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IFMBE Proceedings Vol. 32 Keith E. Herold, William E. Bentley, and Jafar Vossoughi (Eds.) 26th Southern Biomedical Engineering Conference SBEC 2010 April 30 - May 2, 2010 College Park, Maryland, USA 4^ Springer
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  • IFMBE Proceedings Vol. 32

    Keith E. Herold, William E. Bentley,

    and Jafar Vossoughi (Eds.)

    26th Southern Biomedical EngineeringConference SBEC 2010 April 30 - May 2, 2010

    College Park, Maryland, USA

    4^ Springer

  • Table of Contents

    Traumatic Brain Injury

    Traumatic Brain Injury in Rats Caused by Blast-Induced Hyper-Acceleration 1

    G. Fiskum, J. Hazelton, R. Gullapalli, W.L. Fowmey

    Early Metabolic and Structural Changes in the Rat Brain Following Trauma in vivo UsingMRI r,

    S. Xu, J. Zhuo, J. Racz, S. Roys, D. Shi, G. Fiskum, R. Gullapalli

    Principal Components of Brain Deformation in Response to Skull Acceleration: The Roles of

    Sliding and Tethering between the Brain and Skull !)

    Teresa M. Abney, Y. Aaron Feng, Robert Pless, Ruth J. Okamoto, Guy M. Genin, Philip V. Bayly

    Investigations into Wave Propagation in Soft Tissue VA

    M.F. Valdez, B. Balachandran

    Correlating Tissue Response with Anatomical Location of mTBI Using a Human Head Finite

    Element Model under Simulated Blast Conditions is

    T.P. Harrigan, J.C. Roberts, E.E. Ward, A.C. Merkle

    Human Surrogate Head Response to Dynamic Overpressure Loading in Protected and

    Unprotected Conditions 22

    A.C. Merkle, ID. Wing, J.C. Roberts

    Blast-Induced Traumatic Brain Injury: Using a Shock Tube to Recreate a Battlefield Injury inthe Laboratory 2li

    J.B. Long, L. Tong, R.A. Bauman, J.L. Atkins, A.J. Januszkiewicz, C. Riccio, R. Gharavi, R. Shoge,S. Parks, D. V. Ritzel, T.B. Bentley

    Wave Propagation in the Human Brain and Skull Imaged in vivo by MR Elastography HI

    E.H. Clayton, G.M. Genin, P. V. Bayly

    Cavitation as a Possible Traumatic Brain Injury (TBI) Damage Mechanism 154Andrew Wardlaw, Jack Goeller

    Prognostic Ability of Diffusion Tensor Imaging Parameters among Severely Injured TraumaticBrain Injury Patients ,'i,H

    Joshua F. Betz, Jiachen Zhuo, Anindya Roy, Kathirkamanthan Shanmuganathan, Rao P. Gullapalli

    Auditory Science

    Hair Cell Regeneration in the Mammalian Ear, Is Gene Therapy the Answer? 42

    Matthew W. Kelley

    Magnetoencephalography and Auditory Neural Representations 4f>

    J.Z. Simon, N. Ding

  • VIII Table of Contents

    Voice Pitch Processing with Cochlear Implants 49

    Monita Chatterjee, Shu-Chen Peng, Lauren Wawroski, Cherish Oberzut

    Transcranial Magnetic Stimulation as a Tool for Investigating and Treating Tinnitus 53G.F. Wittenberg

    Bioengineering Education

    A Course Guideline for Biomedical Engineering Modeling and Design for Freshmen 56

    W.C. Wong, E.B. Haase

    Classroom Nuclear Magnetic Resonance System 61

    C.L. Zimmerman, E.S, Boyden, S.C. Wasserrnan

    The Basics of Bioengineering Education 65

    Arthur T. Johnson

    HealthiManage: An Individualized Prediction Algorithm for Type 2 Diabetes Chronic Disease

