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433 Ophthalmology Team Refractive Errors
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Contentsoflecture
Physiology Inves0ga0ons Refrac0veerrors
Myopia
Hyperopia
As0gma0sm
Presbyopia
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Physiology-Tohaveaclearpictureintheretina&tobeseeninthebrain,thereshouldbeaclearcornea,clearanteriorchamber,clearlens,clearvitreouscavitythenthepictureshouldbefocusedontheretinawithnormalrefractiveindex.
-Theretinaisresponsiblefortheperceptionoflight.Itconvertslightraysintoimpulses;sentthroughtheopticnervetoyourbrain,wheretheyarerecognizedasimages.-Normalrefractivepoweroftheeyeis60diopters.(Thecorneaaccountsforapproximatelytwo-thirdsofthisrefractivepower(about40diopters)andthecrystallinelenscontributestheremaining)
-Thenormalaxiallengthis22.5mml(it’smeasuredfromthetipofthecorneatothesurfaceoftheretina)
-Iftheaxiallengthislonger=thepicturewillbeinfrontoftheretina
-Iftheaxiallengthisshorter=thepicturewillbebehindtheretina
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Refractions:
• Refractionindicatesthediopter,andthediopteristhefocalrateoflens.Themorerefractivepowerthelenshastheshorterthefocalpointwillbe.
• Inoptics,refractionoccurswhenlightwavestravel
fromamediumwithagivenrefractiveindextoamediumwithanother.Attheboundarybetweenthemedia,thewave'sphasevelocityisaltered,itchangesdirection.
• Theamountofbenddependsontherefractiveindexofthemediaandtheangleofincidence
• Therefractiveindexofamediumisdefinedastheratioofthephasevelocityofawavelightinareferencemediumtoitsvelocityinthemediumitself.
Unitofrefraction-ThepowerofthelensismeasuredbytheDiopter(D)Theunitofrefraction.
THEEYE’SOPTICALSYSTEM
• Cornea• Mainrefractingsurface(2/3rdthepoweroftheeye,40diopter)
• Thepowerofthecorneaisfixed,itreachesitsmaximumpowerattheageof18.That’swhyit’sNOTrecommendedtodoanyrefractivesurgerybeforeageof18.
**Attheageof40=theywillhavepresbyopia**Poweroflensattheageof60=0
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• Lens
• Thelensprovides20dioptersofrefractivepower.
• Therelaxedlens=20diopter.Inaccommodativestageitcanincreasetherefractivepowerupto15dmorelikeinchildren(withtimeitbecomesless)
• Accommodation• Emmetropic(normal)eye
Objectscloserthan6meterssenddivergentlightthatfocusbehindretina;adaptivemechanismofeyeistoincreaserefractivepowerbyaccommodation
• Helm---holtztheory• Whentheeyelookatcloseobject->Contraction
ofciliarymuscle------>decreasetensioninzonulefibers------>elasticityoflenscapsulemoldlensintosphericalshape------>greaterdiopticpower------>divergentraysarefocusedonretina
• contractionofciliarymuscleissuppliedbyparasympatheticthirdnerve
• Visualacuity(VA)• VAisthevitalsignoftheeyewithIOP(intraocularpressure).
• ToassesstheeffectofpathologyonVA.Youmusteliminatetheeffectofrefractiveerror.Thisisachievedbymeasuring:thepatient’sbestspectaclecorrectionorviewingthetestchartthroughapinhole.
• Thepinholeisusedtoeliminatethemildrefractiveerrorofthepatient.Thepinholewillcausemusclespasm.Pinholeglassestypicallyhaveaholediameterofabout1mmto1.2mm.Thepinholecorrectsforaboutthreediopters.
• Whenexaminingthepatientyoushouldexamineeacheyealone(andcovertheothereye)
Note:Afterprolonged
readingtheremightbeciliaryspasmassociated
headache
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• Aftervisualacuitydopinhole:√ Ifimproved20/20=>meansrefractiveerror√ Noimprovement=>othercauses√ Ifimprovedbut20/80=>refractiveerror+othercauses.
• Howtotestthevision• Centralvisualacuityo Displayofdifferent–sizedtargetsshownatastandarddistancefromtheeye.
