Front MatterSource: Proceedings of the National Academy of Sciences of the United States of America,Vol. 94, No. 15 (Jul. 22, 1997), pp. i-viiiPublished by: National Academy of SciencesStable URL: http://www.jstor.org/stable/42742 .
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PROCEEDINGS
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NATIONAL ACADEMY OF SCIENCES
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July 22, 1997
Volume 94/ Number 15
INCLUDES: PAPERS FROM A NATIONAL ACADEMY OF SCIENCES COLLOQUIUM ON GENETICS AND THE ORIGIN OF SPECIES
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PROCEEDINGS
OF THE
NATIONAL ACADEMY OF SCIENCES
OF THE UNITED STATES OF AMERICA
July 22, 1997 Volume 94, Number 15 pp. 7691-8272
Table of Contents
Papers from a National Academy of Sciences Colloquium on Genetics and the Origin of Species
Genetics and the origin of species: An introduction 7691-7697 Francisco J. Ayala and Walter M. Fitch
Origin of Genes 7698-7703 Walter Gilbert, Sandro J. de Souza, and Manyuan Long
Transposable elements as sources of variation in 7704-7711 animals and plants
Margaret G. Kidwell and Damon Lisch
Long term trends in the evolution of H(3) HAI 7712-7718 human influenza type A
Walter M. Fitch, Robin M. Bush, Catherine A. Bender, and Nancy J. Cox
Genes, peoples, and languages 7719-7724 L. Luca Cavalli-Sforza
DNA variation at the Sod locus of Drosophila 7725-7729 melanogaster: An unfolding story of natural selection
Richard R. Hudson, Alberto G. Saez, and Francisco J. Ayala
Neutral behavior of shared polymorphism 7730-7734 Andrew G. Clark
Divergent and conserved features in the spatial 7735-7741 expression of the Drosophila pseudoobscura esterase-5B gene and the esterase-6 gene of Drosophila melanogaster
Natalia A. Tamarina, Michael Z. Ludwig, and Rollin C. Richmond
A demographic approach to selection 7742-7747 Wyatt W. Anderson and Takao K. Watanabe
Phylogenetics and the origin of species 7748-7755 John C. Avise and Kurt Wollenberg
Assortative fertilization in Drosophila 7756-7760 Therese Ann Markow
Incipient species formation in salamanders of the 7761-7767 Ensatina complex
David B. Wake
Genetics and the origin of bird species 7768-7775 Peter R. Grant and B. Rosemary Grant
Vagaries of the molecular clock 7776-7783 Francisco J. Ayala
Evolution of codon usage bias in Drosophila 7784-7790 Jeffrey R. Powell and Etsuko N. Moriyama
The evolution of plant nuclear genes 7791-7798 Michael T. Clegg, Michael P. Cummings, and Mary L. Durbin
iii
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Contents
Evolution by the birth-and-death process in multigene 7799-7806 families of the vertebrate immune system
Masatoshi Nei, Xun Gu, and Tatyana Sitnikova
Perspective
The radioactivity of atmospheric krypton in 7807-7810 1949-1950
Anthony Turkevich, Lester Winsberg, Howard Flotow, and Richard M. Adams
Review
Immunity to retroviral infection: The Friend 7811-7816 virus model
Kim J. Hasenkrug and Bruce Chesebro
Physical Sciences
APPLIED MATHEMATICS
Structure of the zero-pressure-gradient turbulent 7817-7819 boundary layer
G. I. Barenblatt, A. J. Chorin, 0. H. Hald, and V. M. Prostokishin
APPLIED PHYSICAL SCIENCES
Phosphorylation and subunit organization of axonal 7820-7824 neurofilaments determined by scanning transmission electron microscopy
R. D. Leapman, P. E. Gallant, T. S. Reese, and S. B. Andrews
CHEMISTRY
Inducible gene expression and protein translocation 7825-7830 using nontoxic ligands identified by a mammalian three-hybrid screen
Stephen D. Liberles, Steven T. Diver, David J. Austin, and Stuart L. Schreiber
