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Hessian Ministry of Economics, Transport, Urban and Regional Development www.hessen-biotech.de BIO International Convention 2013 Hessen: Biotech-Excellence “Made in Germany”
Hessian Ministry of Economics,
Transport, Urban and Regional Development
www.hessen-biotech.de
BIO International Convention 2013Hessen: Biotech-Excellence “Made in Germany”
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Hessen features a central position in Germany and Europe, both geographically
and economically. It has the strongest economy of and the highest labor productivity
in Germany, making it the leading federal state with a gross domestic product by
workforce of around 70,600 Euros.
Hessen’s economic heart beats in the Rhine Main area. Over 70 percent of gross value
creation is generated in the greater Frankfurt area. As a hub for transportation, a con-
vention location, and a financial center, Frankfurt is one of the top ten leading econo-
mic regions worldwide.
Hessen is also known for its high quality of life, attracting companies and work force
from all over the world. People from more than 190 nations contribute to its cultural
variety, cosmopolitan outlook, and vibrant day to day living and shared activities in
education, work and leisure.
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Pharmaceutical & Chemical Industry:
Facts & Figures
Hessen-Biotech:
Hub for Innovative Companies
CIB Frankfurt:
German Network for Industrial Biotech
Ci3:
Cluster for Individualized ImmunIntervention
FIZ Frankfurt: Frankfurt Biotechnology
Innovation Center
Summary of Economic Data
"Good Reasons for Hessen"
Table of contents
Europe
European Union
Germany
Hessen
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Biotechnology in Hessen:
• 225 biotech companies (59 core biotechs)
• EURO 5,2 billion in revenues
• 40% of Hessen’s biotech companies are SMEs
with less than 10 employees
• leading location for biotech patents in Germany
(non-city states)
Pharmaceutical & Chemical Industry:
• 180 companies with 58,422 employees
• EURO 24,5 billion in revenues
• largest location of biotech manufacturing in Germany
Medical Technology Industry:
• 1,100 companies with 20,000 employees
• EURO 4 billion in revenues
• 13,4% of expenditures in R&D
DID YOU KNOW?
• that Hessen is one of the most important
investment locations for foreign enter-
prise in Germany? More than 950 US-
American, over 250 Indian and 300
Chinese companies have their headquar-
ters here. More than 200 companies are
each represented from both Japan and
Korea.
• that major foreign companies are
located in Hessen: ABB, Amazon, Dunlop,
General Motors, Nestlé, Nikon, Procter &
Gamble, Sanofi Aventis, Novartis, etc.
5Kassel
Marburg
FuldaGießen
Frankfurt
Hanau
Darmstadt
Wiesbaden
HessenRegional distribution of biotechnology companies in Hessen.
Germany
DID YOU KNOW?
• that there is a superb facility at the
University Clinic in Frankfurt for the
acceleration of the development of inno-
vative medicines?
The Center for Medication Research,
Development and Safety (ZAFES) brings
the knowledge from universities, the
pharmaceuticals industry and biotechno-
logy together under one roof.
• that Hessen is the leading location for
international communities? A dense
network of communities from abroad
exists here, with international schools
and kindergartens, clubs, restaurants,
and shops.
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Hessen-Biotech coordinates the activities of the Hessian Ministry of Econo-
mics for the funding of biotechnology enterprises. It is the platform for infor-
mation, communication and cooperation in biotechnology.
Hessen-Biotech:
Offers up-to-date industry information: Publishing studies, information from
industry experts and the quarterly publication “Hessen-Biotech NEWS” and
Hessen’s online biotech industry directory “Competence Atlas Hessen-Biotech”.
Connects and advises biotechnology companies: Facilitate information ex-
change between Hessen’s companies, colleges, universities and research
institutions.
Is a communication platform: Organizing cooperative booths at international
trade fairs as well as symposiums, workshops and congresses on current bio-
technology discussion topics. Hessen-Biotech is administered and managed
by the Hessen Trade & Invest GmbH.
Hessen-Biotech
Address: Hessen Trade & Invest GmbH
Konradinerallee 9
65189 Wiesbaden
Germany
Contact Name: Dr. Thomas Niemann
Contact Phone: +49 (0)611 95017 8646
Contact Fax: +49 (0)611 95017 58646
Contact Email: [email protected]
Website: www.hessen-biotech.com
German State of Hessen
U.S. Office for Economic Development
Ms Kristina L. Garcia
+1 212 7035566
DID YOU KNOW?
• as a national Cluster for Industrial
Biotechnology CIB initiated projects
between Universities, Research Organisa-
tions and large companies such as
BASF AG, DSM Nutritional Products,
Merck KGaA, Symrise AG and Sanofi
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Address: Hessen Trade & Invest GmbH
Konradinerallee 9
65189 Wiesbaden
Germany
Contact Name: Ms Dolores Schmitt
Contact Phone: +49 (0)611 95017 8312
Contact Fax: +49 (0)611 95017 58312
Contact Email: [email protected]
Website: www.cib-frankfurt.de
The Frankfurt Bioindustry Cluster CIB pursues the aim of promoting close
networks and synergies between all actors in the Industrial Biotechnology
value creation chain in Germany.
