Volu me 1

[eukemiaSeptember 200B-December 2007 INDEX

No. 1. 1-64 . . • . • . . • • • . Septe mber 2006No.2.. . ... . . . . . •.. . . .. . .65-136 ... . .• • . •.December 2006No.3. ... . • . . . . . • . . ... . . 137-200 . • . . . . . •. . . .March 2007

No. 4 201-256 J une 2007No. 5 257-312 September 2007No. 6.. . . •• . . . .• . . . . . . . . 313-376 December 2007

SUBJECT INDEX

AAbl Tyros ine Kin aseA perspective on the molecu lar evo lutio n of ch roni c mye loid leu kemia from

chronic phase to blast transform ation [Mughal and Goldman] 1(2):101-107-c rAbl-SrcDasatinib, a novel Abl-Src kinase inhibitor, in the management of patien ts with

Philade lphia ch romosome-positive leukemias [M ughal] 1(I):15- 18-mrAcetylsa licylic AcidCurrent treatment approac hes o f po lycyt he mia vera (Barbui et al] I(I ):41-45 -crActive Site-Binding PocketEmerging role of aurora kinase inhibitors in chr oni c myeloid leuke mia [Alvarado

and Cor tes] 1(6):325-330 -crAcute Lymphoblastic Leuk emiaDasaunib, a novel Abl -Src kinase inhibitor, in the manageme nt of patients with

Phi lad elphia chromosome-positive leuke mias (Mughal] I ( I):15-18-mrChallenges and progress in the treatmen t of adults with Philadelphia chromosome­

positive acu te lymphoblastic leukemia [Cortes et a l] I ( I ); 19-27-crNi lutin ib in the pos t-imatinib era for the tre atme nt of Philadelphia ch romosome­

posit ive leukemias [Mug hal ] 1(2 ):84-86-mrMinimal residual d isease in ad ult acute lymphoblastic leukemia: a guide to therapy

[Patel and Foroni] 1(2):108-117-crResistance to tyros ine kinase inhibi tors in Philadelp hia chro moso me-pos itive

leukem ias: which mutat ions matte r? [Soverini et all 1(4 ):223-228-crAcute Megakaryoblastic LeukemiaA case of rela psed Do wn Sy ndrome-associated acute mcgakaryo blastic leukem ia

cu red with non-myel oablative chemo therapy [Jayabose e t all 1(5):309-3 12­case

Acute Myeloid LeukemiaMyetodysptastlc sy ndrome with dele tio n 5q ab norma lity and its treatment [Ingram

and Mufti] I( 1):28-33-crEvolving role of arsenic trioxide in ac ute promyelocytic leukemia [Venepalli et

all 1(1):36-37-crThc role offamesyl transferase inhibitors in the trea tment of patients with leu kemia

and myclodysplasnc syn drome IShivakumar and Lancet l l (2):80. 83. mrOpt ima l thera py for chronic myeloid leukemia blast cris is: current co ncepts (Tam

et al] I(2):87-94-c rAcute Promyelocytlc LeukemiaEvolving role of arsen ic trioxide in acu te pro myel ocy tic leu kem ia [Venepalli e t

al] I (l ):36-37-crAdenosine TriphosphateEmerg ing role o f auror a kinase inhibitor s in chr onic myeloid leukemia [Alvarado

and Cor tcs l l (6):325 -330-crAdh esion MoleculesPrima ry plasm a cel l leukemia associa ted with adult Fanconi syndrome [Ca mpisi

e t all 1(2): l 30- 132-cascAlemtuzuma bDasatinib, a novel Abl-Src kinase inhibitor, in the management of patient s wit h

Philadelphia chrom osome-positive leukemias [M ughal] 1(1):15-18-mr

Alkylatlng AgentsTre atment options for pa tients with Ilud arabine-refractory chronic lym phocytic

leukemia [AbouYabis and P1owers] I(l );46-56-crAllogeneic lIematopoietic Stem Cell Transplanta tionTrea tmen t options for patients wi th Iludar ablne -refrac tory chr oni c lymphocytic

leukem ia [Abouvabis and F1owersl l(1 ):4 6-56 -cr

Allogeneic Stem Cell TransplantationThe decision 10 offer allogen eic stem cell n ansplar uatio n for patients with chronic

myeloid leukem ia in the tyrosine kinase inhibitor era [Goldmiln] I(2):73-74 ·edLong- term outco me of nonrnyelobative allogeneic stem cell transp lantatio n in first

chronic phase of chronic myeloid leu kemia [Ge sundhei t e t al] 1(2) :123-1 29-oc

AllograftlngThe decis ion 10 offer alloge neic stem cell transplantation for patients with chronic

myelo id leukemia in the tyrosine kinase inhib itor-era [Gold man] I (2):73-74-edAll-tmns-Retinoic AcidThe mana ge men t of acute promye locytic leukemia presenting during pregnancy

[Cu lligan et al] I(3 ): 183- 191-crAnagrelideCon trove rsies in the managemen t of essent ial thro mbocythemia [Ma rso n and

Harrison] 1(3): 155- 16 1-c r

Angiogen esisAngiogenesis in chronic lymphocytic leukemia: an em erging target [Molica e t all

1(2):118-12 2-crAnthracycllnesAcute myeloid leukemia disg uised as a solid tumor [C himapalli er all 1(3):198­

200-caseAntibody-Depend ent Cell-Mediated CytotoxicityMechanisms of alem ruzumab-mediate d cy totox icity in hem ato logi c ma lignancies

[Lin] 1(3):168-171 -cr

ApoptosisA per spective on the mol ec ula r evo lu tion of chronic mye lo id le ukemia from

chro nic phasc to blast transformatio n [Mughal and Go ldman ] 1(2) :10 1-107-crMechanisms of ale mtuzu rnab-mediatcd cytotoxic ity in hema tologic ma lignanc ies

[Lin] 1(3):168- 171-crEffective therapy with thalid o rrude/lovas tatin in a patient wi th primary plasma ce ll

leukemia rHus e t al] 1(3): 195-197-caseGene ex press ion profile of chronic myel oid leukemia inn ate ly resistant to imarinlb

[Camma rata eral] 1(4 ):234-242-oc

Arsenic Trioxid eEvolving role of arsenic trioxide in acu te promyelocytic leuke mia [Venepa lli e t

aI] I(1 ):36-37-crThe managem ent of acu te promyelocytic leukem ia prese nting during pregnancy

[Cu lligan et al] I (3) :183- 191-crAtaxia Telangiectasia-Mutated 'Iu mor Suppressor ProteinsFlavopiridol in chronic lym phocy tic le ukcmia [Christian ct al l I(5):292-297-e rAurora Kinase InhibitorsEmerging role of auro ra kinase inhibitors in chron ic myeloid leukem ia [Alvarado

and Cor tes] 1(6) :325-3 30-cr

Autologous Stem Cell TransplantationMinimal res idual disease in adult acute lymphoblastic leukemia: a guide to thera py

[Pa tel and Foronill (2): 108- 117-cr

BBcr·AblResist ance to tyrosine kinase inhib itors ill Philadelphia chro moso me- positive

leukemias: whic h mu tatio ns mutter? [Soverini et al] I(4 );223-228-cr

Bcr-Abl-Positivc CloneA perspec tive on the molec ula r evo lution of chronic myelo id leukemia fro m

chro nic phase 10 blast trans fo rmation [M ughal and Go ldman ] 1(2):101- 107-cr

boom - brief communicationcase - case repor tcomm - commentary

KEY TO ABBREVIAT IONS

cr - comprehensive revi ewed - ed itor ialmh - m eetin g highlights

mr - mini-revi ew(JC - origi na l contr ibutionr ib - research in brief

364

Owned, published, and © Copyrig hted, 2007 by CIG Media Group, LP

Clinical l eukemia • December 2007

Beneflt-Rlsk R a t ioCurrent trea tme nt ap proaches of po lycy themia vera (Barbui et a ll 1(l ):4 1-45-e r~-MicroglohuJ i n