Virtual combinatorial libraries: Dynamic generation of 8272 molecular and supramolecular diversity by self-assembly (Correction)
Ivan Huc and Jean-Marie Lehn
Biological Sciences
BIOCHEMISTRY
Association of the mammalian helicase MAH with the 7831-7836 pre-mRNA splicing complex
Gyongyi M. Molnar, Anne Crozat, Stine-Kathrein Kraeft, Qing Ping Dou, Lan Bo Chen, and Arthur B. Pardee
Helical repeat of DNA in the region 7837-7840 of homologous pairing
Konstantin Kiianitsa and Andrzej Stasiak
Allosteric intermediates indicate R2 is the liganded 7841-7844 hemoglobin end state
Maria A. Schumacher, Ekaterina E. Zheleznova, Kitty S. Poundstone, Ronald Kluger, Richard T. Jones, and Richard G. Brennan
Total chemical synthesis of enzymatically active 7845-7850 human type II secretory phospholipase A2
Tilman M. Hackeng, Carine M. Mounier, Cassian Bon, Philip E. Dawson, John H. Griffin, and Stephen B. H. Kent
A DnaB intein in Rhodothermus marinus: Indication 7851-7856 of recent intein homing across remotely related organisms
Xiang-Qin Liu and Zhuma Hu
X-ray structures of a hydrolytic antibody and of 7857-7861 complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release
Benoit Gigant, Jean-Baptiste Charbonnier, Zelig Eshhar, Bernard S. Green, and Marcel Knossow
Direct involvement of the ubiquitin-conjugating 7862-7867 enzyme Ubc9/Hus5 in the degradation of IKBa
Kei Tashiro, Matthew P. Pando, Yumi Kanegae, Penny M. Wamsley, Satoshi Inoue, and Inder M. Verma
The p53 tumor suppressor targets a novel regulator of 7868-7872 G protein signaling
Leonard Buckbinder, Susana Velasco-Miguel, Yan Chen, Ningzhi Xu, Randy Talbott, Larry Gelbert, Jizong Gao, Bernd R. Seizinger, J. Silvio Gutkind, and Nikolai Kley
Human and Saccharomyces cerevisiae dolichol 7873-7878 phosphate mannose synthases represent two classes of the enzyme, but both function in Schizosaccharomyces pombe
Paul A. Colussi, Christopher H. Taron, Jamey C. Mack, and Peter Orlean
Steroid receptor induction of gene transcription: A 7879-7884 two-step model
Guido Jenster, Thomas E. Spencer, Mark M. Burcin, Sophia Y. Tsai, Ming-Jer Tsai, and Bert W. O'Malley
a-Tocopheryl hydroquinone is an efficient 7885-7890 multifunctional inhibitor of radical-initiated oxidation of low density lipoprotein lipids
Jiri Neuzil, Paul K. Witting, and Roland Stocker
The herpes simplex virus 1 protein kinase Us3 is 7891-7896 required for protection from apoptosis induced by the virus
Rosario Leopardi, Charles Van Sant, and Bernard Roizman
The major yeast poly(A)-binding protein is associated 7897-7902 with cleavage factor IA and functions in premessenger RNA 3'-end formation
Lionel Minvielle-Sebastia, Pascal J. Preker, Thomas Wiederkehr, Yvan Strahm, and Walter Keller
iv
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Contents
Leishmania tarentolae contains distinct cytosolic and 7903-7908 mitochondrial glutaminyl-tRNA synthetase activities
Christoph E. Nabholz, Remy Hauser, and Andre Schneider
Activation of the orphan receptor RIP14 by retinoids 7909-7914 Ann Marie Zavacki, Jiirgen M. Lehmann, Wongi Seol, Timothy M. Willson, Steven A. Kliewer, and David D. Moore
The Xenopus proglucagon gene encodes novel 7915-7920 GLP-1-like peptides with insulinotropic properties
David M. Irwin, Malathy Satkunarajah, Yi Wen, Patricia L. Brubaker, Raymond A. Pederson, and Michael B. Wheeler
Targeted inactivation of ai2 or ai3 disrupts activation 7921-7926 of the cardiac muscarinic K+ channel, IK+Ach, in intact cells
