The intelligent coater for innovative solutions
Sub-Kilogram Scale Benchtop Tablet Coater
Patent Pending
Choose the original…choose success!
INNOVATION•Coatverysmallquantitiesofcores–as few as
100 tablets•Exchangeablecoatingunitwithintegratedcoating
chamber, drum, plenum and front process port•Completeseparationofproductcontactareafrom
mechanical space•Integratedworkspaceforsolutionvessel,mixer
and scale•Closedtransfersoroff-benchloading/unloading
under containment
VERSATILITY•Aqueousfilmandsolventcoatingprocesses•Functionalandmodifiedreleasecoatings•Coatingwithoneormoredruglayers•Tablets,mini-tabsandsoftgels•Optionalexecutionforhandlingpotent
compounds
FUNCTIONALITY•Fullyperforateddrumwithanti-slidebars•Schlickspraynozzlewithanti-beardingcap•Exhausttemperaturesetpointcontrol•Independentcontrolofatomizingandpatternair•Externalspraynozzlepositioningwithcoater
door closed•Drumcapacityis5liters
USABILITY•24x36inchfootprint-fitsneatlyonstandard
laboratory bench•10-inchcolortouchscreenHMI•Frontaccessmanualsampling•Excellentvisibilitythroughfrontwindow•Easydisassemblyforcleaningatthebenchor
out-of-place•Benchtoporcart-mountedformobileapplications
At last, the wait is over… here is the benchtop coater you asked for! Inspired by our customers, and driven by innovation, Thomas Engineering presents the FLEX 05 benchtop tablet coater!
FLEX 05 is more than just a film coater – it is a practical and highly functional coating platform for most processes including
those where high weight-gain drug layers and modified release coatings are essential.
TheFLEX05coaterincludescomputer-basedcontrols,dataacquisitionandreportingfunctionsinacompactpackagewith
color touch screen HMI. Convenient and versatile, the FLEX 05 is sure to become your indispensable coater for rapid product
development, feasibility studies, and production of early stage clinical supplies – even with just a handful of tablets!
Patent Pending.Illustrations, specifications
and technical data are subject to change without notice.
Some features described in this document are optional.
FLEX 05…because tomorrow takes place on your benchtop today
Just Plug ‘n’ Process!
The FLEX 05 is an integrated tablet coating system – Tablet coating
chamber with drum and exhaust plenum, process air handling, solution
delivery and controls - in a single benchtop unit!
Operator Protection and Containment
Innovative Exchangeable Coating Unit (XCU)
Attention to Details
•FLEX05coatingplatformwithexchangeable coating units – drum, chamber, plenum and process port
•XCUisself-connectingtotheinlet/exhaust air ports and to drum drive
•Easyremovalandinstallationforfastsetups and changeovers without tools
•Integratedexhaustplenumextractswith the XCU for easy cleaning
•XCUsareinterchangeable–dedicatecoating units to drug compound families, research departments and formulation scientist groups
FLEX 05 is thoughtfully designed with the user in mind•Accurateandrepeatablegun
positioning - no other manual adjustments!
•Veryfewpartstohandleduringcleanings and project transitions
•Tool-lesssetupsandchangeovers•Convenientworkspaceforsolution
vessel, mixer and scale•Compellingaesthetics
•Coateroperatesundernegativepressure•Inflatablesealonfrontprocessport•Sanitaryflangesavailableforclosed
loading and unloading•Manualsamplingandspraynozzle
positioning with front process port closed
•Fullycontainedexecutionwithsafechange filters
One Coating Platform - Many Uses
Solution Delivery
HMI and Controls
• Processparametersaresetusingcolortouch screen HMI
• HMI-drivenmanualcontroloftheprocess with data capture
• Minimumnumberofcontrolscreensfor ease of use
• Realtimedisplayofmeasuredprocessparameters
• RealtimecalculationanddisplayofEnvironmentalEquivalency(EE)Factor using proprietary TAAC process modeling algorithm
•Peristalticpumpwithpreciseflowcontrol
•Schlick®anti-beardingspraynozzle (ABC technology) provides performance matching nozzles on production scale coaters
•Vibration-dampenedscaleforaccurate flow rate measurement
•Externalmanualpositioningofspraynozzle with coater door closed
•Nozzlepositioningmechanismwith graduated scale for repeatable nozzle-to-bed distance and angle settings
•ExchangeableCoatingUnits(XCUs)permit the FLEX 05 to be easily shared between multiple user groups
•FLEX05isacosteffectivealternativeto purchasing multiple conventional-type lab coating systems
FLEX 05…because tomorrow takes place on your benchtop today
Just Plug ‘n’ Process!