• Inthefirst2monthsoflife:dolightobjectiontest(ifthebabyobjectingorclosingtheeyeinresponsetolightitmeanshe/sheisseeing)
• From2months–3years:dofollowandfixatetest.Atthisage,babieswillstarttofollowtheobjects,sobringatoyinfrontofthemanddothetest.(Iffollowingthetoy------>goodvision).ORyoucandoCSM“CentralSteadyMaintained”(central=seeingcentrally.Steady=nonystagmus.Maintained=babyisfollowingobject&afterblinkinghe/shecontinuesfollowingthesameobject)
• Age3–6years:Allen’schart• Morethan6years:Snellen’schart• Thevisionmaturationisacquiredskillforthebrain,sobabieswhenthey’refirstborntheywillbelegallyblind.
• Theaxiallengthoftheeyewillgrowquicklyinthefirst6months.Soifanythingstopsthegrowingtheywillhaveamblyopia(lazyeye)E.g:vitreoushemorrhage,congenitalcataract.
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Testingpoorvision• Ifthepatientisunabletoreadthelargestletter<(20/200)
• Movethepatientclosere.g.5/200
• Ifpatientcannotread:
o Countfingers(CF)o Handmotion(HM)o Lightperception(LP)ORNolightperception(NLP)Legalblindness:(heneedsassistance)Legalblindness:Thecriteriausedtodetermineeligibilityforgovernmentdisabilitybenefitsandwhichdonotnecessarilyindicateaperson'sabilitytofunction.IntheUS,thecriteriaforlegalblindnessare:*Visualacuityof20/200orworseinthebettereyewithcorrectivelenses.*Visualfieldrestrictionto20degreesdiameterorless(tunnelvision)inthebettereye.NotethatthedefinitionoflegalblindnessdiffersfromcountrytocountryandthatthecriterialistedabovearefortheUS.Testingnearvisualacuity
• Itisdoneatastandardworkingdistance~30---40cm
• Avarietyofchartsareavailable
Refractiveerrors
• Amismatchbetweentherefractivepowerandthefocusingdistanceoftheeye
• Inabilitytoseeclearlyisoftencausedbyrefractiveerrors.
• Threetypesofrefractiveerrors(Ametrpia)Myopia(nearsightedness),Hyperopia(farsightedness)andAstigmatism.• Emmetropia(normal)• Ametrpia=Refractiveerror
Whatdoes20/200mean?Itmeansthatthepatientseesat20feetwhatanormalpersoncouldseeat200feet
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1)Emmetropia• AdequatecorrelationORmatchingbetweenaxiallengthandrefractivepoweroftheeye• Raysoflightfromadistantobjectarebroughttoapinpointsharpfocusontheretina(noaccommodation).Allrefractiveerrorsaresomedeviationfromemmetropia.
2)Myopia• Raysoflightfromadistantobjectsconvergeinfrontoftheretina,causingablurredimageontheretina
• Myopescanseecloseobjectsclearly,myopiaiscommonlyknownas“near---sightedness”
• MostprevalentamongAsians(80---90%),followedby25%ofAfricanAmericansand13%ofCaucasians.
• Averageageofonset:8years• Etiology:notclear,geneticfactors
• Diabeticspatientshavebothmyopiaandhyperopiadependingonthelevelofthebloodsugar,thismeanstheirDMisnotcontrolled!!
v Causesofmyopia1.Increasedrefractivepower:a) Changeinlensnucleusorshape:cataract,spherophakia,diabetesb) Lensrepositioning:ciliarymuscleshifte.g.miotics.OrLensmovemente.g.anteriorlensdislocationc) Ciliarymuscletone*:excessiveaccommodatione.g.medicalstudents*Readingalotataneardistance.d) Increasecornealpower:keratoconus,congenitalglaucoma2.Increaseaxiallength:congenitalglaucoma,posteriorstaphyloma• Symptoms1. Blurreddistancevision2. Squintinanattempttoimproveuncorrectedvisualacuitywhengazingintothedistance3. Headacheduetoeyestrain.