Margaret 0. Sowell, Chianping Ye, Dennis A. Ricupero, Sherry Hansen, Stephen J. Quinn, Peter M. Vassilev, and Richard M. Mortensen
BIOPHYSICS
Detection of single-molecule interactions using 7927-7931 correlated thermal diffusion
A. D. Mehta, J. T. Finer, and J. A. Spudich
Nonexponential kinetics of a single tRNAPhe molecule 7932-7936 under physiological conditions
Yiwei Jia, Alexander Sytnik, Liangquan Li, Serguei Vladimirov, Barry S. Cooperman, and Robin M. Hochstrasser
Microsecond atomic force sensing of protein 7937-7941 conformational dynamics: Implications for the primary light-induced events in bacteriorhodopsin
Itay Rousso, Edward Khachatryan, Yahaloma Gat, Igor Brodsky, Michael Ottolenghi, Mordechai Sheves, and Aaron Lewis
Kinetic theory of fibrillogenesis of amyloid ,3-protein 7942-7947 Aleksey Lomakin, David B. Teplow, Daniel A. Kirschner, and George B. Benedek
CELL BIOLOGY
Phosphorylation and subunit organization of axonal 7820-7824 neurofilaments determined by scanning transmission electron microscopy
R. D. Leapman, P. E. Gallant, T. S. Reese, and S. B. Andrews
Inducible gene expression and protein translocation 7825-7830 using nontoxic ligands identified by a mammalian three-hybrid screen
Stephen D. Liberles, Steven T. Diver, David J. Austin, and Stuart L. Schreiber
Nuclear localization of basonuclin in human 7948-7953 keratinocytes and the role of phosphorylation
Shiro luchi and Howard Green
Tumor induction by a transformation-defective 7954-7958 polyoma virus mutant blocked in signaling through Shc
Roderick Bronson, Clyde Dawe, John Carroll, and Thomas Benjamin
Transmembrane/cytoplasmic domain-mediated 7959-7964 membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion
Hirokazu Nakahara, Linda Howard, Erik W. Thompson, Hiroshi Sato, Motoharu Seiki, Yunyun Yeh, and Wen-Tien Chen
The Schizosaccharomyces pombe spindle checkpoint 7965-7970 protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex
Xiangwei He, Thomas E. Patterson, and Shelley Sazer
Roles of phospholipase C /32 in chemoattractant- 7971-7975 elicited responses
Huiping Jiang, Yanan Kuang, Yanping Wu, Wei Xie, Melvin I. Simon, and Dianqing Wu
DEVELOPMENTAL BIOLOGY
An upstream, DNase I hypersensitive region of the 7976-7981 hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice
Michael A. McDevitt, Yuko Fujiwara, Ramesh A. Shivdasani, and Stuart H. Orkin
An important developmental role for oligosaccharides 7982-7986 during early embryogenesis of cyprinid fish
Jeroen Bakkers, Carlos E. Semino, Henri Stroband, Jan W. Kijne, Phillips W. Robbins, and Herman P. Spaink
EVOLUTION
Phylogeny of the genus Pistacia as determined from 7987-7992 analysis of the chloroplast genome
Dan E. Parfitt and Maria L. Badenes
An upper dentition of Aframonius dieides (Primates) 7993-7996 from the Fayum, Egyptian Eocene
Elwyn L. Simons and Ellen R. Miller
Functional and nonfunctional mutations distinguished 7997-8000 by random recombination of homologous genes
Huimin Zhao and Frances H. Arnold
Cleavage patterns and the topology of the metazoan 8001-8005 tree of life
James W. Valentine
Molecular evidence that echiurans and 8006-8009 pogonophorans are derived annelids
Damhnait McHugh
GENETICS
Cloning and characterization of hOGGl, a human 8010-8015 homolog of the OGG1 gene of Saccharomyces cerevisiae
J. Pablo Radicella, Claudine Dherin, Chantal Desmaze, Maurice S. Fox, and Serge Boiteux
v
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Contents
Molecular cloning and functional expression of a 8016-8020 human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase
