Coordination of a FP5 project and

necessary evolution towards the FP6 programme

Detal FP5 projectFP6 projects

DETAL : Detection of toxic algae

Objective : Rapid and sensitive fluorescent test for the tracking

of toxic algae in the marine environment

Six partners from 4 different countries

x

x

xx

x

x

Partner 2

Partner 1

Partner 4

Partners 3, 5 and 6

Algal collection

Oligonucleotide probes

Antibody probes

Chemscan analysis

Validation of the methodology

FP5 Project DETAL

FP5 Project DETAL

- Cooperation between the partners- Competence complementarity

- But no strong collaboration- No integration

Preparation of the FP6 programme

- New concepts : Integration and Structuration

- Broader projects than in FP5

- New tools : Networks of excellence and Integrated Projects

- Importance of mobility and training

Many projects in preparation

Presentation of two examples :

Network of excellence : Marine genomics

Integrated project : Comparative genomics of the cell cycle

Preparation of the FP6 programme

Network of Excellence : Marine genomics

Objective : To incorporate the science of genomics (and all its derived fields) into all areas of marine sciences ranging

from biological oceanography, ecology to aquaculture research through basic marine biology

Marine

Biology

Genomics

Marine genomics

Comparative genomics

Functional genomics

Environmental genomics

Metazoans

YeastsAnimalsPlants Brown

algaeDinoflagellates

CiliatesApicomplexa

Fungi RedAlgae Green lineage

Green algae

Heterokonts Alveolates

Marine genomics

Network of excellence

About 400 scientists expected

No direct support to sequencing or post-genomics programs

General integration of partners by a vertical organization through the 3 jointly executed research (JER)

Direct integration by an horizontal organization through specific nodes

Strong training program

Comparative genomics of the cell cycle

DrosophilaDrosophilaHumanHumanMouseMouse

Ecd

ysoz

oa

Lop

hotr

ocho

zoa

Metazoa PlantaFungi

YeastYeast

RizeRize ArabidopsisArabidopsis

O. O. tauritauri

PhyscomitrellaPhyscomitrella

Deuterostomians Protostomians Terrestrian plants Algae

Objective : Comparison of the basic mechanisms controlling cell division at a genome wide scale

Comparative genomics of the cell cycle

Selection of a model :-Relevant phylogenetic position-Genomics data available-Possible cell synchronization

Genome sequences Cell cycle transcriptome

In silico researchBioinformatics

Core cell cycleSpecies specific modifications

Functional analysis

Comparative genomics of cell cycle

Integrated project :- Direct support to research programs

-Between 12 to 15 partners

Strong common interests on the cell cycle :- Comparison of the different models- Development of common data bases

- Standardization of protocols for comparisons- Sharing of methodologies

Conclusion

FP6 concepts quite different to FP5s : cooperation and complementarity in FP5 versus integration and structuration in FP6

Networks of Excellence and Integrated Projects are new tools :Real opportunity to synchronize already existing research programsDevelopment or reinforcement of genomic programs in new fields

Many discussions and projects currently in preparation