CIB Frankfurt
• networks companies, scientists and investors
• initiates innovative Industrial Biotechnology projects
• ensures financing for Industrial Biotechnology companies
• arranges participation in suitable funding programs
CIB Frankfurt
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In healthcare, a paradigm shift is under way towards more patient-centered indi-
vidualized treatment approaches. Personalized medicine offers the opportunity
for a more effective, better tolerated and economic healthcare practice. Ci3 is
spearheading personalized medicine, by focusing on the use of the human im-
mune system for the treatment of life-threatening conditions such as cancer,
autoimmune diseases and infections. It is our vision to combine the outstan-
ding scientific excellence and commercial expertise of our cluster partners in
the Rhine-Main Metropolitan Region, to develop new immune intervention
strategies with large economic potential and to position Ci3 among the prime
immunology clusters in Europe. To turn our vision into reality, Ci3 has establis-
hed a network of more than 120 partners from industry, research, patient care
and government, along the entire innovation and value chain. Ci3 is a Leading-
Edge-Cluster funded by the German Federal Ministry of Education and
Research (BMBF) up to EURO 40 Million (plus the same amount from industry
partners) over a period of 5 years.
Cluster for Individalized ImmunIntervention Ci3
Address: Kupferbergterrasse 17-19
55116 Mainz
Germany
Contact Name: Dr. Rainer Wessel
Contact Phone: +49 (0)6131 62 305 81
Contact Email: [email protected]
Website: www.ci-3.de
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Major Companies
AbbVie Deutschland GmbH & Co. KG www.abbvie.de
Bayer Vital GmbH www.pharma.bayer.de
Biotest AG www.biotest.de
Dr. Falk Pharma GmbH www.drfalkpharma.de
Euroimmun AG www.euroimmun.de
Merck Serono GmbH www.merck.de
Miltenyi Biotec GmbH www.miltenyibiotec.com
Sanofi Aventis Deutschland GmbH www.sanofi.de
SME
BioNTech AG www.biontech.de
celsius 37.com AG www.celsius37.com
EUFETS GmbH www.eufets.com
GANYMED Pharmaceuticals AG www.ganymed-pharmaceuticals.com
Information Desire Software GmbH www.infodesire.com
InstrAction GmbH www.instraction.com
medesso GmbH www.medesso.de
Proteopath GmbH
Ribological GmbH www.ribological.de
Theracode GmbH www.theracode.de
thinXXS Microtechnology AG www.thinxxs.de
Tulip GmbH www.tulip-pharmaceuticals.de
UniCell GmbH
Zedira GmbH www.zedira.com
Research Institutes & Academic Organizations
CIMT www.cimt.eu
GRC Blood Donor Service gGmbH www.blutspende.de
Fraunhofer ITWM e.V. www.itwm.fraunhofer.de
Georg-Speyer-Haus www.georg-speyer-haus.de
IMB gGmbH www.imb-mainz.de
IMM gGmbH www.imm-mainz.de
Krankenhaus Nordwest GmbH www.krankenhaus-nordwest.de
MPI for Polymer Research www.mpip-mainz.mpg.de
Paul-Ehrlich-Institute www.pei.de
TRON gGmbH www.tron-mainz.de
TU Darmstadt www.tu-darmstadt.de
University Medical Center
Hamburg-Eppendorf www.uke.de/institute/tumorbiologie
Johannes Gutenberg University Mainz www.uni-mainz.de
University Medical Center
Goethe-University Frankfurt www.klinik.uni-frankfurt.de
University Medical Center
of the JGU Mainz www.unimedizin-mainz.de
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The FIZ Frankfurt Biotechnology Innovation Center, founded in 2002, is a market-
oriented technology center which offers small and medium-sized companies in
the life sciences sector a customized infrastructure for innovations with access
to collaborations, interdisciplinary networks and markets. Within the Science
City Frankfurt-Riedberg, the centrally located FIZ forms the bridge to the
economy and creates optimal working conditions for research, development,
networking and marketing. The FIZ has 15,000 sqm of laboratory and office
space with more than 350 highly specialized persons employed in the compa-
nies resident at FIZ. An additional 4,000 sqm of laboratory and office space will
be added in early 2013.
The companies in the FIZ benefit from the innovation infrastructure and
platform and additionally are provided access to potential partners and markets.
FIZ Frankfurter Innovationszentrum Biotechnologie GmbH
Founded 2002
Address: FIZ Frankfurter Innovationszentrum
Biotechnologie GmbH
Altenhöferallee 3
60438 Frankfurt am Main
Germany
Contact Name: Ms Lilliffer Seiler
Contact Phone: +49 (0)69 800865-0
Contact Fax: +49 (0)69 800865-19
Contact Email: [email protected]
Website: www.fiz-biotech.com
© FIZ Frankfurt
11Companies at FIZ Frankfurt Biotechnology Innovation Center
– Examples –
Merz
bio.logis
bio.logis is a clinical diagnostic genetics
unit and a genetic information company
with a unique combination of excellence
in medical science, laboratory operations
and the development of IT-systems for the manage ment of
biological and medical data.
bio.logis provides genetic counseling and genetic diagnos -
tics covering the full spectrum of medical human genetics.
