Page 1 of _4_NRC FORM 7 U.S. NUCLEAR REGULATORY COMMISSION APPROVED SY OMS: NO. 3150·0027 EXPIRES: 06/30/2009(8-2007) Estimated burden per response to comply with this mandatory collection request: 2.4 hours. This10 CFR 110 submittal is reviewed to ensure that the applicable statutory, regulatory, and policy considerations

are satisfied. Send comments regarding burden estimate fo the Records and FOIA/Privacy

APPLICATION FOR NRC EXPORT/IMPORT Services Branch (T-5 F52), U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001,or by internet e-mail to infocollects@nrc.gov, and to the Desk.Officer, Office of Infonmation and

LICENSE, AMENDMENT, OR RENEWAL Regulatory Affairs, NEOB-10202, (3150-0027), Office of Management and Budge~ Washington,DC 20503. If a means used to impose an infonmationcollection does not display a currently valid

(See Instructions on Page 5)OMB control number, the NRC may not conduct or sponscr, and a person is not required torespond to, the infonmationcollection.

1"_ ." ,{2~BLlC

PATE RECEiVED ;\ -~P~R'I1.k FOR'NRC USE' ONt y OR [] NON·PUBI:.IC

I \---Z.-1L ~

LICENSE NUMBER DOCKET NUMBER ADAMS ACCESSION NUMBER

YmUv\ LI'1.S. II O{)~O( 0/PART B. TO BE COMPLETED FOR ALL LICENSES, AMENDMENTS, RENEWALS OR NOTIFICATIONS

(If more space is needed to complete any of the items, use Pages 3·4 first, and then attach additional sheets, if necessary.)

1. NAME AND ADDRESS OF APPLICANT/LICENSEE 1a. NAME OF APPLICANT'S CONTACT 1b. APPLICANT'S REFERENCE NUMBER

Cambridge Isotope Laboratories, Gary Ionta

Inc. tc. PHONE NUMBER 1d. FAX NUMBER

(978) 749-8000 (978) 749-276850 Frontage Road

1e. E-MAIL ADDRESSAndover, MA. 01810 garyi@isotope.com

2. TYPE OF ACTION REQUESTED (Check One)

[l] EXPORT D NOTIFICATION OF D IMPORT D COMBINED EXPORTIIMPORT D AMENDMENT/RENEWAL(Parts B, C, E) EXPORT OF (Parts B, D, E) (Parts B, C, D, E) Existing License Number:

INCIDENTALRADIOACTIVEMATERIAL (PART C, E)

3. CONTRACT NUMBER(S) 4. FIRST SHIPMENT DATE 5. LAST SHIPMENT DATE 6. PROPOSED EXPIRATION DATE

12/0112013 12/0112018 12/0112018

PART C. TO BE COMPLETED FOR EXPORT ONLY OR COMBINED LICENSES, AMENDMENTS, OR RENEWALS(If more space is needed to complete any of the items, use Pages 3-4 first, and then attach additional sheets, if necessary.)

7. NAME(S) / ADDRESS(ES) OF SUPPLIERS 8. NAME(S) / ADDRESS(ES) OF INTERMEDIATE 9. NAME(S) / ADDRESS(ES) OF ULTIMATEAND/OR OTHER PARTIES TO THE EXPORT FOREIGN CONSIGNEE(S) FOREIGN CONSIGNEE(S)

Cambridge Isotope Goss Scientific Instruments AGT International Unit 18Laboratories, Inc. Unit 1, Technology Center Towers Close, Crewe, CW250 Frontage Road Dairy House Farm, Worleston 6QF, UKAndover,MA.01810 Nantwich, Cheshire CW5

6DN, UKAlso see page 3

Also see page 3

7a. FUNCTION(S) PERFORMED/SERVICE(S) PROVIDED 8a. INTERMEDIATE USE(S) 9a. ULTIMATE END USE(S)

