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Front Matter Source: Proceedings of the National Academy of Sciences of the United States of America, Vol. 75, No. 6 (Jun., 1978), pp. v-x Published by: National Academy of Sciences Stable URL: http://www.jstor.org/stable/68273 . Accessed: 08/05/2014 12:13 Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at . http://www.jstor.org/page/info/about/policies/terms.jsp . JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact [email protected]. . National Academy of Sciences is collaborating with JSTOR to digitize, preserve and extend access to Proceedings of the National Academy of Sciences of the United States of America. http://www.jstor.org This content downloaded from 169.229.32.137 on Thu, 8 May 2014 12:13:27 PM All use subject to JSTOR Terms and Conditions
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Front MatterSource: Proceedings of the National Academy of Sciences of the United States of America,Vol. 75, No. 6 (Jun., 1978), pp. v-xPublished by: National Academy of SciencesStable URL: http://www.jstor.org/stable/68273 .

Accessed: 08/05/2014 12:13

Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at .http://www.jstor.org/page/info/about/policies/terms.jsp

.JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range ofcontent in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new formsof scholarship. For more information about JSTOR, please contact [email protected].

.

National Academy of Sciences is collaborating with JSTOR to digitize, preserve and extend access toProceedings of the National Academy of Sciences of the United States of America.

http://www.jstor.org

This content downloaded from 169.229.32.137 on Thu, 8 May 2014 12:13:27 PMAll use subject to JSTOR Terms and Conditions

JUNE 1978

VOLUME 75

NUMBER 6

OF

Proceedings OF THE

National Academy of Sciences

OF THE UNITED STATES OF AMERICA

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THE PROCEEDINGS OF THE

National Academy of Sciences OF THE UNITED STATES OF AMERICA

Officers of the Academy

PHILIP HANDLER President SAUNDERS MAC LANE Vice President DAVID R. GODDARD Home Secretary GEORGE S. HAMMOND Foreign Secretary E. R. PIORE Treasurer

Editorial Board of the Proceedings

ROBERT L. SINSHEIMER Chairman ROBERT M. SOLOW Vice Chairman HARRISON SHULL Vice Chairman DAVID R. GODDARD Home Secretary GEORGE S. HAMMOND Foreign Secretary ER R. PIORE Treasiurpr

K. FRANK AUSTEN ALEXANDER G. BEARN P. D. BOYER JULIUS H. COMROE, JR. JOHN E. DOWLING HARRY EAGLE

RICHARD M. HELD HENRY S. KAPLAN

S. M. LIPSET EUGENE P. ODUM ALEXANDER RICH E. R. STADTMAN ELIAS M. STEIN HOWARD M. TEMIN JAMES TOBIN CHARLES H. TOWNES

Managing Editor: BERNARD K. FORSCHER Associate Editor: GARY T. COCKS Associate Editor: MURRIE W. BURGAN Associate Editor: SHEILA L. ROSENTHAI

Editorial correspondence: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, 2101 Constitution Avenue, Washington, DC 20418.

Business correspondence: Circulation Office of the PROCEEDINGS, National Academy of Sciences, 2101 Constitution Avenue, Washington, DC 20418.

Copyright: The National Academy of Sciences has copyrighted this journal as a collective work and does not own copyrights for individual articles. For reprints of individual articles, requests should be addressed to the authors. Microforms of complete volumes are available to regular subscribers only and may be obtained from University Microfilms, Xerox Corporation, Ann Arbor, MI 48103.

Subscriptions: All correspondence concerning subscriptions should be addressed to the Circulation Office of the Proceedings. Subscriptions are entered on a calendar year basis only. The 1978 subscription rate is $60. Subscribers are requested to notify the Circulation Office of the Proceedings 6 weeks in advance of any change of address; also the local postmaster. The Academy is not responsible for nonreceipt of issues because of improper address unless a change of address is on file. The notice of address change should list both the old and new addresses. Claims for replacement copies will not be honored more than 60 days after the issue date for domestic subscribers and not more than 90 days after the issue date for foreign sub- scribers.