    Control 67

    Salirn Chemlal, Sheri Colberg, Maria Satin-Smith, Eric Gyuricsko, Tom Hubbard, Mark W. Scerbo,Frederic D. McKenzie

    Cellular Engineering

    Dynamic Movement and Property Changes in Live Mesangial Cells by Stimuli 71

    Gi Ja Lee, Samjin Choi, Jeong Boon Park, Kyung Sook, Kim, Ilsung Clio, Sang Ho Lee, Hun Kuk Park

    Cooperative Interactions between Myosin II and Cortexillin I Mediated by Actin Filaments

    during Cellular Deformation 74

    Tianzhi Luo, Douglas N. Robinson

    Devices

    Constitutive Law for Miniaturized Quantitative Microdialysis 77

    C.-f. Chen

    Non-invasive Estimation of Intracranial Pressure by Means of Retinal Venous Pulsatility 81S. Mojtaba Golzan, Stuart L, Graham, Alberto Avolio

    Apparatus for Quantitative Slit-Lamp Ocular Fluorometry 85

    Jose P. Domingues, Isa Branco, Antonio M, Morgado

    Changes in Viscoelastic Properties of Latex Condoms Due to Personal Lubricants 89

    Srilekha Sarkar Das, Matthew Schwerin, Donna Walsh, Charles Tack, D. Coleman Richardson

    Towards the Objective Evaluation of Hand Disinfection 92Akos Lehotsky, Melinda Nagy, Tamds Haidegger

  • Table of Contents IX

    Neural Systems Engineering

    In vitro Models for Measuring Charge Storage CapacityK.F. Zaidi, Z.H. Benchekroun, S. Minnikanti, J, Pancrazio, N. Peixoto

    Discovery of Long-Latency Somatosensory Evoked Potentials as a Marker of Cardiac Arrest

    Induced Brain Injury II)IDan Wu, Jai Madhok, Young-Seok Choi, Xiaofeng Jia, Nitish V. Thakor

    In vivo Characterization of Epileptic Tissue with Time-Dependent, Diffuse Reflectance

    Spectroscopy lor.Nitin Yadav, Sanghoon Oh, Sanjeev Bhatia, John Ragheb, Prasanna Jayakar, Michael Duchowny,Wei-Chiang Lin

    Kinematics

    Effects of Initial Grasping Forces, Axes, and Directions on Torque Production during Circular

    Object Manipulation Hi'tJ. Huang, J.K. Shim

    Time Independent Functional Training of Inter-joint Arm Coordination Using the ARMin IIIRobot ll:f

    E.B. Brokaw, T. Nef, T.M. Murray, P.S. Lum

    Kinematic Analysis in Robot Assisted Femur Fracture Reduction: Fuzzy Logic Approach lis

    Wang Song, Chen Yonghua, Ye Ruihua, Yau WaiPan

    Compensation for Weak Hip Abductors in Gait Assisted by a Novel Crutch-Like Device 1'J'JJ.R. Borrelli, H.W. Haslach Jr.

    Nanotechnology

    Measuring in vivo Effects of Chemotherapy Treatment on Cardiac Capillary Permeability .... l'JHA. Fernandez-Fernandez, D.A. Carvajal, A.J. McGoron

    Nanoscale "DNA Baskets" for the Delivery of siRNA 13n

    A.C. Zirzow, M. Skoblov, A. Patanarut, C. Smith, A. Fisher, V. Chandhoke, A, Baranova

    Nanoscale Glutathione Patches Improve Organ Function V.i \

    Homer Nazeran, Sherry Blake-Greenberg

    Nanoscale Carnosine Patches Improve Organ Function 13*

    Homer Nazeran, Sherry Blake-Greenberg

    Multiple Lumiphore-Bound Nanoparticles for in vivo Quantification of Localized OxygenLevels M'J

    J.L. Van Druff, W. Zhou, E. Asman, J.B. Leach

    Ion-Mobility Characterization of Functionalized and Aggregated Gold Nanoparticles for DrugDelivery Ud