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o MyopiaForms:–Benignmyopia(schoolagemyopia)• Onset8---12years,myopiaincreasesuntilthechildstopsgrowinginheight• Generallytapersoffatabout20yearsofage–Progressiveormalignantmyopia:(alsocalledDegenerativeorpathologicalmyopia)• Myopiaincreasesrapidlyeachyearandisassociatedwith,fluidityofvitreousandchorioretinalchange.
o Morphologiceyechangesinpathologicalmyopia:– Deepanteriorchamber– Atrophyofciliarymuscle– Vitreousmaycollapseprematurely–leadingtoopacification– Funduschanges:LossofpigmentinRPE(Retinalpigmentepithelium),largediscandwhitecrescent---shapedareaontemporalside,RPEatrophyinmaculararea,posteriorstaphyloma,andretinaldegeneration------>hole------>increaseriskofRRD(rhegmatogenousretinaldetachment).
o Myopiaiscorrectedby(negative)concavelenses.
3)Hyperopia• Raysoflightfromadistantobjectnowfocusbehindtheretina.•Hyperopicpeoplemustaccommodatewhengazingintodistancetobringfocalpointontotheretina•However,thisreducestheiraccommodativereservewhentheywanttoviewcloseobjects.Thismeanstheirdistancevisionisgenerallybetterthantheirnearvision,hencetheterm“long---sightedness”• Etiology:notclear,inherited,traumamaycausedislocationofthelensCausesofHyperopia1.Decreasedrefractivepoweroftheeye:
• Absent(aphakia)orposteriorlyrepositionedlens• Weakaccommodation:trauma,marijuana(marijuanacausesaweakaccommodationafterusingit)2.Decreasedeffectiveaxiallength(retinapushedforward):tumor,orbitalmass
Uncorrectedmyopiaanduncorrectedhyperopiainchildrenmightleadtoamblyopia(seelateranisometropia)
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Symptoms
• Visualacuityatneartendstoblurrelativelyearly‘’inabilitytoreadfineprint’’
• Asthenopicsymptoms:eyepain,headacheinfrontalregion.• Accommodativeesotropia:becauseaccommodationislinkedtoconvergenceleadingtoeasotropia.
Hyperopiaiscorrectedby(positive)convexlenses.
4)Astigmatism• Astigmatismisacommonandgenerallytreatableimperfectioninthecurvatureoftheeyethatcausesblurreddistanceandnearvision.
• Astigmatismoccurswheneitherthecorneaorthelens,hasmismatchedcurves.Insteadofhavingonecurvelikearoundball,thesurfaceiseggshaped.Thiscausesblurredvisionatalldistances.
• Inastigmatism,surfaceofcorneaisnothomogenous.Usuallyitiscongenital.
• Parallelrayscometofocusin2focallinesratherthanasinglefocalpoint
Causesofastigmatism
• Cornealcauses(majority):Simplecornealastigmatism,Keratoconus(causesMyopicastigmatism),Massese.g.lidtumor,Ptosis
• Lenticularcauses:Lensdislocation,lenticonus
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Symptoms
– Asthenopicsymptoms(headache,eyepain)– Blurredvision– Distortionofvision– Headtiltingandturning– Uncorrectedastigmatism>1.5Dioptersmightleadtoamblyopiainchildren
Classification–Regularastigmatism:(2meridians)powerandorientationofprinciplemeridiansareconstant.Theprincipalmeridiansare90degreesapart(perpendiculartoeachother).– Withtheruleastigmatism,Againsttheruleastigmatism,Obliqueastigmatism
–Irregularastigmatism:(differentmeridians)powerandorientationofprinciplemeridianschangeacrossthepupil.Theprincipalmeridiansarenotperpendicular.
Astigmatismiscorrectedbycylindricallenses
Anotherclassification:
Threeprimarytypesofastigmatism:
Myopicastigmatism:Oneorbothprincipalmeridiansoftheeyearenearsighted.
Hyperopicastigmatism:Oneorbothprincipalmeridiansarefarsighted.
Mixedastigmatism:Oneprinicipalmeridianisnearsighted,andtheotherisfarsighted.
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√ Cylindricallens=>tocorrectastigmatismwitheithermyopiaorhyperopia.
√ Biconcavelens=>tocorrectmyopia(-lens)√ Biconvexlens=>tocorrecthyperopia(+lens)
4)Presbyopia• AgerelatedPhysiologicallossofaccommodation• Depositionofinsolubleproteinsinthelenswithadvancingageleadstoprogressivedecreaseintheelasticityofthelensanddecreaseaccommodation.