Back Issues (Volumes 1-69, through December 1972) are available from Walter J. Johnson, Inc., 355 Chestnut Street, Norwood, NJ 07648. Prices are available from that organization upon request. Back Issues (Volumes 70-75, January 1973 and thereafter) are available from the Circulation Office of the Proceedings. The price of a single issue is $7.50.

Second class postage paid at Washington, DC, and at additional mailing offices. PRINTED IN THE USA

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA is published monthly by THE NATIONAL ACADEMY OF SCIENCES, 2101 Constitution Avenue, Washington, DC 20418

(C: 1978 by THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.

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A UTHOR INDEX, JUNE 1978

Abdelnoor, A. M. 2893 Adamany, A. M. 2727 Adams, P. R. 2994 Agnew, W. S. 2606 Aguiar, J. M. 2945 Almassy, R. J. 2674 Altura, B. M. 2941 Alving, C. R. 2959 Antoniades, H. N. 2839 Armelin, H. A. 2805 Armelin, M. C. S. 2805 Asakawa, T. 2684 Asher, D. M. 2969 Baltimore, D. 2732 Bell, J. R. 2722 Benacerraf, B. 2914 Bennett, J. C. 2708 Bergstrand, S. J. 2636 Beutler, E. 2825 Beverley, P. C. L. 2897 Bhown, A. S. 2708 Biel, S. I. 2937 B3lack, I. B. 2986 Blumenfeld, 0. 0. 2727 Boissard, C. 2772 Bossart, J. F. 2641 Boublik, M. 2829 Boxer, S. G. 2563 Brabson, J. S. 2606 Broach, J. R. 2878 Broome, S. 2746 Brown, D. D. 2849 Brown, P. W. 2969 Bundy, G. L. 2689 Burris, R. H. 2699 Butler, J. DeB. 3009 Butler, R. C. 2893 Buzash-Pollert, E. 2741 Cardasis, C. A. 2781 Cassel, D. 2669 Cerami, A. 2918 Cerf, R. 2755 Chan-Palay, V. 2977 Chapman, W. L., Jr.

2959 Chen, K. H. 2945 Chevalier, G. 2772 Chiappinelli, V. A. 2999 Clark, J. H. 2781 Closs, G. L. 2563 Cochard, P. 2986 Cohen, J. J. 2902 Coligan, J. E. 2909 Coon, H. G. 2969 Costa, E. 2991 Croce, C. M. 2883 Cronmiller, C. 2834 Custer, R. P. 2834 Das, M. 2644 DeHaan, R. L. 2776 de Haro, C. 2713 DeLuca, H. F. 2603 DeSimone, J. 2937 Dickerson, R. E. 2674 Dina, D. 2694 Dorf, M. E. 2914 Dunn, J. J. 2741 Edelman, G. M. 2750 Elsbach, P. 2955 Epner, E. 2795 Evans, D. R. 2654 Ewenstein, B. M. 2909 Eyring, H. 2549 Faller, D. V. 2964 Fernandes, G. 2888 Fihach, B. 2795

Field, M. 2800 Fischbach, G. D. 3004 F?itzpatrick, F. A. 2689 Fox, C. F. 2644 Fox, T. 0. 2664 Freed, H. J. 2864 Furlong, D. 2764 Gajdusek, D. C. 2969 Gardner, M. B. 2972 Gething, M. J. 2737 Getzoff, E. D. 2574 Gibbs, C. J., Jr. 2969 Gilbert, W. 2746 Gillin, J. C. 2991 Gisiger, V. 2588 Glitzer, M. S. 2636 Goidl, E. A. 2897 Goldstein, M. 2986 Gronatas, N. K. 2815 Good, R. A. 2888 Gordon, M. A. 2902 Gottesman, M. M. 2767 Graf, L. H., Jr. 2800 Grant, P. R. 2854 Greenspan, J. S. 2945 Gruzenski, G. M. 2785 Gruinto, B. 2825 Gurdon, J. B. 2849 Habener, J. F. 2616 Hageman, R. V. 2699 Halevy, S. 2941 Hanawalt, P. C. 2598 Hanson, W. L. 2959 Hardin, J. W. 2781 Hata, R.-i. 2790 Hearst, J. E. 2703 HFeller, P. 2937 H[ellmann, W. 2829 Hendricks, L. D. 2959 Herrick, G. 2626 Hirota, Y. 2631 Hirschmann, R. 2636 Ho, R.-j. 2684 Holaday, J. W. 2923 Holly, F. W. 2636 Hong, J. S. 2991 Hood, L. E. 2722 Hopkins, N. 2964 Hopper, J. E. 2878 Huberman, E. 2864 Huebner, K. 2883 Huebner, R. J. 2972 Hunkapiller, M. W. 2722 Hunter, E. 2708 Itzicovitch, L. 2933 Jelinek, W. R. 2679 Johnson, F. H. 2611 Joseph, K. C. 2815 Kaplan, L. 2955 Kariya, B. 2810 Karle, J. 2545 Karnovsky, M. J. 3004 Kefalides, N. A. 2621 Kemper, B. 2616 Kidson, C. 2969 Kim, S. U. 2815 Kimura, M. 2868 Kindt, T. J. 2909 Kipps, T. J. 2914 Kirby, E. 2621 Kirk, T. 2621 Komiskey, H. L. 2641 Konisky, J. 2579 Kontiainen, S. 2897 Koshland, D. B., Jr.

