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Front Matter Source: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, No. 4 (Feb. 18, 1997), pp. i-x Published by: National Academy of Sciences Stable URL: http://www.jstor.org/stable/41280 . Accessed: 08/05/2014 09:18 Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at . http://www.jstor.org/page/info/about/policies/terms.jsp . JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact [email protected]. . National Academy of Sciences is collaborating with JSTOR to digitize, preserve and extend access to Proceedings of the National Academy of Sciences of the United States of America. http://www.jstor.org This content downloaded from 169.229.32.137 on Thu, 8 May 2014 09:18:44 AM All use subject to JSTOR Terms and Conditions
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Page 1: Front Matter

Front MatterSource: Proceedings of the National Academy of Sciences of the United States of America,Vol. 94, No. 4 (Feb. 18, 1997), pp. i-xPublished by: National Academy of SciencesStable URL: http://www.jstor.org/stable/41280 .

Accessed: 08/05/2014 09:18

Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at .http://www.jstor.org/page/info/about/policies/terms.jsp

.JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range ofcontent in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new formsof scholarship. For more information about JSTOR, please contact [email protected].

.

National Academy of Sciences is collaborating with JSTOR to digitize, preserve and extend access toProceedings of the National Academy of Sciences of the United States of America.

http://www.jstor.org

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Page 2: Front Matter

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PROCEEDINGS OF THE

NATIONAL ACADEMY OF SCIENCES

OF THE UNITED STATES OF AMERICA

February 18, 1997 Volume 94 / Number 4

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Page 3: Front Matter

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Page 4: Front Matter

Proceedings of the National ACademy of Sciences

of iht Unlt4 Slat" of Ameria

IFREE TRIAL 1ERIOI~ EMSI KARCH f-J11.

Brovse & Search Alt Issues: November 12, 1996 -

January7, 1997

_ Brov3e Collected Papen: I_kgkuI MUAx?ik

Curreiat tssue: (T ur u) -is Js 21v I 7a) 2 t 1 7 1997

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PHOTOGRAPH: ALEX JAMISON

Available online as of January 7, 1997 at

http://www.pnas.org

FREE access period until at least March 31, 1997

For further information please contact the PNAS Business Office

(202) 625-4747 (FAX)

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Page 5: Front Matter

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

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Page 6: Front Matter

PROCEEDINGS OF THE

NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Officers of the Academy

Editor-in-Chief

Editorial Board of the Proceedings

BRUCE ALBERTS, President JACK HALPERN, Vice President PETER H. RAVEN, Home Secretary F. SHERWOOD ROWLAND, Foreign Secretary RONALD L. GRAHAM, Treasurer

NICHOLAS R. COZZARELLI

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Page 7: Front Matter

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Page 8: Front Matter

PROCEEDINGS OF THE

NATIONAL ACADEMY OF SCIENCES

OF THE UNITED STATES OF AMERICA

February 18, 1997 Volume 94, Number 4 pp. 1049-1604

Table of Contents

Physical Sciences BIOCHEMISTRY

RNA-dependent phosphorylation of a nuclear RNA 1064-1068

CHEMISTRY binding protein Peter A. Fung, Roxanne Labrecque,

High-precision position-specific isotope analysis 1049-1053 and Thoru Pederson

MAH MT ICSa W. Rorso Micae G. ThomasfBrenn

Thomgas N.pCori soeandsJ.tThom reaof an active enzyme by the linkage of two 1069-1073

Comments on the article 'Persistent confusion of total 1603 protein modules entropy and chemical system entropy in chemical A. B.Nxn .S arn,adS.Bnoi thermodynamics (Correction) Nuclear integration of JAK/STAT and Ras/AP-1 1074-1079

John Ross signaling by CBP and pG300 Andrew B. Horvai, Lan Xu, Edward Korzus, Gyan Brard, Daniel Kalafus, Tina-Marie Mullen, David