• Around40yearsofage,accommodationbecomelessthan3D.readingispossibleat40-50cm->difficultlyreadingfineprint,headache,visualfatiguePresbyopiaiscorrectedbyconvexlenses
5)Anisometropia• Anisometropiaistheconditioninwhichthetwoeyeshaveunequalrefractivepower. Generallyadifferenceinpoweroftwodioptersormoreistheacceptedthresholdtolabeltheconditionanisometropia.
• Morethan3dioptersdifferenceifnotdetectedinpediatricsandcorrecteditcancauseunilateralamblyopia“intheweakereye”.
• Individualscantolerateupto2-3Dioptersofanisometropiabeforebecomingsymptomatic.
6)AniseikoniaAnocularconditioninwhichtheimageofanobjectinoneeyediffersinsizeorshapefromtheimageofthesameobjectintheothereye.
Ifthedifferencebetween2eyes:(D=Diopter)-Lessthan3D->it’soktowearglasses
-Morethan3butlessthan7D->patientcan’ttolerateglassesbutcanusecontactlenses
-Morethan7D->refractivesurgery
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Causes
-Correctionofarefractiveerror
-Anisometropia
-Antimetropia(beingmyopic(nearsighted)inoneeyeandhyperopic(farsighted)intheother.)
-Meridionalaniseikoniaoccurswhentheserefractivedifferencesonlyoccurinonemeridian(seeastigmatism).
-Refractivesurgery
v Typesofopticalcorrection
• Spectaclelenses
– Monofocallenses:sphericallenses,cylindricallenses
– Multifocallenses
• Contactlenses
–Higherqualityofopticalimageandlessinfluenceonthesizeofretinalimagethanspectaclelenses
–Indication:cosmetic,athleticactivities,occupational,irregularcornealastigmatism,highanisometropia,andcornealdisease
–Disadvantages:carefuldailycleaninganddisinfection.
–Complications:infectiouskeratitis,giantpapillaryconjunctivitis,cornealvascularization,andseverechronicconjunctivitis
v RefractivesurgeriesA. Keratorefractivesurgery:(workonthecornea.Doesn’tcorrect
highpower)• Refractivesurgery–flattenscornealsurfaceformyopiaorincreasesit’scurvatureinHyperopia.
• Improvesunaidedvisualacuitybutmayhavecomplications
• Examples:PRK,LASIK,LASEK,EPILASIK
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B. Intraocular surgery: for high power
• Givebestopticalcorrectionforaphakia;avoidsignificantmagnificationanddistortioncausedbyspectaclelenses.
• Clearlensextraction.• PhakicIOL( intraocular lenses): lensesmadeofplasticorsiliconethatareimplantedintotheeyepermanentlytoreduceaperson'sneedforglassesorcontactlenses.
• Oneofthesideeffectsofintraocularlensprocedure=>lossofaccommodation.
Photorefractivekeratectomy(PRK)
(noflap.Wejustremovetheepithelium applylaser thentheepitheliumwillgrow)
Advantages:saferonthelongrun
Disadvantages:severepainfor1week,blurredvisionfor2 3weeks
laser-assisted-in-situkeratomileusis(LASIK)(thinflap)
Advantages:immediate20/20vision,nopain,goodvisualrehabilitation,cancorrecthighnumbers(upto–8)
Disadvantages:severetrauma theflapcanfalldown
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MCQ
1.AladywantsLASIKsurgeryforherdaughter.Sheasksforyouropinion.AllthefollowingthingsaresuitableforperformingLASIKexcept:A. Myopiaof4Diopters.B. Ageof15years.C. Stablerefractionfor1year.D. Cornealthicknessof600microns
2. Inmyopia:A. LengthofeyeballisshortB. ImageformsinfrontofretinaC. LensislesssphericalD. Patientcanseefarobjectsclearly
3. ThemostcommoncauseofreducedvisionintheworldisA. TrachomaB. DiabeticretinopathyC. RefractiveerrorsD. Glaucoma
Answers:1-B2-B3-C
CONTRAINDICATIONSofLASIK(source:http://lessons4medicos.blogspot.com/2008/09/mcqs---opthalmology.html)
Unstablerefractiveerror.
Agelessthan21years.
Activecollagenvasculardisease(especiallyinthepresenceofiritisorscleritis).
Pregnancy.
Presenceofapacemaker.
Anyongoingactiveinflammationoftheexternaleye(eg,conjunctivitis,severedryeye).
Refractiveerroroutsidetherangeoflasercorrection.
Keratoconus