2820

Krieger, D. T. 2950 Kronenberg, H. M. 2616 Krupp, M. N. 2593 Kuhl, W. 2825 Laburthe, M. 2772 Lagunoff, D. 2785 Laird, W. J. 2800 Lalley, P. 3009 Lamm, M. E. 2928 Landfear, S. M. 2654 Langenbach, R. 2864 Leong, K. 2732 Levi, G. 2981 Levinson, S. R. 2606 Li, C. H. 2923 Lin, L.-C. 2649 Linschitz, H. 2563 Liotta, A. S. 2950 Lipscomb, W. N. 2654 Liskay, R. M. 2873 Livingston, J. N. 2593 Loh, H. H. 2923 Lundy-Douglas, K. 2549 Lynch, R. E. 2541 Macarak, E. J. 2621 McClain, D. A. 2750 McConnell, H. M. 2759 McCormick, A. M. 2603 McWilliams, M. 2928 Maness, P. F. 2750 Marcu, K. B. 2883 Marks, P. A. 2795 Maruyama, I. N. 2631 Massoulie, J. 2588 Mateo, P. L. 2584 Matsuhashi, M. 2631 Matsumoto, F. 2825 Meshorer, A. 2933 Miller, D. D. 2641 Mintz, B. 2834 Miranda, M. 2888 Monnier, V. M. 2918 Moreau, M.-C. 2969 Mukherjee, A. B. 3009 Murgita, R. A. 2897 Napoli, J. L. 2603 Nathan, R. D. 2776 Nathenson, S. G. 2909 Nishimura, Y. 2631 Nisizawa, T. 2909 Nowotny, A. 2893 Nudel, U. 2795 Nutt, R. F. 2636 Ochoa, S. 2713 Ohta, T. 2868 Orloff, S. 3009 Padykula, H. A. 2781 Palay, S. L. 2977 Paleveda, W. J. 2636 Pastan, I. 2659 Patel, D. J. 2553 Patil, P. N. 2641 Periasamy, N. 2563 Perry, R. P. 2883 Pfeuffer, T. 2669 Phillips-Quagliata, J. M.

2928 Pledger, W. J. 2839 Potts, J. T., Jr. 2616 Prescott, D. M. 2873 Putnam, F. W. 2649 Raftery, M. A. 2606 Raines, E. 2810 PRaiteri, M. 2981 Rasheed, 5. 2972 Reisner, Y. 2933

v

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AUTHOR INDEX, JUNE 1978

Rice, J. R. 2541 Rich, A. 2616 Richardson, D. C. 2574 Richardson, J. S. 2574 Rifkind, R. A. 2795 Rivest, M.-J. 2810 Rommelaere, J. 2964 Rose, J. K. 2732 Rosenblatt, M. 2616 Ross, R. 2810 Rosselin, G. 2772 Rousset, M. 2772 Roux, M. E. 2928 Rouzer, C. A. 2918 Rowe, L. B. 2878 Rubik, B. A. 2820 Ruiz, J. 2684 Sakmann, B. 2994 Salmon, J. 2795 Saperstein, R. 2636 Sato, V. L. 2844 Schelly, Z. A. 2549 Scher, C. D. 2839 Schlessinger, J. 2659 Schnoes, H. K. 2603 Schoen, R. 2567 Schulman, J. D. 3009 Seale, R. L. 2717 Seeberg, E. 2569