Supplier/Distributor See Page 3 See Page 310. DESCRIPTION OF RADIOACTIVE MATERIALS, SEALED SOURCES, 10a. MAX TOTAL VOLUME / 10b. MAX ENRICHMENT 10e. MAX ISOTOPE

NUCLEAR FACILITIES, EQUIPMENT, OR COMPONENTS; FOR ELEMENT WGT (KG). OR ORWGT% WGT(KG)NUCLEAR EQUIPMENT INCLUDE TOTAL DOLLAR VALUE OF TOTAL ACTIVITY (TBq)EQUIPMENT FOR EXPORT

Non-radioactive 10,000 kg - 90% as 99.99% N/ADeuterium gas deuterium oxide, non-radioactiveDeuterium oxide remaining as gas material, notDeuterium compounds and compounds. radioactive

waste D11. FOREIGN OBLIGATIONS (BY COUNTRY AND BY PERCENTAGE OF MAXIMUM TOTAL VOLUME)

NRC FORM 7 (8-2007) PRINTED ON RECYCLED PAPER

Page 2 of 4

NRC FORM 7(8-2007)10 CFR 110

U.S. NUCLEAR REGULATORY COMMISSION

APPLICATION FOR NRC EXPORT/IMPORTLICENSE, AMENDMENT, OR RENEWAL (Continued)

PART D. TO BE COMPLETED FOR IMPORT ONLY, OR COMBINED LICENSES, AMENDMENTS, OR RENEWALS(If more space is needed to complete any of the items, use Pages 3-4 first, and then attach additional sheets, if necessary.)

12. NAME(S) I ADDRESS(ES) OF FOREIGNSUPPLIERS AND/OR OTHER PARTIESTO IMPORT

12a. NRC EXPORT LICENSE NUMBER(S)(if applicable)

17. ADDITIONAL INFORMATIONPROVIDED ON PAGES 3, 4,AND/OR ON SEPARATE SHEETS?

Gary IontaExport Compliance Officer

13. NAME(S) I ADDRESS(ES) OF INTERMEDIATE 14. NAME(S) I ADDRESS(ES) OF ULTIMATECONSIGNEE(S) CONSIGNEE(S)

13a. LICENSE NUMBER(S) I EXPIRATION DATE(S) 14a. LICENSE NUMBER(S) I EXPIRATION DATE(S)

13b. INTERMEDIATE USE(S) 14b. ULTIMATE END USE(S)

15. DESCRIPTION OF RADIOACTIVE MATERIALS, SEALED SOURCES,NUCLEAR FACILITIES

15a. MAX TOTAL VOLUME I 15b. MAX ENRICHMENT 15c. MAX ISOTOPEELEMENT WGT (KG), OR OR WGT % WGT (KG)TOTAL ACTIVITY (TBq)

16. FOREIGN OBLIGATIONS (BY COUNTRY AND BY PERCENTAGE OF MAXIMUM TOTAL VOLUME)

PART E. TO BE COMPLETED FOR ALL LICENSES, AMENDMENTS, OR RENEWALS

IlJ YES D NO17a. COPIES OF RECIPIENTS'

AUTHORIZATIONS PROVIDED? DYES [l] NO

18 CERTIFICATION' I, the applicant's authorized official, hereby certify that this application is prepared in conformity with Title10,. . Code of Federal Regulations, and that all information provided is correct to th e best of my knowledge.

18a. PRINT NAME AND TITLE OF AUTHORIZED OFFICIAL 18c. DATE

Page 3 of 4

NRC FORM 7(8-2007)10 CFR 110

U.S. NUCLEAR REGULATORY COMMISSION

APPLICATION FOR NRC EXPORT/IMPORTLICENSE, AMENDMENT, OR RENEWAL (Continued)

ADAMS ACtESSION NUMElER'· .