Teresa Roldan-Arjona, Ying-Fei Wei, Kenneth C. Carter, Arne Klungland, Catherine Anselmino, Rui-Ping Wang, Meena Augustus, and Tomas Lindahl
Isolation of full-length ATM cDNA and correction of 8021-8026 the ataxia-telangiectasia cellular phenotype
Ning Zhang, Philip Chen, Kum Kum Khanna, Shaun Scott, Magtouf Gatei, Sergei Kozlov, Dianne Watters, Kevin Spring, Tim Yen, and Martin F. Lavin
Transitions in the coupling of transcription and 8027--8032 nucleotide excision repair within RNA polymerase II-transcribed genes of Saccharomyces cerevisiae
Marcel Tijsterman, Richard A. Verhage, Pieter van de Putte, Judith G. Tasseron-de Jong, and Jaap Brouwer
The one ancestor per generation rule and three other 8033-8035 rules of mitochondrial inheritance
Susumu Ohno
Synergistic and promoter-selective activation of 8036-8041 transcription by recruitment of transcription factors TFIID and TFIIB
Eduardo Gonzalez-Couto, Natacha Klages, and Michel Strubin
Retention of replication fidelity by a DNA polymerase 8042-8046 functioning in a distantly related environment
Holly Kloos Dressman, Chien-Chia Wang, Jim D. Karam, and John W. Drake
Fusion genes resulting from alternative chromosomal 8047-8051 translocations are overexpressed by gene-specific mechanisms in alveolar rhabdomyosarcoma
Richard J. Davis and Frederic G. Barr
High genetic instability of heterochromatin after 8052-8057 transposition of the LINE-like I factor in Drosophila melanogaster
Patrizio Dimitri, Bruno Arca, Libera Berghella, and Elisabetta Mei
The hotspot conversion paradox and the evolution of 8058-8063 meiotic recombination
Alan Boulton, Richard S. Myers, and Rosemary J. Redfield
IMMUNOLOGY
Direct delivery of exogenous MHC class I 8064-8069 molecule-binding oligopeptides to the endoplasmic reticulum of viable cells
Patricia M. Day, Jonathan W. Yewdell, Angel Porgador, Ronald N. Germain, and Jack R. Bennink
A single peripheral CD8+ T cell can give rise to 8070-8075 progeny expressing type 1 and/or type 2 cytokine genes and can retain its multipotentiality through many cell divisions
Anne Kelso and Penny Groves
Ku7O-deficient embryonic stem cells have increased 8076-8081 ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination
Yansong Gu, Shengfang Jin, Yijie Gao, David T. Weaver, and Frederick W, Alt
Identification of immunodominant T cell epitopes of 8082-8087 human glutamic acid decarboxylase 65 by using HLA-DR(a1 *0101,31 *0401) transgenic mice
Salil D. Patel, Andrew P. Cope, Mauro Congia, Teddy T. Chen, Eugene Kim, Lars Fugger, Diane Wherrett, and Grete Sonderstrup-McDevitt
Natural killer cell acceptance of H-2 mismatch bone 8088-8092 marrow grafts in transgenic mice expressing HLA-Cw3 specific killer cell inhibitory receptor (CD158b)
Anna Cambiaggi, Christophe Verthuy, Philippe Naquet, FranGois Romagne, Pierre Ferrier, Roberto Biassoni, Alessandro Moretta, Lorenzo Moretta, and Eric Vivier
Characterization of tumor necrosis 8093-8098 factor-deficient mice
Michael W. Marino, Ashley Dunn, Dianne Grail, Melissa Inglese, Yuji Noguchi, Elizabeth Richards, Achim Jungbluth, Hisashi Wada, Malcolm Moore, Barbara Williamson, Sunanda Basu and Lloyd J. Old
MEDICAL SCIENCES
Manipulation of T cell costimulatory and inhibitory 8099-8103 signals for immunotherapy of prostate cancer
Eugene D. Kwon, Arthur A. Hurwitz, Barbara A. Foster, Christopher Madias, Andrew L. Feldhaus, Norman M. Greenberg, Maurice B. Burg, and James P. Allison
Hypoxia-inducible factor-I modulates gene expression 8104-8109 in solid tumors and influences both angiogenesis and tumor growth