Sharon, N. 2933 Shechter, Y. 2659 Shen, C. 2553 Shimomura, 0. 2611 Siegel, R. C. 2945 Slavkin, H. C. 2790 Smith, B. A. 2759 Smith, C. A. 2598 Smith, J. 2888 Smith, P. L. 2800 Steck, E. A. 2959 Stevens, V. J. 2918 Stieber, A. 2815 Stiles, C. D. 2839 Storb, U. 2905 Strauss, J. H. 2722 Studier, F. W. 2741 Sturtevant, J. M. 2584 Suda, T. 2950 Swartz, G. M., Jr. 2959 Takagaki, Y. 2631 Tamaki, S. 2631 Terada, M. 2795 Thurlow, D. L. 2859 Tokuda, H. 2579 Torchiana, M. 2636 Trachsel, H. 2732 Triche, T. 3009 Uehara, H. 2909

Valbuena, 0. 2883 Veber, D. F. 2636 Vigny, M. 2588 Vogel, A. 2810 Waits, V. B. 2959 Ward, J. C. 2568 Warshel, A. 2558 Waterfield, M. D. 2737 Wei, E. 2923 Weigert, M. 2883 Weiss, J. 2955 Weisz-Carrington, P.

2928 Wesley, R. D. 2626 White, J. M. 2737 Wiesehahn, G. 2703 Wigzell, H. 2897 Willingham, M. C. 2659 Wilson, I. B. 2902 Woodbury, R. G. 2785 Wysocki, L. J. 2844 Yang, H.-Y. T. 2991 Yau, S.-T. 2567 Yee, A. G. 3004 Yunis, E. J. 2888 Zigmond, R. E. 2999 Zimmermann, R. A.

2859 Zweibaum, A. 2772

vi

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Contents (Continued from page viii)

2969-2971 Chev Kidson, Marie-Claude Moreau, David M. Asher, Paul W. Brown, Hayden G. Coon, D. Carleton Galdusek, and Clarence J. Gibbs, Jr.

Cell fusion induced by scrapie and Creutzfeldt-Jakob virus-infected brain preparations (fusion/membrane/subacute spongiform encephalopathies)

2972-2976 Suraiya Rasheed, Murray B. Gardner, and Robert J. Huebner In vitro isolation of stable rat sarcoma viruses (transforming type C viruses/chemical carcinogenesis/endogenous transforming

(src) genes/viral recombination/tumor antigens)

NEUROBIOLOGY

2977-2980 Victoria Chan-Palay and Sanford L. Palay Ultrastructural localization of y-aminobutyric acid receptors in the mammalian central nervous system by means of [3H]muscimol

binding (cerebellar cortex/nuclei/electron microscope autoradiography)

2981-2985 Giulio Levi and Maurizio Raiteri Modulation of y-aminobutyric acid transport in nerve endings: Role of extracellular y-aminobutyric acid and of cationic fluxes

(neurotransmitters/synaptosomes/transmitter release/transmitter amino acids/homoexchange)

2986-2990 Philippe Cochard, Menek Goldstein, and Ira B. Black Ontogenetic appearance and disappearance of tyrosine hydroxylase and catecholamines in the rat embryo (neural crest/

development/immunohistochemistry)

2991-2993 J. C. Gillin, J. S. Hong, H.-Y. T. Yang, and E. Costa [Met5]Enkephalin content in brain regions of rats treated with lithium (neostriatum/globus pallidus/mania/neuropeptides/

psychobiology)

2994-2998 P. R. Adams and B. Sakmann Decamethonium both opens and blocks endplate channels (endplate kinetics/partial agonist/local anesthetics/ion channel)

2999-3003 V. A. Chiappinelli and R. E. Zigmond a-Bungarotoxin blocks nicotinic transmission in the avian ciliary ganglion (nicotinic antagonist/ganglionic nicotinic receptor/

parasympathetic ganglia)