Through its unique Personal Genomics Service (PGS)
bio.logis provides individuals with access to their personal
genome. PGS delivers actionable genetic information that
has been scientifically proven to enable better health- and
lifestyle-related decisions.
Year of foundation: 2008
Employees: 50
Merz is a speciality pharmaceutical com-
pany that focuses on innovative drugs for
neurology as well as on solutions for me-
dical and aesthetic dermatology.
Merz has a leading position in neurology and focuses its
R&D and business development activities on projects in
the area of movement disorders – in particular on projects
complementing Merz’ proprietary botulinum neurotoxin
franchise. Merz’ botulinum neurotoxin type A is appro-
ved in cervical dystonia, blepharospasm and post-stroke
spasticity of the upper limp. Furthermore it is used for
the treatment of glabellar frown lines. Merz’ aesthetics
portfolio is complemented by topical and injectable pro-
ducts.
Year of foundation: 1908
Employees: 2,400 worldwide
PPH plus
PPH plus provides operational and
consultancy services in clinical deve-
lopment programs to pharma, medi-
cal device and biotech companies from all over the world
(trials from phase I to IV). PPH plus ties all required ex-
pertise and skills together and assumes overall account -
ability for the execution of development projects and
programs contracted with us.
Year of foundation: 2004
Employees: 10
ViS Research Institute GmbH
The ViS platform is a game-changing
solution to the inefficiencies of clinical
trial planning. It puts comprehensive,
up-to-date analytics about all research centers at the fin-
gertips of trial planners, while allowing sites to easily
communicate their expertise through the ViS social net-
work. This open-access sharing of information leads to
faster and better trial planning at significantly lower cost.
ViS is a global enterprise, with regional hubs in New York,
São Paulo, Frankfurt and Mumbai.
Our partner in Frankfurt is PPH plus.
Year of foundation: 2010
Employees: 68
Evolvus
Evolvus offers cutting edge solu-
tions and services in major func -
tional areas of Drug Discovery
and Development.
Our dedicated facilities which are networked through
secure software comprise of more than 500 professional
chemists, software engineers, pharmacologists, molecu-
lar biologists, all of whom are specifically trained post-
graduates in the area of Medicinal Chemistry,
Discovery Informatics, Knowledge Management and
Clinical Data Management services.
Employees: > 500
GFE Blut
GFE Blut was founded in November
2005 by three Red Cross Blood
donation services, with the primary
goal to develop, manufacture and distribute instruments
and test kits for the detection of transfusion relevant viru-
ses in blood donations by Nucleic acids Amplification Tech-
nology (NAT).
GFE Blut’s autoX-System and reagent kits were CE-IVD
approved and entered routine testing in 2010.
We provide the complete range of products required to
perform NAT testing on blood donations; including, but
not limited to, fully automated sample processors, virus
detection assays and software for data analysis.
Year of foundation: 2005
Employees: 28
Octapharma
Octapharma is one of the largest
human protein manufacturers in the
world. Our core business is the de-
velopment, production and sale of premium protein pro-
ducts from human plasma and human cell-lines.
Octapharma, founded in 1983, employs more than 5,000
people in 28 countries with sales of approx. € 1 billion.
Patients in over 80 countries are treated with products in
the following therapeutic areas:
• Hematology (coagulation disorders)
• Immunotherapy (immune disorders)
• Intensive Care and Emergency Medicine
Octapharma owns five state of the art production facilities
in Austria, France, Ger-many, Sweden and Mexico.
Year of foundation: 1983
Employees: > 5000 worldwide
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Summary of economic data:
• 21,115 km² Area
• 3 government districts – Darmstadt, Giessen and Kassel
• 26 independent cities and counties
• 6,069,386 inhabitants
• 287 inhabitants per km²
• 670,000 inhabitants in Hessen’s largest city, Frankfurt am Main
• 221 billion Euros gross domestic product
• 36,380 Euros per-capita GDP
• 3,128,000 employed persons
Reasons for Hessen:
• Hessen – “The” Center of the European chemical & pharmaceutical industry
• 1,700 CRO research experts in Hessen
• Access to more than 500 million patients in 3h flight time
• Highly qualified and well-trained personnel
• Excellent professional regulatory environment
• Paul-Ehrlich-Institut (Agency of the German Federal Ministry of Health)
located in Langen, Hessen
• Center for Drug Research, Development and Safety (ZAFES)
Imprint
Publisher
Aktionslinie Hessen-Biotech
Dr. Thomas Niemann
Hessen Trade & Invest GmbH
Konradinerallee 9 | D-65189 Wiesbaden
Layout
Piva & Piva, Darmstadt
Photos
© Anyaivanova | Dreamstime.com (cover),
Andrey Kiselev | Dreamstime.com (p. 5),
Ci3 e.V. (p. 8)
This project is cofinanced by the European Union.