    D.-H. Tsai, L.F. Pease III, R.A. Zangmeister, S. Guha, M.J. Tarlov, M.R. Zachariah

  • X Table of Contents

    Implants

    Quantitative Mapping of Vascular Geometry for Implant Sites 150J.W. Karanian, 0. Lopez, D. Had, B. McDowell, M. Kreitz, J. Esparza, J. Vossoughi, O.A. Chiesa,W.F. Pritchard

    Failure Analysis and Materials Characterization of Hip Implants 154

    A.M. Bastidos, S.W. Stafford

    Nano-Wear-Particulates Elicit a Size and Dose Dependent Response by RAW 264.7 Cells .... 158

    Mrinal K. Musib, Subrata Saha

    Viscous Behavior of Different Concentrations of Bovine Calf Serum Used to Lubricate the

    Micro-textured CoCrMo Alloy Material before and after Wear Testing 161Geriel Ettienne-Modeste, Timmie Topoleski

    Progressive Wear Damage Analysis on Retrieved UHMWPE Tibial Implants 165

    N. Camacho, S. W. Stafford, L. Trueba Jr.

    Tissue Engineering

    Gum Arabic-Chitosan Composite Biopolymer Scaffolds for Bone Tissue Engineering 171

    R.A. Silva, P. Mehl, O.C. Wilson

    Modification of Hydrogel Scaffolds for the Modulation of Corneal Epithelial Cell

    Responses 175L.G. Reis, P. Pattekari, P.S. Sit

    Making of Functional Tissue Engineered Heart Valve 180S.S. Patel, Y.S. Morsi

    Ties That Bind: Evaluation of Collagen I and a-Chitin 183

    Tiffany Omokanwaye, Otto Wilson Jr.

    Chitosan/Poly (e-Caprolactone) Composite Hydrogel for Tissue Engineering Applications .... 188Xia Zhong, Chengdong Ji, Sergei G. Kazarian, Andrew Ruys, Fariba Dehghani

    Disease Modeling

    Modeling and Control of HIV by Computational Intelligence Techniques 192N. Bazyar Shourabi

    Mathematical Modeling of Ebola Virus Dynamics as a Step towards Rational Vaccine

    Design 196

    Sophia Banton, Zvi Roth, Mirjana Pavlovic

    Respiratory Impedance Values in Adults Are Relatively Insensitive to Mead Model LungCompliance and Chest Wall Compliance Parameters 201

    Bill Diong, Michael D. Goldman, Homer Nazeran

    A Systems Biology Model of Alzheimer's Disease Incorporating Spatial-temporal Distributionof Beta Amyloid 204

    G.R. Kyrtsos, J.S. Baras

  • Table of Contents XI

    A Mathematical Model of the Primary T Cell Response with Contraction Governed byAdaptive Regulatory T Cells 2(J!i

    S.N. Wilson, P. Lee, D. Levy

    A Mathematical Model for Microenvironmental Control of Tumor Growth 21'A

    A.R. Galante, D. Levy, C. Tomasetti

    Assessing the Usability of Web-Based Personal Health Records 217

    Pedro Gonzales, Binh Q. Tran

    Drug Delivery

    Real Time Monitoring of Extracellular Glutamate Release in Rat Ischemia Model Treated by

    Nimodipine 221E.K. Park, G.J. Lee, S.K. Choi, S. Choi, S.W. Rang, S.J. Chae, H.K. Park

    Targeted Delivery of Doxorubicin by PLGA Nanoparticles Increases Drug Uptake in CancerCell Lines 221

    Tingjun Lei, Supriya Sriniva.san, Yuan Tang, Romila Manchanda, Alicia Fernandez-Fernandez,Anthony J. Mcgoron

    Cellular Uptake and Cytotoxicity of a Novel ICG-DOX-PLGA Dual Agent PolymerNanoparticle Delivery System 22