MATHEMATICS W. Rose, Michael G. Rosenfeld, and Christopher K. Glass

Using a parity-sensitive sieve to count prime values of 1054-1058 a polynomial Native-like structure of a protein-folding intermediate 1080-1085

John Friedlander and Henryk lwaniec bound to the chaperonin GroEL Matthew S. Goldberg, Jing Zhang, Stacey Sondek, C. Robert Matthews, Robert 0. Fox,

Biological Sciences ~~~~~~~~and Arthur L. Horwich

Kinesin-73 in the nervous system of 1086-1091

APPLIED BIOLOGICAL SCIENCES Drosophila embryos Hsi-Ping Li, Zheng-Mei Liu, and Marshall Nirenberg

A new approach for containment of microorganisms: 1059-1063 Dual control of streptavidin expression by antisense p21-activated kinase has substrate specificity similar to 1092-1095 RNA and the T7 transcription system Acanthamoeba myosin I heavy chain kinase and

Przemyslaw Szafranski, Charlene M. Mello, Takeshi activates Acanthamoeba myosin I Sano, Cassandra L. Smith, David L. Kaplan, Hanna Brzeska, Ulla G. Knaus, Zhen-Yuan Wang, and Charles R. Cantor Gary M. Bokoch, and Edward D. Korn

v

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Page 9: Front Matter

Contents

Catalysis of protein folding by 1096-1100 symmetric chaperone complexes

Helmut Sparrer, Kerstin Rutkat, and Johannes Buchner

Characterization of two scleroderma autoimmune 1101-1106 antigens that copurify with human ribonuclease P

Paul S. Eder, Ramesh Kekuda, Viktor Stolc, and Sidney Altman

The effect of macromolecular crowding on 1107-1112 chaperonin-mediated protein folding

J6rg Martin and F.-Ulrich Hartl

A novel 3'-end repair mechanism in an RNA virus 1113-1118 Peter D. Nagy, Clifford D. Carpenter, and Anne E. Simon

Rapid determination of single base mismatch 1119-1123 mutations in DNA hybrids by direct electric field control

Ronald G. Sosnowski, Eugene Tu, William F. Butler, James P. O'Connell, and Michael J. Heller

Antifolate-resistant mutants of Plasmodium falciparum 1124-1129 dihydrofolate reductase

Worachart Sirawaraporn, Tanajit Sathitkul, Rachada Sirawaraporn, Yongyuth Yuthavong, and Daniel V. Santi

Purification and characterization of the 1130-1135 prothoracicotropic hormone of Drosophila melanogaster

Ae-Jung Kim, Guang-Ho Cha, Kyungjin Kim, Lawrence I. Gilbert, and Chung Choo Lee

Isoform-specific interactions of Na,K-ATPase subunits 1136-1141 are mediated via extracellular domains and carbohydrates

Gunther Schmalzing, Karina Ruhl, and Sergio M. Gloor

Identification of an animal w-3 fatty acid desaturase 1142-1147 by heterologous expression inArabidopsis

James P. Spychalla, Anthony J. Kinney, and John Browse

Sequence-specific RNA binding by an SR protein 1148-1153 requires RS domain phosphorylation: Creation of an SRp40-specific splicing enhancer

Roland Tacke, Yan Chen, and James L. Manley

Cryptic single-stranded-DNA binding activities of the 1154-1159 phage A P and Escherichia coli DnaC replication initiation proteins facilitate the transfer of E. coli DnaB helicase onto DNA

Brian A. Learn, Soo-Jong Um, Li Huang, and Roger McMacken

Novel pyridinium surfactants for efficient, nontoxic in 1160-1165 vitro gene delivery

Irene van der Woude, Anno Wagenaar, Arthur A. P. Meekel, Martin B. A. ter Beest, Marcel H. J. Ruiters, Jan B. F. N. Engberts, and Dick Hoekstra

In vivo control of respiration by cytochrome c oxidase 1166-1171 in wild-type and mitochondrial DNA mutation-carrying human cells