ADDITIONAL INFORMATION (Reference applicable block numbers from page 1 and/or page 2 for each entry)

Form NRC 7. Part C 8. - Name(s)/ Address(es) ofIntermediate foreign consignee(s)Goss Scientific Instruments, Unit 1, Trechnology Center, Dairy House Farm, Worleston,Nantwich,Cheshire CW5 6DN, UKCK Gas Products LTD., 3 Murrell Green Business Park, Hook Hampshire RG27 9GR, UKCK Gas Products LTD., Ashby Suite, Wellington House, Leicester Road, Ibstock, LeichestershireLE67 6HO, UKLGC Standards, Queens Road, Teddington TWll OLY,UK

NRC 7. Part C. 9a. - Ultimate foreign consignee(s)

Almac Sciences, Almac House, 20 Seagoe Industrial Estate, Craigavon, BT63 5QD, UKAscent Scientific, LTD., Unit 3 Avon Riverside Estate, Victoria Road Avonmouth, Bristol, UKAstrazeneca UK LTD., Silk Road Business Park, Alderley Park, RM 50F23, Macclesfield SKlO 2NA,UKBachem UK, Limited, Delphi Court, Sullivans Way, Sherdley Business Park, St. Helens, MerseysideWA95GL, UKBP Exploration OP CO LTD-EPT, (08l6)-EPT, Mitcheldean, Gloucestershire, GL17 OWH, UKEastgate Labs, 168 Eastegate, Louth, Lincolnshire, LNll 9AB, UKImperial College, Cell & Molecular Biology (CMB), 2nd FLR, Sir Alexander Fleming, ImperialCollege Road, London SW7 2AZ, UKInfineum UK LTD., Milton Hil, Abingdon, Oxfordshire, OX13 6BB, UKInstitute of Cancer Research, Central Services, 15 Cotswold Road, Belmont, Surrey, SM2 5NG, UKJohn Moores University, James Parsons Building, Byrom St., Liverpool, L3 3AF, UKMedical Research Council, Shared Services Center, North Star House, North Star Avenue, SwindonSN2lFF, UKMedical Research Council, Hills Road, Cambridge, Cambridgeshire, CB2 2QH, UKMI Swaco, Holburn House, 475-485 Union St., Aberdeen ABll 6DB, Scotland, UKNewcastle University, ICM, FLR 4, W. Leech Building, Framlington Place, Newcastle NE2 4HH,UKOxford University, Dept. of Physiology, Anatomy & Genetics, Sherrington Parks Road. Oxford, UKPepsico International LTD. R&D, Beaumont Leys, 4 Leycroft Road, Leicester L34 lET, UKPhoenix Petroleum & Energy LTD. Unit 24lA Magdalen RD. Wandsworth London SW18 3PA, UKProteome Sciences PLC, Coveham House, Downside Bridge Road, Cobham KT1l3EP, UKSelcia Limited, Fyfield Business & Research Park, Fyfield Road, Ongar, Essex CM5 OGS,UKShell Global Solutions, 72 Gordon St. Glasgow Gl 9BT, UKShell Research Limited, Shell Technology CTR. Thorton, Chester, UKSiemens PLC A&F Milburngate House, Durham DHI 5TZ, UKSt George's Hospital Medical School, Univ. of London, Cranmer Terrace, London SW17 ORE, UK G

Page 4 of 4

NRC FORM 7(8-2007)10 CFR 110

U_S_NUCLEAR REGULATORY COMMISSION

APPLICATION FOR NRC EXPORT/IMPORTLICENSE, AMENDMENT, OR RENEWAL (Continued)

ADDITIONAL INFORMATION (Reference applicable block numbers from page 1 and/or page 2 for each entry)