  • XII Table of Contents

    The Measurement and Processing of EEG Signals to Evaluate Fatigue 258

    M.R. Yousefi Zoshk, M. Azarnoosh

    Modeling for the Impact of Anesthesia on Neural Activity in the Auditory System 262

    Z.B. Tan, L.Y. Wang, H. Wang, X.G. Zhang, J.S. Zhang

    Cortical Excitability Changes after Repetitive Self-regulated vs. Tracking Movements of theHand 266

    S.B. Godfrey, P.S. Lum, GN. Schabowsky, M.L. Harris-Love

    What the ENT Wants in the OR: Bioengineering Prospects 270

    D. A. Depireux, D.J. Eisenman

    An in vitro Biomechanical Comparison of Human Dermis to a Silicone Biosimulant

    Material 274

    I.D. Wing, H.A. Conner, P.J. Biermann, S.M. Belkoff

    Telemetric Epilepsy Monitoring and Seizures Aid 278K. Hameed, F. Azhar, I. Shahrukh, M. Muzammil, M. Aarnair, D. Mujeeb

    Spike Detection for Integrated Circuits: Comparative Study 282

    A. Sarje, P. Abshire

    Effect of Ambient Humidity on the Electrical Conductance of a Titanium Oxide Coating Being

    Investigated for Potential Use in Biosensors 286

    Jorge Torres, James Sweeney, Jose Barreto

    Brain Computer Interface in Cerebellar Ataxia 289

    G.I. Newman, S.H. Ying, Y.-S. Choi, H.-N. Kim, A. Presacco, M.V. Kothare, N.V. Thakor

    Biosensors

    Effects of Stray Field Distribution Generated by Magnetic Beads on Giant MagnetoresistanceSensor for Biochip Applications 293

    Kyung Sook Kim, Samjinn Choi, Gi Ja Lee, Dong Hyun Park, Jeong Hoon Park, II Sung Jo,Hun-Kuk Park

    Electrostatic Purification of Nucleic Acids for Micro Total Analysis Systems 297

    E. Hoppmann, I.M. White

    Applicability of Surface Enhanced Raman Spectroscopy for Determining the Concentration of

    Adenine and S-Adenosyl Homocysteine in a Microfluidic System 301

    Omar Bekdash, Jordan Betz, Yi Cheng, Gary W. Rubloff

    Integration of Capillary Ring Resonator Biosensor with PDMS Microfluidics for Label-Free

    Biosensing 305

    Farnoosh Farahi, Ian White

    Surface Plasmon-Coupled Emission from Rhodamine- 6G Aggregates for Ratiometric

    Detection of Ethanol Vapors 309

    R. Sai Sathish, Y. Kostov, G. Rao

  • Table of Contents XIII

    Formation of Dendritic Silver Substrates by Galvanic Displacement for Surface Enhanced

    Raman Spectroscopy 'M'.\

    Jordan Betz, Yi Cheng, Omar Bekdash, Susan Buckhout- White, Gary W. Rubloff

    High Specificity Binding of Lectins to Carbohydrate Functionalized Etched Fiber Bragg

    Grating Optical Sensors -517

    Geunmin Ryu, Mario Dagenais, Matthew T. Hurley, Philip DeShong

    Oximetry

    Oximetry and Blood Flow in the Retina 3'J1

    P. Lemaillet, A. Lompado, D. Duncan, Q.D. Nguyen, J.C. Ramella-Roman

    Monitoring and Controlling Oxygen Levels in Microfiuidic Devices lV2r>

    Peter C. Thomas, Srinivasa R. Raghavan, Samuel P. Forry

    An Imaging Pulse Oximeter Based on a Multi-Aperture Camera .iL"'

    Ali Basiri, Jessica C, Ramella-Roman

    Fluorescent Microparticles for Sensing Cell Microenvironment Oxygen Levels within 3D

    Scaffolds XVI

    Miguel A. Acosta, Jennie B. Leach

    Determination of in vivo Blood Oxygen Saturation and Blood Volume Fraction Using Diffuse

