Go get papers from return tray!

**Make up tests!**

Please get notes sheet from side

NO SCHOOL THURS OR FRIDAY!

Objectives for Today: Explain why cells divide.

THE CELLULAR BASIS THE CELLULAR BASIS OF INHERITANCEOF INHERITANCE

CHAPTER 9

Why Is Cell ReproductionEssential for Life?

#1) Maintain/Heal the Body

– TO REPLACE LOST OR DAMAGED CELLSExample:Every minute of the day we lose

about 30,000 to 40,000 dead skin cells off the surface of our skin.

Why Is Cell Reproduction Essential for Life?

#2) GROWTH - Increase body size by

increasing the number of cells in the body

Your cells can only get so big. Why?

Why Is Cell Reproduction Essential for Life?

#3) REPRODUCTION = TO CREATE A COMPLETE NEW ORGANISM.

2 TYPES OF REPRODUCTION:a) ASEXUALb) SEXUAL

ASEXUAL REPRODUCTION• SINGLE PARENT• OFFSPRING ARE

GENETICALLY IDENTICAL TO EACH OTHER AND TO PARENT.

• SEEN IN UNICELLULAR ORGANISMS AND SOME MULTICELLULAR ORGANISMS SUCH AS PLANTS,FUNGI, AND SOME ANIMALS LIKE SPONGES AND STARFISH.

How Many Parents?

SEXUAL REPRODUCTION• 2 PARENTS• GENETIC MATERIAL

(CARRIED IN EGG AND SPERM) FROM EACH PARENT COMBINES

• EACH OFFSPRING IS GENETICALLY DIFFERENT FROM PARENTS

• Egg and Sperm are produced through

cell division

REVIEW:WHY DO CELLS DIVIDE

AND PRODUCE NEW CELLS?

For Maintenance of the body(multicellular organisms)

For Growth (multicellular organisms)

For Reproduction(multi- and unicellular organisms)

Assignments:

Read Section 9.1 (pgs 180-181) Answer guided reading questions.

Vocabulary for 9.4

Quiz on Wednesday! Quiz on Wednesday!

Objectives for today:Explain and Describe the Cell Cycle

Please get out your homework from last night.

QUIZ TOMORROW: Vocab and Why cell’s divide notes/reading

Videos

• Robert Wadlow Jr. World’s Tallest Man~! http://www.youtube.com/watch?v=7N4bg1btzY4

• Skin Gun http://www.youtube.com/watch?v=eXO_ApjKPaI

The“CELL CYCLE”

•STARTS WHEN A CELL IS “BORN” & ENDS WHEN IT REPRODUCES.

•CELL CYCLE PRODUCES CELLS NEEDED FOR GROWTH & MAINTENANCE OF THE BODY

The“CELL CYCLE”

Cell is notCell is notdividingdividing(Most of the time)

Cell isCell isdividingdividing

NucleusNucleusdivides divides

firstfirst

CytoplasmCytoplasmdivides divides

lastlast

The“CELL CYCLE”

• HAS 2 MAIN STAGES: •INTERPHASE

– cell isn’t dividing

•MITOTIC PHASE– cell is dividing

INTERPHASE

•WHAT IS IT?

•WHAT HAPPENS DURING IT?

INTERPHASE

• LONGEST STAGE (90% OF THE CELL CYCLE)

• THE CELL GROWS & PERFORMS ITS JOB AS A CELL

INTERPHASE• IN THIS STAGE

DNA EXISTS AS A MASS OF VERY LONG THIN FIBERS CALLED

_________________.CHROMATIN

INTERPHASE• CELL ALSO PREPARES

TO REPRODUCE (CELL DIVISION) BY INCREASING ITS NUMBER OF ORGANELLES & BY MAKING COPIES OF ALL MAKING COPIES OF ALL ITS _____________ITS _____________.

muy importante!!!

•EACH DNA STRAND IS COPIED & THE 2 COPIES ARE JOINED AT ONE SPOT CALLED THE __________________.

DNA

CENTROMERE

DNA IN CHROMATIN FORM

What Happens Next?!

•After the cell has made all its preparations, then it divides!

•On to the Mitotic Phase!!

MITOTIC PHASE

• SHORTEST STAGE of the CELL CYCLE

• THIS IS WHERE 11 CELL DIVIDES INTO 2 2 CELLSCELLS

• OCCURS IN 2 STEPS:

1) MITOSIS2) CYTOKINESIS

MITOSIS• All about the

Nucleus!