Ch ronic lym phoc yt ic leukemi a: how to assess prognosis in 2007 (Tam et a l]1(3): 162-167 < r

Biologic A~t'nts

Ch allenges aTKI progress in the rrearrnem of ad ults with Ph iladelp hia chromosome­positive acute lym phoblastic leu kemia [Cort es e t a l) 1( 1):19· 27--<:r

Hiol og ic Mark ersTreatment options for pa tie nts wilh Ilud ara bine -re fractory c hron ic lymphocy tic

leukemia (AbouY llbis and Flowers ) 1(1):46-5 6-<: rBlast Cr isisOpuur eltberapy for chronic myeloid leuke mia blast crisis: current concepts (Tam

et a l] 1(2):87-94 -cl

mood Tran sfusionSpontaneo us hematologiclind cytogenet ic re mission in II case of acute myelogen ous

leuke mia with inve rsion 16 [Beiun rt et al) l (4): 243.2,16· case

IlMS ·214662T he ro le of farnesy l n austcrasc inh ibitors in the treatme nt o f patientswith leukemia

and myelodysplnstic synd rome [Shivakunmr a nd Lancer ] 1(2):80-83-mrBone LesionsHyper calcem ia a nd ost eol yti c bon e les io ns in B-cell c hro nic ly mphoc ytic

leuk emia: a case report [Ailawad hi et ul ] 1( 1):57-60- ca!'>CHone MarrowHype rcalc emi a and osteolyt ic bone lesions in Bccel l c hro nic lym phocy tic

leuke mia: a case repo rt [Ailawadhi et al) 1 (l ):57·60-ca~e

Myelod ysplasl id mye lo proJifer.uive d isorder over lap sy ndro me : how shoo ld it beapproached? (Litzow] I(2) :95-IOO-cr

Minin..a t residua l d isease in adult acute ly mphoblas tic leukemia: 11 guide to thera py[Patel and ForoniI 1(21:108 -I I7 -cr

Prim ary plasma cell leukemi a assoc iated wi th ad ull Fanconi sy ndro me [Ca mpisietal) 1(2): IJO-.J32-case

Prog nost ic sig nifi ca nce of mo lecu lar follo w-up by q ualitative a nd rea l-lim eq uantitative reverse-transcrjptase polymera .se c ha in reaction in TELJAMLI ­positivechildhood acute lymphoblastic leuke mia [Volpe et al l l(5):298-303-oc

Unmas king of c hro nic mye lom onoc ytic le ukem ia a fte r treatme nt o f chro niclymphocy tic leu kemia with rituximab (Bobek e t al) J(6):359. 362-cuse

Bone Marrow HlaslsG row ing ev ide nce for an undere sr irn arion of poo r-r isk cy toge ne tics in the

International Prognostic Scoring System ill myelo dysplasric sy ndromes [Ste id le t alj l (6):3S3· 356 -bco lll

cC DST he ro le of microRNA~ in c hronic lymphocy tic le uke mia [C hia rell i et al )

I(5):287 -29 1< rA highly se nsitive method for derec nng mi nima l res idua l d isease in Bccell c hron ic

lymp hoc ytic leuke mia: in situ hybrid ization on flow-so rted ce lls (Hense n et al]IlS):304-308-oc

CD 18Th e rol e of microR NAs in chronic ly m phocytic leuke mi a (Chiare ll i et al ]

1(5): 287-291-crC D19A highly sen sitive meth od for de tec ting minim al residual disease in Bccell ch ronic

ly mphocytic leu ke mia: in situ hybrid iza tion on now-sort ed cells (Hense n et alll( 5):304 -308- oc

CD38Chronic lymphocytic leu kemia: ho w to ass es s prognosis in 200 7 (Ta m er all

1(3): l 62-167-crCDS2Mechanisms of alcrruuzumab-mediatc d cyto toxicity in he matolog ic malignancies

[Lin] 1(3):168- 17I .c r

CD38 ExpressionAngi ogenes is in c hronic lymphoc ytic leukemi a: an emerg ing target [Molica et all

1(2):118- 122-crCerebrospinal FluidMe ningeal invo lvement in a patie nt wit h c hro nic Iymphoc ylic leuke mia and

Ric hter 's transforma tion [de Lo urdes Quinta nilla-Dieck e l al l 1(3):192 - 194­case

Chemoimmunothcra p}'Treatment op tions for patienl.~ with nu dara bine-rdractory chronic lym phocytic

leukemi a [AbouYab is and A ow ers ) I(I):46-56 < rChemotherapyChalle nges and progress in the treatment o f adu lls with Philade lphia chromosome­

pos itive acute lym phoblar.lic k uke mia [Cortes et a l] 1(I ):19 -27< rMinimal residual d i!'>Ca!'>C in adult aCUIe lymphoblas tic leukemia: a g uide 10 thera py

[Pa tel and Foro nil l (2) : I08 . 117-cr

Childhood DiseaseMinimal residual d i!'>Case in ad ult acu le lym phob lastic leukemia : a guide to thera py

[Patel and Foron i) 1(2): IOR- I 17-cr

C h lo roma

Infant with gran ulocy tic sarcoma of the o vary : an unusual case prese ntation ofacute myelogellOus leukemia ( M6) [Kumm- er :tJ)1 (4 ):247. 250-case

Chromosome Aberra tionsA highly sensi tive method forde tcct ing mi nimal res idua l disease in B-ce1J c hron ic

lymphocytic leuk emia : in situ hybri di zation on flow -sort ed cells (He nsen er al]l(5) :304·308 -oc

Chronic Lymphocyttc Leu kemiaTrClltme nl opt ioru;: for p3ticms with nuc1arabine -reflllClory ch ron ic ly mphocytic

leukemia fA hou Yabis and f-1CN"t"fIJ 1(1 ):46-56<1'Hypere.l~cmiD. and OlOlco ly l ic bo ne lesi ons in B-cell ch ro nic lymphocytic

leokemla: a case repon (Ailaw:tdhl et a l) l( t ):57-W-e&iCAngiogenesis in chronic:lymphocytic leukemia ::ln emerg ing targe t [Molic a er all

1(2}:118·122-cr

T he ro le of mic l'ORNAs i ll c h ro nic Iymphocyne leu ke mia (C hiarell i et al]I(5) :287- 29 1-cr

Fhtvopirido l in chro nic lymphocy tic le uke mia [Christian et al] 1(5 ):292.297-crA high ly senstuvemethod for dete cnn g mi nima l res idua l disease in B -een ch ronic

lymphocytic leu kc mia: in situ hybridization on flow -so rted cells {Hensen et 011 ]1(5 ):)().l·3(}&.oc

Unm ask ing of chro nic myelcmo nocytic leuke mia a fte r rreauueru of c hroniclymp hocy tic le ukemia with rituxumah [Bobek et al ] 1(6):359-362-<: i1<>e

Chro nic M}"clogenous Leuk emiaLong-term outcome of'n onmyelobanve alloge neic stem ce ll transpfaoredo n in first

chronic phase of chronic mye lo id leukemia (Ges undhe it et al l l (2):123- 129-ocChronic Myeloid LeukemiaDasanrnb , a novel Abl-Src kinase inh ibitor, in the ma nagement of pa tien ts with