Gaetano Villani and Giuseppe Attardi

Death effector domain-containing herpesvirus and 1172-1176 poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis

John Bertin, Robert C. Armstrong, Sabine Ottilie, David A. Martin, Yu Wang, Sean Banks, Guang-Hua Wang, Tatiana G. Senkevich, Emad S. Alnemri, Bernard Moss, Michael J. Lenardo, Kevin J. Tomaselli, and Jeffrey I. Cohen

A single zinc finger motif in the silencing factor 1177-1182 REST represses the neural-specific type II sodium channel promoter

Jose Tapia-Ramirez, Bart J. L. Eggen, Maria J. Peral-Rubio, Juan J. Toledo-Aral, and Gail Mandel

Nucleosome packaging and nucleosome positioning 1183-1188 of genomic DNA

P. T. Lowary and J. Widom

Cloning and sequence analysis of a Bothrops jararaca 1189-1193 cDNA encoding a precursor of seven bradykinin-potentiating peptides and a C-type natriuretic peptide

Nobuhiro Murayama, Mirian A. F. Hayashi, Hiroaki Ohi, Luiza A. F. Ferreira, Vivian V. Hermann, Hiromi Saito, Yoshiaki Fujita, Shigesada Higuchi, Beatriz L. Fernandes, Tetsuo Yamane, and Antonio C. M. de Camargo

BIOPHYSICS

An endogenous calcium oscillator may control early 1194-1199 embryonic division

Craig A. Swanson, Adam P. Arkin, and John Ross

CELL BIOLOGY

Hepatitis C virus core protein shows a cytoplasmic 1200-1205 localization and associates to cellular lipid storage droplets

G. Barba, F. Harper, T. Harada, M. Kohara, S. Goulinet, Y. Matsuura, G. Eder, Zs. Schaff, M. J. Chapman, T. Miyamura, and C. Brechot

The adenovirus E4orf6 protein can promote 1206-1211 ElA/ElB-induced focus formation by interfering with p53 tumor suppressor function

Michael Nevels, Susanne Rubenwolf, Thilo Spruss, Hans Wolf, and Thomas Dobner

The proliferation potential protein-related (P2P-R) 1212-1217 gene with domains encoding heterogeneous nuclear ribonucleoprotein association and Rbl binding shows repressed expression during terminal differentiation

Michael M. Witte and Robert E. Scott

A system for mutation measurement in mammalian 1218-1223 cells: Application to y-irradiation

Theodore T. Puck, Robert Johnson, and Steen Rasumussen

Identification of a c-fos-induced gene that is related to 1603 platelet-derived growth factor/vascular endothelial growth factor family (Correction)

Maurizio Orlandini, Lucia Marconcini, Rebecca Ferruzzi, and Salvatore Oliviero

vi

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Page 10: Front Matter

Contents

DEVELOPMENTAL BIOLOGY

Microtubule-mediated transport of organelles and 1224-1229 localization of /3-catenin to the future dorsal side of Xenopus eggs

Brian A. Rowning, Jonathan Wells, Mike Wu, John C. Gerhart, Randall T. Moon, and Carolyn A. Larabell

Single-chain fusions of two unrelated homeodomain 1230-1234 proteins trigger pathogenicity in UJstilago maydis

Tina Romeis, Jorg Kamper, and Regine Kahmann

Drosophila Myc is oncogenic in mammalian cells and 1235-1240 plays a role in the diminutive phenotype

Nicole Schreiber-Agus, David Stein, Ken Chen, Jason S. Goltz, Leslie Stevens, and Ronald A. DePinho

Systematic isolation of peptide signal molecules 1241-1246 regulating development in hydra: LWamide and PW families

Toshio Takahashi, Yojiro Muneoka, Jan Lohmann, Maria S. Lopez de Haro, Gaby Solleder, Thomas C. G. Bosch, Charles N. David, Hans R. Bode, Osamu Koizumi, Hiroshi Shimizu, Masayuki Hatta, Toshitaka Fujisawa, and Tsutomu Sugiyama