• In this stage the nucleus divides into 2 and the chromosomes are evenly divided up.• Each daughter nucleus

receives a complete set of chromosomes

MITOSIS• ALL THE DUPLICATED

CHROMATIN FIBERS NOW COIL UP (GET SHORTER & THICKER) & ARE CALLED

____________________.• EACH CHROMOSOME

IS MADE UP OF 2 IDENTICAL HALVES CALLED ______________

.

SISTERCHROMATIDS

CHROMOSOMES

SISTER CHROMATIDS

MITOSIS

• The SISTER CHROMATIDS SEPARATE & GO TO OPPOSITE ENDS OF THE CELL FORMING 2 NEW “DAUGHTER” NUCLEI

CYTOKINESIS• The CYTOPLASM

DIVIDES BETWEEN THE 2 NEW “DAUGHTER” NUCLEI FORMING 2 NEW CELLS

The“CELL CYCLE”

Cell is notCell is notdividingdividing(Most of the time)

Cell isCell isdividingdividing

NucleusNucleusdivides divides

firstfirst

CytoplasmCytoplasmdivides divides

lastlast

INTERPHASEINTERPHASE

MITOTICMITOTICPHASEPHASE

MITOSISMITOSIS CYTO-CYTO-KINESISKINESIS

Name the Structure!

??

?

Chromosomes

?

?

Centromere

Centromere

??

SISTERCHROMATIDS

Homework tonight: Study for Quiz

2nd and 3rd hour—You will be testing Thursday!

Mitosis Quiz Friday!

Pass back Cell Respiration Quests

Objectives for today:

Trace the path of the cell cycle!

______________ =series of events that cells go through as they grow and develop

CELL CYCLE

CELL CYCLEINTERPHASE – non-dividing phase G1- Grow bigger

Cell is “doing its job” DNA is spread out as

chromatin

S - Synthesis (copy DNA)& chromosomal proteins

G2- Grow bigger, make organelles &

molecules needed for cell division

CELL DIVISIONMITOSIS – Nuclear division Prophase Metaphase

AnaphaseTelophaseCytokinesis – Cytoplasm divides

G0 – cell stops dividing (Ex: nerve cell)

INTERPHASE (G1 - S - G2)

In between divisionsCells are in this phase most of the timeCan see nucleus DNA spread out as chromatin

Can’t see chromosomes DNA gets copied (S)

Cell gets ready to divide

PROPHASE1st dividing phase

Spindle fibers form & attach to chromosomes

Nuclear membrane & nucleolus disappear

DNA scrunches into chromosomes

Centrioles appear in centrosome region & move to poles

Pearson Education Inc publishing as Pearson Prentice Hall

http://www.life.uiuc.edu/plantbio/102/lectures/08mit&veg102.html

________ region organizes spindle

Spindle MICROTUBULES are part of cytoskeletonhttp://www.coleharbourhigh.ednet.ns.ca/library/organelle_worksheet.htm

CENTROSOME

METAPHASE

Chromosomes line up in ___________middle

Images from:Pearson Eduction Ince; Publishing as Pearson Prentice Hall http://www.science.siu.edu/plant-biology/PLB117/JPEGs%20CD/0247.JPG

ANAPHASECentromeres splitCentrioles pull chromatids_______apart

Images from:Pearson Eduction Ince; Publishing as Pearson Prentice Hall http://www.science.siu.edu/plant-biology/PLB117/JPEGs%20CD/0247.JPG

TELOPHASE (reverse prophase steps)

See ______ nuclei

Nuclear membrane & nucleolus returnChromosomes spread out as chromatinCentrioles disappear

Spindle fibers disappear

two

Images from:Pearson Eduction Ince; Publishing as Pearson Prentice Hallhttp://www2.bc.cc.ca.us/cnewton/Biology%2011/Mitosis.html

CYTOKINESISCytoplasm splits into 2 cells

ANIMAL CELLS pinch cytoplasm in two with a ______________________CLEAVAGE FURROW

CYTOKINESISCytoplasm splits into 2 cellsPLANT CELLS can’t pinch because they have a sturdy ____________

Plant cells separate cytoplasm by growing a _______________ down the middle.