Philade lph ia chromoso me--positive leukemias (M ughal] lei ): 15· IB-mrl be dec ision 10 offer allogeneic seem cell trans plantation for pa tient s with chronic

myeloid leu kemia in the tyrosine IOna!'>C inhibitor era (Go ldmanJ 1(2):73-74-edThe ro le of fam csyl transferase inh ibitors iurbe treatment of patients wuh leu kemia

and myelodysplasnc syn dro me [Shivakuma r and La nce t) 1(2) :80-83- mrNiloumb in the post-lm atin ib era fo r me treat me nt o f Ph ilade lphia chromosomc-.

pos itive leuke mias IMu ghal ) 1(2):84-86- lllrDptimal the mpy for chronic myeloid leukemia blas t crisis: current COIICep ts (Tam

et al) 1(2):87-94 -<: rA perspe ctiv e 0 11 the mo lec ular evol ut io n of ch ronic mye loid leuk emia from

chro nic phase to blast transformation [M ugha l and Go ldm an) 1(2) :101· 107-c rLong -te rm ou tcome of'nonm yeto banv e allogc ne ic stem cell transplanuulon in first

chronk phase of ch ronic myeloid leuk emia [Ge sundhe it et nl] 1(2) :123- I29-ocResistance 10 tyrosine kinase inhibitors in Philadelphia chromosor uc- posinve

leu kemia s: which mu tations matter ? [Soverini e r al)I(4 ):223-228-crEme rging ro le of a uro ra kinase Inhi bitors in chronic myelo id leukemia [Alvarado

and Cortes) 1(6):325-33O-crScrota l ede ma associated wit h the use of dasa ta inib in pat ients wi th chron ic

myeloid le uke mia [Ja in et a ll I (6):3 57- 358-caseChro nic Myeloproliferative DisordersThe ro le o f ge netics and epigenerics in the d iagnos is o f chronic myetoprolifcrauve

d iso rders (Spiva k and Molitemo) 1(5):275-286-crChronic PhaseThe decision to offer allogeneic stem ce ll uensplant atioe for pa tients with c hronic

myelo id leukemia in the tyrosine kinase inhibitor era [Gol dma lljl (2):73-74-edA perspective o n the mo lecula r evo lu tion of chronic myelo id leu kemia from

chronic phase 10 blas t transforma tion (Mllgha l and Goldman) 1(2):IOI- I07 < rLo ng-term outco me of nonm yelooauve al logeneic stern cell rransplantati cn in firs t

c hronic phase of chro nic myeloid leu kem ia (Gesundheit eral l 1(2 ): 123- 129-ocCoag ulopathyEvolving role of arse nic triox ide in acute pro mye locytic leukemia [Ve nepa lli cr

al] I( I ):36 -37-crCumnr biditiesTre atm ent optio ns for patie nts wit h fludn rab inc-rofractory chronic ly mp hocytic

leukemia [Abou'rubis and Flowe rs] I( [):46-56-crComplement-Depende nt CytotoxicityMec hani sms of ale mruznmab-mcdia red cyto toxicity in hem ato logic maligmmcies

lLinll(3):168-17 1-crComplete Cytogenet ic ResponseGenc expression profi le o f chro nic myeloid leukemia innately resi...tan l lo imati nib

[Cam marata et al] 1(4):234 -242-oc

Complete RemissionSpo nlaneous hemato log ic and cyloge netic remiss io n in a case of acute myelogenous

leuke mia wi th invers io n 16 1Bei nart el a IIH4):243- 246-c 1l!'>C

CorticosteroidsOp timal lhcrnpy for chronic myeloid leukcmia blast cri !i.is: currenl concepts (Ta m

et al) 1(2):87-94-cr

C)'clOIJhospha mid eTreatment opt ions for pa tie nts wi th l1udambi ne-re fracto l'y c hro nic Iymphoc ylic

leuk emia fAbou¥abi s and Ffowcrs) 1(1) :46- 56-cr

CylarahineAcute myeloid le ukemia d isguised as a solid tumo r [C himapalli et OI l) 1(3):198­

2QO-caseA case of re lapsed Down Syndrome- associ ated acu le megakaryo blaslic leuke mia

Clinical Leukemia • Dec ember2007 365

c ured wit h non -rnye lca blative che mo therapy [Ja yabose er al] 1(5):309 · 3 12·

caseCytogeneticsChallen ges and progre ss in the trea tment of ad ults wilh Phi ladelp hia c hromosome­

positive ac ute lympho blastic leukemia [Cortes er al) I( I):19-27-crC hron ic lym phoc ytic leu kem ia: how 10 assess prog nos is in 2007 (Tam e t a ll

1(3) : 162-167-crMyelod ysplastic sy ndro mes: impact of rece ntly analyzed variab les for modi fying

c urrent classifica tio n methods [Kan and Gre enberg ) 1(3):172- 182-crGenetic testing me thods in myclod ysplasnc syndromes and leukemias : a rev iew

[zame~nfkovaj l (6): 33 1 ·338-cr

Cyloklne MilieuAngiogenesis in chro nic lymph oc ytic leuke mia: an e merg ing ta rget [Molica er a l]

1(2):118- 122-cr

DDasatinibDasatin ib, a novel Abl-Src kinase inh ibitor, in the mana gemen t of penen ts with

Phi lade lphia chromoso me-positive leukemias (M ughal l l( I);15- 18-mrNilotinib in the post-im atinib era for the treatment of Philadel phia chrcmosome­

pos itive le ukem ias IMughal] 1(2):84-86-mrOpemcl rbe rapy for chro nic myelo id leu ke mia blast cri sis : c urre nt co ncepts [Tam

et a II1(2):87-9 4-crResistance to tyros ine kinase inhibitors in Philadel phia chromosome- positive

leu ke mias: which mu tatio ns mailer? [Se verini ct nil 1(4): 223-228-CIScrota l edema ass ocia ted with the use of dasatai nih in pa tien ts wi th c hron ic

myeloid leukemia (Jain er a l] 1(6):357-358-caseDecitabineChanging trea tment pa radigms for myelod ysplastic syndromes in a community

onco logy practices: Georgia Ca nce r Speci alis ts' Expe rience [Fe inberg et allI(6);345-352-oc

Deep Vein ThrombosisRec urrent venou s throm bos is in pat ie nts with polycy themi a vera a nd esse ntial

thrombocy them ia [Dc S tefano el all 1(6):339-344 «Deletion SqMyelod ysplas ttc syndro me with de letion 5q abncn ualiry a nd its trea tme nt [Ingram

and Mufti] 1(1);28-33-cr

Denilcukin DlftltoxTreatment optio ns for patien ts with fluda rahm e-rc frae tor y chronic lymphoc ytic

Icuk emi a lAbouYab is and Flow ersj l (I ):46-56-crDexamethasoneTreatment options for patients wi th fludara hinc-refr nctory chronic lymphocy tic

leu kemia [AbouYabis and Howersl l (l );46-56-crEffective the rapy wi th tha lidomidellovastalin in II pa tient with primary plasma ce ll

leukemia [Hus et al] 1(3):195- 197--caseDiagnosisThe role of gene tics and epigenencs in the diagnos is of chron ic mye lopr oli fera tive

d isorders [Spivak and Molitemol 1(5);275-286<rDisease-Free Surv ivalC hallenges and progress in the treat ment of adulL.. with Philadel phia chro moso me­

pos itive acute lymphoblastic leuke mia [Cortes er al] I( I):19-27-crEvolving role of arse nic triox ide in acu te prom yelocytic leukemia (VenepaHi et

al) 1(l ):36-37-crMiolmal re sldu at disease in adult ac ute lympboblasnc leu kemia: a gu ide to therapy