3004-3008 A. G. Yee, G. D. Fischbach, and M. J. Karnovsky Clusters of intramembranous particles on cultured myotubes at sites that are highly sensitive to acetylcholine (freeze-fracture/

fusion-arrested myoblasts/embryonic chick/acetylcholine receptors)

Correction

CELL BIOLOGY

3009 Anil B. Mukherjee, Sheldon Orloff, Jean DeB. Butler, Timothy Triche, Peter Lalley, and Joseph D. Schulman Entrapment of metaphase chromosomes into phospholipid vesicles (lipochromosomes): Carrier potential in gene transfer (gene

mapping/somatic cell genetics/liposomes/encapsulation)

vii

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Contents (Conttnued from page ix)

IMMUNOLOGY

2883-2887 Oscar Valbuena, Kenneth B. Marcu, Carlo M. Croce, Kay Huebner, Martin Weigert, and Robert P. Perry Chromosomal locations of mouse immunoglobtulin genes (chromosomes/molecular hybridization/mouse-human hybrid cells)

2888-2892 G. Fernandes, E. J. Yunis, M. Miranda, J. Smith, and R. A. Good Nutritional inhibition of genetically determined renal disease and autoimmunity with prolongation of life in kdkd mice (calories!

nephronophthisis/longevity/immunity/histopathology)

2893-2896 R. Christopher Butler, Alexander M. Abdelnoor, and Alois Nowotny Bone marrow colony-stimulating factor and tumor resistance-enhancing activity of postendotoxin mouse sera (TA3-Ha ascites

tumor/passive transfer/lipopolysaccharide/tumor-necrotizing factor/anti-tumor resistance)

2897-2901 R. A. Murgita, E. A. Goidl, S. Kontiainen, P. C. L. Beverley, and H. Wigzell Adult murine T cells activated in vitro by a-fetoprotein and naturally occurring T cells in newborn mice: Identity in function and

cell surface differentiation antigens (embryonic serum protein/immunoregulation/in vitro antibody synthesis/Ly phenotype)

2902-2904 Michael A. Gordon, J. John Cohen, and Irwin B. Wilson Muscarinic cholinergic receptors in murine lymphocytes: Demonstration by direct binding ([3H]quinuclidinyl benzilate/

acetylcholine receptors/atropine)

2905-2908 Ursula Storb Direct demonstration of immunoglobulin K chain RNA in thymus T cells by in situ hybridization (T and B cells/complementary

DNA)

2909-2913 B. M. Ewenstein, T. Nisizawa, H. Uehara, S. G. Nathenson, J. E. Coligan, and T. J. Kindt Primary structure of murine major histocompatibility complex alloantigens: Isolation, biochemical characterization, and

preliminary alignment of CNBr fragments from the H-2Kb glycoprotein (histocompatibility antigens/radiolabeling/ immunoprecipitation)

2914-2917 Thomas J. Kipps, Baruj Benacerraf, and Martin E. Dorf Regulation of antibody heterogeneity by suppressor T cells: Diminishing suppressor T cell activity increases the number of

dinitrophenyl clones in mice immunized with dinitrophenyl-poly(Glu,Lys,Phe) or dinitrophenyl-poly(Glu,Lys,Ala) (immune suppression/antibody spectrotypes/Ir genes)

MEDICAL SCIENCES

2918-2922 Victor J. Stevens, Carol A. Rouzer, Vincent M. Monnier, and Anthony Cerami Diabetic cataract formation: Potential role of glycosylation of lens crystallins (nonenzymatic glycosylation/sul/hydryl oxidation)

2923-2927 John W. Holaday, Eddie Wei, Horace H. Loh, and Choh Hao Li Endorphins may function in heat adaptation (thermoregulation/hypophysectomylnaloxone/heat)

2928-2932 Paul Weisz-Carrington, Maria E. Roux, Michael McWilliams, Julia M. Phillips-Quagliata, and Michael E. Lamm Hormonal induction of the secretory immune system in the mammary gland (lymphocyte homing/IgA/lactation/gut-associated

lymphoid tissue)