CELL PLATE

CELL WALL

http://www.eastcentral.edu/acad/depts/BI/plant_mitosis_nolabels.html

Centrioles

Chromatin

Interphase

Nuclear envelope

Cytokinesis

Nuclear envelope reforming

Telophase

Anaphase

Individual chromosomes

Metaphase

Centriole

Spindle

CentrioleChromosomes

(paired chromatids)

Prophase

Centromere

Spindle forming

Section 10-2

Centrioles

Chromatin

Interphase

Nuclear envelope

Cytokinesis

Nuclear envelope reforming

Telophase

Anaphase

Individual chromosomes

Metaphase

Centriole

Spindle

CentrioleChromosomes

(paired chromatids)

Prophase

Centromere

Spindle forming

Section 10-2

Centrioles

Chromatin

Interphase

Nuclear envelope

Cytokinesis

Nuclear envelope reforming

Telophase

Anaphase

Individual chromosomes

Metaphase

Centriole

Spindle

CentrioleChromosomes

(paired chromatids)

Prophase

Centromere

Spindle forming

Section 10-2

Centrioles

Chromatin

Interphase

Nuclear envelope

Cytokinesis

Nuclear envelope reforming

Telophase

Anaphase

Individual chromosomes

Metaphase

Centriole

Spindle

CentrioleChromosomes

(paired chromatids)

Prophase

Centromere

Spindle forming

Section 10-2

Centrioles

Chromatin

Interphase

Nuclear envelope

Cytokinesis

Nuclear envelope reforming

Telophase

Anaphase

Individual chromosomes

Metaphase

Centriole

Spindle

CentrioleChromosomes

(paired chromatids)

Prophase

Centromere

Spindle forming

Section 10-2

Centrioles

Chromatin

Interphase

Nuclear envelope

Cytokinesis

Nuclear envelope reforming

Telophase

Anaphase

Individual chromosomes

Metaphase

Centriole

Spindle

CentrioleChromosomes

(paired chromatids)

Prophase

Centromere

Spindle forming

Section 10-2

• Cell Cycle Flip Book …

Due end of class tomorrow! You will have the hour to complete it!

Mitosis Quiz Friday!

2nd hour: Turn in your flip-books to basket with your rubric (does not need to be attached)

Objective for TodayObjective for Today:

Vocab Quiz –after quiz sit quietly

and wait for directions.

Analyze the cell cycle with a partner.

CELL CYCLE QUIZ TUESDAY!!!!

11/19/2012

Objectives for TodayObjectives for Today:

Sock-a-some Activity

Cell Cycle Packet from Friday is homework! –Good review!

CELL CYCLE QUIZ TUESDAY!!!!

Rube-GoldBerg Weds

NO SCHOOL THURS—TURKEY!!!

NO SCHOOL FRI- SHOPPING???

11/26/2012

Bell Ringer:

Get out a sheet of paper: (Answer these questions)

•Explain what you know about cancer?

•Have you been effected by cancer?

How?

Faces of Cancer

• You are going to work as teams.• Each one of you will become a different

person.• You will each discuss your life and how

you got cancer.

• It is important that you DO NOT work ahead. You need to work with your group.

Get out your handouts from yesterday. We are going to discuss!

Read over your answers.

Be ready to discuss, you never know who I am going to call on

Let’s Discuss Yesterday…

• Conclusions:– 1. Family History– 2. Relationship Between Cancer and Age– 3. Types of Cancer– 4. Possible Risk Factors

Did anyone notice a black dot on one of their pieces of paper??

Shaun O’MalleyI was born of Irish-American parents in 1936 in western Pennsylvania. My dad worked in the steel mills, and my

mom ran a little coffee shop. Both my parents had skin cancer before they were 60.

0–19 yearsI was a good student in school but always preferred to

be outdoors rather than cooped up inside doing homework. I loved any type of sports, especially

baseball. When I was in high school, I started work ing on a construction crew in the summer.

Because of my fair skin, I got lots of bad sunburns, but I didn’t really care.

•

20–39 yearsI continued working in construction after I finished high

school. Soon I was a foreman and making enough money to get married. My wife and I both enjoyed socializing; on Friday nights, I especially enjoyed hanging out in the local bar where I would play darts and watch TV.

We had two kids, both with fair skin and freckles, just like their dad.

