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Tel: 1-631-871-5806 Fax: 1-631-207-8356

45-1 Ramsey Road, Shirley, NY 11967, USA

Email: [email protected]

http://www.creativebiolabs.net/

mailto:[email protected]

About Us

Over the last 10 years, Creative Biolabs has

become a leader of recombinant antibody (rAb)

discovery and manufacturing, providing high quality

service to customers in academia and industry

fields all over the world.

Our cutting-edge hybridoma development and phage display platforms allow the

production of the most comprehensive list of recombinant antibody products and

extensive service portfolio at the most competitive price. Our products range from

antibody / peptide libraries, Biosimilar cell lines, Chimeric antigen receptor (CAR)

products, antibody-drug conjugates (ADCs) to engineered antibodies such as

therapeutic antibodies, single-domain antibodies, bispecific antibodies and intrabodies.

We also provide professional custom antibody discovery and engineering services,

featuring phage display library construction, antibody humanization, chimerization,

engineered antibody production (Fab, scFc, tribody, bispecific antibody, SdAb,

minibody, etc.), antibody labeling, hybridoma/stable cell line development, membrane

protein production and cGMP-manufacturing which enable larger scale antibody

production for development of animal-based assays and clinical trials.

www.creativebiolabs.net 2 / 30



THERAPEUTIC

ANTIBODY

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Products List

Creative Biolabs is a pioneer and undisputed global leader in the rapidly emerging

market for therapeutic antibodies. We offer a full range of therapeutic antibodies

currently available for research of a wide variety of diseases. We guarantee

generated endotoxin free antibodies are fully functional and ready to use in animal-

based assays and clinical trials.

I Autoimmune and Inflammatory Diseases

Cat. No Product Name Antibody

Name/Clone Related Disease

TAB-H02 Anti-Human ITGA4+ITGB7

Therapeutic Antibody

Abrilumab

Ulcerative colitis

TAB-010 Anti-Human TNF Therapeutic Antibody

Adalimumab Juvenile Idiopathic Arthritis

TAB-115 Anti-Human SOST Therapeutic Antibody

TAB-103 Anti-Human IL12+IL23 Therapeutic Antibody

TAB-134 Anti-Human IL17RA Therapeutic Antibody

TAB-117 Anti-Human MCP-1 Therapeutic Antibody

TAB-107 Anti-Human CD4 Therapeutic Antibody

Blosozumab Postmenopausal women osteoporosis

Briakinumab Crohn's disease

Brodalumab Psoriatic arthritis

Carlumab Immune disease

Cedelizumab Allograft rejection

TAB-717 Anti-APP Therapeutic Antibody Aducanumab Alzheimer's disease

TAB-094

TAB-260

Anti-Human IL6 Therapeutic

Antibody

Anti-Human CD4 Therapeutic

Antibody

Anti-Human ITGA4 Therapeutic

Antibody

Anti-Human CD11a Therapeutic

Antibody

Clazakizumab Crohn's disease

Tregalizumab Psoriasis

TAB-022 Natalizumab Multiple sclerosis

TAB-108 Odulimomab Allograft rejection

TAB-007 Anti-Human IGHE Therapeutic

Antibody

Anti-Human IL4 Therapeutic

Antibody

Omalizumab Allergic asthma

TAB-221 Pascolizumab Allergy


TAB-772 Anti-CD20 Therapeutic Antibody Ocrelizumab Multiple sclerosis


Products List

II Cancers


Name/Clone Indications

TAB-731 Anti-GD2 Therapeutic Antibody Dinutuximab Neuroblastoma

TAB-114 Anti-Human CA-125 Therapeutic Antibody Abagovomab Ovarian cancer

TAB-106 Anti-Human EPCAM Therapeutic Antibody Adecatumumab Prostate and breast cancer