2933-2936 Yair Reisner, Lea Itzicovitch, Asher MVeshorer, and Nathan Sharon Hemopoietic stem cell transplantation using mouse bone marrow and spleen cells fractionated by lectins (peanut agglutinin/

soybean agglutinin/graft-versus-.host reaction/spleen colony-forming units)

2937-2940 J. DeSimone, S. I. Biel, and P. Heller Stimulation of fetal hemoglobin synthesis in baboons by hemolysis and hypoxia (Hb F regulation/phenylhydrazine/hypobaric

chamber/erythropoietin)

2941-2944 Burton M. Altura and Simon Halevy Beneficial and detrimental actions of histamine H1- and H2-receptor antagonists in circulatory shock (hemorrhage/trauma/

antihistamines/pathophysiology of shock)

2945-2949 Robert C. Siegel, Katherine H. Chen, John S. Greenspan, and June M. Aguiar Biochemical and immunochemical study of lysyl oxidase in experimental hepatic fibrosis in the rat (collagen crosslinking/

biosynthesis of collagen/carbon tetrachloride-induced liver injury)

2950-2954 Anthony S. Liotta, Toshihiro Suda, and Dorothy T. Krieger f-Lipotropin is the major opioid-like peptide of human pituitary and rat pars distalis: Lack of significant f-endorphin (plasma

endorphin/corticotropin/opiates/radioimmunoassay)

2955-2958 Lesley Kaplan, Jerrold Weiss, and Peter Elsbach Low concentrations of indomethacin inhibit phospholipase A2 of rabbit polymorphonuclear leukocytes (inflammation/

prostaglandin synthesis)

2959-2963 Carl R. Alving, Edgar A. Steck, Willie L. Chapman, Jr., Virginia B. Waits, Larry D. Hendricks, Glenn M. Swartz, Jr., and William L. Hanson

Therapy of leishmaniasis: Superior efficacies of liposome-encapsulated drugs (antimonial compounds/phospholipids/model membranes/parasites )

MICROBIOLOGY

2964-2968 Douglas V. Faller, Jean Rommelaere, and Nancy Hopkins Large Ti oligonucleotides of Moloney leukemia virus missing in an env gene recombinant, HIX, are present on an intracellular 21S

Moloney viral RNA species (spliced gp7O mRNA)

(Continued on palge vii)

viii

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Contents (Continued from page x)

2790-2794 Ryu-ichiro Hata and Harold C. Slavkin De novo induction of a gene product during heterologous epithelial-mesenchymal interactions in vitro (induction of collagen

types/in vitro chondrogenesis)

2795-2799 Masaaki Terada, Elliot Epner, Uri Nudel, Jane Salmon, Eitan Fibach, Richard A. Rifkind, and Paul A. Marks Induction of murine erythroleukemia differentiation by actinomycin D (Friend cells/DNA/globin)

2800-2804 Michael Field, Lloyd H. Graf, Jr., Walter J. Laird, and Philip L. Smith Heat-stable enterotoxin of Escherichia coli: In vitro effects on guanylate cyclase activity, cyclic GMP concentration, and ion

transport in small intestine (cyclic AMP/secretion/absorption)

2805-2809 Marn C. S. Armelin and Hugo A. Armelin Steroid hormones mediate reversible phenotypic transition between transformed and untransformed states in mouse fibroblasts

(growth control/regulatory mutant/steroid hormone/tumorigenicity in nude mice)

2810-2814 Arthur Vogel, Elaine Raines, Beverly Kariya, Mary-Jane Rivest, and Russell Ross Coordinate control of 3T3 cell proliferation by platelet-derived growth factor and plasma components (growth control/serum/cell

cycle/cell culture)

2815-2819 Kenneth C. Joseph, Seung U. Kim, Anna Stieber, and Nicholas K. Gonatas Endocytosis of cholera toxin into neuronal GERL (neurons/Golgi)

2820-2824 Beverly A. Rubik and D. E. Koshland, Jr. Potentiation, desensitization, and inversion of response in bacterial sensing of chemical stimuli (chemotaxis/Salmonella

typhimurium/sensory transduction)