ECOLOGY

Scaling regions for food web properties 1247-1251 Louis-Felix Bersier and George Sugihara

Strong density- and diversity-related effects help to 1252-1257 maintain tree species diversity in a neotropical forest

Christopher Wills, Richard Condit, Robin B. Foster, and Stephen P. Hubbell

Solar UVB-induced DNA damage and 1258-1263 photoenzymatic DNA repair in antarctic zooplankton

Kirk D. Malloy, Molly A. Holman, David Mitchell, and H. William Detrich III

EVOLUTION

Evolutionary mechanisms and population dynamics of 1264-1269 the third variable envelope region of HIV within single hosts

Yumi Yamaguchi and Takashi Gojobori

Evidence that eukaryotic triosephosphate isomerase is 1270-1275 of alpha-proteobacterial origin

Patrick J. Keeling and W. Ford Doolittle

The complete mitochondrial genome of the wallaroo 1276-1281 (Macropus robustus) and the phylogenetic relationship among Monotremata, Marsupialia, and Eutheria

Axel Janke, Xiufeng Xu, and Ulfur Arnason

The strength of indirect selection on 1282-1286 female mating preferences

M. Kirkpatrick and N. H. Barton

Intron positions correlate with module boundaries in 1603 ancient proteins (Correction)

Sandro Jose de Souza, Manyuan Long, Lloyd Schoenbach, Scott William Roy, and Walter Gilbert

GENETICS

Adenovirus-mediated gene transfer and expression of 1287-1292 human f3-glucuronidase gene in the liver, spleen, and central nervous system in mucopolysaccharidosis type VII mice

Toya Ohashi, Kazuhiko Watabe, Keiko Uehara, William S. Sly, Carole Vogler, and Yoshikatsu Eto

Mutations in the mariner transposase: The D,D(35)E 1293-1297 consensus sequence is nonfunctional

Allan R. Lohe, Daniel De Aguiar, and Daniel L. Hartl

Triplet repeat polymorphism in the transmembrane 1298-1303 region of the MICA gene: A strong association of six GCT repetitions with Behcet disease

Nobuhisa Mizuki, Masao Ota, Minoru Kimura, Shigeaki Ohno, Hitoshi Ando, Yoshihiko Katsuyama, Masaaki Yamazaki, Koji Watanabe, Kaori Goto, Satoshi Nakamura, Seiamak Bahram, and Hidetoshi Inoko

High-resolution functional mapping of a cloned gene 1304-1309 by genetic footprinting

Ila R. Singh, Rachel Adams Crowley, and Patrick 0. Brown

Germ-line knockout heterokaryons of an essential 1310-1315 ae-tubulin gene enable high-frequency gene replacement and a test of gene transfer from somatic to germ-line nuclei in Tetrahymena thermophila

Bing Hai and Martin A. Gorovsky

Transcriptional regulation in Archaea: In vivo 1316-1320 demonstration of a repressor binding site in a methanogen

Rachel Cohen-Kupiec, Carrine Blank, and John A. Leigh

A genetic system to identify DNA polymerase 1321-1326 f3 mutator mutants

Stacy L. Washington, Margaret S. Yoon, Alexander M. Chagovetz, Shu-Xia Li, Caroline A. Clairmont, Bradley D. Preston, Kristin A. Eckert, and Joann B. Sweasy

Evidence for a role for DNA polymerase /3 in 1327-1331 mammalian meiosis

Annemieke W. Plug, Caroline A. Clairmont, Eva Sapi, Terry Ashley, and Joann B. Sweasy

An unusual histone H3 specific for early macronuclear 1332-1337 development in Euplotes crassus

Carolyn L. Jahn, Zhong Ling, Christopher M. Tebeau, and Lawrence A. Klobutcher

IMMUNOLOGY

Antigen therapy eliminates T cell inflammation by 1338-1343 apoptosis: Effective treatment of experimental autoimmune neuritis with recombinant myelin protein P2

