Barbara MascialinoJuly 26th, 2004 INFN-Genova

Overview of the new phase of

Barbara Barbara MascialinoMascialino

July 26th 2004

Barbara MascialinoJuly 26th, 2004 INFN-Genova

Introduction• First PhaseFirst Phase already completed• Last March 19March 19thth started

the Second PhaseSecond Phase.

Its aim is to bring the requirements resulting

from the General StudyGeneral Study

into an operative phaseoperative phase,

developing a software software

systemsystem to fulfil them.

Barbara MascialinoJuly 26th, 2004 INFN-Genova

The simulation tool will

be usefuluseful for space

applications:

- - astronauts radioprotectionastronauts radioprotection,,

- - airlines pilots radioprotectionairlines pilots radioprotection, ,

- - human presence in the space.human presence in the space.HUMEX

a study on the survivability and adaptation of humans to

long-duration exploratory missions

Barbara MascialinoJuly 26th, 2004 INFN-Genova

Manyfold applications

The outcome of the

project would be relevant also for:• biological experimentsbiological experiments• radiotherapyradiotherapy• radiobiologyradiobiology• physicsphysics (micro and nano-dosimetric studies)

• technology transfertechnology transfer from the from the space environment to the societyspace environment to the society

Barbara MascialinoJuly 26th, 2004 INFN-Genova

Study plan

• 11: study of the project environmentproject environment• 22: creation of a

application prototypeapplication prototype• 33: development of the prototype and

related components into an articulated applicationapplication aimed at modelising the radiation effects at cellularcellular and DNADNA levels.

Barbara MascialinoJuly 26th, 2004 INFN-Genova

• United Software Development ProcessUnited Software Development Process– practical guidance and tools from the RUPRUP– mapping onto ISO 15504

• Incremental and iterative life cycle model The software will be

devolped through a series

of iterationsiterations, each one

visiting all the main software disciplines

Software process guidelines

SPIRAL APPROACHSPIRAL APPROACH

Barbara MascialinoJuly 26th, 2004 INFN-Genova

Deliverables

ESA PSS-05ESA PSS-05 software development standard:

- User Requirement DocumentUser Requirement Document- Software Specification DocumentSoftware Specification Document- Software User ManualSoftware User Manual- Software Validation and Verification PlanSoftware Validation and Verification Plan

Barbara MascialinoJuly 26th, 2004 INFN-Genova

Milestones

PHASE 1 MILESTONE 1 SCIENTIFIC SCIENTIFIC

BACKGROUNDBACKGROUND

PHASE 2 MILESTONE 2 USER USER REQUIREMENTS REQUIREMENTS DOCUMENTDOCUMENT

PHASE 3 MILESTONE 3 PROTOTYPEPROTOTYPE

PHASE 4 MILESTONE 4 SECOND ITERATIONSECOND ITERATION

PHASE 5 MILESTONE 5 THIRD ITERATIONTHIRD ITERATION

Barbara MascialinoJuly 26th, 2004 INFN-Genova

Milestone 1: September 19th 2004

Study of:- Space radiation environment- ESA space projects- Existing physics models- Radiation effects on macroscopic biological structures- Radiation effects on microscopic biological structures- Existing bio-chemical models- Existing Monte Carlo codes

WORK TEAM DEFINITIONWORK TEAM DEFINITION

Barbara MascialinoJuly 26th, 2004 INFN-Genova

Milestone 2: October 19th 2004

- Review of functionality

- Review and update of the User Requirement User Requirement

DocumentDocument

produced during the

First PhaseFirst Phase of the study

Barbara MascialinoJuly 26th, 2004 INFN-Genova

Milestone 3: March 19th 2006

First iteration: explorative prototypeFirst iteration: explorative prototype(verify capabilities to satisfy the User Requirements)

- Update of the User Requirements

- Study of the User Requirements

- Design

- Implementation

- Test

- Documentation

Barbara MascialinoJuly 26th, 2004 INFN-Genova

Milestone 4: March 19th 2007

Secon iteration:Secon iteration: Modelisation of radiation interactions with macroscopic biological Modelisation of radiation interactions with macroscopic biological

structuresstructures Update of the User Requirements

Study of the User Requirements Design

Implementation Test Documentation

Modelisation of radiation interactions with cellular structuresModelisation of radiation interactions with cellular structures Update of the User Requirements

Study of the User Requirements Design Implementation Test Documentation

Modelisation of radiation interactions with microscopic biologicalModelisation of radiation interactions with microscopic biological structuresstructures

Update of the User Requirements Study of the User Requirements Design Implementation Test Documentation

Barbara MascialinoJuly 26th, 2004 INFN-Genova

Milestone 5: March 19th 2008

Third iteration:Third iteration:

Modelisation of radiation interactions with macroscopic biological Modelisation of radiation interactions with macroscopic biological structures structures

Update of the User Requirements Study of the User Requirements

Design Implementation Test Documentation

Modelisation of radiation interactions with cellular structuresModelisation of radiation interactions with cellular structures Update of the User Requirements Study of the User Requirements Design Implementation Test Documentation

Modelisation of radiation interactions with microscopic biological Modelisation of radiation interactions with microscopic biological structuresstructures

Update of the User Requirements Study of the User Requirements Design Implementation Test Documentation

Barbara MascialinoJuly 26th, 2004 INFN-Genova

“Finally”

Cellular specialisation?

Cellular position?

Cellular status?

Oxigen component?