2825-2828 E. Beutler, E. Guinto, W. Kuhl, and F. Matsumoto Existence of only a single functional pool of adenosine triphosphate in human erythrocytes (red cell/metabolism/membrane)

2829-2833 M. Boublik and W. Hellmann Comparison of Artemia salina and Escherichia coli ribosome structure by electron microscopy (eukaryotic-prokaryotic ribosome/

structural similarity)

2834-2838 Beatrice Mintz, Claire Cronmiller, and R. Philip Custer Somatic cell origin of teratocarcinomas (embryonal carcinoma stem cells/postimplantation mouse embryos/W-mutation/

steel-mutation/parthenogenesis)

2839--2843 W. J. Pledger, C. D. Stiles, HL N. Antoniades, and C. D. Scher An ordered sequence of events is required before BALB/c-3T3 cells become committed to DNA synthesis (transition probability/

growth arrest points/platelets/plasma)

2844-2848 L. J. Wysocki and V. L. Sato "Panning" for lymphocytes: A method for cell selection (antibodies/plastic dishes/cell separation)

3009 Anil B. Mukherjee, Sheldon Orloff, Jean DeB. Butler, Timothy Triche, Peter Lalley, and Joseph D. Schulman Entrapment of metaphase chromosomes into phospholipid vesicles (lipochromosomes): Carrier potential in gene transfer

(Correction) (gene mapping/somatic cell genetics/liposomes/encapsulation)

DEVELOPMENTAL BIOLOGY

2849-2853 Donald D. Brown and J. B. Gurdon Cloned single repeating units of 5S DNA direct accurate transcription of 5S RNA when injected into Xenopus oocytes (purified

genes/recombinant DNA/living oocytes/nuclear injection)

ECOLOGY

2854-2858 P. R. Grant Dispersal in relation to carrying capacity (voles/presaturation dispersal/nutrient concentrations/habitat shifts/herbivore

limitation)

EVOLUTION

2859-2863 David L. Thurlow and Robert A. Zimmermann Conservation of ribosomal protein binding sites in prokaryotic 16S RNAs (ribosomal RNA/RNA-protein interaction/RNase

digestion/molecular evolution)

GENETICS

2864-2867 Robert Langenbach, Heather J. Freed, and Eliezer Huberman Liver cell-mediated mutagenesis of mammalian cells by liver carcinogens (hepatocytes/Chinese hamster cells/ouabain resistance/

nitrosamines/aflatoxins)

2868-2872 Motoo Kimura and - Tomoko Ohta Stepwise mutation model and distribution of allelic frequencies in a finite population (population genetics/frequency distribution/

electrophoretically detectable allele)

2873-2877 R. Michael Liskay and David M. Prescott Genetic analysis of the Gi period: Isolation of mutants (or variants) with a Gi period from a Chinese hamster ce?ll line lacking Gi

(cell cycle/V79 cells/somatic cell genetics/complement ation)

2878-2882 James F. Hopper, James R. Broach, and Lucy B. Rowe Rtegulation of the galactose pathway in Saccharomyces cerevisiae: Induction of uridyl transferase mRNA and dependency on

GAL4 gene function (in vitro translation/immunoprecipitation/GAL gene clust er/positive regulatio)n) * ~~~~~~~~~~~~~~~(Conrtinued on page tili)

1X

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Contents (Continued from inside back cover)

2699-2702 Robert V. Hageman and R. H. Burris Nitrogenase and nitrogenase reductase associate and dissociate with each catalytic cycle (nitrogen fixation/hydrogen evolution lag

phase/ATP hydrolysis)

2703-2707 Gary Wiesehahn and John E. Hearst DNA unwinding induced by photoaddition of psoralen derivatives and determination of dark-binding equilibrium constants by gel

electrophoresis (nicking-closing enzyme/ethidium bromide unwinding angle/agarose)

2708-2712 Eric Hunter, Ajit S. Bhown, and J. Claude Bennett Amino-terminal amino acid sequence of the major structural polypeptides of avian retroviruses: Sequence homology between

reticuloendotheliosis virus p30 and p30s of mammalian retroviruses (avian sarcoma virus/radioimmunoassay)