(Palel and Pe roni ] 1(2): 108-117-crDisease ProgressionA pe rspec tive on the mole c ula r evolutio n of ch ro nic mye loid leukemia fro m

chro nic phase 10 blast transforma tion (Mughal and Go ldman j 1(2):101- 107 -crDiureti csScrota l ede ma associated with Ihe use of dasatinib in pa tie n ts wi th chronic

myeloid leuk emi a [l ain ct al] 1(6 ):357-358-ca seD N A l\1icroarrayGen et ic test ing methods in myelodysplastic sy ndro mes and leukemias: a review

rZimeenfk o\'a] 1(6):33 1-338 < rD N A RepairA per spective on the molecular evo lution of c hro nic myelo id le uke mia fro m

chronic phase to blast tra nsforma tion [Mug hnJ and Gold man] 1(2):101- 107-crDown Synd rom eA case of relapsed Down Sy ndro me-associated ac ute mcgakaryobl astic leukemia

cured with non-myeloablative chemot herapy [Jayabose et aljl(5):309-3 12-ca,~e

EEpjgenetlcsThe role of ge netics and epigeneti cs in the diagnosis of chro nic myelo prolifera tive

diso rders [Spiva k and Moli temo] 1(5):275-286<rErnClinical leukemia: a new era , a new jou mal lCortes] I (I):5-edErythrocytosisTbe role of gene tics and ep igene tics in the diag nosis of chron ic myeloproli fera tive

disorders [Spivak and Molitem o j I(5):275-286-cr

Essential Thromboc ylhemiaRecurrent venous throm bos is in patients with po lycy the mia vera a nd essen tial

th rombocythemia [De Stefano ct al] 1(6 ):339--344 -ocEssential ThrombocytosisThe ro le of gene tics and epig eneric s in the diagnos is of chron ic myelopro liferative

diso rders (Spivak and Molitem o j l (5):275-286-crExt ramedulla ry Leuke miaInfant with granulocy tic sarcoma of the ovary: an unusual case presentation of

ac ute myelogen ous leuke mia (M6) (Kumar er al] 1(4):247-25D-case

F5-Azacil id ineChanging treat ment pantd igms for mye lod ysplasnc syndromes in a co mmunity

o ncology practices : Georgia Cancer Speci alists' Experi ence (Fei nberg el a l]1(6):345-352«

FlavcplrldolFlavopirido l in chronic lymphocytic leukemia [Ch ristian et all 1(5 ):292-297 -crFlow CytometryMye lod yspla slic syndro mes: impac t o f recently ana lyzed variables for mod ifying

curren t c lassification methods [Kao and Greenberg] I (3): I72 - 182-crFluid Retent ionSc ro ta l edema assoc ia ted wit h the usc of dasatini b in patie nts wi th chronic

myeloid leukemia [Jain cl al) 1(6)357-358-caseFtuda ra blneTreatme nt op tions for pat ients with fludarabine-refrac tory chronic lymphocyti c

leukemia {Abo uYab is and Flowers] 1( 1):46-56-l;rA case of relapsed Down Syndrome-associated acute megakary ob lastic leukemia

cu red with ron-myeloablative chc:motbempy [Jayabose et al j l (5):309-312-caseFfudarablne-RefractoryTre atme nt opoons for pa tien ts wilh Ilud arabi ne-refractory chronic lymphocy tic

leukemia [Abou Yabis and Flow ers ] 1(1):46-56-crFfuores cence-Actlva ting Cell SortingA high ly sensi tive me thod for detec ting mi nima l res idual disea se in Bccell chronic

lymph ocy tic leukemia: in s itu hybrid iza tion on ne w-sorted ce lls {Hense n et all1(5):304 -308 -oc

Fluorescence In Situ IlybridizationC hronic lymphocyti c le ukem ia: how to assess progno sis in 2007 [Ta m et al]

1(3): 162-167-crSpo n ta ne ou s he ma to log ic a nd cy togen e tic re mis s io n in a case of acu te

myelogen ousle ukemi a with inversio n 16 [Beinart et alj l (4) :243-246<ase

A hig hly sens itive method for det ec ting minimal res id ual disease in Bccell chro niclymphocy tic leukem ia: in Silu hybrid ization 0 11flo w-so rted ce lls (He nse n e t aI]1(5):304- 308--oc

Ge netic tes ting me thods in mye lcdy splastic syn dromes and leukemias : a rev iew[Z3 mecru"kova] 1(6):33 1-338-cr

Fre nch-America n-Brttlsh ClassificationMye lodysplasti clmy elo pro liferat ive disorder over lap syndrome: how should it be

approached? [Lit zow ] l( 2) :95· IOO-crMyelod yspla stic syndro mes : impac t of recen tly analyzed varia bles for mod ify ing

current cl assification methods [Kao and Green berg ] 1(3): 172 -182-crGrow ing ev ide nce for an underestim ation of poor- risk cytcgenedcs in the

Internat ional Prognostic Scor ing sys tem in myelodysplastic syndromes [Steid lct 1l11 1(6): 353-356-bcoltl

GGa.\tro intestinal BleedingRecurrent veno us Ihrom bos is in pa tien ts wi th po lyc ythe mia vera and esse ntia l

throm bocy themi a (De Stefano et a lj l (6) :339· 344 -ocGATAIA case of relapsed Down Syndrome--associated acute megakaryoblastic leukemia

cu red with non- myejocblanve chemotherapy [Jayabose et al] 1(5):309-312-caseGeneticsThe ro le of gene tics lind epigeeencs in the d iagnosis of ch ronic myelo proliferati ve

di sorders [Spivak and Molitcmo} I(5):275 -286-crGene OverexpressionGene expressi on profil e of chron ic myeloid leuk e mia innate ly resistant to irnatinib

[Cam mara ta et alj 1(4):234.242-ocGenetic MethodsGenctic testing methods in myelodysplastic sy ndromes and leukemias: a review

{Za mclnikova] 1(6):33 1-338-crGenomic AberrationsUpda te o n ge nomic profil ing in chronic lymphocytic leukemia (Stilgenbauer ]

1(4 ):217-222-m r

GIMEMAChalle nges and progress in the treat men t of adu lls wi th Philadelph ia chromosome­

pos itive acu te lymphoblastic leu kemia [Cortes et all 1(1):19-27-crGraft-Vers us-Host DiseaseTreatment opt ions for patie nts with Ilud a rabinc -re fractc ry c hronic lymphocytic

366 Clinical Leukemia • December 2007

leukemia [AbouYabis and Flowers] 1( L):46-56-crLong-term outcome of nonmyelobanve allogene ic ste m cell transplanta tion in first

chronic phase of chronic myeloid leukemia (Gesundhei t et 81l1(2):123-129-ocGra nulocyte Colony-Sdm ulatlng FactorA case of relapsed Dawn Syndrome-associated acute mega karyoblast ic leukemia

cured with non-myeloablative chemotherapy [Iayabose et al] J(5):309-3 12-caseGranulocytesUnmasking of ch ron ic myelomonocytic leuk emia afte r treatment of chron ic

lymphocytic leukemia with ritux imab (Bobek et al l 1(6):359-362-caseGran ulocytic SarcomaAcule myeloid leukemia disguised as a so lid tumor (Chintapa lli et all 1(3):198­