TAB-201 Anti-Human Mesothelin Therapeutic Antibody Amatuximab Pancreatic cancers

TAB-011 Anti-Human VEGF Therapeutic Antibody Bevacizumab Colorectal cancers,

metastatic

TAB-728 Anti-CD19 Therapeutic Antibody Blinatumomab Acute lymphocytic leukemia

TAB-078 Anti-Human IGF1 Receptor Therapeutic Antibody Cixutumumab Non-small cell lung cancers

TAB-203 Anti-Human DR5 Therapeutic Antibody Conatumumab Non-small cell lung cancers

TAB-764 Anti-ganglioside GD3 Therapeutic Antibody Mitumomab Small cell lung carcinoma

TAB-209 Anti-Human IGF1 Receptor Therapeutic Antibody Robatumumab Blood cancers

TAB-206 Anti-Human CTLA4 Therapeutic Antibody Ticilimumab Cancers

TAB-207 Anti-Human CD20 Therapeutic Antibody Ublituximab Chronic lymphocytic

leukemia

TAB-264 Anti-Human NRP1 Therapeutic Antibody Vesencumab Solid tumors

TAB-H35 Anti-Human EGFR Therapeutic Antibody Futuximab Colorectal cancers


TAB-715 Anti-CTAA16.88 Therapeutic Antibody Votumumab Colorectal tumors

TAB-005 Anti-Human ErbB2 Therapeutic Antibody Trastuzumab Breast cancers

TAB-144 Anti-Human CD30 Therapeutic Antibody Iratumumab Hodgkin's lymphoma

TAB-H11 Anti-Human NOTCH1 Therapeutic Antibody Brontictuzumab Lymphoma

TAB-133 Anti-Human CD20 Therapeutic Antibody Afutuzumab Lymphoma

TAB-H01 Anti-Human ITGAV Therapeutic Antibody Abituzumab Colorectal cancers,

metastatic

TAB-150 Anti-Human HLA DR beta Therapeutic Antibody Apolizumab Chronic lymphocytic

leukemia

TAB-H09 Anti-Human CD44 Therapeutic Antibody Bivatuzumab

mertansine Squamous cell carcinoma

TAB-H14 Anti-Human GPC3 Therapeutic Antibody Codrituzumab Hepatocellular carcinoma

TAB-H56 Anti-Human MUC1 Therapeutic Antibody Pemtumomab Cancers

TAB-877 Anti-Human Tenascin C/TNC Therapeutic Antibody Tenatumomab Cancers

TAB-880 Anti-Human Frizzled receptor Therapeutic Antibody Vantictumab Solid tumors

TAB-033 Anti-Human CEACAM5 Therapeutic Antibody Labetuzumab Colorectal cancers


Products List

III Other Diseases


Name/Clone Indications

TAB-716 Anti-C. difficile Toxin A Therapeutic

Antibody

Actoxumab Clostridium difficile infectious

diarrhea

TAB-718 Anti-TNFα-Therapeutic-Antibody Afelimomab Sepsis

TAB-149 Anti-Human RHD Therapeutic Antibody Atorolimumab Hemolytic disease of the

newborn

TAB-175 Anti-Human Phosphatidylserine Therapeutic Antibody

Bavituximab Viral infections

TAB-725 Anti-C. diff toxin B Therapeutic Antibody Bezlotoxumab Clostridium difficile infectious

diarrhea

TAB-161 Anti-Human IL1 beta Therapeutic Antibody

Gevokizumab Cardiovascular disease

TAB-100 Anti-Human TGF beta 2 Therapeutic Antibody

Lerdelimumab Glaucoma surgery

TAB-009 Anti-RSV Therapeutic Antibody Palivizumab Respiratory Syncytial Virus

TAB-888 Anti-Human Myostatin/GDF8 Therapeutic Antibody

Stamulumab Muscular dystrophy

TAB-159 Anti-Human CD3 Therapeutic Antibody Teplizumab Type 1 diabetes

TAB-157 Anti-E. coli Shiga-like toxin II B Therapeutic Antibody

Urtoxazumab Diarrhoea caused by E. coli

More products, please visit our website: http://www.creativebiolabs.net

TAB-111 Anti-Human NGF Therapeutic Antibody Tanezumab Pain

TAB-16 Anti-CMV Therapeutic Antibody Sevirumab Cytomegalovirus (CMV)