    Reflectance SpectroscopyP. Chen, W. Lin

    Image Analysis

    Fredholm Integral Equations in Biophysical Data Analysis 3 in

    P. Schuck

    High-Resolution Autofluorescence Imaging for Mapping Molecular Processes within the

    Human Retina H-H

    Martin Ehler, Zigurts Majumdar, Emily King, Julia Dobrosotskaya, Emily Chew, Wai Wong,Denise Cunningham, Wojciech Czaja, Robert F. Bonner

    Local Histograms for Classifying HfeE Stained Tissues

  • XIV Table of Contents

    Neuromechanics 8z Rehabilitation

    Optimization and Validation of a Biomechanical Model for Analyzing Running-SpecificProstheses 365

    Brian S. Baum, Roozbeh Borjian, You-Sin Kim, Alison Linberg, Jae Kun Shim

    Prehension Synergy: Use of Mechanical Advantage during Multi-finger Torque Production onMechanically Fixed- and Free-Object 368

    Jaebum Park, You-Sin Kim, Brian S. Baum, Yoon Hyuk Kim, Jae Kun Shim

    Modeling, Optimizing &: Monitoring

    Investigating Vortex Ring Propagation Speed Past Prosthetic Heart Valves: Implications for

    Assessing Valve Performance 372Ann Bailey, Michelle Beatty, Olga Pierrakos

    Transient Heat Transfer in a Dental Prosthesis Implanted in Mandibular Bone 376M.N. Ashtiani, R. Imani

    Characterization of Material Properties of Aorta from Oscillatory Pressure Tests 381)V. V. Romanov, K. Danish, S. Assari

    Quasi-static Analysis of Electric Field Distributions by Disc Electrodes in a Rabbit EyeModel 385

    S. Minnikanti, E. Cohen, N. Peixoto

    Optimizing the Geometry of Deep Brain Stimulating Electrodes 389J.Y. Zhang, W.M. Grill

    Exploratory Parcellation of fMRI Data Based on Finite Mixture Models and Self-Annealing-Expectation Maximization 393

    S. Maleki Balajoo, G.A. Hossein-Zadeh, H. Soltanian-Zadeh

    Computational Fluid Dynamic Modeling of the Airflow Perturbation Device 397S. Majd, J. Vossoughi, A. Johnson

    Biomaterials

    Mechanism and Direct Visualization of Electrodeposition of the Polysaccharide Chitosan 401Yi Cheng, Xiaolong Luo, Jordan Betz, Omar Bekdash, Gary W. Rubloff

    Chito-Cotton: Chitosan Coated Cotton-Based Scaffold 404

    0. Agubuzo, P. Mehl, O.C. Wilson, R. Silva

    Effects of Temperature on the Performance of Footwear Foams: Review of Developments 409M.R. Shariatmadari, R. English, G. Rothwell

    A Tissue Equivalent Phantom of the Human Torso for in vivo BiocompatibleCommunications 414

    David M. Peterson, Walker Turner, Kevin Pham, Hong Yu, Rizwan Bashirullah, Neil Euliano,Jeffery R. Fitzsimmons

  • Table of Contents XV

    Identification of Bacteria and Sterilization of Crustacean Exoskeleton Used as a

    Biomaterial 41,s

    Tiffany Omokanwaye, Donae Owens, Otto Wilson Jr.