P. H. Maxwell, G. U. Dachs, J. M. Gleadle, L. G. Nicholls, A. L. Harris, I. J. Stratford, 0. Hankinson, C. W. Pugh, and P. J. Ratcliffe
Modified cytokeratins expressed on the surface of 8110-8115 carcinoma cells undergo endocytosis upon binding of human monoclonal antibody and its recombinant Fab fragment
Henrik J. Ditzel, Ursula Garrigues, Claus B. Andersen, Morten K. Larsen, H. Jacques Garrigues, Arne Svejgaard, Ingegerd Hellstr6m, Karl Erik Hellstr6m, and Jens C. Jensenius
Tat protein induces self-perpetuating permissivity for 8116-8120 productive HIV-1 infection
Chiang J. Li, Yutaka Ueda, Bin Shi, Laura Borodyansky, Lili Huang, You-Zhi Li, and Arthur B. Pardee
Transgenic Gagq overexpression induces cardiac 8121-8126 contractile failure in mice
Drew D. D'Angelo, Yoshihito Sakata, John N. Lorenz, Gregory P. Boivin, Richard A. Walsh, Stephen B. Liggett, and Gerald W. Dorn II
vi
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Contents
Macrophages lacking scavenger receptor A show a 8127-8131 decrease in binding and uptake of acetylated low-density lipoprotein and of apoptotic thymocytes, but not of oxidatively damaged red blood cells
Valeska Terpstra, Nonna Kondratenko, and Daniel Steinberg
Altered expression of the WT1 Wilms tumor 8132-8137 suppressor gene in human breast cancer
Gary B. Silberstein, Katharine Van Horn, Phyllis Strickland, Charles T. Roberts, Jr., and Charles W. Daniel
Mouse model of GM2 activator deficiency manifests 8138-8143 cerebellar pathology and motor impairment
Yujing Liu, Alexander Hoffmann, Alexander Grinberg, Heiner Westphal, Michael P. McDonald, Katherine M. Miller, Jacqueline N. Crawley, Konrad Sandhoff, Kinuko Suzuki, and Richard L. Proia
Thymineless death in colon carcinoma cells is 8144-8149 mediated via Fas signaling
Janet A. Houghton, Franklin G. Harwood, and David M. Tillman
The antisense bcl-2-IgH transcript is an optimal target 8150-8155 for synthetic oligonucleotides
Susanna Morelli, Domenico Delia, Sergio Capaccioli, Alessandro Quattrone, Nicola Schiavone, Anna Bevilacqua, Silvia Tomasini, and Angelo Nicolin
Growth arrest of Epstein-Barr virus immortalized B 8156-8161 lymphocytes by adenovirus-delivered ribozymes
Shuang Huang, Dwayne Stupack, Patricia Mathias, Yibing Wang, and Glen Nemerow
The CAG repeat within the androgen receptor gene 8272 and its relationship to prostate cancer (Correction)
Edward Giovannucci, Meir J. Stampfer, Krishna Krithivas, Myles Brown, Adam Brufsky, James Talcott, Charles H. Hennekens, and Philip W. Kantoff
MICROBIOLOGY
The hepatitis B virus X gene induces p53-mediated 8162-8167 programmed cell death
Paolo Chirillo, Sabrina Pagano, Gioacchino Natoli, Pier Lorenzo Puri, Vito Lelio Burgio, Clara Balsano, and Massimo Levrero
Gene expression from plasmids containing the 8168-8172 araBAD promoter at subsaturating inducer concentrations represents mixed populations
Deborah A. Siegele and James C. Hu
NEUROBIOLOGY
Acetylcholinesterase-transgenic mice display 8173-8178 embryonic modulations in spinal cord choline acetyltransferase and neurexin 1f3 gene expression followed by late-onset neuromotor deterioration
Christian Andres, Rachel Beeri, Alon Friedman, Efrat Lev-Lehman, Sivan Henis, Rina Timberg, Moshe Shani, and H-ermona Soreq
Intracisternal basic fibroblast growth factor enhances 8179-8184 functional recovery and up-regulates the expression of a molecular marker of neuronal sprouting following focal cerebral infarction
Takakazu Kawamata, W. Dalton Dietrich, Timothy Schallert, Jeffrey E. Gotts, Robert R. Cocke, Larry I. Benowitz, and Seth P. Finklestein