infections

TAB-775 Anti-oxLDL Therapeutic Antibody Orticumab Atherosclerosis

TAB-734 Anti-TFPI Therapeutic Antibody Concizumab Hemophilia

TAB-H10 Anti-Human PCSK9 Therapeutic Antibody Bococizumab Hypercholesterolemia

TAB-242 Anti-Human RTN-4 Therapeutic Antibody Atinumab Spinal cord injury





RECOMBINANT

ANTIBODY

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Products List

Creative Biolabs is a pioneer of recombinant

antibody (rAb) discovery and manufacture,

providing the most comprehensive list of rAb

products in the world.

We have developed proprietary procedures for

Hi-Affi™ recombinant antibody production,

with optimized library construction and

screening processes using hybridoma or phage

display technology.

PABL-424 Recombinant Mouse Anti-

CD28 Antibody 1C6

Western Blot; Enzyme-linked

Immunosorbent Assay;

Functional Study

PABC-211 Recombinant Anti-CD38 Antibody

Recombinant Anti-EGF

HB7 Enzyme-linked Immunosorbent Assay

Enzyme-linked Immunosorbent

MOB-305 Antibody

Assay; Western blot; Flow

Cytometry; Functional Study

PABL-462 RecombinantHuman Anti- EGFR Antibody

C225 Flow Cytometry

PABW-171 Recombinant Anti-EGFR Antibody

mAb175 Western Blot

PABC-158 Recombinant Anti-ERBB2ECD Antibody (Pertuzumab) 2C4

ImmunoprecImmunoprecipitati onitation, Neutralization

PABL-128 Recombinant Mouse Anti- HER3 Antibody RG7116

Western blot; Blocking; Functional Study

MHH-358 Recombinant HumanAnti- FGFR Antibody

Flow Cytometry; Neutralization;

Biosensors; Functional Study


PABL-507 Recombinant Mouse Anti-HIV

Antibody RoAb13

Western blot; Enzyme-linked

Immunosorbent Assay;

Functional Study

Cat No. Product Name Clone Applications


Products List

Cat No. Product Name Clone Applications

PABL-271

Recombinant Human Anti-MET

Antibody

5D5

Western blot; Blocking; Functional

Study

PABZ-155 Recombinant Anti-MET Antibody (Onartuzumab) OA5D5.v2

Enzyme-linked Immunosorbent Assay, Neutralization

PABL-422

Recombinant Human Anti-CD20

Antibody 2F2

Western Blot; Enzyme-linked

Immunosorbent Assay; Functional

Study

MHH-359 Recombinant Human Anti-

FGFRL1 Antibody

Enzyme-linked Immunosorbent Assay;

Immunofluorescence; Functional Study

MOM-H64 Recombinant Anti-S1P MAb Enzyme-linked Immunosorbent Assay;

Western Blot



HOM-19501 Recombinant Anti-XCR1 Mab Enzyme-linked Immunosorbent Assay;

Western Blot; Immunofluorescence

MHH-19 Recombinant Mouse Anti-AAV 2

Antibody

Immunofluorescence; Neutralization;

Functional Study

MHH-122 Recombinant Human Anti-BRAF

Antibody

Immunoprecipitation; Functional Study

PABC-021 Recombinant Anti-CD52

Antibody

CAMPATH-

1G

Western Blot, Immunohistochemistry,

Immunofluorescence, Functional Study

MHH-844 Recombinant Human Anti-RET

Antibody

Western blot; Neutralization; Functional

Study




GLYCO-ENGINEERING

ANTIBODY

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Equip your antibody for

Enhanced Potency

In support of our mission to enable cutting edge advances in the life sciences, we

Creative Biolabs recently launched the following glyco-engineering therapeutic

MAbs that describe the biological effects exerted by different glycan forms attached to

N297 of an IgG Fc or Fab, and how engineering of those glycans can be used to

obtain therapeutic MAb candidates with widely different biological properties.