    Neural Stem Cell Differentiation in 2D and 3D Microenvironments 422

    A. S. Ribeiro, E.M. Powell, J.B. Leach

    A Microfluidic Platform for Optical Monitoring of Bacterial Biofilms 42ii

    M.T. Meyer, V. Roy, W.E. Bentley, R. Ghodssi

    Conduction Properties of Decellularized Nerve Biomaterials 4HU

    M.G. Urbanchek, B.S. Shim, Z. Baghmanli, B. Wei, K. Schroeder, N.B. Langhals, R.M. Miriani,

    B. M. Egeland, D.R. Kipke, D.C. Martin, P.S. Cederna

    Reverse Cholesterol Transport (RCT) Modeling with Integrated Software Configurator AM

    S. Adhikari

    Biomechanics

    Modeling Linear Head Impact and the Effect of Brain-Skull Interface 4H7

    K. Laksari, S. Assari, K. Danish

    Mechanics of CSF Flow through Trabecular Architecture in the Brain 4 1(1

    Parisa Saboori, Catherine Gerrnanier, Ali Sadegh

    Impact of Mechanical Loading to Normal and Aneurysmal Cerebral Arteries 44-i

    M. Zoghi-Moghadam, P. Saboori, A. Sadegh

    Identification of Material Properties of Human Brain under Large Shear Deformation:

    Analytical versus Finite Element Approach 4 l,s

    C.D. Untaroiu, Q. Zhang, A.M. Damon, J.R. Crandall, K. Darvish, G. Paskoff, B.S. Shender

    Mechanisms of Traumatic Rupture of the Aorta: Recent Multi-Scale Investigations 4fVJ

    N.A. White, C.S. Shah, W.N. Hardy

    Head Impact Response: Pressure Analysis Simulation 451 i

    R.T. Cotton, P.G. Young, C.W. Pearce, L. Beldie, B. Walker

    Imaging

    An Introduction to the Next Generation of Radiology in the Web 2.0 World 4fi!l

    A. Moein, M. Malekmohammadi, K. Youssefi

    Novel Detection Method for Monitoring of Dental Caries Using Single Digital Subtraction

    Radiography Alu\

    J.H. Park, Y.S. Choi, G.J. Lee, S. Choi, K.S. Kim, D.H. Park, I. Cho, H.K. Park

    Targeted Delivery of Molecular Probes for in Vivo Electron Paramagnetic Resonance

    Imaging 4(i(i

    S.R. Burks, E.D. Barth, S.S. Martin, G.M. Rosen, H.J. Halpern, J.P.Y. Kao

  • XVI Table of Contents

    New Tools for Image-Based Mesh Generation of 3D Imaging Data 470P.G. Young, D. Raymont, V. Bui Xuan, R.T. Cotton

    Characterization of Speed and Accuracy of a Nonrigid Registration Accelerator on Pre- and

    Intraprocedural Images 473

    Raj Shekhar, William Plishker, Sheng Xu, Joclien Kruecker, Peng Lei, Aradhana Venkatesan,

    Bradford Wood

    Assessment of Kidney Structure and Function Using GRIN Lens Based Laparoscope with

    Optical Coherence Tomography 477

    C.W, Chen, J, Wierwille, M.L. Onozato, P.M. Andrews, M. Phelan, J. Bonn, Y. Chen

    Reliability of Structural Equation Modeling of the Motor Cortex in Resting State Functional

    MRI 481

    T. Kavallappa, S. Roys, A. Roy, J. Greenspan, R. Gullapalli, A. McMillan

    Quantitative Characterization of Radiofrequency Ablation Lesions in Tissue Using OpticalCoherence Tomography 485

    J. Wierwille, A. McMillan, R. Gullapalli, J. Desai, Y. Chen

    Clinically Relevant Hand Held Two Lead EEG Device 489

    E.M. O'Brien, R.L. Elliott

    A Simple Structural Magnetic Resonance Imaging (MRI) Method for 3D Mapping betweenHead Skin Tattoos and Brain Landmarks 493

    Mulugeta Semework

    Frame Potential Classification Algorithm for Retinal Data 496

    Jolm J. Benedetto, Wojciech Czaja, Martin Elder

    Raman-AFM Instrumentation and Characterization of SERS Substrates and Carbon

    Nanotubes 500

    Q. Vu, M.H. Zhao, E. Wellner, X. Truong, P.D. Smith, A.J. Jin

    A Novel Model of Skin Electrical Injury 504

    Thu T.A, Nguyen, AH Basin, J.W. Shupp, A.R. Pavlovich, M.H. Jordan, Z. Sanford,J.C. Ramella-Roman

