Progress Against Kidney

Cancer

Progress Against Kidney Cancer

1970–1979

Progress Against Kidney Cancer

1970–19791977: Removing just part of the cancerous kidney is proven safe and effective

Progress Against Kidney Cancer

1980–1989

Progress Against Kidney Cancer

1980–19891985: Immunotherapy benefits patients with advanced renal cell carcinoma

Progress Against Kidney Cancer

1990–1999

Progress Against Kidney Cancer

1990–19991991: Introduction of laparoscopic surgery minimizes pain, recovery time

Progress Against Kidney Cancer

1990–19991992: First immunotherapy approved for kidney cancer

Progress Against Kidney Cancer

1990–19991995–1997: New treatment techniques introduced for small renal tumors

Progress Against Kidney Cancer

2000–Present

Progress Against Kidney Cancer

2000–Present2000: Combination of kidney removal and immunotherapy extends life

Progress Against Kidney Cancer

2000–Present2005: First FDA approval of a targeted drug for kidney cancer

Progress Against Kidney Cancer

2000–Present2006–2007: Two new targeted drugs are proven effective in major trials; FDA approvals follow

Progress Against Kidney Cancer

2000–Present2009: Everolimus approved for renal cell carcinoma if other drugs fail

2009: Bevacizumab approved for renal cancer after multiple studies confirm benefit

2009: Pazopanib approved for advanced kidney cancer

Progress Against Kidney Cancer

2000–Present2011: FDA approves axitinib for persistent kidney cancer

Progress Against Kidney Cancer

Five-Year Survival

47

52

57

62

67

72

1975

1977

1979

1981

1983

1985

1987

1989

1991

1993

1995

1997

1999

2001

2003

2005

2007

2009

Year of Diagnosis

% o

f Pa

tien

ts S

urv

ivin

g F

ive

Ye

ars

Source: National Cancer Institute

Progress Against Kidney Cancer

Mortality

0

1

2

3

4

5

6

7

8

1970

1972

1974

1976

1978

1980

1982

1984

1986

1988

1990

1992

1994

1996

1998

2000

2002

2004

2006

2008

2010

Year of Death

Ca

nce

r D

ea

ths

pe

r 1

00

,00

0 P

eo

ple

Source: National Cancer Institute

Progress Against Kidney Cancer

New Cases

6

8

10

12

14

16

18

1973

1975

1977

1979

1981

1983

1985

1987

1989

1991

1993

1995

1997

1999

2001

2003

2005

2007

2009

Year of Diagnosis

Ne

w C

an

cer

Ca

ses

pe

r 1

00

,00

0 P

eo

ple

Source: National Cancer Institute

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