2()()..case

HIleniatologic Remiss ionPrognostic signi ficance of molecula r fo llo w-up by quali tative and ree l-time

quantitative rcverse-trunscrip tase po lymerase ch ain reaction in TEUAML l­positive chi ldhood acute lymphoblas tic leukemia (Yolpe el al] 1(5):298-303-oc

HematopoiesesA perspect ive on the mo lecu la r evolution of chro nic myel o id leuke mia from

chronic phase to blast transformation [Mughal and Goldman] 1(2):10 1-107-crThe role of genet ics and epigenencs in the diagnos is of chro nic myeloprolifera tive

disorders (Spivak and Moli temo) 1(5):275-286-crHematopoietic Stem CellsAng iogenesi s in chron ic lymphocytic leukemia : an emerging target (Molica er al)

1(2):1 18-122-crIlematopoietic Stem Cell Tr ansplanta tionLo ng- term outcome of nonmyelobat ive allogeneic stem ce ll transplantation in first

chronic phase of chron ic myeloid leukemia [Gesundh ei t et al] 1(2):123-129-ocHydroxyureaCurrent trea tmen t approaches of polycythemia vera (Barbui et al] 1(1):41-45-crContro vers ies in the manageme nt of essentia l thromboc ythemia [Marson and

Harrisonl l (3):155· 161-crHypercalcemiaHyp er ca lcemia an d os teo ly tic bone les ions in R-ce ll chro nic lymphocytic

leukemia: a case repo rt (Ailawndhi et alj l ( I) :57-60-caseHyperkalemiaFlavopiridc l in chronic lymphocytic leukemia [Chris tian et lllj l (5):292-297-cr

Id iopathi c MyelofibrosisThe role of genetics andepigenerlcsin the diagnos is of chronic myeloproliferetl.."e

d isorders [Spivak and Molitcmo) 1(5):275-286-c r

Imatin ibDasatinib, a novel Abl-Src kinase inhibi tor, in the management of patients with

Philadelphia c1uo mo some-positive leukemias (Mugh at l 1(1):15-18- mrChallenges and progress in the treatment of adults with Phi ladelphia chromosom e­

positive acu te lymphoblastic leukemia [Cortes et a lj l (I ):19-27-erThe deci sion to offer allogeneic stem cell transplant ation for panems with chrome

mye loid leuk emia in the tyrosine kinase inhibitor era LGoldman] 1(2):73-74­00

Nitonnib in the post-imatinib era for the treat ment of Philadel phia chromosome­positive leukemias (Mughal) 1(2):84-86- me

Optima l therapy for chron ic myeloid leukemia blast crisis: curren t concepts (Thmet al) l(2):87-94 -cr

A perspective on the molecular evolution of chronic mye loid leukemia fromchronic phase to blast transf orm ation [Mughal and Goldman] 1(2):101-1rrl-c r

Long-term outcome of nonm yelob arive allogene ic stern cell transplantation in firstchronic phase of chronic myeloid leukemia [Gesundheit et al] 1(2): 123-129-oc

Resistance to tyrosine kinase inhibit ors in Philade lphia chromosome- pos itiveleukemias: which mutations matte r'? [Severini et a l]I(4):223-2 28-cr

lmatinib ResistanceEmerging role of aurora kinase inhibitors in chronic mye loid leukemia (Alvarado

and Cortisj l (6):325-330-cr

ImmunoglobulinDasa tinib, a novel Abl-Src kinase inhibito r, in the manag ement of patie nts with

Philadelphia chromosome-positive leukemias (Mughal ] 1( 1): IS·1 8-mrImmuno globulin Heavy ChainChronic lymphocytic leukemia: how to assess prognosis in 2007 (Tam et al ]

1(3):162- 167-crImmunoglobulin Variable Region GenesTh e ro le of mic ro RN As in chronic lym ph ocyti c leukemi a [Chiareui e t all

1(5):287-29 1-er

ImmunohlstochemlstryPrimary plasma cell leukemia assoc iated with adu lt Panco ni syndrome [Campisi

er al) 1(2):13D-132-ease

ImmunophenotypingChallenges and progress in the treatment of adults with Philad elphia chromo some­

posi tive acute lymphoblastic leukemia (Cones et al] I ( I): 19-27-cr

A highly sensi tive method for detec ting minimal residual disease in Bccell chroniclymphoc ytic leu kemia: in situ hybrjd lza rion on flow -sorted cells [Hensen et al]1(5):304·308-oc

Immu nostaini ngUnmasking of chronic myelomonocytic leukemia afte r trea tment of ch ron ic

lymphocytic leukemia with rituxima b [Bobek er all 1(6);359-362-ca<;(:Immunoth erapyTreatme nt options for patients with n Udarabine-refraClory chronic lymphocy tic

leuke mia IAbouYabi s and H ewers) 1(1):46-56-crInt erferonCurrent treatment approaches of polycy themia vera (Barbui et alj 1(I ):4 1-45-crIuteferon-cCo ntroversies in the management of essential thro mbocythemi a [Marso n and

Harrison) 1(3):I 55-16 1-cr

Inter'leukin-fHypercalc emia and osteolyti c bone les ions in B-cell ch roni c lymphocy tic

leukemia: a case report [Ailawndhi et a l] I( 1):57-60-cascIntern ational Prognosis Scor lng SystemMyelcdysplastic syndrome with deletion 5q abnormality lind its trea tment [Ingram

and Muft ij l(l):2S-J 3-erMyetodysplestic syndromes : impact of recently analyzed variables for modi fying

current classi fication methods (Kao and Gre enbergl l (3 ): In -182-crIntra thecal ChemotherapyMeningea l involvement in a pati en t with chronic lymphocy tic leuk emia aod

Richter's transformation (de Lourdes Quintanilla-Dieck et al) 1(3):192-194-ca.<;(:

JJAK2Myelodysplastid mye1oproliferat ive disorde r overlap syndrome: how should it be

approac hed'? (Litzowl l (2):95- 1OO-crThe role of genetic s and epigenetics in the diagnosis of chronic myel oprolifera tive

disorde rs (Spivak and Molitemo) I(5):275-286--cr

JAK2 MutationCurrent trea tme nt approaches of polycythemia vera (Barbui et all I ( 1):4 1-45-crCcmroversies in the management of es sent ial thro mbocy the mia IMa rson and

Harrison ) 1(3):155-161-crJu venile Myelomonocytic Leuk emiaMyelodysplas tic/myeloproli fcrativc disorder overlap syndrome: how should it be

approached? [Litzow l l( 2):95- 100-cr

KKaryotypeMyelodysp lastic syndrome with dele tion 5q abnorma lity and its treatment (Ingram

and Muftij 1(l):28-33-crAng iogenesis in chron ic lymphocytic leukemia: an emerging target IMoJica era ll

1(2): I IS- I22-e rGrowi ng ev idence fo r an un dere stim ation of poo r-ri s k cy togenet ics in the

International Prognostic Sco ring System in myelodys plastic syndromes [Steid let all 1(6):353-356-bcom

Karyotypic AnomaliesGenetic testing methods in myelodysplastic syndromes and leukemi as: a review

[ZAmeb1i'kova]I (6):33 1-338-cr

LA U~ht Chain DiseasePrimary plasma cell leukemia associ ated with adult Fanconi syndro me (Campisi

et al] l( 2):13G-132-case

LenalldcmldeMyelcdysplasnc syndrome withdeletion 5q abnormality and its trearment lfngram

and Muft i) 1(l) :28-33-crChanging trea tmen t paradigms for myclodysplastic syndromes in a community

oncology practices : Georgia Can cer Speci alis ts' Experi ence [Fein berg et all1(6):345-352-oc