The FLEX 05 is an integrated tablet coating system – Tablet coating
chamber with drum and exhaust plenum, process air handling, solution
delivery and controls - in a single benchtop unit!
Patent Pending.Illustrations, specifications
and technical data are subject to change without notice.
Some features described in this document are optional.
Overall dimensions 24” x 36” x 30” high [610 mm x 815 mm x 760 mm]
Up to 5 liters; ½ liter with divider plate
12 in. [305 mm]
5 – 40 RPM
20 – 100 CFM (45°C maximum bed temp) [35 – 170 m3/h]
Schlick™ 970 ABC
Watson-Marlow peristaltic pump
20 – 30 psi at 4 SCFM [1.4 – 2.0 bar at 7 m3/h]
PLC and touch panel HMI
80 - 100 psi [5.4 – 6.8 bar]
230 VAC, 60 Hz, single phase; 30 amps
280 lbs. with Exchangeable Coating Unit [130 kg]240 lbs without Exchangeable Coating Unit [110 kg] The Exchangeable Coating Unit can be removed from the coating platform to be cleaned in a lab sink, in a parts washer or in a cleaning room
Drum volume
Drum diameter
Drum speed
Air flow and temperature
Spray nozzle
Solution delivery
Atomizing/Pattern air
Controls
Compressed air supply
Electrical
Weight
Cleaning
Patent Pending.Illustrations, specifications
and technical data are subject to change without notice.
Some features described in this document are optional.
INTEGRATED COATING SYSTEM•Coatingchamberwithdrumandexhaustplenum,processairhandling,solutiondeliveryandcontrols
in a single benchtop unit•Minimumspacerequirement–fitsonmostexistinglaboratorybenches•Built-inworkspaceforsolutionvesselandmixer•Single-pointconnectionsforelectricandcompressedairutilities
USER FRIENDLY•Simpletouchscreengraphicsforintuitivereferencetocoatingdevices•Singleprocesscontrolwindowfortheparametersandmeasurements•Easypositioningofspraynozzlewithouttoolsandwithoutopening
front process port•Easytouse–reducestrainingtimeandexpense
PROPRIETARY THOMAS TAAC PROGRAM•Builtintothecoaterforreal-timeassessmentofdryingconditions•Providesassistanceforprocessscale-upcalculations
PROCESS VERSATILITY•Provides“futuresafety”–helpsaccommodatenewprocessesnotyetinthedevelopmentpipeline
Features and Benefits
OptionsHEPA Filtration•Inlet and exhaust,
remote
Instrumentation upgrade package•Additional instruments
to measure inlet dew point, bed temperature and ΔP through bed
Solvent coating•Execution for Class 1,
Division 2
Containment• Operator protection
(inflatable seals) and fully contained execution with safe change filters
Drums and XCUs• Additional drums and
Exchangeable Coating Units (XCUs) are also available
FLEX 05 Specifications
Capabilities For more than 50 years, Thomas Engineering has been a partner in the solid dosage processing industry, helping customers
develop and manufacture pharmaceutical products in an efficient and cost effective manner.
With the Accela-Cota® FLEX 05, Thomas can help even more by offering an integrated tablet coating platform for small-scale
development of a range of coating processes. With the FLEX 05, our customers have an innovative tool to succeed in developing
coated products rapidly in response to market demands for new and improved drug therapies. Our customers appreciate the value of a partnership with Thomas Engineering, the market leader dedicated to coating, tablet
compression and tablet press tooling. These customers know that their investment extends beyond a system of machines and
controls – they also benefit from our expertise and competency resulting from decades of experience with tablet coating systems
in the field. The dividend is their assurance that their TEI coating system will deliver reliable performance and consistently good
finished products for many years.
Choose the original…choose success…choose Thomas Engineering.
Thomas Engineering Inc.575 West Central Road
Hoffman Estates, IL 60192T. 847/358-5800 F. 847/358-5817
www.thomaseng.com
FLEX 500
Spray technology
Patent Pending.Illustrations, specifications
and technical data are subject to change without notice.
Some features described in this document are optional.
Compu-Lab
Accela-Cota Tablet Press Tooling
Continuous Tablet Coater
Production class tablet coater with exchangeable drums, optimized design for enhanced cleanability and with features for manufacturing flexibility and process versatility. FLEX 500 is a winner of the prestigious iF Product Design Award 2010 for outstanding quality in design.
Innovative designs for process versatility
Integrated tablet coating system for R&D, pilot plant, clinical supplies and small batch manufacturing
Production class tablet coater with more than 1,200 installations world wide
Leader in the design and manufacture of punch and die tooling.
High throughput continuous processing for tablets and softgels