✓ Non-glycosylated IgGs for lowered effector function;

✓ Low- or non-fucosylated oligosaccharides result in higher ADCC;

✓ FAb glycosylation typically enhance the solubility of the antibody


Glycoengineered Antibody

Fc glycosylation

N-glycosides from N297 in the CH2 domain of a

human IgG is typically bi-antennary, fucosylated G0,

G1, and G2 , with minor non-fucosylated and

sialylated.

Fab glycosylation

A significant role in antigen binding and thus

host defense; A positive, neutral, or negative

impact on the binding of certain antigens, and

typically enhance the solubility of the antibody.

Deglycosylated

Retain the FcRn interactions and long serum half-life;

lowered effector function; more susceptible to

proteolysis than glycosylated IgGs.



Glycoengineered Antibody

Low- or Non fucosylated

• Higher affinity for FcγRIIIa

• Enhanced ADCC

Sialylated

• Anti-inflammatory

• Decreased ADCC

Non-sialylated

• Enhanced ADCC

High-mannose

• Low C1q binding

• Enhanced ADCC



Cat. No Product Name Molecular

target Major indication Protein format

Gly-001CL

Romiplostim

TPO-R

Thrombocytopenia

Fc-peptide fusion (“peptibody”)

produced in E. coli; non-glycosylated

Gly-002CL TRX4 CD3 Type 1 diabetes Non-glycosylated, humanized IgG1

Gly-004CL Clazakizumab IL-6

Non-small cell lung

cancer-related fatigue

and cachexia

Non-glycosylated, humanized IgG

produced in yeast

Gly-006CL Benralizumab IL-5R SLE Non-fucosylated IgG1κ

Gly-008CL

Anti-CD70

monoclonal antibody

(MDX-1411)

CD70

Inflammation and

oncology Human IgG; non-fucosylated

Gly-010CL Ublituximab CD20 Lymphoid leukemia

Low fucose-chimeric IgG1; rat

myeloma YB 2/0 produces low fucose

glycans

Gly-012CL

Anti-IGF-1R human

monoclonal antibody

(BIIB022)

IGF-1R Solid tumors Human IgG4; non-glycosylated

Gly-014CL Roledumab RhD factor

Rhesus incompatibility

between mother and

fetus

Low fucose-chimeric IgG1; rat

myeloma YB 2/0 produces low fucose

glycans



Gly-015CL Cetuximab EGFR

Metastatic colorectal

cancer, metastatic non- The only commercial antibody to

small cell lung cancer possess V-region glycosylation, which

and head and neck contains an N-linked oligosaccharide

cancer occupying N88 of the VH chain

Gly-013CL Anti-ganglioside GM2

monoclonal antibody GM2

BIW-8962

Blood tumors IgG1; non-fucosylated

Gly-011CL Anti-CD19 fully

human monoclonal

antibody MDX-1342

CD19 CLL, RA Human IgG1; non-fucosylated

Gly-009CL

Anti-CD30

monoclonal antibody CD30

(MDX-1401)

Inflammation and

oncology Human IgG1; non-fucosylated

Gly-005CL Blisibimod Blys RA Anti-BLys peptibody - produced in E.

coli; non-glycosylated

Gly-003CL Obinutuzumab CD20 Front-line CLL and

other cancers

IgG1κ humanized; non-fucosylated

form generated using Glycart

technology

Gly-007CL Mogamulizumab CCR4 Inflammation and

oncology Humanized IgG1; non-fucosylated

Products List




SINGLE-DOMAIN

ANTIBODY

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Creative Biolabs provides the most complete

collection of SdAb products the world has ever

had. From premade to immunized phage

display library, our proprietary SdAb platform

allows rapid generation and large-scale

production of high affinity novel biological

therapeutics that have potential in a wide range

of human diseases.