Andreas Weishaupt, Ralf Gold, Stefanie Gaupp, Gerhard Giegerich, Hans-Peter Hartung, and Klaus V. Toyka

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Allergen-induced bronchial hyperreactivity and 1344-1349 eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma

Paul D. Mehlhop, Matthijs van de Rijn, Alison B. Goldberg, Joanne P. Brewer, Viswanath P. Kurup, Thomas R. Martin, and Hans C. Oettgen

Allergic airway sensitization induces T cell activation 1350-1355 but not airway hyperresponsiveness in B cell-deficient mice

E. Hamelmann, A. T. Vella, A. Oshiba, J. W. Kappler, P. Marrack, and E. W. Gelfand

Identification of the B cell superantigen-binding site 1356-1360 of HIV-1 gpl20

Saoussen Karray and Moncef Zouali

Highly purified CD25- resting T cells cannot be 1361-1365 infected de novo with HIV-1

Chin-Sheng Chou, Octavio Ramilo, and Ellen S. Vitetta

Graft-versus-host-disease-associated lymphoid 1366-1371 hypoplasia and B cell dysfunction is dependent upon donor T cell-mediated Fas-ligand function, but not perforin function

Matthew B. Baker, Richard L. Riley, Eckhard R. Podack, and Robert B. Levy

Shuttling of initiating kinase between discrete 1372-1377 aggregates of the high affinity receptor for IgE regulates the cellular response

Chikako Torigoe, Byron Goldstein, Carla Wofsy, and Henry Metzger

In vivo accumulation of the same anti-melanoma T 1378-1383 cell clone in two different metastatic sites

Makoto Hishii, David Andrews, Lenora A. Boyle, Johnson T. Wong, Franco Pandolfi, Peter J. van den Elsen, and James T. Kurnick

A complex major histocompatibility complex D locus 1384-1389 variant generated by an unusual recombination mechanism in mice

Theodore J. Yun, Roger W. Melvold, and Larry R. Pease

CD30 induction of human immunodeficiency virus 1390-1395 gene transcription is mediated by TRAF2

Erdyni N. Tsitsikov, Dowain A. Wright, and Raif S. Geha

Clade B-based HIV-1 vaccines elicit cross-clade 1396-1401 cytotoxic T lymphocyte reactivities in uninfected volunteers

Guido Ferrari, Will Humphrey, M. Juliana McElrath, Jean-Louis Excler, Anne-Marie Duliege, Mary Lou Clements, Lawrence C. Corey, Dani P. Bolognesi, and Kent J. Weinhold

MEDICAL SCIENCES

Intestinal tumorigenesis is suppressed in mice lacking 1402-1407 the metalloproteinase matrilysin

Carole L. Wilson, Kathleen J. Heppner, Patricia A. Labosky, Brigid L. M. Hogan, and Lynn M. Matrisian

Developmental analysis and subcellular localization of 1408-1413 the murine homologue of ELL

Michael J. Thirman, Emily B. Diskin, Steven S. Bin, Hon S. Ip, Jacqueline M. Miller, and M. Celeste Simon

Recombinational construction in Escherichia coli of 1414-1419 infectious adenoviral genomes

Joel Crouzet, Laurent Naudin, C6cile Orsini, Emmanuelle Vigne, Lucy Ferrero, Aude Le Roux, Patrick Benoit, Martine Latta, Christophe Torrent, Didier Branellec, Patrice Denefle, Jean-Fran?ois Mayaux, Michel Perricaudet, and Patrice Yeh

Recovery of pituitary function after treatment with a 1420-1425 targeted cytotoxic analog of luteinizing hormone-releasing hormone

Magdolna Kovacs, Andrew V. Schally, Attila Nagy, Miklos Koppan, and Kate Groot

Persistent expression of human clotting factor IX from 1426-1431 mouse liver after intravenous injection of adeno-associated virus vectors