NRC 7. Part C. 9a. - Ultimate foreign consignee(s) (Cont.)The University of Manchester, John Owens Bldg., Oxford Road, Manchester M13 9PL, UKUniversity Newcastle Upon Tyne, Wellcome RES Labs/ HNDC, Royal Vic inf/Queen Vic, NewcastleTyne NE14LP, UKUniversity of Glasgow, University Dept. Child Health, Yorkhill Hospitals, Glasgow G3 8SJ, UKUniversity College London, Dept. of Biology, Darwin BLDG. Gower St., London WC1E 6BT, UKUniversity of Aberdeen, Institute of Medical Sciences, Fosterhill, Aberdeen AB25 2ZD, UKUniversity of Birmingham, Edgbaston, Birmingham B15 2TT, UKUniversity of Bristol, School of Chemistry, Cantock's Close, Bristol BS8 1TS, UKUniversity of Cambridge, Dept. of Biochemistry, Tennis CT. Road, Cambridge CB2 1QW,UKUniversity of Cambridge, Chemistry Dept., Lensfield Road, Cambridge CB2 1EW, UKUniversity of East Anglia, Faculty of Science, Finance Office, Norwich, UKUniversity of Edinburg, Royal Infirmary, Lauriston PL., Edinburg EA3 9YW, UKUniversity of Leeds, EC Stoner Building. Leeds LS2 9JT, UKUniversity of Liverpool, Veterinary Preclinical Science, VET Bldg. RlVI116 - PO Box 147, LiverpoolL693BX, UKUniversity of Oxford, Center for Molecular Science, South Parks Road, Oxford OX13QT, UKUniversity of Oxford, Dept. of Pediatrics, John Radcliffe Hospital, Headington Oxford OX3 9DU, UKUniversity of Oxford, Dyson Perrins Laboratory, South Parks Road, Oxford OX1 3QY, UKUniversity of Oxford, Chemical Reasearch Laboratory, Manfield Road, Oxford, Oxfordshire OX13TA, UKUniversity of Reading, Dept. of Chern. Harborne Bldg. (Biocentre) Whiteknights CMPS, ReadingRG66AS ,UKUniversity of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, UKUniversity of Southampton, Finance Dept. Bldg. 37, Southampton S017 1BJ, UKUniversity of St. Andrews, Biomedical Sciences Bldg. School of Biology North Haugh, St. AndrewsFIFE KY16 9ST, UKUniversity of Warwick, Dept. of Chemistry, Gibbet Hill Road, Coventry CV4 7AL, UKVertex Pharmaceuticals (Europe). LTD., 88 Milton Park, Abingdon, Oxfordshire OX14 4RY, UKNRC 7. Part C. 9a. - Ultimate end use(s)Cambridge Isotope Laboratories, Inc. plan to sell the various deuterium compounds to intermediateand ultimate consignees (listed in Part C. 9., C.9a) for further distribution into the United Kingdommedical, pharmaceutical, chemical and industrial markets. Their customers in United Kingdomtypically use these materials in relatively small quantities, (less that 1 Kg) for scientific research. Thistype of research may include identification of chemicals in reaction pathways, metabolic studies, orenvironmental analysis. No material will be used in any activity related to isotope separation, heavywater production, or in the fabrication of nuclear fuel. D

..~ ..r ~;-\.:ell

Cambridge Isotope Laboratories, Inc ..........................................................................................................

50 Frontage Road, Andover, MA 01810-5413 USA

PH: 800.322.II74 (N. AMERICA) PH: 978.749.8000

FAX: 978.749.2768 WEB: www.isotope.com

October, 312012

Deputy DirectorOffice of International ProgramsU.S. Nuclear Regulatory CommissionWashington, DC. 20555-0001

Dear Deputy Director:

Enclosed please find three (2) completed NRC Export License applications (form 7) for the export ofdeuterium gas, deuterium oxide and deuterium compounds. Each of these licenses applications are countryspecific for the United Kingdom and United Arab Emirates. A fee of$12,300.00 per application has beenassigned by Ms. Jennifer Tobin- Wollenweber which has been submitted electronically per the License fee andAccounts Receivable Branch instructions.

If you have any questions please contact me at your convenience.

Gary J. IontaEH&S OfficerlExport Compliance OfficerCambridge Isotope Laboratories Inc.50 Frontage RoadAndover, MA. 01810(978) 296-1924garyi@isotope.com