Expression and activation of SH2/PTB-containing 8185-8190 ShcA adaptor protein reflects the pattern of neurogenesis in the mammalian brain
Luciano Conti, Claudio De Fraja, Massimo Gulisano, Enrica Migliaccio, Stefano Govoni, and Elena Cattaneo
Brain-derived neurotrophic factor rapidly enhances 8191-8195 phosphorylation of the postsynaptic N-methyl-D-aspartate receptor subunit 1
Piin-Chau Suen, Kuo Wu, Eric S. Levine, Howard T. J. Mount, Jia-Ling Xu, Siang-Yo Lin, and Ira B. Black
Disruption of hippocampal development in vivo by 8196-8201 CR-50 mAb against Reelin
Kazunori Nakajima, Katsuhiko Mikoshiba, Takaki Miyata, Chikako Kudo, and Masaharu Ogawa
Fixation of allosteric states of the nicotinic 8202-8207 acetylcholine receptor by chemical cross-linking
Anke Watty, Christoph Methfessel, and Ferdinand Hucho
Interaction between amyloid precursor protein and 8208-8213 presenilins in mammalian cells: Implications for the pathogenesis of Alzheimer disease
Weiming Xia, Jimin Zhang, Ruth Perez, Edward H. Koo, and Dennis J. Selkoe
Opioid receptors from a lower vertebrate (Catostomus 8214-8219 commersoni): Sequence, pharmacology, coupling to a G-protein-gated inward-rectifying potassium channel (GIRKI), and evolution
Mark G. Darlison, Florian R. Greten, Robert J. Harvey, Hans-Jiirgen Kreienkamp, Thorsten Stiihmer, Henk Zwiers, Karl Lederis, and Dietmar Richter
PHARMACOLOGY
Functionally differentiating two neuronal nitric oxide 8220-8225 synthase isoforms through antisense mapping: Evidence for opposing NO actions on morphine analgesia and tolerance
Yuri A. Kolesnikov, Ying-Xian Pan, Anna-Marie Babey, Subash Jain, Roger Wilson, and Gavril W. Pasternak
Nitrergic control of peripheral sympathetic responses 8226-8231 in the human corpus cavernosum: A comparison with other species
Selim Cellek and Salvador Moncada
Quantitative trait loci controlling halothane sensitivity 8232-8237 in Caenorhabditis elegans
Bruno van Swinderen, David R. Shook, Robert H. Ebert, Vera A. Cherkasova, Thomas E. Johnson, Robert J. Shmookler Reis, and C. Michael Crowder
vii
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Contents
PHYSIOLOGY
Specific requirement of putrescine for the mitogenic 8238-8242 action of juvenile hormone on adult insect neuroblasts
Myriam Cayre, Colette Strambi, Pierre Charpin, Roger Augier, and Alain Strambi
PLANT BIOLOGY
AtMRPl gene of Arabidopsis encodes a glutathione 8243-8248 S-conjugate pump: Isolation and functional definition of a plant ATP- binding cassette transporter gene
Yu-Ping Lu, Ze-Sheng Li, and Philip A. Rea
Cloning of a polycistronic cDNA from tomato 8249-8254 encoding y-glutamyl kinase and y-glutamyl phosphate reductase
Mario Garcia-Rios, Tomomichi Fujita, P. Christopher LaRosa, Robert D. Locy, Jean M. Clithero, Ray A. Bressan, and Laszlo N. Csonka
Inheritance, gene expression, and lignin 8255-8260 characterization in a mutant pine deficient in cinnamyl alcohol dehydrogenase
John J. MacKay, David M. O'Malley, Timothy Presnell, Fitzgerald L. Booker, Malcolm M. Campbell, Ross W. Whetten, and Ronald R. Sederoff
Nontarget DNA sequences reduce the transgene 8261-8266 length necessary for RNA-mediated tospovirus resistance in transgenic plants
Sheng-Zhi Pang, Fuh-Jyh Jan, and Dennis Gonsalves
Social Sciences
PSYCHOLOGY
Integration of local pattern elements into a global 8267-8271 shape in human vision
Jukka Saarinen, Dennis M. Levi, and Bridgitte Shen
AUTHOR INDEX ix-xi
INFORMATION FOR AUTHORS xii-xiii
SIZING WORKSHEET xiv
COPYRIGHT ASSIGNMENT FORM xv
CLASSIFIED ADVERTISEMENTS xvi-xvii
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