Dwight D. Koeberl, Ian E. Alexander, Christine L. Halbert, David W. Russell, and A. Dusty Miller

Zinc porphyrins: Potent inhibitors of hematopoieses in 1432-1436 animal and human bone marrow

John D. Lutton, Nader G. Abraham, George S. Drummond, Richard D. Levere, and Attallah Kappas

Regulation of DNA damage-induced apoptosis by the 1437-1440 c-Abl tyrosine kinase

Zhi-Min Yuan, Yinyin Huang, Takatoshi Ishiko, Surender Kharbanda, Ralph Weichselbaum, and Donald Kufe

Initiation of liver growth by tumor necrosis factor: 1441-1446 Deficient liver regeneration in mice lacking type I tumor necrosis factor receptor

Yasuhiro Yamada, Irina Kirillova, Jacques J. Peschon, and Nelson Fausto

The Epstein-Barr virus LMP1 amino acid sequence 1447-1452 that engages tumor necrosis factor receptor associated factors is critical for primary B lymphocyte growth transformation

Kenneth M. Izumi, Kenneth M. Kaye, and Elliott D. Kieff

Differential suppression by protease inhibitors and 1603 cytokines of apoptosis induced by wild-type p53 and cytotoxic agents (Correction)

Joseph Lotem and Leo Sachs

MICROBIOLOGY

A bacterial basic region leucine zipper histidine kinase 1453-1458 regulating toluene degradation

Peter C. K. Lau, Ying Wang, Ashok Patel, Diane Labbe, Helene Bergeron, Roland Brousseau, Yasuo Konishi, and Merriann Rawlings

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NEUROBIOLOGY

BNaC1 and BNaC2 constitute a new family of human 1459-1464 neuronal sodium channels related to degenerins and epithelial sodium channels

Jaime Garcia-Afioveros, Bruce Derfler, Janine Neville-Golden, Bradley T. Hyman, and David P. Corey

A binding site for Pax proteins regulates expression of 1465-1470 the gene for the neural cell adhesion molecule in the embryonic spinal cord

Brent D. Holst, Yibin Wang, Frederick S. Jones, and Gerald M. Edelman

Suckling and sucrose ingestion suppress persistent 1471-1475 hyperalgesia and spinal Fos expression after forepaw inflammation in infant rats

K. Ren, E. M. Blass, Q.-q. Zhou, and R. Dubner

Behavioral effects of estrogen receptor gene 1476-1481 disruption in male mice

Sonoko Ogawa, Dennis B. Lubahn, Kenneth S. Korach, and Donald W. Pfaff

Morphological plasticity of dendritic spines in central 1482-1487 neurons is mediated by activation of cAMP response element binding protein

Diane D. Murphy and Menahem Segal

Ataxia and altered dendritic calcium signaling in mice 1488-1493 carrying a targeted null mutation of the calbindin D28k gene

Matti S. Airaksinen, Jens Eilers, Olga Garaschuk, Hans Thoenen, Arthur Konnerth, and Michael Meyer

A post-tetanic time window for the reinforcement of 1494-1499 long-term potentiation by appetitive and aversive stimuli

Thomas Seidenbecher, Klaus G. Reymann, and Detlef Balschun

Progressive decline in avoidance learning paralleled by 1500-1505 inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain

Charles J. Heyser, Eliezer Masliah, Ana Samimi, lain L. Campbell, and Lisa H. Gold

Modulation by neurotransmitters of catecholamine 1506-1511 secretion from sympathetic ganglion neurons detected by amperometry

Duk-Su Koh and Bertil Hille

Molecular determinants of inactivation and G protein 1512-1516 modulation in the intracellular loop connecting domains I and II of the calcium channel ag1A subunit

Stefan Herlitze, Gregory H. Hockerman, Todd Scheuer, and William A. Catterall

Relative numbers of cortical and brainstem inputs to 15 17-1520 the lateral geniculate nucleus