40–59 yearsI started gaining weight when I was in my 40s, not bad, but a

little, and my wife started nagging me about seeing a doctor. When I was 45, to make the wife happy, I finally went for a check-up. All the doc- tor found was that my blood pressure was a little high. She gave me medication for that and cau tioned me to continue getting my exercise.

When I was 57, my wife started nagging me again, this time about some moles and freckles on my neck and shoulders that she thought were suspicious looking. I went back to the doctor again, but this

time, she referred me to a dermatologist. Sure enough, my wife was right: Several of them were cancerous and had to be removed.

60+ yearsNow that I understand about skin cancer, I go for

regular check-ups. So far, I haven’t had another problem, but I’m not taking any chances. I also have started nagging my children about wearing sun- screen and about seeing that their children do too.

Paul AshlandI was born in 1924 in northern Michigan of African-American parents. My older sister had lung

cancer when she was in her 60s, but she was a smoker, so we weren’t surprised.

0–19 yearsWe had a normal childhood: My father worked,

and my mother stayed home to watch the kids. We ate well—my father especially loved steak and baked potatoes for dinner—but I wasn’t overweight because I was active in sports. I started chewing a little when I was 18 (I also started drinking a little— all the guys did it).

20–39 yearsAfter I finished high school, I got a good job with a

trucking company and started making long-distance hauls with a partner. I was on the road a

lot, so I didn’t really develop any hobbies or outside inter ests. We traveled five days out of seven, and

slept and ate on the road. Chewing helped me keep awake on long hauls.

•40–59 yearsBy the time I was in my mid-40s, I started

gaining weight. When I developed headaches, I went to the doctor to see what was wrong. He said I had high blood pressure, but said I could control it with diet if I tried to. I lost some weight on the diet he pre- scribed, and the headaches went away. I’m usually pretty good about sticking to the diet, though I do like a drink or two after a long day on the road.

60+ yearsI retired when I was 65. Retirement was hard on me: I was used

to traveling and didn’t really have friends except for other truckers. To ease my loneli ness, I hung out at the terminal and helped load and unload the trucks just for the heck of it.

When I was about 69, I noticed soreness in my mouth and saw something that looked like a large canker sore. I figured it would go away. It didn’t. Then I noticed a lump underneath it. It was pretty sore, so I decided to see a doctor. She took a biopsy and found that I had throat cancer. The surgery was tough, and I don’t look the same. I don’t go out much now, even to the docks. My mouth is dry and sore all the time from the radia tion. Between that and the chemotherapy, I really can’t eat much and don’t taste what I do eat. I con tinue to lose weight and feel bad most of the time. I really miss seeing the guys from the docks.

Paul died at age 71 of cancer. Twelve of his bud- dies from the trucking company attended his funeral.

Discussion Questions:

1. In this activity, all students in the class assumed the role of someone who developed cancer sometime in his or her lifetime. Is this an accurate representation of the risk of cancer among the American population?

2. What explanation can you offer for the observation you made about the incidence of cancer compared with age?

3. What is the most interesting or surprising thing you learned from this activity? What was the most important? Why?

• http://www.youtube.com/watch?v=trqht9pZdgk

Regulating the Cell cycleA. Cyclins- proteins regulate the timing of the

cell cycle

1.) Internal regulators: ex-won’t let cell enter mitosis until all the chrom. are copied

2.) External regulators: respond to events outside the cell- speed up or slow down the cell cycle

ex: growth factors-stimulate growth in embryo development or wound healing

B. Cells sometimes do not respond to cell cycle regulators-form tumors or cancer -cells keep dividing when they shouldn’t.

1. Benign- noncancerous growth, doesn’t spread-usually remove

2. Malignant- cancerous growth – can spread throughout body

a. cancer cells invade and destroy neighboring cells

3. All cancer is caused by cells losing control over the cell cycle

c. Stem cells

1. unspecialized cells capable of renewing themselves through cell division, sometimes after long periods of inactivity

a. embryonic stem cells or adult stem cells

2. Under certain conditions, they can be induced to become tissue- or organ-specific cells with special functions

ex: scientists can use undifferentiated stem cells to grow other types of cells nerve, muscle, heart, etc.

Homework: Read Pages 190-191 in your book.

Answer questions 1-3 on page 190.

TEST FRIDAY! --You will get study guides tomorrow! I will post a copy online, so if you are absent tomorrow, check online!