Lonafarn ibThe role of famesyl transferase inh ibitors in the treatmen t of patients with leukemia

and myelodysplastlc syndrome IShivakum ar and Lancetj l(2):8G-S3-nu

Lymph adenopathyTreatment op tion s fo r patients with n udarab ine-refraetory chronic lymphocytic

leuke mia [AbouYa bis and Flowers ) 1(I ):46--56-ctLympbocy tesHyperc alc emia an d osteolytic bone le sion s in B-cel l chronic lymphoc yt ic

leukemia: a case report (Ailawadhi et al ] I( I ):57-6O-case .Unma sking of chronic myelomonocytic leuk em ia afte r tre atment of chrome

lymphocytic leukemia with rituximab [Bobek eI all 1(6):359-362-case

Lymphoid Blast C riSili . _Dasat inib, a novel Abl-Src kinase inhibitor, in the managemen t of panen rs with

Philade lphia chromosome-posit ive leukemias (Mughall I ( I ):15-I S-me

Lymp hoid Mali~nancy .Unmaski ng of chron ic myelomo nocy tic leuk emia after trea tment of chrome

Clinical l eukemia • December2007 367

ly mp hocytic le ukemia with rituximab [Bobek et al] 1(6):359-362-case

Lymphopruliferat ive DisordersT he ro le of microR l'As in ch ronic lymphocy tic leukemia [Chiaren i et al)

1(5):287-29 1-cr

MMat rix MetalloprotelnaseAngiogen esis in chro nic lymphocytic leu kemia: an eme rging targe l [Mo lica et al]

1(2): 118-122-crMeeting Highlights [Prepared by Latha Shivakumar]The role of " ll -/ I·(/Irs -rel ino ic acid in co mbmatiou with ar senic tr iox ide as

ind uc tion therapy fo r pre vious ly umre ared patie nts with ac ute promyelocyticleuke mia 1(1):9-10-mh

Pre liminar y resu lts fro m a phas e I II s tudy co mpa ring ale mtu zuma b vers usc hlora mbuci l in previously untreated patients wi th progre ssive H-cell chroniclymphocy tic leu kem ia 1(1):10- LI -mh

Cloretazine as ind ucti o n therapy for previo usly unt reated elder ly pati ents withpoo r-risk acut e myelo id le uke mia and high- risk myelodys plas ric sy ndro me1(1):1 1-12-mh

Meeting Highlights [Prep ared by John 1\'1. Goldm an, Ta r iq 1.Mughal , an d La tha Shivakumar]

Allernate dos ing schedule of flavopir ido l ill the treatment of chr on ic lymphocyticleu kemia 1(2):76-77 -mh

MK-0457, a novel Ab l tyros ine kinase inhibi tor in the tre atmen t of drug-resistantleukemia 1(2):77-7S-mh

Is luratiuib cardiotox ic whe n used 10 treat patie nts with chronic myelo id leukem ia?I (2):7S-79-mh

Meeting Highlights [Prepa red by Sabeeha Muneer, Kesava Redd y,and Sonia Cunningha m]

Results from 2 phase 11stud ies of leua lidouud c ill patients with relapsed/ refractorychro nic ly mphoc ytic leukemia 1(3): 146- 147-mh

Phase lIII trial o f lumili ximab (an li-C D23) with tludarab inc/cyclo phosphamid e/rit uximab in patients wi th re lapsed chron ic lymp hoc ytic leukem ia 1(3):147­148-mh

Phase I trial o f Ilavopindo l in patie nts with relapsed chronic lymphoc yt ic leuk emia1(3): 148- J50-mh

Clofarabine with lda rubicin o r ida mhi ci n/cy tara bine as salvage therapy fo rpatients with acute myeloid le ukemia 1(3):150-15 1-l1lh

Meeting H ig h li ghts [Prepared by Tariq Mughal and JohnGoldman]

Sess io n I: W hat is the bas is of geno mic instabilit y and disease progressio n?1(4) :210- 111 11

Se ssion 2: !l ow do Bc r-Abl ty rosine kinase inhib itors work? l(4 ):2 10-21 1-mhSession 3: Wha t is the bas is for tyrosi ne kinase inhibitor resis tanc e? [(4):2 11­

2 12-mhSession 4 : W hy are no rmal ste m cells "s uppressed" ? Do leu kemi a stem cel ls

always surv ive imatinib? What is the role of immunothera py? 1(4):2 12-mhSess ion 5: A focus on the "ma nagement" issues for 2007: standard ization of real­

lime q uan uta tive polymerase cha in reac tion; defi ning resp ons e to rrea tme utwith imatioib ; and mon itoring resp onse to treatment 1(4):2 12-mh

Sessio n 6: S hou ld all new chronic phase pa tien ts start the rapy with ima t inib?1(4):212-213- mh

Sessio n 7: Second-genera tion tyrosine kina se Inhibi tors and ot he r new agentsJ(4):2 13-214-mh

Session S: W hat is the role of allogeneic s tem ce ll transp lan tatio n in a paue mwhos e disease did nOI resp ond to irnarinib thera py? 1(4) :214- mh

M eetin g Highlights [Prepared by Letha Shivakumar, MarissaSh rader, and Sonia Cunningham]

Sessio n I: Imp rove me nt in eve nt- free and ove ra ll surviva l a fter co nsolidat io nwith a rsenic triox ide ill patie nts with newly diag nosed acut e prc myclo cyticle ukemia 1(5): 269-270-mh

Session 2: Feasibility of dasatinib 100 mg o nce da ily in patien ts wi th imarinih ­resis tantli nto leran t Ph ilade lph ia c hromosome- posi live chronic myeloidleukemia or ac ute lymphoblastic leu kemia 1(5): 270-27I-mh

Session 3: Phase I/ l l tri a l of bosu tinib in patien ts with ima rinib-res is tan r/intole rant Philadelph ia chromosome-pos itive chro nic myelo id le uke mia o rac ute lymphoblastic leuke mia 1(5): 27 1-273 -mh

Session 4: Developmen t of multigene express ion-b,lsed prog noslic signatures foradu lts with core binding factor acute myeloid leuke mia 1(5): 273-274-mh

Menin geal Ca rcinnmatnsis~en i ngea l invol ve menl in <l p<ltient with chronic Iyulphocy tic le uke mia a nd

Richter's tnlrlsfoLlnation [de Lo urdes Quint,milla-Dieck et al ] I(3) :192-194-case

Microarray AlU11)'sisA pe rspec live un the mo lec ular e vo lu tio n of c hronic mye lo id Icukemia from

chro nic phase to blast tran~formal ion [Mughill and GoldmanJ 1(2) :10 1-107-cl"

MicroR~A s

T he role o f mic roRNAs in ch ron ic lym phocy t ic le uke mia (C hia rc tt i e l al]I (5):2S7-291-cr

:\linimal Residual DiseaseTreatmen t op tions for pa tie nts wilh fJuda rab ine- re frac tory ch ronic lymphocytic

leukem ia [Abo u'rubis and Flowers] 1(1 ):46-56-clMinimal res idual dise ase in adu lt acute lymphoblas tic leukemia' a guide 10 therapy

[Patel and Foro lli] I(2) : lOB-I I7-c rThe management of acute promyelocyric le ukemia presenting during pregna ncy