    Design, Construction, and Evaluation of an Electrical Impedance Myographer 508

    K. Lweesy, L. Fraiwan, D. Hadarees, A. Jamil, E. Ramadan

    The Role of Imaging Tools in Biomedical Research: Preclinical Stent Implant Study 512

    W.F. Pritchard, M. Kreitz, 0. Lopez, D. Rad, B. McDowell, S. Nagaraja, M.L. Dreher, J. Esparza,J. Vossoughi, O.A. Chiesa, J. W. Karanian

    Hard Tissue and Posture

    Optimization of Screw Positioning in Mandible during Bilateral Sagittal Split OsteotomyUsing Finite Element Method 516

    A. Raeisi Najafi, A. Pashaei, S. Majd, I. Zoljanahi Oskui, B. Bohluli

  • Table of Contents XV11

    Extraction and Characterization of a Soluble Chicken Bone Collagen 5l'iiTiffany Omokanwaye, Otto Wilson Jr., Hoda Iravani, Pramodh Kariyawasam

    A Model for Human Postural Regulation fi'J-lYao Li, William S. Levine

    Development of an Average Chest Shape for Objective Evaluation of the Aesthetic Outcomein the Nuss Procedure Planning Process .VJs

    K.J. Rechowicz, R. Kelly, M. Goretsky, F. Frantz, S. Knisley, D. Nuss, F.D. McKenzie

    Sickle Cell and Blood Cell

    Sickle Hemoglobin Fiber Growth Rates Revealed by Optical Pattern Generation n;S'JZ. Liu, A. Aprelev, M. Zakharov, F.A. Ferrone

    Sickle Cell Occlusion in Microchannels f>;jt.A. Aprelev, W. Stephenson, H. Noh, M. Meier, M. MacDermott, N. Lerner, F.A. Ferrone

    Engineering Microfluidics Based Technologies for Rapid Sorting of White Blood Cells r».|uVinay Raj, Kranthi Kumar Bhavanam, Vahidreza Parichehreh, Palaniappan Sethu

    Peripheral Arterial Tonometry in Assessing Endothelial Dysfunction in Pediatric Sickle CellDisease Ml

    KM. Sivamurthy, C. Dampler, M. MacDermott, M. Meier, M. Cahill, L.L. Hsu

    Comparison of Shear Stress, Residence Time and Lagrangian Estimates of Hemolysis inDifferent Ventricular Assist Devices fi-ls

    K.H. Fraser, M.E. Taskin, T. Zhang, B.P. Griffith, Z.J. Wu

    Cancer

    Drug Resistance Always Depends on the Turnover Rate firrjC. Tomasetti, D. Levy

    Design and Ex Vivo Evaluation of a 3D High Intensity Focused Ultrasound System for TumorTreatment with Tissue Ablation T>T>u

    K. Lweesy, L. Fraiwan, M. Al-Shalabi, L. Mohammad, R. Al-Oglah

    The Dr. James W. Jacobson Symposium on Technologies for Cancer Diagnostics

    Clinical Applications of Multispectral Imaging Flow Cytometry .rjliiiH. Minderman, T.C. George, K.L. O'Loughlin, P.K. Wallace

    Multispectral Imaging, Image Analysis, and Pathology 5(51Richard M. Levenson

  • XVIII Table of Contents

    Sensitive Characterization of Circulating Tumor Cells for Improving Therapy Selection 568

    H. Ben Hsieh, George Somlo, Robyn Bennis, Paul Frankel, Robert T. Krivacic, Sean Lau, Janey Ly,Erich Schwartz, Richard H. Bruce

    Nanohole Array Sensor Technology: Multiplexed Label-Free Protein Binding Assays 572J. Cuiffi, R. Soong, S. Manolakos, S. Mohapatra, D. Larson

    Author Index 577

    Keyword Index 581


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