Product Name Host Reactivity Cat. No

Anti-Adenovirus VHH Single Domain Antibody

NABG-009

Anti-B-cell lymphomas VHH Single Domain Antibody NAB-242-sdAb

Recombinant Anti-Norovirus VHH Single Domain

Antibody

PNBL-071

Anti-rabies virus glycoprotein VHH Single Domain

Antibody

NAB-2114-VHH



Anti-IL22 VHH Single Domain Antibody NAB-1442-sdAb

Anti-TNFRSF10B VHH Single Domain Antibody NABL-052

Anti-MET Therapeutic Antibody TAB-001MZ-VHH

Anti-RSV VHH Single Domain Antibody NAB-2162-sdAb

Anti-TNF VHH Single Domain Antibody NABL-051

Anti-PCSK9 VHH Single Domain Antibody NABG-050

Anti-Poliovirus P1 VHH Single Domain Antibody NAB-2097-VHH

Anti-SUMO tag VHH Single Domain Antibody NAB-1249-sdAb

Anti-rotavirus VHH Single Domain Antibody NABG-002

Anti-GFP VHH Single Domain Antibody NABC-002

Anti-HIV-1 gp120 VHH Single Domain Antibody NABG-082

Anti-HER2/neu Therapeutic Single Domain Antibody TAB-032CT

Anti-HIV-1 env VHH Single Domain Antibody NABG-057

Anti-HBV VHH Single Domain Antibody NAB-1234-sdAb

Anti-H3N2 VHH Single Domain Antibody NABG-075

Anti-H1N1 VHH Single Domain Antibody NABG-074

Anti-Egfr VHH Single Domain Antibody NABG-056

Anti-CEACAM5 VHH Single Domain Antibody NABL-080

Anti-TNFSF13B VHH Single Domain Antibody NABG-024

Anti-IL23A VHH Single Domain Antibody NAB-1953-VHH

Products List




ANTIBODY-CYTOKINE

FUSION PROTEINS

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Creative Biolabs is a professional manufacturer of

Antibody-cytokine Fusion Proteins (ACFPs). We

has developed a series of functional cytokine fusion

antibodies simultaneously. These immunocytokine

molecules were shown to have striking anti-tumor

activity and may provide a useful approach to the

treatment of cancer.

Antibody-cytokine fusion proteins, which consist of

cytokines fused to an antibody, have the properties of

all components and acquire advantages compared to

proteins alone. Structurally, there are two main types

of ACFPs which cytokines can be alternatively fused to

either whole immunoglobulin (Ig fusion) or antigen-

binding fragments such as Fabs, single-chain variable

fragments (scFvs) or divalent derivatives thereof.

Advantages of Antibody-cytokine Fusion Proteins:

• Good biological activity of both components

• Low or non immunogenic

• Endotoxin free

• Subnanomolar high affinity

• High production yield

• Great stability

• Outstanding solubility in aqueous solutions



Cat. No Product Name Antibody Clone

ACFP-SH146 Anti-PD-L1 Immunocytokine, IgG (atezolizumab)-IL-15Rα sushi

domain/IL-15

Atezolizumab

ACFP-SH161 Anti-CD38 Immunocytokine, IgG (daratumumab)-IFNα Daratumumab

ACFP-SH129 Anti-CD3 Immunocytokine, TNF-IgG (OKT3) OKT3



ACFP-SH132 Anti-CD20 Immunocytokine, IgG (Rituximab)-IL2α Rituximab

ACFP-SH017 Anti-MUC-1 Immunocytokine, scFv-Fc (C595)-IL2 C595

ACFP-SH059 Anti-IL2 Immunocytokine, IL2-IgG (S4B6) S4B6

ACFP-SH002 Anti-GD2 Immunocytokine, IgG (14.18)-IL2 14.18


ACFP-SH031 Anti-EpCAM Immunocytokine, IgG (huKS)-IL12 HuKS

ACFP-SH169 Anti-CEA Immunocytokine, p40-ScFv (T84.66)-p35 T84.66

ACFP-SH079 Anti-EGFR Immunocytokine, IgG (Ch225)-IL2 Ch225

ACFP-SH130 Anti-CD28 Immunocytokine, IL2-IgG (15E8) 15E8


ACFP-SH024 Anti-MHC class II Immunocytokine, IgG (chCLL-1)-GM-CSF ChCLL-1

ACFP-SH064 Anti-HER2/neu Immunocytokine, IgG (trastuzumab)-IL2 Trastuzumab

ACFP-SH122 Anti-CD4 Immunocytokine, IL2-IgG OKT4

ACFP-SH128 Anti-CD3 Immunocytokine, IgG (OKT3)-IL2 OKT3

ACFP-SH119 Anti-CD8 Immunocytokine, IL2-IgG (OKT8) OKT8

ACFP-SH124 Anti-CD30 Immunocytokine, scFv-Fc (HRS3)-IL12 HRS3

ACFP-SH066 Anti-gp240 antigen Immunocytokine, scFv (ZME-018)-TNFα ZME-018 (scFvMEL)

Products List




INTRABODY

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Products List

9

Creative Biolabs is a professional manufacturer of

intrabodies and is specialized in providing all kinds of

intrabodies available for a variety of in vitro and in vivo studies.

Hot Intrabodies listed as follows:

Cat No. Product Name Type Applications

IAB-B008(G)

Anti-ERBB2

[+36GFP]

Intrabody

scFv-(+36GFP) Western blot; Immunocytochemistry;

Functional studies

IAB-B026(T) Anti-FGFR2

Intrabody [Tat] scFv-Tat

Immunocytochemistry;Neutralization; Functional studies

IAB-B037(G) Anti-HBeAg Intrabody [+36GFP] vhh-(+36GFP)

Immunocytochemistry; Neutralization; Functional studies

IAB-B035(G) Anti-Human MHC1 Intrabody [+36GFP] scFv-(+36GFP)

Enzyme-linked Immunosorbent Assay; Neutralization; Functionalstudies

IAB-B068(A) Anti-IAV PB2 Intrabody [(D-Arg)9]

scFv-(D-Arg) Western blot; Immunocytochemistry; Neutralization; Functionalstudies

IAB-B009(T) Anti-RAS Intrabody [Tat] scFv-Tat

Flow Cytometry; Immunofluorescence; Functional studies

IAB-B045(G) Anti-NCT Intrabody [+36GFP] scFv-(+36GFP)

Immunofluorescence; Enzyme-linked Immunosorbent Assay; Functionalstudies


IAB-B030(A) Anti-TLR2 Intrabody

[(D-Arg)9] scFv-(D-Arg)9

Immunocytochemistry; Neutralization;

Functional studies

IAB-B021(G) Anti-PTEN Intrabody

[+36GFP]

scFv-(+36GFP) Fluorescence-activated cell sorting; Enzyme-

linked Immunosorbent Assay;

Immunofluorescence; Functional studies

IAB-B040(A)

Anti-IAV NP Intrabody


Western blot; Neutralization;Functional

studies

IAB-B053(A) Anti-HIV gp120

Intrabody [(D-Arg)9] scFv-(D-Arg)9


Immunocytochemistry; Functionalstudies

IAB-B075(A) Anti-HCV C Intrabody



studies


Products List

9

Cat No. Product Name Type Applications

IAB-B007(A)

Anti-PREV Intrabody

[(D-Arg)9]

vhh-(D-Arg)9

Fluorescence-activated cell sorting;

Immunocytochemistry; Functionalstudies

IAB-B043(G) Anti-TLR9 Intrabody [+36GFP] scFv-(+36GFP)