Alev Eri~ir, Susan C. Van Horn, and S. Murray Sherman

Brain-derived neurotrophic factor regulates expression 1521-1526 of androgen receptors in perineal motoneurons

Hussien A. Al-Shamma and Arthur P. Arnold

Identification of PN1, a predominant 1527-1532 voltage-dependent sodium channel expressed principally in peripheral neurons

Juan J. Toledo-Aral, Brenda L. Moss, Zhi-Jun He, Adam G. Koszowski, Teri Whisenand, Simon R. Levinson, John J. Wolf, Inmaculada Silos-Santiago, Simon Halegoua, and Gail Mandel

Pleiotropic effects of a disrupted K+ channel gene: 1533-1538 Reduced body weight, impaired motor skill and muscle contraction, but no seizures

Chi Shun Ho, Robert W. Grange, and Rolf H. Joho

Co-expression of the neuronal 6a7 and L247T 6a7 1539-1543 mutant subunits yields hybrid nicotinic receptors with properties of both wild-type 6a7 and a7 mutant homomeric receptors

E. Palma, F. Eusebi, and R. Miledi

Opiate receptor knockout mice define y receptor 1544-1549 roles in endogenous nociceptive responses and morphine-induced analgesia

Ichiro Sora, Nobuyuki Takahashi, Masahiko Funada, Hiroshi Ujike, Randal S. Revay, David M. Donovan, Lucinda L. Miner, and George R. Uhl

Amyloid precursor protein processing and Af342 1550-1555 deposition in a transgenic mouse model of Alzheimer disease

K. Johnson-Wood, M. Lee, R. Motter, K. Hu, G. Gordon, R. Barbour, K. Khan, M. Gordon, H. Tan, D. Games, I. Lieberburg, D. Schenk, P. Seubert, and L. McConlogue

Interconversion of red opsin isoforms by the 1556-1561 cyclophilin-related chaperone protein Ran-binding protein 2

Paulo A. Ferreira, Tomoko A. Nakayama, and Gabriel H. Travis

PHARMACOLOGY

Characterization of the permeability barrier of human 1562-1567 skin in vivo

Fabrice Pirot, Yogeshvar N. Kalia, Audra L. Stinchcomb, Garrett Keating, Annette Bunge, and Richard H. Guy

PHYSIOLOGY

Stabilization of ion selectivity filter by pore loop ion 1568-1572 pairs in an inwardly rectifying potassium channel

Jian Yang, Mei Yu, Yuh Nung Jan, and Lily Yeh Jan

Dependence of intracellular signaling and 1573-1578 neurosecretion on phospholipase D activation in immortalized gonadotropin-releasing hormone neurons

Lixin Zheng, Lazar Z. Krsmanovic, Leoncio A. Vergara, Kevin J. Catt, and Stanko S. Stojilkovic

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PLANT BIOLOGY

Mechanism of photosystem II photoinactivation and 1579-1584 DI protein degradation at low light: The role of back electron flow

Nir Keren, Alexander Berg, Paul J. M. van Kan, Haim Levanon, and Itzhak Ohad

Plastoquinol at the quinol oxidation site of reduced 1585-1590 cytochrome bf mediates signal transduction between light and protein phosphorylation: Thylakoid protein kinase deactivation by a single-turnover flash

Alexander V. Vener, Paul J. M. van Kan, Peter R. Rich, Itzhak Ohad, and Bertil Andersson

Why do mitochondria synthesize fatty acids? Evidence 1591-1596 for involvement in lipoic acid production

Hajime Wada, David Shintani, and John Ohlrogge

Redox chains in chloroplast envelope membranes: 1597-1602 Spectroscopic evidence for the presence of electron carriers, including iron-sulfur centers

Pascale Jager-Vottero, Albert-Jean Dorne, Jeanne Jordanov, Roland Douce, and Jacques Joyard

AUTHOR INDEX xi-xiii

INFORMATION FOR AUTHORS xiv-xv

SIZING WORKSHEET xvi

COPYRIGHT ASSIGNMENT FORM xvii

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