes: unique properties of the A- variant isolated from "deficient" cells (protein structure/sulfhydryl groups/enzyme inactivation/ biochemical genetics) ......... .. Olaniyi Babalola, Ranieri Cancedda, and Lucio Luzzatto

Repetitive sequences in the murein-lipoprotein of the cell wall of Escherichia coli (covalent lipid/peptido- glycan/mucopcptide) . ..... . . . . . .. ... . . . V. Braun and V. Bosch

Carbon monoxide binding by hemoglobin and myoglobin under photodissociating conditions (heme proteins/ligand binding/protein photochemistry) ..)....................

. .Maurizio Brunori, Joseph Bonaventura, Celia Bonaventura, Eraldo Antonini, and Jeffries Wyman The low polarity of many membrane proteins (soluble proteins/polar amino acids/hydrophobicity/polarity

index) ...................... .Roderick A. Capaldi and Garret Vanderkooi l)etection of DNA synthesis in intact organisms with positron-emitting [methyl-"C] thymidine (cyclo-

tron/short-lived isotopes/liver/spleen/mice) ......... ........... David Christman, Elizabeth J. Crawford, Morris Friedkin, and Alfred P. Wolf

Complete amino-acid sequence of calf-thymus histone III (acetyllysine/methyllysine/acetylation/methyla- tion). ............ . . .Robert J. DeLange, John A. Hooper, and Emil L. Smith

Initiation and reinitiation of DNA synthesis during replication of bacteriophage T7 (E. coli/electron microscopy of DNA/origin of replication/direction of replication) ...... ..................... David Dressler, John Wolfson, and Marilyn Magazin

Binding-proteins for an ecdysone metabolite in the crustacean hepatopancreas (molting hormone/steroid/ sucrose gradient centrifugation) ... . . homas A. Gorell, Lawrence I. Gilbert, and John B. Siddall

The genome of R1NA tumor viruses contains polyadenylic acid sequences (murine sarcoma virus/avian mycloblastosis virus/70S RNA). .. .............. Maurice Green and Mlaria Cartas

Effects of palmitoyl CoA on citrate and malate transport by rat liver mitochondria (tricarboxylate trans- port system/fatty acid synthesis/surface molecules/metabolic regulation) . .......... ....................... M. L. Halperin, B. H. Robinson, and I. B. Fritz

Regeneration of the surface glycoproteins of a transplantable mouse tumor cell after treatment with neuraminidase (sialic acid/cytotoxic factor) .... . C. . . Hughes, B. Sanford, and R. W. Jeanloz

i-iv

1009-1015 1048-1051

1021-1025 1026-1032 1036-1041 1056-1064

1033-1035 1052-1055 1016-1020 1042-1047

933-937

829-833

786-790

809-811

821-823

946-950

970-974

868-871

930-932

988-992

882-884

998-1002

812-815

791-794

1003-1007

942-945

(Continued on inside back cover)

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