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Definition: A respiratory stimulant is primarily used
in addition to noninvasive ventilation (Noninvasive
ventilation provides ventilatory support to a patient
through the upper airways)as a means to help
increase the urge to breathe. It works by stimulating
the central nervous system, resulting in an increase
in respiratory rate and tidal volume, which is the
amount of air that is inhaled or exhaled during a
normal breath
Respiratory stimulants
Respiratory stimulants
• Examples of respiratory stimulants include-
1.Doxapram, also known as Dopram, is a respiratory
stimulant and as such, helps stimulate or improve breathing.
Doxapram is used to help stimulate the respiratory drive in
patients who are recovering from surgery, who have overdosed
on certain drugs or, who have high carbon dioxide levels in
their blood, which can occur in COPD.
1.severe allergic reaction including rash, hives, itching,
shortness of breath, tightness in the chest, swelling of the
face, mouth, lips or tongue.
2.chest pain
3.heart rate changes or feeling like your heart skips a
beat
4.disorientation
5.fainting
6.fever
7.urination difficulties
8.severe dizziness, headache
9.inability to control the bladder
10.feeling hyperactive
11.muscle spasms12.seizures
Side Effects
2.Theophylline is a methylxanthine, a type
of bronchodilator used in COPD treatment to relax the
smooth muscles of the airway and suppress their
hyperresponsiveness to airway irritants.
Theophylline may be used in addition to COPD inhalers and
other medications, such as oral corticosteroids. It is most
commonly used to manage symptoms associated with COPD
and other respiratory ailments.
Theophylline levels should be monitored closely for signs of
toxicity, as toxicity may occur even when the drug levels are
within a therapeutic range.Theophylline should be used
cautiously in neonates, patients with cirrhosis of the liver, the
elderly, women in their third trimester of pregnancy, people
with peptic ulcer disease, heart arrhythmias (except when the
heart rate is too slow), and seizures.
Side Effects:
1. Allergic reaction, including severe itching, skin rash,
swelling of the face, lips or tongue
2nausea and vomiting
3rapid heartbeat, or feeling like your heart skips a beat
4dizziness
5fever
6seizures
3.Almitrine-It enhances respiration by acting as an
agonist of peripheral chemoreceptors located on the
carotid bodies. The drug increases arterial oxygen
tension while decreasing arterial carbon dioxide
tension in patients with chronic obstructive
pulmonary disease(COPD).