2713-2716 Cesar de Haro and Severo Ochoa Mode of action of the hemin-controlled inhibitor of protein synthesis: Studies with factors from rabbit reticulocytes (protein

phosphorylation/initiation factor eIF-2 kinase/initiation factor eIF-2 stimulating protein/ternary complex formation/40S complex formation)

2717-2721 Ronald L. Seale Nucleosomes associated with newly replicatedl DNA have an altered conformation (chromatin replication/nuclease digestion/in

vitro DNA synthesis)

2722-2726 John R. Bell, Michael W. Hunkapiller, Leroy E. Hood, and James H. Strauss Amino-terminal sequence analysis of the structural proteins of Sindbis virus (membrane glycoproteins/togaviruses/

microsequencing)

2727-2731 Olga 0. Blumenfeld and Anthony M. Adamany Structural polymorphism within the amino-terminal region of MM, NN, and MN glycoproteins (glycophorins) of the human

erythrocyte membrane (MN antigens/CNBr peptides)

2732-2736 John K. Rose, Hans Trachsel, Kahan Leong, and David Baltimore Inhibition of translation by poliovirus: Inactivation of a specific initiation factor (translational control/eukaryotic initiation

factor-4B/in vitro translation/vesicular stomatitis virus)

2737-2740 M. J. Gething, J. M. White, and M. L). Waterfield Purification of the fusion protein of Sendai virus: Analysis of the NH2-terminal sequence generated during precursor activation

(activation of infectivity/influenza hemagglutinin/hydrophobic amino terminus)

2741-2745 John J. Dunn, Elizabeth Buzash-Pollert, and F. William Studier Mutations of bacteriophage T7 that affect initiation of synthesis of the gene 0.3 protein (mRNA-rRNA interaction/Shine-

Dalgarno model/initiator AUG/RNA sequence analysis/ribosome binding)

2746-2749 Stephanie Broome and Walter Gilbert Immunological screening method to detect specific translation products (solid-phase radioimmunodetection/bacterial colonies/

phage X/autoradiography/l3-galactosidase)

2750-2754 Donald A. McClain, Patricia F. Maness, and Gerald M. Edelman Assay for early cytoplasmic effects of the src gene product of Rous sarcoma virus (microfilaments/microinjection/growth control/

surface modulating assembly/actin immunofluorescence)

BIOPHYSICS

2755-2758 Roger Cerf Molecular field theory of reversible unfolding of biopolymers (nucleic acids/proteins/cooperativity/absorbance/specific heat)

2759-2763 Barton A. Smith and Harden M. McConnell Determination of molecular motion in membranes using periodic pattern photobleaching (lipid bilayer/diffusion/fluorescence/

photobleaching recovery)

2764-2766 Deirdre Furlong Direct evidence for 6-fold symmetry of the herpesvirus hexon capsomere (scanning transmission electron microscopy)

CELL BIOLOGY

2767-2771 Michael M. Gottesman Transformation-dependent secretion of a low molecular weight protein by murine fibroblasts (major excreted polypeptide/

tumorigenicity/anchorage independence/radiolabeling/immunofluorescence)

2772-2775 M. Laburthe, M. Rousset, C. Boissard, G. Chevalier, A. Zweibaum, and G. Rosselin Vasoactive intestinal peptide: A potent stimulator of adenosine 3':5'-cyclic monophosphate accumulation in gut carcinoma cell

lines in culture (hormone action/receptor/prostaglandin/catecholamine/malignant digestive cell)

2776-2780 Richard D. Nathan and Robert L. De.HIaan In vitro differentiation of a fast Na+ conducta.nce in embryonic heart cell aggregates (electrophysiology/voltage clamp/tissue

culture/ionic currents/protein synthesis)

2781-2784 James H. Clark, James W. Hardin, Helen A. Padykula, and Constance A. Cardasis Role of estrogen receptor binding and transcriptional activity in the stimulation of hyperestrogenism and nuclear bodies (nuclear

morpho logy/na fox id ine/estrad iol )

2785-2789 Richard G. Woodbury, Gregory M. Gruzenski, and David Lagunoff Immunofluorescent localization of a serine protease in rat small intestine (group-specific protease/intracellular protease/atypical

mast cell)

(Conltinued on poge ix)

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