[C ulligan er a11 I(3):183- 19 1-cr

M itoxa nt r oneT reatment op tions for paneut s wi th flu dara bine -rc frac tcry chr onic lym phocy tic

leukemia [AbouYabis and Flowe rs] 1( 1):46 -56-crA case of relapsed Down Syndro me-associated acute megakaryobtastic leuke mia

cured with non-myelo abkuive chemothe rapy [Iayubose er al l 1(5) :309-3 12-caseMl xed-Llneage LeukemiaInfa nl with granulocytic sarcoma of the ovary : an unusual case presen tat ion of

ac ute myelogenous leukemia (M6) [Kuma r e t ul] l( 4):247-250-caseMolecular Follow-upPrognostic s ig nifi cance of mole c ula r follow -up by qua lita ti ve a nd real-t ime

quan titative revcrsc -trausc rip tase pol yme rase cham reacti o n in TEU AML I­positive child hood ac ute lymp hoblas tic

Molecular MedicineT he era of molecular med icine has a rrived in the management of le uke mias

[Cortes] 1(5) :26 3-264 -cd

Molecular MethodsGen etic testing me thods in myelod ysplas tic syn dromes and leuk emias: a re view

[Z<'i mecnfk:ova] I(6):33 1-338-cr

Molecular PathogenesisC halle nges and progress in the trcntmc nt of ad ults with Philadel phia chromosome­

positive ac ute lympho blastic leuke mia [Cortes et a ll I (I): 19-27-cI·

Molecul ar PathwaysA perspec tive o n the molecula r evolu tio n of chro nic mye loid le ukemia from

c hronic phase to blast nansfonnanon [Moghat and Goldman] 1(2): JOI-l 07-c rMolecul ar RemissionProg nost ic sig nificance of molec ular fo llo w- up by q ua lita tive a nd rea l- time

qua ntitative rcveue-uanscript asc poly me rase c hai n reaction in TEU AML 1­positive ch ildhood acute lymp hoblastic leukem ia IVolpe ct all 1(5):298-303 -oc

Molecular TargetsMini ma l residual d isease in adu lt acute lymphoblastic leu kemia: a guide to therap y

[Patel and Peroni] l(2) : I08- 117-cr

Mon oclonal AntibodiesTreatm ent options for patients with tl udarablne -ref rucrory chronic lymphocytic

leukemia [Abo uvabis end Flowcls l l(1 ) :46 -56-cr

Monoc ytesUnmas king of c hro nic mye forn o nocyt tc le uke mia afte r treatme nt of c hro nic

lymphocytic leukemia with rit uximnb [Bobek e r al]I(6):359-362-CllSC

M PLSISUK MutationCo ntroversies in the manage me nt of essent ial thro mbocy the mia [Marson alld

Harr ison] 1(3):155- 16 1-cr

Multiple MyelomaHyperc alce mia and os teolyti c bone les io ns in B-ce ll ch ro nic lymphoc ytic

le uke mia: a case repo rl [Ai lawad hi et aljl(l):57-60-casePrimary plasma ce ll leukemia associa ted with adult Fanconl syndro me [Campis i

et al] 1(2): l 30- l32-case

Myelod yspla stlc SyndromcMyclod ysplastic syndro me with deletion Sq abno rmnfity and its treatment [Ingra m

and Mllfti) 1(1):28 -33-c rM'l 11y plusses co me fro m studying 5q- mye lodys plas tic sy ndrome [Ni mer]

1( 1):34-35-co mmMyelod ysptastic/ruye lo prolifera tive disorder overlap sy nd rome: how shou ld it be

ap proached? [Litzow 1 1(2):95-1oo-«Myelody spla stic SyndromesGenet ic te sting me tho ds in mye lod ys p lastic sy nd ro mes a nd le uke mi as

[Zrimecnfkova ] I (6):33 l-338-crChangi ng treatment parad igms for myc lod ysplastic sy ndro mes in a community

oncology prac tices : Georgia Cance r Spec iali sts' Expe rie nce Weinberg et al]I (6l :345-352-oc

G row ing ev ide nce for an und e res tim ation of poo r-ri s k cy togenetics in theIoternauo nal Prognostic Scoring Syst em in myelo dysp las tic sy ndromes [Steidle r al] 1(6):353-356-bco m

Un mas king of c hronic myc lomonocytic leukemia af ter tre atme n t of ch ron iclymphocytic leukemia with ruuxima b [Bobe k el al] I(6):3 59-362-case

Myeloid Blast CrisisDasal inib, a no vel Abl-Src kinase inhibi lof, in the manage men l of patien ts wilh

Philadelphia c hromosome-posi tive leukemias [Mughal ] 1(1 ):15-1 8-mrMyeloid NeoplasmsMyd od ysplastic/myd o pro liferatjve d isorder o verla p synd rome: how should it be

approac hcd? (Litzow] 1(2):95- 100-crMyelomaEffec tivc therapy with thalidomide/lovastalin in a pa tienl wit h primary plasma cell

leukemia (Hus et a ll 1(3) :195- 197-ca"eMyeloprolifel'ative DisorderMyelo dysplaslid myclop roliferative diso rde r overlap syndrome: how shou ld il be

approached? [Litzow] I (2):95 -100-cr

368 Clinical Leukemia • December 2007

Myel o prolifera ti ve Di sordersRecur rent venous thro mbos is in patien ts wit h pol ycy themi a vera and essentia l

thrombocythe mia [De Stefa no et al] I(6 ):339-344-oc

Myelosu ppressionThe usc of dasann ib in chronic myeloid leukem ia: some pract ica l co nsiderations

[Marin e l lll)l(4) :229 ·233""Cr

NNela rabineTreaerem opt ions for pa tients with Iluda rabm c-rcfractory c hroni c lymphocy tic

leukemi a [AbouYabis and Aowers) I(1) :46-56-cr

N ilo tl n lbDasatinib, a novel Ab l-Src kinase inhibitor, in the management of pnnen ts with

Philadel phia chromosome-positive leu kem ias IMug hall l (l ):IS-18-mrNilOlinib in the pcst -ima rinib era for the treat ment of Philade lph ia chromosome­

pos itive le uke mias IM ughal) I(2):84-86- mrOptimal therapy for chron ic myelo id leukemia blast crisis: c urre nt concep ts [Ta m

er al) 1(2}:87·94-crRes istance to tyrosine kinase inhib itors in Phi ladelphi a chromosome-posi tive

leukemi as : wh ich mutetioes mailer? [Severini et al l 1(4 ):223-228""CrNon-Myeloablative C hem o t her a pyA case of relapsed Down Syndrome-associated ac ute megekaryo blasric leu kem ia

cured with non-m yeloab lative chemotherapy (Jayabose e r all 1(5):309-3 12­case

North A mer ica n Inte rgroup Trial C 9710Evo lving ro le of ars enic trioxi de in acute prom ye locytic leukemia [ Venepalli et

al) I( l ):36-3 7""CrNosologyMyeJodysp lllsticl myelopro liferal ive d isord er overlap syndrome: how should it be

approached"! ILilzow ll(2):95- I()()..(:r

oOucoproteinA perspec tive o n the mo lec ular evo lut ion of ch ronic myeloi d leu kem ia from

ch ronic phase 10 blast transformation [Mughul and Gold01llnl l( 2): IOI- I07·crOutcom esChang ing treatment para dig ms for mye lodysplastic syndrom es in a co mm unity

o ncology practice s: Georg ia Cance r Specialists' Experi ence [Pei nbc rg et all1(6) :345-352 -oc