Enzyme-linked Immunosorbent Assay; Immunocytochemistry; Functionalstudies

IAB-B057(G) Anti-SGK1 Intrabody [+36GFP] scFv-(+36GFP)

Western blot; Immunocytochemistry; Neutralization; Functionalstudies

IAB-B001(A) Anti-BaX Intrabody [(D-Arg)9]

vhh-(D-Arg) Enzyme-linked Immunosorbent Assay; Immunocytochemistry; Functionalstudies

IAB-B074(G) Anti-CD2 Intrabody

[+36GFP]

scFv-(+36GFP)



Functional studies

IAB-B070(A)

Anti-ADH I Intrabody




Functional studies



Fluorescence-activated cell sorting;

Immunocytochemistry; Functionalstudies scFv-Tat

Anti-CCR5 Intrabody

[Tat] IAB-B039(T)

IAB-B056(A) Anti-Vdr Intrabody


Protein fragment complementation;

Western blot; Functionalstudies

IAB-B067(A) Anti-VCAM-1

Intrabody [(D-Arg)9] scFv-(D-Arg)9

Fluorescence-activated cell sorting; Enzyme-

linked Immunosorbent Assay;

Immunofluorescence; Functional studies

IAB-B064(G) Anti-TEK Intrabody

[+36GFP] scFv-(+36GFP)


studies

IAB-B027(A) Anti-RELA Intrabody


Western blot; Coimmunopricipation;

Functional studies




THERAPEUTIC

PROTEIN

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Recently, Creative Biolabs’ innovative products and

services are used to augment the early discovery process in

life science research and ground breaking development of

protein therapeutics.

Hot Therapeutic Proteins listed as follows:

Cat No. Product Name Trade Name Clinical Use

TP-084CL

Abatacept

Orencia

Rheumatoid arthritis (especiallywhen

refractory to TNFa inhibition)

TP-089CL Alefacept Amevive Moderate to severe chronic plaquepsoriasis

TP-081CL Alemtuzumab Campath B-cell chronic lymphocyticleukaemia

TP-121CL Arcitumomab CEA-scan Colon and breast cancerdetection

TP-039CL Peginterferonalfa-2a Pegasys Adults with chronic hepatitisc

TP-003CL InsulinAspart

Novolog (Aspart),

Apidra (Glulisine),

Humalog (Lispro)

Diabetes mellitus


TP-042CL Interferon alfa-n3 Alferon N Condylomata acuminata (genital warts

caused by humanpapillomavirus)

TP-123CL Apcitide Acutect Imaging of acute venous thrombosis

TP-055CL Exenatide Byetta Type 2 diabetes resistant to treatmentwith

metformin and a sulphonylurea

TP-037CL Interferon alfacon-1 Infergen Chronic hepatitis c infection

TP-006CL Insulin zinc extended Lente,

Ultralente Diabetes mellitus


Cat No.

Product Name

Trade Name

Clinical Use

TP-023CL

Lactase

Lactaid

Gas, bloating, cramps and diarrhoea due

to inability to digestlactose

TP-074CL Lepirudin Refludan Heparin-induced thrombocytopaenia

TP-009CL

Mecasermin

Growth failure in children with GH gene Increlex

deletion or severe primary iGF1 deficiency

TP-063CL

Nesiritide

Acute decompensated congestiveheart Natrecor

failure

TP-056CL

Octreotide

Acromegaly, symptomatic reliefof viP-

Sandostatin secreting adenoma and metastatic

carcinoid tumours

TP-007CL

Pramlintide

Diabetes mellitus, in combination with Symlin

insulin

TP-104CL

Ranibizumab

Neovascular age-relatedmacular Lucentis

degeneration

TP-120CL

Satumomab

Pendetide

OncoScint Colon and ovarian cancer detection

TP-053CL Salmon Calcitonin Fortical,

Miacalcin

Postmenopausalosteoporosis

TP-115CL Sermorelin Geref

Diagnosis of defective growth-hormone

secretion



TP-116CL Secretin ChiRhoStim Diagnosis of pancreatic exocrine

dysfunction orgastrinoma

Products List




IMMUNOTOXIN

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Products List

Creative Biolabs is one of the first-in class global

manufacturers of immunotoxins and is professional in

pruducing all kinds of immunotoxins.