Overall SurvivalG rowing evide nce fo r an unde rest ima tio n of po o r- ris k cytogenetics in the

lnternatloua l Pro gnost ic Sco ring System in myelodysplastic sy ndromes [Steid le t all l (6) :353-3.56-bco lll

pp53Ha vopir ldo l in chronic lymphocytic leukemia [Christian et all 1(5):292-297-crPathogenesisMyelodysplastic sy ndrome with dele tion 5q abnormality and its ue atment [Ingra m

and Mufli] 1(1):28·3 J--crPentostatinTre at ment op tions for pa tients with f1udarabine- refrac to ry chronic lymphoc ytic

le ukemia (AbouYllbis and Flowers ] 1(I ):46-56-cr

Per iph eral Neuro path)'Evolv ing role of arsen ic t riox ide in acute pro myelo cytic leukemia (Ve nepalli et

aI11(l):J6-37""CrPeripheral SmearUnmas king of ch ro nic mye lom onocyric le ukemia afrer tre atmen t o r chroni c

lymphocytic leukemia with rituximab [Bobek et al] 1(6):359-362-caseP hilade lp hi a Cb ro mosorne-PosltlveDasarinib, a novel Abl-Src kinase inhibi tor, in the ma nagement of patien ts with

Philadelphia c hromosome-posit ive leukemias (Mughal] I( I ): IS- 18-mrCha lleng es and progress in the treat me nt of adult s with Philadelphia chromosome­

positive acute lymphob lastic k:ukemia [Cortes et alJ 1(l ):19-27""Cr:-.IilOlinib in the post-imatin ib era for the treatment of Philade lphia c hro moso me­

posit ive le uke mias [Mugha l] 1(2):84 -86- mrMi nimal residua l di sease in adu lt ac ute lymphob lastic leukemia: a guid e to thera py

[Patel and Foronij l (2):1Q8-II7--crPhlebotomyC urre nt treannem approac hes of polycy themia vera [Bar bui er al] I ( I ):4 1-45-c r

Plasm a C ell L eukem iaPr imary plasma cell leukemia assoc iated wit h ad ult Fanconi sy ndrom e [Campisi

e t al l l (2) :130-132-casePleural EffusionThe use of dasatinib in chron ic myeloid leukemia: some practical conside ration s

IMari n et al ) 1(4) :229-2J J -crScro ta l edema associ ated with the us e of dasa tinib in pUllent s with c hro nic

mye loid leukemia {Jain et al]1(6):J 57- J58.c ase

PM L·I{ARAThe management of acute pro myelocync le uke mia prese nting during pregna ncy

[Cu lligan et all 1(3):18J -19 1-crPol y cythemia VeraCurrent rreaunera llpproaches of polycy themia vera [Harbui er all 1( 1):41-45-c rThe role of gcnclics IIJ1d cpigcooia in the diagn osis of chronic myeloproliferat ive

disorders (Spivak imd Molitemo] 1(5):275-286--crRecurre nt veno us thrombosis in pa tien ts with po lycythem ia vera and essentia l

Ihrombocythemia [De Stefano er al) 1(6):339-J44-ocPol y m era se C hain R ea c t ionThe ro le of mic roRNAs in c hr on ic lym phocy tic leu kemia (Chiarelli er al]

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Polym c rphismsM yelodysp lastic sy nd rome .....ith deleti on 5q abnorm ality and its trcameru [In gra m

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P rogressive Di sea seAngiogenesis in chron ic lympboc yric leukemia: an emerg ing ta rget [Mollca et al]

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chronic pha se 10 blast trans for mation [M ughal and Gold man l l(2 ):101- 107-crPu rine Nucleos ide Ana logu esTrea tment options for pa tient s with n udarabine -re frac to ry chro nic lymphocytic

leukemia [AbouYabis and Aowersl l(I ):46-S6-cr

RR a d ia t io n TherapyInfant with granu loc ytic sarco ma of the o vary: an unu sua l case presentat io n of

acute myelogenous le uke mia (M6) IKumaret all 1(4 ):247-250-caseReal -Time Quantltetlve Polyme rase C h ai n R ea ctionThe manageme nt of acu te promyclocytic leuke mia presenting d uring preg nancy

[Cul1iganetaJ]I(3): 183-19l--crP rognos tic sig nificance of molecu lar follow - up by qualitative and real-time

qua ntitative rcverse-tra nscriprase pol yme rase cha in reaction ill TEUAMLI­posit ive child hood acute lymphoblas tic leukemia [Volpe ct all J(5):298. 303-oc

Reduccd-Intcnslty ConditlonlngT reatment optio ns for patie nts with Iludnrabinc-rcfractory chronic lymphocytic

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Lo ng- term benefits ofi mati nib in pa tients with chronic myelo id leuke mia 10):13­lc-rib

Residual DiseaseProg nos tic sig nif icance of mo lec ular foll ow -up by qual ita tive a nd rea l-t ime

q uantitati ve reverse-transc np tese polymerase c hain reaction in TEUA~IL I­

positive childhood acute lymphoblastic leukemia (Volpe er all 1(S):298.303-ocR es ponseNitonn ib in the pos t-imat inib era for the treatme nt of Philadelph ia ch romosome­

pos itive leukemias [Meg hal] I(2):84· 86-mrRetlnolc AcidEvolving role of arsen ic trioxid e in aCUIe pro myelocytic leukem ia [venepalli et

all l ( I) :36-3 7-crReverse-Tra nscriptas e Polym erase C h a in Rea ctionPrognostic si gn ificance of molecu lar renew-up by q ua lit~ t i v~ a nd real-li me

q uant itative reverse-transcriptase polymerase chain reacuon 10 TEUA:'>IL 1­positive chi ldhood acute lymphoblastic leuke-mia l'blpe et all l(5):~98-30J-~

Genetic testing method s in myelod ysplasuc syndromes and Ieu kemias : a revic....

[ZMneenfk ovaJ 1(6) :33 1-338-cr

Richter's S y ndrom e "_ "Hype rcalc em ia and os teo lytic bone les io ns in B-cell chronic I)'mp hoc ync

leukemia : a case report [Ail awad hi et all l(l):S7-6O-case

Rlluxlmab . , .Treatme nl opt ions fer pa t;cnts ....ith nudotrnbinc-re frac tory chrome Iymphoc}IIC

leuke mia (AbouYabis and Rowen ) 1(1 ):46-.56-<1" "Unmasking of c hro nic myt'lo mo noc:ytic leu ke mia afte~ ~~;~;I~;l~~:chronic

lym phocytic leukemi a with rituxumab IBobek e-I all 1( ).

5

Salvage Therapy . f J I "with Ph iladdphiil Ch nJl lltlStl ll W -

ChAJ leng~ and progress m the, treatmen ~ "o [~ u ~s t 01111(1 ): 19. 27--l.-rpos ilivc acu te lymphob lastiC jeukcrrua ort s e

S c r o ta l f>:dema , " f d sn!ainib ill palic nts with dllul1i~'Sc rotal edema as sociated with the use 0 fl "

myelo id leu kemia [Jain et al] 1(6): JS 7-J58·case

S ider o b lasts " " J '" 'del' ovcrlap s\ n.JroIllC: 11l11\' shou ltl it h..,Mye lodysplas tid mye loprohferatlYe ISOI "

approac hed? [LitlO wj l(2 ):95 -IOO-cr

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Germing, U.Growing evi de nce for an underes tima tio n of poor-r isk cy togene tics in the

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Hensen, K.A highly sensitive meth od for detecting minimal residual disease in B-cell chronic

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