Hot Immunotoxins listed as follows:

Cat No. Product Name Molecule Class Related Disease

AGTO-G018D

Anti-EGFR immunotoxin

D2C7 (scFv)-DT

ScFv-DT

Tumor

AGTO-G072G Anti-AFP immunotoxin 80G (IgG)-Gel

AGTO-G049E Anti-MET immunotoxin (Fab)-PE

AGTO-L059G Anti-HIV immunotoxin G49 (IgG)-Gel

AGTO-G037D Anti-HIV-1 immunotoxin 3B3 (scFv)-DT

AGTO-L043L Anti-VEGFA immunotoxin Ng76 (scFv)-Luffin-β

AGTO-G015E Anti-CTLA4 immunotoxin (scFv)-PE

AGTO-G022D Anti-ERBB2 immunotoxin 4D5 (scFv)-DT

AGTO-L036E Anti-MUC1 immunotoxin C242 (Fab)-PE

AGTO-G062E Anti-TNFRSF8 immunotoxin Ki-3 (scFv)-PE

AGTO-G063S Anti-TNFRSF9 immunotoxin (scFv)-Sap

Anti-TNFRSF12A

IgG-Gel Hepatic carcinoma

Fab-PE Gastric cancer

IgG1-Gel AIDS

ScFv-DT Immunodeficiency virus type 1 (HIV-1) infection

ScFv-Luffin-β Melanoma

ScFv-PE Immunosuppressive Agent for Organ Transplant

ScFv-DT SK-OV-3 tumor

IgG2a-PE Colorectal tumor

ScFv-PE Lymphoma

ScFv-Sap Graft-versus-host diseas (GVHD) and the relapse of leukemia

AGTO-G061G immunotoxin ITEM-4 (scFv)-

Gel

ScFv-Gel Malignant Melanoma



Products List

Cat No. Product Name Molecule Class Related Disease

AGTO-L064E

Anti-MUC1 immunotoxin

H23 (scFv)-PE

ScFv-PE

Lung cancer, breast cancer

AGTO-G011E Anti-CD7 immunotoxin TH- 69 (scFv)-PE

AGTO-G021D Anti-EPCAM immunotoxin VB4-845 (scFv)-DT

AGTO-L013R Anti-EPCAM immunotoxin MOC31 (IgG)-RTA

AGTO-L037P Anti-NCAM1 immunotoxin N901 (IgG)-PAP

AGTO-L032R Anti-MCMV immunotoxin (IgG)-RTA

AGTO-G079E Anti-CD40 immunotoxin G28-5 (scFv)-PE

AGTO-G006E Anti-CD24 immunotoxin SWA11 (IgG)-PE

AGTO-G077D Anti-CD22 immunotoxin RFB4 (IgG)-DT

AGTO-L047R Anti-CD19 immunotoxin HD37 (scFv)-RTA

AGTO-G009G Anti-CD38 immunotoxin IB4 (IgG)-Gel

ScFv-PE Acute Leukemic T Cells

ScFv-DT Head and neck cancer

IgG1-RTA Hepatocellular carcinomas (HCC)

IgG1-PAP Small-cell lung cancer(SCLC)

IgG-RTA Cytomegalovirus-infected

ScFv-PE Non-Hodgkin's lymphoma and multiple myeloma

IgG-PE Colorectal tumors

IgG-DT B Cell Lymphoma

ScFv-RTA Head and neck squamous cell cancer or bladder cancer

IgG-Gel Non Hodgkin Lymphoma (NHL)





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Fax: 1-631-207-8356





Date post:	08-Oct-2020
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